28,676 results match your criteria Spinal Infections


[Infections after hip and knee replacement surgery and after spinal fusion: a comparison].

Orthopade 2020 Jul 8. Epub 2020 Jul 8.

Clinic für Wirbelsäulenerkrankungen und -Therapien, MEOCLINIC, Berlin, Deutschland.

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http://dx.doi.org/10.1007/s00132-020-03944-2DOI Listing

Zoster sine herpete: a review.

Korean J Pain 2020 Jul;33(3):208-215

Department of Pain Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi, China.

Zoster sine herpete (ZSH) is one of the atypical clinical manifestations of herpes zoster (HZ), which stems from infection and reactivation of the varicella-zoster virus (VZV) in the cranial nerve, spinal nerve, viscera, or autonomic nerve. Patients with ZSH display variable symptoms, such as neuralgia, however, different from HZ, ZSH show no zoster, which makes clinical diagnosis difficult. ZSH not only causes initial symptoms, such as neuropathic pain in the affected nerve, Bell palsy, and Ramsay Hunt syndrome, but also postherpetic neuralgia and fatal complications such as VZV encephalitis and stroke. Read More

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http://dx.doi.org/10.3344/kjp.2020.33.3.208DOI Listing

Back Pain in Children and Adolescents.

Am Fam Physician 2020 Jul;102(1):19-28

Fairview Sports and Orthopedic Care, Blaine, MN, USA.

Back pain is a relatively common presenting symptom in children and adolescents. Typical causes include muscle strain or spasm, spinal deformities (e.g. Read More

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Therapeutic pulmonary telerehabilitation protocol for patients affected by COVID-19, confined to their homes: study protocol for a randomized controlled trial.

Trials 2020 Jun 29;21(1):588. Epub 2020 Jun 29.

Fisiosur I+D Research Institute, Garrucha, Almería, Spain.

Background: In December 2019, 27 cases of pneumonia, of unknown cause, were identified in the province of Hubei (China). The WHO declared the situation as a Public Health Emergency of International Concern, and it was finally declared a global pandemic on March 11, 2020. The Spanish Government obliges the entire population to remain confined to their homes, with the exception of essential basic services, to stop the spread of COVID-19. Read More

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http://dx.doi.org/10.1186/s13063-020-04494-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322707PMC

Low sensitivity of histopathological examination of peri-implant tissue samples in diagnosing postoperative spinal implant infection.

Bone Joint J 2020 Jul;102-B(7):899-903

Charité - Universitätsmedizin Berlin, Berlin, Germany.

Aims: To evaluate the histopathological examination of peri-implant tissue samples as a technique in the diagnosis of postoperative spinal implant infection (PSII).

Methods: This was a retrospective analysis. Patients who underwent revision spinal surgery at our institution were recruited for this study. Read More

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http://dx.doi.org/10.1302/0301-620X.102B7.BJJ-2019-1725.R2DOI Listing

Atypical spinal tuberculosis mimicking malignancy: the utility of multimodality imaging evaluation.

Postgrad Med J 2020 Jun 28. Epub 2020 Jun 28.

Department of Radiology, Changi General Hospital, Singapore.

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http://dx.doi.org/10.1136/postgradmedj-2020-138350DOI Listing

Deep surgical site infection after posterior instrumented fusion for rheumatoid upper cervical subluxation treated with antibiotic-loaded bone cement: Three case reports.

Medicine (Baltimore) 2020 Jun;99(26):e20892

Department of Orthopaedic Surgery, Saitama Medical Center, Saitama Medical University, Kawagoe, Saitama, Japan.

Introduction: Patients with rheumatoid arthritis (RA) tend to be immunosuppressed due to RA itself and the therapeutic drugs administered. The management of surgical site infection (SSI) following upper cervical spinal instrumented fusion in RA patients is challenging; however, literature on the treatment for such conditions is scarce. We report 3 consecutive patients with RA, who developed deep SSI following upper cervical posterior fusion and were treated using antibiotic-loaded bone cement (ALBC). Read More

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http://dx.doi.org/10.1097/MD.0000000000020892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328963PMC

Unplanned return to operation room (OR) following growing spinal constructs (GSCs) in early onset scoliosis (EOS)-a multi-centric study.

Eur Spine J 2020 Jun 25. Epub 2020 Jun 25.

Primus Super-Speciality Hospital, Chandragupta Marg, Chanakyapuri, New Delhi, 110 021, India.

