4,542 results match your criteria Solitary Pulmonary Nodule


Management of the solitary pulmonary nodule.

Curr Opin Pulm Med 2019 Apr 9. Epub 2019 Apr 9.

Department of Pulmonary Medicine, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Purpose Of Review: We review the categorization and management of solitary pulmonary nodules.

Recent Findings: The National Comprehensive Cancer Network guidelines were updated in 2018 and the revised Fleischner Society guidelines were published in 2017. The revised Fleischner Society guidelines published in 2017 have less frequent follow-up recommendations for incidentally detected pulmonary nodules with longer intervals between subsequent CT scans. Read More

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http://dx.doi.org/10.1097/MCP.0000000000000586DOI Listing
April 2019
4 Reads

Symptomatic pulmonary sclerosing hemangioma: a rare case of a solitary pulmonary nodule in a woman of advanced age.

J Int Med Res 2019 Apr 10:300060519840898. Epub 2019 Apr 10.

1 Department of Respiratory Medicine, Wuhan Third Hospital (Tongren Hospital of Wuhan University), Hubei, China.

Background: Pulmonary sclerosing hemangioma (PSH) is a rare tumor that usually develops in middle-aged Asian women. PSH has four histological types (hemorrhagic, sclerotic, solid, and papillary) and often grows slowly in a lower lobe of the lung. Preoperative misdiagnosis frequently occurs because of the absence of specific clinical manifestations and imaging findings. Read More

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http://dx.doi.org/10.1177/0300060519840898DOI Listing
April 2019
1 Read
1.095 Impact Factor

Evaluation of the solitary pulmonary nodule.

Intern Med J 2019 Mar;49(3):306-315

Department of Respiratory Medicine, Ipswich General Hospital, Brisbane, Queensland, Australia.

The solitary pulmonary nodule represents a common diagnostic challenge for clinicians. While most are benign, a significant number represent early, potentially curable lung cancers. With the increased utilisation of chest computed tomography, solitary pulmonary nodules are increasingly being identified and with lung cancer screening programmes now on the horizon globally, it is crucial clinicians are familiar with the evaluation and management of solitary pulmonary nodules. Read More

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http://dx.doi.org/10.1111/imj.14219DOI Listing
March 2019
3 Reads

Pulmonary sclerosing pneumocytoma presenting as slow-growing multiple nodules over a long period.

Radiol Case Rep 2019 May 7;14(5):602-607. Epub 2019 Mar 7.

Department of Pathology, The Jikei University School of Medicine, Tokyo, Japan.

Pulmonary sclerosing pneumocytoma is an uncommon slow-growing benign tumor that usually occurs in middle-aged women and generally presents as a solitary well-defined nodule. An 18-year-old woman was incidentally detected to have multiple lung nodules on chest radiography that slowly increased in size over a period of 7 years. Computed tomography images showed multiple well-defined nodules surrounded by numerous smaller nodules with a maximum diameter of 3 cm in the left lung. Read More

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http://dx.doi.org/10.1016/j.radcr.2019.02.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407144PMC
May 2019
1 Read

Arterial Gas Embolism: A Rare Complication of Core Needle Biopsy in the Diagnosis of Solitary Pulmonary Nodule.

Arch Bronconeumol 2019 Mar 16. Epub 2019 Mar 16.

Servicio de Radiología, Hospital General Universitario Gregorio Marañón, Madrid, España.

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http://dx.doi.org/10.1016/j.arbres.2019.02.003DOI Listing
March 2019
1 Read

Correlation study between dual source CT perfusion imaging and the microvascular composition of solitary pulmonary nodules.

Lung Cancer 2019 Apr 16;130:115-120. Epub 2019 Feb 16.

Department of Radiology, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou Province, China. Electronic address:

Objective: To explore the correlation between dual source computed tomography perfusion imaging (CTPI) and microvascular parameters, and evaluate the value of CTPI in the differential diagnosis of solitary pulmonary nodule (SPN).

Methods: 65 consecutive patients with SPN who successfully underwent pre-operative CT perfusion imaging with dual source CT and received a final diagnosis by postoperative pathology. The cases were divided into malignant, benign and inflammatory groups according to the pathological results. Read More

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http://dx.doi.org/10.1016/j.lungcan.2019.02.013DOI Listing
April 2019
1 Read

The value of 18F-FDG PET/CT in the diagnosis of different size of solitary pulmonary nodules.

Medicine (Baltimore) 2019 Mar;98(11):e14813

The First Affiliated Hospital of Soochow University, Suzhou.

