728 results match your criteria Spinal Imaging in Astrocytoma


Intramedullary Masses of the Spinal Cord: Radiologic-Pathologic Correlation.

Radiographics 2020 Jul-Aug;40(4):1125-1145. Epub 2020 Jun 12.

From the Department of Radiology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD 20814 (R.Y.S.); and Department of Radiology, Mayo Clinic, Rochester, Minn (K.K.K.).

Spinal cord tumors are a challenge for patients and neurosurgeons because of the high risk of neurologic deficits from the disease process and surgical interventions. Spinal cord tumors are uncommon, and approximately 2%-3% of primary intra-axial tumors of the central nervous system occur in the spinal cord. Primary intra-axial tumors are usually derived from neuroepithelial tissue, especially glial cells. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1148/rg.2020190196DOI Listing

Exploring the Feasibility and Effects of a Ketogenic Diet in Patients With CNS Malignancies: A Retrospective Case Series.

Front Neurosci 2020 19;14:390. Epub 2020 May 19.

Cedars-Sinai Medical Center, Samuel Oschin Comprehensive Cancer Center, Los Angeles, CA, United States.

Recently, the ketogenic diet has been proposed as an adjunct treatment for a range of medical conditions including weight loss, diabetes, cancer, and neurodegenerative diseases. Because malignant CNS tumors are highly dependent on glucose, the use of a ketogenic diet as an adjunct therapy is currently being explored. This case series summarizes our experience implementing a ketogenic diet for patients with CNS malignancies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fnins.2020.00390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248360PMC

Fluorescein-guided surgery for spinal gliomas: Analysis of 220 consecutive cases.

Int Rev Neurobiol 2020 13;151:139-154. Epub 2020 May 13.

Department of Neurosurgery, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China. Electronic address:

Objective: Sodium fluorescein (FL) is widely used as a fluorescent tracer for brain tumor resection. However, FL-guided resection of spinal gliomas has been reported only occasionally. To evaluate the safety, characteristics, and usefulness of FL-guided surgery in the resection of spinal glioma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/bs.irn.2020.03.004DOI Listing

Unexpected discovery of a diffuse astrocytoma of the conus medullaris in an elderly NF1 patient.

Radiol Case Rep 2020 Jun 18;15(6):784-788. Epub 2020 Apr 18.

Department of Radiology, Toho University Sakura Medical Center.

Neurofibromatosis type 1 (NF1) is one of the most common genetic neurocutaneous disorders, and it is well known to be associated with peripheral or central nervous system malignancies. The most common malignant tumors are malignant peripheral nerve sheath tumors (MPNSTs); MPNSTs are the most common cause of death in patients with NF1. Central nervous system malignancies rarely occur. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.radcr.2020.02.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7167499PMC

Novel Use of Subcostal Polyethylene Bands to Manage Tumor-Related Scoliosis Requiring Serial Imaging: A Case Report.

JBJS Case Connect 2020 Jan-Mar;10(1):e0351

Departments of Orthopaedic Surgery and Neurosurgery, Shriners Hospitals for Children-Philadelphia, Philadelphia, Pennsylvania.

Case: A 16-year-old male patient with severe kyphoscoliosis, paraplegia, and neurogenic bowel/bladder caused by a juvenile pilocytic astrocytoma was treated surgically using a hybrid fusion construct with polyethylene bands after neoplasm resection. Owing to the necessity of serial postoperative magnetic resonance imaging studies to evaluate the recurrence of pathology and known effect of metal artifact from spinal instrumentation, preservation of radiographic resolution was critical.

Conclusion: We describe the novel utility of polyethylene bands placed around the ribs as a safe and effective form of hybrid construct for reducing radiographic metal artifact in spinal deformity cases requiring serial imaging. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2106/JBJS.CC.19.00351DOI Listing

Surgical Management of Intramedullary Spinal Cord Tumors.

Neurosurg Clin N Am 2020 Apr 31;31(2):237-249. Epub 2020 Jan 31.

Department of Neurological Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA; Department of Neurological Surgery, Weill Cornell Medical College, 525 E. 68th St, New York, NY 10065, USA.

Intramedullary spinal cord tumors (IMSCT) comprise a rare subset of CNS tumors that have distinct management strategies based on histopathology. These tumors often present challenges in regards to optimal timing for surgery, invasiveness, and recurrence. Advances in microsurgical techniques and technological adjuncts have improved extent of resection and outcomes with IMSCT. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nec.2019.12.004DOI Listing

Spinal cord anaplastic astrocytoma with BRAF V600E mutation: A case report and review of literature.

