10,597 results match your criteria Smear test


Detection of splenic microabscesses with ultrasound as a marker for extrapulmonary tuberculosis in patients with HIV: A systematic review.

S Afr Med J 2019 Jul 26;109(8):570-576. Epub 2019 Jul 26.

Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass, USA.

Background: In 2015, 1.2 million new cases of tuberculosis (TB) were diagnosed in patients with HIV. Diagnostic limitations and resource shortages in endemic areas can delay diagnosis and treatment, particularly with extrapulmonary TB (EPTB). Read More

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http://dx.doi.org/10.7196/SAMJ.2019.v109i8.13783DOI Listing

Women's experiences after abnormal Pap smear results: a qualitative study.

J Psychosom Obstet Gynaecol 2019 Aug 27:1-8. Epub 2019 Aug 27.

Midwifery Department, Health Science Faculty, Manisa Celal Bayar University , Manisa , Turkey.

Abnormal Pap smear result means there have been cell changes on the cervix but are not cancer. Women with abnormal test result may be affected from this situation. What do women with abnormal Pap smear results experience from a biopsychosocial perspective? This study aimed to explore the experiences of women with abnormal Pap smear results according to the biopsychosocial model. Read More

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http://dx.doi.org/10.1080/0167482X.2019.1657090DOI Listing
August 2019
1 Read

Associations of health belief and health literacy with Pap smear practice among Asian immigrant women.

Eur J Oncol Nurs 2019 Oct 6;42:63-68. Epub 2019 Aug 6.

College of Nursing, Gachon University, 191 Hambakmoero, Yeonsu-gu, Incheon, 21936, Republic of Korea. Electronic address:

Purpose: To examine associations of health belief and health literacy with Pap smear practice among Asian immigrant women in South Korea.

Methods: This study used a descriptive, cross-sectional study design. A survey was conducted among 196 migrant women who were married to South Korean men, using a questionnaire translated into English, Chinese, Vietnamese, and Korean. Read More

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http://dx.doi.org/10.1016/j.ejon.2019.08.003DOI Listing
October 2019
4 Reads

Influence of Trigonella foenum graecum seed extract as root canal irrigation agent on root surfaces: A scanning electron microscope/energy dispersive X-ray analysis study.

Microsc Res Tech 2019 Dec 24;82(12):1975-1981. Epub 2019 Aug 24.

Faculty of Dentistry, Department of Endodontics, Katip Çelebi University, İzmir, Turkey.

The purpose of this in vitro study was to investigate the effect of Trigonella foenum graecum seed extract (TFGSE) as a root canal irrigation agent on the surface of instrumented root canals and on changes in the mineral contents of the root dentin. A total of 90 extracted human mature maxillary central incisor teeth with a single root and without root resorption were selected. The specimens were subdivided into five groups according to irrigation protocol groups G0: distilled water (n = 15): G1: Sodium hypochlorite (5. Read More

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http://dx.doi.org/10.1002/jemt.23366DOI Listing
December 2019

Cartridge based nucleic acid amplification test is superior in diagnosing lymphnode tuberculosis.

Indian J Tuberc 2019 Jul 17;66(3):402-406. Epub 2018 May 17.

RBIPMT, Delhi, India.

Background: The role of Cartridge based Nucleic Acid Amplification test (CBNAAT) in the diagnosis of lymphnode TB which helps in reducing the mortality and morbidity by early identification and initiating treatment at the earliest. Also helps in identify the drug resistance among tubercular lymphnodes cases.

Patients And Methods: A prospective clinical study was performed in 101 suspected lymph node tuberculosis patients. Read More

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http://dx.doi.org/10.1016/j.ijtb.2018.04.001DOI Listing
July 2019
1 Read

Clinical profiles of early and tuberculosis-related mortality in South Korea between 2015 and 2017: a cross-sectional study.

BMC Infect Dis 2019 Aug 22;19(1):735. Epub 2019 Aug 22.

Division of Pulmonary Medicine, Department of Internal Medicine, Dankook University College of Medicine, 119 Dandae-ro, Dongnam-gu, Cheonan, 31116, Republic of Korea.

Background: Although the incidence of tuberculosis (TB) has decreased in South Korea, the mortality rate remains high. TB mortality is a key indicator for TB control interventions. The purpose of this study was to assess early and TB-related mortality during anti-TB treatment and describe the associated clinical characteristics. Read More

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http://dx.doi.org/10.1186/s12879-019-4365-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704578PMC
August 2019
2 Reads
2.613 Impact Factor

Evaluation of Smear Layer Removal Using Different Irrigation Methods In Root Canals.

Eur J Prosthodont Restor Dent 2019 Aug 29;27(3):97-102. Epub 2019 Aug 29.

University of Zurich, Division of Dental Biomaterials, Center for Dental and Oral Medicine, Clinic for Fixed and Removable Prosthodontics and Dental Materials Science, Zurich, Switzerland.

