684,486 results match your criteria South Dakota medicine : the journal of the South Dakota State Medical Association[Journal]


Whole-genome analysis of the colonization-resistant bacterium Phytobacter sp. SCO41 isolated from Bacillus nematocida B16-fed adult Caenorhabditis elegans.

Mol Biol Rep 2019 Mar 16. Epub 2019 Mar 16.

Department of Life Science and Biotechnology, Nanyang Normal University, Nanyang, 473000, People's Republic of China.

Colonization resistance is an important attribute for bacterial interactions with hosts, but the mechanism is still not completely clear. In this study, we found that Phytobacter sp. SCO41 can effectively inhibit the in vivo colonization of Bacillus nematocida B16 in Caenorhabditis elegans, and we revealed the colonization resistance mechanism. Read More

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http://link.springer.com/10.1007/s11033-018-04574-w
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http://dx.doi.org/10.1007/s11033-018-04574-wDOI Listing
March 2019
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Are bottom-up approaches good for promoting social-ecological fit in urban landscapes?

Ambio 2019 Mar 16. Epub 2019 Mar 16.

Stockholm Resilience Centre, Stockholm University, Kräftriket 2B, 10691, Stockholm, Sweden.

Bottom-up approaches are often presented as a remedy to environmental governance problems caused by poorly aligned social institutions and fragmented ecosystems. However, there is a lack of empirical evidence demonstrating how such social-ecological fit might emerge and help achieve desirable outcomes. This paper combines quantitative social-ecological network analysis with interviews to investigate whether bottom-up approaches in lake governance improve the fit. Read More

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http://dx.doi.org/10.1007/s13280-019-01163-4DOI Listing

Status and trends of terrestrial arthropod abundance and diversity in the North Atlantic region of the Arctic.

Ambio 2019 Mar 16. Epub 2019 Mar 16.

Arctic Research Centre, Aarhus University, Ny Munkegade 114, bldg. 1540, 8000, Aarhus C, Denmark.

The Circumpolar Biodiversity Monitoring Programme (CBMP) provides an opportunity to improve our knowledge of Arctic arthropod diversity, but initial baseline studies are required to summarise the status and trends of planned target groups of species known as Focal Ecosystem Components (FECs). We begin this process by collating available data for a relatively well-studied region in the Arctic, the North Atlantic region, summarising the diversity of key terrestrial arthropod FECs, and compiling trends for some representative species. We found the FEC classification system to be challenging to implement, but identified some key groups to target in the initial phases of the programme. Read More

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http://dx.doi.org/10.1007/s13280-019-01162-5DOI Listing

Human papillomavirus risk perceptions and relationship status: a barrier to HPV vaccination?

J Behav Med 2019 Mar 16. Epub 2019 Mar 16.

Community and Family Health Concentration, College of Public Health, University of South Florida, 13201 Bruce B. Downs Blvd, Tampa, FL, 32612, USA.

The purpose of this study was to assess the association between relationship status and perceived risk for human papillomavirus (HPV) among young adults. College adults, aged 18-26 years, completed an online survey from November 2016-April 2017 (n = 385). The survey assessed HPV vaccination status, perceived HPV risk, and current relationship status. Read More

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http://dx.doi.org/10.1007/s10865-019-00025-4DOI Listing

Geochemistry of uranium and thorium in phosphate deposits at the Syrian coastal area (Al-Haffah and Al-Qaradaha) and their environmental impacts.

Environ Geochem Health 2019 Mar 16. Epub 2019 Mar 16.

Department of Protection and Safety, Atomic Energy Commission of Syria, P.O. Box 6091, Damascus, Syria.

The aim of this research was to study the geochemistry of uranium and thorium in phosphate deposits in the upper Cretaceous phosphate deposits in the Syrian coastal area. The study covered three sites, namely Ain Al-Tenah, Ain Laylon, and Al-Mhalbeh. Petrographical study showed that phosphate deposits are of nodular type with micrit to microspaite cement, containing siliceous bone residues, and green grains of glauconite, which are increasing in abundance and volume in the south toward Al-Mhalbeh, reflecting the formation of phosphate in a shallow marine environment. Read More

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http://dx.doi.org/10.1007/s10653-018-0221-xDOI Listing

Reliability and validity of self-reported questionnaires to measure pain and disability in adults with neck pain and its associated disorders: part 3-a systematic review from the CADRE Collaboration.

Eur Spine J 2019 Mar 16. Epub 2019 Mar 16.

UOIT-CMCC Centre for Disability Prevention and Rehabilitation, University of Ontario Institute of Technology (UOIT), 2000 Simcoe St. N., Oshawa, ON, L1H 7K4, Canada.

Purpose: To determine the reliability and validity of self-reported questionnaires to measure pain and disability in adults with grades I-IV neck pain and its associated disorders (NAD).