Purpose: To evaluate the incidence and risk factors associated with the unplanned return to OR in EOS.

Methods: Medical records of 51 patients of EOS operated at three different centres using various types of GSCs were evaluated for complications requiring unplanned surgeries. Data were analysed to find out rate of unplanned surgeries in relation to the aetiology, age and Cobb angle at index surgery, type of implant, cause of unplanned surgery, and management required. Read More

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http://dx.doi.org/10.1007/s00586-020-06506-4DOI Listing

Auxiliary role of mesenchymal stem cells as regenerative medicine soldiers to attenuate inflammatory processes of severe acute respiratory infections caused by COVID-19.

Cell Tissue Bank 2020 Jun 25. Epub 2020 Jun 25.

Metabolomics and Genomics Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

Acute respiratory infections as one of the most common problems of healthcare systems also can be considered as an important reason for worldwide morbidity and mortality from infectious diseases. Coronaviruses are a group of well-known respiratory viruses that can cause acute respiratory infections. At the current state, the 2019 novel coronavirus is cited as the most worldwide problematic agent for the respiratory system. Read More

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http://dx.doi.org/10.1007/s10561-020-09842-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315014PMC

Rabbit model of implant-associated spinal infection.

Dis Model Mech 2020 Jul 8. Epub 2020 Jul 8.

Division of Infectious Diseases, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland

Post-surgical implant-associated spinal infection is a devastating complication commonly caused by Biofilm formation is thought to reduce penetration of antibiotics and immune cells, contributing to chronic and difficult-to-treat infections. A rabbit model of a posterior-approach spinal surgery was created, in which bilateral titanium pedicle screws were inter-connected by a plate at the level of L6 and inoculated with a methicillin-resistant (MRSA) bioluminescent strain. whole animal bioluminescence imaging (BLI) and bacterial cultures demonstrated a peak in bacterial burden by day 14, when wound dehiscence occurred. Read More

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http://dx.doi.org/10.1242/dmm.045385DOI Listing

A prospective, randomized, controlled study assessing vagus nerve stimulation using the gammaCore®-Sapphire device for patients with moderate to severe CoViD-19 Respiratory Symptoms (SAVIOR): A structured summary of a study protocol for a randomised controlled trial".

Trials 2020 Jun 26;21(1):576. Epub 2020 Jun 26.

Hospital Clínico Universitario de Valencia, Anaesthesia, Critical Care and Pain Management Unit, Valencia, Spain.

Objectives: Primary Objective: The primary objective is to reduce initiation of mechanical ventilator dependency in patients with moderate to severe CoViD- 19. This will be measured as the difference between the control group and active group for subjects admitted to the hospital for CoViD-19. Secondary Objectives: • To evaluate cytokine trends / Prevent cytokine storms • To evaluate supplemental oxygen requirements • To decrease mortality of CoViD-19 patients • Delay onset of ventilation TRIAL DESIGN: The study is a single centre, 2-arm, prospective, randomized (ratio 1:1), controlled trial with parallel groups design to compare the reduction of respiratory distress in a CoViD-19 population, using the intervention of the gammaCore®-Sapphire device plus standard of care (active) vs. Read More

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http://dx.doi.org/10.1186/s13063-020-04486-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316576PMC

Parvimonas micra as a rare cause of spondylodiscitis - case series from a single centre.

Swiss Med Wkly 2020 Jun 16;150:w20272. Epub 2020 Jun 16.

Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, Switzerland.

Background: The anaerobe Parvimonas micra is usually recovered as part of the normal flora or in polymicrobial infections of odontogenic or gastrointestinal origin. P. micra has rarely been described as the causative organism of pyogenic spondylodiscitis. Read More

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http://dx.doi.org/10.4414/smw.2020.20272DOI Listing

[The effectiveness of local application of vancomycin powder in the prevention of surgical site infections in spine surgery: a meta-analysis].

Khirurgiia (Mosk) 2020 (6):60-70

Irkutsk State Medical University of the Ministry of Health of Russia, Irkutsk, Russia.

Objective: To perform a meta-analysis of studies examining the effectiveness of the local application of vancomycin powder for the prophylaxis of surgical site infections (SSIs) in spine surgery.