Neuropathology 2020 Jun 27;40(3):275-279. Epub 2020 Jan 27.

Department of Neurosurgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

A 17-year-old female complained of lower extremity pain that progressed to low back pain accompanied by paraparesis. Magnetic resonance imaging revealed a mass in the conus medullaris of the spinal cord at the thoracic spine 11-12 level. The patient underwent resection of the mass. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/neup.12636DOI Listing

Angiocentric glioma: Drop Metastases to the Spinal Cord.

World Neurosurg 2020 Apr 14;136:110-116. Epub 2020 Jan 14.

Department of Neurosurgery, National Neurosurgical Centre, Beaumont Hospital, Dublin, Ireland.

Background: Angiocentric glioma (AG) is an epileptogenic low grade (World Health Organization grade I) glial tumor with astrocytic and ependymal differentiation, most commonly affecting the pediatric and adolescent population. Despite its infiltrating histological growth kinetics, it is widely accepted that AG has a low potential for aggressive behavior.

Case Description: We present the case of a 42-year-old man who represents the first documented case of not only extracranial manifestation of AG, but also spinal metastatic dissemination. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2020.01.037DOI Listing

Thoracolumbar pilomyxoid astrocytoma concomitant with spinal scoliosis: A case report and literature review.

Surg Neurol Int 2019 6;10:235. Epub 2019 Dec 6.

Department of Neurosurgery, Iran University of Medical Sciences, Tehran, Iran.

Background: Pilomyxoid astrocytoma (PMA) is a variant of pilocytic astrocytomas but exhibits more aggressive behavior. Further, it is more prevalent in the hypothalamic/chiasmatic regions and is only rarely encountered in the thoracic spine.

Case Description: A 9-year-old male presented with severe spastic paraparesis (motor/sensory) attributed to a thoracic cord PMA and scoliosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.25259/SNI_548_2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911671PMC
December 2019

Extracranial Metastases From Glioblastoma With Primitive Neuronal Components on FDG PET/CT.

Clin Nucl Med 2020 Mar;45(3):e162-e164

From the Departments of Medical Imaging.

A 17-year-old girl with World Health Organization grade IV glioblastoma with primitive neuronal components (histone H3 G34-mutant and IDH1 wild type) underwent whole-body FDG PET/CT staging due to vertebral metastases on initial MRI. PET/CT revealed extracranial metastatic disease with spinal leptomeningeal dissemination, osseous metastases, and peritoneal seeding via a ventriculoperitoneal shunt. Glioblastoma is uncommon in pediatric patients and particularly those with primitive neuronal components. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/RLU.0000000000002896DOI Listing

Spinal rosette-forming glioneuronal tumor: A case report.

Medicine (Baltimore) 2019 Dec;98(49):e18271

Department of Cancer Pathology, Hokkaido University Faculty of Medicine, Sapporo, Japan.

Rationale: Rosette-forming glioneuronal tumor (RGNT) is a rare tumor which has been first reported as the fourth ventricle tumor by Komori et al and is classified as a distinct clinicopathological entity by the WHO Classification of Tumors of the Central Nervous System as in 2007. Although RGNTs were reported to occur in both supratentorial and inflatentorial sites, only 4 case reports of spinal RGNT have been demonstrated.

Patient Concerns: A 37-year-old female presenting with slowly progressing right-sided clumsiness. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000018271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6919525PMC
December 2019
5 Reads

Role of Diffusion Tensor Imaging Parameters in the Characterization and Differentiation of Infiltrating and Non-Infiltrating Spinal Cord Tumors : Preliminary Study.

Clin Neuroradiol 2019 Nov 21. Epub 2019 Nov 21.

2nd Department of Clinical Radiology, Medical University of Warsaw, ul. Zwirki i Wigury 61, 02-091, Warsaw, Poland.

Background And Purpose: Recent attempts to utilize diffusion tensor imaging (DTI) to identify the extent of microinfiltration of a tumor in the brain have been successful. It was therefore speculated that this technique could also be useful in the spinal cord. The aim of this study was to differentiate between infiltrating and noninfiltrating intramedullary spinal tumors using DTI-derived metrics. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00062-019-00851-8DOI Listing
November 2019

FDG PET/CT and MRI in Primary Spinal Cord Glioblastoma.

Clin Nucl Med 2020 Mar;45(3):e144-e145

From the Department of Nuclear Medicine, Laboratory of Clinical Nuclear Medicine, West China Hospital of Sichuan University.