This study aimed to evaluate the diagnostic value of F-fluorodeoxyglucose (F-FDG) positron emission tomography/computed tomography (PET/CT) for solitary pulmonary nodules (SPNs) with different diameters.One hundred eighty two consecutive patients with SPN who underwent F-FDG PET/CT examination were retrospectively studied. Patients were categorized into 3 groups according to the diameter of nodules: Group A with the diameter of greater than or equal to 6 mm and less than or equal to 10 mm; Group B with diameter greater than 10 mm and less than or equal to 20 mm; Group C with diameter greater than 20 mm and less than or equal to 30 mm. Read More

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http://dx.doi.org/10.1097/MD.0000000000014813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426628PMC
March 2019
1 Read

Interventional therapy in patients with severe emphysema: evaluation of contraindications and their incidence.

Ther Adv Respir Dis 2019 Jan-Dec;13:1753466619835494

Pneumology and Critical Care Medicine, Thoraxklinik at University of Heidelberg, Heidelberg, Germany, and Translational Lung Research Center Heidelberg (TLRCH, German Center for Lung Research), Heidelberg, Germany.

Background: Endoscopic and surgical interventions may be beneficial for selected patients with emphysema. Rates of treatment failure decrease when the predictors for successful therapy are known. The aim of the study was to evaluate the number of patients with severe emphysema who were not eligible for any intervention, and the reasons for their exclusion. Read More

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http://dx.doi.org/10.1177/1753466619835494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421604PMC
March 2019
2 Reads

Safety and efficacy of computed tomography-guided dye localization using patent blue V for single lung nodule for video-assisted thoracoscopic surgery: a retrospective study.

Ann Transl Med 2019 Jan;7(2):28

Department of Medical Imaging, National Taiwan University Hospital and National Taiwan University College of Medicine, Taichung, Taiwan.

Background: For invisible or impalpable lung nodules, video-assisted thoracoscopic surgery (VATS) has some limitations; some preoperative localization has been developed to overcome this limitation. This study aimed to assess the safety and efficacy of preoperative computed tomography (CT)-guided localization with patent blue V dye.

Methods: In this retrospective study, we examined patients with solitary pulmonary nodule undergoing preoperative CT-guided patent blue V dye localization from 2013 to 2015. Read More

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http://dx.doi.org/10.21037/atm.2019.01.27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381270PMC
January 2019
2 Reads

[Health economics analysis for 18F-fluorodeoxyglucose positron-emission tomography compared with computed tomography in lung cancer].

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2019 Feb;44(2):216-221

PET-CT Center, Second Xiangya Hospital, Central South University, Changsha 410011, China.

Compared with conventional imaging, 18F-fluorodeoxyglucose positron-emission tomography compared with computed tomography (18F-FDG PET/CT) possesses higher sensitivity and specificity in the diagnosis of solitary pulmonary nodule (SPN) and lung cancer. From the perspective of health economics, PET/CT is more suitable strategy for diagnose of SPN with intermediate probability of malignancy, and has good health economics value in preoperative staging diagnosis and follow-up after radiotherapy and chemotherapy of lung cancer. The evaluation method, effect index and comparison method used in the health economics research of PET/CT for lung cancer diagnosis and treatment are cost-effect analysis, life year and incremental cost-effect ratio, respectively. Read More

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http://dx.doi.org/10.11817/j.issn.1672-7347.2019.02.015DOI Listing
February 2019
2 Reads

Lung nodules are reliably detectable on ultra-low-dose CT utilising model-based iterative reconstruction with radiation equivalent to plain radiography.

Clin Radiol 2019 May 1;74(5):409.e17-409.e22. Epub 2019 Mar 1.

General Medicine, Monash Health, Clayton, Victoria, Australia; Monash Imaging, Monash Health, Clayton, Victoria, Australia.

Aim: To determine if ultra-low-dose (ULD) computed tomography (CT) utilising model-based iterative reconstruction (MBIR) with radiation equivalent to plain radiography allows the detection of lung nodules.

Materials And Methods: Ninety-nine individuals undergoing surveillance of solid pulmonary nodules undertook a low-dose (LD) and ULD CT during the same sitting. Image pairs were read blinded, in random order, and independently by two experienced thoracic radiologists. Read More

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http://dx.doi.org/10.1016/j.crad.2019.02.001DOI Listing
May 2019
1 Read

An interesting case of incidental solitary pulmonary nodule.

Breathe (Sheff) 2018 Dec;14(4):e128-e133

Department of pulmonary medicine, ESI PGIMSR, New Delhi, India.


http://ow.ly/N37030mB8Fi. Read More

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http://dx.doi.org/10.1183/20734735.019018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388654PMC
December 2018
1 Read

Solitary Nodular Invasive Mucinous Adenocarcinoma of the Lung: Imaging Diagnosis Using the Morphologic-Metabolic Dissociation Sign.

