268 results match your criteria Solid Omental Tumors

Characterizing the tumor microenvironment of metastatic ovarian cancer by single-cell transcriptomics.

Cell Rep 2021 May;35(8):109165

Section of Genetic Medicine, Department of Medicine, University of Chicago, 5841 S. Maryland Avenue, Chicago, IL 60637, USA. Electronic address:

Understanding the cellular composition of the tumor microenvironment and the interactions of the cells is essential to the development of successful immunotherapies in cancer. We perform single-cell RNA sequencing (scRNA-seq) of 9,885 cells isolated from the omentum in 6 patients with ovarian cancer and identify 9 major cell types, including cancer, stromal, and immune cells. Transcriptional analysis of immune cells stratifies our patient samples into 2 groups: (1) high T cell infiltration (high T) and (2) low T cell infiltration (low T). Read More

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[A Case of Mature Teratoma in the Hepatoduodenal Ligament].

Gan To Kagaku Ryoho 2020 Dec;47(13):2239-2241

Dept. of Surgery, Hyogo Prefectural Nishinomiya Hospital.

A 60's woman was admitted to our hospital because of palpitations that occurred with exertion. Coronary angiography computed tomography(CT)of suspected angina detected a tumor in the pancreatic head region. Abdominal CT showed a poorly enhanced 40×32 mm solid tumor in the hepatoduodenal ligament that contained a fatty component and calcification. Read More

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December 2020

Clinicopathological and immunohistochemical study of 29 cases of solid-pseudopapillary neoplasms of the pancreas in patients under 20 years of age along with detailed review of literature.

Diagn Pathol 2020 Dec 9;15(1):139. Epub 2020 Dec 9.

Department of Pathology and Laboratory Medicine, Aga Khan University Hospital, Karachi, Pakistan.

Background: Pancreatic Solid Pseudopapillary Neoplasms (SPNs) are rare low-grade malignant tumors with a marked preponderance for young females. Objective was to describe the morphology, differential diagnosis, and prognosis of SPNs in patients under 20 years of age and present a detailed review of literature.

Methods: A total of 29 cases in patients under 20 years of age reported as SPN during the period January 2014 to December 2019, were included in the study. Read More

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December 2020

Borderline ovarian tumors: French guidelines from the CNGOF. Part 1. Epidemiology, biopathology, imaging and biomarkers.

J Gynecol Obstet Hum Reprod 2021 Jan 4;50(1):101965. Epub 2020 Nov 4.

Centre Clinico-Biologique d'AMP, Pôle Femmes - Parents- Enfants, AP-HM, Hôpital de La Conception, 147 Bd Baille, 13005 Marseille, France.

The incidence (rate per 100 000) of borderline ovarian tumors (BOTs) increases progressively with age, starting at 15-19 years and peaking at around 4.5 cases per 100 000 at an age of 55-59 years (LE3) with a median age of 46 years. The five year survival for FIGO stages I, II, III and IV is 99. Read More

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January 2021

Modulation of Immune Infiltration of Ovarian Cancer Tumor Microenvironment by Specific Subpopulations of Fibroblasts.

Cancers (Basel) 2020 Oct 29;12(11). Epub 2020 Oct 29.

Indiana University School of Medicine-Bloomington, Indiana University, Bloomington, IN 47405, USA.

Tumor immune infiltration plays a key role in the progression of solid tumors, including ovarian cancer, and immunotherapies are rapidly emerging as effective treatment modalities. However, the role of cancer-associated fibroblasts (CAFs), a predominant stromal constituent, in determining the tumor-immune microenvironment and modulating efficacy of immunotherapies remains poorly understood. We have conducted an extensive bioinformatic analysis of our and other publicly available ovarian cancer datasets (GSE137237, GSE132289 and GSE71340), to determine the correlation of fibroblast subtypes within the tumor microenvironment (TME) with the characteristics of tumor-immune infiltration. Read More

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October 2020

Unusual presentation of small bowel GIST: diffuse omental & mesenteric sarcomatosis.

J Surg Case Rep 2020 Sep 21;2020(9):rjaa341. Epub 2020 Sep 21.

Pathology Unit, "S. Pertini" Hospital, Rome, Italy.

Gastrointestinal stromal tumors (GISTs) represent ~1% of gastrointestinal (GI) tract neoplasms. Unusual presentation of a small bowel GIST with diffuse omental and mesenteric implants in a symptomatic patient is reported. CT scan in a 68-years-old woman showed multiple processes with solid density and colliquation areas in the abdominal cavity. Read More

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September 2020

Primary mixed large cell neuroendocrine and high grade serous carcinoma of the endometrium.

BMJ Case Rep 2020 Sep 2;13(9). Epub 2020 Sep 2.

