2,457 results match your criteria Spatial Neglect


Mental representation of a line when patients with left unilateral spatial neglect bisect it: A study with an endpoint reproduction task.

J Neuropsychol 2021 Jun 22. Epub 2021 Jun 22.

Department of Rehabilitation Medicine, Sapporo Medical University School of Medicine, Hokkaido, Japan.

Patients with left unilateral spatial neglect (USN) typically place the subjective midpoint to the right of the objective centre. Based on the previous findings (e.g. Read More

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Self-efficacy as a crucial psychological predictor of treatment adherence among elderly people living with HIV: analyses based on the health belief model.

AIDS Care 2021 Jun 22:1-7. Epub 2021 Jun 22.

Department of Health Related Social and Behavioral Science, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, People's Republic of China.

Medication adherence to antiretroviral therapy (ART) among elderly people living with HIV (PLWH) is of serious concern. Our study aimed to understand the medication adherence of elderly PLWH under ART based on the health belief model (HBM). A baseline survey with a total of 529 elderly PLWH was conducted in Sichuan. Read More

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Deficits of hierarchical predictive coding in left spatial neglect.

Brain Commun 2021 4;3(2):fcab111. Epub 2021 Jun 4.

Dipartimento di Psicologia 39, Sapienza Università di Roma, 00185 Roma, Italy.

Right brain-damaged patients with unilateral spatial neglect fail to explore the left side of space. Recent EEG and clinical evidence suggests that neglect patients might suffer deficits in predictive coding, i.e. Read More

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Updating beliefs beyond the here-and-now: the counter-factual self in anosognosia for hemiplegia.

Brain Commun 2021 21;3(2):fcab098. Epub 2021 May 21.

Department of Clinical, Educational and Health Psychology, University College London, London WC1E 6BT, UK.

The syndrome of anosognosia for hemiplegia, or the lack of awareness for one's paralysis following right hemisphere stroke, can provide unique insights into the neurocognitive mechanisms of self-awareness. Yet it remains unclear whether anosognosia for hemiplegia is a modality-specific deficit of sensorimotor monitoring, or whether domain-general processes of attention and belief-updating converge to cause anosognosia for hemiplegia. Using a Bayesian learning framework, we formalized and empirically investigated the hypothesis that failures to update anosognosic beliefs can be explained by abnormalities in the relative uncertainty (i. Read More

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Patients with lesions to the intraparietal cortex show greater proprioceptive realignment after prism adaptation: Evidence from open-loop pointing and manual straight ahead.

Neuropsychologia 2021 Jun 15;158:107913. Epub 2021 Jun 15.

School of Psychology, Brigantia Building, University of Bangor, Penrallt Rd, Bangor, Gwynedd, LL57 2AS, UK. Electronic address:

Reaching toward a target viewed through laterally refracting prisms results in adaptation of both visual and (limb) proprioceptive spatial representations. Common ways to measure adaptation after-effect are to ask a person to point straight ahead with their eyes closed ("manual straight ahead", MSA), or to a seen target using their unseen hand ("open-loop pointing", OLP). MSA measures changes in proprioception only, whereas OLP measures the combined visual and proprioceptive shift. Read More

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A low-dimensional structure of neurological impairment in stroke.

Brain Commun 2021 3;3(2):fcab119. Epub 2021 Jun 3.

Department of Neuroscience, University of Padova, Padova 35100, Italy.

Neurological deficits following stroke are traditionally described as syndromes related to damage of a specific area or vascular territory. Recent studies indicate that, at the population level, post-stroke neurological impairments cluster in three sets of correlated deficits across different behavioural domains. To examine the reproducibility and specificity of this structure, we prospectively studied first-time stroke patients ( = 237) using a bedside, clinically applicable, neuropsychological assessment and compared the behavioural and anatomical results with those obtained from a different prospective cohort studied with an extensive neuropsychological battery. Read More

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Interaction between spatial neglect and attention deficit in patients with right hemisphere damage.

Cortex 2021 May 19;141:331-346. Epub 2021 May 19.

