666,433 results match your criteria South American Blastomycosis


Predictive Value of Preoperative Magnetic Resonance Imaging Findings for Survival and Local Recurrence in Patients Undergoing En Bloc Resection of Sacral Chordomas.

Neurosurgery 2018 Dec 12. Epub 2018 Dec 12.

Department of Neurological Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Background: Few studies have assessed the prognostic importance of preoperative magnetic resonance imaging (MRI) scan findings in patients undergoing en bloc resection of sacral chordomas.

Objective: To (1) report in-depth imaging characteristics of sacral chordomas, (2) describe the patterns of local and distant recurrence, and (3) determine imaging predictors of overall survival (OS) and local recurrence (LR).

Methods: This retrospective case series was obtained from a prospectively maintained spine database from 1995 to 2016. Read More

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December 2018

Household transmission of seasonal influenza from HIV-infected and -uninfected individuals in South Africa, 2013-2014.

J Infect Dis 2018 Dec 12. Epub 2018 Dec 12.

Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.

Background: Differential transmission from HIV-infected compared to HIV-uninfected individuals may impact influenza burden. We estimated the household secondary infection risk (SIR) and serial interval (SI) for influenza transmission from HIV-infected and HIV-uninfected index cases and identified associated factors.

Methods: Index cases were the first symptomatic person in a household with influenza-like illness, testing influenza positive on real-time reverse transcription polymerase chain reaction (rRT-PCR). Read More

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December 2018

MEASUREMENT OF EMF EXPOSURE AROUND SMALL CELL BASE STATION SITES.

Radiat Prot Dosimetry 2018 Nov 29. Epub 2018 Nov 29.

Alphawave, 3 Meson Street, Technopark, Stellenbosch, South Africa.

As mobile network technologies and usage change, mobile network cells have become smaller to meet the increased demand for data throughput. Small cell base stations are frequently used as a mobile network deployment method and are predominantly installed to service areas with a high density of people and to cover a small geographical area. Various measurement programs of the electromagnetic field (EMF) exposure have been conducted around base stations in general and these results have been published. Read More

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November 2018

Transfer RNA demethylase ALKBH3 promotes cancer progression via induction of tRNA-derived small RNAs.

Nucleic Acids Res 2018 Dec 12. Epub 2018 Dec 12.

Department of Chemistry, The University of Chicago, 929 East 57th Street, Chicago, IL 60637, USA.

Transfer RNA is heavily modified and plays a central role in protein synthesis and cellular functions. Here we demonstrate that ALKBH3 is a 1-methyladenosine (m1A) and 3-methylcytidine (m3C) demethylase of tRNA. ALKBH3 can promote cancer cell proliferation, migration and invasion. Read More

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December 2018

Validated screening tools for the assessment of cachexia, sarcopenia, and malnutrition: a systematic review.

Am J Clin Nutr 2018 Dec;108(6):1196-1208

Clinical Surgery, University of Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.

Background: There is great overlap between the presentation of cachexia, sarcopenia, and malnutrition. Distinguishing between these conditions would allow for better targeted treatment for patients.

Objectives: The aim was to systematically review validated screening tools for cachexia, sarcopenia, and malnutrition in adults and, if a combined tool is absent, make suggestions for the generation of a novel screening tool. Read More

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December 2018

Immune system stimulation increases dietary threonine requirements for protein deposition in growing pigs.

J Anim Sci 2018 Dec 12. Epub 2018 Dec 12.

Department of Animal and Food Sciences, Texas Tech University, Lubbock, Texas.

Previous studies have reported an increase in the utilization of threonine (Thr) during immune system stimulation (ISS). However, increased utilization of an amino acid (AA) during ISS may not reflect an increased dietary requirement, as endogenous sources may supply AA to meet the need for enhanced utilization. The current study evaluated the impact of ISS on components of dietary Thr requirements, i. Read More

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December 2018

Targeting cervical cancer campaigns on teenage high schoolers in resource-limited economies: lessons from an intervention study of Nigerian senior secondary school girls.

Fam Pract 2018 Dec 12. Epub 2018 Dec 12.

Department of Community Medicine and Primary Healthcare, Chukwuemeka Odumegwu Ojukwu University/University Teaching Hospital, Awka, Nigeria.

Background: Given the dearth of government-sponsored programmes, preventive lifestyles and practices are the realistic hopes for millions of women in developing countries against cervical cancer. Early interventions for teenage high school girls have been advocated recently, but evidence-base for sustainable activities at this demographic is lacking. This article reduces this gap by determining the impact of two cervical cancer education techniques. Read More

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December 2018

Widespread co-occurrence of multiple ploidy levels in fragile ferns (Cystopteris fragilis complex; Cystopteridaceae) probably stems from similar ecology of cytotypes, their efficient dispersal and inter-ploidy hybridization.

