374,395 results match your criteria Spinal Dysraphism Myelomeningocele


Assessment of Postoperative Outcomes in Spinal Epidural Abscess Following Surgical Decompression.

Spine J 2018 Dec 8. Epub 2018 Dec 8.

Center for Spine Health, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, Ohio, 44195, USA; Department of Neurosurgery, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, Ohio, 44195, USA; Cleveland Clinic Lerner College of Medicine, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, Ohio, 44195, USA. Electronic address:

Background Context: A spinal epidural abscess (SEA) is a serious condition that may be managed with antibiotics alone or with decompressive surgery combined with antibiotics.

Purpose: The objectives of this study were to assess the clinical outcomes of SEA after surgical management and to identify the patient-level factors that are associated with outcomes following surgical decompression and removal of SEA.

Study Design/setting: Retrospective chart review analysis. Read More

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December 2018

Surgical Risk Stratification Based on Preoperative Risk Factors in Adult Spinal Deformity.

Spine J 2018 Dec 8. Epub 2018 Dec 8.

Department of Orthopedic Surgery, Keio University School of Medicine; Keio Spine Research Group. Electronic address:

Background Context: Corrective surgery for adult spinal deformity (ASD) improves health-related quality of life but has high complication rates. Predicting a patient's risk of perioperative and late postoperative complications is difficult, although several potential risk factors have been reported.

Purpose: To establish an accurate, ASD-specific model for predicting the risk of postoperative complications, based on baseline demographic, radiographic, and surgical invasiveness data in a retrospective case series. Read More

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December 2018

Histological and histochemical characterisation of glands associated with the feeding appendages of Argulus foliaceus (Linnaeus, 1758).

Parasitol Int 2018 Dec 8. Epub 2018 Dec 8.

Institute of Aquaculture, University of Stirling, Stirling, UK.

Argulus foliaceus (Linnaeus, 1758) is a member of the branchiuran family Argulidae, a group comprising parasitic "fish lice". A. foliaceus is distributed worldwide and causes major economic impacts for cultured freshwater fish globally. Read More

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December 2018

Sacral neuromodulation: standardized tined lead implantation technique: two-year clinical outcome and sensory response upon lead stimulation comparing the use of the curved versus straight stylet.

BJU Int 2018 Dec 11. Epub 2018 Dec 11.

Department of Urology, Antwerp University Hospital, Edegem, Belgium.

Objectives: To assess clinical follow-up data over 24 months using the standardized tined lead implantation technique, comparing the use of the curved vs straight stylet.

Patients And Methods: Single tertiary center, prospective study (August 2013 - June 2015) involving 40 patients with overactive bladder and 15 with non-obstructive urinary retention refractory to first-line treatment.

Primary Outcome: successful tined lead procedure; intention to treat analysis at 12 and 24 months. Read More

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December 2018

Magnetic resonance imaging in enterovirus-71, myelin oligodendrocyte glycoprotein antibody, aquaporin-4 antibody, and multiple sclerosis-associated myelitis in children.

Dev Med Child Neurol 2018 Dec 10. Epub 2018 Dec 10.

Neuroimmunology Group, Institute for Neuroscience and Muscle Research, The Kids Research Institute, Children's Hospital at Westmead, Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.

Aim: We used magnetic resonance imaging (MRI) to compare the neuroimaging of children with their first episode of clinical enterovirus 71-associated transverse myelitis (EV71-TM), myelin oligodendrocyte glycoprotein antibody positive transverse myelitis (MOG-TM), aquaporin-4 antibody positive transverse myelitis (AQP4-TM), transverse myelitis in multiple sclerosis (MS-TM), and unclassified transverse myelitis (UNC-TM).

Method: We performed a retrospective blinded radiological assessment and compared the neuroimaging of 52 children (32 females, 20 males; mean age 9y 8mo, SD 5y 5mo, range 5mo-17y) presenting with their first episode of myelitis caused by EV71-TM (n=11), MOG-TM (n=10), AQP4-TM (n=9), MS-TM (n=13), and UNC-TM (n=9).

Results: In the EV71-TM group, lesions were distributed throughout the cord and enhancement of nerve roots (ventral and dorsal) was common. Read More

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December 2018

Trial Versus No Trial of Spinal Cord Stimulation for Chronic Neuropathic Pain: Cost Analysis in United Kingdom National Health Service.