This study evaluated different irrigation methods in smear layer removal from the root canal walls using maleic acid (MA). Maxillary anterior teeth (N=30, n=10 per group) were decoronated, canals were enlarged with Protaper (size F4) and allocated to three groups: EndoUltra: 2.5 ml of 7% MA was irrigated for 30 s, followed by EndoUltra activation for 30 s; EndoSafe: EndoSafe irrigation system was used for 1 minute using 5 ml of 7% MA; Side-vented needle: 30 gauge needle irrigation was performed for 1 min using 5 ml of 7% MA. Read More

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http://dx.doi.org/10.1922/EJPRD_01817Husain06DOI Listing

[Assessment of prenatal care for indigenous women in Brazil: findings from the First National Survey of Indigenous People's Health and Nutrition].

Cad Saude Publica 2019 Aug 19;35Suppl 3(Suppl 3):e00181318. Epub 2019 Aug 19.

Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz, Rio de Janeiro, Brasil.

This study assesses prenatal care for indigenous women 14-49 years of age with children under five years of age in Brazil. The First National Survey of Indigenous People's Health and Nutrition assessed 3,967 women who met these criteria, of whom 41.3% in the North, 21. Read More

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http://dx.doi.org/10.1590/0102-311X00181318DOI Listing
August 2019
7 Reads

Effect of Er:YAG and Burs on Coronal Dentin Bond Strength Stability.

J Adhes Dent 2019 ;21(4):329-335

Purpose: To evaluate the immediate and aged bond strength and interfacial nanolaekage of different adhesives and protocols on dental elements prepared with diamond burs and Er:YAG laser.

Materials And Methods: Forty molar crowns were flattened and a standardized smear layer was created. Teeth were divided into two main groups according to the dentin cutting technique: 1. Read More

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http://dx.doi.org/10.3290/j.jad.a42932DOI Listing
October 2019
1 Read

Prevalence of Malaria and TB Coinfection at a National Tuberculosis Treatment Centre in Uganda.

J Trop Med 2019 25;2019:3741294. Epub 2019 Jul 25.

Makerere University College of Health Sciences, Department of Internal Medicine, P.O. Box 7272 Kampala, Uganda.

The prevalence of malaria and tuberculosis (TB) coinfection is not well established in countries that are highly burdened for both diseases. Malaria could impair TB containment and increase mortality of TB patients. The objective of this study was to determine the prevalence of malaria/TB coinfection among bacteriologically confirmed adult TB patients at a national TB treatment centre in Uganda. Read More

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http://dx.doi.org/10.1155/2019/3741294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683771PMC
July 2019
2 Reads

Analysis of drug resistance mutations in pulmonary Mycobacterium tuberculosis isolates in the Southern coastal region of Andhra Pradesh, India.

Braz J Infect Dis 2019 Sep - Oct;23(5):281-290. Epub 2019 Aug 14.

Vikrama Simhapuri University, Andhra Pradesh, India. Electronic address:

Purpose And Objectives: Detection of drug resistance plays a crucial role in tuberculosis (TB) treatment and prevention of Mycobacterium tuberculosis (MTB) transmission. The aim of this study was to determine the levels and patterns of resistance of MTB isolates to two key anti-TB drugs (rifampicin, RIF and isoniazid, INH) and the type of mutations in drug resistance genes (rpoB, katG and inhA) of the isolates at the southern coastal region of Andhra Pradesh, India, using commercially available GenoType MTBDRplus assay under the Revised National TB Control Program.

Methods: GenoType MTBDRplus assay was performed on 2859 sputum smear-positive samples and the mutations in the genes responsible for resistance (rpoB, katG and inhA) were analyzed. Read More

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http://dx.doi.org/10.1016/j.bjid.2019.07.002DOI Listing
December 2019
1 Read

Costs and operation management of community outreach program for tuberculosis in tribal populations in India.

Public Health Action 2019 Jun;9(2):58-62

Stop TB Partnership, Geneva, Switzerland.

Objective: To evaluate costs of an active case finding (ACF) program with tuberculosis (TB) treatment delivery and monitoring, which targeted a rural tribal population in India.

Method: A time and motion study was conducted to evaluate operations and workload. Costs from the program perspective were assessed using both the bottom-up and top-down costing methods, exclusive of routine TB care costs. Read More

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http://dx.doi.org/10.5588/pha.18.0091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645447PMC

Combined dynamic spectral imaging and routine colposcopy strategy for the diagnosis of pre-cancerous cervical lesions.

Authors:
Dan Liu Wanliang Hu

Exp Ther Med 2019 Sep 1;18(3):1521-1526. Epub 2019 Jul 1.

Department of Medicine, Jinggangshan University, Ji'an, Jiangxi 343009, P.R. China.

