25,842 results match your criteria Snake Envenomation Overview
Med Mycol 2018 Dec 6. Epub 2018 Dec 6.
Mycology Unit, Facultat de Medicina i Ciències de la Salut and IISPV, University Rovira i Virgili, Reus, Spain.
We report several cases of fungal infections in snakes associated with a new species within the genus Paranannizziopsis. Three juvenile Wagler's vipers (Tropidolaemus wagleri) presented with skin abnormalities or ulcerative dermatitis, and two snakes died. Histologic examination of skin from the living viper revealed hyperplastic, hyperkeratotic, and crusting epidermitis with intralesional fungal elements. Read More
Zoolog Sci 2018 Dec;35(6):483-486
1 Wildlife Research Center, Kyoto University, 2-24 Tanaka Sekiden-cho, Sakyo, Kyoto 606-8203, Japan.
Fully aquatic adaptation generally leads amniotes to change sensory modalities drastically. Terrestrial snakes rely heavily on chemical cues to locate and recognize prey, but little is known about how sea snakes find prey fishes underwater. Sea snakes of the genus Hydrophis are fish-eating marine elapids which adapted from land to water approximately 5-10 million years ago. Read More
Toxins (Basel) 2018 Dec 4;10(12). Epub 2018 Dec 4.
Venom Evolution Lab, School of Biological Sciences, University of Queensland, St Lucia, QLD 4072, Australia.
Snakebite is a global tropical disease that has long had huge implications for human health and well-being. Despite its long-standing medical importance, it has been the most neglected of tropical diseases. Reflective of this is that many aspects of the pathology have been underinvestigated. Read More
Genomics 2018 Nov 30. Epub 2018 Nov 30.
CIIMAR/CIMAR, Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos, s/n, Porto 4450-208, Portugal; Department of Biology, University of Porto, Rua do Campo Alegre, s/n, Porto 4169-007, Portugal. Electronic address:
The Harderian gland is a cephalic structure, widely distributed among vertebrates. In snakes, the Harderian gland is anatomically connected to the vomeronasal organ via the nasolacrimal duct, and in some species can be larger than the eyes. The function of the Harderian gland remains elusive, but it has been proposed to play a role in the production of saliva, pheromones, thermoregulatory lipids and growth factors, among others. Read More
Int J Biol Macromol 2018 Nov 30. Epub 2018 Nov 30.
Pharmaceutical College, Guangxi Medical University, Nanning, China. Electronic address:
Natrin, a new member of the cysteine-rich secretory protein (CRISP) family purified from the snake venom of Naja naja atra, has been demonstrated to have anticancer activity. However, the underlying molecular mechanisms need further elucidation. In this study, MTT was used to evaluate cell viability. Read More
PLoS Negl Trop Dis 2018 Dec 3;12(12):e0007014. Epub 2018 Dec 3.
Department of Emergency Medicine, Chang Gung Memorial Hospital, Tao-Yuan, Taiwan.
Taiwan is an island located in the south Pacific, a subtropical region that is home to 61 species of snakes. Of these snakes, four species-Trimeresurus stejnegeri, Protobothrops mucrosquamatus, Bungarus multicinctus and Naja atra-account for more than 90% of clinical envenomation cases. Currently, there are two types of bivalent antivenom: hemorrhagic antivenom against the venom of T. Read More
J Cell Biochem 2018 Dec 2. Epub 2018 Dec 2.
Department of Studies in Biochemistry, University of Mysore, Manasagangothri, Mysuru, India.
Echis carinatus envenomation leads to severe tissue necrosis at the bitten site by releasing DNA from immune cells that blocks the blood flow. An earlier report has shown that exogenous DNase 1 offers protection against such severe local tissue necrosis. Tricosanthus tricuspidata is a medicinal plant and the paste prepared from its leaves has been used extensively for the treatment of snakebite-induced tissue necrosis. Read More
Eur J Neurosci 2018 Dec 1. Epub 2018 Dec 1.
Institute for Biomagnetism and Biosignal Analysis, University of Muenster, D-48149, Muenster, Germany.
