2,868 results match your criteria Sleep Dysfunction in Women


Sleep Quality, Duration, and Associated Sexual Function at Older Age: Findings from the English Longitudinal Study of Ageing.

J Sex Med 2019 Feb 14. Epub 2019 Feb 14.

Department of Behavioural Science and Health, University College London, London, United Kingdom.

Introduction: One factor that may plausibly be associated with sexual dysfunction is sleep disturbance. Like sexual problems, complaints of sleep disturbance increase with age and are commonly reported by older adults.

Aims: To examine associations between sleep quality, duration, and a range of sexual problems in a large, representative sample of older adults. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jsxm.2019.01.005DOI Listing
February 2019
3.151 Impact Factor

MIBG Myocardial Scintigraphy Identifies Premotor PD/DLB During a Negative DAT Scan Period: Second Report.

Mov Disord Clin Pract 2019 Jan 9;6(1):46-50. Epub 2018 Nov 9.

Gastroenterology, Internal Medicine, Sakura Medical Center Toho University Sakura Japan.

Objectives: Neuroimaging markers for Parkinson's disease (PD)/dementia with Lewy bodies (DLB) include dopamine transporter (DAT) scanning and metaiodobenzylguanidine (MIBG) myocardial scintigraphy. It is unknown which marker is useful to identify the premotor phase PD/DLB. We reported four patients who, during a negative DAT scan period, had a positive MIBG result that suggested premotor PD/DLB. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mdc3.12697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335543PMC
January 2019
1 Read

Lifetime discrimination, global sleep quality, and inflammation burden in a multiethnic sample of middle-aged adults.

Cultur Divers Ethnic Minor Psychol 2019 Jan;25(1):82-90

Department of Social and Behavioral Sciences, Harvard University.

Objective: Despite considerable evidence that greater exposure to discrimination over the life course increases risk for systemic inflammation, little is known about the mechanisms responsible for this association. Here we examine the role of global sleep quality as a potential pathway by which self-reported experiences of discrimination contribute to inflammatory dysfunction in a multiethnic sample of middle-aged adults.

Method: Participants were 300 adults (36-85 years; 65% women) from Milwaukee, Wisconsin, a subset of the Midlife in the United States Study 2 (2004-2006). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1037/cdp0000233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369702PMC
January 2019

[Cognitive and emotional disorders in university students and teachers: the possibility of treatment with recognan (citicoline)].

Zh Nevrol Psikhiatr Im S S Korsakova 2018 ;118(12):11-18

Pirogov Russian National Research Medical University, Moscow, Russia.

Aim: To study the efficacy of recognan (citicoline) in treatment of cognitive, emotional, autonomic, asthenic disorders in university students and teachers.

Material And Methods: Fifty-eight subjects (17 men and 41 women), mean age 27.75±12. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17116/jnevro201811812111DOI Listing
January 2018
7 Reads

Effect of Foeniculum Vulgare (Fennel) on Sleep Quality of Menopausal Women: A Double-blinded, Randomized Placebo-controlled Trial.

J Menopausal Med 2018 Dec 31;24(3):204-209. Epub 2018 Dec 31.

Department of Nursing and Midwifery, Razi School of Nursing and Midwifery, Kerman University of Medical Sciences, Kerman, Iran.

Objectives: Aim of present study was designed to investigate the soporific effect of fennel among menopausal women.

Methods: The present double-blinded and placebo-controlled trial examined the fennel effect on Pittsburgh Sleep Quality Index (PSQI). Total score and relevant 7 components, including sleep duration, sleep latency, use of sleeping medication, subjective sleep quality, sleep disturbances, daytime dysfunction and habitual sleep efficiency among 50 menopausal women compared to control group within a 12-week follow-up. Read More

View Article

Download full-text PDF

Source
https://synapse.koreamed.org/DOIx.php?id=10.6118/jmm.2018.24
Publisher Site
http://dx.doi.org/10.6118/jmm.2018.24.3.204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336564PMC
December 2018
2 Reads

Potency of descending pain modulatory system is linked with peripheral sensory dysfunction in fibromyalgia: An exploratory study.

Medicine (Baltimore) 2019 Jan;98(3):e13477

Post-Graduate Program in Medical Sciences, Medical Engineering Service.

