Search Our Scientific Publications & Authors

Folia Neuropathol 2022 ;60(2):261-265

Zhuji Hospital Affiliated of Shaoxing University, China.

Spontaneous spinal epidural haematoma (SSEH) is a rare disease that requires emergency decompression or haematoma evacuation to prevent permanent neurological deficits. Hemiparesis is an extremely rare presentation of SSEH, commonly misdiagnosed as stroke. With the help of case studies and references, this paper comprehensively discusses the effective methods to distinguish SSEH from stroke and provides theoretical support and ideas for rapid and accurate identification of SSEH. Read More

J Neurosci Rural Pract 2022 Jul 13;13(3):537-540. Epub 2022 Jun 13.

Department of Radiology, University of Florida Jacksonville, Jacksonville, Florida.

 Secondary peripheral nerve injuries remain a significant perioperative problem due to patient positioning and contribute to reduced patient quality of life and exacerbated professional liability. Comorbidities and concomitant lesions can further elicit these injuries in patients undergoing spinal surgeries.  We report a case of a 70-year-old male polytrauma patient presenting with a left first-rib fracture and an adjacent hematoma around the brachial plexus without preoperative deficits. Read More

J Nepal Health Res Counc 2022 Jun 3;20(1):272-275. Epub 2022 Jun 3.

Civil Service Hospital, Minbhawan, Nepal.

Entrapment abdominal neuropathy is not a common diagnosis in our context. Chronic Abdominal wall pain is often mistaken for gastritis, gynecological issue, thoracic spinal radiculopathy, rectus sheath hematoma, abdominal muscle injury or psychiatric disorder. Anterior cutaneous nerve entrapment syndrome is one of the frequent causes of abdominal wall pain occurring due to trapped thoracic intercostal nerves between abdominal muscles. Read More

Medicine (Baltimore) 2022 Aug;101(31):e30012

Department of Neurosurgery, Taizhou People's Hospital affiliated to Nanjing Medical University, Hailing District, Taizhou, Jiangsu, China.

Rationale: Subdural anaplastic large-cell lymphoma (SALCL) is an extremely rare subtype of primary central nervous system (CNS) lymphoma. Here, we report a very rare subdural lymphoma case, which was misdiagnosed as a subacute epidural hematoma based on the radiological examination.

Patient Concerns: We present the case of an 82-year-old patient who presented with a 2-day history of headache and consciousness disorder following head injury. Read More

World Neurosurg 2022 Aug 1. Epub 2022 Aug 1.

Division of Neurosurgery, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong.

Aim: This study aims to identify independent factors associated with cervical spinal injuries in head-injured patients. The extent of injuries to other body parts was assessed by the Abbreviated Injury Scale (AIS) and was included in the analysis.

Methods: Consecutive head-injured patients admitted via the Emergency Department from 1 January 2014 to 31 December 2016 were retrospectively reviewed. Read More

Anaesthesiologie 2022 May 30. Epub 2022 May 30.

Universitätsklinik für Anästhesiologie und Intensivtherapie, Universitätsklinikum Magdeburg A.ö.R. Otto-von-Guericke-Universität Magdeburg, Leipziger Str. 44, Magdeburg, Deutschland.

Ullrich congenital muscular dystrophy (UCMD) is a rare disease caused by mutations in the COL6A1, COL6A2 or COL6A3 genes leading to deficiency of collagen VI in extracellular matrices (ECM). Patients present with generalized muscle weakness, predominantly in the trunk and proximal limbs, hyperlaxity of distal joints, spinal rigidity, scoliosis and various proximal joint contractures, loss of ambulation by 9-11 years of age and progressive respiratory dysfunction. About 50% of the patients require noninvasive ventilation (NIV) by the age of 11-12 years. Read More

Rev Med Liege 2022 Jul;77(7-8):473-476

Service d'Anesthésie-Réanimation, CHU Liège, Belgique.

We report a case of cerebral hypotension due to an idiopathic cerebral spinal fluid leak associated with bilateral sub-dural hygromas. The symptoms were not relieved despite of multiple lumbar, thoracic and cervical «blind» blood patches. The check-up led to a scopic controlled cervical blood patch directly on the leak by a paramedian approach with a complete clinical and radiological response to treatment. Read More

Anaesth Rep 2022 Jul-Dec;10(2):e12181. Epub 2022 Jul 30.

