3,252 results match your criteria Sleep Dysfunction in Women


Global epidemiology of gout: prevalence, incidence, treatment patterns and risk factors.

Nat Rev Rheumatol 2020 Jul 15;16(7):380-390. Epub 2020 Jun 15.

Primary Care Centre Versus Arthritis, School of Primary, Community and Social Care, Keele University, Keele, UK.

Gout is the most common inflammatory arthritis and occurs when hyperuricaemia, sustained elevation of serum urate levels resulting in supersaturation of body tissues with urate, leads to the formation and deposition of monosodium urate crystals in and around the joints. Recent reports of the prevalence and incidence of gout vary widely according to the population studied and methods employed but range from a prevalence of <1% to 6.8% and an incidence of 0. Read More

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http://dx.doi.org/10.1038/s41584-020-0441-1DOI Listing

Response to: migraine symptoms and the role of the autonomic dysfunction.

Eur J Neurol 2020 Jun 4. Epub 2020 Jun 4.

Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1111/ene.14374DOI Listing

The Neuropsychological Profile of Attention Deficits of Patients with Obstructive Sleep Apnea: An Update on the Daytime Attentional Impairment.

Brain Sci 2020 May 27;10(6). Epub 2020 May 27.

"V. Fazzi" Hospital, ENT, ASL, 73100 Lecce, Italy.

Introduction: Patients with obstructive sleep apnea (OSA) suffer from several neurocognitive disturbances. One of the neuropsychological processes most investigated in OSA patients is attention, but the results have been controversial. Here, we update the attention profile of OSA patients with the final aim to improve attention assessment, with a possible impact on clinical and medical-legal practices, in terms of which attention subdomains and parameters need consideration and which one is a high-risk OSA phenotype for attention dysfunctions. Read More

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http://dx.doi.org/10.3390/brainsci10060325DOI Listing

Evaluation of the masticatory biomechanical function in Down syndrome and its Influence on sleep disorders, body adiposity and salivary parameters.

J Oral Rehabil 2020 May 28. Epub 2020 May 28.

Center of Biosciences Applied to Patients with Special Health Care Needs (CEBAPE) and Multiprofessional Service of Oral Medicine for People with Disability and Caregivers (SEMMO) of the Institute of Science and Technology, São José dos Campos Campus, São Paulo State University-UNESP, São Paulo, Brazil.

Objective: To evaluate the phenotypic features of the masticatory biomechanics in atypical subjects with Down syndrome (DS). Its influence was analysed on sleep disorders, body adiposity and its risks, and some physicochemical properties of saliva.

Methods: Seventy subjects were enrolled to assess masticatory biomechanical function and divided into two groups: DS and control groups. Read More

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http://dx.doi.org/10.1111/joor.13023DOI Listing

N8-Acetylspermidine: A Polyamine Biomarker in Ischemic Cardiomyopathy With Reduced Ejection Fraction.

J Am Heart Assoc 2020 Jun 27;9(11):e016055. Epub 2020 May 27.

Emory Clinical Cardiovascular Research Institute Division of Cardiology Department of Medicine Emory University School of Medicine Atlanta GA.

Background Patients with ischemic cardiomyopathy (ICM) have worse outcomes than those with coronary artery disease alone and those with non-ICM. N8-acetylspermidine (N8AS) is a polyamine that regulates ischemic cardiac apoptosis and resultant cardiac dysfunction. We hypothesized that N8AS is a mechanistic biomarker of adverse outcomes in patients with ICM. Read More

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http://dx.doi.org/10.1161/JAHA.120.016055DOI Listing
June 2020
2.882 Impact Factor

Dietary Approaches to Stop Hypertension (DASH) Score and Its Association with Sleep Quality in a National Survey of Middle-Aged and Older Men and Women.

Nutrients 2020 May 22;12(5). Epub 2020 May 22.

Health Disparities Research Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, NIA/NIH/IRP, Baltimore, MD 21224, USA.

Complex processes appear to link sleep duration and quality with dietary patterns. Numerous studies show healthful benefits of the Dietary Approaches to Stop Hypertension (DASH) diet, but few have examined its association with sleep duration or quality. The current study tested cross-sectional associations of DASH diet quality score with sleep quality among adults. Read More

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http://dx.doi.org/10.3390/nu12051510DOI Listing

Association Between Sleep Disordered Breathing and Left Ventricular Function: A Cross-Sectional Analysis of the ECHO-SOL Ancillary Study.

Circ Cardiovasc Imaging 2020 May 15;13(5):e009074. Epub 2020 May 15.

Departments of Medicine and Epidemiology & Population Health, Albert Einstein College of Medicine (C.J.R.).