Glioblastoma is the most common primary malignant tumor of the central nervous system, most of which occur in the brain. Primary spinal cord glioblastoma is extremely rare. A 47-year-old woman presented with recurrent and progressive paresthesia and paralysis of right lower extremity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/RLU.0000000000002800DOI Listing

Prolonged survival in a patient with a cervical spine H3K27M-mutant diffuse midline glioma.

BMJ Case Rep 2019 Oct 17;12(10). Epub 2019 Oct 17.

Neurology, University of Michigan, Ann Arbor, Michigan, USA

We report a case of prolonged survival in a patient with known cervical intramedullary H3K27M-mutant diffuse midline glioma. A 39-year-old man presented for evaluation with several months of progressive upper extremity pain and weakness. MRI of the cervical spine revealed an intramedullary ring-enhancing lesion centred at C3-C4. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2019-231424DOI Listing
October 2019
2 Reads

Spinal Pilomyxoid Astrocytoma.

Pediatr Neurosurg 2019 8;54(6):399-404. Epub 2019 Oct 8.

Division of Neurosurgery, Neurosciences Department, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.

Pilomyxoid astrocytoma (PMA) is a rare brain tumour generally located in the chiasmatic-hypothalamic region. In comparison to pilocytic astrocytoma, PMA has distinct histopathological features, aggressive clinical behaviour, a high recurrence rate, and early cerebrospinal fluid dissemination. Only 14 cases of PMA have been reported in the spinal cord since its pathological description in 1999. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000502615DOI Listing
April 2020
1 Read

Primary Spinal Astrocytomas: A Literature Review.

Cureus 2019 Jul 26;11(7):e5247. Epub 2019 Jul 26.

Neurosurgery, Kaiser Permanente - Fontana Medical Center, Fontana, USA.

Primary spinal astrocytoma is a subtype of glioma, the most common spinal cord tumor found in the intradural intramedullary compartment. Spinal astrocytomas account for 6-8% of all spinal cord tumors and are primarily low grade (World Health Organization grade I (WHO I) or WHO II). They are seen in both the adult and pediatric population with the most common presenting symptoms being back pain, sensory dysfunction, or motor dysfunction. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7759/cureus.5247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759039PMC
July 2019
2 Reads

Suprasellar pleomorphic xanthoastrocytoma: A case report.

Surg Neurol Int 2019 24;10:72. Epub 2019 Apr 24.

Division of Neurosurgery, University of Arizona, Tucson, Arizona, United States.

Background: Pleomorphic xanthoastrocytoma (PXA) is a rare form of astrocytic neoplasm most commonly found in children and young adults. This neoplasm, which is classified as a Grade II tumor by the World Health Organization classification of tumors of the central nervous system, carries a relatively favorable outcome. It is usually found supratentorially in cortical regions of the cerebral hemispheres, and as such, presenting symptoms are similar to other supratentorial cortical neoplasms; with seizures being a common initial symptom. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.25259/SNI-83-2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744826PMC
April 2019
2 Reads

Microsurgical Resection of Intraspinal Benign Tumors Using Non-Expansile Tubular Access.

World Neurosurg 2020 Jan 7;133:e97-e104. Epub 2019 Sep 7.

Spine Clinic, The American-British Cowdray Medical Center I.A.P. Campus Santa Fe, Mexico City, Mexico; National Autonomous University of Mexico, Mexico City, Mexico; Regional General Hospital #25 of the National Institute of Social Security, Mexico City, Mexico; Department of Neurology, Medicine School, University of Sonora, Obregon City, Mexico. Electronic address:

Background: Intraspinal tumors are 10 to 15 times less common than brain tumors. The midline approach with extensive laminectomies represents the current gold-standard for resection, causing instability, muscle damage, and kyphosis among other well-known complications. Minimally invasive series reported their results using retractor-based systems. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2019.08.170DOI Listing
January 2020
3 Reads

An Unusual Presentation of Spinal Giant Cell Glioblastoma in a 21-Year-Old Female.

