5,479 results match your criteria Solitary Pulmonary Nodule

Efficient multiscale fully convolutional UNet model for segmentation of 3D lung nodule from CT image.

J Med Imaging (Bellingham) 2022 Sep 11;9(5):052402. Epub 2022 May 11.

Karunya Institute of Technology and Sciences, Department of Computer Science and Engineering, Coimbatore, Tamil Nadu, India.

Segmentation of lung nodules in chest CT images is essential for image-driven lung cancer diagnosis and follow-up treatment planning. Manual segmentation of lung nodules is subjective because the approach depends on the knowledge and experience of the specialist. We proposed a multiscale fully convolutional three-dimensional UNet (MF-3D UNet) model for automatic segmentation of lung nodules in CT images. Read More

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September 2022

Pulmonary arteriovenous malformation and inherent complications with solitary lung nodule biopsy-literature overview and case report.

Radiol Case Rep 2022 Jul 6;17(7):2353-2361. Epub 2022 May 6.

Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.

Pulmonary arteriovenous malformation, also known as an arteriovenous fistula, is typically a congenital disease caused by structural deficiencies, particularly the lack of capillary wall development, leading to the abnormal dilation of the pulmonary capillaries. The majority of pulmonary arteriovenous malformation cases are associated with Rendu-Osler-Weber syndrome, also known as hereditary hemorrhagic telangiectasia. Pulmonary arteriovenous malformation rarely occurs due to chest trauma. Read More

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The role of computer-assisted radiographer reporting in lung cancer screening programmes.

Eur Radiol 2022 May 14. Epub 2022 May 14.

Lungs for Living Research Centre, UCL Respiratory, Rayne Institute, University College London, 5 University Street, London, WC1E 6JF, UK.

Objectives: Successful lung cancer screening delivery requires sensitive, timely reporting of low-dose computed tomography (LDCT) scans, placing a demand on radiology resources. Trained non-radiologist readers and computer-assisted detection (CADe) software may offer strategies to optimise the use of radiology resources without loss of sensitivity. This report examines the accuracy of trained reporting radiographers using CADe support to report LDCT scans performed as part of the Lung Screen Uptake Trial (LSUT). Read More

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The risk factors for the failure of hook wire localization of ground glass nodules prior to thoracoscopic surgery.

J Cardiothorac Surg 2022 May 11;17(1):114. Epub 2022 May 11.

Graduate School, Tianjin Medical University, Tianjin, 300070, People's Republic of China.

Objectives: To retrospectively analyse the potential influencing factors of CT-guided hook wire localization failure prior to thoracoscopic resection surgery of ground glass nodules (GGNs), and determine the main risk elements for localization failure.

Methods: In all, 372 patients were included in this study, with 21 patients showing localization failure. The related parameters of patients, GGNs, and localization were analysed through univariate and multiple logistic regression analysis to determine the risk factors of localization failure. Read More

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Validation of a deep learning computer aided system for CT based lung nodule detection, classification, and growth rate estimation in a routine clinical population.

PLoS One 2022 5;17(5):e0266799. Epub 2022 May 5.

Department of Radiology, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.

Objective: In this study, we evaluated a commercially available computer assisted diagnosis system (CAD). The deep learning algorithm of the CAD was trained with a lung cancer screening cohort and developed for detection, classification, quantification, and growth of actionable pulmonary nodules on chest CT scans. Here, we evaluated the CAD in a retrospective cohort of a routine clinical population. Read More

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Predictive model for the probability of malignancy in solitary pulmonary nodules: a meta-analysis.

J Cardiothorac Surg 2022 May 3;17(1):102. Epub 2022 May 3.

Department of Radiology, Xuzhou Central Hospital, Xuzhou, China.

Background: To date, multiple predictive models have been developed with the goal of reliably differentiating between solitary pulmonary nodules (SPNs) that are malignant and those that are benign. The present meta-analysis was conducted to assess the diagnostic utility of these predictive models in the context of SPN differential diagnosis.