Background: Prior studies have found that sleep-disordered breathing (SDB) is common among those with left ventricular (LV) dysfunction and heart failure. Few epidemiological studies have examined this association, especially in US Hispanic/Latinos, who may be at elevated risk of SDB and heart failure.

Methods: We examined associations between SDB and LV diastolic and systolic function using data from 1506 adults aged 18 to 64 years in the Hispanic Community Health Study/Study of Latinos ECHO-SOL Ancillary Study (2011-2014). Read More

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http://dx.doi.org/10.1161/CIRCIMAGING.119.009074DOI Listing

Telehealth Home Support During COVID-19 Confinement for Community-Dwelling Older Adults With Mild Cognitive Impairment or Mild Dementia: Survey Study.

J Med Internet Res 2020 05 22;22(5):e19434. Epub 2020 May 22.

Department of Mental Health, Regional University Hospital of Málaga, Biomedical Research Institute of Malaga (IBIMA), Málaga, Spain.

Background: The public health emergency of coronavirus disease (COVID-19) is rapidly evolving worldwide; some countries, including Spain, have implemented restrictive measures. Populations that are vulnerable to this outbreak and its physical and mental health effects include community-dwelling older adults with mild cognitive impairment or mild dementia. Telehealth is a potential tool to deliver health care and decrease exposure risk. Read More

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http://dx.doi.org/10.2196/19434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247465PMC

Oxidative Stress Is Associated With Diastolic Dysfunction in Women With Ischemia With No Obstructive Coronary Artery Disease.

J Am Heart Assoc 2020 May 7;9(10):e015602. Epub 2020 May 7.

Barbra Streisand Women's Heart Center Cedars-Sinai Smidt Heart Institute Los Angeles CA.

Background Women with signs and symptoms of ischemia and no obstructive coronary artery disease often have evidence of diastolic dysfunction. Oxidative stress (OS) is associated with cardiovascular risk factors and adverse outcomes. The relationship between systemic OS and diastolic dysfunction is unknown. Read More

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http://dx.doi.org/10.1161/JAHA.119.015602DOI Listing

Influential factors on sexual function in infertile women with endometriosis: a path analysis.

BMC Womens Health 2020 May 5;20(1):92. Epub 2020 May 5.

Department of Biostatistics, Faculty of Medical Sciences, Shahid Beheshti University, Tehran, Iran.

Background: Endometriosis have a negative influence on women's sexual life. The aim of the current study was to test a conceptual model considering the interrelated role of anxiety, depression, sleep quality, physical activity, BMI, stage of endometriosis, the intensity of dyspareunia and pelvic pain on sexual function (SF) in infertile women with endometriosis. Also test the mediating role of sleep quality, anxiety, and depression. Read More

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http://dx.doi.org/10.1186/s12905-020-00941-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201757PMC

Feto-placental Dopplers are not altered in women with obstructive sleep apnoea symptoms.

Aust N Z J Obstet Gynaecol 2020 May 5. Epub 2020 May 5.

Mater Research Institute, University of Queensland, Brisbane, Queensland, Australia.

Background: Snoring, gasping or choking during sleep are common symptoms of sleep-disordered breathing and are associated with multiple adverse maternal and obstetric outcomes. The mechanisms responsible remain unknown; however, placental dysfunction is suspected.

Aims: The aim of this study was to investigate feto-placental and fetal cardiac function in women with pregnancies complicated by obstructive sleep apnoea symptoms. Read More

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http://dx.doi.org/10.1111/ajo.13166DOI Listing

Association between work productivity and sleep health: A cross-sectional study in Japan.

Sleep Health 2020 Apr 28. Epub 2020 Apr 28.

Department of Psychiatry, Tokyo Medical University, Tokyo, Japan; Department of Sleep and Psychiatry, Kanno Hospital, Saitama, Japan. Electronic address:

Objectives: To examine the impact of sleep health on work in Japan and to investigate the relationship between presenteeism and sleep health.

Design: Cross sectional analysis of a questionnaire survey.

Setting: Seventeen offices in Tokyo, Japan. Read More

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http://dx.doi.org/10.1016/j.sleh.2020.02.016DOI Listing

Cold extremities in migraine: a marker for vascular dysfunction in women.

Eur J Neurol 2020 Jul 20;27(7):1197-1200. Epub 2020 May 20.

Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.

Background And Purpose: Migraine is recognized as a vascular risk factor, especially in women. Presumably, migraine, stroke and cardiovascular events share pathophysiological mechanisms. Self-reported cold extremities were investigated as a marker for vascular dysfunction in migraine. Read More

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http://dx.doi.org/10.1111/ene.14289DOI Listing

Characterization of lung-to-finger circulation time in sleep study assessment: the Multi-Ethnic Study of Atherosclerosis.