Material And Methods: Retrospective cohort studies and prospective randomized clinical trials were searched for in the Pubmed, EMBASE, Cochrane Library and eLibrary databases published from 2008 to December 2018. For the resulting variables, the odds ratio and 95% confidence interval were calculated using random and fixed effects models. Read More

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http://dx.doi.org/10.17116/hirurgia202006160DOI Listing

Biological basis of child health 4: an overview of the central nervous system and principles of neurological assessment.

Authors:
Doreen Crawford

Nurs Child Young People 2020 Jun 22. Epub 2020 Jun 22.

Crawford-McKenzie, Colsterworth, Lincolnshire, England.

This article is the fourth in a series on the biological basis of child health. It explains the embryological development of the nervous system and describes some of the anatomical and physiological features of the central nervous system, which is comprised of the brain and spinal cord. It also outlines the principles of neurological assessment in infants and children, before detailing the presentation and management of three conditions that can affect the central nervous system in this patient population - seizures, meningitis and raised intracranial pressure. Read More

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http://dx.doi.org/10.7748/ncyp.2020.e1249DOI Listing

Risk factors for academic difficulties in children with myelin oligodendrocyte glycoprotein antibody-associated acute demyelinating syndromes.

Dev Med Child Neurol 2020 Jun 22. Epub 2020 Jun 22.

National Referral Center for Rare Inflammatory Brain and Spinal Diseases, Le Kremlin-Bicêtre, France.

Aim: To describe cognitive abilities through the evaluation of academic difficulties in children with acute demyelinating syndromes (ADS) and myelin oligodendrocyte glycoprotein (MOG) antibodies.

Method: This was an observational, retrospective study of a French paediatric cohort that included children aged 18 years and younger. Clinical, biological, and imaging data were collected and academic outcome was measured. Read More

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http://dx.doi.org/10.1111/dmcn.14594DOI Listing

Neurourological assessment in people with multiple sclerosis (MS): a new evaluated algorithm.

Mult Scler Relat Disord 2020 May 30;44:102248. Epub 2020 May 30.

Coloplast GmbH, Kuehnstraße 75, 22045 Hamburg, Germany. Electronic address:

Background: Neurogenic lower urinary tract dysfunction (NULTD) is common in patients with multiple sclerosis (MS); nevertheless, it is often underestimated, underdiagnosed, and undertreated due to patients' sense of shame, variability of symptoms, as well as lack of communication between neurologists and urologists, despite the availability of several guidelines based on scientific evidence and expert opinion.

Objective: This study was conducted to develop an easy-to-perform algorithm for diagnosing neurogenic lower urinary tract disease in patients with MS for daily neurological and urological routine, including the identification of red flags.

Methods: In consensus group meetings, interprofessional experts (neurologists, urologists, neurourologists, nurses, nurse practitioners, occupational therapists, physical therapists as well as representatives of national MS centers, self-care groups, social care, residential care, and health-aid-providers) developed a diagnostic algorithm to detect NULTD in patients with MS. Read More

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http://dx.doi.org/10.1016/j.msard.2020.102248DOI Listing

Epidemiology of skeletal tuberculosis in Beijing, China: a 10-year retrospective analysis of data.

Eur J Clin Microbiol Infect Dis 2020 Jun 19. Epub 2020 Jun 19.

National Clinical Laboratory on Tuberculosis, Beijing Chest Hospital, Capital Medical University/Beijing Tuberculosis & Thoracic Tumor Research Institute, No 9, Beiguan Street, Tongzhou District, Beijing, 101149, People's Republic of China.

Skeletal tuberculosis (STB) is one of the most common forms of extrapulmonary tuberculosis; however, limited epidemiological data are available on this public health concern worldwide, especially in developing countries. The aims of this study were to analyze the epidemiological characteristics of STB cases and to identify risk factors associated with drug resistance among STB cases in China. We included STB inpatients at Beijing Chest Hospital from January 2009 through December 2018. Read More

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http://dx.doi.org/10.1007/s10096-020-03924-6DOI Listing

Involuntary ambulatory triage during the COVID-19 pandemic - A neurosurgical perspective.

PLoS One 2020 18;15(6):e0234956. Epub 2020 Jun 18.

Department of Neurosurgery, University Medical Center of the Johannes Gutenberg-University, Mainz, Rhineland Palatinate, Germany.

Background: The coronavirus disease 2019 (COVID-19) pandemic poses an unprecedented challenge to health-care systems around the world. As approximately one-third of the world´s population is living under "lockdown" conditions, medical resources are being reallocated and hospital admissions are limited to emergencies. We examined the decision-making impact of these actions and their effects on access to hospital treatment in patients with neurosurgical conditions. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0234956PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302699PMC

Immediate plastic surgery closure at index spinal surgery minimizes complications compared to delayed reconstruction: A retrospective cohort review.

