2,105 results match your criteria Spinal Cord Infarction


[Lumbosacral radiculoplexus neuropathy with a small intramedullary lesion in posterior spinal cord: a case report].

Authors:
Motomi Arai

Rinsho Shinkeigaku 2018 Nov 29. Epub 2018 Nov 29.

Department of Neurology, Seirei Mikatahara General Hospital.

We present the unique case of a patient with lumbosacral radiculoplexus neuropathy (LRPN) and a small intramedullary lesion, probably an infarction, in the spinal cord. A previously healthy 58-year-old female developed acute severe pain involving the entire right lower limb, followed by weakness of the right lower limb a few hours later. The patient could not walk and was referred to our clinic. Read More

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http://dx.doi.org/10.5692/clinicalneurol.cn-001213DOI Listing
November 2018
1 Read

[Surgical Experience of Total Arch Replacement Using Frozen Elephant Trunk, for Type B Acute Aortic Dissection].

Kyobu Geka 2018 Nov;71(12):989-994

Department of Cardiovascular Surgery, Yokohama Rosai Hospital, Yokohama, Japan.

Recently, advanced technique and device of thoracic endovascular aortic repair (TEVAR) enabled surgical intervention for type B acute aortic dissection (BAD). However, BAD have often serious complications;cerebral infarction, spinal cord infarction, multi-organ ischemia or necrosis, and retrograde type A acute aortic dissection. TEVAR is performed for complicated BAD for the aim of life saving in such a failure case of conservative treatment. Read More

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November 2018
5 Reads

Alterations in the spinal cord and ventral root after cerebral infarction in non-human primates.

Restor Neurol Neurosci 2018 ;36(6):729-740

Department of Neurology and Stroke Center, National Key Clinical Department and Key Discipline of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

Backgrounds: Cerebral infarction does not only cause focal injury in the ischemic site, but also secondary non-ischemic damage at the remote areas of nervous system associated with the primary focus.

Objective: This study investigated the changes in the spinal cord and ventral root after middle cerebral artery occlusion (MCAO) in cynomolgus monkeys (Macaca fascicularis).

Methods: Adult male cynonolgus monkeys (4-5 years, 5. Read More

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http://www.medra.org/servlet/aliasResolver?alias=iospress&am
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http://dx.doi.org/10.3233/RNN-180854DOI Listing
January 2018
18 Reads

Paraplegia After Basketball Play: A Case of Spinal Cord Infarction Secondary to Fibrocartilaginous Embolization.

Pediatr Emerg Care 2018 Nov 5. Epub 2018 Nov 5.

Departments of Medical Education and Pediatrics, Section of General Pediatrics, West Virginia University School of Medicine, Morgantown, WV.

Pediatric emergency medicine providers must be astute at generating the differential diagnosis and performing the appropriate evaluation to promptly determine the underlying cause of new onset paraplegia. Spinal cord infarction (SCI) is a potential etiology of paraplegia in children, and fibrocartilaginous embolization is a rare underlying cause of SCI. We present an illustrative case of SCI secondary to fibrocartilaginous embolization in an otherwise healthy adolescent who developed symptoms of spinal cord dysfunction after basketball play. Read More

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http://dx.doi.org/10.1097/PEC.0000000000001666DOI Listing
November 2018

Delayed-Onset Paraplegia Due to Spinal Cord Infarction After Repeated Tumor Excision Surgeries of the Thoracic Spine.

Orthopedics 2018 Oct 26:1-4. Epub 2018 Oct 26.

Tumor excision surgeries of the spine present a distinct challenge regarding the maintenance of spinal cord blood supply because they often require preoperative embolization of segmental arteries, ligation of the corresponding nerve roots, and circumferential exposure of the dural sac. The authors present a case of delayed-onset spinal cord infarction after repeated tumor excision surgeries of the thoracic spine. A 49-year-old man had undergone a left nephrectomy for renal cell carcinoma, 2 pulmonary metastasectomies, and excision of a left sixth rib metastasis before referral to the authors' institution. Read More

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https://www.healio.com/doiresolver?doi=10.3928/01477447-2018
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http://dx.doi.org/10.3928/01477447-20181023-07DOI Listing
October 2018
4 Reads

Anterior spinal cord syndrome as a rare complication of acute bacterial meningitis in an adult.

BMJ Case Rep 2018 Oct 24;2018. Epub 2018 Oct 24.

Department of Medicine (Neurology), School of Medical Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.

Acute bacterial meningitis is not an uncommon central nervous system infection. In severe cases, it can be associated with various neurological or systemic complications. However, acute spinal cord dysfunction rarely occurs. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22608
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http://dx.doi.org/10.1136/bcr-2018-226082DOI Listing
October 2018
5 Reads

Spinal Cord Infarction Because of Spontaneous Vertebral Artery Dissection.

Stroke 2018 Nov;49(11):e314-e317

From the Department of Neurology, Warren Alpert Medical School of Brown University, Providence, RI (M.M., A.B., I.A., L.K., S.Y.).

