693 results match your criteria Spinal Imaging in Astrocytoma


Outcomes Following Proton Therapy for Pediatric Low-Grade Glioma.

Int J Radiat Oncol Biol Phys 2019 Jan 23. Epub 2019 Jan 23.

Department of Radiation Oncology, University of Florida College of Medicine, Jacksonville, FL.

Background/objectives: Dosimetric studies show that proton therapy can reduce the low/intermediate radiation dose to uninvolved tissue in children with low-grade glioma (LGG). For this reason, LGG is the 4th most common pediatric tumor treated with proton therapy, yet clinical outcome data on efficacy and toxicity are limited.

Design/methods: We reviewed the medical records of 174 children (≤21 years old) with non-metastatic LGG enrolled on a prospective protocol and treated with proton therapy between 2007 and 2017 to assess clinical outcomes and toxicity, and analyze patient, tumor, and treatment-related variables. Read More

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http://dx.doi.org/10.1016/j.ijrobp.2019.01.078DOI Listing
January 2019
15 Reads

MR imaging features of spinal pilocytic astrocytoma.

BMC Med Imaging 2019 Jan 14;19(1). Epub 2019 Jan 14.

Department of Radiology, Huashan Hospital, Fudan University, 12 Middle Wulumuqi Road, Jingan District, Shanghai, China.

Background: The purpose of this retrospective review is to determine the MR imaging features of pilocytic astrocytoma (PA) in the spinal cord to help neuroradiologists preoperatively differentiate PA from other intramedullary tumors.

Methods: Neuro-oncology database review revealed 13 consecutive patients with a pathological spinal PA diagnosis and availability of preoperative MR imaging. Three patients had preoperative diffusion-weighted MR imaging. Read More

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http://dx.doi.org/10.1186/s12880-018-0296-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332544PMC
January 2019
1 Read

Tanycytic ependymoma of filum terminale: Clinical characteristics and surgical outcomes.

Oncol Lett 2018 Dec 1;16(6):6910-6917. Epub 2018 Oct 1.

Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, P.R. China.

Tanycytic ependymoma (TE), a rare subtype of ependymoma, was classified as grade II ependymoma by the World Health Organization in 2000 and 2007. Preoperative diagnosis of TE is challenging due to its similarities to schwannoma and astrocytoma; therefore, differentiation is required. The present study investigated the clinical, imaging and pathological characteristics of TE in the filum terminale. Read More

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http://www.spandidos-publications.com/10.3892/ol.2018.9531
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http://dx.doi.org/10.3892/ol.2018.9531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256739PMC
December 2018
7 Reads

Intramedullary spinal cord ependymoma and astrocytoma: intraoperative frozen-section diagnosis, extent of resection, and outcomes.

Authors:

J Neurosurg Spine 2018 Oct 1:1-7. Epub 2018 Oct 1.

OBJECTIVEThe intraoperative differentiation of ependymomas from astrocytomas is important because neurosurgical strategies differ between these two tumor groups. Previous studies have reported that the diagnostic accuracy of intraoperative frozen sections of intracranial central nervous system (CNS) tumors is higher than 83%-97%, whereas that for spinal intramedullary tumors remains unknown. Herein, authors tested the hypothesis that intraoperative frozen-section diagnosis is the gold standard for a differential diagnosis of intramedullary spinal cord tumors. Read More

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http://dx.doi.org/10.3171/2018.7.SPINE18230DOI Listing
October 2018
2 Reads

Unusual Clinical Presentation and Association of Cranial Dermoid Tumor and Tethered Cord Syndrome.

Pediatr Neurosurg 2018 8;53(6):427-431. Epub 2018 Nov 8.

Bahcesehir University, Faculty of Medicine, Department of Neurosurgery, Gaziantep Medical Park Hospital, Gaziantep, Turkey.

Tethered cord syndrome (TCS), a neurological disorder characterized by the lower settlement of the conus medullaris, is a congenital spinal disease which is caused by split cord syndrome, meningomyelocele, and spinal tumors. Cranial dermoid tumor (CDT) is a congenital benign tumor which is generally located on the midline of the cranium. Even though TCS is highly associated with spinal dermoid tumor, the relationship of CDT and TCS is unusual. Read More

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http://dx.doi.org/10.1159/000494087DOI Listing
January 2019
34 Reads
0.500 Impact Factor

Leptomeningeal dissemination of spinal pilocytic astrocytoma: a rare entity.

BMJ Case Rep 2018 Sep 28;2018. Epub 2018 Sep 28.

Oncology, NHS Lothian, Edinburgh, UK.