Neuromodulation 2018 Dec 10. Epub 2018 Dec 10.

Basildon and Thurrock University Hospitals, Basildon, UK.

Objectives: The aim of the current project was to evaluate the spinal cord stimulation (SCS) screening trial success rate threshold to obtain the same cost impact across two identical sets of patients following either a prolonged screening trial prior to implantation strategy or a full implant without a screening trial.

Materials And Methods: A cost impact analysis was carried out from a health care perspective and considered trial to implant rates reported in the literature. Items of resource use were costed using national averages obtained from the National Health Service (NHS) reference cost data base. Read More

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December 2018

Organisation of health services for preventing and treating pressure ulcers.

Cochrane Database Syst Rev 2018 Dec 9;12:CD012132. Epub 2018 Dec 9.

School of Medicine, Royal College of Surgeons in Ireland, 121 St. Stephens Green, Dublin, Ireland, 2.

Background: Pressure ulcers, which are a localised injury to the skin, or underlying tissue, or both, occur when people are unable to reposition themselves to relieve pressure on bony prominences. Pressure ulcers are often difficult to heal, painful, expensive to manage and have a negative impact on quality of life. While individual patient safety and quality care stem largely from direct healthcare practitioner-patient interactions, each practitioner-patient wound-care contact may be constrained or enhanced by healthcare organisation of services. Read More

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December 2018
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Propofol partially attenuates complete freund's adjuvant-induced neuroinflammation through inhibition of the ERK1/2/NF-κB pathway.

J Cell Biochem 2018 Dec 9. Epub 2018 Dec 9.

Department of Anesthesiology, Quzhou Hospital of Zhejiang University School of Medicine, Quzhou, China.

Peripheral inflammation in male C57BL/6 mice was induced by intraplantar injection of 20 μL complete freund's adjuvant (CFA) in the left hind paw. Mice were randomly divided into three groups: Sham, CFA, and propofol+CFA. Mechanical allodynia was assessed by von Frey analysis, and heat hyperalgesia was detected by exposure of the plantar surface to a beam of radiant heat. Read More

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December 2018

Gelatin-coating increases in-vivo bone formation capacity of three-dimensional 45S5-bioactive glass-based crystalline scaffolds.

J Tissue Eng Regen Med 2018 Dec 7. Epub 2018 Dec 7.

Institute of Biomaterials, University of Erlangen-Nuremberg, Erlangen, Germany.

Recent studies have demonstrated that surface characteristics, porosity, and mechanical strength of three-dimensional (3D) 45S5-type bioactive glass (BG)-based scaffolds are directly correlated with osteogenic properties. 3D-BG-scaffolds obtained from maritime natural sponges (MNS) as sacrificial templates exhibit the required morphological properties; however, no in-vivo data about the osteogenic features is available. In this study, uncoated (group A) and gelatin-coated (group B) crystalline MNS-obtained BG-scaffolds were evaluated mechanically and seeded with human mesenchymal stem cells prior to subcutaneous implantation in immunodeficient mice. Read More

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December 2018

Determinants for Meaningful Clinical Improvement of Pain and Health-Related Quality of Life After Spinal Cord Stimulation for Chronic Intractable Pain.

Neuromodulation 2018 Dec 10. Epub 2018 Dec 10.

Center for Applied Neuroscience (CeNAp), University Hospital (HU), Federal University of Santa Catarina State (UFSC), Florianópolis, SC, Brazil.

Objectives: Previous studies demonstrated significant improvement in mean pain scores and quality of life (QOL) scales in patients with chronic pain who underwent spinal cord stimulation (SCS). However, the number of individuals who experience relevant improvements in QOL, termed the meaningful clinical improvement (MCI), is not known. The present study investigated changes in pain measurements based on MCI after SCS. Read More

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December 2018

Expression of lamin A/C protein in degenerated human intervertebral disc.

Eur Rev Med Pharmacol Sci 2018 Nov;22(22):7607-7613

Department of Spine Surgery, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.