Methods: We updated the systematic review of the 2000-2010 Bone and Joint Decade Task Force on Neck Pain and its Associated Disorders and systematically searched databases from 2005 to 2017. Independent reviewers screened and critically appraised studies using standardized tools. Read More

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http://dx.doi.org/10.1007/s00586-019-05949-8DOI Listing

Agricultural land-use history does not reduce woodland understory herb establishment.

Oecologia 2019 Mar 16. Epub 2019 Mar 16.

Department of Plant Biology, Michigan State University, East Lansing, USA.

Agricultural land use is a leading cause of habitat degradation, leaving a legacy of ecological impacts long after agriculture has ceased. Yet the mechanisms for legacy effects, such as altered plant community composition, are not well understood. In particular, whether plant community recovery is limited by an inability of populations to establish within post-agricultural areas, owing to altered environmental conditions within these areas, remains poorly known. Read More

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http://dx.doi.org/10.1007/s00442-019-04348-6DOI Listing

Heterogeneity in costs and prognosis for acute ischemic stroke treatment by comorbidities.

J Neurol 2019 Mar 16. Epub 2019 Mar 16.

Department of Neurology, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.

Objective: Comorbidities are prevalent among stroke patients. The current study assesses the variations in cost and stroke prognosis by concurrent comorbidities in patients with acute ischemic stroke.

Methods: The Charlson comorbidity index was used as the composite comorbidity level (0 none, 1 mild, 2 moderate, and ≥ 3 severe). Read More

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http://dx.doi.org/10.1007/s00415-019-09278-0DOI Listing

The effects of different sampling techniques on peripheral post mortem tryptase levels: a recommended sampling method.

Int J Legal Med 2019 Mar 16. Epub 2019 Mar 16.

Department of Forensic Pathology, LabPLUS, Auckland City Hospital, Auckland, 1148, New Zealand.

Different sampling techniques can impact on post mortem tryptase levels. A previous study demonstrated significantly lower femoral post mortem total tryptase levels in samples collected via transcutaneous aspiration compared with directly sampling during internal examination. However, an outlier with high tryptase level was noted in one transcutaneous aspiration sample. Read More

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http://dx.doi.org/10.1007/s00414-019-02038-9DOI Listing

The effect of combination therapy on critical-size bone defects using non-activated platelet-rich plasma and adipose-derived stem cells.

Childs Nerv Syst 2019 Mar 16. Epub 2019 Mar 16.

Department of Plastic and Reconstructive Surgery, Institute for Human Tissue Restoration, Yonsei University Health System, Gangnam Severance Hospital, 211 Eonjoo-ro, Gangnam-gu, Seoul, 135-720, South Korea.

Purpose: Non-activated platelet-rich plasma (nPRP) slowly releases growth factors that induce bone regeneration. Adipose tissue-derived stem cells (ASCs) are also known to induce osteoblast differentiation. In this study, we investigated the combined effect of nPRP and ASC treatment compared with single therapy on bone regeneration. Read More

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http://dx.doi.org/10.1007/s00381-019-04109-zDOI Listing

Levels of Polycyclic Aromatic Hydrocarbons in the Water and Sediment of Buffalo River Estuary, South Africa and Their Health Risk Assessment.

Arch Environ Contam Toxicol 2019 Mar 16. Epub 2019 Mar 16.

SAMRC Microbial Water Quality Monitoring Centre, University of Fort Hare, Alice, 5700, South Africa.

The incidence and spatial distribution of polycyclic aromatic hydrocarbons (PAHs) in the Buffalo River Estuary in the Eastern Cape Province of South Africa were assessed in this study. A total of 60 surface water and 19 sediment samples were collected from 5 sites of the estuary over a period of 6 months (December 2015 to May 2016). Extraction of PAHs from the water and sediment samples was achieved by using liquid-liquid and soxhlet extraction methods respectively, followed by column clean up with silica gel and quantification by gas chromatography-flame ionization detection. Read More

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http://dx.doi.org/10.1007/s00244-019-00617-wDOI Listing

Gender-related morphological differences in sulcus angle and condylar height for the femoral trochlea using magnetic resonance imaging.

Knee Surg Sports Traumatol Arthrosc 2019 Mar 16. Epub 2019 Mar 16.

Department of Mechanical Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.

Purpose: This study aimed to elucidate the primary differences in trochlear morphology between men and women utilizing three-dimensional magnetic resonance image reconstruction of the femoral trochlea.

Methods: Differences in anthropometric femoral trochlea data of 975 patients (825 women, 150 men) were evaluated. The following morphological parameters were measured at three flexion angles (15°, 30°, and 45°) of the femoral trochlea: the sulcus angle, condylar height, and the trochlear groove orientation and mediolateral groove position. Read More

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http://dx.doi.org/10.1007/s00167-019-05423-4DOI Listing

Toffee Men, Travelling Drapers and Black-Market Perfumers-South Asian Networks of Petty Trade in Early Twentieth Century Britain.