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http://dx.doi.org/10.1161/STROKEAHA.118.022333DOI Listing
November 2018
2 Reads

Sudden Collapse due to Medullary and Cervical Cord Infarction-An Unusual Presentation of Hepatocellular Carcinoma.

J Forensic Sci 2018 Oct 23. Epub 2018 Oct 23.

Department of Anatomical Pathology, Singapore General Hospital, 20 College Road, Singapore, 169856, Singapore.

Hepatocellular carcinoma (HCC) is a common cancer worldwide with a great potential for metastatic spread. Hepatocellular carcinoma often arises in people with underlying viral hepatitides or liver cirrhosis and may present in various ways including abdominal pain, liver mass, and signs of hepatocellular decompensation. Many tumors may have metastasized to other organs such as the lungs, lymph nodes, bone, and adrenal glands at the time of diagnosis. Read More

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http://doi.wiley.com/10.1111/1556-4029.13929
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http://dx.doi.org/10.1111/1556-4029.13929DOI Listing
October 2018
5 Reads

Spinal cord infarction with ipsilateral segmental neuropathic pain and flaccid paralysis. A functional role for human afferent ventral root small sensory fibres.

J Neurol Sci 2018 Dec 1;395:84-87. Epub 2018 Oct 1.

Faculad de Medicina, Universidad de Chile, Chile; Imperial College, London, UK.

This paper illustrates the cases of two patients with an acute onset of right brachial neuropathic pain, flaccid paralysis and contralateral thermal and thermal pain hypoesthesia, without posterior column impairment nor pyramidal signs below the segmental lesion. MRI showed right sided spinal cord infarction, in the anterior spinal artery territory between C1 and C5 in one patient and between C3 and C7 in the other. Contact Heat Evoked Potentials and Quantitative Thermal Sensory testing are consistent with contralateral, but not ipsilateral, spinothalamic tract involvement. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0022510X183039
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http://dx.doi.org/10.1016/j.jns.2018.09.037DOI Listing
December 2018
3 Reads

Cerebrospinal fluid drainage and blood pressure elevation to treat acute spinal cord infarct.

Surg Neurol Int 2018 21;9:195. Epub 2018 Sep 21.

Cerebrovascular Center, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA.

Background: Current management of acute spinal cord infarction (SCI) is limited. Lumbar cerebrospinal fluid drainage (CSFD) with blood pressure augmentation is utilized in the thoracic/thoracoabdominal aortic repair and thoracic endovascular aortic repair (TEVAR) populations to increase spinal perfusion pressure.

Case Description: We identified 3 patients who sustained acute SCI and underwent CSFD and maintenance of elevated mean arterial pressure (MAP) within 24 hours of injury. Read More

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http://www.surgicalneurologyint.com/text.asp?2018/9/1/195/24
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http://dx.doi.org/10.4103/sni.sni_2_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169349PMC
September 2018
2 Reads

Characteristics of Spontaneous Spinal Cord Infarction and Proposed Diagnostic Criteria.

JAMA Neurol 2018 Sep 24. Epub 2018 Sep 24.

Department of Neurology, Mayo Clinic, Rochester, Minnesota.

Importance: Spinal cord infarction (SCI) is often disabling, and the diagnosis can be challenging without an inciting event (eg, aortic surgery). Patients with a spontaneous SCI are often misdiagnosed as having transverse myelitis. Diagnostic criteria for SCI are lacking, hindering clinical care and research. Read More

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http://archneur.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamaneurol.2018.2734DOI Listing
September 2018
7 Reads

Microsurgical Management of a Spinal Dural Arteriovenous Fistula With Shared Blood Supply to the Artery of Adamkiewicz: 3-Dimensional Operative Video.

Oper Neurosurg (Hagerstown) 2018 Sep 24. Epub 2018 Sep 24.

Department of Neurosurgery, Emory University School of Medicine, Atlanta, Georgia.

The presented case is of a 65-yr-old gentleman referred for thoracic myelopathy. He developed bilateral, nondermatomal foot dysesthesia 14 mo prior to presentation, which progressed to numbness below the L3 level. He reported progressive gait instability, bilateral lower extremity weakness, and required a cane for ambulation. Read More

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http://dx.doi.org/10.1093/ons/opy293DOI Listing
September 2018
5 Reads

[Effect of spinal cord stimulation on myocardial ischemia/infarction].

Zhejiang Da Xue Xue Bao Yi Xue Ban 2018 May;47(2):201-206

Department of Cardiology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.

Fatal arrhythmias, heart failure, and sudden cardiac death after myocardial ischemia/infarction are serious threats to human health. In recent years, studies have shown that spinal cord stimulation (SCS) can balance autonomic activity, inhibit myocardial structural remodeling, improve blood flow to ischemic myocardium, effectively reduce the incidence of arrhythmia, heart failure and sudden cardiac death after myocardial ischemia/infarction, but its specific mechanism has not yet been fully elucidated. The effect of SCS on cardiac function may be achieved by inhibiting neural remodeling, or by ameliorating structural remodeling and electrical remodeling. Read More

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Towards rationally designed biomanufacturing of therapeutic extracellular vesicles: impact of the bioproduction microenvironment.