Physiol Meas 2020 Jun 30;41(6):065004. Epub 2020 Jun 30.

Department of Medicine, University of Washington, Seattle, WA, United States of America.

Objectives: Lung-to-finger circulation time (LFCT) measured from sleep studies may reflect underlying cardiac dysfunction. We aimed to examine the distribution of LFCT in community-dwelling men and women in order to better understand the factors determining LFCT between and within subjects.

Approach: We included participants of the Multi-Ethnic Study of Atherosclerosis (MESA) Sleep with polysomnography-based evidence of sleep apnea (defined by apnea hypopnea index >15 hr). Read More

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http://dx.doi.org/10.1088/1361-6579/ab8e12DOI Listing

Sleep-disordered breathing does not impact maternal outcomes in women with hypertensive disorders of pregnancy.

PLoS One 2020 27;15(4):e0232287. Epub 2020 Apr 27.

Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia.

Objective: Sleep-disordered breathing (SDB) is characterised by intermittent hypoxemia, sympathetic activation and widespread endothelial dysfunction, sharing pathophysiologic features with the hypertensive disorders of pregnancy. We sought to determine whether coexisting SDB would adversely impact the outcomes of women with gestational hypertension (GH) and preeclampsia (PE), and healthy matched controls.

Study Design: Women diagnosed with GH or PE along with BMI- and gestation-matched normotensive controls underwent polysomnography in late pregnancy to establish the presence or absence of SDB (RDI ≥ 5). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0232287PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185691PMC

Sleep disorders and vascular responsiveness in patients with rheumatoid arthritis.

J Intern Med 2020 Apr 24. Epub 2020 Apr 24.

From the, Department of Medicine, the Rheumatology Unit, Azrieli Faculty of Medicine, Baruch Padeh Medical Center, Lower Galilee, Israel.

Background: Rheumatoid arthritis (RA) is the most common systemic autoimmune disease characterized by chronic systemic inflammation. Half of the deaths of patients with RA are due to cardiovascular diseases (CVD), considered to be 1.5 to -2. Read More

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http://dx.doi.org/10.1111/joim.13087DOI Listing

U-Shaped Association between Sleep Duration, C-Reactive Protein, and Uric Acid in Korean Women.

Int J Environ Res Public Health 2020 Apr 13;17(8). Epub 2020 Apr 13.

Department of Family Medicine, Yonsei University College of Medicine, 50-1, Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea.

Serum high-sensitivity C-reactive protein (hsCRP) and serum uric acid (SUA) are biomarkers that predict chronic inflammation and cardiovascular dysfunction. Therefore, we aimed to investigate the association between sleep duration, hsCRP, and SUA in Korean women. Cross-sectional data from the Seventh Korea National Health and Nutrition Examination Survey was analyzed. Read More

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http://dx.doi.org/10.3390/ijerph17082657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216061PMC

Treatment-induced symptoms, depression and age as predictors of sexual problems in premenopausal women with early breast cancer receiving adjuvant endocrine therapy.

Breast Cancer Res Treat 2020 Jun 9;181(2):347-359. Epub 2020 Apr 9.

International Breast Cancer Study Group (IBCSG) Coordinating Center, Effingerstrasse 40, 3008, Bern, Switzerland.

Purpose: Sexual dysfunction is an important concern of premenopausal women with early breast cancer. We investigated predictors of sexual problems in two randomized controlled trials.

Methods: A subset of patients enrolled in TEXT and SOFT completed global and symptom-specific quality-of-life indicators, CES-Depression and MOS-Sexual Problems measures at baseline, six, 12 and 24 months. Read More

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http://dx.doi.org/10.1007/s10549-020-05622-5DOI Listing
June 2020
3.940 Impact Factor

Prevalence, subtypes, and correlates of nocturia in the symptoms of Lower Urinary Tract Dysfunction Research Network cohort.

Neurourol Urodyn 2020 04 6;39(4):1098-1107. Epub 2020 Apr 6.

Department of Urology, University of Michigan, Ann Arbor, Michigan.

Aims: We determined the prevalence, severity, and correlates of nocturia in a large clinical cohort of patients.

Methods: Patients presenting with lower urinary tract symptoms (LUTS) completed 3-day bladder diaries. Nocturia was quantified based on the mean number of nighttime voids documented over the 3 days. Read More

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http://dx.doi.org/10.1002/nau.24338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238757PMC

Maternal sleep disordered breathing assessed by Epworth Sleepiness Scale and abnormal feto-placental Dopplers.

J Matern Fetal Neonatal Med 2020 Mar 23:1-7. Epub 2020 Mar 23.