Authors:
David Holland

20 Century Br Hist 2019 Mar 15. Epub 2019 Mar 15.

University of Sheffield.

Selling small wares, novelties, and affordable luxuries manufactured from artificial silk, the South Asian door-to-door pedlar or 'travelling draper', and his compatriot the 'Indian toffee man', were once fairly commonplace figures in British working-class life and the object of fond childhood recollections for many. Unfortunately, they have now largely drifted from popular memory, having left little trace in the historical record. However, this article's reconstruction of their lives offers a new perspective on the pivotal role inter-racial social networks played in pioneering South Asian immigration, settlement, and trade in Britain. Read More

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http://dx.doi.org/10.1093/tcbh/hwz003DOI Listing

Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients.

Ann Rheum Dis 2019 Mar 16. Epub 2019 Mar 16.

Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute, Barts & The London School of Medicine & Dentistry, Queen Mary University of London, London, UK

Objectives: To unravel the hierarchy of cellular/molecular pathways in the disease tissue of early, treatment-naïve rheumatoid arthritis (RA) patients and determine their relationship with clinical phenotypes and treatment response/outcomes longitudinally.

Methods: 144 consecutive treatment-naïve early RA patients (<12 months symptoms duration) underwent ultrasound-guided synovial biopsy before and 6 months after disease-modifying antirheumatic drug (DMARD) initiation. Synovial biopsies were analysed for cellular (immunohistology) and molecular (NanoString) characteristics and results compared with clinical and imaging outcomes. Read More

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http://dx.doi.org/10.1136/annrheumdis-2018-214539DOI Listing

Back Pain and Radiculopathy from Non-Steroidal Anti-Inflammatory Drug-induced Dorsal Epidural Haematoma.

BMJ Case Rep 2019 Mar 15;12(3). Epub 2019 Mar 15.

Division of Neurosurgery, Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina, USA.

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http://dx.doi.org/10.1136/bcr-2018-229015DOI Listing

Cross-sectional analysis of veterinary student coping strategies and stigma in seeking psychological help.

Vet Rec 2019 Mar 16. Epub 2019 Mar 16.

School of Animal and Veterinary Sciences, University of Adelaide, Roseworthy, South Australia, Australia.

Veterinary education can result in high levels of academic stressors for students. Students are also susceptible to non-academic stressors, including relationship issues and financial concerns. These can all result in mental ill health, which may impair the student's ability to complete their studies and go on to a successful professional career. Read More

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http://dx.doi.org/10.1136/vr.105042DOI Listing

Current states and challenges of salt-affected soil remediation by cyanobacteria.

Sci Total Environ 2019 Mar 8;669:258-272. Epub 2019 Mar 8.

School of Pharmaceutical Science, Nanjing Tech University, No. 30 Puzhu South Road, Nanjing 211816, People's Republic of China; Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), People's Republic of China; State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, No. 5 Xinmofan Road, Nanjing 210009, People's Republic of China.

Natural and human activities lead to soil degradation and soil salinization. The decrease of farmlands threatens food security. There are approximately 1 billion ha salt-affected soils all over of world, which can be made available resources after chemical, physical and biological remediation. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.03.104DOI Listing

Is 2030 too soon for Africa to achieve the water and sanitation sustainable development goal?

Sci Total Environ 2019 Mar 10;669:129-139. Epub 2019 Mar 10.

Department of Economics, Unisa, P.O. Box 392, Unisa 0003, South Africa. Electronic address:

Water-Sanitation-Hygiene (WASH) remains vital for the 2030 Agenda for Sustainable Development, yet many countries have not localised the 17 Sustainable Development Goals (SDGs), including SDG 6, which focuses on ensuring the availability and sustainable management of water and sanitation for all. Even in leading African economies such as South Africa, many communities still use the bucket system for sanitation. Using a Composite Index drawn from three indicators whose data were available for 53 of the 54 African countries, it emerged that these states are at various stages of fulfilling the targets set out in SDG 6. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.03.109DOI Listing

Treatment of Locally Advanced Nasopharyngeal Carcinoma by Helical Tomotherapy: An Observational, Prospective Analysis.

Transl Oncol 2019 Mar 14;12(5):757-763. Epub 2019 Mar 14.

Department of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX.

Nasopharyngeal carcinoma (NPC) is endemic in southern China. Due to the unique anatomical and biological properties of NPCs, radiotherapy or combined modality based on radiotherapy is an effective treatment option. Helical tomotherapy (HT) is an emerging intensity modulated radiotherapy technology. Read More

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http://dx.doi.org/10.1016/j.tranon.2019.02.011DOI Listing

Arterial Spin Labeling for Glioma Grade Discrimination: Correlations with IDH1 Genotype and 1p/19q Status.

