257,486 results match your criteria Southern med review[Journal]


Commentary on: Safe Use of Epidural Corticosteroid Injections: Recommendations of the WIP Benelux Work Group, by Van Boxem et al., Pain Practice 2018.

Pain Pract 2018 Dec 16. Epub 2018 Dec 16.

Pain Management Center, Neurocenter of Southern Switzerland, Ospedale Regionale di Lugano, Lugano, Switzerland.

We read with interest the review article of Van Boxem et al. entitled "Safe Use of Epidural Corticosteroid Injections: Recommendations of the WIP Benelux Work Group" published in The Pain Practice Journal. The authors have reviewed the literature involving neurological complications after epidural corticosteroid injections and possible safety measures to prevent major neurologic injuries. Read More

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December 2018

A Survey on the Prevalence and Risk Indicators of Erosive Tooth Wear among Adolescents in Guangzhou, South China.

J Oral Rehabil 2018 Dec 16. Epub 2018 Dec 16.

Southern Medical University, Savaid Medical School, University of the Chinese Academy of Sciences.

Background: Erosive tooth wear (ETW) has become a crucial oral health problem over the decades in China.

Objectives: To explore the prevalence and risk indicators of ETW among adolescents in Guangzhou, south China.

Methods: A cross-sectional survey of 720 participants was conducted in Guangzhou, using an equal-sized, stratified, multistage random sampling approach. Read More

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December 2018

Effect of tree foliage supplementation of tropical grass diet on in vitro digestibility and fermentation, microbial biomass synthesis and enteric methane production in ruminants.

Trop Anim Health Prod 2018 Dec 15. Epub 2018 Dec 15.

Technological Institute of Conkal, Division of Graduate Studies and Research, Avenida Tecnológico s/n, 97345, Conkal, Yucatan, Mexico.

The objective of this study was to evaluate the influence of tree foliage species supplemented in ruminant diets based on Pennisetum purpureum on the in vitro digestibility and fermentation, microbial biomass synthesis and enteric methane production. Seven experimental diets were evaluated, including a control treatment based on P. purpureum (PT) grass, and six additional treatments supplemented with 30. Read More

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December 2018

Association between REM sleep and obstructive sleep apnea in obese and overweight adolescents.

Sleep Breath 2018 Dec 15. Epub 2018 Dec 15.

Children's Hospital Los Angeles, 4650 Sunset Blvd., #83, Los Angeles, CA, USA.

Purpose: Overweight and obese children have demonstrated reduced rapid eye movement (REM) sleep, affecting energy balance regulation and predisposition to weight gain. Obstructive sleep apnea (OSA) is a known cause of decreased REM sleep. The purpose of this study is to examine the association between the percentage of REM sleep, BMI z-score, and OSA severity in overweight and obese adolescents. Read More

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December 2018

Classification of the superior angle of the scapula and its correlation with the suprascapular notch: a study on 303 scapulas.

Surg Radiol Anat 2018 Dec 15. Epub 2018 Dec 15.

Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China.

Purpose: The aims of this study had been to classify the superior angle of the scapula based on morphological features, and to investigate its correlation with the suprascapular notch.

Methods: 303 samples of Chinese dried scapular specimens were collected from the Department of anatomy, Southwest Medical University. According to the anatomical morphological characteristics of the superior angle of the scapula, the morphological classification was performed to explore its correlation with the suprascapular notch (SSN). Read More

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December 2018

Interaction of H. pylori with toll-like receptor 2-196 to -174 ins/del polymorphism is associated with gastric cancer susceptibility in southern China.

Int J Clin Oncol 2018 Dec 15. Epub 2018 Dec 15.

Department of Gastroenterology, Changzhou No. 2 People's Hospital, Xinglong Xiang 29, Changzhou, 213000, Jiangsu, China.

Background: Genetic polymorphisms of Toll-like receptors play important roles in gastric carcinogenesis. The aim of this study was to determine the role of TLR2-196 to -174 ins/del polymorphism in gastric cancer susceptibility and prognosis.

Methods: This study included 520 people from southern China. Read More

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December 2018

Promotion of the mediterranean diet incancer long-survivors by means of the Med-Food Anticancer Program: a pilot study.

Ann Ig 2019 Jan-Feb;31(1):45-51

Discipline of Nutrition and Dietetics, The University of Auckland, New Zealand.

Background: The intervention "Med-Anticancer Food Program" has proven to be effective in promoting the Mediterranean Diet, significantly increasing the Mediterranean Adequacy Index in healthy subjects. There are no studies that have investigated the effectiveness of this intervention in individuals who have had a diagnosis of cancer.

