47,790 results match your criteria Solitary Pulmonary Nodule Imaging


Daily energy expenditure of males following alternative reproductive tactics: Solitary roamers spend more energy than group-living males.

Physiol Behav 2018 Dec 3. Epub 2018 Dec 3.

School of Animal, Plant & Environmental Sciences, University of the Witwatersrand, Private Bag 3, WITS, 2050 Johannesburg, South Africa; IPHC, UNISTRA, CNRS, 23 rue du Loess, 67200 Strasbourg, France.

In many species, males follow alternative reproductive tactics (ARTs), where one tactic (called bourgeois) has much higher reproductive success than alternative tactics followed by males with lower competitive ability. The extent to which ARTs differ in energetic costs is unknown, but it is important to understand the fitness payoffs of ARTs. We studied male African striped mice (Rhabdomys pumilio) which follow one of three ARTs: heavy bourgeois males defend harems of females and have 10 times higher reproductive success than smaller roamers, which have ten times higher reproductive success than philopatric males, which remain in their natal group and are the smallest males. Read More

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December 2018

Cellular and Molecular Mechanisms of Regeneration in colonial and solitary Ascidians.

Dev Biol 2018 Dec 3. Epub 2018 Dec 3.

Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, CA USA.

Regenerative ability is highly variable among the metazoans. While many invertebrate organisms are capable of complete regeneration of entire bodies and organs, whole-organ regeneration is limited to very few species in the vertebrate lineages. Tunicates, which are invertebrate chordates and the closest extant relatives of the vertebrates, show robust regenerative ability. Read More

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December 2018
1 Read

A Rare Diagnosis After the Fall of a 96-Year-Old Woman: Doege-Potter Syndrome.

Curr Aging Sci 2018 Dec 5. Epub 2018 Dec 5.

Acute Geriatrics Unit, Monza (MB). Italy.

Introduction: Doege-Potter syndrome (DPS) is a rare but life-threatening paraneoplastic syndrome, characterized by non-islet cell tumor-induced hypoglycemia (NICTH) secondary to a solitary fibrous tumor (SFT), which secretes an incompletely processed form of insulin-like growth factor 2 (IGF-2).

Results: A 96-year-old woman was admitted with head trauma due to an accidental fall. During her hospital stay she experienced frequent hypoglycemic episodes. Read More

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December 2018

Structural and Mass Spectrometric Imaging Analyses of Adhered Tunic and Adhesive Projections of Solitary Ascidians.

Zoolog Sci 2018 Dec;35(6):535-547

2 Natural Science Center for Basic Research and Development, Hiroshima University, 1-4-2 Kagamiyama, Higashi-hiroshima, Hiroshima 739-8521, Japan.

Most ascidian species settle on underwater substrates during a short free-swimming tadpole larval period. During this process, "rapid adhesion" occurs on adhesive papillae located at the anterior region of the cephalenteron. Settled and transformed ascidians subsequently expand the attachment area by "slow adhesion" with ampullae. Read More

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December 2018

Dermoscopic follow-up of therapeutic response in mantle cell lymphoma with secondary involvement of the scalp.

J Cosmet Dermatol 2018 Dec 5. Epub 2018 Dec 5.

The Department of Bone Marrow Transplantation and Onco-Hematology, Maria Sklodowska-Curie Institute - Oncology Center, Gliwice Branch, Gliwice, Poland.

The scalp is a potential location for both benign and malignant tumors. Lymphoproliferative diseases can involve the skin as a primary or secondary manifestation. Dermoscopy is a noninvasive diagnostic tool for rapid diagnosis, screening, and follow-up of the majority of skin tumors. Read More

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December 2018
2 Reads

A 17-year-old woman with a solitary, mixed squamous cell and glandular papilloma of the bronchus.

Respirol Case Rep 2019 Feb 30;7(2):e00393. Epub 2018 Nov 30.

Department of Respiratory Medicine Kyorin University School of Medicine Tokyo Japan.

