4,854 results match your criteria Solitary Pulmonary Nodule


Discriminating between bronchiolar adenoma, adenocarcinoma in situ and minimally invasive adenocarcinoma of the lung with CT.

Diagn Interv Imaging 2020 May 29. Epub 2020 May 29.

Department of Radiology, The Second Hospital of Jilin University, Changchun 130041, Jilin, China.

Purpose: To identify computed tomography (CT) features that may help distinguish bronchiolar adenoma (BA) from lung adenocarcinomas in situ (AIS) and minimally invasive adenocarcinomas (MIA) among lung lesions presenting as ground-glass nodules (GGNs).

Materials And Methods: A total of 140 patients with GGNs confirmed by surgery and pathology, were reviewed retrospectively. There were 68 men and 72 women with a mean age of 64. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.diii.2020.05.005DOI Listing

[Multiple insufficiency fractures (metatarsial, calcaneal and sacral) as the first manifestation of lung adenocarcinoma. A case report and literature review].

Rehabilitacion (Madr) 2020 Jan 6. Epub 2020 Jan 6.

Servicio de Rehabilitación y Medicina Física, Hospital Universitario Santa Cristina, Madrid, España.

Insufficiency fractures, or pathological fractures, are produced after minimal trauma or no prior trauma and normally affect weakened bone. Their presence should be suspected in fractures showing abnormal patterns, when several fractures occur in a short period of time and in those with no apparent or only minimal trauma. On confirmation of an insufficiency fracture, a differential diagnosis should be made between tumoral and metastatic fractures if there is a history of underlying primary malignancy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.rh.2019.11.002DOI Listing
January 2020

Pulmonary nodules precision localization techniques.

Future Oncol 2020 Jun 21;16(16s):15-19. Epub 2020 May 21.

Department of Cardiothoracic Surgery, James Cook University Hospital, Middlesbrough, United Kingdom.

The advent of helical high-resolution CT scanners, the application of screening programs and the follow-up of patient with oncological history, led to an increasing number of diagnosis of small pulmonary nodule (less than 10 mm in maximum diameter), partially solid nodule or completely ground glass ones. Their management is controversial. Excisional biopsy by mean of video-assisted thoracic surgery is often a viable choice but to locate these lesions intraoperatively can be impossible without the aid of preoperative or intraoperative localization techniques. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/fon-2019-0069DOI Listing

Adenocarcinoma of the lung: from BAC to the future.

Insights Imaging 2020 May 19;11(1):69. Epub 2020 May 19.

St James's Hospital, Dublin, 8, Ireland.

Adenocarcinoma in situ, minimally invasive adenocarcinoma, lepidic predominant adenocarcinoma and invasive mucinous adenocarcinoma are relatively new classification entities which replace the now retired term, bronchoalveolar carcinoma (BAC). The radiographic appearance of these lesions ranges from pure, ground glass nodules to large, solid masses. A thorough understanding of the new classification is essential to radiologists who work with MDT colleagues to provide accurate staging and treatment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13244-020-00875-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237554PMC

Solitary pleural nodule: a late paradoxical reaction to antituberculosis treatment.

Radiologia 2020 May 4. Epub 2020 May 4.

Servicio de Radiodiagnóstico, Hospital Vall d'Hebron, Barcelona, España.

We present the case of a young woman with a history of previously treated pleural and pulmonary tuberculosis referred to our hospital for chest pain and a single pleural nodule seen on plain chest films and chest CT. Cultures of inflammatory-type material obtained by US-guided fine-needle biopsy of the pleural lesion were positive for Mycobacterium tuberculosis complex. The diagnosis was a paradoxical reaction to antituberculosis treatment; after 6 more months of treatment, the pleural lesion and chest pain disappeared. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.rx.2020.01.009DOI Listing

Progressively increasing density of the solid center of a ground-glass nodule in a solitary pulmonary capillary hemangioma: A case report.

Pathol Int 2020 May 5. Epub 2020 May 5.

Department of Diagnostic Pathology, NTT Medical Center Tokyo, Tokyo, Japan.

Solitary pulmonary capillary hemangiomas (SPCHs) are recently recognized, rare benign lesions that form solitary nodules owing to capillary proliferation. These lesions are usually detected incidentally as small ground-glass nodules (GGNs) on computed tomography (CT), and progressively enlarge over time. The radiological distinction from peripheral lung cancers is particularly challenging. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pin.12945DOI Listing

Radiomics nomogram for preoperative differentiation of lung tuberculoma from adenocarcinoma in solitary pulmonary solid nodule.