J Investig Med High Impact Case Rep 2019 Jan-Dec;7:2324709619868255

2 Kern Medical-University of California Los Angeles, Bakersfield, CA, USA.

Primary spinal cord giant cell glioblastoma multiforme of the thoracic spinal cord is a rarely-diagnosed primary spinal cord tumor in comparison to neoplasms in intracranial locations. In this article, we highlight a young adult who was diagnosed with intramedullary giant cell glioblastoma, IDH wild-type, World Health Organization grade IV/IV of the thoracic spinal cord. This case report describes the treatment approach with a postsurgical combination of radiation therapy and temozolomide, which resulted in the patient to return to her baseline of health only to later develop neurological symptoms significant for a recurrence of malignancy. Read More

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1177/2324709619868255
Publisher Site
http://dx.doi.org/10.1177/2324709619868255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689908PMC
April 2020
4 Reads

Infratentorial Glioblastoma Metastasis to Bone.

World Neurosurg 2019 Nov 26;131:90-94. Epub 2019 Jul 26.

Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA.

Background: Glioblastoma multiforme (GBM) is a rapid-growing central nervous system neoplasm. We report a case of GBM with extensive intramedullary lumbar drop metastasis and highly unusual osseous spine metastasis from a primary infratentorial GBM occurring 10 years after the initial diagnosis, which to our knowledge has not been described previously.

Case Description: This 37-year-old man presented with new-onset headaches of increasing severity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2019.07.142DOI Listing
November 2019
3 Reads

Bevacizumab in treating the cystic components of pediatric low-grade gliomas: A report of four patients.

Pediatr Blood Cancer 2019 11 26;66(11):e27917. Epub 2019 Jul 26.

The University of Rochester School of Medicine and Dentistry, Rochester, New York.

Low-grade gliomas (LGG) are among the most common types of brain tumors in children and young adults. These tumors often consist of solid and cystic components. Bevacizumab is a documented treatment for progressive LGG, yet the impact of therapy on the cystic component of these tumors is unknown. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pbc.27917DOI Listing
November 2019
4 Reads

Solitary Extra-axial Intracranial Primary Meningeal Pleomorphic Xanthoastrocytoma: An Extremely Rare Case.

World Neurosurg 2019 Oct 8;130:386-390. Epub 2019 Jul 8.

Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.

Background: Pleomorphic xanthoastrocytomas (PXAs) are a rare type of astrocytoma, which, similar to other gliomas, can rarely arise from glial nests in the meninges, manifesting as an extra-axial mass. We describe a solitary extra-axial intracranial primary meningeal PXA in the pediatric age group, which was masquerading as a tentorial meningioma.

Case Description: A 9-year-old girl presented with features of raised intracranial pressure. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2019.06.218DOI Listing
October 2019
2 Reads
2.417 Impact Factor

Case Report of Spinal Cord Astrocytoma Presenting with Extensive Spinal Vertebral Body Destruction.

World Neurosurg X 2019 Apr 1;2:100016. Epub 2019 Feb 1.

Department of Neuropathology, University of Rochester School of Medicine, Rochester, New York, USA.

Background: Spinal cord astrocytomas are rare lesions in adults.

Case Description: In this report, we present the case of a 28-year-old female patient who presented with a 2-year history of back pain and 3-month history of leg weakness. Magnetic resonance imaging of the patient showed an intrinsic expansive spinal cord lesion with extensive vertebral body destruction. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wnsx.2019.100016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580895PMC
April 2019
16 Reads

Primary spinal pilocytic astrocytoma: clinical study with long-term follow-up in 16 patients and a literature review.

Neurosurg Rev 2020 Apr 16;43(2):719-727. Epub 2019 May 16.

Department of neurosurgery, West China Hospital of Sichuan University, No. 37, GuoXue Alley, Chengdu, 610041, China.

Primary pilocytic astrocytoma (PA) of the spine is extremely rare and most published case series only include only a few patients. We attempted to explore the clinical features, radiological findings, and treatment outcomes of patients with spinal PA. Sixteen spinal PA patients who were surgically treated in our hospital between April 2008 and June 2018 were included in this retrospective study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10143-019-01109-0DOI Listing
April 2020
5 Reads

Contrast-enhancement in supratentorial low-grade gliomas: a classic prognostic factor in the molecular age.

J Neurooncol 2019 Jul 3;143(3):515-523. Epub 2019 May 3.

Unit of Neuro-Oncology, Hospital Universitari de Bellvitge-Institut Català D'Oncologia L'Hospitalet, IDIBELL (Oncobell Program), Feixa Llarga s/n, 08907, Barcelona, Spain.

Background: Contrast enhancement (CE) is found in 10-60% of low-grade gliomas. Its prognostic significance is controversial, and its correlation with IDH mutations and 1p/19q codeletion is elusive. The aim of this study is to investigate whether CE is associated with molecular characteristics of low-grade gliomas and uncover its prognostic value. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11060-019-03183-2DOI Listing
July 2019
6 Reads

A novel mutation in the gene expands the phenotype of Alexander disease.