Biotechnol Adv 2018 Dec 12;36(8):2051-2059. Epub 2018 Sep 12.

Fischell Department of Bioengineering, University of Maryland, 3102 A. James Clark Hall, College Park, MD 20742, United States; Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, Baltimore, MD 21201, United States; Program in Molecular and Cell Biology, University of Maryland, College Park, MD 20742, United States. Electronic address:

Extracellular vesicles (EVs), including exosomes, microvesicles, and others, have emerged as potential therapeutics for a variety of applications. Pre-clinical reports of EV efficacy in treatment of non-healing wounds, myocardial infarction, osteoarthritis, traumatic brain injury, spinal cord injury, and many other injuries and diseases demonstrate the versatility of this nascent therapeutic modality. EVs have also been demonstrated to be effective in humans, and clinical trials are underway to further explore their potential. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07349750183015
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http://dx.doi.org/10.1016/j.biotechadv.2018.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250573PMC
December 2018
23 Reads

Methods for Assessing Serpins as Neuroprotective Therapeutics.

Authors:
Jacek M Kwiecien

Methods Mol Biol 2018 ;1826:223-235

Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada.

As the systematic work on the pathogenesis of the white matter injury in the spinal cord models progresses, it becomes obvious that a severe and extraordinarily protracted, destructive inflammation follows the initial injury. Appropriate anti-inflammatory therapies of sufficient duration should not only inhibit but also lead to the elimination of this destructive inflammation, thus resulting in neuroprotection of the spinal cord tissue and a greater preservation of the neurologic function. While dexamethasone, a powerful, anti-inflammatory steroid analog administered continuously by subdural infusion for 7 days inhibited severe macrophage infiltration in the cavity of injury, the dose used was remarkably toxic. Read More

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http://dx.doi.org/10.1007/978-1-4939-8645-3_15DOI Listing
January 2018
1 Read

Delayed cerebellar infarction after a slight electric injury.

Am J Emerg Med 2018 Dec 27;36(12):2337.e3-2337.e5. Epub 2018 Aug 27.

ICU, Ningbo Medical Center Lihuili Eastern Hospital, No 1111, Jiangnan Rd, Ningbo 315100, China. Electronic address:

Electrical injury causes direct damage to nerves. It may manifest as peripheral nerve injury, spinal cord damage, cerebellar ataxia, hypoxic encephalopathy, or intracerebral hemorrhage. Various factors determine the severity of electric injury, including type of current, amperage, voltage, tissue resistance, pathway of the current, and duration of contact with the body. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07356757183071
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http://dx.doi.org/10.1016/j.ajem.2018.08.064DOI Listing
December 2018
7 Reads

Deep chronic microvascular white matter ischemic change as an independent predictor of acute brain infarction after thoracic aortic replacement.

J Card Surg 2018 Sep 2;33(9):552-560. Epub 2018 Sep 2.

Department of Neuroradiology, Imaging Institute, Cleveland Clinic, Cleveland, Ohio.

Background: Postoperative brain injury is a cause of mortality and morbidity in patients who undergo thoracic aortic replacement. Chronic microvascular white matter ischemic change (WMIC) has been shown to be associated with acute brain infarction in the general population. WMIC has also been shown to be an independent predictor of non-focal neurocognitive changes, generalized seizures, and temporary neurologic dysfunction in patients who undergo thoracic aortic replacement. Read More

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http://doi.wiley.com/10.1111/jocs.13786
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http://dx.doi.org/10.1111/jocs.13786DOI Listing
September 2018
6 Reads
0.890 Impact Factor

Spinal cord infarction during physical exertion due to polycythemia vera and aortoiliac occlusive disease: A case report.

Medicine (Baltimore) 2018 Aug;97(35):e12181

Department of Physical Medicine and Rehabilitation, National Cheng Kung University Hospital.

Rationale: Spinal cord infarction is rarely caused by hypercoagulable states. Polycythemia vera (PV) is a myeloproliferative neoplasm that can contribute to thrombotic events due to increased blood viscosity. We report a case of spinal cord infarction due to extensive aortic thrombosis caused by PV. Read More

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http://dx.doi.org/10.1097/MD.0000000000012181DOI Listing
August 2018
2 Reads

Microsurgical Excision of T12-L1 Pial Arteriovenous Malformation: 3-Dimensional Operative Video.

Oper Neurosurg (Hagerstown) 2018 Aug 30. Epub 2018 Aug 30.

Department of Neurosurgery, University of Washington, Seattle, Washington.