Ann Bot 2018 Dec 12. Epub 2018 Dec 12.

Department of Botany, Faculty of Science, University of South Bohemia, Branišovská, Ceské Budejovice, Czech Republic.

Background And Aims: Polyploidy has played an important role in the evolution of ferns. However, the dearth of data on cytotype diversity, cytotype distribution patterns and ecology in ferns is striking in comparison with angiosperms and prevents an assessment of whether cytotype coexistence and its mechanisms show similar patterns in both plant groups. Here, an attempt to fill this gap was made using the ploidy-variable and widely distributed Cystopteris fragilis complex. Read More

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December 2018

Functionally distinct assembly of vascular plants colonizing alpine cushions suggests their vulnerability to climate change.

Ann Bot 2018 Dec 12. Epub 2018 Dec 12.

Institute of Botany, The Czech Academy of Sciences, Průhonice, Czech Republic.

Background And Aims: Alpine cushion plants can initially facilitate other species during ecological succession, but later on can be negatively affected by their development, especially when beneficiaries possess traits allowing them to overrun their host. This can be reinforced by accelerated warming favouring competitively strong species over cold-adapted cushion specialists. However, little empirical research has addressed the trait-based mechanisms of these interactions. Read More

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December 2018

Backscattered electron imaging of high pressure frozen soybean root nodules visualizes formation of symbiosome membranes.

Microscopy (Oxf) 2018 Dec 12. Epub 2018 Dec 12.

Comprehensive Analysis Center for Science, Saitama University, Saitama, Japan.

High-pressure frozen soybean root nodules were fractured and backscattered electron images were obtained from uncoated samples in a low vacuum scanning electron microscope equipped with a cryo-transfer system. Structures of infected cells were well preserved: numerous symbiosomes, as well as nuclei, plastids and mitochondria were observed without ice crystal damage. After appropriate sublimation of water, bacteria included in symbiosomes were visualized. Read More

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December 2018

Simultaneous operative repair of pectus excavatum and concurrent congenital heart defects.

Interact Cardiovasc Thorac Surg 2018 Dec 11. Epub 2018 Dec 11.

Department of Cardiothoracic Surgery, Hunan Children's Hospital, Changsha, China.

Objectives: The aim of this study is to describe an effective surgical strategy for the treatment of children with pectus excavatum (PE) and concurrent congenital heart defect (CHD).

Methods: We retrospectively reviewed the medical records of all children (n = 16) who underwent simultaneous repair of PE with concurrent CHD at the Hunan Children's Hospital from July 2007 to December 2017. Among them, 7 patients had a simple atrial septal defect (ASD); 4 patients had a simple ventricular septal defect (VSD); 3 patients had both VSD and ASD; 1 patient had VSD, ASD and patent ductus arteriosus; and 1 patient had VSD complicated by pulmonary hypertension. Read More

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December 2018

V2-Directed Vaccine-like Antibodies from HIV-1 Infection Identify an Additional K169-Binding Light Chain Motif with Broad ADCC Activity.

Cell Rep 2018 Dec;25(11):3123-3135.e6

National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg 2131, South Africa; Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2000, South Africa; Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu Natal, Durban 4041, South Africa. Electronic address:

Antibodies that bind residue K169 in the V2 region of the HIV-1 envelope correlated with reduced risk of infection in the RV144 vaccine trial but were restricted to two ED-motif-encoding light chain genes. Here, we identify an HIV-infected donor with high-titer V2 peptide-binding antibodies and isolate two antibody lineages (CAP228-16H/19F and CAP228-3D) that mediate potent antibody-dependent cell-mediated cytotoxicity (ADCC). Both lineages use the IGHV5-51 heavy chain germline gene, similar to the RV144 antibody CH58, but one lineage (CAP228-16H/19F) uses a light chain without the ED motif. Read More

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December 2018

Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis.

Cell Rep 2018 Dec;25(11):3036-3046.e6

Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta, GA 30912, USA; Georgia Cancer Center, Augusta University, Augusta, GA 30912, USA; Charlie Norwood VA Medical Center, Augusta, GA 30904, USA. Electronic address:

IL-10 functions as a suppressor of colitis and colitis-associated colon cancer, but it is also a risk locus associated with ulcerative colitis. The mechanism underlying the contrasting roles of IL-10 in inflammation and colon cancer is unknown. We report here that inflammation induces the accumulation of CD11bGr1 myeloid-derived suppressor cells (MDSCs) that express high levels of IL-10 in colon tissue. Read More

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December 2018

Are metal artefact reduction algorithms effective to correct cone beam CT artefacts arising from the exomass?