A 17-year-old woman was referred to our hospital due to cough on exertion and right chest pain over the previous two months, together with bloody sputum over the previous week. Chest X-ray demonstrated a nodule measuring 3 cm in diameter in the right middle lung field. On repeated bronchoscopy, the tumour was recognized as a rapidly growing intra-bronchial protruded tumour at the orifice of the right B8. Read More

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February 2019

Genetic evidence of female kin clusters in a continuous population of a solitary carnivore, the Eurasian lynx.

Ecol Evol 2018 Nov 17;8(22):10964-10975. Epub 2018 Oct 17.

NIBIO - Svanhovd Norwegian Institute of Bioeconomy Research Svanvik Norway.

Large terrestrial carnivores can sometimes display strong family bonds affecting the spatial distribution of related individuals. We studied the spatial genetic relatedness and family structure of female Eurasian lynx, continuously distributed in southern Finland. We hypothesized that closely related females form matrilineal assemblages, clustering together with relatives living in the neighboring areas. Read More

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November 2018

Endogenous toxins and the coupling of gregariousness to conspicuousness in Argidae and Pergidae sawflies.

Sci Rep 2018 Dec 5;8(1):17636. Epub 2018 Dec 5.

SNSB - Zoologische Staatssammlung München, Münchhausenstr. 21, 81247, Munich, Germany.

Phytophagous insects tend to be either cryptic and solitary, or brightly colored and gregarious, as a defense against vertebrate predators. Here, we tested whether potent defensive chemicals produced de novo by larvae of Argidae and Pergidae sawflies have influenced the evolutionary relationship between larval appearance and levels of gregariousness. Phylogeny-based correlation analyses indicated only a weak trend for solitary species to be cryptic, and for gregarious ones to be conspicuous. Read More

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December 2018

Pesticide Exposure Assessment Paradigm for Solitary Bees.

Environ Entomol 2018 Dec 3. Epub 2018 Dec 3.

Centre for Ecological Research and Forestry Applications, CREAF, Edifici C, Campus UAB, Bellaterra, Spain.

Current pesticide risk assessment for bees relies on a single (social) species, the western honey bee, Apis mellifera L. (Hymenoptera: Apidae). However, most of the >20,000 bee species worldwide are solitary. Read More

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December 2018

Assessing Cellular Stress and Inflammation in Discrete Oxytocin-secreting Brain Nuclei in the Neonatal Rat Before and After First Colostrum Feeding.

J Vis Exp 2018 Nov 14(141). Epub 2018 Nov 14.

Department of Psychiatry, Columbia University; Department of Pathology & Cell Biology, Columbia University Medical Center;

The goal of this protocol is to isolate oxytocin-receptor rich brain nuclei in the neonatal brain before and after first colostrum feeding. The expression of proteins known to respond to metabolic stress was measured in brain-nuclei isolates using Western blotting. This was done to assess whether metabolic stress-induced nutrient insufficiency in the body triggered neuronal stress. Read More

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November 2018

The role of bitter and sweet taste receptors in upper airway innate immunity: Recent advances and future directions.

World J Otorhinolaryngol Head Neck Surg 2018 Sep 24;4(3):200-208. Epub 2018 Aug 24.

Department of Otorhinolaryngology-Head and Neck Surgery, Division of Rhinology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.

Bitter (T2R) and sweet (T1R) taste receptors have been implicated in sinonasal innate immunity and in the pathophysiology of chronic rhinosinusitis (CRS). Taste receptors are expressed on several sinonasal cell types including ciliated epithelial cells and solitary chemosensory cells. Bitter agonists released by pathogenic microbes elicit a T2R dependent signaling cascade which induces the release of bactericidal nitric oxide, increases mucociliary clearance, and promotes secretion of antimicrobial peptides. Read More

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September 2018

Validation of the OncoHepa test, a multigene expression profile test, and the tumor marker-volume score to predict postresection outcome in small solitary hepatocellular carcinomas.

Ann Surg Treat Res 2018 Dec 26;95(6):303-311. Epub 2018 Nov 26.

Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Purpose: OncoHepa test is a multigene expression profile test developed for assessment of hepatocellular carcinoma (HCC) prognosis. Multiplication of α-FP, des-γ-carboxy prothrombin (DCP) and tumor volume (TV) gives the α-FP-DCP-volume (ADV) score, which is also developed for assessment of HCC prognosis.