This 29-yr-old man presented with progressive paraparesis, sensory loss, allodynia, bowel, and bladder dysfunction for 9 mo, acutely exacerbated in the preceding 24 h. Magnetic resonance imaging scan showed multiple dilated vessels involving the thoracic cord. Spinal angiogram revealed a T12-L1 pial arteriovenous malformation (AVM)/arteriovenous fistula on the left side. Read More

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https://academic.oup.com/ons/advance-article/doi/10.1093/ons
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http://dx.doi.org/10.1093/ons/opy243DOI Listing
August 2018
10 Reads

Towards BCI-actuated smart wheelchair system.

Biomed Eng Online 2018 Aug 20;17(1):111. Epub 2018 Aug 20.

College of Artificial Intelligence, National University of Defense Technology, Deya Road, Changsha, 410000, People's Republic of China.

Background: Electroencephalogram-based brain-computer interfaces (BCIs) represent novel human machine interactive technology that allows people to communicate and interact with the external world without relying on their peripheral muscles and nervous system. Among BCI systems, brain-actuated wheelchairs are promising systems for the rehabilitation of severely motor disabled individuals who are unable to control a wheelchair by conventional interfaces. Previous related studies realized the easy use of brain-actuated wheelchairs that enable people to navigate the wheelchair through simple commands; however, these systems rely on offline calibration of the environment. Read More

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http://dx.doi.org/10.1186/s12938-018-0545-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102906PMC
August 2018
10 Reads

Sympathetic nervous remodeling is induced in the intermediolateral nucleus after myocardial infarction - Role of BDNF-TrkB axis.

Neurosci Lett 2018 Oct 16;685:114-123. Epub 2018 Aug 16.

Department of Cardiovascular Medicine, Fukushima Medical University, Fukushima, Japan.

Several studies have shown that neural remodeling in stellate ganglia (SG) is induced by myocardial infarction (MI). It remains unclear whether neural remodeling after MI is limited in SG within the sympathetic nervous system (SNS). MI was induced in a rat model by ligation of the left anterior descending artery. Read More

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http://dx.doi.org/10.1016/j.neulet.2018.08.004DOI Listing
October 2018

Correlation of Brain Perfusion with White Matter Hyperintensity, Brain Atrophy, and Cognition in Patients with Posterior Cerebral Artery Stenosis and Subjective Cognitive Decline.

Med Sci Monit 2018 Aug 17;24:5729-5738. Epub 2018 Aug 17.

Department of Neurology, Tongji Hospital, Tongji University School of Medicine, Tongji University, Shanghai, China (mainland).

BACKGROUND This study aimed to investigate the correlation of brain perfusion with white matter hyperintensity (WMH), brain atrophy, and cognition in patients with moderate to severe posterior cerebral artery stenosis (PCAS). MATERIAL AND METHODS 65 patients with memory decline as the main complaint and no history of brain infarction were recruited from the Department of Neurology of Tongji Hospital. Patients with moderate to severe PCAS were included in case group, and subjects with normal intracranial blood vessels served as controls. Read More

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http://dx.doi.org/10.12659/MSM.909188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109365PMC
August 2018
9 Reads

Spinal Cord Infarction: Clinical and Radiological Features.

J Stroke Cerebrovasc Dis 2018 Oct 6;27(10):2810-2821. Epub 2018 Aug 6.

Department of Neurology, National Institute of Mental Health and Neurosciences, Bangalore 560029, India. Electronic address:

Introduction: Spinal cord infarction is an uncommon disease varying in its clinical presentation. This study describes the clinical and radiological presentation of spinal cord infarcts in 17 consecutive patients.

Material And Methods: Clinical and MR imaging data of 17 patients were reviewed. Read More

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2018.06.008DOI Listing
October 2018
1 Read

Unilateral Upper Cervical Posterior Spinal Cord Infarction after a Neuroendovascular Intervention: A Case Report.

Case Rep Neurol Med 2018 5;2018:5070712. Epub 2018 Jul 5.

Department of Neurology, University of Mississippi Medical Center, Jackson, USA.

Context: We describe a case of unilateral posterior upper cervical spinal cord infarction and propose a pathophysiologic mechanism causing this lesion after vertebral artery endovascular intervention.

Findings: A 70-year-old male presented with subacute onset of left hemibody sensory changes and gait instability following a left vertebral angioplasty procedure. MRI cervical spine revealed upper posterior cervical spinal cord infarction (PSCI). Read More

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http://dx.doi.org/10.1155/2018/5070712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057308PMC

Experience with thoracic endovascular aortic repair applied in treating Stanford type B aortic dissection: An analysis of 98 cases.

Adv Clin Exp Med 2018 Sep;27(9):1259-1262

Department of Vascular Surgery, Chengde Medical University Affiliated Hospital, China.

Background: Thoracic endovascular aortic repair (TEVAR) has been frequently applied in Stanford type B aortic dissection since thoracic aortic diseases were first treated with artificial vessels.

Objectives: The aim of this study was to analyze the clinical value of TEVAR applied in treating Stanford type B aortic dissection.