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http://dx.doi.org/10.1136/bcr-2018-226955DOI Listing
September 2018
2 Reads

Extensive Leptomeningeal Intracranial and Spinal Metastases in a Patient with a Supratentorial Glioblastoma Multiforme, IDH-Wildtype.

World Neurosurg 2018 Dec 22;120:442-447. Epub 2018 Sep 22.

Department of Neurosurgery, University Hospital Salzburg, Paracelsus Medical University, Salzburg, Austria.

Background: Glioblastoma multiforme (GBM) is usually characterized by diffuse, infiltrative growth and local tumor progression. Extensive leptomeningeal metastases are rarely observed. It is unclear which GBMs are prone to this specific growth pattern and progression, and standardized salvage treatment protocols are unavailable. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.09.082DOI Listing
December 2018
8 Reads

Biopsying a spinal cord lesion: A diagnostic dilemma. Case report and review of literature.

Neurochirurgie 2018 Dec 19;64(6):425-430. Epub 2018 Sep 19.

Service de neurochirurgie, CHU de Strasbourg, hôpital de Hautepierre, 67000 Strasbourg, France.

Spinal cord biopsy is a difficult procedure fraught with the risk of false-negative results or even misdiagnosis in up to 30% of cases. Differential diagnoses of spinal cord lesions include a wide range of inflammatory, infectious and neoplastic diseases. Given the importance of correctly managing these pathologies, it is crucial to avoid delays in making the correct diagnosis in order to improve the patient's outcome. Read More

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http://dx.doi.org/10.1016/j.neuchi.2018.07.002DOI Listing
December 2018

Clinical Significance of T2*gradient-recalled Echo/susceptibility-weighted Imaging Sequences in Evaluating Superficial Siderosis in the Setting of Intracerebral Tumors: Pilocytic Astrocytoma.

J Clin Imaging Sci 2018 24;8:36. Epub 2018 Aug 24.

Department of Radiology, SUNY Upstate Medical University, NY, USA.

Superficial siderosis is the slow accumulation of hemosiderin on the pial surfaces of the brain and spinal cord. The most common cause of intracranial superficial siderosis is secondary to subarachnoid hemorrhage. Rarely, superficial siderosis can also be caused by tumors. Read More

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http://www.clinicalimagingscience.org/text.asp?2018/8/1/36/2
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http://dx.doi.org/10.4103/jcis.JCIS_60_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118113PMC
August 2018
7 Reads

Rosette-Forming Glioneuronal Tumor of Spinal Cord.

World Neurosurg 2018 11 16;119:242-243. Epub 2018 Aug 16.

Department of Radiology, Rothschild Ophthalmological Foundation, Paris, France.

Rosette-forming glioneuronal tumor has recently been included in the World Health Organization classification as a low-grade tumor. It usually occurs in young adults, arising from the fourth ventricular region. The authors describe a rare case of rosette-forming glioneuronal tumor arising from the spinal cord with cerebrospinal fluid dissemination. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.08.035DOI Listing
November 2018
1 Read

An elderly patient presenting with a primary spinal multifocal intradural extramedullary pilocytic astrocytoma: a case report and review of the literature.

BMC Cancer 2018 Aug 9;18(1):806. Epub 2018 Aug 9.

Departments of Neurology, University of Louisville School of Medicine, Louisville, KY, 40202, USA.

Background: Pilocytic astrocytoma is a low-grade central nervous system tumor most commonly seen in children. Dissemination from a primary intracranial tumor along the neuroaxis has been described at both presentation and disease progression. However, the development of an intradural extramedullary pilocytic astrocytoma independent of a primary intraparenchymal tumor in an adult patient with no history of pilocytic astrocytoma has rarely been reported. Read More

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http://dx.doi.org/10.1186/s12885-018-4721-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085645PMC
August 2018
6 Reads

Resection of a Pediatric Intramedullary Spinal Cord Tumor: 2-Dimensional Operative Video.

Oper Neurosurg (Hagerstown) 2018 Jul 31. Epub 2018 Jul 31.

Department of Neurosurgery, University of Iowa Carver College of Medicine, Iowa City, Iowa.

This video is a case presentation and demonstration of surgical approach to a pediatric intramedullary spinal cord tumor (IMSCT). IMSCT can be associated with significant morbidity and aggressive resection is associated with more favorable long-term outcome. A 13-yr-old male presented to clinic for evaluation of rapidly progressive scoliosis to the left. Read More

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http://dx.doi.org/10.1093/ons/opy185DOI Listing
July 2018
13 Reads

Purely neuroendoscopic resection of intraventricular tumors with an endoscopic ultrasonic aspirator.

Neurosurg Rev 2018 Jul 17. Epub 2018 Jul 17.

Neurosurgery Department, Regional University Hospital, Carlos Haya Avenue, 29010, Málaga, Spain.