Objective: To perform a pilot study to assess the opportunity of employing the methodology of the Med-Anticancer Food Program in order to encourage "long-term cancer survivors" to adhere to the Mediterranean Diet, as well as healthy people, and this in order to apply the program to larger groups. Read More

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December 2018

Health status, diseases and vaccinations of the homeless in the city of Palermo, Italy.

Ann Ig 2019 Jan-Feb;31(1):21-34

Department of Science for Health Promotion and Mother-Child Care "G. D'Alessandro", University of Palermo, Palermo, Italy.

Introduction: In Italy, as in the rest of the world, the number of homeless people is increasing considerably. Many of them suffer from chronic conditions, mental health problems and addiction to alcohol, drugs or smoking, and need complex medical care. Their health status is often exacerbated by greater difficulty in accessing primary care. Read More

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December 2018

Prospective clinical validation of a meningioma consistency grading scheme: association with surgical outcomes and extent of tumor resection.

Authors:

J Neurosurg 2018 Dec 14:1-5. Epub 2018 Dec 14.

OBJECTIVEThe present study aims to assess the clinical utility of a previously validated intraoperative meningioma consistency grading scale and its association with extent of resection (EOR) and various surgical outcomes.METHODSThe previously validated grading system was prospectively assessed in 127 consecutive patients undergoing open craniotomy for meningioma by multiple neurosurgeons at two high-volume academic hospitals from 2013 to 2016. Consistency grading scores ranging from 1 (soft) to 5 (firm/calcified) were retrospectively analyzed to test for association with surgical outcomes and EOR, categorized as gross-total resection (GTR) or subtotal resection, defined by postoperative MRI. Read More

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December 2018

Linkage between teen mother's childhood adversity and externalizing behaviors in their children at age 11: Three aspects of parenting.

Child Abuse Negl 2018 Dec 13;88:326-336. Epub 2018 Dec 13.

University of Southern California, Suzanne Dworak-Peck School of Social Work, Department of Children, Youth, and Families, Los Angeles, CA, 669 W. 34th Street, 90089, United States.

Background: Experiences of childhood adversity are consistently associated with compromised behavioral health later in life. Less clear is the intergenerational influence of maternal childhood adversity on developmental outcome in children. Completely unknown are the mechanisms linking teen mother's childhood adversity to child developmental outcomes. Read More

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December 2018

An examination of child protective service involvement among children born to mothers in foster care.

Child Abuse Negl 2018 Dec 13;88:317-325. Epub 2018 Dec 13.

Children's Data Network, School of Social Work, School of Social Work, University of Southern California, United States; California Child Welfare Indicators Project, School of Social Welfare, University of California, Berkeley, United States.

Objective: This study identified children born to mothers in foster care and documented Child Protective Service (CPS) involvement among children.

Methods: Probabilistically linked birth and CPS records from California (2009-2012) were used to identify all mothers in foster care on or after conception. Children were followed prospectively using linked records to identify CPS involvement occurring during the first three years of life. Read More

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December 2018

Role of CCL5 and CCR5 gene polymorphisms in epidermal growth factor receptor signalling blockade in metastatic colorectal cancer: analysis of the FIRE-3 trial.

Eur J Cancer 2018 Dec 13;107:100-114. Epub 2018 Dec 13.

Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90033, USA.

Background: Epidermal growth factor receptor signalling blockade increases CCL5 expression that regulates either the anti-tumour immune response or tumour progression. We investigated the potential role of CCL5/CCR5 axis in cetuximab-based treatment in metastatic colorectal cancer (mCRC) patients.

Patients And Methods: Genomic DNA was extracted from 491 samples of two different cohorts with KRAS wild-type mCRC from the FIRE-3 trial: an evaluation cohort of 244 patients receiving cetuximab plus FOLFIRI and a control cohort of 247 patients receiving bevacizumab plus FOLFIRI. Read More

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December 2018

Plio-Pleistocene diversification and biogeographic barriers in southern Australia reflected in the phylogeography of a widespread and common lizard species.

Mol Phylogenet Evol 2018 Dec 13. Epub 2018 Dec 13.

College of Science and Engineering, Flinders University, South Australia; Evolutionary Biology Unit, South Australian Museum.