The present study aimed to investigate the sensitivity and specificity of combined dynamic spectral imaging (DySI) and routine colposcopy in diagnosing pre-cancerous lesions in subjects with abnormal cytological results. The retrospective study included 146 patients diagnosed with cervical lesions and atypical squamous cells of undetermined significance according to a colposcopy examination. Data from colposcopy clinics were used to evaluate performance of DySI in different histological types. Read More

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http://dx.doi.org/10.3892/etm.2019.7719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676200PMC
September 2019
4 Reads
0.941 Impact Factor

Development and evaluation of novel bio-safe filter paper-based kits for sputum microscopy and transport to directly detect Mycobacterium tuberculosis and associated drug resistance.

PLoS One 2019 13;14(8):e0220967. Epub 2019 Aug 13.

Center for Bio-design and Diagnostics, Translational Health Science and Technology Institute, NCR Biotech Science Cluster, 3rd Milestone, Faridabad-Gurgaon Expressway, Faridabad, India.

India has the highest burden of Tuberculosis (TB) and multidrug-resistant TB (MDR-TB) worldwide. Innovative technology is the need of the hour to identify these cases that remain either undiagnosed or inadequately diagnosed due to the unavailability of appropriate tools at primary healthcare settings. We developed and evaluated 3 kits, namely 'TB Detect' (containing BioFM-Filter device), 'TB Concentration and Transport' (containing Trans-Filter device) and 'TB DNA Extraction' kits. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0220967PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692035PMC
August 2019
5 Reads

Diagnostic excision of the cervix in women over 40 years with human papilloma virus persistency and normal cytology.

Eur J Obstet Gynecol Reprod Biol X 2019 Jul 8;3:100042. Epub 2019 May 8.

Department of Women's and Children's Health, Uppsala University, SE-751 85 Uppsala, Sweden.

Objective: Persistent infection with human papillomavirus (HPV) is recognized as the main risk factor of cervical cancer. Investigation via cytology and colposcopy have lower sensitivity than HPV testing in the diagnosis of high-grade cervical intraepithelial neoplasia (CIN2+). Despite normal cytology and colposcopy findings women with persistent HPV infection have an increased risk of CIN2+. Read More

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http://dx.doi.org/10.1016/j.eurox.2019.100042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687369PMC
July 2019
4 Reads

Serologic markers of previous malaria exposure and functional antibodies inhibiting parasite growth are associated with parasite kinetics following a Plasmodium falciparum controlled human infection.

Clin Infect Dis 2019 Aug 12. Epub 2019 Aug 12.

Disease Control and Elimination Theme, Medical Research Council Unit, The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia.

Background: We assessed the impact of exposure to P. falciparum on parasite kinetics, clinical symptoms, and functional immunity after controlled human malaria infection (CHMI) in two cohorts with different levels of previous malarial exposure.

Methods: Nine adult males with high (sero-high) and ten with low (sero-low) previous exposure received 3200 PfSPZ of PfSPZ Challenge by direct venous inoculation and were followed for 35 days for parasitemia by thick blood smear (TBS) and quantitative polymerase chain reaction (qPCR). Read More

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http://dx.doi.org/10.1093/cid/ciz740DOI Listing
August 2019
6 Reads

Diagnosis of tuberculosis through breath test: A systematic review.

EBioMedicine 2019 Aug 8;46:202-214. Epub 2019 Aug 8.

University of Groningen, University Medical Centre Groningen, Department of Pulmonary Diseases and Tuberculosis, Groningen, the Netherlands; University of Groningen, University Medical Center Groningen, Department of Internal Medicine-Infectious Diseases, Groningen, the Netherlands. Electronic address:

Background: Breath tests may diagnose tuberculosis (TB) through detecting specific volatile organic compounds produced by Mycobacterium tuberculosis or the infected host.

Methods: To estimate the diagnostic accuracy of breath test with electronic-nose and other devices against culture or other tests for TB, we screened multiple databases until January 6, 2019.

Findings: We included fourteen studies, with 1715 subjects in the analysis. Read More

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http://dx.doi.org/10.1016/j.ebiom.2019.07.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712009PMC
August 2019
7 Reads

Evaluation of debris and smear layer removal with XP-endo finisher: A scanning electron microscopic study.

Indian J Dent Res 2019 May-Jun;30(3):420-423

Department of Conservative Dentistry and Endodontics, Faculty of Dental Sciences, Sri Ramachandra University, Chennai, Tamil Nadu, India.

Context: The presence of smear layer and debris can prevent the irrigant and sealer from penetrating the dentinal tubules thereby compromising the seal of the root canal filling.

Aim: This study aims to evaluate the efficacy of XP-endo Finisher with ProTaper Next and HyFlex in smear layer and debris removal.

Materials And Methods: : Thirty-two extracted mandibular premolar teeth were selected and sectioned at the cementoenamel junction. Read More

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http://dx.doi.org/10.4103/ijdr.IJDR_655_17DOI Listing
October 2019
1 Read

A clinical evaluation on the effect of astringent on keratinization of oral mucosa before and after the insertion of complete denture.