Department of Anaesthesiology Penafiel Hospital Centre Porto Portugal.

We report a case of a previously healthy patient who developed a vertebral canal haematoma in the subarachnoid and subdural spaces after a spinal puncture for elective caesarean section. Vertebral canal haematomas are rare. There are different mechanisms for haematoma formation, but coagulation disturbances and trauma, most often due to needle punctures, are the most important. Read More

Spine (Phila Pa 1976) 2022 Aug 2. Epub 2022 Aug 2.

Department of Orthopaedic Surgery, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.

Study Design: Retrospective case series.

Objective: The purpose of this study was to investigate the outcome of multilevel posterior decompression surgery for degenerative lumbar spinal stenosis (LSS) compared with single-level surgery.

Summary Of Background Data: The clinical outcomes of multilevel decompression surgery are still controversial because previous studies have not been designed to randomize or adjust the patient background. Read More

Ned Tijdschr Geneeskd 2022 07 19;166. Epub 2022 Jul 19.

St. Antonius Ziekenhuis, Nieuwegein. Afd. Neurologie.

Three patients with acute severe neck pain, presented with and without neurological deficits. One patient had severe neck pain followed by autonomic dysfunction, aphagia and dysarthria. She had an vertebrobasilar infarction due to the etiology of a dissection of both vertebral arteries. Read More

N Am Spine Soc J 2022 Sep 12;11:100141. Epub 2022 Jul 12.

Department of Orthopedic Surgery, University of Kansas Medical Center, Kansas City, United States.

Background: Prophylactic anticoagulation is commonly used following operative treatment of spinal fractures to prevent Venous Thromboembolism (VTE) but carries a risk of bleeding complications. The purpose of the study was to compare VTE and bleeding complications for MID (≤72h) versus LATE (>72h) chemoprophylaxis timing after spinal fracture operative intervention.

Methods: This is a retrospective review of patients treated for spinal fractures that received anticoagulation chemoprophylaxis between May 2015 and June 2019. Read More

Spine J 2022 Jul 22. Epub 2022 Jul 22.

Department of Orthopedics, Peking University Third Hospital, No. 49 North Garden Road, Haidian District, Beijing 100191, China; Engineering Research Center of Bone and Joint Precision Medicine, No. 49 North Garden Road, Haidian District, Beijing 100191, China; Beijing Key Laboratory of Spinal Disease Research, No. 49 North Garden Road, Haidian District, Beijing 100191, China. Electronic address:

Background Context: Unplanned reoperation, a quality indicator in spine surgery, has not been sufficiently investigated in a large-scale, single-center study.

Purpose: To assess the incidences, causes, and risk factors of unplanned reoperations within 30 days of spine surgeries in a single-center study.

Study Design: Retrospective observational study. Read More

Cureus 2022 Jun 17;14(6):e26028. Epub 2022 Jun 17.

Department of Orthopaedic Surgery, Kyushu University Hospital, Fukuoka, JPN.

Spinal subdural hematoma (SSDH) associated with cranial subdural hematoma (CSDH) is considered extremely rare and the etiology remains unclear. Herein, we report two cases of spontaneous SSDH concomitant with CSDH, with no history of trauma. First, a healthy 35-year-old woman suffered from left leg pain following a headache caused by acute CSDH. Read More

Surg Neurol Int 2022 23;13:259. Epub 2022 Jun 23.

Cedars-Sinai Medical Center, Spine Center, Los Angeles, California, United States.

Background: Dabigatran is an anticoagulant (novel oral anticoagulant) that is a direct thrombin inhibitor and only recently has a reversal agent, idarucizumab, been made available (2015).

Case Description: An 86-year-old male taking dabigatran for atrial fibrillation, acutely presented with the spontaneous onset of neck pain and quadriparesis. When the MRI demonstrated a C2-T2 spinal epidural hematoma, the patient was given the reversal agent idarucizumab. Read More

J Neurosurg Case Lessons 2021 Sep 27;2(13):CASE21211. Epub 2021 Sep 27.

Division of Neurosurgery, Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada; and.

Background: Atlantoaxial sublaminar wiring has many known complications related to hardware failure, but intracranial hemorrhage is a rare complication.