Korean J Radiol 2019 Mar;20(3):513-521

Department of Radiology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea.

Objective: To evaluate the efficacy of the morphologic-metabolic (M-M) dissociation sign based on computed tomography (CT) and fluorine-18-fluorodeoxyglucose positron emission tomography (PET)/CT in discriminating invasive mucinous adenocarcinoma (IMA) from invasive non-mucinous adenocarcinomas (ADCs) of the lung.

Materials And Methods: The Institutional Review Board approved this retrospective study. Among surgically resected solitary pulmonary nodule (SPN)-type ADCs (< 3 cm in diameter), 35 patients with IMAs and 329 with invasive non-mucinous ADCs were included. Read More

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http://dx.doi.org/10.3348/kjr.2018.0409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389819PMC

Diagnosing a solitary pulmonary nodule using multiple bronchoscopic guided technologies: A prospective randomized study.

Lung Cancer 2019 Mar 16;129:48-54. Epub 2019 Jan 16.

Department of Respiratory and Critical Care Medicine, Tangdu Hospital, Air Force Medical University, Xi'an, PR China. Electronic address:

Background: The rate of detection of pulmonary nodules on computed radiography (CR) is approximately 0.09-0.2%, so rapid identification of the nature of solitary pulmonary nodules (SPNs) with a likelihood of malignancy is a critical challenge in the early diagnosis of lung cancer. Read More

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http://dx.doi.org/10.1016/j.lungcan.2019.01.006DOI Listing
March 2019
1 Read

Prevalence of pulmonary nodules in dogs with malignant neoplasia as determined by CT.

Vet Radiol Ultrasound 2019 Feb 19. Epub 2019 Feb 19.

Department of Clinical Sciences and Services, The Royal Veterinary College, Hertfordshire, United Kingdom.

In order to estimate the prevalence of pulmonary nodules in dogs with nonpulmonary malignant neoplasia, medical record descriptions of CT findings in dogs diagnosed with nonpulmonary malignant neoplasia were reviewed retrospectively. A total of 536 dogs were sampled from a single hospital. For malignant neoplasms with >10 affected individuals, prevalence of multiple pulmonary nodules at first CT was hemangiosarcoma 24 of 58 (41%), osteosarcoma 14 of 55 (26%), carcinoma 20 of 80 (25%), histiocytic sarcoma five of twenty-one (24%), soft tissue sarcoma 13 of 57 (23%), adenocarcinoma 11 of 60 (18%), melanoma five of thirty-seven (14%), lymphoma 10 of 76 (13%), mast cell tumor two of forty-seven (4%), and squamous cell carcinoma zero of seventeen (0%). Read More

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http://dx.doi.org/10.1111/vru.12723DOI Listing
February 2019
1 Read

Pulmonary histoplasmoma: a disguised malady.

Autops Case Rep 2018 Oct-Dec;8(4):e2018065. Epub 2018 Dec 5.

Universidade de São Paulo, School of Medicine, Department of Surgery. São Paulo, SP, Brazil.

Histoplasmosis is a mycosis caused by the dimorphic fungus, , which is transmitted via dust and aerosols. Lung involvement is the most common, with a varied clinical presentation. Although it is not the only source of infection, is frequently found in bat guano, which is the reason why it is highly prevalent among caving practitioners. Read More

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http://dx.doi.org/10.4322/acr.2018.065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360832PMC
December 2018
1 Read

Usefulness of virtual bronchoscopic navigation combined with endobronchial ultrasound guided transbronchial lung biopsy for solitary pulmonary nodules.

Medicine (Baltimore) 2019 Feb;98(7):e14248

Department of Respiratory Medicine, Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.

Background: The aim of this study was to evaluate the diagnostic utility of virtual bronchoscopic navigation (VBN) combined with endobronchial ultrasound (EBUS) guided transbronchial lung biopsy for solitary pulmonary nodules (SPN).

Methods: A total of 115 patients with suspected SPN who underwent transbronchial lung biopsy were evaluated. The patients were randomly divided into an EBUS (EBUS) group and a virtual bronchoscopic navigation combined with endobronchial ultrasound (VBN+EBUS) group. Read More

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http://dx.doi.org/10.1097/MD.0000000000014248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408138PMC
February 2019
1 Read

Recurrent Metastatic Eccrine Porocarcinoma: A Case Report and Review of the Literature.

Am J Case Rep 2019 Feb 11;20:179-183. Epub 2019 Feb 11.

Division of Hematology and Oncology, Bronx Care Health System, Affiliated with Icahn School of Medicine at Mount Sinai, Bronx, NY, USA.