Mater Research Institute, University of Queensland, South Brisbane, Australia.

Excessive daytime sleepiness is a frequently described phenomenon in pregnant women. The Epworth Sleepiness Scale (ESS) is a self reported standardized method of assessing sleep propensity and has been used extensively within pregnant populations. An elevated score is associated with sleep disordered breathing, as well as adverse obstetric and neonatal outcomes which may be indicative of a degree of placental dysfunction. Read More

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http://dx.doi.org/10.1080/14767058.2020.1743663DOI Listing

Association of Sleep-Disordered Breathing With Alzheimer Disease Biomarkers in Community-Dwelling Older Adults: A Secondary Analysis of a Randomized Clinical Trial.

JAMA Neurol 2020 Mar 23. Epub 2020 Mar 23.

Normandie Université, Université de Caen, Paris Sciences & Lettres Université, École Pratique des Hautes Études, Institut National de la Santé et de la Recherche Médicale, Unité 1077 "Neuropsychologie et Imagerie de la Mémoire Humaine," Centre Hospitalier Universitaire de Caen, GIP Cyceron, Caen, France.

Importance: Increasing evidence suggests that sleep-disordered breathing (SDB) increases the risk of developing Alzheimer clinical syndrome. However, the brain mechanisms underlying the link between SDB and Alzheimer disease are still unclear.

Objective: To determine which brain changes are associated with the presence of SDB in older individuals who are cognitively unimpaired, including changes in amyloid deposition, gray matter volume, perfusion, and glucose metabolism. Read More

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http://dx.doi.org/10.1001/jamaneurol.2020.0311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091393PMC

Evening and night exposure to screens of media devices and its association with subjectively perceived sleep: Should "light hygiene" be given more attention?

Sleep Health 2020 Mar 17. Epub 2020 Mar 17.

National Institute of Mental Health, Klecany, Czech Republic; Third Faculty of Medicine, Charles University, Prague, Czech Republic.

Objective: The aim of the study was to examine subjective sleep quality in a population of healthy volunteers and its association with evening and night light exposure to screens of media devices.

Methods: A total of 693 participants (mean age 31.2±11. Read More

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http://dx.doi.org/10.1016/j.sleh.2019.11.007DOI Listing

Sex-specific association of poor sleep quality with gray matter volume.

Sleep 2020 Mar 6. Epub 2020 Mar 6.

Institute of Diagnostic Radiology and Neuroradiology, Functional Imaging Unit, University, Medicine Greifswald, Greifswald, Germany.

Study Objectives: Previous studies were inconsistent with regard to the association of sleep dysfunction on the brain's gray matter volume (GMV). The current study set out to investigate if there is a moderating effect of sex on the relationship between sleep quality in healthy individuals and GMV.

Methods: We applied voxel-based morphometry in 1074 young adults of the "Human Connectome Project". Read More

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http://dx.doi.org/10.1093/sleep/zsaa035DOI Listing

Sleep duration is associated with vitamin D deficiency in older women living in Macao, China: A pilot cross-sectional study.

PLoS One 2020 4;15(3):e0229642. Epub 2020 Mar 4.

Department of Physiology, School of Medical Sciences, Bosch Institute, The University of Sydney, Sydney, Australia.

Chinese women are known to have both a high prevalence of metabolic syndrome (MetS) and vitamin D deficiency (serum 25-hydroxyvitamin D (25OHD) <50 nmol/l). Associations between sleep duration and circulating 25OHD have recently been reported but, to our knowledge, these associations have not been studied in older Chinese populations. We thus investigated whether sleep duration was associated with vitamin D status in a population from Macao, China, and whether sleep duration modified the association between MetS and vitamin D deficiency. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0229642PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055896PMC

Cervical Spine Hyperextension and Altered Posturo-Respiratory Coupling in Patients With Obstructive Sleep Apnea Syndrome.

Front Med (Lausanne) 2020 7;7:30. Epub 2020 Feb 7.

Sorbonne Université, INSERM, UMRS1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, France.

Obstructive sleep apnea syndrome (OSAS) is associated with postural dysfunction characterized by abnormal spinal curvature and disturbance of balance and walking, whose pathophysiology is poorly understood. We hypothesized that it may be the result of a pathological interaction between postural and ventilatory functions. Twelve patients with OSAS (4 women, age 53 years [51-63] (median [quartiles]), apnea hypopnea index 31/h [24-41]) were compared with 12 healthy matched controls. Read More

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http://dx.doi.org/10.3389/fmed.2020.00030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020015PMC
February 2020

The presence of coexisting sleep-disordered breathing among women with hypertensive disorders of pregnancy does not worsen perinatal outcome.