Methods: The PubMed, Embase, Cochrane Library, CNKI, Wanfang, and VIP databases were searched for relevant studies published through August 31, 2021. Read More

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Classification and Segmentation Algorithm in Benign and Malignant Pulmonary Nodules under Different CT Reconstruction.

Comput Math Methods Med 2022 21;2022:3490463. Epub 2022 Apr 21.

Cancer Center, Department of Radiology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou 310014, China.

Methods: The imaging data of 55 patients with chest CT plain scan in the Xuancheng People's Hospital were collected retrospectively. The data of each patient included lung window reconstruction, mediastinum reconstruction, and bone window reconstruction. The depth neural network and 3D convolution neural network were used to construct the model and train the classification and segmentation algorithm. Read More

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[Application value of combined deep inhalation and breath-hold technique guided by four-dimensional CT in preoperative localization of solitary pulmonary nodules].

Zhonghua Yi Xue Za Zhi 2022 May;102(17):1278-1282

Department of Oncology and Chemoradiotherapy, Ningbo First Hospital, Ningbo 315000, China.

To explore the clinical value of four dimensional computed tomography (4 D CT) guided combined with deep inhalation and breath hold (DIBH) technique in the preoperative localization of solitary pulmonary nodules. The data of a total of 106 patients with solitary pulmonary nodules from March 2018 to May 2021 in the Ningbo First Hospital were collected retrospectively. Among them, there were 26 males and 80 females aged from 21 to 83 (47. Read More

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The reporting of pulmonary nodule results by letter in a lung cancer screening setting.

Lung Cancer 2022 Apr 20;168:46-49. Epub 2022 Apr 20.

Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK. Electronic address:

Objectives: Pulmonary nodules are commonly found in Lung Cancer Screening (LCS), with results typically communicated by face-to-face or telephone consultation. Providing LCS on a population basis requires resource efficient and scalabe communication methods. Written communication provides one such method. Read More

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An 18F-FDG-PET-Positive Mucoid Impaction With Ring Enhancement on CT Mimicking Lung Cancer.

Clin Nucl Med 2022 Apr 29. Epub 2022 Apr 29.

Department of Community Medicine for Respirology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan.

Abstract: We encountered a case of an 18F-FDG PET-positive solitary nodule with ring enhancement on CT mimicking lung cancer in the left S6 region of an 80-year-old woman. Since transbronchial biopsy by endobronchial ultrasonography with a guide sheath could not obtain sufficient material, despite the guide sheath being placed within the lesion, the patient underwent thoracoscopic partial left S6 resection. The nodule was diagnosed as acquired cystic bronchiectasis and mucoid impaction associated with chronic inflammation. Read More

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Predictors of malignancy in patients with solitary pulmonary nodules undergoing pulmonary resection.

Clin Respir J 2022 Apr 26. Epub 2022 Apr 26.

Department of Cardiovascular and Thoracic Surgery, West Virginia University Heart and Vascular Institute, Morgantown, West Virginia, USA.

Background: The management of a solitary pulmonary nodule is a challenging issue in pulmonary disease. Although many factors have been defined as predictors for malignancy in solitary pulmonary nodules, the accurate diagnosis can only be established with the permanent histological diagnosis.

Objective: We tried to clarify the possible predictors of malignancy in solitary pulmonary nodules in patients who had definitive histological diagnosis. Read More

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Imaging Characteristics and Prognostic Value of Isolated Pulmonary Metastasis from Colorectal Cancer Demonstrated withF-FDG PET/CT.

Biomed Res Int 2022 14;2022:2230079. Epub 2022 Apr 14.

Department of Nuclear Medicine, Changshu No. 2 People's Hospital, Changshu, China.