Eur J Radiol 2020 Apr 20;128:109022. Epub 2020 Apr 20.

The Department of Radiology, The Affiliated Jiangmen Hospital of Sun Yat-sen University, Jiangmen, Guangdong Province, China. Electronic address:

Purpose: To investigate the preoperative differential diagnostic performance of a radiomics nomogram in tuberculous granuloma (TBG) and lung adenocarcinoma (LAC) appearing as solitary pulmonary solid nodules (SPSNs).

Method: We retrospectively recruited 426 patients with SPSNs from two centers and assigned them to training (n = 123), internal validation (n = 121), and external validation cohorts (n = 182). A model of deep learning (DL) was built for tumor segmentation from routine computed tomography (CT) images and extraction of 3D radiomics features. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejrad.2020.109022DOI Listing

Optimization of CT windowing for diagnosing invasiveness of adenocarcinoma presenting as sub-solid nodules.

Eur J Radiol 2020 Apr 25;128:108981. Epub 2020 Apr 25.

Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Centre of Cancer, Key Laboratory of Cancer Prevention and Therapy, Department of Radiology, Tianjin, People's Republic of China. Electronic address:

Purpose: To evaluate the optimal window setting to diagnose the invasiveness of lung adenocarcinoma in sub-solid nodules (SSNs).

Methods: We retrospectively included 437 SSNs and randomly divided them 3:1 into a training group (327) and a testing group (110). The presence of a solid component was regarded as indicator of invasiveness. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejrad.2020.108981DOI Listing

Two nomograms based on CT features to predict tumor invasiveness of pulmonary adenocarcinoma and growth in pure GGN: a retrospective analysis.

Jpn J Radiol 2020 Apr 30. Epub 2020 Apr 30.

Radiology Department, The Affiliated ZhongShan Hospital of Dalian University, Dalian University, No. 6, Jiefang Rd, Zhongshan District, Dalian, 116001, China.

Purpose: The aim of the study is to construct two nomograms for predicting the invasive extent of pulmonary adenocarcinoma and nodule growth in patients with pulmonary pure ground-glass nodules (pGGN).

Method: Consecutive patients with pGGNs (n = 172) were retrospectively studied at one institution, formed the development cohort in predicting IPAs' nomogram. A separate cohort of patients with pGGNs (n = 116) from another institution was used for validation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11604-020-00957-xDOI Listing
April 2020
0.742 Impact Factor

PET/CT and the solitary pulmonary nodule.

Radiol Bras 2020 Mar-Apr;53(2):VII-VIII

Honorary Professor of Thoracic Imaging, The University of Manchester, Co-lead for Thoracic Imaging, Department of Radiology, Manchester University NHS Foundation Trust.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1590/0100-3984.2020.53.2e2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170579PMC

Small Solitary Ground-Glass Nodule on CT as an Initial Manifestation of Coronavirus Disease 2019 (COVID-19) Pneumonia.

Korean J Radiol 2020 05;21(5):545-549

Department of Radiology, China Resources & WISCO General Hospital, Wuhan, China.

The 2019 novel coronavirus (2019-nCoV) outbreak in Wuhan, Hubei Province, China in 2019 led to large numbers of people being infected and developing atypical pneumonia (coronavirus disease 2019, COVID-19). Typical imaging manifestations of patients infected with 2019-nCoV has been reported, but we encountered an atypical radiological manifestation on baseline computed tomography (CT) images in three patients from Wuhan, China infected with the 2019-nCoV. Surprisingly, the only similar CT finding was a solitary sub-centimeter ground-glass nodule adjacent to bronchovascular bundles, which could be easily overlooked. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3348/kjr.2020.0240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183840PMC

Use of PET/CT to aid clinical decision-making in cases of solitary pulmonary nodule: a probabilistic approach.

Radiol Bras 2020 Jan-Feb;53(1):1-6

Real Hospital Português de Beneficência em Pernambuco, Recife, PE, Brazil.

Objective: To determine the frequency with which F-FDG-PET/CT findings change the probability of malignancy classification of solitary pulmonary nodules.