Observations: A 61-year-old female patient with prior atlantoaxial sublaminar wiring for odontoid fracture nonunion experienced decreased level of consciousness due to a subarachnoid and subdural hemorrhage of the posterior fossa with intraventricular extension and hydrocephalus. Rupture of the sublaminar wire with intramedullary protrusion was the cause of the hemorrhage. Read More

Int Orthop 2022 Jul 19. Epub 2022 Jul 19.

Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto, 606-8507, Japan.

Purpose: This study aimed to elucidate the severity of neurological deficits in a large series of patients with acute spontaneous spinal epidural haematoma (SSEH) using magnetic resonance imaging (MRI).

Methods: We included 57 patients treated for acute SSEH at 11 institutions and retrospectively analysed their demographic and MRI data upon admission. We investigated MRI findings, such as the haematoma length and canal occupation ratio (COR). Read More

Rev Esp Cir Ortop Traumatol 2022 Jul 16. Epub 2022 Jul 16.

Departamento de Ortopedia y Traumatología, Instituto de Ortopedia "Carlos Ottolenghi", Hospital Italiano de Buenos Aires, Buenos Aires, Argentina. Electronic address:

Introduction And Objectives: Spinal metastases (SM) account for 5-30% of patients with cancer, causing pain, deformity and/or neurological deficit. Postoperative complications are a concerning subject and wound-related complications (WRC) may delay adjuvant treatment. The objective of this study was to analyze the incidence of WRC in patients with SM that underwent surgical treatment as well as possible risk factors related to the occurrence of complications. Read More

JBJS Case Connect 2022 Jul 18;12(3). Epub 2022 Jul 18.

Department of Orthopedic Surgery, the Jikei University School of Medicine, Tokyo, Japan.

Case: A 73-year-old woman presented with degenerative kyphoscoliosis. Radiographs revealed sagittal and coronal imbalance with lumbar spinal stenosis. Extreme lateral interbody fusion (XLIF) was performed in the first stage of 2-stage surgery, and a closed-suction drainage tube was placed in the retroperitoneal cavity. Read More

Comput Math Methods Med 2022 4;2022:6762530. Epub 2022 Jul 4.

Department of Spine, General Hospital of Northern Theater Command, China.

Objective: Comparison of the clinical and radiological effects of precise unilateral puncture pathway prepared by preoperative CT data and traditional unilateral puncture pathway in PVP administration for the treatment of osteoporotic vertebral compression fractures. PVP is a commonly used vertebral augmentation operation for the treatment of painful spinal compression fractures. A percutaneous unilateral approach is routinely used to get access to the vertebral body. Read More

Iowa Orthop J 2022 06;42(1):83-88

Orthopaedic Trauma Department, University Hospitals Cleveland Medical Center Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.

Background: Several strategies exist to prevent venous thromboembolism (VTE) in operative pelvic and acetabular fractures, however literature lacks consensus on the optimal thromboprophylaxis. Even more debated, and perhaps controversial, is whether aspirin provides adequate thromboprophylaxis in the setting of these injuries. The primary objective was to evaluate the efficacy of aspirin in the prevention of venous thromboembolism (VTE) events, including deep vein thrombosis (DVT) and pulmonary embolism (PE) in operative pelvic and acetabular fractures compared to other anticoagulants. Read More

Eur Spine J 2022 Jul 10. Epub 2022 Jul 10.

Department of Orthopaedics, Beijing Key Laboratory of Spinal Disease Research, Peking University Third Hospital, Beijing, People's Republic of China.

Purpose: The goal of this research is to explore the incidence and risk factors of symptomatic spinal epidural hematoma (SSEH) following cervical spine surgery.

Methods: Patients with SSEH from January 2009 to February 2019 were identified as hematoma group. Two control subjects without SSEH were randomly selected for each patient in SSEH group as control group. Read More

Ann Palliat Med 2022 Jun;11(6):2025-2032

Department of Orthopedics, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, China.

Background: Cervical spondylotic myelopathy (CSM) is a common cause of neurological morbidity, which can have an impact on quality of life. Symptomatic postoperative spinal epidural hematoma (SPSEH) is a rare condition, but can cause permanent neurological deficits and disability if not managed properly. However, there are limited studies on the outcomes of SPSEH after anterior cervical discectomy and fusion (ACDF) and anterior cervical corpectomy and fusion (ACCF) were performed for 2-level CSM. Read More

Asian J Surg 2022 Jul 5. Epub 2022 Jul 5.