Department of Rehabilitation for the Movement Functions, Research Institute of National Rehabilitation Center for Persons with Disabilities, Tokorozawa, Saitama, Japan; Regenerative Rehabilitation Section of Department of Rehabilitation, Hospital of National Rehabilitation Center for Persons with Disabilities, Saitama, Japan. Electronic address:

Unilateral spatial neglect (USN) was originally regarded as a parietal syndrome, but it has become evident that USN is a disturbance in the widespread attention network. Here, we focused on an interaction between spatial neglect and non-spatial aspect of attention deficit, and aimed to establish a novel evaluation approach based on the characteristics of the spatial distribution of reaction times. We tested 174 patients with right hemisphere damage and divided them based on their prescreening scores on the Behavioral Inattention Test (BIT): (1) USN++ (n = 79: BIT<131), (2) USN+ (n = 47: BIT≥131 with history of USN), and (3) RHD (n = 48: without neglect symptom). Read More

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Determination of Abundant Metabolite Matrix Adducts Illuminates the Dark Metabolome of MALDI-Mass Spectrometry Imaging Datasets.

Anal Chem 2021 Jun 7;93(24):8399-8407. Epub 2021 Jun 7.

Max Planck Institute for Marine Microbiology, Celsiusstrasse 1, 28359 Bremen, Germany.

Spatial metabolomics using mass spectrometry imaging (MSI) is a powerful tool to map hundreds to thousands of metabolites in biological systems. One major challenge in MSI is the annotation of / values, which is substantially complicated by background ions introduced throughout the chemicals and equipment used during experimental procedures. Among many factors, the formation of adducts with sodium or potassium ions, or in case of matrix-assisted laser desorption ionization (MALDI)-MSI, the presence of abundant matrix clusters strongly increases total / peak counts. Read More

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Isolating Patterns in Open Reaction-Diffusion Systems.

Bull Math Biol 2021 Jun 4;83(7):82. Epub 2021 Jun 4.

Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Andrew Wiles Building, Radcliffe Observatory Quarter, Woodstock Road, Oxford, OX2 6GG, UK.

Realistic examples of reaction-diffusion phenomena governing spatial and spatiotemporal pattern formation are rarely isolated systems, either chemically or thermodynamically. However, even formulations of 'open' reaction-diffusion systems often neglect the role of domain boundaries. Most idealizations of closed reaction-diffusion systems employ no-flux boundary conditions, and often patterns will form up to, or along, these boundaries. Read More

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Body size perception in stroke patients with paresis.

PLoS One 2021 4;16(6):e0252596. Epub 2021 Jun 4.

Division of Neuropsychology, Center of Neurology, Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.

Recent studies have suggested that people's intent and ability to act also can influence their perception of their bodies' peripersonal space. Vice versa one could assume that the inability to reach toward and grasp an object might have an impact on the subject's perception of reaching distance. Here we tested this prediction by investigating body size and action capability perception of neurological patients suffering from arm paresis after stroke, comparing 32 right-brain-damaged patients (13 with left-sided arm paresis without additional spatial neglect, 10 with left-sided arm paresis and additional spatial neglect, 9 patients had neither arm paresis nor neglect) and 27 healthy controls. Read More

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Perfusion Imaging: An Advection Diffusion Approach.

IEEE Trans Med Imaging 2021 Jun 4;PP. Epub 2021 Jun 4.

Perfusion imaging is of great clinical importance and is used to assess a wide range of diseases including strokes and brain tumors. Commonly used approaches for the quantitative analysis of perfusion images are based on measuring the effect of a contrast agent moving through blood vessels and into tissue. Contrast-agent free approaches, for example, based on intravoxel incoherent motion and arterial spin labeling, also exist, but are so far not routinely used clinically. Read More

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InfoColorizer: Interactive Recommendation of Color Palettes for Infographics.

IEEE Trans Vis Comput Graph 2021 Jun 1;PP. Epub 2021 Jun 1.

