6,139 results match your criteria Spasmodic Dysphonia

The Patho-Neurophysiological Basis and Treatment of Focal Laryngeal Dystonia: A Narrative Review and Two Case Reports Applying TMS over the Laryngeal Motor Cortex.

J Clin Med 2022 Jun 15;11(12). Epub 2022 Jun 15.

Department of Medical Chemistry and Biochemistry, University of Split School of Medicine, 21000 Split, Croatia.

Focal laryngeal dystonia (LD) is a rare, idiopathic disease affecting the laryngeal musculature with an unknown cause and clinically presented as adductor LD or rarely as abductor LD. The most effective treatment options include the injection of botulinum toxin (BoNT) into the affected laryngeal muscle. The aim of this narrative review is to summarize the patho-neuro-physiological and genetic background of LD, as well as the standard recommended therapy (BoNT) and pharmacological treatment options, and to discuss possible treatment perspectives using neuro-modulation techniques such as repetitive transcranial magnetic stimulation (rTMS) and vibrotactile stimulation. Read More

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Neurectomy and Myomectomy for Treatment of Spasmodic Dysphonia.

J Voice 2022 Jun 20. Epub 2022 Jun 20.

Department of Otolaryngology - Head and Neck Surgery, Senior Associate Dean for Clinical Academic Specialties, Drexel University College of Medicine, Director of Otolaryngology, and Communication Sciences Research, Lankenau Institute for Medical Research, Philadelphia, Pennsylvania. Electronic address:

Spasmodic dysphonia (SD) is a debilitating neurological disorder affecting the muscles of voice production. Sudden involuntary movements of the vocal folds lead to phonatory breaks and to forced, strained, and strangled voice quality in adductor SD, or breathy breaks in abductor SD. There is currently no cure for spasmodic dysphonia, and the gold standard for treatment is the injection of botulinum toxin in small amounts to the intrinsic laryngeal musculature. Read More

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Rituximab in Refractory Myositis and Acute Neuropathy Secondary to Checkpoint Inhibitor Therapy.

Cureus 2022 May 19;14(5):e25129. Epub 2022 May 19.

Department of Neurology, University of Florida, Gainesville, USA.

Checkpoint inhibitor immunotherapies have been one of the latest advances through the last decade in the treatment of various cancers. As their use is increasing so is the knowledge of their complications which can affect various organ systems including the central and peripheral nervous systems. Management of these complications requires stopping the offending agent and in some cases treating with immunosuppressive agents like intravenous steroids. Read More

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Listeners' attitudes towards voice disorders: An interaction between auditory and visual stimuli.

J Commun Disord 2022 Jun 18;99:106241. Epub 2022 Jun 18.

Centre for Speech and Language Sciences, Department of Rehabilitation Sciences, Ghent University, Ghent, Belgium; Faculty of Humanities, Department of Speech-Language Pathology and Audiology, University of Pretoria, Pretoria, South Africa.

Objective: People with dysphonia are judged more negatively than peers with normal vocal quality. This preliminary study aims to (1) investigate correlations between both auditory-perceptual and objective measures of vocal quality of dysphonic and non-dysphonic speakers and attitudes of listeners, and (2) discover whether these attitudes towards people with dysphonia vary for different types of stimuli: auditory (A) stimuli and combined auditory-visual (AV) stimuli. Visual (V) stimuli were included as a control condition. Read More

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Outcomes of endoscopic percutaneous suture lateralization for neonatal and infantal bilateral vocal ford paralysis.

Braz J Otorhinolaryngol 2022 Jun 9. Epub 2022 Jun 9.

Children's Hospital of Fudan University, Department of Otolaryngology-Head and Neck Surgery, Shanghai, China.

Objective: Bilateral Vocal Fold Paralysis (BVFP) is a rare but significant resource of respiratory distress in neonates and infants. The objective of this study was to evaluate the efficacy and functional outcomes of Endoscopic Percutaneous Suture Lateralization (EPSL) for the treatment of BVFP in neonates and infants.