Materials And Methods: This was a retrospective analysis of all F-FDG-PET/CT examinations performed for the investigation of a solitary pulmonary nodule between May 2016 and May 2017. We reviewed medical records and PET/CT images to collect the data necessary to calculate the pre-test probability of malignancy using the Swensen model and the Herder model. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1590/0100-3984.2019.0034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159041PMC

[Radiation dose and image quality of noncontrast chest CT in domestic and imported main stream manufacturers].

Zhonghua Yi Xue Za Zhi 2020 Apr;100(15):1148-1153

Department of Radiology, Tianjin Union Medical Center, Tianjin 300121, China.

To compare the radiation dose and image quality of noncontrast chest CT and detection of ground-glass opacity pulmonary nodules (GGN) in domestic 128-slice spiral CT with the other CT scanners from three main stream manufacturers. From May 8, 2018 to October 31, 2018, noncontrast chest CT images from Neusoft 128-slice CT (75 males, 25 females, (42±16) years), dual-source 64-slice CT (53 males, 47 females, (50±16) years) and dual-source 128-slice CT scanners(69 males, 31 females, (62±17) years), Toshiba 128-slice CT (51 males, 49 females, (58±13) years) and GE 128-slice CT scanner (55 males, 45 females, (60±10) years) were collected in Eastern Theater Command and Tianjin People's Hospital. Radiation dose and image quality were evaluated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3760/cma.j.cn112137-20190903-01957DOI Listing

Outcome of PET-Negative Solid Pulmonary Nodules: A Retrospective Study.

Acad Radiol 2020 Apr 14. Epub 2020 Apr 14.

Staten Island University Hospital, Department of Radiology, Staten Island, NY.

Objective: It was observed that malignancy had been found on follow-up in patients with PET-negative solid solitary pulmonary nodules (SPN). A retrospective analysis was performed to observe the natural history and malignant potential of these lesions, which, in routine practice, are presumed to be inactive.

Materials And Methods: Patients with an incidentally-discovered solid solitary pulmonary nodule who then had a negative follow-up PET/CT from 2005 to 2015 were identified using a text-based search methodology. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.acra.2020.03.016DOI Listing

Predictive model for the diagnosis of benign/malignant small pulmonary nodules.

Medicine (Baltimore) 2020 Apr;99(15):e19452

Taizhou First People's Hospital, Taizhou, Zhejiang, China.

There is some doubt that all nodules <8 mm are really mainly benign and that simple follow-up is adequate in all cases. The purpose of this study is to create a predictive model for the diagnosis of benign and malignant small pulmonary nodules.This was a retrospective case-control study of patients who had undergone pulmonary nodule resection at the Zhejiang University Jinhua Hospital. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000019452DOI Listing

[Lung cancer diagnosed by transesophageal ecoendoscopy and fine needle aspiration biopsy].

Medicina (B Aires) 2020 ;80(2):173-176

Servicio de Gastroenterología y Endoscopia, Hospital Alemán, Buenos Aires, Argentina.

Lung cancer is one of the leading causes of death worldwide. Pulmonary nodules located in the vicinity of the mediastinum, retrocardiac, near the aorta or pulmonary vessels, and in front of the spine, may be difficult to access through a percutaneous or bronchoscopic approach. Fine needle aspiration/biopsy guided by transesophageal echoendoscopy (EUS-FNA/FNB) is a minimally invasive method with low morbidity that could allow access to lesions in these places. Read More

View Article

Download full-text PDF

Source
January 2020

Radioguided Surgery, a Cost-Effective Strategy for Treating Solitary Pulmonary Nodules: 20-Year Experience of a Single Center.

Clin Lung Cancer 2020 Mar 7. Epub 2020 Mar 7.

Minimally Invasive and Robotic Thoracic Surgery, Robotic Multispecialty Center for Surgery, University Hospital of Pisa, Pisa, Italy.

Introduction: Surgical resection with minimally invasive approach is the gold standard for both definitive diagnosis and treatment of solitary pulmonary nodules (SPNs); however, it can be difficult to pinpoint small, deep, or subsolid nodes without palpating lung parenchyma. The primary endpoint of this study is showing that radioguided surgery is a cost-effective strategy to improve the effectiveness of video-thoracoscopic localization/resection of SPNs/ground-glass opacities (GGOs). Secondary endpoints are analyzing the morbidity of this technique and tips and tricks to better manage this method. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cllc.2020.02.026DOI Listing

A Subsolid Nodules Imaging Reporting System (SSN-IRS) for Classifying 3 Subtypes of Pulmonary Adenocarcinoma.