Gynaecology Oncology, King Edward Memorial Hospital for Women Perth, Subiaco, Western Australia, Australia.

Endometrial large-cell neuroendocrine carcinoma admixed with a high-grade serous (HGS) adenocarcinoma is extremely rare with only one reported case in the literature. We present the second reported case in a 47-year-old woman who presented with abdominal pain, distension and loss of weight. On examination she had a fixed pelvic mass and vascular left vaginal mass. Read More

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September 2020

Preoperative 3D reconstruction images for paediatric tumours: Advantages and drawbacks.

Pediatr Blood Cancer 2021 01 22;68(1):e28670. Epub 2020 Aug 22.

Department of Visceral and Neonatal Paediatric Surgery, Sorbonne Université - APHP.6, Hôpital Armand Trousseau, Paris, France.

Rationale: Three-dimensional reconstruction (3DR) of preoperative images may improve the presurgical assessment of tumours prior to removal. We aimed to analyse the advantages and discrepancies of preoperative 3DR in paediatric tumours.

Methods: We conducted a prospective observational study from 2016 to 2019, including patients with thoraco-abdominal tumours having predictable surgical risks on preoperative images (encasement of vessels posing vascular risks, ie, neuroblastic and soft tissue tumours or parenchyma preservation of the invaded organ, ie, liver and kidney). Read More

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January 2021

A Report of a Rare Case of an Advanced Adult Granulosa Cell Tumor Initially Diagnosed as Primary Ovarian Melanoma.

Cureus 2020 May 1;12(5):e7921. Epub 2020 May 1.

Medical Oncology, Mohammed VI University Hospital, Oujda, MAR.

Ovarian granulosa cell tumors are rare gynecological cancers with favorable clinical evolution and survival outcomes. We report a new case of this presentation in a patient that was initially diagnosed as a bilateral primary melanoma of the ovary. The patient is a 51-year-old woman with a history of abdominal swelling and deterioration of her general conditions. Read More

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Peritoneal Carcinomatosis of Colorectal Origin in Cyclosporine Immunosuppressed Rats.

Gulf J Oncolog 2020 May;1(33):27-30

Surgical Research Laboratory, Saint Joseph University, Beirut, Lebanon.

Objective: We evaluate the seeding step of peritoneal carcinomatosis cancer as a surrogate for the role of the omentum in colorectal tumors.

Methods: The study included 5 groups of adult male Sprague Dawley rats: immunocompetent rats (group 1), immunosuppressed rats without omentectomy (group 2), immunosuppressed rats with omentectomy (group 3), immunosuppressed rats with omentectomy receiving NSAID (group 4), and immunosuppressed rats without omentectomy receiving NSAID (group 5). Except for group 1, the rats were immunosuppressed using cyclosporine orally at a dose of 25 mg/kg/day that was started 48 hours before tumor cell infiltration in the peritoneum. Read More

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Ultrasonographic findings and diagnosis of omental dedifferentiated liposarcoma: a case report.

J Rural Med 2020 Apr 1;15(2):68-72. Epub 2020 Apr 1.

Department of Gastroenterology, Gifu University Graduate School of Medicine, Japan.

Liposarcoma is one of the most common types of soft tissue sarcomas and can develop at any site, although omental liposarcoma is extremely rare. Omental liposarcoma has a poor prognosis because the diagnosis is difficult, until it presents as a large tumor causing severe noticeable clinical symptoms. A 51-year-old male with lower abdominal pain was referred to our clinic. Read More

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Tuberculosis and ovarian malignancy: Sometimes mimics, sometimes coexists.

J Obstet Gynaecol Res 2020 Jun 3;46(6):945-949. Epub 2020 Apr 3.

Department of Obstetrics & Gynaecology, All India Institute of Medical Sciences, Jodhpur, India.

Tuberculosis is a disease prevalent all over the world with India contributing to a larger share. Pulmonary tuberculosis presents with generalized symptoms of malaise, low grade fever and cough. On the other hand, genital tuberculosis presents with a variety of symptoms in each age group and is often underdiagnosed and missed. Read More

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Peritoneal metastasis in Stage IB1 adenocarcinoma cervix: A rare entity.

J Cancer Res Ther 2019 Oct-Dec;15(6):1415-1417

Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.

The presence of ovarian or peritoneal metastasis in early-stage cervical malignancy is a rare entity. It often poses a diagnostic challenge whether it is a synchronous primary tumor or a metastatic lesion. A 63-year-old postmenopausal woman presented with Stage 1B1 carcinoma cervix with ascites, and a 5. Read More

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Pulmonary and mediastinum metastasis of uterine leiomyoma: A case report.