Surgery for intraventricular tumors remains a controversial and evolving field, with endoscopic resection becoming more popular. We present a series of nine consecutive cases of purely endoscopic resection of intraventricular tumors with the aid of an ultrasonic aspirator specific for neuroendoscopy. Nine patients (five men, four women) aged 18-74 years (mean 43. Read More

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http://dx.doi.org/10.1007/s10143-018-1011-8DOI Listing
July 2018
3 Reads

Primary Spinal Cord Small-Cell Glioblastoma: Case Report and Literature Review.

World Neurosurg 2018 Oct 11;118:69-70. Epub 2018 Jul 11.

Department of Neurosurgery, Tecnologico de Monterrey, Monterrey, Nuevo Leon, Mexico.

Background: Approximately 2%-10% of all central nervous system tumors are primary spinal cord tumors (SCTs). Spinal cord glioblastoma is a rare tumor type accounting for 1%-3% of all SCTs and 7.5% of all spinal cord gliomas. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.07.007DOI Listing
October 2018
5 Reads

Pseudoprogression successfully treated with bevacizumab in a child with spinal pilocytic astrocytoma.

Childs Nerv Syst 2018 Nov 27;34(11):2305-2308. Epub 2018 May 27.

Department of Pediatrics, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan.

Clinical Case: We report on a 7-year-old female with spinal pilocytic astrocytoma complicated by pseudoprogression 1 month after completion of radiation therapy. Although she was initially treated with high-dose steroids, her clinical symptoms did not completely resolve, and magnetic resonance imaging (MRI) revealed extension of the lesions into the medulla oblongata. Treatment with bevacizumab was commenced, followed by rapid resolution of the clinical symptoms and improvements in the MRI findings. Read More

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http://dx.doi.org/10.1007/s00381-018-3841-7DOI Listing
November 2018
3 Reads

Intradural Lumbar Migration of Intracranial Neurosurgical Hemostatic Clip Associated with Lumbosciatic Pain.

World Neurosurg 2018 Jul 22;115:166-169. Epub 2018 Apr 22.

Department of Orthopedic Surgery, Spine Unit, Rouen University Hospital, Rouen, France. Electronic address:

Background: Clips implanted during intracranial neurosurgical procedures sometimes migrate intradurally with rare cases of spinal migration. The appearance of radicular symptoms of topography concordant with the position of the foreign body leads to discussion about the optimal therapeutic strategy.

Case Description: We report the case of a 52-year-old woman suffering from L5 radicular pain resistant to medical treatment in the presence of L4L5 lumbar stenosis and a neurosurgical clip migrated to the L5S1 level. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.04.082DOI Listing
July 2018
7 Reads

Intraspinal intradural nodular fasciitis mimicking glioblastoma metastasis: a case report.

Folia Neuropathol 2018 ;56(1):75-79

We report the case of a 78-year-old male patient suffering from right temporal glioblastoma with radiographic meningeal tumor spread. During the further course of the disease he developed a rapidly progressive paraplegia. An magnetic resonance imaging scan showed a contrast enhancing an intraspinal intradural lesion with compression of the myelon on segment Th 8/9. Read More

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http://dx.doi.org/10.5114/fn.2018.74662DOI Listing
September 2018
3 Reads

Spinal cord astrocytoma: a unique presentation of abdominal pain.

Radiol Case Rep 2018 Feb 18;13(1):284-288. Epub 2017 Oct 18.

Medical College of Virginia, Richmond, VA 23219, USA.

A previously healthy male presented at age 5 years with recurrent abdominal pain that occurred diffusely. The pain was severe enough to cause episodic screaming, especially at night with spontaneous resolution. The patient was initially treated for constipation but when motor symptoms began to develop, imaging revealed the cause of his pain to be a spinal cord mass. Read More

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http://dx.doi.org/10.1016/j.radcr.2017.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826690PMC
February 2018
1 Read

Intradural spinal tumors in adults-update on management and outcome.

Neurosurg Rev 2018 Feb 17. Epub 2018 Feb 17.

Department of Neurosurgery, Vivantes Klinikum Neukölln, Berlin, Germany.

Among spinal tumors that occur intradurally, meningiomas, nerve sheath tumors, ependymomas, and astrocytomas are the most common. While a spinal MRI is the state of the art to diagnose intradural spinal tumors, in some cases CT scans, angiography, CSF analyses, and neurophysiological examination can be valuable. The management of these lesions depends not only on the histopathological diagnosis but also on the clinical presentation and the anatomical location, allowing either radical resection as with most extramedullary lesions or less invasive strategies as with intramedullary lesions. Read More

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http://dx.doi.org/10.1007/s10143-018-0957-xDOI Listing
February 2018
50 Reads

Exophytic Cerebral Hemispheric Low-Grade Glioma: Unusual Growth Pattern of Common Central Nervous System Tumor.