PLoS One 2020 26;15(2):e0229568. Epub 2020 Feb 26.

Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia.

Objective: To determine whether the presence of co-existing sleep-disordered breathing (SDB) is associated with worse perinatal outcomes among women diagnosed with a hypertensive disorder of pregnancy (HDP), compared with normotensive controls.

Study Design: Women diagnosed with HDP (gestational hypertension or preeclampsia) and BMI- and gestation-matched controls underwent polysomnography in late pregnancy to determine if they had coexisting SDB. Fetal heart rate (FHR) monitoring accompanied the sleep study, and third trimester fetal growth velocity was assessed using ultrasound. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0229568PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043804PMC

TLRs and RAGE are elevated in carotid plaques from patients with moderate-to-severe obstructive sleep apnea syndrome.

Sleep Breath 2020 Feb 20. Epub 2020 Feb 20.

Department of Otorhinolaryngology, Faculty of Dental Medicine, Medical University of Warsaw, Warsaw, Poland.

Background: There is growing evidence that obstructive sleep apnea (OSA) promotes vascular endothelial dysfunction and atherogenesis. Pathways that mediate this pathology may include Toll-like receptors (TLRs) and receptor for advanced glycation end products (RAGE) which play a significant role in proinflammatory processes. The aim of this study was to measure the expression of the above-mentioned receptors in relation to OSA severity in carotid plaques obtained during open endarterectomy. Read More

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http://dx.doi.org/10.1007/s11325-020-02029-wDOI Listing
February 2020

Hyperkyphosis and self-reported and objectively measured sleep quality in older men.

PLoS One 2020 11;15(2):e0228638. Epub 2020 Feb 11.

Division of Preventive Medicine, Department of Family Medicine and Public Health, University of California San Diego School of Medicine, La Jolla, California, United States of America.

Objectives: Hyperkyphosis is associated with restricted pulmonary function and posture, potentially contributing to poor sleep. A previous study reported older women with hyperkyphosis had worse self-reported sleep quality, but it is less clear if this association exists in men. We examined the association between hyperkyphosis and subjective and objective sleep quality in a cohort of older men. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0228638PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012394PMC

The Elapsed Time between Dinner and the Midpoint of Sleep is Associated with Adiposity in Young Women.

Nutrients 2020 Feb 5;12(2). Epub 2020 Feb 5.

Department of Nutrition, Food Science and Gastronomy, School of Pharmacy and Food Science, University of Barcelona, 08921 Barcelona, Spain.

Meal timing relative to sleep/wake schedules is relevant in the search for obesity risk factors. However, clock time does not accurately characterize the timing of food intake in the context of internal circadian timing. Therefore, we studied elapsed between dinner and the midpoint of sleep (TDM) as a practical approach to evaluate meal timing relative to internal timing, and its implications on obesity. Read More

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http://dx.doi.org/10.3390/nu12020410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071164PMC
February 2020

Association between upper extremity dysfunction and sleep disturbance in an elderly general population.

SAGE Open Med 2020 21;8:2050312120901584. Epub 2020 Jan 21.

Department of Orthopaedic Surgery, Graduate School of Medicine, Gunma University, Maebashi, Japan.

Objective: Several upper extremity disorders are associated with sleep disturbance in patient populations. This study evaluated the relation between self-assessment of upper extremity function and sleep disturbance in an elderly general population.

Methods: A total of 159 participants (56 men, 103 women, 38-88 years old, mean age of 66. Read More

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http://dx.doi.org/10.1177/2050312120901584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977088PMC
January 2020

Sexual disorders and dyspnoea among women with obstructive sleep apnea.

Adv Med Sci 2020 Mar 27;65(1):189-196. Epub 2020 Jan 27.

Department of Pneumonology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland.

Purpose: We aimed to assess sexual function, sexual distress and the prevalence of female sexual dysfunction (FSD) among women with obstructive sleep apnea syndrome (OSA), and to assess if the presence of OSA and dyspnea influences the prevalence of FSD, body image during sexual activity and sexual function.

Methods: We assessed 23 women with new OSA diagnosis and 23 healthy age and body mass index (BMI) matched controls. Sexual functions were evaluated by Changes in Sexual Functioning Questionnaire (CSFQ), sexual dysfunction was diagnosed based on DSM-5 criteria during the semi-structured sexual interview, whereas body image was evaluated by Body Exposure during Sexual Activities Questionnaire (BESAQ). Read More

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http://dx.doi.org/10.1016/j.advms.2019.12.003DOI Listing

Restless legs syndrome is associated with mast cell activation syndrome.

J Clin Sleep Med 2020 Mar 14;16(3):401-408. Epub 2020 Jan 14.