Material And Methods: Between January 2007 and April 2014, 167 consecutive Stanford type B aortic dissection patients were treated with TEVAR and retrospectively analyzed. Read More

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http://dx.doi.org/10.17219/acem/70453DOI Listing
September 2018
2 Reads

Impact of Perioperative Neurologic Deficits on Clinical Outcomes After Posterior Cervical Fusion.

World Neurosurg 2018 Nov 24;119:e250-e261. Epub 2018 Jul 24.

Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA. Electronic address:

Background: In the United States, the number of posterior cervical fusions has increased substantially. Perioperative neurologic complications associated with this procedure, such as spinal cord and peripheral nerve injuries, can have significant effects on patient health. We examined the impact of perioperative neurologic deficits on mortality in patients undergoing posterior cervical fusion. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.07.126DOI Listing
November 2018
6 Reads

Spinal Cord Infarction with Aortic Dissection.

Case Rep Orthop 2018 28;2018:7042829. Epub 2018 Jun 28.

Department of Orthopedic Surgery, Saiseikai Kawaguchi General Hospital, 5-11-5 Nishikawaguchi, Kawaguchi, Saitama 332-8558, Japan.

Spinal cord infarction is an uncommon but devastating disorder caused by various conditions. Aortic dissection is a possible etiological factor and is usually associated with severe chest or back pain. We encountered two cases of spinal cord infarction associated with aortic dissection that presented without typical severe pain, and each case resulted in a different clinical course. Read More

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http://dx.doi.org/10.1155/2018/7042829DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046175PMC

Azithromycin therapy reduces cardiac inflammation and mitigates adverse cardiac remodeling after myocardial infarction: Potential therapeutic targets in ischemic heart disease.

PLoS One 2018 12;13(7):e0200474. Epub 2018 Jul 12.

Gill Heart Institute and Division of Cardiovascular Medicine, University of Kentucky, Lexington, KY, United States of America.

Introduction: Acute myocardial infarction (MI) is a primary cause of worldwide morbidity and mortality. Macrophages are fundamental components of post-MI inflammation. Pro-inflammatory macrophages can lead to adverse cardiac remodeling and heart failure while anti-inflammatory/reparative macrophages enhance tissue healing. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0200474PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042749PMC
July 2018
5 Reads
3.230 Impact Factor

Cervical Cord Infarction Caused by Dissection of the Intracranial Segment of the Vertebral Artery.

Intern Med 2018 Nov 6;57(22):3321-3324. Epub 2018 Jul 6.

Department of Neurology, Otsu Red-Cross Hospital, Japan.

Cervical cord infarction is uncommon but has been increasingly reported as a complication of vertebral artery dissection (VAD). A 54-year-old woman presented with neck pain and neurological deficit following sudden neck movement. Radiological findings suggested cervical cord infarction in the anterior spinal artery territory at the C5-C6 vertebral level and dissection of the intracranial segment of the right vertebral artery. Read More

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http://dx.doi.org/10.2169/internalmedicine.0608-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287998PMC
November 2018
9 Reads

Symptomatic Lacunar Infarct Accompanied with Posterior Reversible Encephalopathy Syndrome: A Case Report.

Tokai J Exp Clin Med 2018 Jul 20;43(2):64-67. Epub 2018 Jul 20.

Division of Neurology, Department of Internal Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan.

We present a 48-year-old man with a history of hypertension, who suddenly noticed dysarthria and right hemiparesis. Diffusion-weighted MRI at 1 day after the onset showed a small high-intensity region in the left corona radiata, indicating the acute phase of lacunar infarction. Fluid attenuation inversion recovery images showed extensive hyperintense lesions predominantly in the white matter of the fronto-temporoparietal lobes and pons, indicating posterior reversible encephalopathy syndrome (PRES). Read More

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July 2018
2 Reads

A difficult situation - balancing critical anticoagulation versus the risk of permanent neurologic deficit: a case report.

J Med Case Rep 2018 Jun 22;12(1):180. Epub 2018 Jun 22.

University of Florida College of Medicine, 1600 SW Archer Rd, Gainesville, FL, 32610, USA.

Background: Anticoagulation is the mainstay of treatment for pulmonary embolism. However, if bleeding unfortunately occurs, the risks and benefits of anticoagulation present a challenge. Management of one hemorrhagic complication, retroperitoneal hematoma, is rare, difficult, and controversial. Read More

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http://dx.doi.org/10.1186/s13256-018-1688-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013867PMC
June 2018
6 Reads

Atypical spinal cord infarction: A case report.

Medicine (Baltimore) 2018 Jun;97(23):e11058

Introduction: The abrupt onset of sensorimotor deficits is a neurologic emergency that requires immediate management. Acute spontaneous spinal cord infarction (SCI) is rare, but can cause the sudden onset of quadriplegia or quadriparesis. Magnetic resonance imaging (MRI) is an essential imaging modality to diagnose SCI. Read More

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http://dx.doi.org/10.1097/MD.0000000000011058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999478PMC
June 2018
2 Reads

Dead Legs: A Case of Bilateral Leg Paralysis.