World Neurosurg 2018 May 15;113:184-187. Epub 2018 Feb 15.

Department of Neurosurgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.

Background: Exophytic growth (EG), wherein the tumor mass grows beyond the neuraxial boundary formed by pia mater, remains a rare pattern of glioma growth. It has been described in gliomas at several locations like the brainstem, cerebellum, suprasellar area, spinal cord, and insula. However, EG in hemispheric grade 2 astrocytomas, particularly affecting the convexity subarachnoid space, as against the more spacious basal subarachnoid space, is exceedingly rare. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183031
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http://dx.doi.org/10.1016/j.wneu.2018.02.048DOI Listing
May 2018
3 Reads
2.420 Impact Factor

Postoperative extracranial metastasis from glioblastoma: a case report and review of the literature.

World J Surg Oncol 2017 Dec 29;15(1):231. Epub 2017 Dec 29.

Neurosurgical Research Institute, The First Affiliated Hospital of Guangdong Pharmaceutics University, Guangzhou, 510060, China.

Background: Glioblastoma is the most common primary malignant brain tumor. Extraneural metastases are rarely reported in the literature.

Case Presentation: We report a case of a 38-year-old patient who was diagnosed with glioblastoma in 2015. Read More

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http://dx.doi.org/10.1186/s12957-017-1300-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747170PMC
December 2017
11 Reads
1.200 Impact Factor

Expression of CD133 as a Putative Prognostic Biomarker to Predict Intracranial Dissemination of Primary Spinal Cord Astrocytoma.

World Neurosurg 2018 Feb 24;110:e715-e726. Epub 2017 Nov 24.

Department of Neurosurgery, Tohoku University, Graduate School of Medicine, Sendai, Miyagi, Japan.

Objective: Spinal cord astrocytoma with intracranial dissemination carries a poor prognosis. The mechanisms leading to dissemination remain to be elucidated. A stem cell marker, CD133, was reported to predict recurrence patterns in intracranial glioblastoma. Read More

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http://dx.doi.org/10.1016/j.wneu.2017.11.089DOI Listing
February 2018
15 Reads

Thoracic Spinal Cord Glioblastoma Mimicking Epidural Abscess: Case Report and Literature Review.

Cureus 2017 Aug 31;9(8):e1631. Epub 2017 Aug 31.

Neurological Surgery, OhioHealth.

Spinal cord glioblastoma (SG) accounts for 1.5% of all spinal tumors and has a poor prognosis with survival ranging from 2 to 26 months from presentation. A 57-year-old male presented with one week of paraparesis and contrasted magnetic resonance imaging (MRI) findings of an epidural enhancing thoracic mass suspicious for an epidural abscess. Read More

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http://dx.doi.org/10.7759/cureus.1631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663322PMC
August 2017
6 Reads

5-ALA-Induced Fluorescence in Leptomeningeal Dissemination of Spinal Malignant Glioma.

World Neurosurg 2018 Feb 21;110:345-348. Epub 2017 Oct 21.

Department of Neurosurgery, Heinrich Heine University, Düsseldorf, Germany.

Background: 5-Aminolevulinic acid (5-ALA)-fluorescence-guided resection of malignant glioma is well established in many neuro-oncology departments. In addition, the use of 5-ALA has been reported for cerebral metastases, meningioma, and spinal tumors. We report a case of a patient with a leptomeningeal spread of a K27M-mutated spinal anaplastic astrocytoma (World Health Organization° [WHO] III), which was detected by its faint 5-ALA-induced fluorescence. Read More

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http://dx.doi.org/10.1016/j.wneu.2017.10.069DOI Listing
February 2018
1 Read

Fluorescein-Guided Resection of Intramedullary Spinal Cord Tumors: Results from a Preliminary, Multicentric, Retrospective Study.

World Neurosurg 2017 Dec 19;108:603-609. Epub 2017 Sep 19.

Department of Neurosurgery, University Medical Center, Regensburg, Germany.

Background: Intramedullary spinal cord tumors (IMSCTs) are rare, heterogenous lesions that are usually enhanced on preoperative magnetic resonance imaging (MRI) because of a damaged blood-brain barrier. Sodium fluorescein is a dye that accumulates in areas of the central nervous system with a damaged BBB. Given the pattern of MRI contrast enhancement of the majority of IMSCTs, the use of this fluorescent tracer could improve tumor visualization and quality of resection. Read More

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http://dx.doi.org/10.1016/j.wneu.2017.09.061DOI Listing
December 2017
25 Reads

Characterization of brain tumours with spin-spin relaxation: pilot case study reveals unique T distribution profiles of glioblastoma, oligodendroglioma and meningioma.