Transl Oncol 2019 Mar 14;12(5):749-756. Epub 2019 Mar 14.

Department of Radiology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, 651 Dongfeng East Road, Guangzhou 510060, China. Electronic address:

Since accurate grading of gliomas has important clinical value, the aim of this study is to evaluate the diagnostic efficacy of perfusion values derived from arterial spin labeling (ASL) to grade gliomas. In addition, the correlation between perfusion and isocitrate dehydrogenase 1 (IDH1) genotypes and chromosome arms 1p and 19q (1p/19q) status of gliomas was assessed. A total of 52 cases of supratentorial gliomas in adults who received ASL imaging were enrolled in this retrospective study. Read More

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http://dx.doi.org/10.1016/j.tranon.2019.02.013DOI Listing

Alcohol and parenthood: An integrative analysis of the effects of transition to parenthood in three Australasian cohorts.

Drug Alcohol Depend 2019 Feb 13;197:326-334. Epub 2019 Feb 13.

Centre for Adolescent Health, Murdoch Children's Research Institute, Melbourne, VIC, Australia; Department of Paediatrics, University of Melbourne, Melbourne, VIC, Australia.

Aims: To determine the extent to which the transition to parenthood protects against heavy and problematic alcohol consumption in young men and women.

Design: Integrated participant-level data analysis from three population-based prospective Australasian cohort studies.

Setting: General community; participants from the Australian Temperament Study, the Christchurch Health and Development Study, and the Victorian Adolescent Health Cohort Study. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.02.004DOI Listing
February 2019

All-cause mortality and long-term exposure to low level air pollution in the '45 and up study' cohort, Sydney, Australia, 2006-2015.

Environ Int 2019 Mar 14;126:762-770. Epub 2019 Mar 14.

Centre for Air Pollution, Energy and Health Research, Australia; The University of Sydney, University Centre for Rural Health, School of Public Health, Sydney, Australia.

Background: Epidemiological studies show that long-term exposure to ambient air pollution reduces life expectancy. Most studies have been in environments with relatively high concentrations such as North America, Europe and Asia. Associations at the lower end of the concentration-response function are not well defined. Read More

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http://dx.doi.org/10.1016/j.envint.2019.02.044DOI Listing

Household dampness-related exposures in relation to childhood asthma and rhinitis in China: A multicentre observational study.

Environ Int 2019 Mar 14;126:735-746. Epub 2019 Mar 14.

School of Environmental Science and Engineering, Tianjin University, Tianjin, China.

During 2010-2012, we conducted an observational study on household environment and health outcomes among 40,010 preschool children from seven cities of China. Here we examined associations of six dampness-related indicators (visible mold spots, visible damp stains, damp clothing and/or bedding, water damage, condensation on windowpane, moldy odor) in the current residence and three dampness-related indicators (visible mold spots, condensation on windowpane, moldy odor) in the early residence with childhood asthma and rhinitis. In the multi-level logistic regression analyses, visible mold spots and visible damp stains in the current residence were significantly associated with the increased odds of doctor-diagnosed asthma and allergic rhinitis during lifetime-ever (adjusted odd ratios (AORs) range: 1. Read More

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http://dx.doi.org/10.1016/j.envint.2019.03.013DOI Listing

Community greenness, blood pressure, and hypertension in urban dwellers: The 33 Communities Chinese Health Study.

Environ Int 2019 Mar 14;126:727-734. Epub 2019 Mar 14.

Guangzhou Key Laboratory of Environmental Pollution and Health Risk Assessment, Guangdong Provincial Engineering Technology Research Center of Environmental and Health risk Assessment, Department of Occupational and Environmental Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China. Electronic address:

Background: Living in greener areas has many health benefits, but evidence concerning the effects on blood pressure remains mixed. We sought to assess associations between community greenness and both blood pressure and hypertension in Chinese urban dwellers, and whether the associations were mediated by air pollution, body mass index, and physical activity.

Methods: We analyzed data from 24,845 adults participating in the 33 Communities Chinese Health Study, which was conducted in Northeastern China during 2009. Read More

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http://dx.doi.org/10.1016/j.envint.2019.02.068DOI Listing

Multi-omics response of Pannonibacter phragmitetus BB to hexavalent chromium.

Environ Pollut 2019 Mar 6;249:63-73. Epub 2019 Mar 6.