Indian J Dent Res 2019 May-Jun;30(3):347-351

Department of Prosthodontics and Crown and Bridge, JSS Dental College and Hospital (Constituent College) Jagadguru Sri Shivarathreeswara University, JSS Medical Institutions Campus, Sri Shivarathreeswara Nagar, Mysuru, Karnataka, India.

Context: Conventional complete dentures still remain a viable method of treatment for many patients in this era of fixed prosthesis like dental implants. All patients undergoing complete denture treatment need nonsurgical preprosthetic treatment for the preparation of healthy denture bearing mucosa as well-keratinized healthy mucosa is desirable for a complete denture.

Aims: To evaluate and compare the keratinization before and after denture insertion at intervals of 1 week and 1 month. Read More

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http://dx.doi.org/10.4103/ijdr.IJDR_620_17DOI Listing
October 2019

Secondary cervical cancer prevention in routine prenatal care - coverage, results and lessons for the future.

Ginekol Pol 2019 ;90(7):396-402

2nd Chair and Department of Obstetrics and Gynecology, Medical University of Warsaw, Poland.

Objectives: Cervical cancer is the fourth most common type of cancer among women worldwide and one of the most common malignancies diagnosed in gravidas. Therefore, routine antenatal Pap smear is such an important examination. The aim of the study was to assess the prevalence of Pap smear performance during prenatal care and to determine possible factors affecting it. Read More

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http://dx.doi.org/10.5603/GP.2019.0068DOI Listing
January 2019
2 Reads

Diagnostic tools in late onset Pompe disease (LOPD).

Ann Transl Med 2019 Jul;7(13):286

Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.

Pompe disease is a rare metabolic disorder due to deficiency of the lysosomal acid alpha-glucosidase (GAA) that causes glycogen accumulation in all tissues with a predominant involvement of skeletal muscle. The late onset form of Pompe disease (LOPD) is characterized by a progressive weakness of proximal and axial muscles, often mimicking limb-girdle muscular dystrophies or inflammatory myopathies, with respiratory distress mainly due to a diaphragmatic weakness. Diagnostic delay is still common, and clinicians need a high index of suspicion to recognize this condition because the disorder is quite rare, the clinical spectrum is wide, and signs and symptoms are not distinguishable from those in other neuromuscular disorders that present in a similar fashion. Read More

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http://dx.doi.org/10.21037/atm.2019.06.60DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642940PMC
July 2019
5 Reads

National Control of Tuberculosis: Does Primary Health Care System Play a Crucial Role in the Fight Against Tuberculosis?

Turk Thorac J 2019 Jul 30;20(4):230-235. Epub 2019 Jul 30.

Family Physician, Provincial Health Directorate, Elazığ, Turkey.

Objectives: To analyze the tuberculosis control studies in a primary health care center and to observe the changes throughout the years.

Materials And Methods: Data of patients followed up between 2005 and 2014 in the Elazığ Dispensary were investigated retrospectively.

Results: Of the total 1,251 patients, 51. Read More

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http://dx.doi.org/10.5152/TurkThoracJ.2018.092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777651PMC
July 2019
2 Reads

Correlation between Allergic Rhinitis and Otitis Media with Effusion.

Iran J Otorhinolaryngol 2019 Jul;31(105):209-215

Cancer Molecular Pathology Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Introduction: Otitis media with effusion (OME) is prevalent among children in such a way that it is the most common cause of hearing loss and surgery in childhood. Immunoglobulin E (IgE) mediated hypersensitivity has been proposed as a causative factor in the development of OME; however, there has been contrasting data in this regard. Therefore, the present study aimed to detect the possibilities of interconnection. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6666939PMC
July 2019
6 Reads

Burden and genotype distribution of high-risk Human Papillomavirus infection and cervical cytology abnormalities at selected obstetrics and gynecology clinics of Addis Ababa, Ethiopia.

BMC Cancer 2019 Aug 5;19(1):768. Epub 2019 Aug 5.

Department of Medical Laboratory Sciences, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.

Background: Human papillomavirus is recognized as a major cause of cervical cancer. It is estimated that annually, 7,095 women are diagnosed with cervical cancer and 4,732 die from the disease in Ethiopia. Understanding that the screening practice is very poor and the coverage is very limited, this disease burden is one of the major public health agendas in Ethiopia. Read More

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http://dx.doi.org/10.1186/s12885-019-5953-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683490PMC
August 2019
1 Read

Effect of peracetic acid used as single irrigant on the smear layer, adhesion, and penetrability of AH Plus.

Braz Oral Res 2019 Jul 29;33:e057. Epub 2019 Jul 29.

Department of Restorative Dentistry, UNESP - São Paulo State University, School of Dentistry, Araraquara, SP, Brazil.