Clin Lung Cancer 2020 Feb 6. Epub 2020 Feb 6.

Department of Radiology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Centre of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, The People's Republic of China. Electronic address:

Objectives: To develop an imaging reporting system for the classification of 3 adenocarcinoma subtypes of computed tomography (CT)-detected subsolid pulmonary nodules (SSNs) in clinical patients.

Methods: Between November 2011 and October 2017, 437 pathologically confirmed SSNs were retrospectively identified. SSNs were randomly divided 2:1 into a training group (291 cases) and a testing group (146 cases). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cllc.2020.01.014DOI Listing
February 2020

Diagnosis and management of glandular papilloma of lung: A case report.

World J Clin Cases 2020 Mar;8(6):1104-1107

Division of Thoracic Surgery, Department of Surgery, Tri-Service General Hospital, Taipei 114, Taiwan.

Background: Solitary respiratory papilloma is a rare epithelial tumor that can be categorized into multiple subtypes depending on tumor location, histological presentation and number. The glandular type is the rarest, with only 30 cases available within the field. Hence, information on its identification and treatment is limited. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12998/wjcc.v8.i6.1104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103975PMC

Pulmonary adenocarcinoma appearing as ground-glass opacity nodules identified using non-enhanced and contrast-enhanced CT texture analysis: A retrospective analysis.

Exp Ther Med 2020 Apr 10;19(4):2483-2490. Epub 2020 Feb 10.

Department of Medical Imaging, Yangzhou University Clinical College Subei People's Hospital, Yangzhou, Jiangsu 225002, P.R. China.

The present study aimed to investigate the ability of CT-based texture analysis to differentiate invasive adenocarcinoma (IA) from pre-invasive lesions (PIL) or minimally IA (MIA) appearing as ground-glass opacity (GGO) nodules, and to further compare the performance of non-enhanced CT (NECT) images with that of contrast-enhanced CT (CECT) images. A total of 77 patients with GGO nodules and surgically confirmed pulmonary adenocarcinoma were included in the present retrospective study. Each GGO nodule was manually segmented and its texture features were extracted from NECT and CECT images using in-house developed software coded in MATLAB (MathWorks). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3892/etm.2020.8511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086215PMC

A case of a primary pulmonary meningioma mimicking a metastasis from a papillary thyroid carcinoma due to a size reduction after radioactive iodine therapy.

Surg Case Rep 2020 Mar 27;6(1):57. Epub 2020 Mar 27.

Department of General Thoracic Surgery, Seirei Hamamatsu General Hospital, 2-12-12, Sumiyoshi, Naka-ku, Hamamatsu, Shizuoka, 430-8558, Japan.

Background: Primary pulmonary meningiomas (PPMs) are a rare mostly benign disease presenting as a solitary pulmonary nodule and are hardly distinguishable from a metastatic tumor because of a lack of specific radiological features. We described a case of a PPM initially diagnosed as a metastatic lung tumor from thyroid cancer with a size reduction after radioactive iodine therapy.

Case Presentation: A 62-year-old woman who had undergone a total thyroidectomy for a papillary thyroid carcinoma 6 years prior presented with an enlarging pulmonary nodule. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40792-020-00823-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101463PMC

Differences in the clinical management of women and men after detection of a solitary pulmonary nodule in clinical practice.

Eur Radiol 2020 Mar 19. Epub 2020 Mar 19.

Public Health, History of Science and Gynaecology Department, Miguel Hernández University, Nacional Road N-332, s/n, 03550, San Juan de Alicante, Alicante, Spain.

Objectives: To explore differences in the clinical management of men and women in the 5 years after detecting a solitary pulmonary nodule (SPN) by chest radiograph or CT in routine clinical practice.

Methods: We followed up 545 men and 347 women with an SPN detected by chest radiograph or CT in a retrospective cohort of 25,422 individuals undergoing routine thoracic imaging in 2010-2011. We compared the frequency of each management strategy (no further test, immediate intervention or follow up) according to sex by means of chi-squared. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00330-020-06791-zDOI Listing

The multicenter ITALIAN trial assess the performance of FDG-PET/CT related to pre-test cancer risk in patients with solitary pulmonary nodules and introduces a segmental thoracic diagnostic strategy.