J Plast Reconstr Aesthet Surg 2019 Dec 16. Epub 2019 Dec 16.

Division of Plastic Surgery, Department of Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA, United States.

Background: Complex spine surgery in patients with major comorbidities leads to increased need for midline back wound reconstruction by plastic surgeons. Literature suggests that back wound reconstruction concurrent with high-risk immediate/index spine surgery may lead to fewer complication. This study aimed to validate this claim in a large cohort treated at a tertiary center. Read More

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http://dx.doi.org/10.1016/j.bjps.2019.11.008DOI Listing
December 2019

Erythropoietin as candidate for supportive treatment of severe COVID-19.

Mol Med 2020 06 16;26(1):58. Epub 2020 Jun 16.

Psychiatric Centre Copenhagen, University Hospital, Rigshospitalet, Copenhagen, Denmark.

In light of the present therapeutic situation in COVID-19, any measure to improve course and outcome of seriously affected individuals is of utmost importance. We recap here evidence that supports the use of human recombinant erythropoietin (EPO) for ameliorating course and outcome of seriously ill COVID-19 patients. This brief expert review grounds on available subject-relevant literature searched until May 14, 2020, including Medline, Google Scholar, and preprint servers. Read More

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http://dx.doi.org/10.1186/s10020-020-00186-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297268PMC

Transitioning a Practice to Robotic Total Knee Arthroplasty Is Correlated with Favorable Short-Term Clinical Outcomes-A Single Surgeon Experience.

J Knee Surg 2020 Jun 16. Epub 2020 Jun 16.

Department of Orthopaedic Surgery, NorthShore University Orthopaedic and Spine Institiute, Skokie, Illinois.

Background:  This study sought to evaluate the patient experience and short-term clinical outcomes associated with the hospital stay of patients who underwent robotic arm-assisted total knee arthroplasty (TKA). These results were compared with a cohort of patients who underwent TKA without robotic assistance performed by the same surgeon prior to the introduction of this technology.

Materials And Methods:  A cohort of consecutive patients undergoing primary TKA for the diagnosis of osteoarthritis by a single fellowship trained orthopaedic surgeon over a 39-month period was identified. Read More

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http://dx.doi.org/10.1055/s-0040-1712984DOI Listing

Effects of Pseudoloma neurophilia infection on the brain transcriptome in zebrafish (Danio rerio).

J Fish Dis 2020 Jun 15. Epub 2020 Jun 15.

Faculty of Veterinary Medicine, Department of Paraclinical Sciences, Norwegian University of Life Sciences, Oslo, Norway.

Laboratory zebrafish are commonly infected with the intracellular, brain-infecting microsporidian parasite Pseudoloma neurophilia. Chronic P. neurophilia infections induce inflammation in meninges, brain and spinal cord, and have been suggested to affect neural functions since parasite clusters reside inside neurons. Read More

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http://dx.doi.org/10.1111/jfd.13198DOI Listing

Utility of the Hospital Frailty Risk Score for Predicting Adverse Outcomes in Degenerative Spine Surgery Cohorts.

Neurosurgery 2020 Jun 15. Epub 2020 Jun 15.

Department of Anesthesiology, Perioperative and Pain Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.

Background: As spine surgery becomes increasingly common in the elderly, frailty has been used to risk stratify these patients. The Hospital Frailty Risk Score (HFRS) is a novel method of assessing frailty using International Classification of Diseases, Tenth Revision (ICD-10) codes. However, HFRS utility has not been evaluated in spinal surgery. Read More

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http://dx.doi.org/10.1093/neuros/nyaa248DOI Listing

Interbody fusion in degenerative lumbar spinal stenosis with additional posterolateral fusion using Escherichia coli-derived bone morphogenetic protein-2: A Pilot study.

Medicine (Baltimore) 2020 Jun;99(24):e20477

Department of Orthopedic Surgery, Hanyang University College of Medicine, Seoul, Republic of Korea.

This case series investigated the efficacy and optimal dose of Escherichia coli-derived bone morphogenetic protein-2 (E.BMP-2) as a bone graft substitute for additional posterolateral spinal fusion, accompanying interbody fusion procedures, for treating lumbar degenerative spinal stenosis. This study focused on the optimal dose for each segment and the efficacy of E. Read More

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http://dx.doi.org/10.1097/MD.0000000000020477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302626PMC

Management of Fever in Infants and Young Children.