BACKGROUND Eccrine porocarcinoma, or malignant eccrine poroma, is a rare primary skin tumor that develops in the sixth and seventh decades of life, and can present as a painless and solitary nodule. Histopathology is required to confirm the diagnosis. A rare case is presented of metastatic eccrine porocarcinoma, occurring four years after surgical excision of the primary scalp tumor, and includes a review of the literature. Read More

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http://dx.doi.org/10.12659/AJCR.913440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380207PMC
February 2019
3 Reads

Pulmonary adenofibroma in a sika deer.

J Vet Med Sci 2019 Mar 5;81(3):486-490. Epub 2019 Feb 5.

Department of Veterinary Pathology, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido 069-8501, Japan.

A solitary firm nodule was found in the lung of a sika deer (Cervus nippon yesoensis). Histologically, it was a biphasic lesion composed of epithelial and stromal cell elements and exhibited a leaf-like growth pattern. The epithelial cells were immunohistochemically positive for pancytokeratin, cytokeratin 7, napsin A, and thyroid transcription factor-1, and the stromal cells were positive for vimentin and partially positive for desmin and α-smooth muscle actin. Read More

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http://dx.doi.org/10.1292/jvms.18-0691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451917PMC
March 2019
3 Reads

Solitary pulmonary nodule: An interesting clinical mimicry of pulmonary tuberculosis.

Med J Armed Forces India 2019 Jan 15;75(1):115-118. Epub 2018 Oct 15.

Assistant Professor (Lab Sciences & Molecular Med), Army Hospital (R&R), New Delhi 110010, India.

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http://dx.doi.org/10.1016/j.mjafi.2018.07.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349671PMC
January 2019
8 Reads

Changes in quantitative parameters of pulmonary nonsolid nodule induced by lung inflation according to paired inspiratory and expiratory computed tomography imaging.

Eur Radiol 2019 Jan 28. Epub 2019 Jan 28.

Department of Radiology, Changzheng Hospital, Second Military Medical University, No. 415 Fengyang Road, Shanghai, 200003, China.

Objective: To evaluate quantitative parameters of nonsolid nodules on paired inspiratory and expiratory computed tomography (CT) and to examine whether these parameters are sensitive to lung inflation reflected by lung volume.

Methods: Thirty-three patients with 41 nonsolid nodules were included in this prospective study. Paired inspiratory and low-dose respiratory plain chest CT were performed. Read More

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http://link.springer.com/10.1007/s00330-018-5970-5
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http://dx.doi.org/10.1007/s00330-018-5970-5DOI Listing
January 2019
19 Reads

Invasive Pulmonary Adenocarcinoma with Lepidic Growth Pattern in a Pregnant Patient.

Case Rep Oncol 2018 Sep-Dec;11(3):822-834. Epub 2018 Dec 11.

University of Groningen, University Medical Center Groningen, Department of Neurology, Groningen, The Netherlands.

Among the differential diagnoses that should be considered in acute respiratory failure (ARF) are infectious processes, autoimmune diseases, interstitial pulmonary fibrosis, and pulmonary neoplasia. Timely diagnosis of lung neoplasia is complicated in the early stages. An opportune diagnosis, as well as the specific treatment, decrease mortality. Read More

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http://dx.doi.org/10.1159/000495460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341323PMC
December 2018
14 Reads

[Treatment principle and surgical technique of pulmonary ground glass nodules].

Zhonghua Zhong Liu Za Zhi 2019 Jan;41(1):6-9

Department of thoracic surgery, Zhongshan hospital, Fudan university, Shanghai 200032, China.

Pulmonary ground glass nodule (GGN) is a term of radiological manifestation, which may be malignant or benign. GGN's imaging performance is diverse, and the management for pulmonary GGN remains controversial. Numerous clinical studies have clarified the safety of GGN follow-up and longer follow-up intervals, stricter surgical or biopsy indications are recommended. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0253-3766.2019.01.002DOI Listing
January 2019
1 Read

[Combination of CT mulitplane 3D reconstruction, radial endobronchial ultrasound and rapid on-site evaluation for diagnosing peripheral solitary pulmonary nodules].

Zhonghua Yi Xue Za Zhi 2019 Jan;99(2):93-98

Department of Respiratory Medicine, General Hospital of Eastern Theater Command, the Institute of Respiratory Diseases of Nanjing University, Nanjing 210002, China.

To evaluate the diagnostic efficiency of combination of CT multiplane 3D reconstruction (CT-3DR), radial endobronchial ultrasound (R-EBUS), and rapid on-site evaluation (ROSE) for peripheral solitary pulmonary nodules (SPN). A total of 176 patients with peripheral solitary pulmonary nodule were included from the Nanjing Chest Hospital from March 2016 to March 2017. According to different methods, all the patients were divided into four groups: EG (i. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.02.004DOI Listing
January 2019
10 Reads

False positive reduction in pulmonary nodule classification using 3D texture and edge feature in CT images.