Palaeoclimatic events and biogeographical processes since the mid-Tertiary have played an important role in shaping the evolution and distribution of Australian fauna. However, their impacts on fauna in southern and arid zone regions of Australia are not well understood. Here we investigate the phylogeography of an Australian scincid lizard, Tiliqua rugosa, across southern Australia using mitochondrial DNA (mtDNA) and 11 nuclear DNA markers (nuDNA), including nine anonymous nuclear loci. Read More

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December 2018

Rheum palmatum extract exerts anti-hepatocellular carcinoma effects by inhibiting signal transducer and activator of transcription 3 signaling.

J Ethnopharmacol 2018 Dec 13. Epub 2018 Dec 13.

School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China; Department of Traditional Chinese Medicine, Nanfang hospital, Southern medical university, Guangzhou 510515, China. Electronic address:

Ethnopharmacological Relevance: Hepatocellular carcinoma (HCC) is among the most common malignancies. Signal transducer and activator of transcription 3 (STAT3), with abnormal expression and constitutive activation, has been reported to promote proliferation, metastasis, survival and angiogenesis of HCC cells. Rheum palmatum (RP), a traditional Chinese medicinal herb, exhibited tumor-suppressing effects in multiple human cancers, but its potential functions in HCC remain unexplored. Read More

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December 2018

Automated and manual hippocampal segmentation techniques: Comparison of results, reproducibility and clinical applicability.

Neuroimage Clin 2018 Oct 14:101574. Epub 2018 Oct 14.

Department of Neurology, Indiana University, Indianapolis, IN, USA; Department of Radiological Sciences, Indiana University, Indianapolis, IN, USA; Department of Medical and Molecular Genetics, Indiana University, Indianapolis, IN, USA. Electronic address:

Background: Imaging techniques used to measure hippocampal atrophy are key to understanding the clinical progression of Alzheimer's disease (AD). Various semi-automated hippocampal segmentation techniques are available and require human expert input to learn how to accurately segment new data. Our goal was to compare 1) the performance of our automated hippocampal segmentation technique relative to manual segmentations, and 2) the performance of our automated technique when provided with a training set from two different raters. Read More

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October 2018

Diabetes mellitus and risk of pancreatic cancer in China: A meta-analysis based on 26 case-control studies.

Prim Care Diabetes 2018 Dec 12. Epub 2018 Dec 12.

Department of General Surgery, Sixth Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030008, China.

Aims: The relationship between diabetes mellitus and pancreatic cancer risk from is uncertain based on the results of existing publications. The current report updated and re-evaluated the possible association between diabetes mellitus and pancreatic cancer risk in China.

Methods: Six databases (PubMed, Embase, Web of Science, the Cochrane Library, the Chinese Biomedical Database, and the Chinese National Knowledge Infrastructure) were used for the literature search up to October 2017. Read More

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December 2018

Modified moist occlusive burn therapy may be a superior therapy for severe thermal burns.

Burns 2018 Dec 12. Epub 2018 Dec 12.

Department of Plastic and Reconstructive Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, PR China. Electronic address:

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December 2018

Patient-Reported Quality of Life as a Predictor of Mortality and Ventricular Tachyarrhythmia's During 7 Years' Follow-Up in Patients With an Implantable Cardioverter Defibrillator (from the MIDAS Study).

Am J Cardiol 2018 Nov 24. Epub 2018 Nov 24.

Department of Psychology, University of Southern Denmark, Odense, Denmark; Department of Cardiology, Odense University Hospital, Odense, Denmark. Electronic address:

Preliminary evidence suggests that poor patient-reported quality of life (QoL) predicts mortality on the short term in patients with an implantable cardioverter defibrillator (ICD). It is unclear if this association persists on the long term. We evaluated whether patient-reported QoL at the time of implantation predicts mortality and ventricular tachyarrhythmias (VTa's) during 7 years' follow-up in patients with an ICD. Read More

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November 2018

IL-17A modulates osteoclast precursors' apoptosis through autophagy-TRAF3 signaling during osteoclastogenesis.

Biochem Biophys Res Commun 2018 Dec 12. Epub 2018 Dec 12.

Academy of Orthopedics, The Third Affiliated Hospital, Southern Medical University, Guangzhou, 510630, China. Electronic address:

Osteoclasts play an important role in bone remodeling. The inflammatory cytokine IL-17A could modulate the RANKL-induced osteoclastogenesis by regulating the autophagic activity. It is well accepted that protective autophagy has an anti-apoptotic effect. Read More

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December 2018

Alginate/chondroitin sulfate based hybrid hydrogel with different molecular weight and its capacity to regulate chondrocytes activity.