J Med Genet 2019 12 19;56(12):846-849. Epub 2019 Apr 19.

Neurometabolic Diseases Laboratory, Institut d'Investigacio Biomedica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat (Barcelona), Catalonia, Spain

Background: Alexander disease, an autosomal dominant leukodystrophy, is caused by missense mutations in . Although mostly diagnosed in children, associated with severe leukoencephalopathy, milder adult forms also exist.

Methods: A family affected by adult-onset spastic paraplegia underwent neurological examination and cerebral MRI. Read More

View Article

Download full-text PDF

Source
http://jmg.bmj.com/lookup/doi/10.1136/jmedgenet-2018-105959
Publisher Site
http://dx.doi.org/10.1136/jmedgenet-2018-105959DOI Listing
December 2019
25 Reads
6.335 Impact Factor

Holocord Pilocytic Astrocytoma in an Adult: A Rare Case Report and Review of the Literature.

World Neurosurg 2019 Jun 19;126:369-375. Epub 2019 Mar 19.

Memorial Hospital, Neurosurgery Clinic, Ankara, Turkey.

Background: Intramedullary glial neoplasms affecting the entire spinal cord from the cervicomedullary junction to conus medullaris are termed holocord tumors. Pilocytic astrocytomas are relatively uncommon tumors forming holocord involvement. Hitherto 24 holocord astrocytoma cases were reported in the literature. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2019.03.103DOI Listing
June 2019
7 Reads
2.417 Impact Factor

Outcomes Following Proton Therapy for Pediatric Low-Grade Glioma.

Int J Radiat Oncol Biol Phys 2019 05 23;104(1):149-156. Epub 2019 Jan 23.

Department of Radiation Oncology, University of Florida College of Medicine, Jacksonville, Florida.

Purpose: Dosimetric studies show that proton therapy can reduce the low/intermediate radiation dose to uninvolved tissue in children with low-grade glioma (LGG). For this reason, LGG is the fourth most common pediatric tumor treated with proton therapy, yet clinical outcome data on efficacy and toxicity are limited.

Methods And Materials: We reviewed the medical records of 174 children (≤21 years old) with nonmetastatic LGG enrolled on a prospective protocol and treated with proton therapy between 2007 and 2017. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijrobp.2019.01.078DOI Listing
May 2019
57 Reads

Early Postoperative F-FET PET/MRI for Pediatric Brain and Spinal Cord Tumors.

J Nucl Med 2019 08 25;60(8):1053-1058. Epub 2019 Jan 25.

Department of Clinical Physiology, Nuclear Medicine, and PET, Copenhagen University Hospital, Rigshospitalet, Denmark.

Complete resection is the treatment of choice for most pediatric brain tumors, but early postoperative MRI for detection of residual tumor may be misleading because of MRI signal changes caused by the operation. PET imaging with amino acid tracers in adults increases the diagnostic accuracy for brain tumors, but the literature in pediatric neurooncology is limited. A hybrid PET/MRI system is highly beneficial in children, reducing the number of scanning procedures, and this is to our knowledge the first larger study using PET/MRI in pediatric neurooncology. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2967/jnumed.118.220293DOI Listing
August 2019
1 Read

MR imaging features of spinal pilocytic astrocytoma.

BMC Med Imaging 2019 01 14;19(1). Epub 2019 Jan 14.

Department of Radiology, Huashan Hospital, Fudan University, 12 Middle Wulumuqi Road, Jingan District, Shanghai, China.

Background: The purpose of this retrospective review is to determine the MR imaging features of pilocytic astrocytoma (PA) in the spinal cord to help neuroradiologists preoperatively differentiate PA from other intramedullary tumors.

Methods: Neuro-oncology database review revealed 13 consecutive patients with a pathological spinal PA diagnosis and availability of preoperative MR imaging. Three patients had preoperative diffusion-weighted MR imaging. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12880-018-0296-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332544PMC
January 2019
11 Reads

Tanycytic ependymoma of filum terminale: Clinical characteristics and surgical outcomes.

Oncol Lett 2018 Dec 1;16(6):6910-6917. Epub 2018 Oct 1.

Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, P.R. China.