Objective: This study aimed to evaluate the expression characteristics of lamin A/C proteins in intervertebral disc degeneration (IVD) specimens from patients with different degeneration grades. Lamin A/C proteins have been shown to result in age-related changes in the osteoarticular system. However, the expression characteristics of these nuclear proteins in degenerated human IVD tissues have not been explored previously. Read More

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November 2018

LncRNA ZNF667-AS1 inhibits inflammatory response and promotes recovery of spinal cord injury via suppressing JAK-STAT pathway.

Eur Rev Med Pharmacol Sci 2018 Nov;22(22):7614-7620

Department of Spinal Surgery, the People's Hospital of Rizhao City, Rizhao, China.

Objective: The aim of this study was to explore the role of lncRNA ZNF667-AS1 in the recovery of spinal cord injury (SCI), and to investigate its underlying mechanism.

Materials And Methods: Mice were randomly assigned to the SCI group, the sham group and the lncRNA ZNF667-AS1 group, with 10 mice in each group. With Infinite Horizon device at a dose of 80 Kdyn, mice in the SCI group and the lncRNA ZNF667-AS1 group experienced SCI by an acute hit on the C5 spinous process. Read More

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November 2018

[Ultrasonography and image-guided injection techniques of the spinal column : Imaging is still the gold standard].

Authors:
F Faber

Schmerz 2018 Dec 10. Epub 2018 Dec 10.

Orthopädische Klinik, Universität Regensburg, Kaiser-Karl-V.-Allee 3, 93077, Bad Abbach, Deutschland.

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December 2018

Upregulation of UBAP2L in Bone Marrow Mesenchymal Stem Cells Promotes Functional Recovery in Rats with Spinal Cord Injury.

Curr Med Sci 2018 Dec 7;38(6):1081-1089. Epub 2018 Dec 7.

Department of Orthopaedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

Post-translational modifications of cellular proteins with ubiquitin or ubiquitin-like proteins regulate many cellular processes, such as cell proliferation, differentiation, apoptosis, signal transduction, intercellular immune recognition, inflammatory response, stress response, and DNA repair. Nice4/UBAP2L is an important member in the family of ubiquitin-like proteins, and its biological function remains unknown. This study aimed to investigate the effect of UBAP2L on spinal cord injury (SCI). Read More

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December 2018

Computer-assisted Surgery for Scaphoid Fracture.

Curr Med Sci 2018 Dec 7;38(6):941-948. Epub 2018 Dec 7.

Department of Hand Surgery, Beijing Jishuitan Hospital, Beijing, 100035, China.

The computer-assisted surgery (CAS) has significantly improved the accuracy, reliability and outcomes of traumatic, spinal, nerve surgery and many other operations with a less invasive way. The application of CAS for scaphoid fractures remains experimental. The related studies are scanty and most of them are cadaver researches. Read More

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December 2018

Unusual osteological findings in sacred relics from the LESJE monastery in central Serbia.

Forensic Sci Med Pathol 2018 Dec 7. Epub 2018 Dec 7.

School of Medicine, The University of Adelaide, and Forensic Science South Australia (FSSA), Level 2 Medical School North Building, Frome Road, Adelaide, South Australia, 5005, Australia.

An adult male skeleton was submitted to the Department of Anatomy at the University of Belgrade for evaluation. It was believed to represent the remains of a second to third century Christian saint from the Lesje Monastery in central Serbia. Examination of the remains revealed an old crush fracture of a thoracic vertebra and an unusual, probably congenital, malformation of the atlanto-occipital joint with deformation of the left occipital condyle and resultant narrowing of the foramen magnum. Read More

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December 2018

Future blood pressure monitoring for cesarean delivery.

Authors:
Yusuke Mazda

J Anesth 2018 Dec 10. Epub 2018 Dec 10.

Department of Anesthesia and Pain Management, Mount Sinai Hospital, University of Toronto, 500 University Avenue, Toronto, ON, M5G 1X5, Canada.

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December 2018

Connexin43 hemichannel block protects against the development of diabetic retinopathy signs in a mouse model of the disease.

J Mol Med (Berl) 2018 Dec 8. Epub 2018 Dec 8.

Buchanan Ocular Therapeutics Unit, Department of Ophthalmology and the New Zealand National Eye Centre, University of Auckland, Auckland, New Zealand.