Technol Health Care 2019 Jan 9. Epub 2019 Jan 9.

Background: Pulmonary nodule detection can significantly influence the early diagnosis of lung cancer while is confused by false positives.

Objective: In this study, we focus on the false positive reduction and present a method for accurate and rapid detection of pulmonary nodule from suspective regions with 3D texture and edge feature.

Methods: This work mainly consists of four modules. Read More

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http://dx.doi.org/10.3233/THC-181565DOI Listing
January 2019
5 Reads

Is 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography useful to discriminate metachronous lung cancer from metastasis in patients with oncological history?

Q J Nucl Med Mol Imaging 2019 Jan 17. Epub 2019 Jan 17.

Nuclear Medicine Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy -

Background: Solitary pulmonary nodules detected during follow-up in patients with previous cancer history have a high probability of malignancy being either a metachronous lung cancer or a metastasis. This distinction represents a crucial issue in the perspective of "personalized medicine", implying different treatments and prognosis. Aim - to evaluate the role of 18F-Fluorodeoxyglucose (18F-FDG) Positron Emission Tomography/Computed Tomography (PET/CT) in distinguishing whether solitary pulmonary nodules are metachronous cancers or metastases and the relationship between the nodule's characteristics and their nature. Read More

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http://dx.doi.org/10.23736/S1824-4785.19.03140-6DOI Listing
January 2019
2 Reads

PET Counting Response Variability Depending on Tumor Location, Activity, and Patient Obesity: A Feasibility Study of Solitary Pulmonary Nodule Using Monte Carlo.

IEEE Trans Med Imaging 2019 Jan 10. Epub 2019 Jan 10.

We aim to investigate the counting response variations of Positron Emission Tomography (PET) scanners with different detector configurations in the presence of Solitary Pulmonary Nodule (SPN). Using experimentally validated Monte Carlo simulations, the counting performance of four different scanner models with varying tumor activity, location, and patient obesity is represented using NECR (Noise Equivalent Count Rate). NECR is a well-established quantitative metric which has positive correlation with clinically perceived image quality. Read More

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http://dx.doi.org/10.1109/TMI.2019.2891578DOI Listing
January 2019
9 Reads

Visual assessment of calcification in solitary pulmonary nodules on chest radiography: correlation with volumetric quantification of calcification.

Eur Radiol 2019 Jan 7. Epub 2019 Jan 7.

Department of Radiology, Ajou University Medical Center, 164 Worldcup Road, Yeongtong-gu, Suwon, 16499, South Korea.

Purpose: To assess the ability of digital chest radiography (CXR) to reveal calcification in solitary pulmonary nodules (SPNs), and to examine the correlation between a visual assessment and volumetric quantification of the calcification.

Materials And Methods: This study was a retrospective review of 220 SPNs identified by both CXR and chest CT. Eleven observers did blind review of the CXR images and scored nodule calcification on a confidence scale of 1 to 5. Read More

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http://dx.doi.org/10.1007/s00330-018-5883-3DOI Listing
January 2019
3 Reads

Clinical application of planar puncture template-assisted computed tomography-guided percutaneous biopsy for small pulmonary nodules.

J Cancer Res Ther 2018 ;14(7):1632-1637

Department of Radiation Oncology, Peking University Third Hospital, Beijing; China Northern Radioactive Brachytherapy Group, Tangshan People's Hospital, Tangshan, Hebei, China.

Aims: The aims of this study were to evaluate the clinical application of planar puncture template (PPT) in computed tomography (CT)-guided percutaneous needle lung biopsy.

Subjects And Methods: A total of 56 patients with small pulmonary nodules who received CT-guided percutaneous lung biopsy assisted by PPT were included in the study. Five steps were included in the study: fixing position, CT scanning and designing needle pathway, installing navigation system and template, puncturing fixation needle, and performing biopsy needle insertion and biopsy. Read More

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http://dx.doi.org/10.4103/jcrt.JCRT_1017_17DOI Listing
February 2019
3 Reads

Folate-receptor-positive circulating tumor cells as an efficacious biomarker for the diagnosis of small pulmonary nodules.

J Cancer Res Ther 2018 ;14(7):1620-1626

Department of Thoracic Surgery, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, Sichuan, China.

Objective: The objective of this study is to investigate the clinical significance of folate-receptor-positive circulating tumor cells (FR+CTC) for the diagnosis of lung cancer, especially in early-stage patients.

Materials And Methods: A total of 72 lung cancer patients, including 31 with stage I diseases and two with stage 0 diseases, were enrolled in this study. Twenty-four patients with benign lung diseases and two healthy volunteers served as the control group. Read More

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http://dx.doi.org/10.4103/jcrt.JCRT_905_17DOI Listing
February 2019
1 Read

Application value of coaxial biopsy system in needle cutting biopsy for focal ground glass-like density nodule.