Tanycytic ependymoma (TE), a rare subtype of ependymoma, was classified as grade II ependymoma by the World Health Organization in 2000 and 2007. Preoperative diagnosis of TE is challenging due to its similarities to schwannoma and astrocytoma; therefore, differentiation is required. The present study investigated the clinical, imaging and pathological characteristics of TE in the filum terminale. Read More

View Article

Download full-text PDF

Source
http://www.spandidos-publications.com/10.3892/ol.2018.9531
Publisher Site
http://dx.doi.org/10.3892/ol.2018.9531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256739PMC
December 2018
16 Reads

Intramedullary spinal cord ependymoma and astrocytoma: intraoperative frozen-section diagnosis, extent of resection, and outcomes.

J Neurosurg Spine 2018 10;30(1):133-139

Departments of1Neurosurgery and.

OBJECTIVEThe intraoperative differentiation of ependymomas from astrocytomas is important because neurosurgical strategies differ between these two tumor groups. Previous studies have reported that the diagnostic accuracy of intraoperative frozen sections of intracranial central nervous system (CNS) tumors is higher than 83%-97%, whereas that for spinal intramedullary tumors remains unknown. Herein, authors tested the hypothesis that intraoperative frozen-section diagnosis is the gold standard for a differential diagnosis of intramedullary spinal cord tumors. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3171/2018.7.SPINE18230DOI Listing
October 2018
17 Reads

Exophytic Primary Intramedullary Spinal Cord Glioblastoma: Case Report and Critical Review of Literature.

World Neurosurg 2019 Feb 23;122:573-576. Epub 2018 Nov 23.

Department of Radiology, Huashan Hospital, Fudan University, Jing'an District, Shanghai, China. Electronic address:

Background: Primary intramedullary spinal cord (IMSC) glioblastoma (GBM) is an extremely rare entity; we report the first case of primary IMSC GBM presenting with exophytic involvement. The prognosis of glioblastoma remains poor due to the aggressive nature of the disease and lack of effective treatment.

Case Description: A 27-year-old Asian female presented to our hospital with a 1-month history of dysuria, incomplete bladder emptying, progressive numbness, and weakness of both lower limbs, as well as a 1-year history of back pain. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S18788750183266
Publisher Site
http://dx.doi.org/10.1016/j.wneu.2018.11.113DOI Listing
February 2019
21 Reads

Incidence of initial spinal metastasis in glioblastoma patients and the importance of spinal screening using MRI.

J Neurooncol 2019 Jan 9;141(2):337-345. Epub 2018 Nov 9.

Department of Neurosurgery, Tohoku University School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan.

Purpose: Intracranial glioblastomas with simultaneous spinal lesions prior to chemoradiation therapy or craniotomy, defined as initial spinal metastasis, are not well understood. Herein, we investigated intracranial glioblastoma and demonstrated the importance of spinal screening using gadolinium enhanced spinal magnetic resonance imaging (Gd-MRI).

Methods: Consecutive adult patients with intracranial glioblastoma were treated between 2010 and 2014 and received spinal screening using Gd-MRI. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11060-018-03036-4DOI Listing
January 2019
4 Reads

Unusual Clinical Presentation and Association of Cranial Dermoid Tumor and Tethered Cord Syndrome.

Pediatr Neurosurg 2018 8;53(6):427-431. Epub 2018 Nov 8.

Bahcesehir University, Faculty of Medicine, Department of Neurosurgery, Gaziantep Medical Park Hospital, Gaziantep, Turkey.

Tethered cord syndrome (TCS), a neurological disorder characterized by the lower settlement of the conus medullaris, is a congenital spinal disease which is caused by split cord syndrome, meningomyelocele, and spinal tumors. Cranial dermoid tumor (CDT) is a congenital benign tumor which is generally located on the midline of the cranium. Even though TCS is highly associated with spinal dermoid tumor, the relationship of CDT and TCS is unusual. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000494087DOI Listing
January 2019
75 Reads
0.500 Impact Factor

Radiographer reporting of neurological magnetic resonance imaging examinations of the head and cervical spine: Findings of an accredited postgraduate programme.

Radiography (Lond) 2018 11 18;24(4):366-369. Epub 2018 Jun 18.

School of Allied Health Professions, Canterbury Christ Church University, Canterbury, Kent, UK; Radiology Department, Homerton University Hospital, UK.

Introduction: To analyse the objective structured examination (OSE) results of the first cohorts of radiographers (n = 13) who successfully completed an accredited postgraduate programme in clinical reporting of neurological magnetic resonance imaging (MRI) examinations of the head and cervical spine.