J Neurol 2017 Nov 11;264(11):2205-2214. Epub 2017 Sep 11.

Radiology, University of British Columbia, Vancouver, Canada.

Prolonged spin-spin relaxation times in tumour tissue have been observed since some of the earliest nuclear magnetic resonance investigations of the brain. Over the last three decades, numerous studies have sought to characterize tumour morphology and malignancy using quantitative assessment of T relaxation times, although attempts to categorize and differentiate tumours have had limited success. However, previous work must be interpreted with caution as relaxation data were typically acquired using a variety of multiple echo sequences with a range of echoes and T decay curves and were frequently fit with monoexponential analysis. Read More

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http://link.springer.com/10.1007/s00415-017-8609-6
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http://dx.doi.org/10.1007/s00415-017-8609-6DOI Listing
November 2017
13 Reads

Lumbosacral Subdural Hematoma After Glioblastoma Multiforme Resection: Possible Radiographic Evidence for the Downward Migration of Intracranial Blood.

World Neurosurg 2017 Dec 7;108:993.e13-993.e17. Epub 2017 Sep 7.

Department of Neurosurgery, University of Virginia, Charlottesville, Virginia, USA.

Background: Spinal subdural hematomas (SSDHs) are rare and usually associated with bleeding diatheses, trauma, iatrogenic injury, spinal vascular malformations, or intraspinal tumors.

Case Description: We report a case of a 75-year-old man who developed a symptomatic lumbosacral SSDH after undergoing resection of a right temporal glioblastoma multiforme. The patient subsequently recovered and was discharged home. Read More

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http://dx.doi.org/10.1016/j.wneu.2017.08.189DOI Listing
December 2017
15 Reads

[Contribution of temozolomide chemotherapy for intramedullary grade II spinal cord astrocytomas in adults: Our experience].

Neurochirurgie 2017 Sep 4;63(4):297-301. Epub 2017 Sep 4.

Services de neurochirurgie, hôpital Erasme, route de Lennik, 808, 1070 Bruxelles, Belgique. Electronic address:

Introduction: Grade II intramedullary astrocytomas are rare tumors. Despite a well-defined role of adjuvant temozolomide chemotherapy for brain gliomas, the contribution of this therapy for intramedullary gliomas is not yet clearly defined.

Method: We retrospectively analyzed the data of 5 adult patients treated with temozolomide between 2008 and 2015 for a grade II intramedullary astrocytoma with progression after surgery. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00283770173010
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http://dx.doi.org/10.1016/j.neuchi.2017.05.002DOI Listing
September 2017
2 Reads

Spinal cord tumors in children: A review of 21 cases treated at the same institution.

Neurochirurgie 2017 Sep 1;63(4):291-296. Epub 2017 Sep 1.

Service de neurochirurgie et chirurgie de la face pédiatrique, hôpital d'enfants, université de Lorraine, CHRU Nancy, 4, rue du Morvan, 54500 Vandoeuvre-lès-Nancy, France. Electronic address:

Introduction: Spinal cord tumors in children (SCTC) are rare with a frequent diagnostic delay. Its management is multidisciplinary and challenging due to functional implications. The position of surgery is now better established but the role and timing of chemotherapy (CT) and radiotherapy (RT) still remains under debate. Read More

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http://dx.doi.org/10.1016/j.neuchi.2017.01.008DOI Listing
September 2017
1 Read

Spinal Cord Astrocytoma with Isocitrate Dehydrogenase 1 Gene Mutation.

World Neurosurg 2017 Dec 1;108:991.e13-991.e16. Epub 2017 Sep 1.

Department of Neurosurgery, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan.

Background: In 2016, the World Health Organization updated its classification of tumors, adding genetic profiles to the conventional histopathologic typing.

Case Description: The authors present herein the first case of a 44-year-old female with isocitrate dehydrogenase-mutant World Health Organization grade II diffuse spinal astrocytoma diagnosed on the basis of both histopathologic and genetic findings.

Conclusions: The present case underscores the significant role of a molecular genetic analysis in the differential diagnosis of intramedullary spinal gliomas. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750173144
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http://dx.doi.org/10.1016/j.wneu.2017.08.142DOI Listing
December 2017
21 Reads

Intramedullary Thoracic Spine Astrocytoma Presenting as Hydrocephalus in an Infant: A Case Report.

Pediatr Neurosurg 2017 26;52(5):327-330. Epub 2017 Aug 26.

Department of Neurosurgery, University of Southern California, Los Angeles, CA, USA.