Methods: A case series study of nine patients undergoing EPSL for BVFP between January 2019 and June 2021 was conducted. Read More

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[Analysis of vocal fold vibration characteristics of spasmodic dysphonia by laryngeal high speed photography combined with glottis area wave].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2022 Jun;57(6):706-710

Department of Voice, Zhongshan Hospital of Xiamen University, Xiamen 361004, China.

To analyze the characteristics of vocal fold vibration of normal people and patients with spasmodic dysphonia (SD) using laryngeal high speed videoendoscopy combined with glottal area wave analysis. This prospective study examined twenty healthy subjects (10 males and 10 females), 12 patients with adductor spasmodic dysphonia(AdSD) (2 males,10 females)as AdSD group and 2 patients with abductor spasmodic dysphonia(AbSD) (2 males) as AbSD group. Twelve of healthy subjects (2 males,10 females) were selected as control group according to AdSD group gender match. Read More

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[Balloon catheter inflation with alkalinized lidocaine reduces post-operative laryngeal pain: a prospective, randomized controlled clinical trial].

Pan Afr Med J 2022 21;41:230. Epub 2022 Mar 21.

Service d'Anesthésie-Réanimation Chirurgicale, Centre Hospitalier Universitaire Habib Bourguiba Sfax, Sfax, Tunisie.

Introduction: post-operative laryngeal pain (POLP) is frequent and embarrassing. The purpose of this study is to assess the efficacy of endotracheal tube balloon (ETB) inflation with alkalinized lidocaine in the prevention of the POLP.

Methods: we conducted a prospective, single-center, double-blind, randomized study including patients undergoing general anesthesia with tracheal intubation (OTI) with an expected duration of less than 240 min. Read More

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Paracrine Effects of Adipose-Derived Cellular Therapies in an in Vitro Fibrogenesis Model of Human Vocal Fold Scarring.

J Voice 2022 Jun 13. Epub 2022 Jun 13.

Division of Phoniatrics, ENT University Hospital Graz, Medical University of Graz, Graz, Austria.

Objectives/hypothesis: Vocal folds (VF) scarring leads to severe dysphonia which negatively impacts daily life of patients. Current therapeutic options are limited due in large part to the high complexity of the micro-structure of the VF. Innovative therapies derived from adipose tissue such as stromal vascular fraction (SVF) or adipose derived stromal/ stem cells (ASC) are currently being evaluated in this indication and paracrine anti-fibrotic effects are considered as predominant mechanisms. Read More

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Intraoperative computed tomography imaging for laryngoplasty.

Auris Nasus Larynx 2022 Jun 11. Epub 2022 Jun 11.

Department of Otolaryngology-Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Objectives: Intraoperative cone beam computed tomography (CBCT) imaging has the potential to facilitate the surgical procedure. The current preliminary retrospective chart review investigated the benefits of intraoperative CBCT during laryngoplasty.

Method: This study examined 26 cases that underwent intraoperative CBCT imaging during laryngoplasty, with one patient who counted twice due to first and revision surgery. Read More

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Spasmodic dysphonia: An overview of clinical features and treatment options.

Tetsuji Sanuki

Auris Nasus Larynx 2022 Jun 11. Epub 2022 Jun 11.

Department of Otolaryngology-Head and Neck Surgery, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi Mizuho-Cho, Mizuho-Ku, Nagoya, Japan. Electronic address:

Spasmodic dysphonia (SD) is considered a rare focal laryngeal dystonia characterized by task-specific voice dysfluency resulting from selective intrinsic laryngeal musculature hyperfunction. Symptoms may be attenuated by a sensory trick. Although SD can be seen at times in generalized dystonia syndrome, it is typically a sporadic phenomenon, and the involvement of the laryngeal adductor muscles is more common than that of the abductor muscles. Read More

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Non-interventional Pilot Study Evaluating the Efficacy and Safety of Lysozymebased Therapy in Patients with Non-infectious Sore Throat.

Acta Med Acad 2022 Apr;51(1):1-13

Scientific Research Unit, Bosnalijek d.d., Bosnia and Herzegovina; Department for Biochemistry and Clinical Analysis, Faculty of Pharmacy, University of Sarajevo, Bosnia and Herzegovina; School of Medicine, University of Mostar, Bosnia and Herzegovina.