The aim of this study was to evaluate the effect of peracetic acid (PAA) as a single irrigant on the smear layer, on the intraradicular dentinal bond strength, and on the penetrability of an epoxy-based resin sealer into the dentinal tubules. A total of 120 roots were distributed into 4 groups according to the irrigant used in root canal preparation: 1% PAA (PAA); 2.5% NaOCl followed by final irrigation with 17% EDTA and 2. Read More

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http://dx.doi.org/10.1590/1807-3107bor-2019.vol33.0057DOI Listing
July 2019
2 Reads

A tuberculosis outbreak at an insecure, temporary housing facility, manga café, Tokyo, Japan, 2016-2017.

Epidemiol Infect 2019 Jan;147:e222

Research Institute of Tuberculosis,Tokyo,Japan.

In November 2016, a woman in her 30s who stayed at an insecure, temporary housing facility, a manga café in Tokyo, Japan, for a year was diagnosed with sputum smear-positive tuberculosis (TB). Since the café had 31 staff members and provided with accommodation to many people, the local health office initiated a contact investigation. This study aims to characterise the cases found in the outbreak. Read More

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http://dx.doi.org/10.1017/S0950268819001092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625208PMC
January 2019
1 Read

Cryotherapy as a Method for Relieving Symptoms of Cervical Ectopy: A Randomized Clinical Trial.

Oman Med J 2019 Jul;34(4):322-326

Modeling in Health Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran.

Objectives: Benign cervical ectopy (CE) may cause chronic or recurrent symptoms leading to women repeatedly being referred to gynecology clinics. We aimed to present a safe and effective method for relieving symptoms of CE.

Methods: This double-blind clinical trial was conducted among 164 women with CE who complained of persistent or recurrent symptoms of cervicitis in the last six months. Read More

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http://dx.doi.org/10.5001/omj.2019.63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642705PMC
July 2019
13 Reads

The Utility of CSF Xpert MTB/RIF in Diagnosis of Tubercular Meningitis in Children.

Indian J Pediatr 2019 12 19;86(12):1089-1093. Epub 2019 Jul 19.

Department of Pediatrics, Karnataka Institute of Medical Sciences, Hubli, Karnataka, 580021, India.

Objective: To determine the utility of CSF Xpert MTB/RIF (GeneXpert) in diagnosis of tubercular meningitis in children in the age group of 2 mo to 12 y.

Methods: This hospital based prospective observational study was conducted at Department of Pediatrics, Karnataka Institute of Medical Sciences (KIMS), Hubli from December 2015 through November 2016. All children with clinically suspected tuberculous meningitis (TBM) were included in the study. Read More

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http://dx.doi.org/10.1007/s12098-019-03032-0DOI Listing
December 2019
2 Reads

Intensified tuberculosis and HIV surveillance in a prison in Northeast India: Implementation research.

PLoS One 2019 29;14(7):e0219988. Epub 2019 Jul 29.

Department of Health and Family Welfare, Mizoram, Aizawl, India.

Structural and individual level factors in prisons create challenges towards detection and management of HIV/tuberculosis. WHO and India's HIV/tuberculosis control programs recommend intensified case finding in prisons. Low HIV and tuberculosis detection rates suggest poor implementation of existing surveillance strategies within the prison healthcare system in Mizoram's capital city of Aizawl. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0219988PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662996PMC
July 2019
1 Read

A Comparison of Cytomorphological Features of ASC-H Cells Based on Histopathological Results Obtained from a Colposcopic Target Biopsy Immediately after Pap smear Sampling.

Asian Pac J Cancer Prev 2019 07 1;20(7):2139-2143. Epub 2019 Jul 1.

Department of Medical Technology, Faculty of Health Sciences, Kyorin University, 5-4-1 Shimorenjaku, Mitaka-shi, 181-8621, Tokyo, Japan. Email:

Background: To compare the cytomorphological features of atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion (ASC-H) observed in a liquid-based Pap smear with the histopathological features observed in a concurrent colposcopic biopsy specimen obtained immediately after obtaining the Pap smear. Methods: Cytomorphological features such as cytoplasmic differentiation, nuclear/cytoplasm (N/C) ratio, chromatin pattern, thickening of nuclear contour, and the appearance of the nucleolus of 247 ASC-H obtained from 25 liquid-based Pap smear ASC-H cases were compared with those of the cells obtained from biopsied samples. Human papillomavirus (HPV) infection was tested for 39 HPV genotypes using Uniplex E6/E7 polymerase chain reaction method. Read More

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http://dx.doi.org/10.31557/APJCP.2019.20.7.2139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745206PMC
July 2019
1 Read

Human Papillomavirus Genotyping among Different Cervical Smears in Duhok/Iraq.

Asian Pac J Cancer Prev 2019 07 1;20(7):2059-2064. Epub 2019 Jul 1.