Methods: The predictive powers of OncoHepa test and ADV score were validated in 35 patients who underwent curative hepatic resection for naïve solitary HCCs ≤5 cm. Read More

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December 2018

Band adhesions not related to previous abdominal surgery - A retrospective cohort analysis of risk factors.

Ann Med Surg (Lond) 2018 Dec 13;36:185-190. Epub 2018 Nov 13.

Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sweden.

Background: Postoperative intra-abdominal adhesion formation is a common cause of small bowel obstruction (SBO). Adhesions causing SBO are classed as either matted adhesions or solitary band adhesions. The aim of this study was to investigate the prevalence of previous abdominal surgery in a cohort of patients operated for bowel obstruction and to analyze the causes of obstruction discovered at surgery. Read More

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December 2018

Safety of selective nonoperative management for blunt splenic trauma: the impact of concomitant injuries.

Patient Saf Surg 2018 27;12:32. Epub 2018 Nov 27.

1Department of Trauma, University Medical Centre Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.

Background: Nonoperative management for blunt splenic injury is the preferred treatment. To improve the outcome of selective nonoperative therapy, the current challenge is to identify factors that predict failure. Little is known about the impact of concomitant injury on outcome. Read More

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November 2018

A rare case of solitary unifocal Langerhans cell histiocytosis with orbital extension: Diagnostic dilemma.

Oman J Ophthalmol 2018 Sep-Dec;11(3):284-287

Department of Ophthalmology, University of Malaya Medical Centre, Kuala Lumpur, Malaysia.

Langerhans cell histiocytosis (LCH) is rarely encountered in ophthalmology practice. It is a spectrum of disorder characterized by accumulation of histiocytes in various tissues. Diagnosis is challenging as it may simulate periorbital hematoma, rhabdomyosarcoma, and neuroblastoma. Read More

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December 2018

Epidermotropism in Nodular Secondary Syphilis.

Indian J Dermatol 2018 Nov-Dec;63(6):509-511

Department of Dermatology, Consorcio Hospital General Universitario de Valencia, Valencia, Spain.

Nodular secondary syphilis results from the hematogenous and lymphatic dissemination of spirochetes. Clinically, the lesions appear as partially infiltrated plaques or red-violaceous nodules, which can be solitary or multiple. Several hypotheses have been put forward to explain the formation of these infiltrated or granulomatous lesions. Read More

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December 2018

Acral and Multicentric Pigmented Bowen's Disease in HIV-Positive Patients: Report on Two Unusual Cases.

Indian J Dermatol 2018 Nov-Dec;63(6):506-508

Centro De Investigación En Enfermedades Infecciosas, Instituto Nacional De Enfermedades Respiratorias, Ismael Cosío Villegas, México City, México.

squamous cell carcinoma of the skin (SCCis or Bowen's disease) is a common intraepidermal cutaneous malignancy with a low invasive potential. Acral Bowen's disease is usually solitary, but multiple acral SCCis have been reported. Pigmented Bowen's disease is typically unilesional and characterized by a hyperpigmented plaque with a velvety of keratotic surface, which can eventually simulate melanoma clinically. Read More

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December 2018

Novel insights and therapeutic approaches in idiopathic multicentric Castleman disease.

Hematology Am Soc Hematol Educ Program 2018 Nov;2018(1):318-325

Division of Translational Medicine & Human Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

Castleman disease (CD) describes a heterogeneous group of hematologic disorders that share characteristic lymph node histopathology. Patients of all ages present with either a solitary enlarged lymph node (unicentric CD) or multicentric lymphadenopathy (MCD) with systemic inflammation, cytopenias, and life-threatening multiple organ dysfunction resulting from a cytokine storm often driven by interleukin 6 (IL-6). Uncontrolled human herpesvirus-8 (HHV-8) infection causes approximately 50% of MCD cases, whereas the etiology is unknown in the remaining HHV-8-negative/idiopathic MCD cases (iMCD). Read More

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November 2018

Intraspinal Dissemination and Local Recurrence of an Intracranial Hemangiopericytoma: Case Report.