Carbohydr Polym 2019 Feb 2;206:229-237. Epub 2018 Nov 2.

Department of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong, PR China; Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, PR China; Shenzhen Key Laboratory of Cell Microenvironment, PR China. Electronic address:

Chondrocytes culture within three-dimensional (3D) hydrogels is an attractive strategy for expanding their potential in various biomedical applications. Molecular weight (MW) of the polymers used for preparing one-component hydrogels for 3D cell culture can affect the activity of chondrocytes. However, whether MW of double network hydrogels affects cell fate remains to be determined. Read More

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February 2019

Pet robot intervention for people with dementia: A systematic review and meta-analysis of randomized controlled trials.

Psychiatry Res 2018 Dec 6;271:516-525. Epub 2018 Dec 6.

School of Nursing, Jilin University, Changchun, China; Department of Pharmacology, college of Basic Medical sciences, Jilin University, Changchun, China. Electronic address:

This study aims to systematically evaluate the efficacy of Pet robot intervention (PRI) for people with dementia. Two waves of electronic searches of the PubMed, EMBASE, Web of Science, Cochrane library, IEEE Digital Library and PsycINFO databases were conducted. In total, eight articles from six randomized controlled trials (RCTs) met the eligibility criteria and were included in this systematic review. Read More

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December 2018

Delignification overmatches hemicellulose removal for improving hydrolysis of wheat straw using the enzyme cocktail from Aspergillus niger.

Bioresour Technol 2018 Dec 10;274:459-467. Epub 2018 Dec 10.

Department of Biology, Lakehead University, Ontario P7B 5E1, Canada. Electronic address:

Based on a general understanding that hemicellulose removal is more efficient than delignification for biomass deconstruction, an Aspergillus niger strain producing high xylanase activity was screened out from seventeen strains by clear halo experiments. Low-cost enzyme cocktail with high xylanase activity was produced from wheat straw medium fermented by the Gyx086 strain. The enzyme cocktail with high xylanase activity could more effectively hydrolyze wheat straw than other biomasses. Read More

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December 2018

Increased postural stiffness during challenging postural tasks in patients with knee osteoarthritis with high pain sensitization.

Clin Biomech (Bristol, Avon) 2018 Dec 8;61:129-135. Epub 2018 Dec 8.

Center for Neuroplasticity and Pain (CNAP), SMI, Aalborg University, Denmark.

Background: Postural stability is affected in knee osteoarthritis patients who present with pain but the link to pain sensitization is unclear.

Methods: Patients with knee osteoarthritis completed the Knee Injury and Osteoarthritis Outcome Score and pressure pain thresholds were assessed bilaterally at the knee, lower leg and forearm prior to standing quietly (1 min) on a force platform in four conditions: Firm surface with open eyes, firm surface with closed eyes, soft surface with open eyes, and soft surface with closed eyes. Pain intensity during standing was assessed via numerical rating scale. Read More

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December 2018
1 Read

Design of a randomized controlled trial on the efficacy of a reproductive health survivorship care plan in young breast cancer survivors.

Contemp Clin Trials 2018 Dec 12. Epub 2018 Dec 12.

Moores Cancer Center, University of California, San Diego, 3855 Health Sciences Dr. La Jolla, CA 92093-090, USA; Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Diego, 9300 Campus Pointe Drive, MC 7433, La Jolla, CA 92037, USA. Electronic address:

Background: Young breast cancer survivors (YBCS) have unmet needs for managing hot flashes, fertility-related concerns, sexual health and contraception.

Purpose: Describe the design and participant characteristics of a randomized controlled trial testing the efficacy of the survivorship care plan on reproductive health (SCP-R) intervention on improving hot flashes, fertility-related concerns, sexual health, and contraception in YBCS.

Methods: SCP-R is a web-based intervention with text message support encompassing evidence- based practices on four reproductive health issues. Read More

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December 2018

The RNA helicase DHX33 is required for cancer cell proliferation in human glioblastoma and confers resistance to PI3K/mTOR inhibition.

Cell Signal 2018 Dec 12. Epub 2018 Dec 12.

Department of Biology, Southern University of Science and Technology, Shenzhen, Guangdong, China. Electronic address:

Human Glioblastoma is one deadly disease; the median survival time is reported to be 13.9 months after treatment. In the present study, we discovered that DHX33 is highly expressed in 84% of all Glioblastoma multiforme (GBM). Read More

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December 2018
2 Reads

Sustained release of recombinant thrombomodulin from cross-linked gelatin/hyaluronic acid hydrogels potentiate wound healing in diabetic mice.