Diabetic retinopathy (DR) is a vascular disease of the neuroretina characterised by hyperglycaemia and inflammation. Current DR therapies target late-stage vascular defects and there is evidence to suggest that they contribute to geographic atrophy and retinal ganglion cell death long term. Therefore, alternative treatments that target common upstream disease mechanisms are needed. Read More

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December 2018

Overexpression of SMN2 Gene in Motoneuron-Like Cells Differentiated from Adipose-Derived Mesenchymal Stem Cells by Ponasterone A.

J Mol Neurosci 2018 Dec 7. Epub 2018 Dec 7.

Applied Cell Sciences and Tissue Engineering Department, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Cell therapy and stem cell transplantation strategies have provided potential therapeutic approaches for the treatment of neurological disorders. Adipose-derived mesenchymal stem cells (ADMSCs) are abundant adult stem cells with low immunogenicity, which can be used for allogeneic cell replacement therapies. Differentiation of ADMSCs into acetylcholine-secreting motoneurons (MNs) is a promising treatment for MN diseases, such as spinal muscular atrophy (SMA), which is associated with the level of SMN1 gene expression. Read More

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December 2018

[The trend towards full-endoscopic decompression : Current possibilities and limitations in disc herniation and spinal stenosis].

Authors:
S Ruetten M Komp

Orthopade 2018 Dec 7. Epub 2018 Dec 7.

Zentrum für Wirbelsäulenchirurgie und Schmerztherapie, Zentrum für Orthopädie und Unfallchirurgie der St. Elisabeth Gruppe - Katholische Kliniken Rhein-Ruhr, St. Anna Hospital Herne/Universitätsklinikum, Marien Hospital Herne/Marien Hospital Witten, Hospitalstr. 19, 44649, Herne, Deutschland.

Background: The most frequent causes of degenerative constrictions of the spinal canal are disk herniations and spinal stenoses. The lumbar and cervical spine is the most affected.

Surgical Procedures: After conservative treatments have been exhausted, surgical intervention may be necessary. Read More

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December 2018

Intrasubject repeatability of in vivo intervertebral motion parameters using quantitative fluoroscopy.

Eur Spine J 2018 Dec 8. Epub 2018 Dec 8.

Faculty of Science and Technology, Bournemouth University, Bournemouth, UK.

Purpose: In vivo quantification of intervertebral motion through imaging has progressed to a point where biomarkers for low back pain are emerging. This makes possible deeper study of the condition's biometrics. However, the measurement of change over time involves error. Read More

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December 2018

Therapeutic abortion and ectopic pregnancy: alternative sources for fetal stem cell research and therapy in Iran as an Islamic country.

Cell Tissue Bank 2018 Dec 7. Epub 2018 Dec 7.

Cell Therapy and Regenerative Medicine Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

Regenerative medicine as a background of stem cell research and therapy has a long history. A wide variety of diseases including Parkinson's disease, heart diseases, multiple sclerosis, spinal cord injury, diabetes mellitus and etc. are candidate to be treated using different types of stem cells. Read More

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December 2018
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Spinal cord ultrasonography of the newborn.

J Ultrasound 2018 Dec 7. Epub 2018 Dec 7.

UOC Radiologia e Neuroradiologia, Dipartimento di diagnostica per immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, L.go F. Vito 1, 00168, Rome, Italy.

Ultrasound represents the first-line survey for the assessment of spinal cord development abnormalities. In fact, within 6 months of life, the non-ossification of neuronal arcs provides an excellent acoustic window that allows a detailed depiction of the spinal canal, its content and of the surrounding soft tissues. Nevertheless, an accurate ultrasound examination requires a complete knowledge of the anatomy, the condition of normality, the frequent anatomical variants and the main pathologies involved. Read More

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December 2018

Estimation of the number of feeding arteries of spinal arteriovenous malformations by using three-dimensional digital subtraction angiography.

Eur Spine J 2018 Dec 10. Epub 2018 Dec 10.

Department of Neurosurgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

Purpose: Spinal angiography is the gold standard for evaluation or diagnosis of spinal arteriovenous malformations (AVMs). However, some feeding arteries might be overlooked when multiple feeders exist. This study aimed to retrospectively review cases of spinal intra-dural AVMs, which were identified by three-dimensional digital subtraction angiography (3D-DSA), and attempted to estimate the number of feeding arteries. Read More

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December 2018

Letter: Steroid Use Associated With Increased Odds of 30-Day Mortality in Surgical Patients With Metastatic Spinal Tumors in the Setting of Disseminated Disease.