Clin Pract Cases Emerg Med 2017 Nov 3;1(4):315-318. Epub 2017 Oct 3.

Desert Regional Medical Center, Department of Emergency Medicine, Palm Springs, California.

Aortoiliac occlusive disease (AOD) is a rare presentation of thrombosis of the abdominal aorta. Also known as Leriche syndrome, its classic description entails claudication of the buttocks, thighs, and calves, absent femoral pulses, and impotence. AOD risk factors include smoking, hypertension, hyperlipidemia, diabetes, chronic renal insufficiency, and hypercoagulopathy. Read More

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http://dx.doi.org/10.5811/cpcem.2017.5.34091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965203PMC
November 2017
2 Reads

Fibrocartilaginous embolic myelopathy: demographics, clinical presentation, and functional outcomes.

Spinal Cord 2018 Dec 25;56(12):1144-1150. Epub 2018 May 25.

Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA.

Study Design: Retrospective cohort study.

Objectives: To describe the demographics, clinical presentation, and functional outcomes of fibrocartilaginous embolic myelopathy (FCEM).

Setting: Academic inpatient rehabilitation unit in the midwestern United States. Read More

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http://dx.doi.org/10.1038/s41393-018-0159-yDOI Listing
December 2018

Rapid Automated Quantification of Cerebral Leukoaraiosis on CT Images: A Multicenter Validation Study.

Radiology 2018 08 15;288(2):573-581. Epub 2018 May 15.

From the Biomedical Imaging Analysis Group, Computer Science (L.C., D.R.), and Division of Brain Sciences (L.C., A.L.C.J., A.G., J.G., N.M., A.D., B.A., A.M., P.B.), Imperial College London, Charing Cross Hospital, Fulham Palace Rd, 10L21, London W6 8RF, England; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, Scotland (G.M., J.W.); and Department of Radiology, Northwick Park Hospital, London North West Healthcare NHS Trust, London, England (R.P., D.C.).

Purpose To validate a random forest method for segmenting cerebral white matter lesions (WMLs) on computed tomographic (CT) images in a multicenter cohort of patients with acute ischemic stroke, by comparison with fluid-attenuated recovery (FLAIR) magnetic resonance (MR) images and expert consensus. Materials and Methods A retrospective sample of 1082 acute ischemic stroke cases was obtained that was composed of unselected patients who were treated with thrombolysis or who were undergoing contemporaneous MR imaging and CT, and a subset of International Stroke Thrombolysis-3 trial participants. Automated delineations of WML on images were validated relative to experts' manual tracings on CT images, and co-registered FLAIR MR imaging, and ratings were performed by using two conventional ordinal scales. Read More

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http://pubs.rsna.org/doi/10.1148/radiol.2018171567
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http://dx.doi.org/10.1148/radiol.2018171567DOI Listing
August 2018
5 Reads

Patients receiving chiropractic care in a neurorehabilitation hospital: a descriptive study.

J Multidiscip Healthc 2018 3;11:223-231. Epub 2018 May 3.

Palmer Center for Chiropractic Research, Palmer College of Chiropractic, Davenport, IA, USA.

Objectives: Individuals rehabilitating from complex neurological injury require a multidisciplinary approach, which typically does not include chiropractic care. This study describes inpatients receiving multidisciplinary rehabilitation including chiropractic care for brain injury, spinal cord injury (SCI), stroke, and other complex neurological conditions.

Design: Chiropractic services were integrated into Crotched Mountain Specialty Hospital (CMSH) through this project. Read More

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http://dx.doi.org/10.2147/JMDH.S159618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937508PMC
May 2018
5 Reads

Angiocentric lymph proliferative disorder (lymphomatoid granulomatosis) in a person with newly-diagnosed HIV infection: a case report.

BMC Infect Dis 2018 05 8;18(1):210. Epub 2018 May 8.

Division of Infectious Diseases and Chronic Viral Illness Service, McGill University Health Centre, Royal Victoria Hospital, Glen Site, 1001 boulevard Decarie, Montreal, QC, H4A 3J1, Canada.

Background: Angiocentric lymph proliferative disorder (ALPD) is a granulomatous lymphoproliferative condition associated with various primary and secondary immunodeficiency states. ALPD is so rare that its prevalence has not been established. Typically affecting middle-aged adults, this condition is often found in the context of Epstein Bar Virus infection and consists of angiocentric and angioinvasive pulmonary infiltrates. Read More

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http://dx.doi.org/10.1186/s12879-018-3128-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941628PMC
May 2018
2 Reads

Celiac crisis, a rare and profound presentation of celiac disease: a case report.

BMC Gastroenterol 2018 May 2;18(1):59. Epub 2018 May 2.

Diagnostic, Emergency and Medical Services, Gold Coast Hospital and Health Service, Gold Coast University Hospital, 1 Hospital Blvd, Southport, Gold Coast, Queensland, 4215, Australia.