J Cancer Res Ther 2018 ;14(7):1509-1514

Department of Radiology, The Affiliated Hospital of Qingdao University, 266101, Shandong, China.

Objective: The objective of the study is to evaluate the clinical efficacy and accuracy of coaxial biopsy puncture applied to make a diagnosis in 76 patients diagnosed with focal ground-glass density nodule (GGN).

Materials And Methods: In total, 76 patients were diagnosed with pure GGN (pGGN), 24 males and 52 females, aged (52 ± 1.2) years on average (range: 47-72 years). Read More

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http://dx.doi.org/10.4103/jcrt.JCRT_382_18DOI Listing
February 2019
2 Reads

Primary Pulmonary Chordoid Meningioma.

Korean J Thorac Cardiovasc Surg 2018 Dec 5;51(6):410-414. Epub 2018 Dec 5.

Department of Pathology, Hanyang University Seoul Hospital, Hanyang University College of Medicine.

Primary pulmonary meningioma is a rare disease, and chordoid meningioma is an uncommon variant of meningioma in the central nervous system (CNS) with a high recurrence rate. We report a case of primary pulmonary chordoid meningioma that presented as a solitary pulmonary nodule (SPN). The SPN was resected by thoracoscopic wedge resection and was revealed to have characteristics of chordoid meningioma. Read More

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http://dx.doi.org/10.5090/kjtcs.2018.51.6.410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301318PMC
December 2018
4 Reads

Can spectral computed tomography imaging improve the differentiation between malignant and benign pulmonary lesions manifesting as solitary pure ground glass, mixed ground glass, and solid nodules?

Thorac Cancer 2019 Feb 23;10(2):234-242. Epub 2018 Dec 23.

Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Radiology, Peking University Cancer Hospital & Institute, Beijing, China.

Background: This study quantitatively assessed the efficacy of spectral computed tomography (CT) imaging parameters for differentiating the malignancy and benignity of solitary pulmonary nodules (SPNs) manifesting as ground glass nodules (GGNs) and solid nodules (SNs).

Methods: The study included 114 patients with SPNs (61 GGNs, and 53 SNs) who underwent CT plain and enhanced scans in the arterial (a) and venous (v) phases using the spectral imaging mode. The spectral CT imaging parameters included: iodine concentrations (IC) of lesions in the arterial (ICLa) and venous (ICLv) phases; normalized IC (NICa/NICv, normalized to the IC in the aorta); the slope of the spectral Hounsfield unit (HU) curve (λHUa/λHUv); and monochromatic CT number (CT40keVa/v, CT70keVa/v) enhancement on 40 and 70 keV images. Read More

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http://dx.doi.org/10.1111/1759-7714.12937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360238PMC
February 2019
2 Reads

Update on radioguided surgery: from international consensus on sentinel node in head and neck cancer to the advances on gynaecological tumors and localization of non-palpable lesions.

Rev Esp Med Nucl Imagen Mol 2018 Dec 19. Epub 2018 Dec 19.

Servicio de Medicina Nuclear, Complejo Hospitalario de Navarra , Pamplona, Navarra, España. Electronic address:

The aim of this review is to provide an updated perspective on different fields of radioguided surgery. With reference to the sentinel lymph node biopsy in oral squamous cell carcinoma, we present the results of the interactive debate held at the recent Congress of our specialty about the more relevant aspects of the London Consensus. Drainage peculiarities and indications according to the current guidelines on gynaecological tumours, endometrial and cervical cancer, are detailed and new scenarios for nuclear medicine physicians are presented; robotic surgery and hybrid tracers, for instance. Read More

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http://dx.doi.org/10.1016/j.remn.2018.10.007DOI Listing
December 2018
2 Reads

Erythroderma and a Pulmonary Nodule.

N Engl J Med 2018 Dec;379(24):e41

University Hospital of Parma, Parma, Italy

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http://dx.doi.org/10.1056/NEJMicm1802572DOI Listing
December 2018
2 Reads

Cyst-related primary lung malignancies: an important and relatively unknown imaging appearance of (early) lung cancer.

Eur Respir Rev 2018 Dec 19;27(150). Epub 2018 Dec 19.

Dept of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.

It is well known that lung cancer can manifest itself in imaging as solid and subsolid nodules or masses. However, in this era of increased computed tomography use another morphological computed tomography appearance of lung cancer is increasingly being recognised, presenting as a malignancy in relation to cystic airspaces. Despite the fact that it seems to be a relatively common finding in daily practice, literature on this entity is scarce and presumably the overall awareness is limited. Read More

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http://dx.doi.org/10.1183/16000617.0079-2018DOI Listing
December 2018
1 Read

Solitary pulmonary metastasis from a gingival cancer of 36 years ago: A case report.