Neurosurgery 2018 Dec 11. Epub 2018 Dec 11.

Spine Research Group Montefiore Medical Center/Albert Einstein College of Medicine Bronx, New York.

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December 2018

Growth of Lumbosacral Perineural (Tarlov) Cysts: A Natural History Analysis.

Neurosurgery 2018 Dec 11. Epub 2018 Dec 11.

Department of Neurosurgery, University of Pennsylvania, Philadelphia, Pennsylvania.

Background: Tarlov cysts (TC) are commonly found spinal perineural cysts. Symptomatic TCs are rare, however, and there is no consensus on their pathogenesis and optimal management.

Objective: To characterize cyst growth in patients with symptomatic TCs. Read More

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December 2018

Commentary: Chlorhexidine Showers are Associated With a Reduction in Surgical Site Infection Following Spine Surgery: An Analysis of 4266 Consecutive Surgeries.

Neurosurgery 2018 Dec 11. Epub 2018 Dec 11.

The Spinal Column Biomechanics and Surgical Outcomes Laboratory, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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December 2018

Primary Motor Cortex Transcranial Direct Current Stimulation Modulates Temporal Summation of the Nociceptive Withdrawal Reflex in Healthy Subjects.

Pain Med 2018 Dec 7. Epub 2018 Dec 7.

The Nick Davey Laboratory, Faculty of Medicine, Imperial College London, London, UK.

Objective: Transcranial direct current stimulation (tDCS) over the primary motor cortex (M1) has shown efficacy in a number of chronic pain conditions. Despite attempts to dissect the analgesic mechanisms, it is unknown whether M1 tDCS modulates the central integration of spinal nociception. To test this, we investigated the top-down modulation of spinal excitability using temporal summation (TS) of the nociceptive withdrawal reflex (NWR). Read More

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December 2018

Socioeconomic inequities in health services' utilization following the Health Transformation Plan initiative in Iran.

Health Policy Plan 2018 Dec 7. Epub 2018 Dec 7.

Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Poursina Avenue, Tehran, Iran.

Health equity has become a progressively popular research topic in recent years. Therefore, this study was made to identify the contributions made by socioeconomic determinants in order to quantify their roles to healthcare utilization inequity and to show their status especially after the recent reform in Iran, i.e. Read More

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December 2018

[Incidence of group B streptococcal early-onset sepsis in infants born at Centro Hospitalario Pereira Rossell between 2007-2015].

Rev Chilena Infectol 2018 Aug;35(4):424-430

Departamento de Bacteriología, Centro Hospitalario Pereira Rossell, Montevideo, Uruguay.

Background: Group B Streptococcus (GBS) disease remains the leading cause of early-onset sepsis (EOS) in developed countries despite effective prophylaxis strategies.

Aims: To describe the incidence, clinical features and mortality of GBS EOS in infants born at Centro Hospitalario Pereira Rossell (CHPR) and analyse failure of adherence to prevention strategies.

Methods: Retrospective review of EOS cases between 2007 and 2015 collected from the bacteriology laboratory database. Read More

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Cerebrolysin increases motor recovery and decreases inflammation in a mouse model of autoimmune encephalitis.

Rom J Morphol Embryol 2018 ;59(3):755-762

Department of Research Methodology, University of Medicine and Pharmacy of Craiova, Romania;

Multiple sclerosis (MS) is a complex chronic neurodegenerative disease that involves an abnormal autoimmune response directed against the brain, nerves and spinal cord; it is considered the most frequent cause of neurological disability, because MS-associated inflammatory lesions can affect a wide range of systems to a varying degree and may cause a plethora of neurological comorbidities and symptoms. The symptoms are quite variable from patient to patient and depend on the spatial distribution of the central nervous system (CNS) lesions, but usually involve sensory disturbances, cognitive deficits, unilateral vision loss, bladder dysfunction, ataxia, fatigue, double vision, weakness of the limbs and intestinal disorders. Experimental autoimmune encephalitis (EAE) mouse model reproduces the pathological features of the human disease, and is a widely used model used for studying the pathology and different treatment options in the preclinical stage. Read More

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January 2018

Heme oxygenase-1 inducer and carbon monoxide-releasing molecule enhance the effects of gabapentinoids by modulating glial activation during neuropathic pain in mice.