Department of Spinal Surgery, Zheng Zhou Orthopaedics Hospital, Zhengzhou, China. Electronic address:

Objective: Spinal cord injury is a common occurrence during spinal surgery. In this study, we proposed a zoning laminectomy, which could reduce the incidence of nerve injury. We also discussed the safety and clinical efficacy of the zoning laminectomy for thoracic ossification of the ligamentum flavum (TOLF). Read More

Spine Surg Relat Res 2022 14;6(3):240-246. Epub 2021 Dec 14.

Department of Orthopedic Surgery, Kumamoto Chuo Hospital, Kumamoto, Japan.

Introduction: More spinal surgeries are being performed in patients taking low-dose aspirin for primary and secondary prevention of cardiovascular and cerebrovascular ischemic disease. However, there are no recommended guidelines for perioperative aspirin use in patients undergoing spinal surgery. This study evaluated the perioperative effect of continued low-dose aspirin on cervical laminoplasty. Read More

Trauma Case Rep 2022 Aug 28;40:100668. Epub 2022 Jun 28.

Department of Neurosurgery, University of California San Francisco, San Francisco, CA, United States of America.

Background: Traumatic subdural hematomas (SDH) can have devastating neurologic consequences. Acute-on-chronic SDHs are more frequent in the elderly, who have increased comorbidities and perioperative risks. The subdural evacuation port system (SEPS) procedure consists of a twist drill hole connected to a single drain on suction, which can be performed at bedside to evacuate SDHs without requiring general anesthesia. Read More

Asian Spine J 2022 Jul 4. Epub 2022 Jul 4.

Spine Surgery, Nanoori Gangnam Hospital, Seoul, Korea.

Study Design: Retrospective cohort study.

Purpose: To evaluate the clinical and radiological effects of epidural fluid hematoma in the medium term after lumbar endoscopic decompression.

Overview Of Literature: There is limited literature comparing the effect of postoperative epidural fluid hematoma after uniportal endoscopic decompression. Read More

Case Rep Obstet Gynecol 2022 23;2022:3097949. Epub 2022 Jun 23.

Department of Endocrinology, Diabetes and Metabolism, Walter Reed National Military Medical Center, Bethesda, USA.

Pituitary apoplexy can occur postpartum, and subdural hematoma following epidural anesthesia is a rare complication. Cooccurrence of these two complications is extremely rare and has not been previously reported in the literature. In this article, we present a case of pituitary apoplexy along with intracranial subdural hematoma happening two days after spinal anesthesia for cesarean section. Read More

Clin Neurol Neurosurg 2022 Aug 6;219:107319. Epub 2022 Jun 6.

Department of Neurosurgery, University of Cincinnati School of Medicine, USA.

Background: While several studies explore the impact of smoking tobacco on spinal fusion outcomes, there is a paucity of literature on the influence of modern smoking cessation therapies on such outcomes in patients undergoing anterior cervical discectomy and fusion (ACDF).

Objective: Our study explores the outcomes of single-level ACDF surgery in nonsmokers, active smokers, and smokers undergoing cessation therapy.

Methods: MARINER30, an all-payer claims database, was utilized to identify patients undergoing single-level ACDF between 2010 and 2019. Read More

Cureus 2022 May 27;14(5):e25404. Epub 2022 May 27.

Department of Orthopedic Surgery, Kyushu Central Hospital of the Mutual Aid Association of Public School Teachers, Fukuoka, JPN.

Purpose Symptomatic postoperative spinal epidural hematoma (POSEH) is a complication of spine surgery that occurs infrequently but may cause ongoing serious neurological damage. Due to the narrow entry portal, the risk of hematoma is increased after microendoscopic laminectomy (MEL) compared with conventional open surgery, and the risk might be even higher for multivertebral MEL (m-MEL). The purpose of this study was to clarify the factors affecting the development of POSEH after m-MEL and identify the optimal order for the decompression of vertebral bodies. Read More

JBJS Case Connect 2022 Apr 4;12(2). Epub 2022 May 4.

Washington State University, Elson S. Floyd College of Medicine, Spokane, Washington.

Case: A 71-year-old woman with a 2-year history of spondylosis and radiculopathy presented with progressively worsening cervical spine pain and neurological dysfunction for 2 years. The patient developed posterior reversible encephalopathy syndrome (PRES) after postoperative hematoma in the retroesophageal and retropharyngeal areas. This occurred status post anterior cervical diskectomy and fusion (ACDF) of C4-C6. Read More