Objective: Solitary pulmonary lesions (SPNs) in patients with a history of colorectal cancer (CRC) may be attributed to metastatic lung tumors, primary lung cancer, or benign nodules. We aimed to analyze the imaging characteristics of SPNs in CRC patients to differentiate these pulmonary nodules and evaluate the prognostic value of isolated pulmonary metastasis from CRC using F-FDG PET/CT.

Methods: From January 2013 to January 2021, 62 CRC patients with SPNs demonstrated with F-FDG PET/CT were retrospectively enrolled in the present study. Read More

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Safety and Efficacy of Cone-Beam Computed Tomography-Guided Lung Tumor Localization with a Near-Infrared Marker: A Retrospective Study of 175 Patients.

Life (Basel) 2022 Mar 28;12(4). Epub 2022 Mar 28.

Division of Thoracic Surgery, Chang Gung Memorial Hospital-Linkou, Chang Gung University, Taoyuan 333423, Taiwan.

Preoperative localization holds promise for overcoming the limitations of video-assisted thoracoscopic surgery (VATS) in the treatment of impalpable lung nodules. The purpose of this study was to assess the safety and efficacy of cone-beam computed tomography (CBCT)-guided localization using near-infrared (NIR) marking. Between 2017 and 2021, patients presenting with a solitary pulmonary nodule (SPN) who had undergone CBCT-guided lesion localization with indocyanine green (ICG) in a hybrid operating room were included. Read More

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Pulmonary inflammatory myofibroblastic tumor coexisting with lymphangitis carcinomatosis: Mimicking metastatic papillary thyroid carcinoma with nodular fasciitis-like stroma.

Indian J Pathol Microbiol 2022 Apr-Jun;65(2):422-425

Department of Surgical Pathology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, Maharashtra, India.

Inflammatory myofibroblastic tumors (IMTs) are uncommon; intermediate grade soft tissue tumors occurring in young individuals with an uncertain behaviour. The incidence of pulmonary lymphangitis carcinomatosis (PLC) is around 6-8% of all pulmonary metastases. However, PLC due to papillary thyroid carcinoma (PTC) is very uncommon. Read More

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Pulmonary nodule malignancy probability: a diagnostic accuracy meta-analysis of the Mayo model.

Clin Radiol 2022 Jun 11;77(6):443-450. Epub 2022 Apr 11.

Pulmonary and Respiratory Failure Department, First ICU, Evaggelismos Hospital, Athens, Greece; National and Kapodistrian University of Athens, Athens, Greece. Electronic address:

Aim: To quantify the overall diagnostic accuracy of the Mayo model in predicting the probability of malignancy of solitary pulmonary nodules (SPNs) by carrying out a systematic review and meta-analysis.

Materials And Methods: PubMed, Scopus, and references of relevant articles were searched systematically from inception up to 21 September 2021, to identify observational cohort studies, which reported on the diagnostic accuracy of the Mayo model in predicting the probability of malignancy in SPNs. The primary outcome was the pooled area under the receiver operating characteristic (ROC) curve (AUC). Read More

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Diagnostic value of circulating genetically abnormal cells to support computed tomography for benign and malignant pulmonary nodules.

BMC Cancer 2022 Apr 9;22(1):382. Epub 2022 Apr 9.

Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan Province, China.

Background: The accuracy of CT and tumour markers in screening lung cancer needs to be improved. Computer-aided diagnosis has been reported to effectively improve the diagnostic accuracy of imaging data, and recent studies have shown that circulating genetically abnormal cell (CAC) has the potential to become a novel marker of lung cancer. The purpose of this research is explore new ways of lung cancer screening. Read More

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Thermal ablation for pulmonary subsolid nodules: Which consensus guidelines? which future perspectives?

Roberto Iezzi

J Cancer Res Ther 2021 12;17(7):1593-1595

Fondazione Policlinico Universitario A. Gemelli IRCCS, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia - Istituto di Radiologia, l.go A gemelli 8, 00168; Università Cattolica del Sacro Cuore, ROMA, Italia.