Am Fam Physician 2020 06;101(12):721-729

Drexel University College of Medicine, Philadelphia, PA, USA.

Despite dramatic reductions in the rates of bacteremia and meningitis since the 1980s, febrile illness in children younger than 36 months continues to be a concern with potentially serious consequences. Factors that suggest serious infection include age younger than one month, poor arousability, petechial rash, delayed capillary refill, increased respiratory effort, and overall physician assessment. Urinary tract infections are the most common serious bacterial infection in children younger than three years, so evaluation for such infections should be performed in those with unexplained fever. Read More

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Long-term Outcomes of Patients With Fungal Infections Associated With Contaminated Methylprednisolone Injections.

Open Forum Infect Dis 2020 Jun 9;7(6):ofaa164. Epub 2020 May 9.

Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Background: The largest health care-associated infection outbreak in the United States occurred during 2012-2013. Following injection of contaminated methylprednisolone, 753 patients developed infection with a dematiaceous mold, . The long-term outcomes of these infections have not been described. Read More

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http://dx.doi.org/10.1093/ofid/ofaa164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275232PMC

Spine Surgery Supported by Augmented Reality.

Global Spine J 2020 Apr 28;10(2 Suppl):41S-55S. Epub 2020 May 28.

Department of Neurosurgery, University Marburg, Marburg, Germany.

Study Design: A prospective, case-based, observational study.

Objectives: To investigate how microscope-based augmented reality (AR) support can be utilized in various types of spine surgery.

Methods: In 42 spinal procedures (12 intra- and 8 extradural tumors, 7 other intradural lesions, 11 degenerative cases, 2 infections, and 2 deformities) AR was implemented using operating microscope head-up displays (HUDs). Read More

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http://dx.doi.org/10.1177/2192568219868217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263340PMC

Successful Anesthetic Management in Cesarean Section for Pregnant Woman with COVID-19.

Am J Case Rep 2020 Jun 12;21:e925512. Epub 2020 Jun 12.

King Abdullah University Hospital, Irbid, Jordan.

BACKGROUND The current COVID-19 pandemic highlights the importance of the mindful use of financial and human resources. Preventing infections and preserving resources and manpower are crucial in healthcare. It is important to ensure the ability of surgeons and specialized interventionalists to function through the pandemic. Read More

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http://dx.doi.org/10.12659/AJCR.925512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307933PMC

Misinformation about spinal manipulation and boosting immunity: an analysis of Twitter activity during the COVID-19 crisis.

Chiropr Man Therap 2020 9;28:34. Epub 2020 Jun 9.

Department of Chiropractic Medicine, Balgrist University Hospital, University of Zurich, Zürich, Switzerland.

Background: Social media has become an increasingly important tool in monitoring the onset and spread of infectious diseases globally as well monitoring the spread of information about those diseases. This includes the spread of misinformation, which has been documented within the context of the emerging COVID-19 crisis. Understanding the creation, spread and uptake of social media misinformation is of critical importance to public safety. Read More

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http://dx.doi.org/10.1186/s12998-020-00319-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281697PMC

Minimally Invasive Spine Lumbar Surgery in Obese Patients: A Systematic Review and Meta-Analysis.

HSS J 2020 Jul 18;16(2):168-176. Epub 2020 Jan 18.

Hospital for Special Surgery, 535 E. 70th St., New York, NY USA.

Background: Transforaminal lumbar interbody fusion (TLIF) is the treatment of choice for lumbar spinal stenosis and spondylolisthesis. The procedure can be performed through a traditional open approach (O-TLIF) or through minimally invasive techniques (MI-TLIF). Spinal surgeries in obese patients can pose risks, including increased rates of infection and thromboembolic events. Read More

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http://dx.doi.org/10.1007/s11420-019-09735-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253546PMC

Misinformation about spinal manipulation and boosting immunity: an analysis of Twitter activity during the COVID-19 crisis.

Chiropr Man Therap 2020 06 9;28(1):34. Epub 2020 Jun 9.

Department of Chiropractic Medicine, Balgrist University Hospital, University of Zurich, Zürich, Switzerland.