Curr Radiopharm 2020 Mar 18. Epub 2020 Mar 18.

Section Health and Development, Interuniversity Research Center for Sustainability (CIRPS) , Italy.

Purpose: The Italian Tailored Assessment of Lung Indeterminate Accidental Nodule (ITALIAN) trial is a trial drawn to determine the performance of 18F-FDG-PET/CT in patients with solitary pulmonary nodules (SPN) , stratified for different kind of risk. An additional end-point was to compare the diagnostic information and estimated dosimetry, provided by a segmental PET/CT (s-PET/CT) acquisition instead of a whole body PET/CT (wb-PET/CT), in order to evaluate if segmental thoracic PET/CT can be used in patients with SPN.

Methods: 18F-FDG PET/CT of 502 patients, stratified for pre-test cancer risk, were retrospectively analyzed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1874471013666200318142210DOI Listing

Cost-Effectiveness of Follow-Up for Subsolid Pulmonary Nodules in High-Risk Patients.

J Thorac Oncol 2020 Apr 6. Epub 2020 Apr 6.

Institute for Technology Assessment, Massachusetts General Hospital, Boston, Massachusetts. Electronic address:

Objective: To evaluate the cost-effectiveness of a number of follow-up guidelines and variants for subsolid pulmonary nodules.

Methods: We used a simulation model informed by data from the literature and the National Lung Screening Trial to simulate patients with ground-glass nodules (GGNs) detected at baseline computed tomography undergoing follow-up. The nodules were allowed to grow and develop solid components over time. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtho.2020.03.001DOI Listing

[Effectiveness and safety of CT-guided percutaneous intrapulmonary injection of indocyanine green for localization of pulmonary nodules and ground glass opacity].

Zhonghua Yi Xue Za Zhi 2020 Feb;100(7):538-540

Minimally Invasive Treatment Center, Beijing Chest Hospital, Beijing 101149, China.

To investigate the effectiveness and safety of CT-guided intrapulmonary injection of indocyanine green (ICG) for preoperative localization of small pulmonary nodules and ground glass opacities. From October 2018 to July 2019, a total of 34 consecutive patients (39 nodules) who were suspected to be lung cancer and underwent thoracoscopic surgery were enrolled. The size of the nodules was 0. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2020.07.012DOI Listing
February 2020

A model of malignant risk prediction for solitary pulmonary nodules on F-FDG PET/CT: Building and estimating.

Thorac Cancer 2020 May 12;11(5):1211-1215. Epub 2020 Mar 12.

PET/CT Center, the Affiliated Hospital of Qingdao University, Qingdao, China.

Background: To develop a model of malignant risk prediction of solitary pulmonary nodules (SPNs) using metabolic characteristics of lesions.

Methods: A total of 362 patients who underwent PET/CT imaging from January 2013 to July 2017 were analyzed. Differences in the clinical and imaging characteristics were analyzed between patients with benign SPNs and those with malignant SPNs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/1759-7714.13375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180535PMC

Radiomics for lung adenocarcinoma manifesting as pure ground-glass nodules: invasive prediction.

Eur Radiol 2020 Mar 11. Epub 2020 Mar 11.

Department of Radiology, Huadong Hospital Affiliated to Fudan University, Shanghai, 200040, China.

Objectives: To investigate the value of radiomics based on CT imaging in predicting invasive adenocarcinoma manifesting as pure ground-glass nodules (pGGNs).

Methods: This study enrolled 395 pGGNs with histopathology-confirmed benign nodules or adenocarcinoma. A total of 396 radiomic features were extracted from each labeled nodule. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00330-020-06776-yDOI Listing

[Surgical Resection of a Solitary Pulmonary Nodule in a Patient with Breast Cancer-A Case Report].

Gan To Kagaku Ryoho 2019 Dec;46(13):2084-2086

Dept. of Surgery, Chiba Rosai Hospital.

Solitary lung tumors after radical surgery for breast cancer often present difficulty in diagnosis and treatment. This report describes the case of a patient with a previous history of radicalsurgery for breast cancer who underwent lung surgery. Solitary pulmonary nodules should be diagnosed in patients with breast cancer, because treatments and prognoses differ between metastatic and primary tumors. Read More

View Article

Download full-text PDF

Source
December 2019

68Ga-FAPI PET/CT Improves Therapeutic Strategy by Detecting a Second Primary Malignancy in a Patient With Rectal Cancer.