We present the case of an intramedullary spinal cord tumor from C7 to T4, classified as a WHO grade I pilocytic astrocytoma, manifesting solely with isolated, acute hydrocephalus and a normal neurological exam in a 5-month-old infant. We discuss the common presenting symptoms of spinal cord tumors in the pediatric population and possible anatomical explanations for this unique presentation and offer recommendations for the management of isolated hydrocephalus in an infant. Read More

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http://dx.doi.org/10.1159/000479323DOI Listing
June 2018
5 Reads

Surgery for spinal intramedullary tumors: technique, outcome and factors affecting resectability.

Neurosurg Rev 2018 Apr 17;41(2):503-511. Epub 2017 Jul 17.

Department of Neurosurgery, Alexandria University, 20 Amin Fikry Str. Raml Station, Alexandria, 21131, Egypt.

Intramedullary spinal cord tumors (IMSCTs) are relatively infrequent lesions with ependymomas and astrocytomas representing the most common types. Microsurgical resection is established as the treatment of choice for these challenging lesions. We reviewed the surgical outcome of 29 cases operated for IMSCTs by the same surgeon between 2009 and 2015. Read More

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http://dx.doi.org/10.1007/s10143-017-0879-zDOI Listing
April 2018
4 Reads
1.861 Impact Factor

Clinicopathological and imaging features of lipoastrocytoma: Case report.

Neuroradiol J 2018 Feb 23;31(1):32-38. Epub 2017 Jun 23.

1 Department of Neurosurgery, Sri Sathya Sai Institute of Higher Medical Sciences, Whitefield, Bangalore, India.

Lipidized tumors of the central nervous system are very uncommon, with only a few cases described. We report a case of a 25-year-old woman with a tumor involving the left premotor area. She underwent gross total excision. Read More

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http://dx.doi.org/10.1177/1971400917710667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789993PMC
February 2018
17 Reads

Cervical spinal glioblastoma multiforme in the elderly.

BMJ Case Rep 2017 Jun 13;2017. Epub 2017 Jun 13.

Department of Neurosurgery, Leeds Teaching Hospitals, Leeds, UK.

Spinal glioblastoma multiforme (GBM) is uncommon, and its diagnosis may be challenging. This is especially true in the elderly population. Best management strategy remains to be defined. Read More

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http://dx.doi.org/10.1136/bcr-2016-217742DOI Listing
June 2017
3 Reads

Endoscopic Treatment of an Adult with Tegmental Astrocytoma Accompanied by Cerebrospinal Fluid Dissemination.

J Korean Neurosurg Soc 2017 May 1;60(3):375-379. Epub 2017 May 1.

Beijing Neurosurgical Institute, Beijing, China.

Midbrain gliomas are relatively rare neoplasms with a generally benign prognosis, with dissemination or metastasis not previously reported. We describe here a woman, in whom magnetic resonance imaging scans showed hydrocephalus and a tegmental lesion in the upper aqueduct. Endoscopic third ventriculostomy and biopsy were performed; during surgery, a second small lesion was observed in the infundibular recess. Read More

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http://dx.doi.org/10.3340/jkns.2014.0808.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426453PMC
May 2017
20 Reads

Adult pilocytic astrocytoma of conus medullaris: clinical considerations and review of the literature.

CNS Oncol 2017 04;6(2):107-110

Department of Neurosurgery, Hospital Santa Maria, Centro Hospitalar Lisboa Norte, Lisboa, Portugal.

Astrocytomas are responsible for 30% of all primitive intramedullary tumors with cervicothoracic predominance. However, only about one hundred cases of intramedullary pilocytic astrocytomas were described. The authors described the case of a 69 year-old patient presenting with a broad-base gait, bilateral pain and dysesthesia of inferior limbs with a diagnosis of an intra-axial cystic lesion centered to the conus medullaris, diagnosed as pilocytic astrocytoma of conus medullaris (PACM) after surgery. Read More

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http://dx.doi.org/10.2217/cns-2016-0030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020877PMC
April 2017
1 Read

Primary spinal glioblastoma multiforme: A case report and review of the literature.

Medicine (Baltimore) 2017 Apr;96(16):e6634

Department of Neurosurgery, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.

Rationale: Primary spinal glioblastoma multiforme (GBM) is a rare clinical entity with an aggressive course and an invariably dismal prognosis. Its clinical characteristics, radiologic and pathologic findings, and treatment protocols have been discussed in a few cases.