Methods: Forty MRI examinations were used in the OSE which included a range of abnormal cases (prevalence of abnormal examinations approximated 50%) and included: haemorrhage, infarction, demyelination disease, abscess, mass lesions (metastatic deposits, meningioma, glioma, astrocytoma); and disc disease, cord compression, stenosis, ligament rupture, syringomyelia appearances on patients referred from a range of referral sources. Normal variants and incidental findings were also included. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.radi.2018.05.006DOI Listing
November 2018
4 Reads

Leptomeningeal dissemination of spinal pilocytic astrocytoma: a rare entity.

BMJ Case Rep 2018 Sep 28;2018. Epub 2018 Sep 28.

Oncology, NHS Lothian, Edinburgh, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2018-226955DOI Listing
September 2018
5 Reads

Extensive Leptomeningeal Intracranial and Spinal Metastases in a Patient with a Supratentorial Glioblastoma Multiforme, IDH-Wildtype.

World Neurosurg 2018 Dec 22;120:442-447. Epub 2018 Sep 22.

Department of Neurosurgery, University Hospital Salzburg, Paracelsus Medical University, Salzburg, Austria.

Background: Glioblastoma multiforme (GBM) is usually characterized by diffuse, infiltrative growth and local tumor progression. Extensive leptomeningeal metastases are rarely observed. It is unclear which GBMs are prone to this specific growth pattern and progression, and standardized salvage treatment protocols are unavailable. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2018.09.082DOI Listing
December 2018
15 Reads

Biopsying a spinal cord lesion: A diagnostic dilemma. Case report and review of literature.

Neurochirurgie 2018 Dec 19;64(6):425-430. Epub 2018 Sep 19.

Service de neurochirurgie, CHU de Strasbourg, hôpital de Hautepierre, 67000 Strasbourg, France.

Spinal cord biopsy is a difficult procedure fraught with the risk of false-negative results or even misdiagnosis in up to 30% of cases. Differential diagnoses of spinal cord lesions include a wide range of inflammatory, infectious and neoplastic diseases. Given the importance of correctly managing these pathologies, it is crucial to avoid delays in making the correct diagnosis in order to improve the patient's outcome. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuchi.2018.07.002DOI Listing
December 2018
3 Reads

Clinical Significance of T2*gradient-recalled Echo/susceptibility-weighted Imaging Sequences in Evaluating Superficial Siderosis in the Setting of Intracerebral Tumors: Pilocytic Astrocytoma.

J Clin Imaging Sci 2018 24;8:36. Epub 2018 Aug 24.

Department of Radiology, SUNY Upstate Medical University, NY, USA.

Superficial siderosis is the slow accumulation of hemosiderin on the pial surfaces of the brain and spinal cord. The most common cause of intracranial superficial siderosis is secondary to subarachnoid hemorrhage. Rarely, superficial siderosis can also be caused by tumors. Read More

View Article

Download full-text PDF

Source
http://www.clinicalimagingscience.org/text.asp?2018/8/1/36/2
Publisher Site
http://dx.doi.org/10.4103/jcis.JCIS_60_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118113PMC
August 2018
13 Reads

Rosette-Forming Glioneuronal Tumor of Spinal Cord.

World Neurosurg 2018 11 16;119:242-243. Epub 2018 Aug 16.

Department of Radiology, Rothschild Ophthalmological Foundation, Paris, France.

Rosette-forming glioneuronal tumor has recently been included in the World Health Organization classification as a low-grade tumor. It usually occurs in young adults, arising from the fourth ventricular region. The authors describe a rare case of rosette-forming glioneuronal tumor arising from the spinal cord with cerebrospinal fluid dissemination. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2018.08.035DOI Listing
November 2018
3 Reads

An elderly patient presenting with a primary spinal multifocal intradural extramedullary pilocytic astrocytoma: a case report and review of the literature.

BMC Cancer 2018 Aug 9;18(1):806. Epub 2018 Aug 9.

Departments of Neurology, University of Louisville School of Medicine, Louisville, KY, 40202, USA.

Background: Pilocytic astrocytoma is a low-grade central nervous system tumor most commonly seen in children. Dissemination from a primary intracranial tumor along the neuroaxis has been described at both presentation and disease progression. However, the development of an intradural extramedullary pilocytic astrocytoma independent of a primary intraparenchymal tumor in an adult patient with no history of pilocytic astrocytoma has rarely been reported. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12885-018-4721-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085645PMC
August 2018
28 Reads

Resection of a Pediatric Intramedullary Spinal Cord Tumor: 2-Dimensional Operative Video.