Dentomaxillofac Radiol 2018 Dec 12:20180290. Epub 2018 Dec 12.

1 Department of Oral Diagnosis, Division of Oral Radiology, Piracicaba Dental School, University of Campinas , Piracicaba , Brazil.

The aim of this study was to evaluate the effectiveness of metal artefact reduction (MAR) in cone beam computed tomography (CBCT) artefacts arising from metallic objects in the exomass. A radiographic phantom composed of 16 polypropylene tubes filled with a homogeneous radiopaque solution was created. CBCT scans were obtained with two units: Picasso Trio (Vatech, South Korea) and ProMax (Planmeca, Finland). Read More

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December 2018

Another Weapon in the Battle Against Idiopathic Pulmonary Fibrosis?

Am J Respir Cell Mol Biol 2018 Dec 12. Epub 2018 Dec 12.

University of Washington, Medicine, Division of Pulmonary Critical Care, Seattle, Washington, United States.

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December 2018

Destructive lesion of the temporomandibular joint: A case of tophaceous pseudogout.

Ear Nose Throat J 2018 Dec;97(12):E18-E20

Department of Otolaryngology-Head and Neck Surgery, Virginia Commonwealth University, West Hospital, 1200 East Broad St., 12th Floor, South Wing, Suite 313, Box 980146, Richmond, VA 23298-0146, USA.

Tophaceous pseudogout of the temporomandibular joint is a rare entity that clinically and radiographically mimics neoplastic or infectious conditions. Diagnosis requires histopathologic examination. Given the rarity of this condition, there is a paucity of information pertaining to the surgical approach, reconstructive options, and postoperative outcomes. Read More

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December 2018

Changes of sexual risk behaviors and sexual connections among HIV-positive men who have sex with men along their HIV care continuum.

PLoS One 2018 12;13(12):e0209008. Epub 2018 Dec 12.

Stanley Ho Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Hong Kong.

Background: While HIV incidence among men who have sex with men (MSM) is increasing in Hong Kong, unprotected sex apparently remains prevalent among those infected but virally non-suppressed. Little is known about how sexual behaviours and sexual connections may change among MSM along their HIV care continuum.

Methods: In this retrospective cross-sectional study, HIV-positive MSM attending the largest HIV specialist clinic in Hong Kong between October and December 2014 were invited to complete a self-administrated structured questionnaire. Read More

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December 2018

Characterization of grapevine leafroll-associated virus 3 genetic variants and application towards RT-qPCR assay design.

PLoS One 2018 12;13(12):e0208862. Epub 2018 Dec 12.

Department of Plant Pathology, University of California-Davis, Davis, California, United States of America.

Grapevine leafroll-associated virus 3 (GLRaV-3) is the most widely prevalent and economically important of the complex of RNA viruses associated with grapevine leafroll disease (GLD). Phylogenetic studies have grouped GLRaV-3 isolates into nine different monophyletic groups and four supergroups, making GLRaV-3 a genetically highly diverse virus species. In addition, new divergent variants have been discovered recently around the world. Read More

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December 2018

Differential gene expression between the vigorous and dwarf litchi cultivars based on RNA-Seq transcriptome analysis.

PLoS One 2018 12;13(12):e0208771. Epub 2018 Dec 12.

State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources/Key Laboratory of Biology and Genetic Improvement of Horticultural Crops (South China) in Ministry of Agriculture, College of Horticulture, South China Agricultural University, Guangzhou, China.

Litchi (Litchi chinesis Sonn.) is the most economically significant member of Sapindaceae family, especially in sub-tropical regions. However, its tall tree body often brings many inconveniences to production management. Read More

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December 2018

Decoupling environmental effects and host population dynamics for anthrax, a classic reservoir-driven disease.

PLoS One 2018 12;13(12):e0208621. Epub 2018 Dec 12.

Spatial Epidemiology and Ecology Research Laboratory, Department of Geography, University of Florida, Gainesville, Florida, United States of America.

Quantitative models describing environmentally-mediated disease transmission rarely focus on the independent contribution of recruitment and the environment on the force of infection driving outbreaks. In this study we attempt to investigate the interaction between external factors and host's population dynamics in determining the outbreaks of some indirectly transmitted diseases. We first built deterministic and stochastic compartmental models based on anthrax which were parameterized using information from literature and complemented with field observations. Read More

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December 2018

Genome-wide identification and characterization of gene family for RWP-RK transcription factors in wheat (Triticum aestivum L.).

PLoS One 2018 12;13(12):e0208409. Epub 2018 Dec 12.

Department of Genetics and Plant Breeding, CCS University, Meerut, India.