World Neurosurg 2018 Nov 29. Epub 2018 Nov 29.

Department of Neurosurgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Background: Hemangiopericytomas (HPCs) are rare vascular tumors that resemble meningiomas on imaging and have a high rate of local recurrence and metastases. There remains a paucity of data to guide management decisions of intraspinal dissemination of HPC in the literature, and none specifically related to anaplastic HPCs.

Case Description: Case report of a 34-year-old female with locally and distantly recurrent anaplastic hemangiopericytoma (HPC) (WHO grade III). Read More

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November 2018

Demodulated standing solitary wave and DNA-RNA transcription.

Chaos 2018 Nov;28(11):113103

Joint Institute for Nuclear Research, Joliot-Curie 6, 141980 Dubna, Moscow Region, Russia.

Nonlinear dynamics of DNA molecule at segments where DNA-RNA transcription occurs is studied. Our basic idea is that the solitary wave, moving along the chain, transforms into a demodulated one at these segments. The second idea is that the wave becomes a standing one due to interaction with DNA surrounding, e. Read More

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November 2018

Dynamics of a modified excitable neuron model: Diffusive instabilities and traveling wave solutions.

Chaos 2018 Nov;28(11):113104

Department of Applied Mathematics, Indian Institute of Technology (Indian School of Mines), Dhanbad 826004, India.

We examine the dynamics of a spatially extended excitable neuron model between phase state and stable/unstable equilibrium point depending on the parameter regimes. The solitary wave profiles in the excitable medium are characterized by an improved Hindmarsh-Rose (H-R) spiking-bursting neuron model with an injected decaying current function. Linear stability and the nature of deterministic system dynamics are analyzed. Read More

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November 2018

Percutaneous laser ablation of benign thyroid nodules: a one year follow-up study.

Einstein (Sao Paulo) 2018 Nov 29;16(4):eAO4279. Epub 2018 Nov 29.

Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.

Objective: To evaluate safety and effectiveness of nodule volume reduction and thyroid function after percutaneous laser ablation treatment in patients with benign nonfunctioning thyroid nodules.

Methods: Prospective single-center study, from January 2011 to October 2012, which evaluated 30 euthyroid and thyroid antibodies negative patients with benign solitary or dominant nodule with indication of treatment due to compressive symptoms and aesthetic disturbances. The clinical and laboratory (thyroid ultrasound, TSH, FT4, TG, TG-Ab, TPO-Ab and TRAb levels) evaluations were performed before the procedure, and periodically 1 week, 3 months and 6 months after. Read More

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November 2018
1 Read

Pulmonary high-resolution computed tomography findings in patients with synovitis, acne, pustulosis, hyperostosis and osteitis syndrome.

PLoS One 2018 5;13(12):e0206858. Epub 2018 Dec 5.

Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

Objective: To characterize the high-resolution computed tomography (HRCT) pulmonary abnormalities in patients with synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome.

Methods: Pulmonary HRCT images were reconstructed from whole-spine computed tomography (CT) images of 67 patients with SAPHO syndrome. HRCT images of 58 healthy controls were also obtained and reviewed. Read More

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December 2018

Single Rooms, Seclusion and the Non-Restraint Movement in British Asylums, 1838-1844.

Authors:
Leslie Topp

Soc Hist Med 2018 Nov 14;31(4):754-773. Epub 2018 Mar 14.

Birkbeck, University of London, Reader in History of Architecture, London, UK.

This article shows how the practice of seclusion-the confinement of asylum patients in locked rooms alone-entered the spotlight during the bitter controversy over the abolition of mechanical restraints in the late 1830s and early 1840s. Drawing on letters to , asylum reports, reports of the Commissioners in Lunacy and polemical pamphlets, and focusing on the two asylums at the centre of the controversy, Lincoln and Hanwell, the article sets out the range of positions taken, from pro-restraint and anti-seclusion to anti-restraint and pro-seclusion. It shows how seclusion was associated with a lack of transparency, how it was seen as parallel to the disputed practice of solitary confinement in the prison system and how both the practice of seclusion and the single room itself were modified in the face of these challenges. Read More

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November 2018

Le score échographique EU-TIRADS permet de prédire le risque de carcinome.