Biased motivated attention towards phobia-relevant pictures is a typical finding in specific phobia. In the visual system, the allocation of motivated attention is indexed by two event-related potential components - the Early Posterior Negativity and the Late Positive Potential. Enhanced Early Posterior Negativity and Late Positive Potential amplitudes are reliably observed in specific phobia such as, for instance, snake, spider or blood-injection-injury phobia and to some extent also in dental phobia. Read More
Zookeys 2018 19(797):117-160. Epub 2018 Nov 19.
Universidade Federal de Viçosa, Departamento de Biologia Animal, Avenida P.H. Rolfs, S/N, Campus Universitário, CEP 36571-000, Viçosa, MG, Brazil.
The Serra da Mantiqueira is one of the least inventoried physiographic areas of southeastern Brazil. There is great potential for detection of endemic species for which little or nothing is known about basic aspects of natural history. The Parque Estadual da Serra do Papagaio (PESP) within the Serra da Mantiqueira is an area of extreme biological importance because it houses mixed formations of grasslands, ombrophilous forests, and enclaves of Araucaria forests (mixed ombrophilous forest). Read More
J Biol Chem 2018 Nov 30. Epub 2018 Nov 30.
Faculty of Pharmaceutical Sciences,, Hokkaido University, Japan.
Venomous snakes have endogenous proteins that neutralize the toxicity of their venom components. We previously identified five small serum proteins (SSP-1-SSP-5) from a highly venomous snake belonging to the family Viperidae as inhibitors of various toxins from snake venom. The endogenous inhibitors belong to the prostate secretory protein of 94 amino acids (PSP94) family. Read More
Vet Rec 2018 Dec;183(21):661-662
Animal Protection Agency, Werks Central, 15-17 Middle Street, Brighton BN1 1AL.
Vet Rec 2018 Dec;183(21):661
The Independent Ad Hoc Scientific Group on Snake Welfare, c/o Riverside House, River Lawn Road, Tonbridge TN9 1EP.
J Comp Pathol 2018 Nov 28. Epub 2018 Nov 28.
University of São Paulo, School of Veterinary Medicine and Animal Science, Department of Pathology, Laboratory of Wildlife Comparative Pathology, Av. Orlando Marques de Paiva 87, São Paulo, Brazil.
Congenital malformations (CMs) or developmental abnormalities are pathological processes defined as morphological defects that originate during embryonic stages. A wide variety of CMs is observed in reptiles, most of which are incompatible with normal life. Characterization of CMs and their pathogenesis are of great importance for the conservation of reptiles, including neotropical viperids (NVs). Read More
Toxicol Lett 2018 Nov 28. Epub 2018 Nov 28.
FaunaVet Wildlife Consultancy, Glass House Mountains, QLD, 4518, Australia. Electronic address:
Due to their potent coagulotoxicity, Australian elapid venoms are unique relative to non-Australian members of the Elapidae snake family. The majority of Australian elapids possess potent procoagulant venom, while only a few species have been identified as possessing anticoagulant venoms. The majority of research to-date has concentrated on large species with range distributions overlapping major city centres, such as brown snakes (Pseudonaja spp. Read More
Anal Chem 2018 Dec 3. Epub 2018 Dec 3.
Tools that provide absolute quantification of biomolecules, particularly of proteins and their post-translational modifications, without needing suitable specific standards, are urgently demanded nowadays. To this end, we have herein most significantly advanced the recently introduced strategy based on CH4 addition to the plasma for absolute quantification of biomolecules with HPLC-ICP-MS. Addition of CO2 has been optimized and finally selected as a safer, and more efficient quantitative strategy, able to provide constant (< 6% error) signal response factor for the six elements assayed (S, P, As, Se, Br, I) under compromise conditions. Read More
J Morphol 2018 Dec 5. Epub 2018 Dec 5.
Department of Animal Histology and Embryology, University of Silesia in Katowice, Poland.
Differentiation of the pancreatic islets in grass snake Natrix natrix embryos, was analyzed using light, transmission electron microscopy, and immuno-gold labeling. The study focuses on the origin of islets, mode of islet formation, and cell arrangement within islets. Two waves of pancreatic islet formation in grass snake embryos were described. Read More
Sci Rep 2018 Dec 4;8(1):17622. Epub 2018 Dec 4.
Department of Biology, University of Central Florida, 4110 Libra Drive, Orlando, FL, 32816, USA.