Clin Nucl Med 2020 Jun;45(6):468-470

Department of Radiation Oncology, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, Teaching Hospital of Fujian Medical University, Xiamen, China.

A 71-year-old man with pathologically confirmed rectal cancer underwent F-FDG PET/CT before radical operation, which showed multiple nodules with low uptake in bilateral pleura and 1 solitary pulmonary nodule with slight uptake in left lung. The subpleural nodule was diagnosed as benign lesion through the biopsy. Ga-labeled fibroblast-activation-protein inhibitor PET/CT was performed for further evaluation, which showed low uptake in bilateral subpleural nodules but focally increased uptake in the nodule of left lung. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/RLU.0000000000003000DOI Listing
June 2020
3.931 Impact Factor

An 80-Year-Old Woman With a Solitary Pulmonary Nodule.

Chest 2020 Mar;157(3):e85-e89

Pathology Department, Centre de Biologie Pathologie, University of Lille, CHU Lille, Lille, France.

Case Presentation: An 80-year-old-woman was referred for evaluation of chest pain that appeared after providing care at home for her sick husband, which included helping him to get up and move about. The pain was initially triggered by lifting heavy objects but then became constant, without exacerbating or relieving factors. The pain was located in the left hemithorax and was not associated with shortness of breath or cough. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chest.2019.10.056DOI Listing

[Clinical analysis of 30 cases of Castleman disease with different types of thoracic involvement].

Zhonghua Xue Ye Xue Za Zhi 2020 Feb;41(2):149-156

National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, Guangzhou 510120, China.

To improve the clinical understanding of Castleman disease (CD) with different types of thoracic involvement, including their clinical features, radiological and pathological findings, diagnosis and current treatment strategies. Retrospective analysis of 30 patients diagnosed with CD with thoracic involvement and hospitalized between June 2009 and May 2019 in The First Affiliated Hospital of Guangzhou Medical University was performed. Patients were divided into three groups for subsequent analysis based on the clinical data: CD with bronchiolitis obliterans (BO) , unicentric Castleman disease (UCD) without BO, and multicentric Castleman disease (MCD) without BO. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2020.02.012DOI Listing
February 2020

Towards more accurate F-fluorodeoxyglucose positron emission tomography (F-FDG PET) imaging in active and latent tuberculosis.

Int J Infect Dis 2020 Mar 27;92S:S85-S90. Epub 2020 Feb 27.

Institute of Nuclear Medicine, UCLH NHS Foundation Trust, 235 Euston Road, London NW1 2BU, United Kingdom. Electronic address:

Tuberculosis (TB) is one of the leading causes of death worldwide. Although the disease is curable and preventable, it is underdiagnosed in many parts of the world. Positron emission tomography (PET) imaging using F-FDG in TB can localise disease sites and the extent of disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijid.2020.02.017DOI Listing

Technologies for targeting the peripheral pulmonary nodule including robotics.

Respirology 2020 Feb 26. Epub 2020 Feb 26.

Department of Respiratory Medicine, National Hospital Organization Nagoya Medical Center, Nagoya, Japan.

Bronchoscopic sampling of PPL was significantly advanced by the development of the endobronchial ultrasound guide sheath method in the 1990s. Since then, a range of technical and procedural techniques have further advanced diagnostic yields. These include the use of thinner bronchoscopes with better working channel diameters, understanding the importance of peripheral transbronchial needle aspiration, and virtual bronchoscopic assistance. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/resp.13791DOI Listing
February 2020

An ectopic Cushing's syndrome as a cause of severe refractory hypokalemia in the ICU.

Acta Clin Belg 2020 Feb 23:1-6. Epub 2020 Feb 23.

Department of Intensive Care, Brugmann University Hospital, Brussels, Belgium.

: Ectopic Cushing's syndrome is a very rare condition caused by an ACTH-secreting tumor outside the pituitary or adrenal glands, and the majority of these cases are encountered in the context of paraneoplastic syndromes. The ectopic source of ACTH secretion is not always obvious to detection and can be challenging. We report a rare case, in which a hidden ACTH-secreting carcinoid tumor of the lung caused a severe refractory hypokalemia, leading us to a race against time to locate the tumor. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/17843286.2020.1734162DOI Listing
February 2020

Quantitative volumetric metabolic measurement of solitary pulmonary nodules by F-18 fluorodeoxyglucose positron emission tomography-computed tomography.

