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Medicine (Baltimore) 2018 Dec;97(52):e13730

Department of Orthopedic Oncology, Beijing Ji Shui Tan Hospital, Peking University, Beijing, People's Republic of China.

Case Series: To analyze the clinical results and related factors of further surgical treatment for recurrent sacral chordomas.Chordomas are rare primary malignant tumors with a high recurrence rate. The treatment of recurrent tumors is difficult and controversial. Read More

Diagn Interv Radiol 2018 May-Jun;24(3):158-165

Institute for Clinical Radiology, University Hospitals Munich - Campus Großhadern, München, Germany.

Purpose: We aimed to assess the safety and technical outcome of computed tomography (CT) fluoroscopy-guided osteoplasty with or without prior percutaneous radiofrequency ablation (RFA) in patients with painful osteolyses.

Methods: We performed a retrospective analysis of 29 patients with painful extraspinal and spinal osteolyses (16 women, 13 men; 63.1±14. Read More

J Pediatr Hematol Oncol 2018 07;40(5):e330-e333

Department of Radiation Oncology.

Background: Craniospinal irradiation (CSI) is commonly required for pediatric patients with central nervous system malignancies. Traditionally, CSI is given using x-rays to deliver radiation to the brain and spine, exposing normal anterior structures, including heart, to unnecessary radiation.

Observations: We present a patient treated with x-ray CSI for medulloblastoma with spinal metastasis (3600 cGy CSI with focal boost to 5000 cGy), who subsequently developed significant cardiac toxicity, likely related to radiation exposure. Read More

BMC Surg 2017 Aug 23;17(1):92. Epub 2017 Aug 23.

Orthopedic Oncology Department of the Podkarpacki Oncology Hospital, Bielawskiego 18, 36-200, Brzozów, Poland.

Background: In nearly 30% of patients with myeloma, pathological fractures are found to occur in the spine. If the patients are not treated promptly and satisfactorily, the quality of their lives diminishes. Currently, the standard treatment for metastatic lesions of the spine is radiotherapy, but surgical intervention is becoming more frequent. Read More

Eur Rev Med Pharmacol Sci 2011 Jul;15(7):831-9

Department of Oncologic and Degenerative Spine Surgery, Rizzoli Institute, Bologna, Italy.

Objectives: To evaluate the role of enbloc resection on the oncological outcome of patients with Ewing's sarcoma of the mobile spine treated with systemic multiagent chemotherapy combined with radiation therapy. While the role of chemotherapy and radiation therapy is well known and accepted in the treatment of Ewing sarcoma, there is no consensus on the role of enbloc resection in those tumors occurring in the mobile spine and, therefore, it can be difficult to conclude the decision making process, particularly if to achieve a tumor-free margin resection functionally relevant structures should be sacrificed. The study design of this work was the retrospective analysis of a series of 27 cases of Ewing sarcoma of the mobile spine homogeneously treated. Read More