Int J Surg Case Rep 2018 24;53:436-440. Epub 2018 Nov 24.

Departments of General Thoracic Surgery, Seirei Hamamatsu General Hospital, Japan.

Introduction: Unlike a squamous cell carcinoma (SqCC), an adenoid cystic carcinoma (ACC) is an uncommon histology of all head and neck cancers. The clinical significance of a pulmonary metastasectomy differs greatly between these two types of cancers. A solitary pulmonary nodule in a patient with a history of both these different malignancies is a diagnostic and therapeutic challenge. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.11.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262786PMC
November 2018
3 Reads

[Mimics of lung cancer].

Radiologe 2019 Jan;59(1):57-70

Institut für Röntgendiagnostik, Otto-Wagner-Spital, Baumgartner Höhe 1, 1140, Wien, Österreich.

Lung cancer is a histologically, immunologically and therefore morphologically and functionally very heterogeneous group of neoplasms with the highest cancer mortality worldwide. Therefore, the range of diseases mimicking lung cancer is also very broad and includes congenital, infectious and inflammatory changes as well as other benign space-occupying lesions and other primary and secondary pulmonary neoplasms. The difficulty in radiology lies in the ability to diagnose lung cancer with a high degree of certainty. Read More

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http://dx.doi.org/10.1007/s00117-018-0476-3DOI Listing
January 2019
7 Reads

F-FDG PET/CT diagnostic performance in solitary and multiple pulmonary nodules detected in patients with previous cancer history: reports of 182 nodules.

Eur J Nucl Med Mol Imaging 2019 02 8;46(2):429-436. Epub 2018 Dec 8.

Nuclear Medicine Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Francesco Vito, 1, 00168, Roma, Italia.

Purpose: In oncological patients, F-FDG PET/CT performance for pulmonary nodules' characterization is not well-established. Thus, the purpose of this study was to evaluate the F-FDG PET/CT diagnostic performance in pulmonary nodules detected during follow-up in oncological patients and the relationship between malignancy and nodules' characteristics.

Methods: We retrospectively evaluated 182 pulmonary nodules (121 solitary, 61 multiple; mean size = 16. Read More

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http://dx.doi.org/10.1007/s00259-018-4226-6DOI Listing
February 2019
5 Reads

[Comparative analysis of computed tomography texture features between pulmonary inflammatory nodules and lung cancer].

Zhonghua Zhong Liu Za Zhi 2018 Nov;40(11):847-850

Department of Radiology, Shanxi Dayi Hospital, Taiyuan 030032, China.

To investigate the value of computed tomography (CT) texture analysis in differential diagnosis of inflammatory and malignant pulmonary nodules. The image data of 54 patients with lung cancer and 36 patients with pulmonary inflammatory nodules were retrospectively collected in our hospital. All the patients received chest CT scan. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0253-3766.2018.11.010DOI Listing
November 2018
16 Reads

CT-based radiomics signature for differentiating solitary granulomatous nodules from solid lung adenocarcinoma.

Lung Cancer 2018 Nov 17;125:109-114. Epub 2018 Sep 17.

Department of Radiology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China; National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Disease, State Key Laboratory of Respiratory Diseases, Guangzhou, China. Electronic address:

Objectives: Pulmonary granulomatous nodule (GN) with spiculated or lobulated appearance are indistinguishable from solid lung adenocarcinoma (SADC) based on CT morphological features, and partial false-positive findings on PET/CT. The objective of this study was to investigate the ability of quantitative CT radiomics for preoperatively differentiating solitary atypical GN from SADC.

Methods: 302 eligible patients (SADC = 209, GN = 93) were evaluated in this retrospective study and were divided into training (n = 211) and validation cohorts (n = 91). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01695002183057
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http://dx.doi.org/10.1016/j.lungcan.2018.09.013DOI Listing
November 2018
14 Reads

Incidental Pulmonary Nodules Detected on CT Images.

JAMA 2018 Dec;320(21):2260-2261

University of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1001/jama.2018.16336DOI Listing
December 2018
2 Reads

Comparative Clinical Analysis of Gastroenteropancreatic Neuroendocrine Carcinomas with Liver Metastasis and Primary Hepatic Neuroendocrine Carcinomas.

Dis Markers 2018 17;2018:9191639. Epub 2018 Oct 17.

Division of Gastroenterology, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430077, China.

Purpose: The objective of this study was to analyze the clinical features and prognosis of gastroenteropancreatic (GEP) neuroendocrine carcinomas (NECs) with liver metastasis and primary hepatic neuroendocrine carcinomas (PHNECs), as these rare hepatic neuroendocrine carcinomas have not been exhaustively studied.