Eur J Pharm Biopharm 2018 Dec 12. Epub 2018 Dec 12.

nstitute of Clinical Pharmacy and Pharmaceutical Sciences, Southern Taiwan University of Science and Technology, Tainan, Taiwan. Electronic address:

Thrombomodulin (TM) is a type-I transmembrane glycoprotein expressed on the surfaces of endothelial cells and epidermal keratinocytes. It is known to regulate blood coagulation, inflammation, and cell-cell adhesion. A recombinant TM, which contains an epidermal growth factor - like domain and serine/threonine-riches domain, has been demonstrated to stimulate cell proliferation and migration of keratinocytes and wound healing. Read More

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December 2018

Different species or genetically divergent populations? Integrative species delimitation of the Primulina hochiensis complex from isolated karst habitats.

Mol Phylogenet Evol 2018 Dec 12. Epub 2018 Dec 12.

Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China. Electronic address:

To consistently and objectively delineate species-level divergence from population subdivision has been a challenge in systematics. This is particularly evident in naturally fragmented and allopatric systems in which small population size often leads to extreme population structuring. Here we evaluated the robustness of the species delimitation methods implemented in BEAST, BPP, and iBPP in the Primulina hochiensis complex comprising four described and one candidate species (five taxa in total) distributed in karst landscapes of southern China. Read More

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December 2018

Oxidative stress in the choroid plexus contributes to blood-cerebrospinal fluid barrier disruption during sepsis development.

Microvasc Res 2018 Dec 12. Epub 2018 Dec 12.

Laboratory of Neurobiology of Inflammatory and Metabolic Processes, Graduate Program in Health Sciences, Health Sciences Unit, University of South Santa Catarina, Tubarão, SC, Brazil. Electronic address:

Background: The choroid plexus (CP), main component of blood-cerebrospinal fluid barrier (BCSFB), protects the brain from peripheral inflammation similar to the blood-brain barrier. Thus, CP is considered a critical target site of oxidative damage, which in sepsis oxidative stress is likely to be a major step in the development of brain damage. Functional alterations in CP may be associated with sepsis-induced brain injury. Read More

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December 2018
1 Read

Radiographic nodal prognostic factors in stage I HPV-related oropharyngeal squamous cell carcinoma.

Head Neck 2018 Dec 15. Epub 2018 Dec 15.

Department of Radiation Oncology, Southern California Permanente Medical Group, Los Angeles, California.

Background: The updated AJCC Cancer Staging Manual groups all p16-positive oropharyngeal squamous cell carcinoma (OPSCC) with unilateral nodal involvement within 6 cm into the new clinical N1 classification, consolidating a heterogeneous group of disease with varying radiographic findings.

Methods: A central radiological review was conducted identifying 233 patients with stage I node-positive (cT1-2N1) disease who underwent definitive concurrent chemoradiation. Factors evaluated included lymph node size, low-neck lymphadenopathy, retropharyngeal lymphadenopathy, overt radiographic extracapsular extension, and matted lymphadenopathy. Read More

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December 2018
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Parents' experiences of donation to their child before kidney transplantation: A qualitative study.

J Clin Nurs 2018 Dec 14. Epub 2018 Dec 14.

Department of Clinical Institute, University of Southern, Denmark.

Aim And Objectives: To explore Parents' experiences of donation to their child before kidney transplantation.

Background: Transplantation is the treatment of choice for pediatric patients with end-stage renal disease. Living donor kidney transplantation has shown a higher long-term transplant survival compared to deceased donor transplantation and entails a more controllable process, with shorter waiting time. Read More

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December 2018

Antiemetic use of olanzapine in patients with advanced cancer: results from an open-label multicenter study.

Support Care Cancer 2018 Dec 14. Epub 2018 Dec 14.

Department of Clinical Oncology, Zealand University Hospital, Roskilde, Denmark.

Introduction: The antipsychotic drug olanzapine is effective against chemotherapy-induced nausea and targets multiple receptors known to be involved in the emetic reflex arch. The drug has a mean half-life of 30 h, which allows for a single daily administration and is therefore of interest in patients with advanced cancer suffering from nausea.

Objectives: To investigate the antiemetic effect and tolerability of olanzapine in patients with advanced cancer not receiving chemotherapy or irradiation. Read More

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December 2018

In vitro-to-in vivo extrapolation (IVIVE) by PBTK modeling for animal-free risk assessment approaches of potential endocrine-disrupting compounds.