Background: Social media has become an increasingly important tool in monitoring the onset and spread of infectious diseases globally as well monitoring the spread of information about those diseases. This includes the spread of misinformation, which has been documented within the context of the emerging COVID-19 crisis. Understanding the creation, spread and uptake of social media misinformation is of critical importance to public safety. Read More

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http://dx.doi.org/10.1186/s12998-020-00319-4DOI Listing

On when guidelines conflict: Patient safety, quality of life and CAUTI reduction in patients with spinal cord injury.

Authors:
John P Lavelle

Spinal Cord Ser Cases 2019 06 10;5(1):57. Epub 2019 Jun 10.

Veterans Affairs Palo Alto Health Care System, Urology Section (112), 3801 Miranda Ave, Palo Alto, CA, 94304, USA.

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http://dx.doi.org/10.1038/s41394-019-0199-3DOI Listing

When guidelines conflict: patient safety, quality of life, and CAUTI reduction in patients with spinal cord injury.

Authors:
Matthew Davis

Spinal Cord Ser Cases 2019 06 10;5(1):56. Epub 2019 Jun 10.

McGovern Medical School, Physical Medicine & Rehabilitation, Houston, TX, USA.

The current Medicare payment structure and some of the recent guidelines aimed at reducing catheter-associated urinary tract infections may be generating a financial incentive for the protocolized, systematic removal of indwelling catheters in hospitalized patients-including those with spinal cord injury. This creates a tension with the Consortium for Spinal Cord Medicine's clinical practice guidelines for the management of neurogenic bladder. This article presents a series of cases and a discussion of the implications with regard to patient safety and quality of life. Read More

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http://dx.doi.org/10.1038/s41394-019-0198-4DOI Listing

Disseminated septic arthritis caused by infection.

BMJ Case Rep 2020 Jun 7;13(6). Epub 2020 Jun 7.

Department of Infectious Diseases, Leeds Teaching Hospitals NHS Trust, Leeds, UK.

We describe a rare case of bloodstream infection and disseminated septic arthritis in a relatively fit and well 73-year-old retired farmer and gamekeeper, due to the zoonotic organism The presence of the organism in multiple joints led to slow clinical response to treatment and was complicated by relapse of infection and lengthy disability. Source control was achieved with multiple joint washouts and spinal cord decompression. Following this, a 6-week course of intravenous antibiotics was required for complete clearance of infection. Read More

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http://dx.doi.org/10.1136/bcr-2019-234188DOI Listing

The Saudi Spine Society guidelines on spinal surgery during the COVID-19 pandemic.

J Orthop Surg Res 2020 Jun 8;15(1):211. Epub 2020 Jun 8.

Department of Orthopaedic Surgery, University of Western Ontario, London Health Sciences Center, London, ON, Canada.

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http://dx.doi.org/10.1186/s13018-020-01732-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278250PMC

[Minimal invasive surgery-transforaminal lumbar interbody fusion combined with expanded pedicle screw through Mast Quadrant channel for the treatment of senile pyogenic discitis and vertebral osteomyelitis].

Zhongguo Gu Shang 2019 Oct;32(10):937-940

Department of Orthopaedics, the People's Hospital of Gansu, Lanzhou 730000, Gansu, China;

Objective: To investigate the feasibility and clinical efficacy of minimal invasive surgery-transforaminal lumbar interbody fusion (MIS-TLIF) combined with expanded pedicle screw (EPS) in the treatment of elderly patients with pyogenic discitis and vertebral osteomyelitis (PDVO).

Methods: The clinical data of 11 elderly patients with pyogenic discitis and vertebral osteomyelitis treated from January 2016 to June 2017 were retrospectively analyzed, including 7 males and 4 females, aged from 59 to 79 years old with an average of (68.09±5. Read More

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http://dx.doi.org/10.3969/j.issn.1003-0034.2019.10.013DOI Listing
October 2019

[Application value of immature granulocyte count in predicting early infection after spinal operation].

Zhongguo Gu Shang 2019 Oct;32(10):898-903

Department of Trauma and Orthopaedics, Yuncheng Central Hospital, Yuncheng 044000, Shanxi, China;

Objective: To evaluate the early predictive value of immature granulocytes(IGs) in postoperative infection in patients with spinal injury.

Methods: The clinical data of 78 patients with spinal cord injury underwent surgery from October 2016 to October 2018 were collected. There were 57 males and 21 females, aged from 45 to 63 years old with an average of (55. Read More

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http://dx.doi.org/10.3969/j.issn.1003-0034.2019.10.005DOI Listing
October 2019

[Surgical treatment of deep infection around the spine].