When designing infographics, general users usually struggle with getting desired color palettes using existing infographic authoring tools, which sometimes sacrifice customizability, require design expertise, or neglect the influence of elements? spatial arrangement. We propose a data-driven method that provides flexibility by considering users? preferences, lowers the expertise barrier via automation, and tailors suggested palettes to the spatial layout of elements. We build a recommendation engine by utilizing deep learning techniques to characterize good color design practices from data, and further develop InfoColorizer, a tool that allows users to obtain color palettes for their infographics in an interactive and dynamic manner. Read More

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Spatio-Temporal-Spectral Hierarchical Graph Convolutional Network With Semisupervised Active Learning for Patient-Specific Seizure Prediction.

IEEE Trans Cybern 2021 May 25;PP. Epub 2021 May 25.

Graph theory analysis using electroencephalogram (EEG) signals is currently an advanced technique for seizure prediction. Recent deep learning approaches, which fail to fully explore both the characterizations in EEGs themselves and correlations among different electrodes simultaneously, generally neglect the spatial or temporal dependencies in an epileptic brain and, thus, produce suboptimal seizure prediction performance consequently. To tackle this issue, in this article, a patient-specific EEG seizure predictor is proposed by using a novel spatio-temporal-spectral hierarchical graph convolutional network with an active preictal interval learning scheme (STS-HGCN-AL). Read More

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Exploring the time-course and the reference frames of adaptation to optical prisms and its aftereffects.

Cortex 2021 Apr 24;141:16-35. Epub 2021 Apr 24.

Department of Psychology, University of Milano-Bicocca, Milan, Italy; Neuropsychological Laboratory, Istituto di Ricovero e Cura a Carattere Scientifico Istituto Auxologico Italiano, Milan, Italy. Electronic address:

Prism adaptation (PA) is used to investigate visuo-motor plasticity and to rehabilitate the syndrome of Unilateral Spatial Neglect (USN). After PA, participants show aftereffects (AEs), contralateral to the side of the optical displacement in several tasks. This study explored the features of these AEs, specifically the "egocentric" versus "allocentric, object-based", reference frames involved, and their time course. Read More

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Can prism adaptation effects generalize to wheelchair maneuvering?

NeuroRehabilitation 2021 May 6. Epub 2021 May 6.

Department of Psychology & Neuroscience, Dalhousie University, Halifax, Nova Scotia, CA, Canada.

Background: While prism adaptation (PA) has been recognized as a promising tool for treating spatial neglect, implementation as a standard treatment in clinical care has been lagging. Limited evidence for the generalization of after-effects to everyday activities has been a barrier towards implementation.

Objectives: This study examined whether a home-friendly standardized PA protocol (Peg-the-Mole, PTM) induces after-effects that can transfer to wheelchair maneuvering. Read More

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Wigner function-based modeling and propagation of partially coherent light in optical systems with scattering surfaces.

Opt Express 2021 May;29(10):14985-15000

Light scattering from residual manufacturing errors of optical surfaces has a large impact on the image quality of optical systems. Classical ray-based methods to simulate surface scattering in optical systems depend on statistical models of surface errors and neglect the wave properties of light, which prohibit the integration of statistical surface error models with beam propagation methods. Additionally, the impact of multiple scattering from different frequency components of surface errors cannot be easily modelled by existing methods. Read More

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Consecutive and temporally distant perseverations after right brain damage: A prospective study.

Neuropsychology 2021 Mar;35(3):310-322

Department of Human Sciences, LUMSA University.

Right brain-damaged patients may show omissions and/or additional marks in target cancellation. The latter is classified as perseverative behavior and has been attributed to defective response inhibition or attentional disengagement deficit. This study aimed at (a) verifying that consecutive (immediate) and return (temporally distant) motor perseverations could be due to different mechanisms; (b) investigating the relationships among different types of perseveration (e. Read More

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Unilateral Spatial Neglect without Hemiplegia: The Output-Mode Effect Revisited.

J Stroke Cerebrovasc Dis 2021 Jul 4;30(7):105777. Epub 2021 May 4.