Institute of Human Genetics, University Hospital Bonn, Bonn, Germany.

Study Objectives: Mast cell activation syndrome (MCAS) is an inflammatory and allergic disorder. We determined the prevalence of restless legs syndrome (RLS) in MCAS because each common syndrome may be inflammatory in nature and associated with dysautonomia.

Methods: Individuals with MCAS were evaluated for RLS by two standard questionnaires. Read More

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http://dx.doi.org/10.5664/jcsm.8216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075100PMC

Hormone replacement therapy after surgery for epithelial ovarian cancer.

Cochrane Database Syst Rev 2020 Jan 28;1:CD012559. Epub 2020 Jan 28.

The Christie NHS Foundation Trust, Gynaecological Oncology, Manchester, UK.

Background: Women who have undergone surgical treatment for epithelial ovarian cancer (EOC) may develop menopausal symptoms due to immediate loss of ovarian function following surgery and chemotherapy. Women may experience vasomotor symptoms, sleep disturbance, difficulty concentrating, sexual dysfunction, vaginal symptoms and accelerated osteoporosis. Although hormone replacement therapy (HRT) is the most effective treatment to relieve these symptoms, its safety has been questioned for women with EOC. Read More

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http://dx.doi.org/10.1002/14651858.CD012559.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027384PMC
January 2020

Right Ventricular Abnormalities on Cardiovascular Magnetic Resonance Imaging in Patients With Sarcoidosis.

JACC Cardiovasc Imaging 2020 Jun 15;13(6):1395-1405. Epub 2020 Jan 15.

Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota. Electronic address:

Objectives: This study aimed to determine the prevalence on cardiac magnetic resonance (CMR) of right ventricular (RV) systolic dysfunction and RV late gadolinium enhancement (LGE), their determinants, and their influences on long-term adverse outcomes in patients with sarcoidosis.

Background: In patients with sarcoidosis, RV abnormalities have been described on many imaging modalities. On CMR, RV abnormalities include RV systolic dysfunction quantified as an abnormal right ventricular ejection fraction (RVEF), and RV LGE. Read More

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http://dx.doi.org/10.1016/j.jcmg.2019.12.011DOI Listing

Eating, sleeping and sexual function disorders in women with polycystic ovary syndrome (PCOS): A systematic review and meta-analysis.

Clin Endocrinol (Oxf) 2020 Apr 3;92(4):338-349. Epub 2020 Feb 3.

Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, Minnesota.

Purpose: We aim to evaluate the association of PCOS with eating, sleeping and sexual function disorders.

Methods: A comprehensive search including MEDLINE, Embase, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and Scopus through 01 August 2018 was conducted for studies reporting the prevalence of any eating, sleep or sexual function disorders in patients with PCOS. Independent reviewers selected studies and extracted data. Read More

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http://dx.doi.org/10.1111/cen.14153DOI Listing

Sleep quality and sex modify the relationships between trait energy and fatigue on state energy and fatigue.

PLoS One 2020 8;15(1):e0227511. Epub 2020 Jan 8.

Department of Physical Therapy, Clarkson University, Potsdam, New York, United States of America.

The objective of this study was to identify the associations between trait energy and fatigue with state energy fatigue, as well as exploring if these relationships interacted with sex and/or sleep quality. The study population included a convenience sample of adults and college students (n ranges from 687 to 694). Key measures were state and trait mental and physical energy and fatigue scales, PSQI (a measure of sleep quality), and sex. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0227511PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949111PMC

Effect of symptoms of climacteric syndrome, depression and insomnia on self-rated work ability in peri- and post-menopausal women in non-manual employment.

Ann Agric Environ Med 2019 Dec 7;26(4):600-605. Epub 2019 Nov 7.

Institute of Statistics and Demography, Collegium of Economic Analysis, SGH School of Economics, Warsaw, Poland.

Objective: The aim of the study was evaluation of the relationship between severity of symptoms of climacteric syndrome, depressive disorders and sleep problems, and the self-rated work ability of peri-menopausal and post-menopausal women in non-manual employment.

Material And Methods: The study included 287 women aged 45-60 years, employed in various institutions as non-manual workers. Work Ability Index, Greene Climacteric Scale, Beck Depression Inventory, and Athens Insomnia Scale were used. Read More

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http://dx.doi.org/10.26444/aaem/112838DOI Listing
December 2019

Clinical profile of comorbid dysmenorrhea and bladder sensitivity: a cross-sectional analysis.

Am J Obstet Gynecol 2020 06 20;222(6):594.e1-594.e11. Epub 2019 Dec 20.