Authors:
Gilles Russ

Rev Prat 2017 Jun;67(6):663-668

Centre de pathologie et d'imagerie, Paris, France, unité thyroïde et tumeurs endocrines (Pr Leenhardt), groupe hospitalier La Pitié-Salpêtrière, UPMC université Paris-VI, Paris, France.

Management of thyroid nodules. Thyroid nodules are frequent and most of them are benign incidentalomas. Physical examination will search for risk factors of thyroid cancer and should evaluate the presence of local or cosmetic symptoms. Read More

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Solitary fibrous tumor of central nervous system masquerading as meninigioma: Report of a rare case.

Int J Surg Case Rep 2018 Nov 27;54:10-14. Epub 2018 Nov 27.

Deptt. of Pathology, PGIMS Rohtak, Haryana, India. Electronic address:

Introduction: Solitary fibrous tumor (SFT) is a rare neoplasm of mesenchymal origin that occurs most often in the visceral pleura. It rarely occurs in the central nervous system (CNS). If they occur intracranially, they are extra-axially located and develop from the meninges. Read More

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November 2018

Solitary Bone Metastasis as the First Presentation of Germ Cell Testicular Cancer Treated with Internal Hemipelvectomy: A Case Report.

Urol Int 2018 Dec 4:1-4. Epub 2018 Dec 4.

Department of Pelvic Surgery, A.C. Camargo Cancer Center, São Paulo, Brazil.

Solitary bone metastasis from testicular tumor is rare. In literature, only few cases of isolated bone metastasis at first presentation have been reported, and none of them have been treated with extended surgery of the pelvic bone. Case Presentation: We report the case of a 33-year-old man with an iliac bone osteolytic metastasis as the first presentation of a non-seminomatous germ-cell testis tumor (NSGCT), treated with post-chemotherapy en bloc resection of residual tumor in the left iliac bone (Type I + II internal hemipelvectomy). Read More

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December 2018
2 Reads

Colonic metastasis from infiltrating ductal breast carcinoma in a male patient: A case report.

Int J Surg Case Rep 2018 Nov 16;54:34-38. Epub 2018 Nov 16.

Department of Surgery, Palmetto Healthcare System, University of South Carolina Medical School, 2 Medical Park Road, Columbia, SC 29203, United States. Electronic address:

Introduction: A colonic metastasis from infiltrating breast ductal carcinoma is a rare phenomenon in the literature, especially in a male.

Presentation Of Case: We present a rare case of a 55-year-old male with a past medical history of breast cancer who presented with signs and symptoms of appendicitis. A computed tomography (CT) scan revealed acute appendicitis in addition to a 2. Read More

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November 2018
5 Reads

Adrenalectomy for solitary recurrent hepatocellular carcinoma five years after living donor liver transplantation: A case report.

Int J Surg Case Rep 2018 Nov 27;54:23-27. Epub 2018 Nov 27.

Diagnostic & Interventional Radiology Department, Gastrointestinal Surgery Center, College of Medicine, Mansoura University, Egypt.

Introduction: The adrenal gland is a rare site for hepatocellular carcinoma (HCC) recurrence after living-donor liver transplantation (LDLT). Solitary adrenal recurrence can be managed by surgical excision, with expected better survival outcomes. We describe a rare case of successful left adrenalectomy of solitary recurrent HCC in the left adrenal gland 5 years after LDLT. Read More

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November 2018
1 Read

Management of Fat Necrosis after Autologous Fat Transplantation for Breast Augmentation.

Plast Reconstr Surg 2018 Nov;142(5):665e-673e

Taipei, Taiwan; and Sacramento, Calif. From the Division of Plastic Surgery, Department of Surgery, Taipei Medical University Hospital, Taipei Medical University; and the Division of Plastic Surgery, Department of Surgery, University of California, Davis Medical Center.