Turk Gogus Kalp Damar Cerrahisi Derg 2019 Oct 23;27(4):557-564. Epub 2019 Oct 23.

Department of Pathologhy, Pamukkale University Medical Faculty, Denizli, Turkey.

Background: This study aims to evaluate the effect of quantitative volumetric metabolic measurements in F-18 fluorodeoxyglucose positron emission tomographycomputed tomography to distinguish benign and malignant solitary pulmonary nodules.

Methods: We retrospectively reviewed 78 patients (56 males; 22 females; mean age 61±11.9 years; range, 32 to 82 years) with solitary pulmonary nodules who underwent F-18 fluorodeoxyglucose positron emission tomography-computed tomography. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5606/tgkdc.dergisi.2019.17582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018152PMC
October 2019

Pulmonary Hyalinizing Granuloma Mimicking Primary Lung Cancer: An Unusual Case Involving a Pulmonary Tumor.

Case Rep Pulmonol 2020 21;2020:3268608. Epub 2020 Jan 21.

Department of Chest Surgery, St. Marianna University School of Medicine, Kawasaki 216-8511, Japan.

Pulmonary hyalinizing granuloma is a very rare benign condition. This study describes a case involving pulmonary hyalinizing granuloma in a 76-year-old man who presented with a solitary pulmonary nodule, determined through chest radiography and computed tomography, that mimicked primary lung cancer. To establish a definitive diagnosis, tumor resection was performed with histopathological analysis indicating pulmonary hyalinizing granuloma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2020/3268608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995493PMC
January 2020

Comparison of the diagnostic accuracy of diffusion-weighted magnetic resonance imaging and positron emission tomography/computed tomography in pulmonary nodules: a prospective study.

Pol J Radiol 2019 27;84:e498-e503. Epub 2019 Nov 27.

Department of Chest Diseases, University of Health Sciences, Haseki Training and Research Hospital, Istanbul, Turkey.

Purpose: Computed tomography (CT) and positron emission tomography (PET) are the mainstay imaging methods in the evaluation and follow-up of pulmonary nodules. But they both have high radiation risk for patients. Diffusion- weighted magnetic resonance imaging (DW-MRI), on the other hand, is a radiation free imaging method that gives information about the biological structure of tissues at the molecular level by measuring random movement of water in biological tissues. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/pjr.2019.91200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016491PMC
November 2019

[Prognosis factors analysis of patients with malignant solitary pulmonary nodules].

Beijing Da Xue Xue Bao Yi Xue Ban 2020 Feb;52(1):158-162

Department of Geriatrics, Peking University First Hospital, Beijing 100034, China.

Objective: To explore the prognosis factors that influence the postoperative survival rate in patients with malignant solitary pulmonary nodules and to provide a reference for the prognosis risk stratification of early lung cancer patients.

Methods: In this study, we retrospectively reviewed 172 patients who were admitted to Peking University First Hospital from April 2006 to December 2013. All cases were radiologically defined as solitary pulmonary nodule and were pathologically confirmed to be stage Ia non-small cell lung cancer after surgical procedure. Read More

View Article

Download full-text PDF

Source
February 2020

Multiple sclerosing hemangioma of the right lung in a 23-year-old female patient: A case report and review of the literature.

Mol Clin Oncol 2020 Mar 22;12(3):263-267. Epub 2020 Jan 22.

Department of Pulmonary and Critical Care Medicine, General Hospital of Western Theater Command, Chengdu, Sichuan 610083, P.R. China.

Pulmonary sclerosing hemangioma (PSH) is a relatively uncommon benign tumor of the lung, predominantly affecting young and middle-aged women. In the majority of the patients, PSH is incidentally found on physical examination and typically presents as a solitary nodule with smooth borders, as it is generally asymptomatic or lacks typical symptoms. In the present case, a 23-year-old woman was incidentally diagnosed with pulmonary nodules during routine physical examination and reported suffering from intermittent fevers for >2 months. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3892/mco.2020.1986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016522PMC

Dynamic contrast-enhanced computed tomography for the diagnosis of solitary pulmonary nodules: a systematic review and meta-analysis.

Eur Radiol 2020 Jun 15;30(6):3310-3323. Epub 2020 Feb 15.

Department of Radiology, University of Cambridge School of Clinical Medicine, Box 218, Level 5, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.