Zhongguo Gu Shang 2019 Oct;32(10):886-891

Department of Orthopaedics, Tongde Hospital of Zhejiang Province, Hangzhou 310012, Zhejiang, China;

Objective: To study the surgical method and clinical effect of deep infection around the spine.

Methods: The clinical data of 7 patients with deep infections around the spine treated from January 2015 to January 2018 were retrospectively analyzed. All patients were acute infection within 3 weeks after spinal surgery. Read More

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http://dx.doi.org/10.3969/j.issn.1003-0034.2019.10.003DOI Listing
October 2019

[Analysis of risk factors of postoperative wound infection in lumbar spondylolisthesis].

Zhongguo Gu Shang 2019 Oct;32(10):882-885

Department of Orthopaedics, Zhejiang Hospital, Hangzhou 310000, Zhejiang, China;

Objective: To explore related risk factors of postoperative wound infection in lumbar spondylolisthesis.

Methods: The clinical data of 296 patients with lumbar spondylolisthesis underwent posterior decompression and fusion from January 2013 to December 2017 were retrospectively analyzed. According to whether the wound was infected or not, the patients were divided into infection group and non-infection group. Read More

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http://dx.doi.org/10.3969/j.issn.1003-0034.2019.10.002DOI Listing
October 2019

[Analysis of early diagnosis, treatment and the risk factors for surgical site infection in spinal surgery].

Zhongguo Gu Shang 2019 10;32(10):879-881

Department of Orthopaedics, the Sixth Medical Center of PLA General Hospital, Beijing 100048, China.

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http://dx.doi.org/10.3969/j.issn.1003-0034.2019.10.001DOI Listing
October 2019

The Effect of Beta-lactam Allergy Status on the Rate of Surgical Site Infections: A Retrospective Cohort Study.

Ann Surg 2020 Jun 3. Epub 2020 Jun 3.

Pharmacy Department, Aultman Hospital, Canton, OH 44710.

Objective: To determine if patients with reported BL allergies have increased odds of developing SSI compared to reported NBL allergic patients.

Summary Of Background Data: SSI represent a significant risk of morbidity and mortality for patients. Cefazolin-based perioperative antibiotic prophylaxis is the guideline-recommended drug-of-choice for most procedures. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003949DOI Listing

Clinical characteristics of two human-to-human transmitted coronaviruses: Corona Virus Disease 2019 vs. Middle East Respiratory Syndrome Coronavirus.

Authors:
P Xu G-D Sun Z-Z Li

Eur Rev Med Pharmacol Sci 2020 05;24(10):5797-5809

Department of Spinal Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, People's Republic of China.

Objective: Subsequent to a global outbreak of the Middle East Respiratory Syndrome (MERS) in 2012, a novel human coronavirus, known as Corona Virus Disease 2019 (COVID-19) has caused a major disease outbreak. The aim of this study was to perform a systematic review to compare epidemiological, clinical, and laboratory features of COVID-19 and MERS-COV populations.

Materials And Methods: We searched PubMed, EMBASE, and Cochrane Central Register of Controlled Trials database to identify potential studies that have reported COVID-19 or MERS-COV disease. Read More

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http://dx.doi.org/10.26355/eurrev_202005_21374DOI Listing

Acute disseminated encephalomyelitis after SARS-CoV-2 infection.

Neurol Neuroimmunol Neuroinflamm 2020 09 1;7(5). Epub 2020 Jun 1.

From the Department of Neuroscience (G.N., E.P., D.F.), Ospedale Policlinico San Martino, IRCCS; Ospedale Policlinico San Martino (T.R., L.R., M.I.), IRCCS; Department of Neuroradiology (L.S., C.R.), Ospedale Policlinico San Martino, IRCCS, Genova, Italy; Department of Health Sciences (DISSAL) (L.R.), University of Genova; and Department of Neuroscience (M.I.), Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI) and Center of Excellence for Biomedical Research (CEBR), University of Genova, Italy.

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http://dx.doi.org/10.1212/NXI.0000000000000797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286650PMC
September 2020

Immediate Voice and Swallowing Complaints Following Revision Anterior Cervical Spine Surgery.

Otolaryngol Head Neck Surg 2020 Jun 2:194599820926133. Epub 2020 Jun 2.

