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Wiad Lek 2021 ;74(4):1045-1049

STATE UNIVERSITY "UZHHOROD NATIONAL UNIVERSITY", UZHHOROD, UKRAINE.

We aim to report a COVID-19-related case of acute myelitis that has not been associated with any other viral infections. A 23-year-old student was admitted to the hospital within a month from the time of loss of smell and taste with features of acute-onset non-compressive myelitis with paresthesia on both sides from the Th9 level. Complex neurological, clinical, laboratory, and neuroimaging examination was performed within 24 hours of admission. Read More

J Orthop Case Rep 2021 ;11(1):72-78

Department of Orthopaedics, Sancheti Institute of Orthopedics and Rehabilitation, Pune, Maharastra, India.

Introduction: We are reporting a rare case of lumbar spinal actinomycosis with superficial discharging sinuses in an elderly female.

Case Report: A 56-year-old female came in outpatient with chief complaints of low back pain radiating to both buttocks, burning sensations to both lower limbs. Magnetic resonance imaging (MRI) re-vealed signal intensity changes suggestive of patchy marrow edema present over the L2 to S1 vertebra. Read More

Neurourol Urodyn 2021 Jun 17. Epub 2021 Jun 17.

Department of Classical Studies, Western University, London, Ontario, Canada.

Objective: To conduct a conjoint analysis experiment to better understand the psychosocial priorities related to bladder management in individuals after spinal cord injury (SCI).

Methods: We developed a conjoint analysis survey that included 11 psychosocial attributes phrased in the context of bladder management (including attributes for urinary infections, and incontinence). We then performed a multi-center prospective cross-sectional study of adults with existing SCI which consisted of a baseline interview, followed by the online conjoint analysis survey (delivered through Sawtooth software). Read More

Ann Rehabil Med 2021 Jun 14. Epub 2021 Jun 14.

Department of Physical Medicine and Rehabilitation, National Rehabilitation Center, Seoul, Korea.

Objective: To assess the incidence of urinary tract infection (UTI) with post-urodynamic study (post-UDS) in patients with spinal cord injury (SCI) and study its relationship with pre-UDS pyuria.

Methods: Patients with SCI who were hospitalized and underwent UDS during a 4-year period were reviewed. Patients with pre-test lower urinary tract symptoms were excluded. Read More

Child Neurol Open 2021 Jan-Dec;8:2329048X211011869. Epub 2021 Jun 1.

Department of Pediatrics, Loyola University Medical Center, Maywood, IL, USA.

Spinal cord abscess is a rare entity, particularly in the pediatric population. Spinal cord abscesses can be located in extradural, subdural and intradural (intramedullary or extramedullary) regions of the cord. Among these locations, intramedullary is extremely uncommon. Read More

J Neurovirol 2021 Jun 8. Epub 2021 Jun 8.

Department of Neurology, Icahn School of Medicine At Mount Sinai, 1468 Madison Avenue, New York, NY, 10029, USA.

Since the onset of the COVID-19 pandemic, there have been rare reports of spinal cord pathology diagnosed as inflammatory myelopathy and suspected spinal cord ischemia after SARS-CoV-2 infection. Herein, we report five cases of clinical myelopathy and myeloradiculopathy in the setting of post-COVID-19 disease, which were all radiographically negative. Unlike prior reports which typically characterized hospitalized patients with severe COVID-19 disease and critical illness, these patients typically had asymptomatic or mild-moderate COVID-19 disease and lacked radiologic evidence of structural spinal cord abnormality. Read More

Neuromodulation 2021 Jun 6. Epub 2021 Jun 6.

Department of Anesthesiology and Critical Care Medicine, Johns Hopkins, Baltimore, MD, USA.

Background And Objectives: Dorsal root ganglion stimulation (DRGS) is a newer form of neuromodulation that targets the dorsal root ganglion. DRGS has superior efficacy in complex regional pain syndrome compared to spinal cord stimulation (SCS) and may have efficacy in other forms of chronic pain. While decades of safety data are available for SCS, there is less available safety information for DRGS. Read More

BMJ Case Rep 2021 Jun 4;14(6). Epub 2021 Jun 4.