Objective: This study aimed to evaluate the efficacy and safety of lysozyme-based oral antiseptic in the therapy of non-infectious sore throat in teachers.

Materials And Methods: A non-interventional, prospective, pilot study was conducted with two examinations. The first was performed as part of a general medical examination. Read More

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Laryngopharyngeal Reflux: Effect of Race and Insurance Status on Symptomology.

Ann Otol Rhinol Laryngol 2022 Jun 11:34894221100025. Epub 2022 Jun 11.

Rush University Medical Center, Chicago, IL, USA.

Objectives: Laryngopharyngeal reflux (LPR) is an extraesophageal variant of gastroesophageal reflux disease associated with intermittent dysphonia, throat-clearing, and chronic cough. This study aims to evaluate the impact of race and insurance status on symptoms often attributable to LPR.

Methods: Retrospective review of all patients with suspected LPR from 2017 to 2019 was performed at a tertiary care center. Read More

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Voice Quality Analysis of Reinke's Edema According to Recent New Classification.

J Voice 2022 Jun 8. Epub 2022 Jun 8.

Department of Sense Organs, Sapienza University of Rome, Rome, Italy.

Objective: Reinke's edema is a benign laryngeal disease characterized by inflammation and swelling of the superficial layer of the lamina propria of the vocal fold, known as Reinke's space. The aim of this study was to evaluate the quality of voice by quantitative acoustic measurements in patients affected by RE according to new classification proposed by de Vincentiis.

Study Design: Prospective case-control. Read More

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A Preliminary Study on the Effect of Bhramari Pranayama on Voice of Prospective Singers.

J Voice 2022 Jun 8. Epub 2022 Jun 8.

Department of Swasthavritta and Yoga, Shri B M Kankanwadi Ayurveda Mahavidyalaya PG Studies and Medical Research Centre, KLE Academy of Higher Education and Research, Belagavi, Karnataka, India.

Introduction: Bhramari Pranayama (BP) is a yogic breathing technique that involves producing a vibrating constant pitch sound emulating the buzzing of bumblebee. Since BP deals with breathing and humming in the sustained pitch, it is hypothesized that it can have implications for improving voice quality in individuals. However, there is a dearth of research available to support this assumption. Read More

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[Clinical and paraclinical profile of autoimmune myasthenia gravis in Ouagadougou, Burkina Faso].

Med Trop Sante Int 2021 12 11;1(4). Epub 2021 Nov 11.

CHU Yalgado Ouédraogo de Ouagadougou, Unité de formation et de recherches des sciences de la santé, Université Joseph Ki-Zerbo, Ouagadougou, Burkina Faso.

Introduction: Certain differences in the epidemiological, clinical, paraclinical and evolution profiles of autoimmune myasthenia gravis (AIMG) are increasingly described in patients according to geographic origins. The present study was carried out in order to help characterize the socio-demographic, clinical and paraclinical profile of AIMG in Ouagadougou, Burkina Faso.

Patients And Methods: This was a cross-sectional, descriptive, multicenter, hospital study carried out in Ouagadougou (Burkina Faso), over a period of 5 years 6 months, from March 2015 to September 2019. Read More

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December 2021

Vocal outcomes after COVID-19 infection: acoustic voice analyses, durational measurements, self-reported findings, and auditory-perceptual evaluations.

Eur Arch Otorhinolaryngol 2022 Jun 6. Epub 2022 Jun 6.

Faculty of Medicine, Department of Otolaryngology and Audiology Subdivision, Gazi University, Ankara, Turkey.

Purpose: The ongoing literature suggests that COVID-19 may have a potential impact on voice characteristics during the infection period. In the current study, we explored how the disease deteriorates different vocal parameters in patients who recovered from COVID-19.

Methods: A total of 80 participants, 40 patients with a prior history of COVID-19 (20 male, 20 female) with a mean age of 39. Read More

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Rhabdomyoma in the base of the tongue : A case report.

Int J Surg Case Rep 2022 Jun 25;95:107239. Epub 2022 May 25.

Faculty of Medicine of Damscus University, Damascus, Syria; Al-Mouwasat University Hospital, Damascus, Syria.