Introduction: A systematic review and meta-analysis were performed to determine the diagnostic performance of dynamic contrast-enhanced computed tomography (DCE-CT) for the differentiation between malignant and benign pulmonary nodules.

Methods: Ovid MEDLINE and EMBASE were searched for studies published up to October 2018 on the diagnostic accuracy of DCE-CT for the characterisation of pulmonary nodules. For the index test, studies with a minimum of a pre- and post-contrast computed tomography scan were evaluated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00330-020-06661-8DOI Listing

A Veteran With a Solitary Pulmonary Nodule.

Fed Pract 2020 Jan;37(1):38-41

is a Hospitalist and the Director of Resident Education at VA Boston Healthcare System (VABHS) and an Assistant Professor of Medicine at Harvard University. He supervises the VA Boston Medical Forum chief resident case conferences. is a Medical Resident at the VABHS and Boston Medical Center. is a Resident at Boston University School of Medicine. is a Cardiology Fellow at Stritch School of Medicine in Maywood, Illinois. is a Pulmonary and Critical Care Physician at VABHS and Assistant Professor of Medicine at the Boston University School of Medicine. is a Physician of Pathology and Laboratory Medicine at VABHS and Assistant Professor of Pathology at Harvard Medical School. is a Infectious Disease Physician at VABHS and Assistant Professor of Medicine at Harvard Medical School.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010343PMC
January 2020

The multidisciplinary team plays an important role in the prediction of small solitary pulmonary nodules: a propensity-score-matching study.

Ann Transl Med 2019 Dec;7(23):740

Department of Oncology, The Second Xiangya Hospital, Central South University, Changsha 410011, China.

Background: According to guidelines, it is recommended that pulmonary nodules be discussed by a multidisciplinary team (MDT); however, the evidence for the effectiveness of MDT is sparse. To demonstrate the importance of the involvement of an MDT for the prediction of small solitary pulmonary nodules, we conducted this retrospective study.

Methods: The patient database of those who attended our MDT and the electronic medical record system of our hospital was used; we collected all the data from patients found with small solitary pulmonary nodules (≤2 cm), which were suspected as malignant and who received a resection of the nodules. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/atm.2019.11.125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990031PMC
December 2019

The combination of CTCs and CEA can help guide the management of patients with SPNs suspected of being lung cancer.

BMC Cancer 2020 Feb 10;20(1):106. Epub 2020 Feb 10.

Department of Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, 85Wujin Road, Shanghai, 200080, China.

Objective: Solitary pulmonary nodules (SPNs) is a common radiographic finding and require further evaluation because of the possibility of lung cancer. This study aimed to determine the sensitivity and specificity of circulating tumour cells (CTCs) as a marker for the diagnosis of SPNs and the integration of CTCs, carcinoembryonic antigen (CEA) and imaging findings to improve the sensitivity and specificity of diagnosis in patients with SPNs suspected of being lung cancer.

Method: For the serum biomarker assay, the concentration of CEA was measured by an automated electrochemiluminescence analyzer. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12885-020-6524-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011271PMC
February 2020

Olfactory neuroblastoma pulmonary metastasis presenting as a solitary pulmonary mass in an adult: A case report with pathologic correlation.

Radiol Case Rep 2020 Apr 20;15(4):330-333. Epub 2020 Jan 20.

Department of Pathology and Laboratory Medicine, University of North Carolina Hospitals, Women and Children Hospital, Chapel Hill, NC, USA.

Pulmonary metastasis of an esthesioneuroblastoma is uncommon. In this report, we present a case of an esthesioneuroblastoma pulmonary metastasis in an adult. A 39-year-old man treated with surgical resection of olfactory neuroblastoma was found to have a solitary pulmonary mass on a surveillance computed tomography scan performed 5 years after undergoing primary surgery and radiation treatment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.radcr.2019.12.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974704PMC

A multi-feature image retrieval scheme for pulmonary nodule diagnosis.

Medicine (Baltimore) 2020 Jan;99(4):e18724

School of Science and Engineering, Shandong University of Traditional Chinese Medicine.

Deep analysis of radiographic images can quantify the extent of intra-tumoral heterogeneity for personalized medicine.In this paper, we propose a novel content-based multi-feature image retrieval (CBMFIR) scheme to discriminate pulmonary nodules benign or malignant. Two types of features are applied to represent the pulmonary nodules. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000018724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004710PMC
January 2020