Medicine (Baltimore) 2019 Dec;98(49):e18276

Department of pathology, Children's hospital of Hebei Province, Shijiazhuang, China.

Rationale: Pulmonary benign metastasizing leiomyoma (PBML) is rare, usually occurs in women who underwent hysterectomy during the reproductive years, and has no obvious clinical symptoms. A full understanding of the characteristics of PBML is important for its sequential treatment and prognosis.

Patient Concerns: In this report, a 36-year-old female patient with previous uterine leiomyoma who underwent 3 surgical resections of the uterus, bilateral fallopian tubes, and partial omentum was investigated. Read More

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December 2019

Highly differentiated follicular carcinoma of ovary: Use of imprint cytology at intraoperative consultation.

Diagn Cytopathol 2020 Apr 2;48(4):360-363. Epub 2019 Dec 2.

Department of pathology, Pennsylvania Hospital, University of Pennsylvania Health System, Philadelphia, Pennsylvania.

Highly differentiated follicular carcinoma of ovary (HDFCO) is a rare entity known to arise in struma ovarii. Clinical presentation and radiological features mimic other cystic ovarian neoplasm. Thus, intraoperative diagnosis of this entity can be challenging. Read More

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Subclassification of Multivisceral Resections for T4b Colon Cancer with Relevance for Postoperative Complications and Oncological Risks.

J Gastrointest Surg 2020 09 20;24(9):2113-2120. Epub 2019 Nov 20.

Department of Surgery, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands.

Background: Multivisceral resection for T4b colon cancer constitutes a heterogeneous group of surgical procedures. The purpose of this study was to explore clinically distinct categories of multivisceral resection, with subsequent correlation to postoperative complications and oncological outcomes.

Methods: In this multicenter cohort study, all consecutive patients without metastases who underwent multivisceral resection for pT4bN0-2M0 colon cancer between 2000 and 2014 were included. Read More

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September 2020

The role of preoperative imaging and tumor markers in predicting malignant ovarian masses in children.

Pediatr Surg Int 2020 Mar 7;36(3):333-339. Epub 2019 Nov 7.

Department of General Surgery, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai, 200040, China.

Purpose: To investigate the clinicopathololgic characteristics and the predicting value of preoperative imaging and tumor markers in children with ovarian masses.

Methods: Patients admitted in Shanghai children's hospital with ovary neoplasms between 2010.01 and 2015. Read More

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Spontaneous rupture of solid pseudopapillary tumor of pancreas: A case report and review of literature.

Medicine (Baltimore) 2019 Nov;98(44):e17554

Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University.

Introduction: Solid pseudopapillary tumors (SPT) account for 1% to 3% of all pancreatic tumors. They have low malignant potential with a favorable prognosis, and predominantly occur in young women. The pathogenesis and clinical behavior of SPT are still uncertain. Read More

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November 2019

Gastrointestinal Stromal Tumor (GIST) from esophagus to anorectum - diagnosis, response evaluation and surveillance on computed tomography (CT) scan.

Indian J Radiol Imaging 2019 Apr-Jun;29(2):133-140

Department of Surgical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Gastrointestinal stromal tumor (GIST) are the most common non epithelial tumor of the gastrointestinal (GI) tract. They arise from interstitial cells of Cajal present in the myenteric plexus. They can also arise outside the GI tract from mesentery, retro peritoneum and omentum. Read More

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Roles of omental and bone marrow adipocytes in tumor biology.

Adipocyte 2019 12;8(1):304-317

a Department of Pathology, Yonsei University College of Medicine , Seoul , South Korea.

Accumulating evidence highlights the importance of interactions between tumour cells and stromal cells for tumour initiation, progression, and metastasis. In tumours that contain adipocyte in their stroma, adipocytes contribute to modification of tumour microenvironment and affect metabolism of tumour and tumour progression by production of cytokines and adipokines from the lipids. The omentum and bone marrow (BM) are highly adipocyte-rich and are also common metastatic and primary tumour developmental sites. Read More

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December 2019

Primary hepatic melanoma: A case report of computed tomography and magnetic resonance imaging findings.

Medicine (Baltimore) 2019 Jun;98(25):e16165

Department of Radiology.

Rationale: Malignant melanoma predominantly develops in middle-aged and older adults, most commonly occurring on the skin and rarely on internal organs. Malignant melanoma originating in the liver is extremely rare. Imaging findings of primary hepatic melanoma (PHM) are scarce in relevant literature. Read More

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Case of leiomyosarcoma arising from subserosal leiomyoma.

J Obstet Gynaecol Res 2019 Sep 19;45(9):1944-1947. Epub 2019 Jun 19.

Department of Obstetrics and Gynecology, Juntendo University Faculty of Medicine, Tokyo, Japan.