Department of Neurological Rehabilitation, Loewenstein Rehabilitation Medical Center, 278 Ahuza, Raanana 4355840, Israel; Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel. Electronic address:

Background: The occurrence of unilateral spatial neglect (USN) in non-hemiplegic right-hemisphere damaged patients is rare. Earlier studies of such patients revealed a significant advantage when typical neglect tests were performed by the patient's left hand as compared to the dominant right hand. The mechanism underlying this "output-mode effect" remains elusive. Read More

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Spatial neglect treatment: The brain's spatial-motor Aiming systems.

Neuropsychol Rehabil 2021 May 3:1-27. Epub 2021 May 3.

Department of Neurology, University of California Irvine, Irvine, CA, USA.

Animal and human literature supports spatial-motor "Aiming" bias, a frontal-subcortical syndrome, as a core deficit in spatial neglect. However, spatial neglect treatment studies rarely assess Aiming errors. Two knowledge gaps result: spatial neglect rehabilitation studies fail to capture the impact on motor-exploratory aspects of functional disability. Read More

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Deep Hough Transform for Semantic Line Detection.

IEEE Trans Pattern Anal Mach Intell 2021 May 3;PP. Epub 2021 May 3.

We focus on a fundamental task of detecting meaningful line structures, a.k.a. Read More

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The presence of semantic content in a visual recognition memory task reduces the severity of neglect.

Neuropsychologia 2021 Jul 24;157:107860. Epub 2021 Apr 24.

Neurobiology Department, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, 91904, Israel; The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem, Jerusalem, 91904, Israel.

Patients with right hemisphere damage often show a lateral bias when asked to report the left side of mental images held in visual working memory (i.e. representational neglect). Read More

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Pathological structure of visuospatial neglect: A comprehensive multivariate analysis of spatial and non-spatial aspects.

iScience 2021 Apr 16;24(4):102316. Epub 2021 Mar 16.

Department of Rehabilitation for the Movement Functions, Research Institute of National Rehabilitation Center for Persons with Disabilities, 4-1 Namiki, Tokorozawa, Saitama, Japan.

Visuospatial neglect (VSN) is a neurological syndrome of higher brain functions in which an individual fails to detect stimuli on a space that is contralateral to a hemispheric lesion. We performed a comprehensive multivariate analysis based on the principal component analysis (PCA) and cluster analysis in patients with right hemisphere stroke and then performed a determination of different elements of VSN. PCA-based cluster analysis detected distinct aspects of VSN as follows: cluster 1: low arousal and attention state, cluster 2: exogenous neglect, cluster 3: spatial working memory (SWM) deficit. Read More

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The posterior parietal cortex processes visuo-spatial and extra-retinal information for saccadic remapping: A case study.

Cortex 2021 Jun 19;139:134-151. Epub 2021 Mar 19.

IMPACT Team, Lyon Neuroscience Research Center, INSERM, U1028, CNRS, UMR5292, University of Lyon, Bron Cedex, France. Electronic address:

Optimally collecting information and controlling behaviour require that we constantly scan our visual environment through eye movements. How the dynamic interaction between short-lived retinal images and extra-retinal signals of eye motion results in our subjective experience of visual stability remains a major issue in Cognitive Neuroscience. The present study aimed to assess and determine the nature of the contribution of the posterior parietal cortex (PPC) to the saccadic remapping mechanisms which contribute to such perceptual visual constancy. Read More

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Video-Oculography During Free Visual Exploration to Detect Right Spatial Neglect in Left-Hemispheric Stroke Patients With Aphasia: A Feasibility Study.

Front Neurosci 2021 29;15:640049. Epub 2021 Mar 29.

Perception and Eye Movement Laboratory, Department of Neurology, University of Bern, Bern, Switzerland.

Spatial neglect has been shown to occur in 17-65% of patients after acute left-hemispheric stroke. One reason for this varying incidence values might be that left-hemispheric stroke is often accompanied by aphasia, which raises difficulties in assessing attention deficits with conventional neuropsychological tests entailing verbal instructions. Video-oculography during free visual exploration (FVE) requires only little understanding of simple non-verbal instruction and has been shown to be a sensitive and reliable tool to detect spatial neglect in patients with right-hemispheric stroke. Read More

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Bálint syndrome.