Introduction: Rhabdomyomas are benign and rare mesenchymal tumors. They are classified into cardiac and extracardiac. However, the majority of adult subtype, which are extracardiac, tend to occur in the head and neck region. Read More

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Zenker's Diverticulum in Forestier Disease: Chance or Causality?

Iran J Otorhinolaryngol 2022 Mar;34(121):107-112

Department of Biomedicine, Neuroscience and Advanced Diagnostic, University of Palermo, Palermo, Italy.

Introduction: Zenker's diverticulum is an acquired sac-like outpouching of the mucosa and submucosa layers originating at the pharyngoesophageal junction. The predominant symptom of Zenker's diverticulum is dysphagia. Videofluoroscopy confirms the diagnosis. Read More

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An Ex-vivo Model Examining Acoustics and Aerodynamic Effects Following Medialization With and Without Arytenoid Adduction.

Laryngoscope 2022 Jun 2. Epub 2022 Jun 2.

Department of Otolaryngology Head and Neck Surgery, University of Cincinnati, Cincinnati, Ohio, USA.

Objectives/hypothesis: Quantify differences in acoustics and intraglottal flow fields between Thyroplasty Type 1 (TT1) with and without arytenoid adduction (AA) using excised canine larynx model.

Study Design: Basic science experiments using excised larynges.

Methods: Surgical procedures were implemented in eight excised canine larynges. Read More

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Characterization of Mild and Moderate Dysarthria in Parkinson's Disease: Behavioral Measures and Neural Correlates.

Front Aging Neurosci 2022 16;14:870998. Epub 2022 May 16.

Department of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Karolinska University Hospital, Women's Health and Allied Health Professionals, Stockholm, Sweden.

Purpose: Alterations in speech and voice are among the most common symptoms in Parkinson's disease (PD), often resulting in motor speech disorders such as hypokinetic dysarthria. We investigated dysarthria, verbal fluency, executive functions, and global cognitive function in relation to structural and resting-state brain changes in people with PD.

Methods: Participants with mild-moderate PD ( = 83) were recruited within a randomized controlled trial and divided into groups with varying degrees of dysarthria: no dysarthria (noDPD), mild dysarthria (mildDPD), moderate dysarthria (modDPD), and also combined mildDPD and modDPD into one group (totDPD). Read More

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Voice Telerehabilitation in Iatrogenic Unilateral Vocal Fold Paralysis: From Necessity to Opportunity in the COVID-19 Time.

J Voice 2022 May 28. Epub 2022 May 28.

Unità Operativa Complessa di Otorinolaringoiatria, Dipartimento di Scienze dell'Invecchiamento, Neurologiche, Ortopediche e della Testa-Collo, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italia; Sezione di Otorinolaringoiatria, Dipartimento Universitario Testa-Collo e Organi di Senso, Università Cattolica del Sacro Cuore, Roma, Italia.

Objective: To evaluate results of telerehabilitation (TR) during the coronavirus disease 2019 pandemic for the treatment of dysphonia caused by permanent post-thyroidectomy unilateral vocal fold paralysis (UVFP).

Methods: Forty subjects with post-thyroidectomy UVFP (onset <1 month) underwent TR. Videostrobolaryngoscopy, acoustic and perceptual voice analysis and patient self-assessment were carried out in person before, at the end of TR and 6 months later. Read More

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Impact of Voice Therapy on Pediatric Patients With Dysphonia and Vocal Nodules: A Systematic Review.

Cureus 2022 Apr 24;14(4):e24433. Epub 2022 Apr 24.

College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, SAU.

One of the most prevalent pediatric ailments around the world is voice disorders. Around 5-million children suffer from voice disorders, and three out of five of them suffer from vocal nodule-induced persistent dysphonia. Nineteen out of 20 otolaryngologists recommend voice therapies for the treatment of pediatric vocal fold nodules. Read More

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Avicenna's Viewpoints on Dysphonia.

Iran J Med Sci 2022 May;47(3):285-287

Research Institute for Islamic and Complementary Medicine, Iran University of Medical Sciences, Tehran, Iran.