Department of Otolaryngology-Head and Neck Surgery, University of California-San Francisco, San Francisco, California, USA.

Objective: To report on the incidence of dysphagia, dysphonia, and acute vocal fold motion impairment (VFMI) following revision anterior cervical spine surgery, as well as to identify risk factors associated with acute VFMI in the immediate postoperative period.

Study Design: Retrospective cohort study.

Setting: Tertiary care center. Read More

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http://dx.doi.org/10.1177/0194599820926133DOI Listing

Transforaminal debridement with a posterior-only approach involving placement of an interbody bone graft combined with diseased vertebral fixation for the treatment of thoracic and lumbar tuberculosis: Minimum 5-year follow-up.

Medicine (Baltimore) 2020 May;99(22):e20359

Department of Orthopedics, The Third Affiliated Hospital of Chongqing Medical University (Gener Hospital), Chongqing.

The aim of this study was to evaluate the clinical and imaging results of transforaminal debridement with a posterior-only approach involving placement of an interbody bone graft combined with diseased vertebral fixation for the treatment of thoracic and lumbar tuberculosis (TB) with a minimum 5-year follow-up.Sixty-five patients who presented with active thoracic and lumbar TB between October 2006 and August 2013 were retrospectively analyzed: 20 were thoracic TB (group A), 17 were thoracolumbar TB (group B), and 28 were lumbar TB (group C). The patient data, operating time, blood loss, Visual Analog Scale score, Oswestry Disability Index score, correction of kyphosis, recovery of neurological function, and complications were recorded and analyzed. Read More

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http://dx.doi.org/10.1097/MD.0000000000020359DOI Listing
May 2020
5.723 Impact Factor

Vertebral tuberculosis as a paradoxical reaction to the treatment of pulmonary and meningeal tuberculosis in an immunocompetent patient: A case report.

Medicine (Baltimore) 2020 May;99(21):e20012

School of Medicine at Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.

Introduction: Paradoxical reaction in tuberculosis (TB) is defined as the reappearance of general symptoms, aggravation of pre-existing diseases, or appearance of new lesions despite adequate anti-TB therapy. It may result from the hyperactivity of the immune response, resulting in an intense inflammation. There are few cases of vertebral TB reported as paradoxical reaction, mainly among immunocompetents patients. Read More

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http://dx.doi.org/10.1097/MD.0000000000020012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249907PMC

Association between pressure ulcers and the risk of postoperative infections in male adults with spinal cord injury.

Br J Neurosurg 2020 Jun 1:1-4. Epub 2020 Jun 1.

Department of Orthopaedics, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.

Data about postoperative infections in male adults with spinal cord injury are scarce. We aimed to evaluate the association between prior exposure to pressure ulcers (PU) and the risk of postoperative infections in male adults with spinal cord injury (SCI). We conducted a prospective study of male adults receiving surgery of SCI from January 2007 to December 2019. Read More

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http://dx.doi.org/10.1080/02688697.2020.1769552DOI Listing

Syringomyelia as a delayed complication of lumbar-sacral adhesive arachnoiditis in Pott's disease.

BMJ Case Rep 2020 May 27;13(5). Epub 2020 May 27.

Department of General Medicine, Government Medical College and Hospital, Chandigarh, India.

Syringomyelia is the development of a fluid-filled cyst (syrinx) within the spinal cord and is an extremely rare chronic manifestation of tuberculosis. The syrinx so formed may expand over time, causing compression or destruction of spinal tracts and surrounding nerve roots. Development of syringomyelia in a patient of Pott's disease is particularly infrequent. Read More

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http://dx.doi.org/10.1136/bcr-2019-234032DOI Listing

A new sequential animal model for infection-related non-unions with segmental bone defect.

BMC Musculoskelet Disord 2020 May 27;21(1):329. Epub 2020 May 27.

Unfallklinik Ludwigshafen, Klinik für Unfallchirurgie und Orthopädie, Ludwig-Guttmann-Strasse 13, 67071, Ludwigshafen, Germany.

Background: The treatment of fracture-related infections (FRI) is still a challenge for orthopedic surgeons. The prevalence of FRI is particularly high in open fractures with extensive soft-tissue damage. This study aimed to develop a new two-step animal model for non-unions with segmental bone defects, which could be used to evaluate new innovative bone substitutes to improve the therapeutic options in humans with FRI and bone defects. Read More

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http://dx.doi.org/10.1186/s12891-020-03355-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254709PMC