Psychosom Med 2022 06 14;84(5):621-631. Epub 2022 Apr 14.
From the Department of Psychiatry (H.-J. Tsai, S.-J. Tsai), Taipei Veterans General Hospital; Institute of Brain Science (H.-J. Tsai, A.C. Yang, S.-J. Tsai, Kuo, C.C.H. Yang), National Yang Ming Chiao Tung University, Digital Medicine Center (A.C. Yang), National Yang Ming Chiao Tung University; Department of Medical Research (A.C. Yang), Taipei Veterans General Hospital, Taipei, Taiwan; Osher Center for Integrative Medicine (Ma), Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School; Center for Dynamical Biomarkers (Ma, Peng), Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, Massachusetts; Clinical Research Center (Kuo), Taoyuan Psychiatric Center, Ministry of Health and Welfare, Taoyuan; and Sleep Research Center (H.-J. Tsai, Kuo, C.C.H. Yang), National Yang Ming Chiao Tung University, Taipei, Taiwan.
Objective: Autonomic neural controls in sleep regulation have been previously demonstrated; however, whether these alternations can be observed by different sleep staging approaches remains unclear. Two established methods for sleep staging-the standardized visual scoring and the cardiopulmonary coupling (CPC) analysis based on electrocardiogram-were used to explore the cardiovascular profiles of sleep.
Methods: Overnight polysomnography was recorded together with continuous beat-to-beat blood pressure. Read More