Institute of Environmental Science and Engineering, School of Metallurgy and Environment, Central South University, 410083, Changsha, China; National Engineering Research Center for Heavy Metals Pollution Control and Treatment, 410083, Changsha, China. Electronic address:

The release of hexavalent chromium [Cr(VI)] into water bodies poses a major threat to the environment and human health. However, studies of the biological response to Cr(VI) are limited. In this study, a toxic bacterial mechanism of Cr(VI) was investigated using Pannonibacter phragmitetus BB (hereafter BB), which was isolated from chromate slag. Read More

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http://dx.doi.org/10.1016/j.envpol.2019.03.005DOI Listing

Improving moisture stability of SrLiAlN:Eu through phosphor-in-glass approach to realize its application in plant growing LED device.

J Colloid Interface Sci 2019 Mar 11;545:195-199. Epub 2019 Mar 11.

Guangdong Provincial Engineering Technology Research Center for Optical Agriculture, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China. Electronic address:

Herein, we present a simple strategy to enhance the stability of water-sensitive SrLiAlN:Eu phosphor through embedding the phosphor particles into low-melting Sn-P-F-O glass using phosphor-in-glass (PiG) approach. After being immersed in water for 96 h, the emission intensity of the SrLiAlN:Eu-PiG sample was maintained at 80% of its pristine intensity, indicating the moisture-resistance property of SrLiAlN:Eu was significantly enhanced. Employing the narrow-band red-emitting SrLiAlN:Eu-PiG sample and a blue COB (chip-on-board), a plant growing LED device was fabricated. Read More

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http://dx.doi.org/10.1016/j.jcis.2019.03.032DOI Listing

Plant cell surface immune receptor complex signaling.

Curr Opin Plant Biol 2019 Mar 14;50:18-28. Epub 2019 Mar 14.

Department of Plant Biochemistry, Centre for Plant Molecular Biology (ZMBP), Eberhard Karls University Tübingen, Auf der Morgenstelle 32, D-72076 Tübingen, Germany. Electronic address:

Plant plasma membrane pattern recognition receptors are key to microbe sensing and activation of immunity to microbial invasion. Plants employ several types of such receptors that differ mainly in the structure of their ectodomains and the presence or absence of a cytoplasmic protein kinase domain. Plant immune receptors do not function as single entities, but form larger complexes which undergo compositional changes in a ligand-dependent manner. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13695266183017
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http://dx.doi.org/10.1016/j.pbi.2019.02.001DOI Listing
March 2019
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Evaluation of Postoperative Spinal Epidural Eematoma after Bi portal Endoscopic Spine Surgery (BESS) for Single Level Lumbar Spinal Stenosis : Clinical and Magnetic Resonance Image Study.

World Neurosurg 2019 Mar 13. Epub 2019 Mar 13.

Department of Orthopaedic Surgery, Chungnam National University School of Medicine, Daejeon, Republic of Korea.

Background: Symptomatic postoperative spinal epidural hematoma is a serious complication that may occur after lumbar spine surgery. Authors analyzed epidural hematoma using postoperative MRI after biportal endoscopic spinal surgery and the impact of which to the clinical outcome.

Methods: The subject of this study were 158 patients who underwent single-level decompression using the biportal endoscopic spinal surgery technique from 2015 to 2017. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.02.150DOI Listing

Spotting inferior petrosal sinus for embolizing cavernous dural arteriovenous fistula with the help of preoperative computed tomography angiography.

World Neurosurg 2019 Mar 13. Epub 2019 Mar 13.

Department of Neurosurgery, Xiangya Hospital, Central South University. Electronic address:

Background: Inferior petrosal sinus (IPS) is commonly adopted as a route in embolizing cavernous dural arteriovenous fistula (cDAVF). According to previous anatomical studies, more than 90% of people have IPS. Since exact confluence position of IPS with an internal jugular vein (IJV) is hard to be obtained from preoperative digital subtraction angiography (DSA), catheterizing into IPS in endovascular treatment sometimes become very difficult, so this route has not been as widely used as the anatomical statement. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.03.047DOI Listing

Full endoscopic discectomy, debridement, and drainage for high-risk patients with spondylodiscitis.

World Neurosurg 2019 Mar 13. Epub 2019 Mar 13.

Division of Neurosurgery, Department of Surgery, Changhua Christian Hospital, Changhua, Taiwan; School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; College of Nursing and Health Sciences, Dayeh University, Taiwan. Electronic address:

Objective: To evaluate the efficacy and clinical results of full endoscopic debridement and drainage (FEDD) for high-risk patients with spondylodiscitis.

Methods: A total of 14 patients who underwent FEDD at our institution between November 2015 and September 2017 were retrospectively reviewed. All patients had single-level infectious spondylodiscitis and were high-risk candidates for surgery. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.02.206DOI Listing

Identifying periods of susceptibility to the impact of phthalates on children's cognitive abilities.

Environ Res 2019 Mar 5;172:604-614. Epub 2019 Mar 5.