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December 2021

Diagnostic Value of Artificial Intelligence Based on CT Image in Benign and Malignant Pulmonary Nodules.

J Oncol 2022 24;2022:5818423. Epub 2022 Mar 24.

Department of Radiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Science, Beijing, China.

Objective: To evaluate the diagnostic value of artificial intelligence-assisted CT imaging in benign and malignant pulmonary nodules.

Methods: The CT scan screening of pulmonary nodules from November 2018 to November 2020 was retrospectively collected. The diagnosis of pulmonary nodules and surgical treatment were performed. Read More

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Robotic Navigational Bronchoscopy Combined with Needle-Based Confocal Laser Endomicroscopy: Case Report of a Novel Approach to Diagnose Small Lung Nodules.

Respiration 2022 29;101(5):494-499. Epub 2022 Mar 29.

Department of Respiratory Medicine, Amsterdam UMC, Amsterdam, The Netherlands.

Lung cancer is the most commonly diagnosed cancer and the leading cause of cancer-related death. Advancements in navigational bronchoscopy have shown encouraging results but the diagnostic yield of small lung nodules by bronchoscopic techniques is still below that of transthoracic needle aspiration. The development of robotic bronchoscopy has demonstrated a significantly improved navigational success but the diagnostic yield is regularly limited by near-miss of the target nodule. Read More

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Development and Validation of a Preoperative CT-Based Nomogram to Differentiate Invasive from Non-Invasive Pulmonary Adenocarcinoma in Solitary Pulmonary Nodules.

Cancer Manag Res 2022 20;14:1195-1208. Epub 2022 Mar 20.

Department of Thoracic Surgery, Hebei General Hospital, Shijiazhuang, People's Republic of China.

Purpose: This study aimed to develop and validate a preoperative CT-based nomogram combined with clinical and radiological features for distinguishing invasive from non-invasive pulmonary adenocarcinoma.

Patients And Methods: A total of 167 patients with solitary pulmonary nodules and pathologically confirmed adenocarcinoma treated between January 2020 and December 2020 at Hebei General Hospital were retrospectively assessed. To evaluate the probability of invasive pulmonary adenocarcinoma, we developed three models, the multivariate logistic regression model, the stepwise logistic regression model, and the cross-validation model. Read More

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[Chinese Experts Consensus on Artificial Intelligence Assisted Management for 
Pulmonary Nodule (2022 Version)].


Zhongguo Fei Ai Za Zhi 2022 Apr 28;25(4):219-225. Epub 2022 Mar 28.

Low-dose computed tomography (CT) for lung cancer screening has been proven to reduce lung cancer deaths in the screening group compared with the control group. The increasing number of pulmonary nodules being detected by CT scans significantly increase the workload of the radiologists for scan interpretation. Artificial intelligence (AI) has the potential to increase the efficiency of pulmonary nodule discrimination and has been tested in preliminary studies for nodule management. Read More

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Robotic Assisted Bronchoscopy: The Ultimate Solution for Peripheral Pulmonary Nodules?

Respiration 2022 23;101(5):437-440. Epub 2022 Mar 23.

Technical Physician, Pulmonary Diseases, Radboudumc, Nijmegen, The Netherlands.

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Bronchoscopic approaches to sampling lung nodules: Aiming for the bulls eye.

Respirology 2022 May 21;27(5):325-327. Epub 2022 Mar 21.

Department of Respiratory Medicine, Royal Brompton Hospital, London, UK.

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The impact of cardiopulmonary hemodynamic factors in volumetry for pulmonary nodule management.

BMC Med Imaging 2022 03 18;22(1):49. Epub 2022 Mar 18.

Imaging Department, University of Manchester, Manchester, UK.