Handb Clin Neurol 2021 ;178:233-255

Trajectoires, Centre de Recherche en Neurosciences de Lyon, Inserm, CNRS, Université Lyon 1, Bron, France; Plateforme "Mouvement et Handicap", Hôpital Henry-Gabrielle, Hospices Civils de Lyon, Saint-Genis-Laval, France.

This chapter starts by reviewing the various interpretations of Bálint syndrome over time. We then develop a novel integrative view in which we propose that the various symptoms, historically reported and labeled by various authors, result from a core mislocalization deficit. This idea is in accordance with our previous proposal that the core deficit of Bálint syndrome is attentional (Pisella et al. Read More

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January 2021

Prism adaptation treatment for spatial neglect post brain tumour removal: A case report.

Hong Kong J Occup Ther 2020 Jun 16;33(1):25-29. Epub 2020 Jun 16.

University of Texas Medical Branch, USA.

Purpose/aim: Spatial neglect is caused by damage to neural networks critical for spatial attention. Spatial neglect without proper treatment impedes rehabilitation outcomes. Prism adaptation treatment, a visuomotor protocol, has been used with stroke survivors with spatial neglect to improve function. Read More

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Effect of Prism Adaptation Therapy on the Activities of Daily Living and Awareness for Spatial Neglect: A Secondary Analysis of the Randomized, Controlled Trial.

Brain Sci 2021 Mar 9;11(3). Epub 2021 Mar 9.

Department of Rehabilitation Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.

Background: Rehabilitation for unilateral spatial neglect (USN) using prism adaptation (PA) is one of the most widely used methods, and the effectiveness of PA is well-evidenced. Although the effect of PA generalized various neglect symptoms, the effectiveness for some aspects of neglect is not fully proven. The Catherine Bergego Scale (CBS) was developed to identify problems with the activities of daily living (ADL) caused by USN. Read More

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A novel 3-choice touchscreen task to examine spatial attention and orienting responses in rodents.

eNeuro 2021 Mar 29. Epub 2021 Mar 29.

Graduate Program in Neuroscience, The University of Western Ontario, London, Ontario, Canada

Mammalian orienting behaviour consists of coordinated movements of the eyes, head, pinnae, vibrissae, or body to attend to an external stimulus. The present study aimed to develop a novel operant task using a touch-screen system to measure spatial attention. In this task, rats were trained to nose-poke a light stimulus presented in one of three locations. Read More

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Virtual Reality Tools for Assessing Unilateral Spatial Neglect: A Novel Opportunity for Data Collection.

J Vis Exp 2021 03 10(169). Epub 2021 Mar 10.

Department of Neurology, University of Pennsylvania; Laboratory for Cognition and Neural Stimulation, University of Pennsylvania; Department of Physical Medicine and Rehabilitation, University of Pennsylvania.

Unilateral spatial neglect (USN) is a syndrome characterized by inattention to or inaction in one side of space and affects between 23-46% of acute stroke survivors. The diagnosis and characterization of these symptoms in individual patients can be challenging and often requires skilled clinical staff. Virtual reality (VR) presents an opportunity to develop novel assessment tools for patients with USN. Read More

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Neglect in temporal domain: Amelioration following a prismatic adaptation treatment and implications in everyday life. A single case study.

Brain Cogn 2021 06 25;150:105712. Epub 2021 Mar 25.

Department of Psychology, University of Bologna, Viale Berti Pichat 5, 40127 Bologna, Italy; Maugeri Clinical Scientific Institutes - IRCCS of Castel Goffredo, Via Ospedale 36, 46042 Castel Goffredo, Mantova, Italy. Electronic address:

As in line bisection, in time bisection, neglect patients fail to process the first/left part of time representation (Mental-Time-Line-MTL) resulting in a rightward shift of the interval midpoint. A leftward shift of spatial attention after one session of prismatic-adaptation (PA) reduces this deficit. The impact on daily life of time deficit is little investigated in neglect. Read More

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