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Primary Laryngeal Tuberculosis Manifesting as Irregular Vocal Fold Lesion.

Turk Arch Otorhinolaryngol 2022 Mar 12;60(1):47-52. Epub 2022 May 12.

Department of Otorhinolaryngology - Head & Neck Surgery, Hospital Canselor Tuanku Muhriz, University Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.

Laryngeal tuberculosis is rare despite its close anatomical and physiological proximity to the lungs. It constitutes less than 1% of extrapulmonary tuberculosis. The symptoms of laryngeal tuberculosis are non-specific and mimic other laryngeal pathologies. Read More

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Survey of Referral Patterns in Southwestern Mainland China: How Do Pediatricians Manage Children with Dysphonia.

J Voice 2022 May 24. Epub 2022 May 24.

Department of Otorhinolaryngology, Head & Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Objective: Voice disorders are common in children and have a negative impact on their quality of life. However, presently, voice assessment and therapy are inaccessible in most pediatric departments of Mainland China. Thus, referring pediatric patients with voice disorders to otolaryngology is warranted for prompt and appropriate treatment. Read More

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Non-alpine primary thyroid angiosarcoma.

Arch Endocrinol Metab 2022 May 25. Epub 2022 May 25.

Departamento de Endocrinologia, Hospital Beatriz Ângelo, Loures, Portugal.

Thyroid angiosarcoma is an extremely rare malignancy, which occurs more frequently in the alpine region, likely associated with iodine deficiency and endemic goiter. This is an aggressive neoplasm that usually harbors a poor prognosis. We report the case of a 49-year-old Portuguese female patient presenting with a large nodule in the anterior neck region, with rapid growth and associated dysphonia. Read More

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[Classification, diagnosis and treatment of spasmodic dysphonia].

P Y Zhuang Y Y Liu

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2022 May;57(5):666-670

Department of Voice, Xiamen University Zhongshan Hospital, Xiamen 361012, China.

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Videolaryngoscopy Findings of the Vocal Health Program in Dysphonic Teachers in the Federal District, Brazil.

Int Arch Otorhinolaryngol 2022 Apr 30;26(2):e243-e249. Epub 2021 Aug 30.

Governo do Distrito Federal, Gerência de Promoção à Saúde do Servidor, Brasília, Distrito Federal, Brazil.

 The high phonatory demand required of teachers is a direct cause of the onset of vocal symptoms and of the development of laryngeal disorders.  To describe the findings of the laryngeal screening performed as part of the Vocal Health Program held in the Federal Distrcit of Brazil in 2014 and 2015.  The study was performed with 361 dysphonic teachers from public schools who attended the laryngeal screening (videolaryngoscopy) part of the program. Read More

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Improving Voice Outcomes after Thyroid Surgery and Ultrasound-Guided Ablation Procedures.

Front Surg 2022 4;9:882594. Epub 2022 May 4.

Sarasota Memorial Health Care System Multidisciplinary Thyroid and Parathyroid Center, Sarasota, Florida, United States.

The field of endocrine surgery has expanded from the traditional open neck approach to include remote access techniques as well as minimally invasive approaches for benign and malignant thyroid nodules. In experienced hands and with careful patient selection, each approach is considered safe, however complications can and do exist. Post-operative dysphonia can have serious consequences to the patient by affecting quality of life and ability to function at work and in daily life. Read More

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The Validity of Cepstral Analysis to Distinguish Dysphonia Between Different Levels of Perceptual Dysphonia in the Persian Vocal Tasks.

J Voice 2022 May 19. Epub 2022 May 19.

Department of Speech Therapy, School of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran.

Objectives/hypothesis: The validity of cepstral analysis (Cepstral Peak Prominence [CPP] and Cepstral Peak Prominence-Smoothed [CPPS]) as an indicator of perceptual dysphonia was investigated in the Persian language STUDY DESIGN: Cross-sectional study.

Methods: A total of 223 participants (159 with and 64 without dysphonia) uttered vowels /a/ and /i/, six standard sentences, and non-standard connected speech. All vocal samples were perceptually evaluated by three raters on a visual analog scale and put into four groups (normal voice, mild, moderate, and severe perpetual dysphonia). Read More

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