Department of Obstetrics and Gynecology, Northshore University HealthSystem, Evanston, IL; Pritzker School of Medicine, University of Chicago, Chicago, IL.

Background: Antecedents of chronic pelvic pain are not well characterized, but pelvic organ visceral sensitivity is a hallmark of these disorders. Recent studies have identified that some dysmenorrhea sufferers are much more likely to exhibit comorbid bladder hypersensitivity. Presumably, these otherwise healthy women may be at higher risk of developing full-blown chronic bladder pain later in life. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.12.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263950PMC

Isotemporal substitution of inactive time with physical activity and time in bed: cross-sectional associations with cardiometabolic health in the PREDIMED-Plus study.

Int J Behav Nutr Phys Act 2019 12 23;16(1):137. Epub 2019 Dec 23.

Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain.

Background: This study explored the association between inactive time and measures of adiposity, clinical parameters, obesity, type 2 diabetes and metabolic syndrome components. It further examined the impact of reallocating inactive time to time in bed, light physical activity (LPA) or moderate-to-vigorous physical activity (MVPA) on cardio-metabolic risk factors, including measures of adiposity and body composition, biochemical parameters and blood pressure in older adults.

Methods: This is a cross-sectional analysis of baseline data from 2189 Caucasian men and women (age 55-75 years, BMI 27-40 Kg/m) from the PREDIMED-Plus study (http://www. Read More

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http://dx.doi.org/10.1186/s12966-019-0892-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929461PMC
December 2019

Neurokinin B and Neurokinin-3 Receptor Signaling: Promising Developments in the Management of Menopausal Hot Flushes.

Semin Reprod Med 2019 05 23;37(3):125-130. Epub 2019 Dec 23.

Section of Endocrinology and Investigative Medicine, Imperial College London, London, United Kingdom.

Vasomotor symptoms, including hot flushes and night sweats, pose a significant symptomatic burden to women undergoing menopause, and negatively impact on both their physical and psychological well-being. Management of these symptoms can be challenging, with the use of conventional hormone replacement therapy limited by duration of treatment and clinical contraindications. Recent advances in our understanding of the neuroendocrine regulation of the reproductive axis and thermoregulation postmenopause has helped identify a promising new therapeutic target to ameliorate hot flushes. Read More

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http://dx.doi.org/10.1055/s-0039-3400241DOI Listing

Absenteeism during Menstruation among Nursing Students in Spain.

Int J Environ Res Public Health 2019 12 19;17(1). Epub 2019 Dec 19.

Department of Nursing, Physiotherapy and Occupational Therapy, University of Castilla-La-Mancha, Ciudad Real,13071 Ciudad Real, Spain.

Absenteeism can clearly have a negative impact on academic performance among university students. Certain experiences or symptoms such as menstrual pain are very common in women and can lead to absenteeism. The current study was aimed at examining the presence of menstrual experiences or symptoms and their impact upon absenteeism among healthy (illness-free) female university nursing students in Spain. Read More

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http://dx.doi.org/10.3390/ijerph17010053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981649PMC
December 2019

Beyond the bladder: poor sleep in women with overactive bladder syndrome.

Am J Obstet Gynecol 2020 06 10;222(6):600.e1-600.e13. Epub 2019 Dec 10.

Department of Medicine, University of California San Francisco, CA.

Background: Nocturnal bladder symptoms and sleep disruption commonly coexist in middle-aged and older women. Although sleep disruption is often attributed to nocturnal bladder symptoms in women with overactive bladder syndrome, nonbladder factors also may influence sleep in this population. Many women with overactive bladder are eager to identify nonpharmacologic strategies for both bladder symptoms and sleep disruption, given the potential adverse effects of sedative and anticholinergic bladder medications in this population. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263944PMC

State of Mental Health and Associated Factors in Nursing Students from Southeastern Iran.

Invest Educ Enferm 2019 Sep;37(3)

Shiraz University of Medical Sciences, Iran.

Objectives: To evaluate the state of mental health and its relation with associated factors among nursing students.

Methods: A cross-sectional study was conducted with 130 students from the Nursing and Midwifery College affiliated to the University of Medical Sciences of Shiraz (Iran). Data was collected through a document that included information on the demographic characteristics, the mean grades of the practical assignments and of the total (practical and theoretical assignments), and the Goldberg Health Questionnaire (GHQ-28) that measures symptoms grouped into four dimensions (somatic symptoms, anxiety and insomnia, social dysfunction, and depression). Read More

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http://dx.doi.org/10.17533/udea.iee.v37n3e04DOI Listing
September 2019

The Effects of Melatonin on the Descending Pain Inhibitory System and Neural Plasticity Markers in Breast Cancer Patients Receiving Chemotherapy: Randomized, Double-Blinded, Placebo-Controlled Trial.