Oper Neurosurg (Hagerstown) 2019 Apr;16(4):518

Department of Neurosurgery, University of Iowa Carver College of Medicine, Iowa City, Iowa.

This video is a case presentation and demonstration of surgical approach to a pediatric intramedullary spinal cord tumor (IMSCT). IMSCT can be associated with significant morbidity and aggressive resection is associated with more favorable long-term outcome. A 13-yr-old male presented to clinic for evaluation of rapidly progressive scoliosis to the left. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ons/opy185DOI Listing
April 2019
45 Reads

Purely neuroendoscopic resection of intraventricular tumors with an endoscopic ultrasonic aspirator.

Neurosurg Rev 2019 Dec 17;42(4):973-982. Epub 2018 Jul 17.

Neurosurgery Department, Regional University Hospital, Carlos Haya Avenue, 29010, Málaga, Spain.

Surgery for intraventricular tumors remains a controversial and evolving field, with endoscopic resection becoming more popular. We present a series of nine consecutive cases of purely endoscopic resection of intraventricular tumors with the aid of an ultrasonic aspirator specific for neuroendoscopy. Nine patients (five men, four women) aged 18-74 years (mean 43. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10143-018-1011-8DOI Listing
December 2019
9 Reads

Primary Spinal Cord Small-Cell Glioblastoma: Case Report and Literature Review.

World Neurosurg 2018 Oct 11;118:69-70. Epub 2018 Jul 11.

Department of Neurosurgery, Tecnologico de Monterrey, Monterrey, Nuevo Leon, Mexico.

Background: Approximately 2%-10% of all central nervous system tumors are primary spinal cord tumors (SCTs). Spinal cord glioblastoma is a rare tumor type accounting for 1%-3% of all SCTs and 7.5% of all spinal cord gliomas. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2018.07.007DOI Listing
October 2018
10 Reads

Pseudoprogression successfully treated with bevacizumab in a child with spinal pilocytic astrocytoma.

Childs Nerv Syst 2018 11 27;34(11):2305-2308. Epub 2018 May 27.

Department of Pediatrics, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan.

Clinical Case: We report on a 7-year-old female with spinal pilocytic astrocytoma complicated by pseudoprogression 1 month after completion of radiation therapy. Although she was initially treated with high-dose steroids, her clinical symptoms did not completely resolve, and magnetic resonance imaging (MRI) revealed extension of the lesions into the medulla oblongata. Treatment with bevacizumab was commenced, followed by rapid resolution of the clinical symptoms and improvements in the MRI findings. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00381-018-3841-7DOI Listing
November 2018
5 Reads

An unusual cause of combined cauda equina and conus medullaris syndrome.

Neurol India 2018 May-Jun;66(3):886-888

Department of Spine Surgery, VPS Lakeshore Hospital, Ernakulam, Kerala, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/0028-3886.232280DOI Listing
September 2019
2 Reads

Primary spinal cord glioblastoma metastasizing to the cerebellum: A missed entity.

Neurol India 2018 May-Jun;66(3):854-857

Department of Neurological Sciences, Christian Medical College, Vellore, Tamil Nadu, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/0028-3886.232347DOI Listing
September 2019
4 Reads

Intradural Lumbar Migration of Intracranial Neurosurgical Hemostatic Clip Associated with Lumbosciatic Pain.

World Neurosurg 2018 Jul 22;115:166-169. Epub 2018 Apr 22.

Department of Orthopedic Surgery, Spine Unit, Rouen University Hospital, Rouen, France. Electronic address:

Background: Clips implanted during intracranial neurosurgical procedures sometimes migrate intradurally with rare cases of spinal migration. The appearance of radicular symptoms of topography concordant with the position of the foreign body leads to discussion about the optimal therapeutic strategy.

Case Description: We report the case of a 52-year-old woman suffering from L5 radicular pain resistant to medical treatment in the presence of L4L5 lumbar stenosis and a neurosurgical clip migrated to the L5S1 level. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2018.04.082DOI Listing
July 2018
19 Reads

Intraspinal intradural nodular fasciitis mimicking glioblastoma metastasis: a case report.

Folia Neuropathol 2018 ;56(1):75-79

We report the case of a 78-year-old male patient suffering from right temporal glioblastoma with radiographic meningeal tumor spread. During the further course of the disease he developed a rapidly progressive paraplegia. An magnetic resonance imaging scan showed a contrast enhancing an intraspinal intradural lesion with compression of the myelon on segment Th 8/9. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/fn.2018.74662DOI Listing
September 2018
7 Reads