Neurology, University Hospitals of Leicester NHS Trust, Leicester, UK.

We report a case of a middle-aged woman, normally fit and well, presenting with acute onset neurological deficit with progression to nadir in <1 hour. Initial MRI spine showed no significant abnormality, although second MRI spine showed abnormal signal in three to four segments with no compressive lesion. CT aortic angiography excluded vascular or ischaemic abnormality. Read More

Medicine (Baltimore) 2021 Jun;100(22):e26141

Department of Anesthesiology and Pain Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Rationale: Transverse myelitis (TM) is a spinal cord inflammatory myelopathy that causes motor/sensory loss and urinary retention below the level of the affected spinal cord. Although a few case reports have described the control of neuropathic pain in patients with TM via spinal cord stimulation, no documented case regarding the control of severe allodynia following TM via intrathecal pump has been described.

Patient Concerns: A 37-year-old woman was referred to a pain clinic for severe intractable pain below the T5 level followed by Sjögren's syndrome-induced TM. Read More

J Med Case Rep 2021 Jun 4;15(1):301. Epub 2021 Jun 4.

Department of Bone Surgery, The Third Affiliated Hospital of Shenzhen University, Shenzhen, 518000, China.

Background: Intercostal neuralgia is most common in patients with herpes zoster, but it might be the initial symptom of serious diseases, such as atraumatic spinal fracture, which may lead to serious consequences if not diagnosed and treated early. Severe intercostal neuralgia is rarely reported as the first symptom of ankylosing spondylitis with atraumatic vertebral fractures.

Case Presentation: A 70-year-old Chinese Han man previously diagnosed with ankylosing spondylitis presented to the hospital with intense intercostal pain without trauma. Read More

BMC Infect Dis 2021 Jun 3;21(1):522. Epub 2021 Jun 3.

National Hospital of Sri Lanka, Colombo 08, Sri Lanka.

Background: Leptospirosis is a zoonotic spirochetal disease caused by Leptospira interrogans. The clinical presentation ranges from an asymptomatic state to a fatal multiorgan dysfunction. Neurological manifestations including aseptic meningitis, spinal cord and peripheral nerve involvement, cranial neuropathies and cerebellar syndrome are well recognized with varying frequencies among patients with this disease. Read More

Int J Mol Sci 2021 May 7;22(9). Epub 2021 May 7.

Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA.

Classical inflammation in response to bacterial, parasitic, or viral infections such as HIV includes local recruitment of neutrophils and macrophages and the production of proinflammatory cytokines and chemokines. Proposed biomarkers of organ integrity in Alcohol Use Disorders (AUD) include elevations in peripheral plasma levels of proinflammatory proteins. In testing this proposal, previous work included a group of human immunodeficiency virus (HIV)-infected individuals as positive controls and identified elevations in the soluble proteins TNFα and IP10; these cytokines were only elevated in AUD individuals seropositive for hepatitis C infection (HCV). Read More

Rev Neurol 2021 06;72(11):397-406

Hospital Universitario de Cruces, Bilbao, España.

Introduction: For more than a decade, following the ECTRIMS Congress, the Post-ECTRIMS Meeting has been held in Spain, where neurologists with expertise in multiple sclerosis (MS) from all over the country meet to review the most relevant latest developments presented at the ECTRIMS congress (on this occasion held together with ACTRIMS).

Aim: This article, published in two parts, summarises the presentations that took place at the Post-ECTRIMS Meeting, held online on 16 and 17 October 2020.

Development: This first part includes the latest results regarding the impact of the environment and lifestyle on risk of MS and its clinical course, and the role of epigenetics and genetic factors on these processes. Read More

J Int Med Res 2021 May;49(5):3000605211016145

Department of Spine Surgery, Lishui Central Hospital, Lishui, China.

Objective: The study aim was to analyse the effect of participatory continuous nursing using the WeChat platform on the complications, family function and compliance of patients with spinal cord injuries.

Methods: This was a randomized controlled trial. Seventy-eight patients with stable disease treated by internal fixation were enrolled in the study from August 2017 to August 2019 and assigned equally to an observation group and a control group. Read More

Spinal Cord Ser Cases 2021 May 25;7(1):40. Epub 2021 May 25.