Background: Palpable lumps as sequelae of fat necrosis after fat grafting to the breast may not only cause physical or psychological symptoms to patients but also potentially complicate breast cancer screening. In this article, the authors present their experience in management of fat necrosis following fat grafting for breast augmentation.

Methods: Over a 5-year period, a total of 685 Asian women (age range, 20 to 58 years) underwent autologous fat transplantation to the breasts. Read More

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November 2018
3 Reads

Solitary rectal ulcer syndrome complicating sessile serrated adenoma/polyps: A case report and review of literature.

World J Clin Cases 2018 Nov;6(14):820-824

Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai 200032, China.

Solitary rectal ulcer syndrome (SRUS) is a rare benign condition, which can mimic many other diseases because of their similarities in clinical, endoscopic and histological features. Sessile serrated adenoma/polyp (SSA/p) is a premalignant lesion in the colon and rectum. The misdiagnosis of SSA/p in SRUS patients has been noted, but the case of SRUS arising secondarily to SSA/p has been rarely reported. Read More

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November 2018
1 Read

Solitary Lytic Bone Metastasis: A Rare Presentation of Small Lymphocytic Leukemia.

Case Rep Hematol 2018 30;2018:6154709. Epub 2018 Oct 30.

Department of Hematology/Oncology, Joan C. Edwards School of Medicine Marshall University, 1600 Medical Center Dr, Huntington, WV 25701, USA.

Chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) is a hematologic malignancy characterized by an over accumulation of incompetent neoplastic lymphocytes. Bone metastasis in CLL/SLL is very rare. We report a case of a 76-year-old Caucasian female presented with an unresolving pulmonary infiltrate with mediastinal lymphadenopathy concerning for malignancy. Read More

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October 2018
1 Read

Detection of Individual Prostate Cancer Foci via Multiparametric Magnetic Resonance Imaging.

Eur Urol 2018 Nov 30. Epub 2018 Nov 30.

Department of Urology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA. Electronic address:

Background: Multiparametric magnetic resonance imaging (mpMRI) undoubtedly affects the diagnosis and treatment of localized prostate cancer (CaP). However, clinicians need a better understanding of its accuracy and limitations in detecting individual CaP foci to optimize management.

Objective: To determine the per-lesion detection rate for CaP foci by mpMRI and identify predictors of tumor detection. Read More

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November 2018
1 Read

Superficial femoral venous aneurysm in a patient with Klippel-Trenaunay Syndrome: the inguinal hernia mimic.

Ann Vasc Surg 2018 Nov 27. Epub 2018 Nov 27.

Department of Vascular Surgery, Waikato District Health Board, Hamilton, New Zealand.

Venous aneurysms are a rare vascular anomaly characterised by a solitary area of dilatation containing all three layers of the venous vessel wall. Described throughout the venous system, venous aneurysms can be classified as deep or superficial based on the vein involved. Whilst generally asymptomatic, superficial venous aneurysms can be associated with venous insufficiency or venous thromboembolism and are often confused for soft tissue masses or hernias. Read More

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November 2018
3 Reads

Solitary fibrous tumor/hemangiopericytoma of the optic canal.

Clin Neuropathol 2018 Nov 30. Epub 2018 Nov 30.

Solitary fibrous tumor/hemangiopericytoma seldom arises from the optic nerve sheath. Herein, we describe the clinical, radiological, and histological findings of a solitary fibrous tumor/hemangiopericytoma arising from the optic nerve sheath and occupying the optic canal. The diagnosis is challenging both clinically and histologically as it clinically simulates a commoner lesion, i. Read More

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November 2018

Impact of follow-up interval on patients with hepatocellular carcinoma after curative ablation.

BMC Cancer 2018 Nov 29;18(1):1186. Epub 2018 Nov 29.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China.

Background: The optimal follow-up strategy after curative thermal ablation of hepatocellular carcinoma (HCC) remains unclear.