Department of Microbiology, College of Medicine, University of Duhok, Iraq. Email:

Background/Objective: Cervical cancer ranks the second among the most common gynecologic cancers. This study was established to determine the distribution of cervical HPV genotypes among different Pap readings in Duhok/Iraq. Methods: Between January and September-2016, HPV-DNA was tested in 64 women. Read More

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http://dx.doi.org/10.31557/APJCP.2019.20.7.2059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745234PMC

Occlusion of the central retinal artery in malaria.

BMJ Case Rep 2019 Jul 26;12(7). Epub 2019 Jul 26.

Vitreo-Retina and Uveitis Services, LV Prasad Eye Institute, Visakhapatnam, Andhra Pradesh, India.

A 40-year-old woman presented with sudden painless diminution of vision in left eye. The best corrected visual acuity was 20/20 in the right eye and 20/400 in the left eye. The vision loss occurred 3 days after the onset of fever with chills and rigour. Read More

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http://dx.doi.org/10.1136/bcr-2019-230137DOI Listing
July 2019
6 Reads

Comparable expression of miR-let-7b, miR-21, miR-182, miR-145, and p53 in serum and cervical cells: Diagnostic implications for early detection of cervical lesions.

Int J Health Sci (Qassim) 2019 Jul-Aug;13(4):29-38

Department of Family Medicine, State Hospital Ijaiye, Abeokuta, Ogun State, Nigeria.

Objective: The high mortality associated with cervical cancer is due to low uptake of Pap smear test, lack of early diagnostic biomarkers and less-invasive approach, and late presentation of the disease. This study evaluated the expression of hsa-miR-let-7b, hsa-miR-21, hsa-miR-125b, hsa-miR-143, hsa-miR-145, hsa-miR-146a, hsa-miR-155, hsa-miR-182, hsa-miR-200c, and p53 in serum and cervix in relation to classes of Pap smear, in a bid to identify a serum panel for early diagnosis of cervical lesions.

Methodology: This study included 329 women; 159 healthy women (HW), 46 cervicitis, 46 atypical squamous cells of undetermined significance (ASCUS), 40 low-grade squamous cell intraepithelial lesion (LSIL), 28 high-grade squamous cell intraepithelial lesion (HSIL), and 10 squamous cell carcinoma (SCC). Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619463PMC
July 2019
3 Reads

The influence of probiotics on genital high-risk human papilloma virus clearance and quality of cervical smear: a randomized placebo-controlled trial.

BMC Womens Health 2019 07 24;19(1):103. Epub 2019 Jul 24.

Department of Obstetrics and Gynecology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, 123, Ta Pei Road, Niao Sung District, Kaohsiung City, 83301, Taiwan, Republic of China.

Background: Probiotics has been shown to be effective in reducing vaginal colonization of pathogenic organisms. The aim of this study was to investigate the influence of probiotic strains Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 on genital high-risk human papilloma virus (HR-HPV) clearance and quality of cervical smear.

Methods: This was a randomized, double-blinded, placebo-controlled trial. Read More

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http://dx.doi.org/10.1186/s12905-019-0798-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657108PMC
July 2019
4 Reads

Comorbidity of intestinal helminthiases among malaria outpatients of Wondo Genet health centers, southern Ethiopia: implications for integrated control.

BMC Infect Dis 2019 Jul 24;19(1):659. Epub 2019 Jul 24.

Department of Microbial, Cellular and Molecular Biology, College of Natural Sciences, Addis Ababa University, P. O. Box, 1176, Addis Ababa, Ethiopia.

Background: It is estimated that over a third of the world population is infected by malaria and helminthiases mainly among communities with high poverty indices. The distribution of these parasitic infections overlaps in many epidemiological settings and have varying outcomes in the host. In this paper we report the prevalence of malaria and intestinal helminthiases coinfections among malaria suspected patients and the association of helminthiases with the occurrence of malaria and its outcomes in Wondo Genet, southern Ethiopia. Read More

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http://dx.doi.org/10.1186/s12879-019-4290-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657167PMC
July 2019
2 Reads
2.613 Impact Factor

Reactional changes in short-term levonorgestrel-releasing intrauterine system (lng-ius) use.

Rev Assoc Med Bras (1992) 2019 Jul 22;65(6):857-863. Epub 2019 Jul 22.

Department of Gynecology and Obstetrics, University of Campinas - UNICAMP, Campinas, São Paulo, Brasil.

Objective: To evaluate endocervical and vaginal environment changes in women using a levonorgestrel-releasing intrauterine system (LNG-IUS).

Methods: A quasi-experimental study included sixty women who had an LNG-IUS inserted in the Family Planning Clinic of UNICAMP between April and November of 2016. Women in reproductive age, non-pregnant, without the use of antibiotics and contraceptives seeking for LNG-IUS insertion were selected for this study. Read More

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http://dx.doi.org/10.1590/1806-9282.65.6.857DOI Listing
July 2019
3 Reads

Empiric treatment of pulmonary TB in the Xpert era: Correspondence of sputum culture, Xpert MTB/RIF, and clinical diagnoses.