Pain Rep 2018 Sep-Oct;3(5):e677. Epub 2018 Aug 6.

Department of Anesthesiology and Critical Care Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.

Introduction: Neuropathic pain is one of the most difficult-to-treat symptoms. Although gabapentinoids are classified as first-line drugs, they have only modest efficacy.

Objectives: The aim of this study was to investigate whether treatment with the heme oxygenase-1 (HO-1) inducer cobalt protoporphyrin IX (CoPP) or the carbon monoxide-releasing molecule tricarbonyldichlororuthenium (II) dimer (CORM-2) can enhance the antinociceptive effects produced by gabapentinoids in mice with neuropathic pain. Read More

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Granulocyte-macrophage colony-stimulating factor receptor expression in clinical pain disorder tissues and role in neuronal sensitization.

Pain Rep 2018 Sep-Oct;3(5):e676. Epub 2018 Sep 17.

Peripheral Neuropathy Unit, Centre for Clinical Translation, Department of Medicine, Hammersmith Hospital, Imperial College London, London, United Kingdom.

Introduction: Granulocyte-macrophage colony-stimulating factor receptor (GM-CSFR) is highly expressed in peripheral macrophages and microglia, and is involved in arthritis and cancer pain in animal models. However, there is limited information on GM-CSFR expression in human central nervous system (CNS), peripheral nerves, or dorsal root ganglia (DRG), particularly in chronic pain conditions.

Objectives: Immunohistochemistry was used to quantify GM-CSFR expression levels in human tissues, and functional sensory effects of GM-CSF were studied in cultured DRG neurons. Read More

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September 2018

Testing Pathological Variation of White Matter Tract in Adult Rats after Severe Spinal Cord Injury with MRI.

Biomed Res Int 2018 11;2018:4068156. Epub 2018 Nov 11.

Department of Neurobiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.

The purpose of this study was to assess the pathological variation in white matter tracts in the adult severe thoracic contusion spinal cord injury (SCI) rat models combined with in vivo magnetic resonance imaging (MRI), as well as the effect of spared white matter (WM) quantity on hindlimb motor function recovery. 7.0T MRI was conducted for all experimental animals before SCI and 1, 3, 7, and 14 days after SCI. Read More

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November 2018

Effect of Osteopathic Visceral Manipulation on Pain, Cervical Range of Motion, and Upper Trapezius Muscle Activity in Patients with Chronic Nonspecific Neck Pain and Functional Dyspepsia: A Randomized, Double-Blind, Placebo-Controlled Pilot Study.

Evid Based Complement Alternat Med 2018 11;2018:4929271. Epub 2018 Nov 11.

Postgraduate Program in Rehabilitation Sciences, Physical Therapy Departament, Universidade Nove de Julho, UNINOVE, Brazil.

Previous studies have reported that visceral disturbances can lead to increased musculoskeletal tension and pain in structures innervated from the corresponding spinal level through viscerosomatic reflexes. We designed a pilot randomised placebo-controlled study using placebo visceral manipulation as the control to evaluate the effect of osteopathic visceral manipulation (OVM) of the stomach and liver on pain, cervical mobility, and electromyographic activity of the upper trapezius (UT) muscle in individuals with nonspecific neck pain (NS-NP) and functional dyspepsia. Twenty-eight NS-NP patients were randomly assigned into two groups: treated with OVM (OVMG; = 14) and treated with placebo visceral manipulation (PVMG; = 14). Read More

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November 2018

Effects of spinal mobilization techniques in the management of adolescent idiopathic scoliosis - A meta-analysis.

Int J Health Sci (Qassim) 2018 Nov-Dec;12(6):44-49

Department of physical therapy, Ziauddin College of Rehabilitation Sciences, Ziauddin University, Karachi, Pakistan.

Objectives: The aim of this study is to examine the effectiveness of diverse exercise regimes used in multiple Randomized Control Trials as the only conservative management strategy for increased Cobb angle among Adolescent Idiopathic Scoliosis.