Methods: We retrospectively analyzed a prospective series of 616 patients who underwent curative thermal ablation for HCC within the Milan criteria. Multivariate Cox model was used to identify independent predictive factors for recurrence; accordingly, patients were stratified into 2 groups with different relapse risks: a low-risk group (solitary tumor ≤3 cm) and a high-risk group (multiple tumors ≤3 cm or solitary tumor between 3 and 5 cm). Read More

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November 2018

Primary Diffuse Leptomeningeal Melanomatosis: Case Report and Review of the Literature.

World Neurosurg 2018 Nov 26. Epub 2018 Nov 26.

Phil Smith Neuroscience Institute, Holy Cross Hospital, Fort Lauderdale, Florida, 33308, USA.

Background: Primary diffuse leptomeningeal melanomatosis (PDLM) is an extremely rare pathologic condition that can mimic several other neurologic disease states.

Methods: We report a rare case of PDLM without evidence of a primary focus. Additionally, we performed a comprehensive review of the literature to describe all previously reported cases of PDLM. Read More

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November 2018

Dual pathways in social evolution: Population genetic structure of group-living and solitary species of kleptoparasitic spiders (Argyrodinae: Theridiidae).

PLoS One 2018 29;13(11):e0208123. Epub 2018 Nov 29.

Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, Kansas, United States of America.

Group-living behavior is taxonomically widespread but rare in spiders. The conventional view is that the main pathways to group-living in spiders are either sub-social, where extended maternal care leads to prolonged sibling association; or communal living, where individuals aggregate to exploit a common resource. Female egg-sac guarding behavior occurs throughout kleptoparasitic spiders in the subfamily Argyrodinae (Theridiidae), while individuals in group-living species cohabit in the resource rich webs of their host spiders. Read More

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November 2018

Concomitant fibrofolliculoma and trichodiscoma on the abdomen.

Cutis 2018 Oct;102(4):E30-E32

Department of Dermatology, Harbor-UCLA Medical Center, Torrance, California, USA.

Fibrofolliculoma and trichodiscoma are adnexal tumors that arise from or around hair follicles and are two of the many characteristic features of Birt-Hogg-Dubé (BHD) syndrome. Fibrofolliculoma and other hair follicle hamartomas can be differentiated from their clinically indistinct counterparts (eg, trichodiscomas, trichoadenomas) by histologic and staining comparison. We report a rare case of a 54-year-old man who presented with a subcutaneous papule on the abdomen that was histologically proven to have features of both a solitary fibrofolliculoma and trichodiscoma. Read More

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October 2018

Solitary exophytic plaque on the left groin.

Cutis 2018 Oct;102(4):E15-E17

Department of Dermatology, Istanbul Medeniyet University Goztepe Research and Training Hospital, Turkey.

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October 2018

RETINAL CAPILLARY MACROANEURYSMS.

Retina 2018 Nov 21. Epub 2018 Nov 21.

Department of Ophthalmology, Hospital Universitari de Bellvitge, Barcelona, Spain.

Purpose: To investigate eyes with solitary large aneurysms arising from retinal capillaries.

Methods: Consecutive patients with aneurysms greater than 200 µm in diameter were evaluated with a comprehensive ophthalmologic examination including optical coherence tomography, optical coherence tomography angiography, and fluorescein angiography. The aneurysms were solitary in the sense, and there was only one aneurysm larger than the threshold diameter and a few or no other aneurysms. Read More

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November 2018

Development and organization of the secondary and tertiary lymphoid organs: Influence of microbial and food antigens.

Endocr Metab Immune Disord Drug Targets 2018 Nov 28. Epub 2018 Nov 28.

Department of Basic Medical Sciences, Neuroscience and Sensory Organs, University of Bari, School of Medicine, Bari. Italy.

Background: Secondary lymphoid organs (SLO) are distributed in many districts of the body and, especially, lymph nodes, spleen and gut-associated lymphoid tissue are the main cellular sites. On the other hand, tertiary lymphoid organs (TLO) are formed in response to inflammatory, infectious, autoimmune and neoplastic events. Developmental studies: In the present review, emphasis will be placed on the developmental differences of SLO and TLO between small intestine and colon and on the role played by various chemokines and cell receptors. Read More

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November 2018

Histogram analysis of amide proton transfer-weighted imaging: comparison of glioblastoma and solitary brain metastasis in enhancing tumors and peritumoral regions.