Patient Concerns: A 15-year-old female was admitted to the neurology department with a chief complaint of progressive numbness and weakness in her left upper extremity for 3 months and neck pain for 1 month. Read More

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https://www.thieme-connect.com/products/ejournals/pdf/10.105
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http://Insights.ovid.com/crossref?an=00005792-201704210-0004
Publisher Site
http://dx.doi.org/10.1097/MD.0000000000006634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406076PMC
April 2017
2 Reads

Glioblastoma multiforme in conus medullaris with intracranial metastasis after postoperative adjuvant therapy.

Medicine (Baltimore) 2017 Mar;96(13):e6500

aDepartment of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, No. 1 Shuaifuyuan, Dongcheng District, Beijing, P.R. China bDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Harvard University, MA cDepartment of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, No. 1 Shuaifuyuan, Dongcheng District, Beijing, P.R. China.

Spinal glioblastoma multiforme is not common among spinal cord tumors. According to our literature review, only 27 cases originating from the conus medullaris were reported. We herein reported a case of a 10-year-old child diagnosed with glioblastoma multiforme. Read More

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http://dx.doi.org/10.1097/MD.0000000000006500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380283PMC
March 2017
11 Reads

Axial MR diffusion tensor imaging and tractography in clinical diagnosed and pathology confirmed cervical spinal cord astrocytoma.

J Neurol Sci 2017 Apr 14;375:43-51. Epub 2017 Jan 14.

Department of Neurosurgery, Changgung Hospital, Medical Center, Tsinghua University, Beijing 102218, PR China. Electronic address:

Objective: To evaluate the diffusion tensor imaging (DTI) and diffusion tensor tractography (DTT) features of cervical spinal cord astrocytoma.

Methods: Eleven patients with cervical spinal cord astrocytomas and 10 healthy volunteers were recruited in this study. Conventional magnetic resonance imaging (MRI) and axial DTI were performed on a 3. Read More

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http://dx.doi.org/10.1016/j.jns.2017.01.044DOI Listing
April 2017
18 Reads

Midbrain Gliofibroma Presenting in Adulthood following "Cure" of a Childhood Intraventricular Pilocytic Astrocytoma.

Pediatr Neurosurg 2017 1;52(3):151-154. Epub 2017 Mar 1.

School of Medicine, University of Liverpool, Liverpool, UK.

Introduction: Gliofibromas are rare biphasic tumours with a good prognosis that usually occur in childhood. Rare adult spinal cases have been treated with radiotherapy. This report describes the case of a gliofibroma occurring in a young adult 10 years after treatment for a childhood pilocytic astrocytoma. Read More

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http://dx.doi.org/10.1159/000455920DOI Listing
May 2018
10 Reads

Unusual Occurrence of Multifocal Desmoplastic Infantile Astrocytoma: A Case Report and Review of the Literature.

Pediatr Neurosurg 2017 22;52(3):173-180. Epub 2017 Feb 22.

Department of Neurosurgery, Kidwai Memorial Institute of Oncology, Bengaluru, India.

Desmoplastic infantile gliomas are rare, benign tumors of the early infancy period. Two histological subtypes - desmoplastic infantile astrocytoma (DIA) and desmoplastic infantile ganglioglioma - have been described. The characteristic features of DIAs are lobar location, glial histology, and excellent prognosis after complete surgical excision. Read More

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https://www.karger.com/Article/FullText/455926
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http://dx.doi.org/10.1159/000455926DOI Listing
May 2018
1 Read

Multicentric Spinal Cord Glioblastoma.

World Neurosurg 2017 Apr 13;100:707.e11. Epub 2017 Jan 13.

Department of Pathology, National Rehabilitation Institute, México City, México.

A 40-year-old man was referred to our center with a 4-month history of progressive quadriparesis. Previous brain imaging revealed no abnormality. Magnetic resonance imaging (MRI) with contrast of the cervicothoracic spine revealed 2 heterogeneously enhancing lesions at the level of C3-C5 and T2-T4 (A); T1- and T2-weighted MRI showed hypointense and hyperintense lesions, respectively, which is characteristic of spinal cord astrocytoma (B and C). Read More

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http://dx.doi.org/10.1016/j.wneu.2017.01.006DOI Listing
April 2017
3 Reads

Distant spread of a supratentorial glioblastoma to the spinal cord.

J Clin Neurosci 2017 Apr 12;38:56-57. Epub 2017 Jan 12.

Department of Cancer Imaging, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Monash Imaging, Monash Health, Clayton, VIC, Australia. Electronic address:

Extracranial spread from a glioblastoma is rare. We present a case of a 48year-old man with a previously radiologically-stable left temporal lobe glioblastoma presenting with symptoms referrable to the spinal cord. MRI revealed a spinal cord lesion, with the differential including transverse myelitis and tumour. Read More

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http://dx.doi.org/10.1016/j.jocn.2016.11.010DOI Listing
April 2017
3 Reads

Canine spinal cord glioma.