Front Pharmacol 2019 22;10:1382. Epub 2019 Nov 22.

Post-graduate Program in Pharmacology and Therapeutics, Department of Pharmacology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil.

Adjuvant chemotherapy for breast cancer (ACBC) has been associated with fatigue, pain, depressive symptoms, and disturbed sleep. And, previous studies in non-cancer patients showed that melatonin could improve the descending pain modulatory system (DPMS). We tested the hypothesis that melatonin use before and during the first cycle of ACBC is better than placebo at improving the DPMS function assessed by changes in the 0-10 Numerical Pain Scale (NPS) during the conditioned pain modulating task (CPM-task) (primary outcome). Read More

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http://dx.doi.org/10.3389/fphar.2019.01382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883914PMC
November 2019

Lack of Association between Periodic Limb Movements during Sleep and Neuroimaging Signatures of Cerebral Small Vessel Disease in Stroke-Free Community-Dwelling Older Adults. The Atahualpa Project.

J Stroke Cerebrovasc Dis 2020 Feb 4;29(2):104497. Epub 2019 Dec 4.

Sleep Disorders Center, Mayo Clinic College of Medicine, Jacksonville, Florida.

Background: Evidence of the relationship between periodic limb movements during sleep (PLMS) and cerebral small vessel disease (cSVD) is limited and inconsistent. Here, we aimed to assess the independent association between PLMS and the different neuroimaging signatures of cSVD.

Methods: Atahualpa residents aged more than or equal to 60 years enrolled in the Atahualpa Project undergoing polysomnography and MRI with time intervals less than or equal to 6 months were included. Read More

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2019.104497DOI Listing
February 2020

Association of Night Eating with Depression and Depressive Symptoms in Korean Women.

Int J Environ Res Public Health 2019 12 1;16(23). Epub 2019 Dec 1.

Department of Food and Nutrition, Inha University, Incheon 22212, Korea.

This study examined the associations of night eating with depression and depressive symptoms in Korean adults. The study used a nationally representative sample of 31,690 Korean adults (≥19 years old) from the Korea National Health and Nutrition Examination Survey from 2008 to 2013. The participants were divided into two groups based on status of night eating: night eaters (consuming ≥25% of total daily energy intake between 21:00 and 06:00) and non-night eaters. Read More

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http://dx.doi.org/10.3390/ijerph16234831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926998PMC
December 2019

Objective short sleep duration increases the risk of all-cause mortality associated with possible vascular cognitive impairment.

Sleep Health 2020 02 21;6(1):71-78. Epub 2019 Nov 21.

Sleep Research & Treatment Center, Pennsylvania State University College of Medicine, Penn State Milton S. Hershey Medical Center, Hershey, PA.

Objectives: Cognitive impairment is a leading cause of disability worldwide, and cardiometabolic conditions are key contributors to its development. Short sleep is also a potential contributor to brain health; however, its role in predicting mortality remains poorly understood. We investigated whether objective short sleep duration increases the risk of all-cause mortality associated with coexisting cognitive impairment and cardiometabolic conditions, i. Read More

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http://dx.doi.org/10.1016/j.sleh.2019.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995415PMC
February 2020
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Cocaine Use and Pulmonary Hypertension.

Am J Cardiol 2020 01 19;125(2):282-288. Epub 2019 Nov 19.

Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas; Division of Cardiovascular Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas; Cardiovascular Institute, Mount Sinai Hospital, New York, New York; Advanced Cardiovascular Imaging Laboratory, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland. Electronic address:

Evidence linking cocaine to the risk of pulmonary hypertension (PH) is limited and inconsistent. We examined whether cocaine use, in the absence of other known causes of PH, was associated with elevated systolic pulmonary artery pressure (sPAP) and increased probability of PH. We compared patients with documented cocaine use to a randomly selected age, sex, and race-matched control group without history of cocaine use. Read More

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http://dx.doi.org/10.1016/j.amjcard.2019.10.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920567PMC
January 2020

The Association between Sleep Duration and Metabolic Syndrome: The NHANES 2013/2014.

Nutrients 2019 Oct 26;11(11). Epub 2019 Oct 26.

Department of Epidemiology, School of Public Health, Indiana University, Bloomington, IN 47404, USA.

Background: We aimed to assess the association of sleep with metabolic syndrome in the 2013/2014 National Health and Nutrition Examination Survey (NHANES).

Methods: Sample size included 2737 out of 2013 and 2014 NHANES surveys. Cross-sectional study of metabolic syndrome and sleep duration was conducted. Read More

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http://dx.doi.org/10.3390/nu11112582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893635PMC
October 2019
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