RWP-RKs represent a small family of transcription factors (TFs) that are unique to plants and function particularly under conditions of nitrogen starvation. These RWP-RKs have been classified in two sub-families, NLPs (NIN-like proteins) and RKDs (RWP-RK domain proteins). NLPs regulate tissue-specific expression of genes involved in nitrogen use efficiency (NUE) and RKDs regulate expression of genes involved in gametogenesis/embryogenesis. Read More

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December 2018

New skeletal material sheds light on the palaeobiology of the Pleistocene marsupial carnivore, Thylacoleo carnifex.

PLoS One 2018 12;13(12):e0208020. Epub 2018 Dec 12.

Ecology and Evolution, College of Science and Engineering, Flinders University, Adelaide, South Australia, Australia.

The extinct marsupial 'lion' Thylacoleo carnifex was Australia's largest mammalian carnivore. Despite being the topic of more discussion than any other extinct Australian marsupial (excepting perhaps the Thylacine), basic aspects of its palaeobiology, including its locomotory repertoire, remain poorly understood. Recent discoveries allowed the first reconstruction of an entire skeleton including the first complete tail and hitherto-unrecognised clavicles. Read More

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December 2018

Low 25-hydroxyvitamin D levels are more prevalent in Canadians of South Asian than European ancestry inhabiting the National Capital Region of Canada.

PLoS One 2018 12;13(12):e0207429. Epub 2018 Dec 12.

Bureau of Nutritional Sciences, Health Products and Food Branch, Health Canada, Ottawa, ON, Canada.

The US Institute of Medicine defined serum 25-hydroxyvitamin D (25OHD) cut point values of 30 nmol/L and 40 nmol/L were used to assess the vitamin D status of South Asian and European Canadians of self-identified ancestry living in the National Capital Region of Canada. Serum 25OHD values were measured in the spring and fall of 2012 to represent status during the winter and summer months, respectively. A total of 1238 measurements were obtained from 669 participants (49% South Asian ancestry): some participants were measured only once (spring or fall). Read More

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December 2018
1 Read

Retail-based healthy food point-of-decision prompts (PDPs) increase healthy food choices in a rural, low-income, minority community.

PLoS One 2018 12;13(12):e0207792. Epub 2018 Dec 12.

Rosebud Food Sovereignty Initiative, Mission, South Dakota, United States of America.

This study examines the potential for point-of-decision prompts (PDPs) to promote healthier food choices among shoppers in a rural, low-income, minority community. We hypothesized that a narrowly defined PDP (focused on fresh produce) would be easier for shoppers to remember than a broadly defined PDP (focused on any healthy items), resulting in a higher proportion of healthy items purchased. PDPs were placed at the entrance to a supermarket in Mission, South Dakota, United States of America, on the Rosebud Sioux Reservation for alternating time periods, July 9-10, 2017. Read More

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December 2018

Analysis and insights into recombination signals in lumpy skin disease virus recovered in the field.

PLoS One 2018 12;13(12):e0207480. Epub 2018 Dec 12.

Federal Center for Animal Health, Vladimir, Russia.

Wide spread incidences of vaccine-like strains of lumpy skin disease virus (LSDV) have recently been reported in a Russian region with a neighboring country that actively vaccinate with a live attenuated LSD vaccine. The use of live-attenuated viruses (LAVs) as vaccines during an active outbreak, creates potential ground for coinfection of hosts and emergence of a strain combining genetic fragments of both parental vaccine and field strains. In this study, we analyse the vaccine-like strain LSDV RUSSIA/Saratov/2017 detected in Saratovskaya oblast, a region sharing border with Kazakhstan. Read More

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December 2018
1 Read

Usefulness of baseline statin therapy in non-obstructive coronary artery disease by coronary computed tomographic angiography: From the CONFIRM (COronary CT Angiography EvaluatioN For Clinical Outcomes: An InteRnational Multicenter) study.

PLoS One 2018 12;13(12):e0207194. Epub 2018 Dec 12.

Department of Radiology, NewYork-Presbyterian Hospital and the Weill Cornell Medical College, New York, New York, United States of America.

Background: The extent to which the presence and extent of subclinical atherosclerosis by coronary computed tomography angiography influences a potential mortality benefit of statin is unknown. We evaluated the relationship between statin therapy, mortality, and subclinical atherosclerosis.

Methods: In the CONFIRM study, patients with normal or non-obstructive plaque (<50% diameter stenosis) for whom data on baseline statin use was available were included. Read More

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December 2018

Novel Application of the Pfirrmann Disc Degeneration Grading System to 9.4T MRI: Higher Reliability Compared to 3T MRI.

Spine (Phila Pa 1976) 2018 Dec 11. Epub 2018 Dec 11.