Uterine leiomyosarcoma (LMS) is a rare tumor. It has not been established if these tumors arise de novo or from pre-existing leiomyomas (LM). We report a case herein of LMS arising from a subserosal LM. Read More

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September 2019

Mixed endometrioid and clear cell carcinoma arising from laparoscopic trocar site endometriosis.

J Obstet Gynaecol Res 2019 Aug 10;45(8):1613-1618. Epub 2019 Jun 10.

Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo, Tokyo, Japan.

Laparoscopic port site endometriosis is less common in abdominal wall endometriosis, and malignant transformation of abdominal wall endometriosis is rare. We reported a case of mixed endometrioid and clear cell carcinoma arising from port site endometriosis. The patient was a 49-year-old woman with a history of laparoscopic excision of ovarian endometrioma. Read More

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Managing peritoneal involvement in children and young people with rhabdomyosarcoma: A single-center experience from the United Kingdom.

Pediatr Blood Cancer 2019 09 27;66(9):e27805. Epub 2019 May 27.

Children and Young People's Unit, Royal Marsden Hospital, Sutton, United Kingdom.

We describe our experience in managing nine children and adolescents with rhabdomyosarcoma (RMS) and peritoneal involvement. The radiological pattern of peritoneal involvement was diverse from only ascites to solid peritoneal mass/omental caking. Treatment included systemic chemotherapy in all, surgery in three, and radiotherapy in eight. Read More

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September 2019

Desmoplastic small round cell tumor of the parotid gland-report of a rare case and a review of the literature.

Diagn Pathol 2019 May 18;14(1):43. Epub 2019 May 18.

Department of Surgical Pathology, Hokkaido University Hospital, N14W4, Kita-ku, Sapporo, Japan.

Background: Desmoplastic small round cell tumor (DSRCT) is a rare soft tissue tumor that generally involves the retroperitoneum, pelvis, omentum and mesentery in younger patients. However, extra-abdominal DSRCT is very rare.

Case Presentation: A 49-year-old Japanese man noticed a mass in the right parotid gland. Read More

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Measuring response to neoadjuvant chemotherapy in high-grade serous tubo-ovarian carcinoma: an analysis of the correlation between CT imaging and chemotherapy response score.

Int J Gynecol Cancer 2019 May 15. Epub 2019 May 15.

Oncology, Bendat Family Comprehensive Cancer Centre, St John of God Hospital, Subiaco, Subiaco, Western Australia, Australia.

Introduction: Response to neoadjuvant chemotherapy is measured by CT and the decision to proceed with interval surgery is made on the radiological response after two or three cycles of therapy. The Chemotherapy Response Score grades histological tumor regression in omental metastases resected at interval surgery and is associated with progression-free survival and overall survival. It is uncertain whether radiological response is associated with prognosis and whether radiological response predicts Chemotherapy Response Score. Read More

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Leyomiomatosis peritonealis disseminata associated with ovarian endometriosis in a patient submitted to hysteroscopic myomectomy.

Fertil Steril 2019 06 25;111(6):1259-1261. Epub 2019 Apr 25.

Gynaecology and Human Reproduction Physiopathology, Department of Obstetrics and Gynecology, DIMEC, S.Orsola Hospital, University of Bologna, Bologna, Italy.

Objective: To describe laparoscopic management of a case of leyomiomatosis peritonealis disseminata associated with ovarian endometriosis.

Design: Surgical video article.

Setting: Academic hospital. Read More

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Posttransplant epithelioid inflammatory myofibroblastic sarcoma: A case report.

Indian J Pathol Microbiol 2019 Apr-Jun;62(2):303-305

Department of Histopathology, Apollo Hospital, New Delhi, India.

Epithelioid inflammatory myofibroblastic sarcoma (EIMS) is a rare entity and a novel variant of inflammatory myofibroblastic tumor (IMT), usually seen in children and nonsmoking young adults. Their occurrence in a posttransplant setting is still rare. These tumors are characterized by prominent epithelioid morphology, large histiocytoid "Reed Sternberg"-like cell, unique pattern of ALK immuno-reactivity, and aggressive clinical behavior. Read More

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Ovarian Mucinous Carcinoma with Mural Carcinosarcomatous Components in a Prepubertal Girl.

J Pediatr Adolesc Gynecol 2019 Aug 6;32(4):436-439. Epub 2019 Apr 6.

Department of Obstetrics and Gynecology, Dokkyo Medical University Saitama Medical Center, Koshigaya, Japan.

Background: Epithelial ovarian cancer development before menarche is extremely rare.

Case: We report a prepubertal girl who developed ovarian mucinous carcinoma with mural carcinosarcomatous components.

Summary And Conclusion: Magnetic resonance imaging showed a polycystic mass with solid components. Read More

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