J Vet Diagn Invest 2017 Jan 20;29(1):126-132. Epub 2016 Dec 20.

Department of Pathology and Athens Veterinary Diagnostic Laboratory (Rissi, Burnum) and Neurology and Neurosurgery Service, University of Georgia College of Veterinary Medicine, Athens, GA (Barber).

Spinal cord glioma is uncommonly reported in dogs. We describe the clinicopathologic and diagnostic features of 7 cases of canine spinal cord glioma and briefly review the veterinary literature on this topic. The median age at presentation was 7. Read More

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http://dx.doi.org/10.1177/1040638716673127DOI Listing
January 2017
7 Reads

Spinal metastases of glioblastoma multiforme in a patient with polyneuropathy.

Natl Med J India 2016 Jul-Aug;29(4):246

Department of Neurology, Wroclaw Medical University, 50-556 Wroclaw, Poland.

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January 2018
4 Reads

BRAF-Mutated Pleomorphic Xanthoastrocytoma of the Spinal Cord with Eventual Anaplastic Transformation.

World Neurosurg 2017 Feb 10;98:871.e9-871.e15. Epub 2016 Dec 10.

Department of Neurological Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA. Electronic address:

Background: Pleomorphic xanthoastrocytoma (PXA) is an uncommon, primary neoplasm of the central nervous system with a relatively favorable prognosis. Most patients are managed with surgery alone and experience significant long-term survival. PXAs occur most commonly along the superficial surfaces of the temporal lobes. Read More

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http://dx.doi.org/10.1016/j.wneu.2016.11.148DOI Listing
February 2017
1 Read

Rosette-Forming Glioneuronal Tumor Originating From the Spinal Cord: Report of 2 Cases and Literature Review.

World Neurosurg 2017 Feb 30;98:875.e1-875.e7. Epub 2016 Nov 30.

Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; China National Clinical Research Center for Neurological Diseases, Beijing, China. Electronic address:

Rosette-forming glioneuronal tumor (RGNT) is a recently recognized and rarely encountered tumor occurring in the fourth ventricle. RGNT was first described as a new entity for the distinct clinicopathologic features by Komori et.al. Read More

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http://dx.doi.org/10.1016/j.wneu.2016.11.109DOI Listing
February 2017
15 Reads

Spinal diffusion tensor tractography for differentiation of intramedullary tumor-suspected lesions.

Eur J Radiol 2016 Dec 17;85(12):2275-2280. Epub 2016 Oct 17.

Department of Neuroradiology, University Medical Center Freiburg, Breisacher Straße 64, 79106 Freiburg, Germany.

Background And Purpose: Primary MRI diagnosis of spinal intramedullary tumor-suspected lesions can be challenging and often requires spinal biopsy or resection with a substantial risk of neurological deficits. We evaluated whether Diffusion Tensor Imaging (DTI) tractography can facilitate the differential diagnosis.

Materials And Methods: Twenty-five consecutive patients with an intramedullary tumor-suspected lesion considered for spinal surgery were studied with a Diffusion-weighted multi-shot read out segmented EPI sequence (RESOLVE). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0720048X163032
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http://dx.doi.org/10.1016/j.ejrad.2016.10.018DOI Listing
December 2016
18 Reads

Imaging of Orthotopic Glioblastoma Xenografts in Mice Using a Clinical CT Scanner: Comparison with Micro-CT and Histology.

PLoS One 2016 9;11(11):e0165994. Epub 2016 Nov 9.

Department of Neuroradiology, University Medical Center of the Johannes Gutenberg University Mainz, 55131, Mainz, Germany.

Purpose: There is an increasing need for small animal in vivo imaging in murine orthotopic glioma models. Because dedicated small animal scanners are not available ubiquitously, the applicability of a clinical CT scanner for visualization and measurement of intracerebrally growing glioma xenografts in living mice was validated.

Materials And Methods: 2. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0165994PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102379PMC
July 2017
21 Reads

Granular cell tumors in the central nervous system: a report on eight cases and a literature review.

Br J Neurosurg 2016 Dec 18;30(6):611-618. Epub 2016 May 18.

a Department of Neurosurgery , Beijing Tian Tan Hospital, Capital Medical University , Beijing , PR China.

Objective: Granular cell tumors (GCTs) in the central nervous system (CNS) are extremely rare. We report here a series of eight GCTs at various locations in the CNS and provide a full review of the published literature.

Methods: Eight patients with pathologically confirmed GCT in the CNS were retrospectively reviewed. Read More

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https://www.tandfonline.com/doi/full/10.1080/02688697.2016.1
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http://dx.doi.org/10.1080/02688697.2016.1181152DOI Listing
December 2016
31 Reads