Snake venoms represent an enriched system for investigating the evolutionary processes that lead to complex and dynamic trophic adaptations. It has long been hypothesized that natural selection may drive geographic variation in venom composition, yet previous studies have lacked the population genetic context to examine these patterns. We leverage range-wide sampling of Mojave Rattlesnakes (Crotalus scutulatus) and use a combination of venom, morphological, phylogenetic, population genetic, and environmental data to characterize the striking dichotomy of neurotoxic (Type A) and hemorrhagic (Type B) venoms throughout the range of this species. Read More
Toxins (Basel) 2018 Dec 3;10(12). Epub 2018 Dec 3.
Center of Research Excellence on Therapeutic Proteins and Antibody Engineering, Department of Parasitology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Snake venom-metalloproteinases (SVMPs) are the primary factors that disturb hemostasis and cause hemorrhage in the venomous snake bitten subjects. Kaouthiagin is a unique SVMP that binds and cleaves von Willebrand factor (vWF) at a specific peptide bond leading to inhibition of platelet aggregation, which enhances the hemorrhage. Kaouthiagin is a low abundant venom component of Thai cobra (); thus, most horse-derived antivenins used for cobra bite treatment do not contain adequate anti-kaouthiagin. Read More
Toxins (Basel) 2018 Dec 1;10(12). Epub 2018 Dec 1.
Facultad de Ciencias Biológicas, Universidad Juárez del Estado de Durango, Av. Universidad s/n. Fracc. Filadelfia, C.P. 35010 Gómez Palacio, Dgo., Mexico.
Ontogenetic changes in venom composition have important ecological implications due the relevance of venom in prey acquisition and defense. Additionally, intraspecific venom variation has direct medical consequences for the treatment of snakebite. However, ontogenetic changes are not well documented in most species. Read More
Med J Armed Forces India 2011 Apr 21;67(2):131-137. Epub 2011 Jul 21.
Background: Poisoning and envenomation are common health hazards for the Armed Forces personnel. This study was undertaken to analyse the problem in a systematic way so that meaningful data can be generated for policy formulation regarding treatment of such cases.
Methods: Data were collected from various service hospitals on a 16-point format of all patients treated for any kind of poisoning or envenomation. Read More
J Therm Biol 2018 Dec 15;78:401-414. Epub 2018 Nov 15.
Departamento de Ecologia, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil.
In recent decades, changes in climate have caused impacts on natural and human systems on all continents and across the oceans and many species have shifted their geographic ranges, seasonal activities, migration patterns, abundances and interactions in response to these changes. Projections of future climate change are uncertain, but the Earth's warming is likely to exceed 4.8 °C by the end of 21th century. Read More
J Therm Biol 2018 Dec 7;78:36-41. Epub 2018 Aug 7.
Institute of Environmental Sciences, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, Poland.
Reactive oxygen species (ROS) are inescapable byproducts of energy metabolism and may cause costly damage to biomolecules. Organisms have evolved different means to counter oxidative stress, such as modulation of ROS production, neutralization of produced ROS through free radical scavenging and the repair or removal of the damaged structures. A positive relationship between metabolic rate and ROS production is commonly expected, but the oxidative burden of aerobic metabolism remains poorly understood. Read More
J Venom Anim Toxins Incl Trop Dis 2018 23;24:33. Epub 2018 Nov 23.
1Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo (FCFRP-USP), Avenida do Café, s/n, B. Monte Alegre, Ribeirão Preto, SP 14040-903 Brazil.
Background: Snake venom phospholipases A (PLAs) have been reported to induce myotoxic, neurotoxic, hemolytic, edematogenic, cytotoxic and proinflammatory effects. This work aimed at the isolation and functional characterization of a PLA isolated from venom, named BJ-PLA-I.
Methods And Results: For its purification, three consecutive chromatographic steps were used (Sephacryl S-200, Source 15Q and Mono Q 5/50 GL). Read More
J Venom Anim Toxins Incl Trop Dis 2018 22;24:32. Epub 2018 Nov 22.
1Department of Physics and Chemistry, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Av. do Café s/n°, Monte Alegre, Ribeirão Preto, SP 14040-903 Brazil.