Arch Toxicol 2018 Dec 14. Epub 2018 Dec 14.

BASF SE, Experimental Toxicology and Ecology, Carl Bosch Straße 38, 67056, Ludwigshafen, Germany.

While in vitro testing is used to identify hazards of chemicals, nominal in vitro assay concentrations may misrepresent potential in vivo effects and do not provide dose-response data which can be used for a risk assessment. We used reverse dosimetry to compare in vitro effect concentrations-to-in vivo doses causing toxic effects related to endocrine disruption. Ten compounds (acetaminophen, bisphenol A, caffeine, 17α-ethinylestradiol, fenarimol, flutamide, genistein, ketoconazole, methyltestosterone, and trenbolone) have been tested in the yeast estrogen screening (YES) or yeast androgen-screening (YAS) assays for estrogen and androgen receptor binding, as well as the H295R assay (OECD test guideline no. Read More

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December 2018

Reasons to stop drinking alcohol among patients with rheumatoid arthritis in Sweden: a mixed-methods study.

BMJ Open 2018 Dec 14;8(12):e024367. Epub 2018 Dec 14.

Spenshult Research and Development Center, Spenshult, Halmstad, Sweden.

Objectives: The aims were to identify patients with rheumatoid arthritis (RA) who had stopped drinking alcohol and compare them with patients drinking alcohol, and to explore reasons for stopping drinking alcohol.

Design: A sequential explanatory mixed methods design was used.

Setting: Six rheumatology clinics in Southern Sweden Better Anti-Rheumatic FarmacOTherapy cohort. Read More

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December 2018

Disability and morbidity among older patients in the emergency department: a Danish population-based cohort study.

BMJ Open 2018 Dec 14;8(12):e023803. Epub 2018 Dec 14.

Department of Geriatric Medicine, Odense University Hospital, Odense, Denmark.

Objectives: The objective was to describe the prevalence of geriatric conditions among older medical patients in the emergency department (ED) and the association with admission, mortality, reattendance and loss of independency.

Design: Population-based prospective cohort study.

Setting: ED of a large university hospital. Read More

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December 2018

Is the decline in neonatal mortality in northern Ghana, 1996-2012, associated with the decline in the age of BCG vaccination? An ecological study.

BMJ Open 2018 Dec 14;8(12):e023752. Epub 2018 Dec 14.

Navrongo Health Research Centre, Navrongo, Ghana.

Objective: To examine the association between early Bacille Calmette-Guerin (BCG) vaccination and neonatal mortality in northern Ghana.

Methods: This ecological study used vaccination and mortality data from the Navrongo Health and Demographic Surveillance System. First, we assessed and compared changes in neonatal mortality rates (NMRs) and median BCG vaccination age from 1996 to 2012. Read More

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December 2018

ICF Generic Set as new standard for the system wide assessment of functioning in China: a multicentre prospective study on metric properties and responsiveness applying item response theory.

BMJ Open 2018 Dec 14;8(12):e021696. Epub 2018 Dec 14.

Swiss Paraplegic Research, Nottwil, Switzerland.

Objectives: To examine metric properties and responsiveness of the International Classification of Functioning, Disability and Health (ICF) Generic Set when used in routine clinical practice to assess functioning.

Design: Prospective multicentre study.

Setting: 50 hospitals from 20 provinces of Mainland China. Read More

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December 2018
2 Reads

Stent-screw-assisted internal fixation: the SAIF technique to augment severe osteoporotic and neoplastic vertebral body fractures.

J Neurointerv Surg 2018 Dec 14. Epub 2018 Dec 14.

Department of Neuroradiology, Papa Giovanni XXIII Hospital, Bergamo, Italy.

Objectives: To describe a new technique to obtain minimally invasive but efficient vertebral body (VB) reconstruction, augmentation, and stabilization in severe osteoporotic and neoplastic fractures, combining two pre-existing procedures. The implant of vertebral body stents (VBS) is followed by insertion of percutaneous, fenestrated, cement-augmented pedicular screws that act as anchors to the posterior elements for the cement/stent complex. The screws reduce the risk of stent mobilization in a non-intact VB cortical shell and bridge middle column and pedicular fractures. Read More

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December 2018

Postdischarge Mortality Prediction in Sub-Saharan Africa.

Pediatrics 2018 Dec 14. Epub 2018 Dec 14.

Centro de Investigação em Saúde de Manhiça, Maputo, Mozambique;

Background: Although the burden of postdischarge mortality (PDM) in low-income settings appears to be significant, no clear recommendations have been proposed in relation to follow-up care after hospitalization. We aimed to determine the burden of pediatric PDM and develop predictive models to identify children who are at risk for dying after discharge.