Methods: The clinical data of 47 patients with hepatic NECs were retrospectively reviewed and categorized to analyze features and prognosis.

Results: The 47 studied cases comprised 13 cases of primary hepatic NECs (primary group) and 34 cases of metastatic hepatic NECs (metastatic group). Read More

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http://dx.doi.org/10.1155/2018/9191639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207894PMC
March 2019
2 Reads

Cascaded classifiers and stacking methods for classification of pulmonary nodule characteristics.

Authors:
Aydin Kaya

Comput Methods Programs Biomed 2018 Nov 3;166:77-89. Epub 2018 Oct 3.

Hacettepe University, Computer Engineering Department, 06800 Ankara, Turkey. Electronic address:

Background And Objectives: Detection and classification of pulmonary nodules are critical tasks in medical image analysis. The Lung Image Database Consortium (LIDC) database is a widely used resource for small pulmonary nodule classification research. This dataset is comprised of nodule characteristic evaluations and CT scans of patients. Read More

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http://dx.doi.org/10.1016/j.cmpb.2018.10.009DOI Listing
November 2018
2 Reads

A dynamic model of CT scans for quantifying doubling time of ground glass opacities using histogram analysis.

Math Biosci Eng 2018 10;15(5):1203-1224

Division of Computing Science and Mathematics, University of Stirling, Stirling, FK9 4LA, UK.

We quantify a recent five-category CT histogram based classification of ground glass opacities using a dynamic mathematical model for the spatial-temporal evolution of malignant nodules. Our mathematical model takes the form of a spatially structured partial differential equation with a logistic crowding term. We present the results of extensive simulations and validate our model using patient data obtained from clinical CT images from patients with benign and malignant lesions. Read More

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http://dx.doi.org/10.3934/mbe.2018055DOI Listing
October 2018

Incidental thoracic findings in computed tomography scans before transcatheter aortic valve implantation.

Interact Cardiovasc Thorac Surg 2019 Apr;28(4):559-565

Department of Thoracic Surgery, University Medical Center Regensburg, Regensburg, Germany.

Objectives: Preoperative computed tomography (CT) scans for transcatheter aortic valve implantation (TAVI) are used routinely. In elderly high-risk patients, incidental radiographic findings are frequently reported. The aim of this study was to investigate the impact of auxiliary findings on the patients' mid-term survival, which might affect the treatment strategy. Read More

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http://dx.doi.org/10.1093/icvts/ivy299DOI Listing
April 2019
4 Reads

Outcome of untreated lung nodules with histological but no microbiological evidence of tuberculosis.

BMC Infect Dis 2018 Oct 23;18(1):530. Epub 2018 Oct 23.

Division of Thoracic Surgery, Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.

Background: The outcome of lung nodule(s) with histopathological findings suggestive of tuberculosis (TB) but lack of microbiologic confirmation remains unclear. Whether these patients require anti-TB treatment remains unknown. The aim of the study was to compare the risk of active TB within 4 years in untreated patients with histological findings but no microbiological evidences suggestive of TB. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-018-3442-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199800PMC
October 2018
8 Reads

Comparison of Various Parameters of DWI in Distinguishing Solitary Pulmonary Nodules.

Curr Med Sci 2018 Oct 20;38(5):920-924. Epub 2018 Oct 20.

Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

In order to prospectively assess various parameters of diffusion weighted imaging (DWI) in differential diagnosis of benign and malignant solitary pulmonary nodules (SPNs), 58 patients (40 men and 18 women, and mean age of 48.1±10.4 years old) with SPNs undergoing conventional MR, DWI using b=500 s/mm on a 1. Read More

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http://link.springer.com/10.1007/s11596-018-1963-5
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http://dx.doi.org/10.1007/s11596-018-1963-5DOI Listing
October 2018
28 Reads

Single-view 2D CNNs with fully automatic non-nodule categorization for false positive reduction in pulmonary nodule detection.

Comput Methods Programs Biomed 2018 Oct 31;165:215-224. Epub 2018 Aug 31.

School of Electrical Engineering, Korea Advanced Institute of Science and Technology, Republic of Korea. Electronic address:

Background And Objective: In pulmonary nodule detection, the first stage, candidate detection, aims to detect suspicious pulmonary nodules. However, detected candidates include many false positives and thus in the following stage, false positive reduction, such false positives are reliably reduced. Note that this task is challenging due to 1) the imbalance between the numbers of nodules and non-nodules and 2) the intra-class diversity of non-nodules. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01692607183074
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http://dx.doi.org/10.1016/j.cmpb.2018.08.012DOI Listing
October 2018
10 Reads