PLoS One 2019 24;14(7):e0220251. Epub 2019 Jul 24.

Uganda Tuberculosis Implementation Research Consortium, Makerere University, Kampala, Uganda.

Background: Clinical tuberculosis diagnosis and empiric treatment have traditionally been common among patients with negative bacteriologic test results. Increasing availability of rapid molecular diagnostic tests, including Xpert MTB/RIF and the new Xpert Ultra cartridge, may alter the role of empiric treatment.

Methods: We prospectively enrolled outpatients age > = 15 who were evaluated for pulmonary tuberculosis at three health facilities in Kampala, Uganda. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0220251PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6655770PMC
July 2019
4 Reads
3.234 Impact Factor

Diagnostic accuracy of droplet digital PCR analysis of cerebrospinal fluid for tuberculous meningitis in adult patients.

Clin Microbiol Infect 2020 Feb 20;26(2):213-219. Epub 2019 Jul 20.

Beijing Key Laboratory for Drug Resistant Tuberculosis Research, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, China. Electronic address:

Objectives: Tuberculous meningitis (TBM) is difficult to diagnose. Digital PCR (dPCR) is a novel method which can quantify trace nucleic acids. This study sought to evaluate the diagnostic accuracy of dPCR analysis of cerebrospinal fluid (CSF) for TBM. Read More

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http://dx.doi.org/10.1016/j.cmi.2019.07.015DOI Listing
February 2020
6 Reads

[Use of HPV virologic test for atypical glandular cells in Alsace between 2014 and 2016].

Gynecol Obstet Fertil Senol 2019 11 20;47(11):802-807. Epub 2019 Jul 20.

Service de gynécologie, pôle de gynécologie-obstétrique, CHRU de Strasbourg, 5, avenue Molière, 67200 Strasbourg cedex, France.

Objectives: The new recommendations by the National Institute of Cancer (January 2017) recommend the use of a complementary human papillomavirus (HPV) virologic test during the diagnosis of atypical glandular cells in pap smear. The aim of this study was the performance analysis of the HPV virologic test for the detection of significant histological cervical abnormalities (CIN2 or more) in case of atypical glandular cells before the new recommendations were published.

Methods: We performed a descriptive and retrospective cohort study in Alsace between January 2014 and December 2016. Read More

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http://dx.doi.org/10.1016/j.gofs.2019.07.005DOI Listing
November 2019

Prevalence rate of undiagnosed tuberculosis in the community in Ethiopia from 2001 to 2014: systematic review and meta-analysis.

Arch Public Health 2019 11;77:33. Epub 2019 Jul 11.

College of health science, Debere Markos University, Debere Markos, Ethiopia.

Background: In Ethiopia individual report indicated nearly 30% of incident cases of tuberculosis remained undiagnosed. Therefore, this systematic review and meta-analysis was aimed to determine the pooled prevalence rate of undiagnosed smear positive pulmonary tuberculosis (PTB) using community based studies published in Ethiopia.

Methods: MEDLINE/PubMed, 'Cochrane' library, and Google scholar databases were searched, and reference list of studies on tuberculosis in Ethiopia were reviewed. Read More

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http://dx.doi.org/10.1186/s13690-019-0360-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6622003PMC

Isolated Bilateral Pinna Swelling: A Rare Initial Presentation of Leprosy.

Open Access Maced J Med Sci 2019 Jun 15;7(11):1815-1817. Epub 2019 Jun 15.

Primary Care Medicine Discipline, Faculty of Medicine, Universiti Teknologi MARA, 47000 Sungai Buloh, Selangor, Malaysia.

Background: Leprosy or Hansen disease is a chronic infectious disease that causes social stigma due to its deforming bodily appearance and physical disability. It has a wide spectrum of presentation affecting diagnosis.

Case Report: A 21-year-old man who presented with chronic isolated bilateral pinna swelling as a result of leprosy is reported. Read More

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http://dx.doi.org/10.3889/oamjms.2019.481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614257PMC
June 2019
3 Reads

Cobas 4800 HPV detection in cervical samples of Polish women.

Contemp Oncol (Pozn) 2019 13;23(2):92-95. Epub 2019 Jun 13.

Department of Obstetrics and Gynaecology and Gynaecological Oncology, Regional Hospital in Kalisz, Poland.

Introduction: Long-term infection with human papillomavirus (HPV) is the cause of cervical cancer and its precursor - cervical intraepithelial neoplasia (CIN). The presence of HPV infection can be presumed in more than 99% of cases of cervical cancer worldwide. The introduction of DNA testing for the presence of HPV has increased the effectiveness of screening programs for the detection of this cancer. Read More

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http://dx.doi.org/10.5114/wo.2019.85880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630389PMC
June 2019
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Prevalence of pulmonary tuberculosis in Tibet Autonomous Region, China, 2014.