Department of Epidemiology, Brown University, 121 South Main Street, Providence, RI, United States.

Background: Early-life phthalate exposures may adversely affect children's neurodevelopment by disrupting thyroid function, reducing gonadal hormone levels, or altering fatty acid concentrations in the brain. This study aimed to identify periods of heightened susceptibility during gestation, infancy, and childhood to the impact of phthalates on children's cognitive abilities.

Methods: We used data from 253 mother-child pairs in the Health Outcomes and Measures of the Environment (HOME) Study (Cincinnati, Ohio), a longitudinal pregnancy and birth cohort. Read More

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http://dx.doi.org/10.1016/j.envres.2019.03.009DOI Listing

The contralateral knee may not be a valid control for biomechanical outcomes after unilateral total knee arthroplasty.

Gait Posture 2019 Mar 8;70:179-184. Epub 2019 Mar 8.

Rutgers, The State University of New Jersey, School of Health Professions, Department of Rehabilitation and Movement Sciences, Physical Therapy Program North, 65 Bergen Street - Office 714A, Newark, NJ, 07107, USA.

Background: Although unilateral symptoms and unilateral total knee arthroplasty (TKA) are common, many patients have bilateral radiographic osteoarthritis (OA). Because the contralateral (non-operated) limb is often used as a comparison for clinical and biomechanical outcomes, it is important to know if the presence of OA influences movement patterns in either limb.

Research Question: The purpose of this study was to compare bilateral sagittal plane biomechanics between subjects with and without contralateral knee OA after unilateral TKA. Read More

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http://dx.doi.org/10.1016/j.gaitpost.2019.01.030DOI Listing

A view of the maternal inheritance of Espírito Santo populations: The contrast between the admixed and Pomeranian descent groups.

Forensic Sci Int Genet 2019 Mar 6;40:175-181. Epub 2019 Mar 6.

Núcleo de Genética Humana e Molecular (NGHM), Universidade Federal do Espírito Santo (UFES), Fernando Ferrari Avenue, 514 - Goiabeiras, Vitória, Espírito Santo, 29075-910, Brazil; Programa de Pós-Graduacão em Biotecnologia, Universidade Federal do Espírito Santo (UFES), Marechal Campos Avenue, 1468 - Bonfim, Vitória, Espírito Santo, 29047-105, Brazil.

In addition to its valuable utility in forensic investigations, mitochondrial DNA (mtDNA) analysis is a reliable tool to uncover the origins of admixed populations, such as Brazilians. The state of Espírito Santo (ES), similar to other coastal Brazilian states, has a population shaped by 3 main ancestral roots: Amerindian, African and European. Among the latter, the Pomeranian descendants stand out due to the preservation of the traditional aspects of their culture, especially the Pomeranian language. Read More

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http://dx.doi.org/10.1016/j.fsigen.2019.03.007DOI Listing

Penicillin allergy evaluation: A prospective, multicenter, open label evaluation of a comprehensive penicillin skin test kit.

J Allergy Clin Immunol Pract 2019 Mar 13. Epub 2019 Mar 13.

John Hopkins School of Medicine, Baltimore, MD, and AllerQuest LLC, Plainville, CT.

Background: Ten percent of the population claims an allergy to penicillin, but 90% of these individuals are not allergic. Patients labeled as penicillin-allergic have higher medical costs, longer hospital stays, are more likely to be treated with broad-spectrum antibiotics and develop drug-resistant bacterial infections. Most penicillin skin test reagents are not FDA-approved or readily available to evaluate patients labelled penicillin-allergic. Read More

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http://dx.doi.org/10.1016/j.jaip.2019.02.040DOI Listing

Morphological, ultrastructural, and phylogenetic analysis of two novel Myxobolus species (Cnidaria: Myxosporea) parasitizing bryconid fish from São Francisco River, Brazil.

Parasitol Int 2019 Mar 13. Epub 2019 Mar 13.

Department of Ecology and Evolutionary Biology, Federal University of São Paulo, Rua Professor Arthur Riedel, 275, Jardim Eldorado, CEP 09972-270 Diadema, SP, Brazil; Department of Animal Biology, Institute of Biology, University of Campinas, Caixa Postal 6109, CEP 13083-970 Campinas, SP, Brazil.

Twelve Myxobolus species have been previously described to parasitize Bryconidae fish in South America. Here, we describe two novel myxosporean species that parasitize economically important Bryconidae from the São Francisco River basin in Brazil. Myxospores morphometry, morphology, small-subunit ribosomal DNA - ssrDNA sequences, and other biological traits were used in the taxonomic analysis. Read More

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http://dx.doi.org/10.1016/j.parint.2019.03.009DOI Listing

Nursing students' cultural beliefs and understanding of dementia: A phenomenological study across three continents.