Methods: Deaths after hospital discharge among children aged <15 years in the last 17 years were reviewed in an area under demographic and morbidity surveillance in Southern Mozambique. Read More

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December 2018

Disparities in Inter-hospital Helicopter Transportation for Hispanics by Geographic Region: A Threat to Fairness in the Era of Thrombectomy.

J Stroke Cerebrovasc Dis 2018 Dec 11. Epub 2018 Dec 11.

Department of Neurology, University of Iowa, Iowa City, Iowa; Department of Neurosurgery, University of Iowa, Iowa City, Iowa; Department of Epidemiology, University of Iowa, Iowa City, Iowa. Electronic address:

Background And Purpose: Mechanical thrombectomy (MT) is a time-dependent therapy that is only available at a limited number of hospitals. As such, patients that live at a considerable distance of those specialized centers often require rapid interhospital emergent evacuation with Helicopter Emergency Medical Services (HEMS) to be considered for MT. It is not known whether the use of HEMS is equitable across different groups of patients. Read More

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December 2018
1 Read

Focused Resident Education and Engagement in Quality Improvement Enhances Documentation, Shortens Hospital Length of Stay, and Creates a Culture of Continuous Improvement.

J Surg Educ 2018 Dec 12. Epub 2018 Dec 12.

Comprehensive Aortic Center, Cardiovascular Thoracic Institute, Keck Medical Center of University of Southern California, Los Angeles, California. Electronic address:

Purpose: System-based practice with an emphasis on quality improvement (QI) is a recent initiative for the American College of Surgeons and a core-competency for surgical trainees. Few surgical training programs have a curriculum for hospital-based QI.

Methods: Our vascular surgery service implemented several QI initiatives focused on decreasing length of stay (LOS) by targeting resident education and engagement. Read More

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December 2018

HCMV jogs the 'memory' of NK cells in HBV.

J Hepatol 2018 Dec 11. Epub 2018 Dec 11.

Department of Medicine, Keck School of Medicine, Research Center for Liver Diseases, University of Southern California, Los Angeles, CA, USA.

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December 2018

Granisetron protects polymicrobial sepsis-induced acute lung injury in mice.

Biochem Biophys Res Commun 2018 Dec 11. Epub 2018 Dec 11.

Department of Pathophysiology, Guangdong Provincial Key Laboratory of Proteomics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China; State Key Laboratory of Organ Failure Research, Southern Medical University, Guangzhou, China. Electronic address:

Sepsis is a serious condition with a high mortality rate worldwide. Granisetron is an anti-nausea drug for patients undergoing chemotherapy. Here we aimed to identify the novel effect of granisetron on sepsis-induced acute lung injury (ALI). Read More

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December 2018
1 Read

G protein-coupled receptors in arthropod vectors: omics and pharmacological approaches to elucidate ligand-receptor interactions and novel organismal functions.

Curr Opin Insect Sci 2018 Oct 26;29:12-20. Epub 2018 May 26.

Department of Electrical and Computer Engineering, TAMU, College Station, TX 77843-3128, United States.

Regulation of many physiological processes in animals, certainly those controlled by neuropeptide hormones, involves G protein-coupled receptors (GPCRs). Our work focusing on endocrine regulation of diuresis and water balance in mosquitoes and ticks started in 1997 with the kinin receptor, at the dawn of the omics era. After the genomic revolution, we began work on the endocrinology of reproduction in the red imported fire ant. Read More

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October 2018

Identification of Brucella abortus biovar 4 of bovine origin in Colombia.

Rev Argent Microbiol 2018 Dec 11. Epub 2018 Dec 11.

Corporación Colombiana de Investigación Agropecuaria AGROSAVIA, Centro de investigación Tibaitatá, Km 14 vía Mosquera-Bogotá, Mosquera, Colombia. Electronic address:

The objective of this study was to identify twelve Brucella abortus isolates of bovine origin from the department of Nariño in Colombia up to the biovar level. These isolates are included in the collection of the Germplasm Bank of Microorganisms of Animal Health Interest - Bacteria and Virus (BGSA-BV). The identification was carried out through conventional methods such as macro and microscopic morphological descriptions, enzymatic activity, biochemical profile, substrate use and sensitivity to dyes. Read More

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December 2018

Social nutrition: an emerging field in insect science.

Curr Opin Insect Sci 2018 Aug 18;28:73-80. Epub 2018 May 18.