Int J Tuberc Lung Dis 2019 06;23(6):735-740

Shandong Center for Disease Control and Prevention, Academy of Preventive Medicine, Shandong University, Jinan, China.

SETTING Tibet Autonomous Region, China. OBJECTIVES To determine the prevalence of pulmonary tuberculosis (TB) in Tibet. DESIGN We conducted a population-based, cross-sectional survey among residents aged ≥15 years in Tibet, China, in 2014. Read More

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http://dx.doi.org/10.5588/ijtld.18.0614DOI Listing

A randomised controlled trial of stepwise sputum collection to increase yields of confirmed tuberculosis.

Int J Tuberc Lung Dis 2019 06;23(6):685-691

Shenzhen Center for Chronic Disease Control, Shenzhen, Key Laboratory of Medical Molecular Virology, School of Basic Medical Sciences and Shanghai Public Health Clinical Center, Fudan University, Shanghai.

SETTING The proportion of bacteriologically confirmed tuberculosis (TB) in China has decreased far below the worldwide average. OBJECTIVE To investigate whether stepwise measures to ensure sputum quality can improve the rate of bacteriologically confirmed TB. DESIGN We enrolled 980 adults with suspected TB from three counties in China during 2017 for this multicentre randomised controlled trial. Read More

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http://dx.doi.org/10.5588/ijtld.18.0524DOI Listing

Risk factors and relationship between screening periodicity and risk of cervical cancer among nurses and midwives. A cross-sectional study.

Sao Paulo Med J 2019 Jul 15;137(2):119-125. Epub 2019 Jul 15.

MD. Professor, Department of Public Health, Faculty of Medicine, Dokuz Eylül University Izmir, Turkey.

Background: If nurses and midwives undergo cervical cancer screening regularly, they can become role models for other women regarding this screening.

Objectives: The aims here were (i) to determine factors associated with undergoing cervical cancer screening; and (ii) to examine the association of cervical cancer screening periodicity with cervical cancer risk levels among nurses and midwives.

Design And Setting: Cross-sectional study in a public hospital. Read More

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http://dx.doi.org/10.1590/1516-3180.2018.0244230119DOI Listing

Barriers to Pap Smear Among Homeless Women at Albuquerque Healthcare for the Homeless.

J Community Health 2019 Dec;44(6):1185-1192

College of Population Health, 1 University of New Mexico, MSC09 5070, Albuquerque, NM, 87131-0001, USA.

The purpose of this cross-sectional survey study was to explore common barriers to adequate Pap smear utilization among homeless women, and the factors that may relate to cervical cancer testing in this population. Participants consisted of adult women recruited at a healthcare facility for the homeless. Data were collected through a self-completed questionnaire on knowledge, attitudes and intentions about Pap smears and cervical cancer. Read More

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http://dx.doi.org/10.1007/s10900-019-00704-yDOI Listing
December 2019

Quick Leukocyte Nucleus Segmentation in Leukocyte Counting.

Comput Math Methods Med 2019 11;2019:3072498. Epub 2019 Jun 11.

College of Electronic Information Engineering, Sichuan University, Chengdu, Sichuan 610064, China.

The leukocyte nucleus quick segmentation is one of the key techniques in leukocyte real-time online scanning of human blood smear. We propose a quick leukocyte nucleus segmentation method based on the component difference in RGB color space. By analyzing the captured microscopic images of the peripheral blood smears from the autoscanning microscope, it is found that the difference values between B component and G component (B - G values) in the regions of the leukocyte nuclei and the platelets are much bigger than those in the other regions, even in the regions including the stains. Read More

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http://dx.doi.org/10.1155/2019/3072498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594331PMC

Assessing competence for helminthiases: A lesson learnt from national contest of parasitic diseases in China in 2012-2016.

Acta Trop 2019 Oct 9;198:105078. Epub 2019 Jul 9.

National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory of Parasite and Vector Biology, Ministry of Health, WHO Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai, 20025, China. Electronic address:

This study aimed to assess the competency of health professionals on helminthiasis control in China. The assessment system comprised of two parts, one being the parasitological knowledge test and the other a technical skills assessment. The knowledge test mainly examined morphology, epidemiology, life history and diagnosis of common and important parasites. Read More

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http://dx.doi.org/10.1016/j.actatropica.2019.105078DOI Listing
October 2019
7 Reads

Effect of silver diamine fluoride and potassium iodide on bonding to demineralized dentin.

Am J Dent 2019 Jun;32(3):143-146

Department of Restorative Dentistry, University of Washington School of Dentistry, Seattle, WA, USA,

Purpose: To evaluate the microtensile bond strength (MTBS) of resin composite to demineralized dentin treated with SDF or SDF-KI.

Methods: Occlusal enamel of 30 caries-free extracted human molars was removed to expose flat dentin surfaces. Specimens were immersed in demineralizing solution (pH 4. Read More

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June 2019
3 Reads