Nurse Educ Today 2019 Feb 22;77:6-11. Epub 2019 Feb 22.

University of Auckland, Level 2, Building 505, Grafton, Auckland 1142, New Zealand. Electronic address:

Background: Migrant nurses have reported difficulties adapting to their new culture and providing culturally sensitive care for people with dementia. However, to date no studies have explored the impact of student nurse's cultural heritage on their beliefs and understanding of dementia.

Objectives: To explore the cultural beliefs of dementia of student nurses studying in England, Slovenia, Philippines and New Zealand. Read More

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http://dx.doi.org/10.1016/j.nedt.2019.02.007DOI Listing
February 2019

Exploration of TiO nanoparticle mediated microdynamic therapy on Cancer treatment.

Nanomedicine 2019 Mar 13. Epub 2019 Mar 13.

Department of Orthopedics, Guangdong General Hospital, Guangdong, Academy of Medical Sciences, Guangzhou, China. Electronic address:

Radical therapy takes advantage of the reactive oxygen species produced in greater quantities within tumor cells than in normal cells. Here, for the first time, we explore a TiO nanoparticle mediated microwave induced radical therapy (termed as Microdynamic Therapy) as a new cancer treatment method. The experiments in vitro and in vivo demonstrate that colloidal TiO nanoparticles could significantly suppress the growth of osteosarcomas, even under low power (5W) microwave (MW) irradiation for 5min. Read More

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http://dx.doi.org/10.1016/j.nano.2019.02.016DOI Listing

Venom Shortages: What's an Allergist to do? Part 1, The Issues.

Ann Allergy Asthma Immunol 2019 Mar 13. Epub 2019 Mar 13.

Advocacy and Governmental Affairs, ACAAI, Louisville, KY 40223.

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http://dx.doi.org/10.1016/j.anai.2019.03.006DOI Listing

Venom Shortages: What's an Allergist to do? Part Two: Potential Solutions.

Ann Allergy Asthma Immunol 2019 Mar 13. Epub 2019 Mar 13.

Advocacy and Governmental Affairs, ACAAI, Louisville, KY 40223.

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http://dx.doi.org/10.1016/j.anai.2019.03.001DOI Listing

Experience and Reflection from China's Xiangya Medical Big Data Project.

J Biomed Inform 2019 Mar 13:103149. Epub 2019 Mar 13.

Information Security and Big Data Institute, Central South University, Changsha 410013 Hunan.

The construction of medical big data includes several problems that need to be solved, such as integration and data sharing of many heterogeneous information systems, efficient processing and analysis of large-scale medical data with complex structure or low degree of structure, and narrow application range of medical data. Therefore, medical big data construction is not only a simple collection and application of medical data but also a complex systematic project. This paper introduces China's experience in the construction of a regional medical big data ecosystem, including the overall goal of the project; establishment of policies to encourage data sharing; handling the relationship between personal privacy, information security, and information availability; establishing a cooperation mechanism between agencies; designing a polycentric medical data acquisition system; and establishing a large data centre. Read More

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http://dx.doi.org/10.1016/j.jbi.2019.103149DOI Listing

STING-mediated intestinal barrier dysfunction contributes to lethal sepsis.

EBioMedicine 2019 Mar 13. Epub 2019 Mar 13.

Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China. Electronic address:

Background: Gut integrity is compromised in abdominal sepsis with increased cellular apoptosis and altered barrier permeability. Intestinal epithelial cells (IEC) form a physiochemical barrier that separates the intestinal lumen from the host's internal milieu and is strongly involved in the mucosal inflammatory response and immune response. Recent research indicates the involvement of the stimulator of interferons genes (STING) pathway in uncontrolled inflammation and gut mucosal immune response. Read More

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http://dx.doi.org/10.1016/j.ebiom.2019.02.055DOI Listing

Harm perceptions and tobacco use initiation among youth in Wave 1 and 2 of the Population Assessment of Tobacco and Health (PATH) Study.

Prev Med 2019 Mar 13. Epub 2019 Mar 13.

Cancer Prevention & Control Program, Moores Cancer Center University of California, San Diego, United States of America; Department of Family Medicine and Public Health, University of California, San Diego, United States of America.

In the US, youth attribute higher levels of harm and addictiveness to cigarettes relative to other tobacco products. Monitoring harm perceptions across a range of tobacco products is important when forecasting risk for experimentation. This study examined data from US youth (N = 10,081) ages 12-17 from the Population Assessment of Tobacco and Health (PATH) Study who completed both Wave 1 (2013-2014) and Wave 2 (2014-2015) interviews. Read More

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http://dx.doi.org/10.1016/j.ypmed.2019.03.017DOI Listing

Dermatologic Care of Uninsured Patients Managed at Free Clinics.