Orthopedics and Traumatology Unit, Emergency and Urgency Department, A.S.S.T. Grande Ospedale Metropolitano Niguarda, Milan, Italy.

Introduction: Dialysis-related amyloidosis (DRA) can lead to various degenerative conditions but rarely involves the spine with a spinal cord compression.

Case Report: The authors describe a progressive tetraparesis (AIS-B) in a 57-year-old woman with upper cervical dialysis-related amyloidoma. Magnetic resonance imaging (MRI) showed a solid focal mass lesion at the C2-odotoid level with severe spinal cord compression. Read More

Pain Ther 2021 May 25. Epub 2021 May 25.

Nevro Corp, Redwood City, CA, USA.

Background: Chronic pain in head, neck, shoulders and upper limbs is debilitating, and patients usually rely on pain medications or surgery to manage their symptoms. However, given the current opioid epidemic, non-pharmacological interventions that reduce pain, such as spinal cord stimulation (SCS), are needed. The purpose of this study was to review the evidence on paresthesia-free 10 kHz SCS therapy for neck and upper extremity pain. Read More

J Surg Case Rep 2021 May 18;2021(5):rjab163. Epub 2021 May 18.

Instituto Guatemalteco de Seguridad Social, Ortopedia y Traumatología, Guatemala City, Guatemala.

The annual incidence of traumatic spinal cord injury worldwide is 35 patients per million; this incidence is likely to be much higher in Latin America, where stab injuries are a common incidence. Stab injuries to the spine represent a small percentage of these cases; these are rare injuries; its management may differ compared with other penetrating injuries; these injuries are frequently complicated with neurological damage; the most common clinical manifestation is Brown-Sequard syndrome, and the most common segment involved is the thoracic region; stab injuries to the lumbar spine are rarely found in the literature. The management of patients without neurological involvement is controversial due to the risk of neurologic deterioration intraoperatively. Read More

Transl Psychiatry 2021 05 21;11(1):307. Epub 2021 May 21.

Department of Respiratory and Critical Care Medicine, NHC Key Laboratory of Pulmonary Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430022, Wuhan, Hubei, China.

This study aimed to explore the associations between cerebral white matter (WM) alterations, mental health status, and metabolism in recovered COVID-19 patients. We included 28 recovered COVID-19 patients and 27 healthy controls between April 2020 and June 2020. Demographic data, the mental health scores, diffusion-tensor imaging (DTI) data, and plasma metabolomics were collected and compared between the two groups. Read More

Prof Case Manag 2021 Jul-Aug 01;26(4):200-202

Jenny Quigley-Stickney, MSN, BSN, RN, MHA, MA, CCM, ACM-RN, CPHM, is a professional nurse case manager is the Professional Case Manager at Cape Cod Healthcare. Jenny has been active with CMSA/CMSNE for more than 20 years, serving as the President of CMSNE & Chair for both CMSA and CMSNE Public Policy Committees. She is currently serving as one of the Board of Directors for CMSA National. She is active in the New England states, promoting the advancement of the Nurse Licensure Compact, and Telehealth legislation for health care provision. She has a passion for legislative works and believes that legislation helps advance the field of professional case management.

Pediatr Infect Dis J 2021 07;40(7):e266-e267

Department of Pediatrics, Section of Newborn Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

BMJ Case Rep 2021 May 19;14(5). Epub 2021 May 19.

Department of Neurology, Bangur Institute of Neurology, Institute of Postgraduate Medical Education and Research, Kolkata, India.

A patient having clinical features reminiscent of anterior cord syndrome (ACS) was found to have long segment myelitis on MRI. Investigations revealed serum anti-myelin oligodendrocyte glycoprotein (MOG) antibody positivity. He was treated with pulse methylprednisolone followed by immunosuppressant therapy with mycophenolate mofetil, which led to clinical recovery. Read More

BMJ Case Rep 2021 May 19;14(5). Epub 2021 May 19.

Medical Department, Fundacion Cambiando Vidas, Quito, Pichincha, Ecuador.