Department of Neurosurgery, Monash Medical Centre, Clayton, Victoria, Australia.

Study Design: Reliability Study.

Objective: To evaluate the applicability and reliability of 9.4T MRI in the assessment of degenerative disc disease compared to 3T MRI. Read More

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December 2018

Differential Gene Expression in Erlotinib-treated Fibroblasts.

Nurs Res 2018 Dec 12. Epub 2018 Dec 12.

Assistant Professor, University of South Carolina, College of Nursing, Columbia, SC Bioinformatics Analyst I, University of Maryland, Baltimore, School of Medicine, Institute for Genome Sciences, Baltimore, MD Professor, Chair, Department of Hematology/Oncology, Deputy Director of the Cancer Center for Clinical Research, G. Morris Dorrance Chair in Medical Oncology, Fox Chase Cancer Center, Philadelphia, PA Bioinformatics Analyst II, University of Maryland, School of Medicine, Institute for Genome Sciences, Baltimore, MD Laboratory Research Technician, University of Maryland, Baltimore, School of Nursing, Baltimore, MD Professor, Chair, Department of Pain and Translational Symptom Science, University of Maryland, Baltimore, School of Nursing, Baltimore, MD.

Background: Therapies targeting the epidermal growth factor receptor (EGFR) result in a painful rash, the most common and debilitating toxicity among patients with non-small cell lung cancer (NSCLC) who take EGFR tyrosine kinase inhibitor (TKI) therapy; however, predicting the development and the severity of the rash is difficult.

Objective: To examine how erlotinib-an EGFR TKI that NSCLC patients take to stop or slow tumor growth-altered the transcriptome of dermal fibroblasts.

Methods: Dermal fibroblasts (ATCC® PCS-201-012™) were seeded in cell culture flasks, grown under standard conditions, and transferred to cell culture dishes. Read More

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December 2018

Application of the ConNECT Framework to Precision Health and Health Disparities.

Nurs Res 2018 Dec 12. Epub 2018 Dec 12.

Professor and Associate Vice Dean of Research, University of South Florida College of Nursing, Tampa, FL Founding Director, Center of Community Alliance for Research Education, Professor, Department of Population Sciences, Beckman Research Institute, City of Hope Medical Center, Duarte, CA Associate Professor, The Ohio State University, College of Nursing, Columbus, OH Department of Health Outcomes and Behavior, Division of Population Science, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612 Assistant Professor, College of Nursing, University of Utah, Salt Lake City, UT Professor, Department of Psychological Science, University of North Carolina at Charlotte, Charlotte, NC Senior Member, Division of Population Science, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL Department of Health Disparities Research, MD Anderson Cancer Center, Houston, TX Division of Population Science, H. Lee Moffitt Cancer Center and Research Institute & Department of Oncological Sciences, University of South Florida, College of Medicine, Tampa, FL Assistant Professor, Department of Oncology Sciences, Icahn School of Medicine at Mount Sinai, New York, NY Assistant Professor, Department of Community Health Sciences, Boston University School of Public Health and Department of Social and Behavioral Sciences, and Harvard T.H. Chan School of Public Health, Boston, MA Assistant Professor, Department of Medical Social Sciences and Robert H. Lurie Comprehensive Cancer Center at Northwestern University Feinberg School of Medicine, Chicago, IL Associate Professor, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR Staff Scientist, Project Director, Biobehavioral Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA Strategic Director of Health Disparities Research, Behavioral Research Center, American Cancer Society, Atlanta, GA.

Background: An emphasis on precision health (PH) has stimulated precision medicine studies to focus on the interplay of biological, behavioral, and environmental factors with disease risks, treatments, prognoses, and outcomes affecting health disparities. It is imperative, as well, that improving health equity among underserved populations remains central to the efforts and aims of PH.

Objectives: Apply the transdisciplinary ConNECT Framework: A model for advancing behavioral medicine science and practice to foster health equity to PH by integrating a population health agenda for reducing health disparities. Read More

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December 2018

Hemodynamic effects of the dipeptidyl peptidase-4 inhibitor linagliptin with renin-angiotensin system inhibitors in type 2 diabetic patients with albuminuria.

J Hypertens 2018 Dec 11. Epub 2018 Dec 11.

Boehringer Ingelheim International GmbH, Ingelheim.

Objective: Concomitant treatment with angiotensin-converting enzyme (ACE) inhibitors and dipeptidyl peptidase-4 (DPP-4) inhibitors is increasingly common. Pharmacological studies have suggested a potential adverse drug interaction between ACE inhibitors and DPP-4 inhibitors resulting in unfavorable hemodynamic changes; very few studies have examined such an interaction between angiotensin II receptor blockers (ARBs) and DPP-4 inhibitors. We investigated blood pressure (BP) and heart rate (HR) during treatment with the DPP-4 inhibitor linagliptin in individuals receiving either ACE inhibitors or ARBs in the MARLINA-T2D trial. Read More

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December 2018

Examining our four priorities: Commentary from the guest editors.