Eur Radiol 2018 Nov 28. Epub 2018 Nov 28.

Department of Radiology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan.

Objectives: Differentiation of glioblastomas (GBMs) and solitary brain metastases (SBMs) is an important clinical problem. The aim of this study was to determine whether amide proton transfer-weighted (APTW) imaging is useful for distinguishing GBMs from SBMs.

Methods: We examined 31 patients with GBM and 17 with SBM. Read More

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November 2018

Novel insights and therapeutic approaches in idiopathic multicentric Castleman disease.

Blood 2018 Nov;132(22):2323-2330

Division of Translational Medicine & Human Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

Castleman disease (CD) describes a heterogeneous group of hematologic disorders that share characteristic lymph node histopathology. Patients of all ages present with either a solitary enlarged lymph node (unicentric CD) or multicentric lymphadenopathy (MCD) with systemic inflammation, cytopenias, and life-threatening multiple organ dysfunction resulting from a cytokine storm often driven by interleukin 6 (IL-6). Uncontrolled human herpesvirus-8 (HHV-8) infection causes approximately 50% of MCD cases, whereas the etiology is unknown in the remaining HHV-8-negative/idiopathic MCD cases (iMCD). Read More

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November 2018

Pediatric intramedullary schwannoma with syringomyelia: a case report and literature review.

BMC Pediatr 2018 Nov 28;18(1):374. Epub 2018 Nov 28.

Department of Neurosurgery, Beijing Jishuitan Hospital, NO31, Xinjiekou East Street, Xicheng District, Beijing, 100035, China.

Background: Intramedullary schwannomas without neurofibromatosis are exceedingly rare. They are rarer in children with only 8 cases reported so far. The association of intramedullary schwannomas with syringomyelia is also rare. Read More

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November 2018

BOLD fMRI effects of transcutaneous vagus nerve stimulation in patients with chronic tinnitus.

PLoS One 2018 28;13(11):e0207281. Epub 2018 Nov 28.

Neuroscience Research Institute, Kangwon National University Hospital, Chuncheon, Republic of Korea.

Objective: Vagus nerve stimulation (VNS) is a neuromodulation method used for treatment of epilepsy and depression. Transcutaneous VNS (tVNS) has been gaining popularity as a noninvasive alternative to VNS. Previous tVNS neuroimaging studies revealed brain (de)activation patterns that involved multiple areas implicated in tinnitus generation and perception. Read More

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November 2018

Validation of the MAGGIC (Meta-Analysis Global Group in Chronic Heart Failure) heart failure risk score and the effect of adding natriuretic peptide for predicting mortality after discharge in hospitalized patients with heart failure.

PLoS One 2018 28;13(11):e0206380. Epub 2018 Nov 28.

Department of Cardiology, Wonju College of Medicine, Yonsei University, Wonju, Republic of Korea.

Background: In clinical practice, a risk prediction model is an effective solitary program to predict prognosis in particular patient groups. B-type natriuretic peptide (BNP)and N-terminal pro-b-type natriuretic peptide (NT-proBNP) are widely recognized outcome-predicting factors for patients with heart failure (HF).This study derived external validation of a risk score to predict 1-year mortality after discharge in hospitalized patients with HF using the Meta-analysis Global Group in Chronic Heart Failure (MAGGIC)program data. Read More

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November 2018

Solitary colorectal liver metastasis after curative intent surgery: prognostic factors affecting outcomes and survival.

ANZ J Surg 2018 Nov 28. Epub 2018 Nov 28.

Department of Surgery, University of Ulsan College of Medicine, Institute of Innovative Cancer Research, and Asan Medical Center, Seoul, South Korea.

Background: The aim of this study was to identify the prognostic factors affecting recurrence and survival in patients who underwent curative intent surgery for colorectal cancer (CRC) with a single liver metastasis.

Methods: Between January 2006 and August 2012, we retrospectively evaluated 141 patients for CRC with single liver metastasis underwent curative intent surgery for colon and liver simultaneously. Some patients (11. Read More

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November 2018