Background: The acceptance of coronary CT angiogram (CCTA) scans in the management of stable angina has led to an exponential increase in studies performed and reported incidental findings, including pulmonary nodules (PN). Using low-dose CT scans, volumetry tools are used in growth assessment and risk stratification of PN between 5 and 8 mm in diameter. Volumetry of PN could also benefit from the increased temporal resolution of CCTA scans, potentially expediting clinical decisions when an incidental PN is first detected on a CCTA scan, and allow for better resource management and planning in a Radiology department. Read More

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Dynamic contrast-enhanced CT compared with positron emission tomography CT to characterise solitary pulmonary nodules: the SPUtNIk diagnostic accuracy study and economic modelling.

Health Technol Assess 2022 03;26(17):1-180

Department of Radiology, Aberdeen Royal Hospitals NHS Trust, Aberdeen, UK.

Background: Current pathways recommend positron emission tomography-computerised tomography for the characterisation of solitary pulmonary nodules. Dynamic contrast-enhanced computerised tomography may be a more cost-effective approach.

Objectives: To determine the diagnostic performances of dynamic contrast-enhanced computerised tomography and positron emission tomography-computerised tomography in the NHS for solitary pulmonary nodules. Read More

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Development of a diagnostic model for malignant solitary pulmonary nodules based on radiomics features.

Ann Transl Med 2022 Feb;10(4):201

Department of Respiratory and Critical Care Medicine, General Hospital of the People's Liberation Army, Beijing, China.

Background: This study proposed a precise diagnostic model for malignant solitary pulmonary nodules (SPNs). This model can be used to identify objective and quantifiable image features and guide the clinical treatment strategy adopted for SPNs. This model will help clinicians optimize management strategies for SPN. Read More

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February 2022

Marking ground glass nodules with pulmonary nodules localization needle prior to video-assisted thoracoscopic surgery.

Eur Radiol 2022 Mar 10. Epub 2022 Mar 10.

Department of Radiology, China-Japan Friendship Hospital, Beijing, China.

Objectives: To evaluate the efficacy and safety of marking ground glass nodules (GGNs) with pulmonary nodules localization needle (PNLN) prior to video-assisted thoracoscopic surgery (VATS).

Materials And Methods: From June 2020 to February 2021, all patients with GGNs who received CT-guided localization using PNLN before VATS were enrolled. Clinical and imaging data were retrospectively analyzed. Read More

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Analysis of Clinical Characteristics, Treatment, and Prognostic Factors of 106 Breast Cancer Patients With Solitary Pulmonary Nodules.

Front Surg 2022 15;9:843913. Epub 2022 Feb 15.

Key Laboratory of Cancer Prevention and Therapy, Department of Breast Cancer, National Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.

Objective: The clinical features of solitary pulmonary nodules (SPN) in breast cancer patients were retrospectively analyzed, and the clinical features of primary lung cancer (PLC) and metastatic pulmonary breast cancer (MBC) in breast cancer patients were compared, and the treatment plan, curative effect and influencing factors were analyzed.

Methods: The clinical data of 106 patients of SPN combined with breast cancer surgery in our hospital from January 2015 to June 2020 were analyzed. There were 65 patients of PLC and 41 patients of MBC. Read More

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February 2022

[67/m-Incidental finding of a solitary pulmonary nodule : Preparation for the medical specialist examination: part 145].

Internist (Berl) 2022 04 3;63(Suppl 2):259-263. Epub 2022 Mar 3.

Klinik für Radiologie, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland.

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Rare case of a synchronous pleural solitary fibrous tumour and a thymic cyst.

BMJ Case Rep 2022 Mar 1;15(3). Epub 2022 Mar 1.

Medicine, Mater Dei Hospital, Msida, Malta.

We present a unique case of a 41-year-old man with an anterior mediastinal mass and a pulmonary nodule, found incidentally on a thoracic CT. Further evaluation with an MRI revealed a thymic cyst which was multiloculated with several septations. Biopsy of the pulmonary nodule was performed and histology was consistent with a solitary fibrous tumour (SFT), on the benign spectrum. Read More

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