J Am Assoc Nurse Pract 2018 Dec;30(12):724-726

Nursing Practice and Acute Care Nurse Practitioner Programs, Seton Hall University, College of Nursing, South Orange, New Jersey.

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December 2018

The Prognostic Value of 18F-FDG Uptake in the Supraclavicular Lymph Node (N3c) on PET/CT in Patients With Locally Advanced Breast Cancer With Clinical N3c.

Clin Nucl Med 2019 Jan;44(1):e6-e12

From the Departments of Nuclear Medicine, and.

Purpose: We investigated the prognostic value of F-FDG uptake in the supraclavicular lymph node (SCLN) on PET/CT in breast cancer patients with clinical ipsilateral SCLN metastasis (cN3c).

Methods: Fifty-five female patients with initial F-FDG PET/CT were treated with curative intent. For semiquantitative analysis, the SUVmax of the primary tumor, axillary lymph node, and SCLN were normalized by the SUVmean of the liver (defined as SUVR-tumor, SUVR-axillary lymph node, and SUVR-SCLN, respectively). Read More

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January 2019
1 Read

Near-miss crashes and other predictors of motorcycle crashes: Findings from a population-based survey.

Traffic Inj Prev 2018 Dec 12:1-7. Epub 2018 Dec 12.

d Accident Research Centre, Monash University , Melbourne , Victoria , Australia.

Objective: Crash and injury surveillance studies have identified a range of rider-related factors, including age, sex, licensure, training and experience, as being associated with motorcycle crash risk. The aim of this study was to establish whether these previously identified factors were associated with crash involvement in an Australian-based population.

Methods: Data obtained from motorcyclists recruited from road authority licensing offices in a population-based survey design were analyzed. Read More

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December 2018

Amelioration of amyloid β-FcγRIIb neurotoxicity and tau pathologies by targeting LYN.

FASEB J 2018 Dec 12:fj201800926R. Epub 2018 Dec 12.

School of Biological Sciences, Seoul National University, Seoul, South Korea; and.

SRC-family kinases (SFKs) have been implicated in Alzheimer's disease (AD), but their mode of action was scarcely understood. Here, we show that LYN plays an essential role in amyloid β (Aβ)-triggered neurotoxicity and tau hyperphosphorylation by phosphorylating Fcγ receptor IIb2 (FcγRIIb2). We found that enzyme activity of LYN was increased in the brain of AD patients and was promoted in neuronal cells exposed to Aβ 1-42 (Aβ). Read More

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December 2018

Real-time Mobile Monitoring of the Dynamic Associations Among Motor Activity, Energy, Mood, and Sleep in Adults With Bipolar Disorder.

JAMA Psychiatry 2018 Dec 12. Epub 2018 Dec 12.

Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

Importance: Biologic systems involved in the regulation of motor activity are intricately linked with other homeostatic systems such as sleep, feeding behavior, energy, and mood. Mobile monitoring technology (eg, actigraphy and ecological momentary assessment devices) allows the assessment of these multiple systems in real time. However, most clinical studies of mental disorders that use mobile devices have not focused on the dynamic associations between these systems. Read More

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December 2018

Correction: Comment on "Negative effective Li transference numbers in Li salt/ionic liquid mixtures: does Li drift in the "Wrong" direction?" by M. Gouverneur, F. Schmidt and M. Schönhoff, Phys. Chem. Chem. Phys., 2018, 20, 7470.

Authors:
Kenneth R Harris

Phys Chem Chem Phys 2018 Dec 12. Epub 2018 Dec 12.

School of Physical, Environmental and Mathematical Sciences, The University of New South Wales, Australian Defence Force Academy, PO Box 7916, Canberra BC, ACT 2610, Australia.

Correction for 'Comment on "Negative effective Li transference numbers in Li salt/ionic liquid mixtures: does Li drift in the "Wrong" direction?" by M. Gouverneur, F. Schmidt and M. Read More

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December 2018

The influence of cholesterol on melittin lipidation in neutral membranes.

Phys Chem Chem Phys 2018 Dec 12. Epub 2018 Dec 12.

Chemistry Department, Durham University, South Road, Durham, DH1 3LE, UK.