Background: (Lmr) is the largest venomous snake in Latin America and its venom contains mainly enzymatic components, such as serine and metalloproteases, L-amino acid oxidase and phospholipases A. Metalloproteases comprise a large group of zinc-dependent proteases that cleave basement membrane components such as fibronectin, laminin and collagen type IV. These enzymes are responsible for local and systemic changes, including haemorrhage, myonecrosis and inflammation. Read More
Med Phys J 1813 Feb;29(168):120-125
Civil Surgeon, Chittagong.
Med Phys J 1810 Nov;24(141):391-402
Med Phys J 1805 Dec;14(82):524-525
Med Phys J 1804 Apr;11(62):332-334
Charleston, America.
Med Phys J 1804 Apr;11(62):334-337
Philadelphia.
Microb Pathog 2018 Nov 27;127:7-11. Epub 2018 Nov 27.
Department of Molecular Biology, School of Biological Sciences, Madurai Kamaraj University, 625 021, India. Electronic address:
Aeromonas hydrophila is a major bacterial fish pathogen which causes economic losses in the aquaculture. The study determined the Letha Dose (LD) of A. hydrophila Ah17 strain (isolated from EUS infected Channa striata) in C. Read More
Toxins (Basel) 2018 Nov 28;10(12). Epub 2018 Nov 28.
Laboratório de Toxinologia, Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto 14040-903, Brazil.
Snake venom serine proteases (SVSPs) are enzymes that are capable of interfering in various parts of the blood coagulation cascade, which makes them interesting candidates for the development of new therapeutic drugs. Herein, we isolated and characterized Moojase, a potent coagulant enzyme from snake venom. The toxin was isolated from the crude venom using a two-step chromatographic procedure. Read More
J Clin Microbiol 2018 Nov 28. Epub 2018 Nov 28.
Zoological Pathology Program, Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Brookfield, Illinois, USA.
The fungal order Onygenales includes many pathogens of humans and animals, and recent studies have shown some onygenalean fungi to be significant emerging pathogens of reptiles. Although many of these fungi have similar morphological features in histologic tissue sections, recent molecular analyses have revealed a genetically complex and diverse group of reptile pathogens comprising several genera, most notably , , and Infections by members of these genera have been previously reported in a variety of reptile species, including crocodilians, lizards, snakes, and tuataras with negative impacts on conservation efforts for some reptiles. Despite the well-documented pathogenicity of these fungi in all other extant reptile lineages, infection has not yet been reported in aquatic turtles. Read More
Cogn Emot 2018 Nov 28:1-12. Epub 2018 Nov 28.
b Baskent University , Department of Psychology , Ankara , Turkey.
Popular culture has many examples of evil characters having vertically pupilled eyes. Humans have a long evolutionary history of rivalry with snakes and their visual systems were evolved to rapidly detect snakes and snake-related cues. Considering such evolutionary background, we hypothesised that humans would perceive vertical pupils, which are characteristics of ambush predators including some of the snakes, as threatening. Read More
Trop Doct 2018 Nov 28:49475518814019. Epub 2018 Nov 28.
Department of General Medicine, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.
Cardiotoxicity in snake envenomation has not been adequately explored in the literature. This retrospective, observational study analysed clinical profiles and cardiovascular effects (CVE), with associated outcomes, in snake envenomation. Thirty-four patients were recruited between April 2014 and October 2017. Read More
Zootaxa 2018 Nov 28;4526(1):71-83. Epub 2018 Nov 28.
California Academy of Sciences, San Francisco, California 94118-4503, USA..
Two new species of ophichthid eels, subfamily Ophichthinae, are described and illustrated from specimens collected from Myanmar by the R/V Dr. Fridtjof Nansen. Included are: Ophichthus nansen sp. Read More
Zootaxa 2018 Oct 18;4500(4):543-552. Epub 2018 Oct 18.
Department of Parasitology, School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, 4072, Australia..
We establish two new monotypic genera, Robertsicus n. gen. and Archaeocroton n. Read More
Zootaxa 2018 Nov 5;4514(1):126-136. Epub 2018 Nov 5.
Help Earth, 16, RNC Path, Lachitnagar, Guwahati 781007, Assam, India Department of Zoology, Gauhati University, Jalukbari, Guwahati 781014. Assam, India.