Background: Celiac crisis is a life-threatening manifestation of celiac disease and is rare in adults, with only a handful of cases documented worldwide and mostly in children.

Case Presentation: A profoundly emaciated 43-year-old female presented with profuse diarrhoea, shortness of breath, left leg swelling with ulceration and immobility (Body Mass Index (BMI) = 14.7 kg/m). Read More

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http://dx.doi.org/10.1186/s12876-018-0784-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932891PMC
May 2018
1 Read

Editor's Choice - Open Thoracic and Thoraco-abdominal Aortic Repair After Prior Endovascular Therapy.

Eur J Vasc Endovasc Surg 2018 Jul 26;56(1):57-67. Epub 2018 Apr 26.

European Vascular Centre Aachen-Maastricht, Department of Vascular Surgery, RWTH University Hospital Aachen, Germany; European Vascular Centre Aachen-Maastricht, Department of Vascular Surgery, AZM University Hospital Maastricht, The Netherlands. Electronic address:

Objective: The aim was to present current results of open thoracic and thoraco-abdominal aortic repair as secondary procedure after prior endovascular therapy.

Methods: This was a retrospective cross border single centre study. From 2006 to July 2017 45 open thoracic aortic (TAA) or thoraco-abdominal aortic aneurysm (TAAA) operations were performed on 44 patients (median age 58 [15-80] years) as secondary surgery after previous endovascular therapy comprising TEVAR (n = 38; 86%), EVAR (n = 3; 7%), fenestrated EVAR (n = 1; 2%) and TEVAR plus EVAR (n = 1; 2%). Read More

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http://dx.doi.org/10.1016/j.ejvs.2018.03.015DOI Listing
July 2018
5 Reads

Granulocyte-colony stimulating factor administration for neurological improvement in patients with postrehabilitation chronic incomplete traumatic spinal cord injuries: a double-blind randomized controlled clinical trial.

J Neurosurg Spine 2018 Jul 27;29(1):97-107. Epub 2018 Apr 27.

Department of Neurosurgery, Imam Khomeini Hospital, Tehran University of Medical Sciences.

OBJECTIVE Granulocyte-colony stimulating factor (G-CSF) is a major growth factor for activation and differentiation of granulocyte colonies in the bone marrow. This cytokine has been widely and safely employed in different conditions over many years. The purpose of this study was to investigate the efficacy of G-CSF administration for traumatic spinal cord injury (TSCI). Read More

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http://dx.doi.org/10.3171/2017.11.SPINE17769DOI Listing
July 2018
8 Reads

Brain and spinal cord injury repair by implantation of human neural progenitor cells seeded onto polymer scaffolds.

Exp Mol Med 2018 04 20;50(4):39. Epub 2018 Apr 20.

Department of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine, Seoul, 03722, Korea.

Hypoxic-ischemic (HI) brain injury and spinal cord injury (SCI) lead to extensive tissue loss and axonal degeneration. The combined application of the polymer scaffold and neural progenitor cells (NPCs) has been reported to enhance neural repair, protection and regeneration through multiple modes of action following neural injury. This study investigated the reparative ability and therapeutic potentials of biological bridges composed of human fetal brain-derived NPCs seeded upon poly(glycolic acid)-based scaffold implanted into the infarction cavity of a neonatal HI brain injury or the hemisection cavity in an adult SCI. Read More

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http://www.nature.com/articles/s12276-018-0054-9
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http://dx.doi.org/10.1038/s12276-018-0054-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938022PMC
April 2018
4 Reads

Neurological complications of Zika virus infection.

Expert Rev Anti Infect Ther 2018 05 26;16(5):399-410. Epub 2018 Apr 26.

a Neurology Department , Raigmore Hospital , Inverness , UK.

Introduction: Zika virus (ZIKV) disease is a vector-borne infectious disease transmitted by Aedes mosquitoes. Recently, ZIKV has caused outbreaks in most American countries. Areas covered: Publications about neurological complications of ZIKV infection retrieved from pubmed searchers were reviewed, and reference lists and relevant articles from review articles were also examined. Read More

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https://www.tandfonline.com/doi/full/10.1080/14787210.2018.1
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http://dx.doi.org/10.1080/14787210.2018.1466702DOI Listing
May 2018
19 Reads

Autonomic Regulation and Ventricular Arrhythmias.

Curr Treat Options Cardiovasc Med 2018 Apr 7;20(5):38. Epub 2018 Apr 7.

UCLA Cardiac Arrhythmia Center and Neurocardiology Research Center of Excellence, Los Angeles, CA, USA.

Autonomic nervous system (ANS) has a crucial role of regulating cardiac function in the physiological state and contributes to the pathogenesis of arrhythmias in the diseased state. The cardiac neuraxis consists of multiple feedback loops consisting of efferent and afferent limbs, mediating neurotransmission to and from the heart. Efferent parasympathetic neurotransmission is mediated by the vagus nerve, while paravertebral sympathetic ganglia relay efferent sympathetic neurotransmission to the heart. Read More

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http://link.springer.com/10.1007/s11936-018-0633-z
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http://dx.doi.org/10.1007/s11936-018-0633-zDOI Listing
April 2018
3 Reads

Spinal cord infarction: Clinical and imaging insights from the periprocedural setting.