J Am Acad Dermatol 2019 Mar 13. Epub 2019 Mar 13.

University of South Florida, Department of Internal Medicine.

Background: Uninsured patients are not well-tracked within the healthcare system and therefore not commonly recorded in databases. Epidemiologic data regarding patients visiting free clinics, specifically those with dermatologic concerns, is limited.

Objective: The purpose of this study is to explore the prevalence of dermatologic complaints among uninsured patients who visit free clinics. Read More

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http://dx.doi.org/10.1016/j.jaad.2019.03.010DOI Listing

Targeted mutational analysis to unravel the complexity of African horse sickness virus NS3 function in mammalian cells.

Virology 2019 Mar 9;531:149-161. Epub 2019 Mar 9.

Department of Biochemistry, Genetics and Microbiology, University of Pretoria, Private Bag X20, Hatfield, 0028, Pretoria, South Africa. Electronic address:

The African horse sickness virus non-structural protein 3 (NS3) is involved in the final stages of infection. To gain insight into the function of different NS3 domains, we generated reverse genetics-derived mutants, each expressing a modified version of the protein. A functional comparison of these mutants to the wild-type virus in mammalian cells indicated the variable contribution of the different domains to the cytopathic effect and in ensuring effective virus trafficking and release. Read More

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http://dx.doi.org/10.1016/j.virol.2019.03.005DOI Listing

When the body is the target - Representations of one's own body and bodily sensations in self-harm: A systematic review: Intended for Neuroscience and Biobehavioral Reviews.

Neurosci Biobehav Rev 2019 Mar 13. Epub 2019 Mar 13.

Perception in Action Research Centre & Department of Cognitive Science, Faculty of Human Sciences, Macquarie University & ARC Centre of Excellence in Cognition and its Disorders, Macquarie University, Sydney, NSW, Australia.

Background: Typically, we try to protect our own bodies and this is supported by internal representations that specify one's body identity, spatial parameters, and bodily sensations, but in self-harm the body becomes the target. First acts of self-harm are typically reported in adolescence. At this age, the body also becomes more salient to one's self-concept. Read More

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http://dx.doi.org/10.1016/j.neubiorev.2019.03.007DOI Listing

Breast Arterial Calcium: A Game Changer in Women's Cardiovascular Health?

JACC Cardiovasc Imaging 2019 Mar 8. Epub 2019 Mar 8.

Department of Cardiology, Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins Medical Institutions, Baltimore, Maryland; Cardiology Department, Bellvitge University Hospital and Bellvitge Biomedical Research Institute, L'Hospitalet de Llobregat, Barcelona, Spain; Research Triangle Institute Health Solutions, Pharmacoepidemiology and Risk Management, Barcelona, Spain. Electronic address:

In 2018, cardiovascular disease (CVD) was the leading cause of death among women, and current CVD prevention paradigms may not be sufficient in this group. In that context, it has recently been proposed that detection of calcification in breast arteries may help improve CVD risk screening and assessment in apparently healthy women. This review provides an overview of breast arterial anatomy; and the epidemiology, pathophysiology, and measurement of breast artery calcium (BAC); and discusses the features of the BAC-CVD link. Read More

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http://dx.doi.org/10.1016/j.jcmg.2018.07.035DOI Listing
March 2019
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Current use and training needs of point-of-care ultrasound in emergency departments: A national survey of VA hospitals.

Am J Emerg Med 2019 Feb 28. Epub 2019 Feb 28.

South Texas Veterans Health Care System, Medicine Service, San Antonio, TX, USA; UT Health San Antonio, Division of General & Hospital Medicine, San Antonio, TX, USA; (m) UT Health San Antonio, Division of Pulmonary & Critical Care Medicine, San Antonio, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajem.2019.02.043DOI Listing
February 2019

Untangling Aging Using Dynamic, Organism-Level Phenotypic Networks.

Authors:
Adam Freund

Cell Syst 2019 Mar 7. Epub 2019 Mar 7.

Calico Life Sciences, LLC, South San Francisco, CA 94080, USA. Electronic address:

Research on aging requires the ability to measure aging, and therein lies a challenge: it is impossible to measure every molecular, cellular, and physiological change that develops over time, but it is difficult to prioritize phenotypes for measurement because it is unclear which biological changes should be considered aspects of aging and, further, which species and environments exhibit "real aging." Here, I propose a strategy to address this challenge: rather than classify phenotypes as "real aging" or not, conceptualize aging as the set of all age-dependent phenotypes and appreciate that this set and its underlying mechanisms may vary by population. Use automated phenotyping technologies to measure as many age-dependent phenotypes as possible within individuals over time, prioritizing organism-level (i. Read More

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http://dx.doi.org/10.1016/j.cels.2019.02.005DOI Listing
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