The effects of cholesterol on the process of intrinsic lipidation, whereby an acyl chain is transferred from a lipid as donor to a membrane-associated acceptor molecule, have been explored using melittin as the acceptor. Membranes comprising lipids with saturated acyl chains (1,2-dipalmitoyl sn-glycero-3-phosphocholine, DPPC; 1,2-dimyristoyl sn-glycero-3-phosphocholine, DMPC) yielded no acyl transfer, whereas membranes composed of lipids with unsaturated acyl chains (1,2-dioleoyl sn-glycero-3-phosphocholine, DOPC; 1-palmitoyl-2-oleoyl sn-glycero-3-phosphocholine, POPC) produced detectable lipidation activity. For all lipids, inclusion of cholesterol led to a significant increase in lipidation activity, with the greatest effect observed for 20 mol% cholesterol in POPC. Read More

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December 2018

Fluorescein sodium ligand-modified silicon nanoparticles produce ultrahigh fluorescence with robust pH- and photo-stability.

Chem Commun (Camb) 2018 Dec 12. Epub 2018 Dec 12.

Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Institute of Functional Nano & Soft Materials (FUNSOM), and Collaborative Innovation Centre of Suzhou Nano Science and Technology (NANO-CIC), Soochow University, Suzhou, Jiangsu 215123, China.

Water-dispersed silicon nanoparticles (SiNPs) are facilely prepared in an aqueous phase via microwave-assisted synthesis. The whole synthetic procedure is accomplished in a one-pot microwave reaction, without the requirement of additional surface modification. Remarkably, the resultant SiNPs feature ultrahigh fluorescence (photoluminescent quantum yield (PLQY): ∼90%), robust pH- and photo-stability, and favourable biocompatibility. Read More

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December 2018

Lysobacter tabacisoli sp. nov., isolated from rhizosphere soil of Nicotiana tabacum L.

Int J Syst Evol Microbiol 2018 Dec 12. Epub 2018 Dec 12.

1​State Key Laboratory of Biocontrol and Guangdong Provincial Key Laboratory of Plant Resources, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, PR China.

A Gram-stain-negative, aerobic, rod-shaped bacterium, designated strain C8-1, was isolated from the rhizosphere soil of Nicotiana tabacum L. collected from Kunming, south-west China. The cells showed oxidase-positive and catalase-positive reactions. Read More

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December 2018

Pedobacter miscanthi sp. nov., isolated from Miscanthus sinensis.

Int J Syst Evol Microbiol 2018 Dec 12. Epub 2018 Dec 12.

3​Northwest Hubei Research Institute of Traditional Fermented Food, College of Food Science and Technology, Hubei University of Arts and Science, Xiangyang 441053, PR China.

In a survey of endophytic bacteria in Miscanthus sinensis, a strain of Gram-negative, non-endospore-forming, rod-shaped, aerobic bacterium was isolated and designated as RS10. Phylogenetic analysis based on its 16S rRNA gene sequence showed that the strain RS10 was affiliated with the genus Pedobacter and exhibited the highest sequence similarities to Pedobacter kyungheensis KACC 16221 (97.78 %), Pedobacter roseus KCTC 22187 (97. Read More

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December 2018

Variations in lower body stiffness during sports-specific tasks in well-trained female athletes.

Sports Biomech 2018 Dec 12:1-16. Epub 2018 Dec 12.

a School of Exercise Science, Faculty of Health Science , Australian Catholic University , Strathfield , Australia.

The present study aimed to assess the differences in leg stiffness and the associated performance variables between athletes from various training backgrounds during tasks relevant to athletic training. Forty-seven female participants (20 nationally identified netballers, 13 high-level endurance athletes and 14 age-matched controls) completed a sprint, anticipated sidestep change of direction and unilateral repetitive hopping task to assess leg stiffness and the relationship of stiffness between the different tasks. Leg stiffness and performance variables were evaluated with a 10-camera motion analysis system and force plate, and leg stiffness was derived through the McMahon and Cheng methodology (1990). Read More

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December 2018

Visible-Light-Promoted Transition-Metal-Free Phosphinylation of Heteroaryl Halides in the Presence of Potassium tert-Butoxide.

Org Lett 2018 Dec 12. Epub 2018 Dec 12.

State Key Laboratory of Synthetic Chemistry, and Department of Chemistry , The University of Hong Kong , Pokfulam Road, Hong Kong , China.

A novel visible-light-promoted C-P bond formation reaction in the absence of both transition metal and photoredox catalysts is disclosed. By employing easily available and inexpensive heteroaryl chlorides/bromides as substrates, a variety of heteroaryl phosphine oxides were obtained in moderate to good yields. This strategy provides a simple and efficient route to heteroaryl phosphine oxides. Read More

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December 2018

Trichothecrotocins A-C, Antiphytopathogenic Agents from Potato Endophytic Fungus Trichothecium crotocinigenum.

Org Lett 2018 Dec 12. Epub 2018 Dec 12.