J Neurol Sci 2018 May 17;388:162-167. Epub 2018 Mar 17.

Mayo Clinic, Department of Neurology, Rochester, USA. Electronic address:

Objective: Describe the range of procedures associated with spinal cord infarction (SCI) as a complication of a medical/surgical procedure and define clinical and imaging characteristics that could be applied to help diagnose spontaneous SCI, where the diagnosis is often less secure.

Methods: We used an institution-based search tool to identify patients evaluated at Mayo Clinic, Rochester, MN from 1997 to 2016 with a periprocedural SCI. We performed a descriptive analysis of clinical features, MRI and other laboratory findings, and outcome. Read More

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http://dx.doi.org/10.1016/j.jns.2018.03.029DOI Listing
May 2018
7 Reads

Vascular Disorders of the Spinal Cord.

Continuum (Minneap Minn) 2018 Apr;24(2, Spinal Cord Disorders):407-426

Purpose Of Review: Prompt recognition and timely management of vascular disorders of the spinal cord can improve patient outcomes. This article provides contemporary and practical knowledge about the most common vascular myelopathies.

Recent Findings: New studies have provided additional information on the risk factors and impact of neurologic monitoring on perioperative spinal cord infarction. Read More

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http://dx.doi.org/10.1212/CON.0000000000000595DOI Listing
April 2018
5 Reads

Anterior spinal cord syndrome-"owl's eye sign".

J Gen Fam Med 2018 03 6;19(2):63-64. Epub 2018 Feb 6.

Department of Gastroenterology National Hospital Organization Fukuyama Medical Center Fukuyama, Hiroshima Japan.

Magnetic resonance imaging revealing abnormally high signal intensity in the thoracic cord, extending from T5 to T10 on a sagittal T2-weighted image (Figure 1A). An axial T2-weighted image showing "owl's eye sign" involving central-anterior cord (Figure 1B), which was consistent with anterior spinal cord syndrome. Read More

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http://dx.doi.org/10.1002/jgf2.156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867157PMC
March 2018
1 Read

Injury of the Prefrontocaudate Tract in a Patient with a Bilateral Caudate Infarct

Balkan Med J 2018 07 28;35(4):344-345. Epub 2018 Mar 28.

Department of Physical Therapy, College of Health Sciences, Catholic University of Pusan, Busan, South Korea

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http://dx.doi.org/10.4274/balkanmedj.2018.0201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060979PMC
July 2018
8 Reads

Novel Vertebral Artery Flow Reversal Method for Preventing Ischemic Complication during Endovascular Intervention.

J Stroke Cerebrovasc Dis 2018 Jul 16;27(7):e144-e147. Epub 2018 Mar 16.

Neuroendovascular Therapy Center, Aichi Medical University, Nagakute, Aichi, Japan.

Background And Purpose: We report a secure endovascular approach for the treatment of vascular lesions of the posterior circulation. Even if a large profile guide catheter is wedged in the unilateral vertebral artery (VA), our VA flow reversal method can prevent ischemic complications, including the spinal cord infarction.

Case Presentation: The patient was a 64-year-old woman who had been followed up for arteriovenous malformation (AVM) and an unruptured aneurysm of the basilar artery-superior cerebellar artery bifurcation. Read More

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2018.02.036DOI Listing
July 2018
2 Reads

Spinal Cord Infarction in the Region of the Posterior Spinal Artery After Embolization for Vertebral Artery Dissection.

Oper Neurosurg (Hagerstown) 2018 Dec;15(6):701-710

Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.

Background: Endovascular surgery for vertebral artery dissections (VADs) carries the risk of spinal cord infarction (SCI). Although SCI in the region of the anterior spinal artery (ASA) has been reported, SCI in the region of the posterior spinal artery (PSA) is rare.

Objective: To investigate PSA infarction after endovascular surgery for VAD. Read More

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http://dx.doi.org/10.1093/ons/opy026DOI Listing
December 2018
4 Reads

Spinal cord infarction caused by sacral canal epidural steroid injection: A case report.

Medicine (Baltimore) 2018 Mar;97(11):e0111

Rehabilitation Department of Chinese PLA 163 Hospital, Changsha, Hunan, China.

Rationale: Spinal cord infarction is one of the complications of epidural steroid injections (ESIs), but has only been reported in cervical vertebra by transforaminal injection and lumbar vertebra by transforaminal injection; and up to now, there is no reporting about spinal cord infarction caused by caudal injection. Here, we report a case.

Patient Concerns: A 52-year-old man was admitted to our hospital. Read More

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http://dx.doi.org/10.1097/MD.0000000000010111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882383PMC
March 2018
5 Reads