School of Agriculture, Food and Wine, The University of Adelaide, Waite Campus, Southern Australia 5005, Australia.

Nutrition is thought to be a major driver of social evolution, yet empirical support for this hypothesis is scarce. Here we illustrate how conceptual advances in nutritional ecology illuminate some of the mechanisms by which nutrition mediates social interactions in insects. We focus on experiments and models of nutritional geometry and argue that they provide a powerful means for comparing nutritional phenomena across species exhibiting various social ecologies. Read More

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August 2018
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Post-Harvest Contamination with Mycotoxins in the Context of the Geographic and Agroclimatic Conditions in Romania.

Toxins (Basel) 2018 Dec 13;10(12). Epub 2018 Dec 13.

National Research & Development Institute for Food Bioresources-IBA Bucharest, 5 Baneasa Ancuta Street, 2nd district, Bucharest 020323, Romania.

This study aimed to assess post-harvest contamination with mycotoxins in the context of the geographic and agroclimatic conditions in Romania in 2012⁻2015, a period that was characterized by extreme meteorological events and the effects of climate change. The samples were randomly sampled from five agricultural regions of Romania and analyzed for mycotoxins by enzyme-linked immunosorbent assay. An SPSS analysis was done to explore correlations between mycotoxins (deoxynivalenol-DON, aflatoxins-AF, ochratoxin A-OTA, zearalenone-ZEA), product types (raw cereal, processed cereal, cereal-based food), geographic coordinates (latitude, longitude, agricultural region), and agroclimatic factors (air temperature, precipitation, soil moisture reserve, aridity index, soil type). Read More

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December 2018

The Influence of Antidepressants on the Disease Course Among Patients With Crohn's Disease and Ulcerative Colitis-A Danish Nationwide Register-Based Cohort Study.

Inflamm Bowel Dis 2018 Dec 14. Epub 2018 Dec 14.

National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.

Background: Psychiatric comorbidity might modify the disease course adversely in patients with inflammatory bowel disease (IBD). Treatment options include antidepressants, which, apart from improving mood, have anti-inflammatory properties that might modify the disease course. This nationwide study aimed to examine the influence of antidepressants on the disease course among patients with ulcerative colitis (UC) and Crohn's disease (CD). Read More

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December 2018
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Can mHealth improve timeliness and quality of health data collected and used by health extension workers in rural Southern Ethiopia?

J Public Health (Oxf) 2018 Dec;40(suppl_2):ii74-ii86

REACH Ethiopia, Hawassa, Ethiopia.

Background: Health extension workers (HEWs) are the key cadre within the Ethiopian Health Extension Programme extending health care to rural communities. National policy guidance supports the use of mHealth to improve data quality and use. We report on a mobile Health Management Information system (HMIS) with HEWs and assess its impact on data use, community health service provision and HEWs' experiences. Read More

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December 2018
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'The phone is my boss and my helper' - A gender analysis of an mHealth intervention with Health Extension Workers in Southern Ethiopia.

J Public Health (Oxf) 2018 Dec;40(suppl_2):ii16-ii31

Department of International Public Health, Liverpool School of Tropical Medicine, Pembroke Place, L3 5QA, UK.

Background: There is considerable optimism in mHealth's potential to overcome health system deficiencies, yet gender inequalities can weaken attempts to scale-up mHealth initiatives. We report on the gendered experiences of an mHealth intervention, in Southern Ethiopia, realised by the all-female cadre of Health Extension Workers (HEWs).

Methodology: Following the introduction of the mHealth intervention, in-depth interviews (n = 19) and focus group discussions (n = 8) with HEWs, supervisors and community leaders were undertaken to understand whether technology acted as an empowering tool for HEWs. Read More

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December 2018
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Measuring mental well-being in Denmark: Validation of the original and short version of the Warwick-Edinburgh mental well-being scale (WEMWBS and SWEMWBS) and cross-cultural comparison across four European settings.

Psychiatry Res 2018 Dec 5;271:502-509. Epub 2018 Dec 5.

The Danish National Institute of Public Health, University of Southern Denmark, Studiestraede 6, 1455 Copenhagen, Denmark. Electronic address:

This study examined the psychometric properties of the Danish WEMWBS and its short version (SWEMWBS) in a Danish population sample, and compared scores in Denmark with scores representative of three other European settings. A total of 3,508 Danish men and women aged 16-95 filled out an electronic survey. Face validity was examined by cognitive interviews. Read More

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December 2018