Methods: Database such as Google Scholar, Medline, and BioMed Central was reconnoitered for the purpose of research articles of interest. Studies in which the effects of conservative management of scoliosis on the magnitude of Cobb angle were calculated were scrutinized procedurally, studies fulfilling the inclusion criteria were retrieved and encompassed in the present study. Read More

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December 2018

Draft Genome Sequence of Propionibacterium acnes subsp. elongatum Strain Asn12.

Microbiol Resour Announc 2018 Jul 19;7(2). Epub 2018 Jul 19.

Institute of Biochemistry, Biological Research Centre of the Hungarian Academy of Sciences, Szeged, Hungary.

Propionibacterium acnes, a non-spore-forming anaerobic Gram-positive bacterium, has been linked to a wide range of opportunistic human infections and conditions, most notably acne vulgaris. Here, we present the draft genome sequence of P. acnes subsp. Read More

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Post-traumatic os odontoideum - case presentation and literature review.

Trauma Case Rep 2018 Dec 27;18:46-51. Epub 2018 Nov 27.

Soroka University Medical Center, Department of Spine Surgery, Beer-Sheva, Israel.

Os odontoideum is a rare condition. Nevertheless this condition was described by Giacomini in 1886. It is defined radiologicaly as an oval or round-shaped ossicle of variable size with smooth circumferential cortical margins representing the odontoid process that has no continuity with the body of C2. Read More

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December 2018

Spinal cord injury without radiological abnormality (SCIWORA) manifested as self-limited brown-SEQUARD syndrome.

Trauma Case Rep 2018 Dec 26;18:28-30. Epub 2018 Nov 26.

Gadjah Mada University, Sardjito Hospital, Yogyakarta, Indonesia.

Introduction: Combination between SCIWORA and Brown-Sequard syndrome in a patient is a rare condition. In SCIWORA, there is usually a delay in neurologic deficits which can potentially lead to misdiagnosis. Therefore, the clinician should have a good understanding of the course of the disease to make a good diagnosis and treatment. Read More

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December 2018

Lumbar Schmorl's Nodes and Their Correlation with Spine Configuration and Degeneration.

Biomed Res Int 2018 7;2018:1574020. Epub 2018 Nov 7.

Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.

The aim of this study was to reveal whether demographic aspect, vertebral morphometry, and spine degeneration are associated with lumbar Schmorl's nodes (SNs). A retrospective cross-sectional study was performed using data from the Department of Radiology (Carmel, Medical Center, Israel) for 180 individuals: age range between 40 and 99 years; 90 males and 90 females. All participants had undergone high-resolution CT scans for abdominal diagnostic purposes in the same supine position prior to our study, which enabled the processing of the scans in all planes and allowed a 3D reconstruction of the lower lumbar region. Read More

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November 2018

Clinical Results of Minimally Invasive Spine Stabilization for the Management of Metastatic Spinal Tumors Based on the Epidural Spinal Cord Compression Scale.

Biomed Res Int 2018 8;2018:1258706. Epub 2018 Nov 8.

Department of Orthopaedic Surgery, Nihon University School of Medicine, 30-1 Oyaguchi Kami-cho, Itabashi-ku, Tokyo 173-8610, Japan.

Purpose: Minimally invasive spine stabilization (MISt) using percutaneous pedicle screws plays a significant role in palliative surgery for metastatic spinal tumors. However, few studies have investigated surgical outcomes based on the epidural spinal cord compression scale (ESCCS). The purpose of this study was to examine outcomes of metastatic spinal tumors as evaluated by ESCCS in patients treated by MISt. Read More

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November 2018

Comparison of the Effect of Bupivacaine in Combination with Dexmedetomidine with Bupivacaine Plus Placebo on Neonatal Apgar Score, Bispectral Index, and Sedation Level of Parturient Women.

Anesth Pain Med 2018 Oct 24;8(5):e81947. Epub 2018 Oct 24.

Department of Anesthesiology and Critical Care, Shohada-e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Objectives: In this study, we aimed to compare the effects of bupivacaine alone and in combination with dexmedetomidine on postoperative analgesia, neonatal Apgar score, and bispectral index (BIS), which has been shown to correlate with increased sedation and loss of consciousness in women undergoing cesarean section under spinal anesthesia.