School of Pharmaceutical Sciences , South-Central University for Nationalities , Wuhan 430074 , China.

Two trichothecene sesquiterpenoids, trichothecrotocins A (1) and B (2), and a merosesquiterpenoid racemate, (±)-trichothecrotocin C (3), were obtained from potato endophytic fungus Trichothecium crotocinigenum by bioguided isolation. Their structures were elucidated by extensive spectroscopic methods, electronic circular dichroism calculations, and single-crystal X-ray diffraction. Compounds 1 and 2 are trichothecenes possessing new ring systems. Read More

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December 2018

Primary malignant tumors of the adrenal glands.

Clinics (Sao Paulo) 2018 Dec 10;73(suppl 1):e756s. Epub 2018 Dec 10.

Unidade de Suprarrenal, Laboratorio de Hormonios e Genetica Molecular LIM/42, Servico de Endocrinologia e Metabologia, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.

Malignancy must be considered in the management of adrenal lesions, including those incidentally identified on imaging studies. Adrenocortical carcinomas (ACCs) are rare tumors with an estimated annual incidence of 0.7-2 cases per year and a worldwide prevalence of 4-12 cases per million/year. Read More

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December 2018

IN TIME: THE VALUE AND GLOBAL IMPLICATIONSOF NEWBORN SCREENING FORSEVERE COMBINED IMMUNODEFICIENCY.

Rev Paul Pediatr 2018 Oct-Dec;36(4):388-397

Divisão de Alergia e Imunologia, Children's Research Institute, University of South Florida, St. Petersburg, FL, Estados Unidos.

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Characterisation of plasmid-mediated rmtB-1 in Enterobacteriaceae clinical isolates from São Paulo, Brazil.

Mem Inst Oswaldo Cruz 2018 Dec 10;113(12):e180392. Epub 2018 Dec 10.

Universidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Medicina Interna, Divisão de Doenças Infecciosas, Laboratório Alerta, São Paulo, SP, Brasil.

OBJECTIVES The emergence of 16S rRNA methyltranferases (16 RMTAses) has jeopardised the clinical use of aminoglycosides. RmtB is one of the most frequently reported in Gram-negatives worldwide. In this study, we aimed to estimate the frequency of 16S RMTAses encoding genes in Enterobacteriaceae isolated in a three-month period from a tertiary Brazilian hospital. Read More

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December 2018

The production of care in the routine of Family Health Teams.

Rev Bras Enferm 2018 ;71(suppl 6):2659-2665

Universidade Federal do Estado do Rio de Janeiro. Rio de Janeiro, Rio de Janeiro, Brasil.

Objective: To identify the factors interfering in the production of care in the daily work of health professionals from the Primary Health Care.

Method: Qualitative research carried out with Family Health Strategy (FHS) teams, in the health units of Rocinha (Rocinha is a favela located in the South Zone of the city of Rio de Janeiro, Brazil). To analyze the data, the thematic network proposed by Attride-Stirling was used. Read More

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January 2018

Formation and disruption of bonds between caregivers and institutionalized children.

Rev Bras Enferm 2018 ;71(suppl 6):2650-2658

Universidade Federal de Pelotas, Nursing School. Pelotas, Rio Grande do Sul, Brazil.

Objective: to understand the perspective of caregivers about the formation and disruption of bonds with institutionalized children.

Method: a qualitative research that used as a theoretical framework the Attachment Theory and the Symbolic Interactionism, and the Grounded Theory as methodological framework. Participating in the study were 15 female caregivers of children aged zero to three years, from a child care institution in the south of Brazil, from April to July 2015. Read More

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January 2018

Brazilian National School Food Program as a promoter of local, healthy and sustainable food systems: evaluating the financial implementation.

Cien Saude Colet 2018 Dec;23(12):4189-4197

Programa de Pós-Graduação em Nutrição, Departamento de Nutrição, Centro de Ciências da Saúde, Universidade Federal de Santa Catarina. Florianópolis SC Brasil.

This study aimed to analyze the financial investment used for the procurement of food for the Brazilian National School Food Program (PNAE) in a city in the South of Brazil. The bidding process, the public calls and accountability reports of the PNAE were analyzed in the following variables: I) municipal financial complementation values; II) percentage of resources used to purchase foods from Family Farmer (FF), and Recommended, Restricted, Prohibited and others foods. The comparison of proportions was employed as a test to identify differences between investments. Read More

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December 2018

Clinical Features of Primary Familial Brain Calcification in 17 Families.

Chin Med J (Engl) 2018 Dec;131(24):2997-3000

Department of Clinical Pharmacology, Xiangya Hospital Central South University, Changsha, Hunan 410008, China.

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December 2018
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