Transverse myelitis is an inflammatory disease of the central nervous system that disrupts nerve signals' conduction. The illness is characterised by weakness in the lower limbs accompanied by paresthesia and urinary and bowel incontinence. The most disabling sequel is the onset of chronic neuropathic pain, which can severely limit the patient's independence and negatively affect her quality of life. Read More

BMC Pediatr 2021 05 19;21(1):242. Epub 2021 May 19.

Department of Anesthesiology, Rutgers New Jersey Medical School, Newark, NJ, USA.

Background: Spinal arteriovenous malformations in children are extremely rare and pose great risk for intraoperative hemorrhage. Congenital syphilis sometimes presents with vascular symptoms, however, there is little published on patients with a history of congenital syphilis presenting with spinal arteriovenous malformations.

Case Presentation: A 15-month-old female with a history of congenital syphilis presented with urinary retention, fever, and subacute onset of paraplegia. Read More

J Clin Neurosci 2021 Jun 4;88:128-134. Epub 2021 Apr 4.

Department of Neurosurgery, Stanford University School of Medicine, 300 Pasteur Drive, Palo Alto, CA 94305, USA; Department of Neurosurgery, Santa Clara Valley Medical Center, 751 S Bascom Ave, San Jose, CA 95128, USA. Electronic address:

Early COVID-19-targeted legislations reduced public activity and elective surgery such that local neurosurgical care greatly focused on emergent needs. This study examines neurosurgical trauma patients' dispositions through two neighboring trauma centers to inform resource allocation. We conducted a retrospective review of the trauma registries for two Level 1 Trauma Centers in Santa Clara County, one academic and one community center, between February 1st and April 15th, 2018-2020. Read More

J Spinal Cord Med 2021 May 13:1-4. Epub 2021 May 13.

College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, USA.

Context: Pyocystis is an infection of the epithelium of the bladder and a frequent complication of anuria. Patients with spinal cord injury (SCI) at the sixth thoracic vertebra (T6) or higher are at a greater risk for autonomic dysreflexia (AD), which can be induced by infections such as pyocystis. Cases of pyocystis treatment with aminoglycoside instillations have been reported in the literature. Read More

Front Immunol 2021 26;12:653786. Epub 2021 Apr 26.

Neurosurgery Service, Complejo Hospitalario Metropolitano, CSS, Panama City, Panama.

Introduction: Although acute transverse myelitis (ATM) is a rare neurological condition (1.34-4.6 cases per million/year) COVID-19-associated ATM cases have occurred during the pandemic. Read More

J Med Case Rep 2021 May 12;15(1):233. Epub 2021 May 12.

Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.

Background: Brown-Séquard syndrome often occurs in spinal cord injury, and few myelitis patients present with Brown-Séquard syndrome.

Case Presentation: A 33-year-old Han man was admitted with neck pain plus numbness in the right limbs for 2 days and weakness in the left limbs for 1 day. Examination was significant for left limbs with grade 4 muscle power, positive left Babinski sign, diminished vibration sensation in the left limbs and decreased pain below the right clavicle dermatome. Read More

Spinal Cord 2021 May 7. Epub 2021 May 7.

Department of Neuro-Urology, Balgrist University Hospital, University of Zürich, Zürich, Switzerland.

Bacterial infections are the leading cause of death in people with a spinal cord injury (SCI). Bacteriophages (phages) are viruses that solely infect and kill bacteria. The idea of using phages to treat bacterial infections, i. Read More

J Spinal Cord Med 2021 May 6:1-9. Epub 2021 May 6.

Rural Clinical School in Family Medicine, University of New South Wales, Sydney, Australia.

Objective: The purpose of this study was to find the most and least commonly prescribed medications for treating secondary health complications associated with spinal cord injury (SCI); and determine overall polypharmacy rates and risk factors associated with it.

Design: Observational design, cross-sectional analysis.

Setting: Community; Canada. Read More

Rev Soc Bras Med Trop 2021 28;54:e0115 2021. Epub 2021 Apr 28.

Universidade Estadual de Campinas, Faculdade de Ciências Médicas, Departamento de Radiologia, Campinas, SP, Brasil.