Methods: A total of 152 term parturient women scheduled to have elective cesarean section with American Society of Anesthesiologist (ASA) physical status I or II were allocated randomly into two groups to receive either bupivacaine plus placebo (BV group) or bupivacaine plus dexmedetomidine (BVD group). BIS, sedation scale scores, Apgar scores, and hemodynamic characteristics were recorded and statistically compared between the groups. Read More

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October 2018

Spinal phantom comparability study of Cobb angle measurement of scoliosis using digital radiographic imaging.

J Orthop Translat 2018 Oct 26;15:81-90. Epub 2018 Oct 26.

Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China.

Background: Computed radiography (CR), digital radiography (DR) and biplanar radiography (EOS™ imaging system) are common imaging tools for radiographic evaluation of adolescent idiopathic scoliosis (AIS). The effect of imaging methods in relation to later-on Cobb angle measurements on radiographs is not yet quantified. The study aimed to examine the compatibility between CR, DR and EOS for scoliotic quantification by evaluating the reliability, agreement of different imaging methods, and assessing the prediction performance for EOS measurement from that of CR and DR. Read More

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October 2018

Surgical Intervention vs. Radiation Therapy: The Shifting Paradigm in Treating Metastatic Spinal Disease.

Cureus 2018 Oct 3;10(10):e3406. Epub 2018 Oct 3.

Radiology, Yale School of Medicine/Yale New Haven Health, New Haven, USA.

The spine is one of the most common sites to which metastatic cancer is likely to spread and is one of the leading causes of morbidity and mortality in cancer patients. While no medical treatments have been definitively shown to extend the life expectancy of patients with spinal metastasis, interventional options may be the only viable option in improving outcomes. Currently, two main options exist: surgical resection and radiotherapy, with radiotherapy being the primary treatment modality. Read More

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October 2018

Migrating spinal intradural schwannoma with adjacent disc herniation: A case report and brief literature review.

Surg Neurol Int 2018 5;9:228. Epub 2018 Nov 5.

Department of Neurosurgery, Iran University of Medical Sciences, Tehran, Iran.

Background: Schwannoma is the most common migrating tumor in the intradural space.

Case Description: We present a patient with migrating schwannoma of the cauda which admitted with buttock and thigh pain since 2 years ago. On two preoperative lumbosacral magnetic resonance imaging (MRI), he had a L2/3 disc herniation concomitant with the intradural extra-axial mass at level of the L1/2 disc on the first MRI and then on the second one, his mass was just posterior to the L3 vertebral body, 22 months later. Read More

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November 2018

Lateral position and utility of navigation for posterior fixation of unstable cervical fracture with ankylosing spondylitis.

Surg Neurol Int 2018 2;9:225. Epub 2018 Nov 2.

Grant Medical Center, Department of Neurosurgery, Ohio Health, Columbus, Ohio, USA.

Background: Ankylosing spondylitis (AS) is a seronegative spondyloarthropathy within the spectrum of rheumatologic diseases. The systemic inflammation that characterizes AS leads to bone resorption and reformation. Pathologic remodeling may include kyphosis, osteoporosis, and multi-segment auto-fusion. Read More

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November 2018

Thoracic spine dislocation in Gorham-Stout Syndrome: Case report and literature review.

Surg Neurol Int 2018 1;9:223. Epub 2018 Nov 1.

Spanish Hospital, Mendoza, Argentina.

Background: The Gorham-Stout syndrome (GSS), also known as phantom bone disease, is a rare bone condition of unknown etiology. Involvement of the spine is described in <50 cases in the literature. Here, we report a case of thoracic spine fracture dislocation in a young female who was known to have GSS. Read More

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November 2018

Delayed Diagnosis of Psoriatic Arthritis Mutilans due to Arthritis Prior to Skin Lesion.

Case Rep Rheumatol 2018 4;2018:4216938. Epub 2018 Nov 4.

Department of Orthopedic Surgery, Tokyo Women's Medical University, Tokyo, Japan.

Psoriatic arthritis (PsA) is a type of inflammatory arthritis characterized by cutaneous psoriasis, peripheral joint damage, axial joint damage, and enthesitis and is usually diagnosed after the appearance of psoriatic skin disease. PsA mutilans is relatively rare in Japan. In the present case, the patient was diagnosed with PsA with foot mutilans deformity only. Read More

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November 2018