We sampled snakes of the genus Xenochrophis from across Northeast India. The snakes were evaluated for both morphological and molecular parameters. Phylogenetic relationship was reconstructed using mitochondrial genes (Cytb, 12s rRNA, ND4). Read More
Zootaxa 2018 Nov 5;4514(1):53-64. Epub 2018 Nov 5.
School of Biological Sciences, Universiti Sains Malaysia, 11800 Minden, Penang, Malaysia..
The taxonomic position of the rare Selangor Mud Snake (Raclitia indica) Gray to other species of homalopsids has remained uncertain due to the scarcity of specimens in collections and the lack of genetic material for comparison. Here we report the first molecular phylogenetic examination of this species based on recently acquired material. The study recovered R. Read More
Med Vet Entomol 2018 Nov 28. Epub 2018 Nov 28.
Laboratório de Hantaviroses e Rickettsioses, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil.
Knowledge about ticks (Acari) and screening of ticks parasitizing various hosts are necessary to understand the epidemiology of tick-borne pathogens. The objective of this study was to investigate tick infestations on snakes (Reptilia: Squamata: Serpentes) arriving at the serpentarium at the Institute Vital Brazil, Rio de Janeiro. Some of the identified ticks were individually tested for the presence of bacteria of the genera Rickettsia (Rickettsiales: Rickettsiaceae), Borrelia (Spirochaetales: Spirochaetaceae), Coxiella (Legionellales: Coxiellaceae), Bartonella (Rhizobiales: Bartonellaceae), Ehrlichia (Rickettsiales: Anaplasmataceae), Anaplasma (Rickettsiales: Anaplasmataceae), and Apicomplexa protozoa of the genera Babesia (Piroplasmida: Babesiidae) and Hepatozoon (Eucoccidiorida: Hepatozoidae). Read More
Aust Vet J 2018 Dec;96(12):481-486
Avian Reptile and Exotic Pet Hospital, School of Veterinary Science, University of Sydney, Camden, 2570, New South Wales, Australia.
Case Report: A 7-year-old male diamond python (Morelia spilota spilota) presented with a 2-month history of anorexia and a discrete intracoelomic mass, approximately 15 cm in length, located 90 cm from the head and approximately two-thirds of the snout to vent length. Physical examination determined the mass was likely to be stomach, testes or the right kidney. Radiographs showed a soft tissue opacity mass in the region of the stomach; fine needle aspirate demonstrated cellular debris admixed with bacteria and degenerate heterophils. Read More
Aust Vet J 2018 Dec;96(12):471-472
Biotechniques 2018 Dec;65(6):339-345
School of Biological Sciences, University of Northern Colorado, 501 20th Street, Greeley, CO 80639-0017, USA.
DNA barcoding is a simple technique used to develop a large-scale system of classification that is broadly applicable across a wide variety of taxa. DNA-based analysis of snake venoms can provide a system of classification independent of currently accepted taxonomic relationships by generating DNA barcodes specific to each venom sample. DNA purification from dried snake venoms has previously required large amounts of starting material, has resulted in low yields and inconsistent amplification, and was possible with front-fanged snakes only. Read More
Nat Prod Res 2018 Nov 26:1-4. Epub 2018 Nov 26.
a Phytochemistry and Phytopharmacology Division , Jawaharlal Nehru Tropical Botanic Garden and Research Institute , Thiruvananthapuram , Kerala , India.
Humboldtia unijuga Bedd., endemic to Agasthyamala in Western Ghats in India, is traditionally used by local Kani tribes for chicken pox, head ache and snake bite. This study reports the isolation of erythrodiol-3-acetate (HU-1) and 2,4-di-tert-butylphenol (HU-2) from H. Read More
Zoo Biol 2018 Nov 26. Epub 2018 Nov 26.
Zoo Atlanta, Atlanta, Georgia.
Many husbandry routines in zoo herpetology are based on tradition, authoritarianism, anecdote, or speculation. However, relatively few empirical studies underlie many very common practices. We compared growth rates among littermates of Boa constrictor raised under two feeding regimes that were identical in terms of the mass of food ingested, but differed in weekly versus bi-weekly schedules. Read More
R Soc Open Sci 2018 Oct 24;5(10):181070. Epub 2018 Oct 24.
Centre for Ecology and Conservation, University of Exeter, Penryn TR10 9FE, UK.
Nature is composed of self-propelled, animate agents and inanimate objects. Laboratory studies have shown that human infants and a few species discriminate between animate and inanimate objects. This ability is assumed to have evolved to support social cognition and filial imprinting, but its ecological role for wild animals has never been examined. Read More
R Soc Open Sci 2018 Oct 31;5(10):180136. Epub 2018 Oct 31.
Institute for Land, Water and Society, School of Environmental Sciences, Charles Sturt University, Albury, New South Wales 2640, Australia.
Invasive mammalian predators are linked to terrestrial vertebrate extinctions worldwide. Prey naïveté may explain the large impact invasive predators have on native prey; prey may fail to detect and react appropriately to the cues of novel predators, which results in high levels of depredation. In Australia, the feral cat () and the red fox () are implicated in more than 30 animal extinctions and the naïveté of native prey is often used to explain this high extinction rate. Read More
J Toxicol 2018 24;2018:6940798. Epub 2018 Oct 24.
Department of Wildlife Management and Ecotourism, Katima Mulilo Campus, Faculty of Agriculture and Natural Resources, University of Namibia, P. Bag 1096, Ngweze, Katima Mulilo, Namibia.
This study was designed to investigate the cytotoxicity and haemotoxicity of the Western barred (zebra) spitting cobra () venom to help explain atypical and inconsistent reports on syndromes by Namibian physicians treating victims of human ophidian accidents. Freeze-dried venom milked from adult zebra snakes was dissolved in phosphate buffered saline (PBS) for use in this study. Haemorrhagic and necrotic activity of venom were studied in New Zealand albino rabbits. Read More
Toxicon 2018 Nov 22. Epub 2018 Nov 22.
National Institute of Chemical Physics and Biophysics, Trummi 23A-3, 12617, Tallinn, Estonia.
The isolation and characterization of individual snake venom components is important for a deeper understanding of the pathophysiology of envenomations, for improving the therapeutic procedures of patients, and it also opens possibilities for the discovery of novel toxins that might be useful as tools for understanding cellular and molecular processes. This review provides a summary of the different toxins that have been isolated and characterized from the venoms of Vipera lebetina (Macrovipera lebetina) subspecies Macrovipera lebetina cernovi, Macrovipera lebetina lebetina, Macrovipera lebetina obtusa, Macrovipera lebetina transmediterranea, Macrovipera lebetina turanica, the snake species causing the majority of human envenomings in Central Asia (Middle East) and North Africa. The venoms of these snakes contain proteins belonging to different families: Zn- metalloproteinases, serine proteinases, L-amino acid oxidase, 5`-nucleotidase, phosphodiesterase, phosphomonoesterase, nucleases, hyaluronidase, phospholipase A2, C-type lectin-like protein, disintegrin, DC-fragment, cystein-rich secretory protein, proteinase inhibitors, nerve growth factor (NGF), vascular endothelial growth factor (VEGF), low molecular weight peptides. Read More
Toxicol In Vitro 2018 Nov 22;55:62-74. Epub 2018 Nov 22.
Venom Evolution Lab, School of Biological Sciences, University of Queensland, St Lucia, QLD 4072, Australia. Electronic address:
Venom can affect any part of the body reachable via the bloodstream. Toxins which specifically act upon the coagulation cascade do so either by anticoagulant or procoagulant mechanisms. Here we investigated the coagulotoxic effects of six species within the medically important pit viper genus Protobothrops (Habu) from the Chinese mainland and Japanese islands, a genus known to produce hemorrhagic shock in envenomed patients. Read More
Toxicon 2018 Nov 22;157:93-100. Epub 2018 Nov 22.
Departamento de Microbiologia, Instituto Aggeu Magalhães (IAM-FIOCRUZ), Av. Professor Moraes Rego s/n, 50670-420, Recife, Brazil.
Lectins are carbohydrate-binding proteins that play important roles in the immune system. Under specific conditions, lectins can form amyloids, proteinaceous aggregates rich in cross β-strand structures. A Ca-dependent lectin, isolated from Bothrops leucurus snake venom (BLL) has demonstrated relevant biological activities such as antibacterial and antitumor activity. Read More