Fibromyalgia (FM) is characterized by chronic widespread pain whose pathophysiological mechanism is related to central and peripheral nervous system dysfunction. Neuropathy of small nerve fibers has been implicated due to related pain descriptors, psychophysical pain, and neurophysiological testing, as well as skin biopsy studies. Nevertheless, this alteration alone has not been previously associated to the dysfunction in the descending pain modulatory system (DPMS) that is observed in FM. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000013477DOI Listing
January 2019
3 Reads

Roles of oestradiol receptor alpha and beta against hypertension and brain mitochondrial dysfunction under intermittent hypoxia in female rats.

Acta Physiol (Oxf) 2019 Jan 11:e13255. Epub 2019 Jan 11.

Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Quebec City, Quebec, Canada.

Aim: Chronic intermittent hypoxia (CIH) induces systemic (hypertension) and central alterations (mitochondrial dysfunction underlying cognitive deficits). We hypothesized that agonists of oestradiol receptors (ER) α and β prevent CIH-induced hypertension and brain mitochondrial dysfunction.

Methods: Ovariectomized female rats were implanted with osmotic pumps delivering vehicle (Veh), the ERα agonist propylpyraoletriol (PPT - 30 μg/kg/day) or the ERβ agonist diarylpropionitril (DPN - 100 μg/kg/day). Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/apha.13255
Publisher Site
http://dx.doi.org/10.1111/apha.13255DOI Listing
January 2019
5 Reads

Aberrant Cerebral Activity in Early Postmenopausal Women: A Resting-State Functional Magnetic Resonance Imaging Study.

Front Cell Neurosci 2018 26;12:454. Epub 2018 Nov 26.

Department of Radiology, Xinqiao Hosptial, Third Military Medical University, Chongqing, China.

: Early postmenopausal women frequently suffer from cognitive impairments and emotional disorders, such as lack of attention, poor memory, deficits in executive function and depression. However, the underlying mechanisms of these impairments remain unclear. : Forty-three early postmenopausal women and forty-four age-matched premenopausal controls underwent serum sex hormone analysis, neuropsychological testing and resting-state functional magnetic resonance imaging (rs-fMRI). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fncel.2018.00454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275219PMC
November 2018
2 Reads

Migraine and Markers of Carotid Atherosclerosis in Middle-Aged Women: A Cross-Sectional Study.

Headache 2019 Jan 5;59(1):77-85. Epub 2018 Dec 5.

Division of Neurology, Hospital Universitário Oswaldo Cruz of the Universidade de Pernambuco, Recife, Brazil.

Objective: This study evaluated the association between migraine and the markers of carotid artery disease.

Background: Migraine increases the risk of cardiovascular events, but its relationship with vascular dysfunction is unclear.

Methods: In this cross-sectional study, middle-aged women with no known cardiovascular diseases underwent clinical, neurological, and laboratory evaluations; pulse wave velocity (PWV) assessment; and carotid artery ultrasonography. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/head.13460DOI Listing
January 2019
1 Read

Lack of associations between thyroid function and obstructive sleep apnea severity in adults with prediabetes and diabetes mellitus.

Sleep Breath 2018 Nov 19. Epub 2018 Nov 19.

Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama 6 Road, Bangkok, 10400, Thailand.

Purpose: Hypothyroidism is associated with a high frequency of obstructive sleep apnea (OSA). However, the prevalence of OSA in hypothyroid patients is not different from the general population in many reports. The importance of thyroid function screening in sleep-disordered breathing is still controversial. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11325-018-1756-xDOI Listing
November 2018
2 Reads

Sex-Specific Differences in Risk Factors for Development of Heart Failure in Women.

Heart Fail Clin 2019 Jan 24;15(1):1-8. Epub 2018 Oct 24.

The Ohio State University, 410 West 10th Avenue, Columbus, OH 43210, USA.

Sex specific differences exist in the impact of risk factors for the development of heart failure (HF). Addressing these differences can have an impact on prevention of HF. This article reviews sex-specific risk factors associated with development of HF. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hfc.2018.08.001DOI Listing
January 2019
20 Reads

Gender and onset age related-differences of non-motor symptoms and quality of life in drug-naïve Parkinson's disease.

Clin Neurol Neurosurg 2018 Dec 2;175:124-129. Epub 2018 Nov 2.

Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, China. Electronic address:

Objective: This study aims to explore the gender and onset age-related differences of non-motor symptoms (NMS) and the determinants of quality of life (QoL) in a large cohort of Chinese drug-naïve Parkinson's disease (PD) patients.

Patients And Methods: A cross-sectional analysis of 569 drug-naïve PD patients was conducted. The frequency and severity of each NMS was evaluated by Non-Motor Symptom Scale (NMSS), which consists of 9 subdomains. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clineuro.2018.11.001DOI Listing
December 2018
3 Reads

[Effectiveness of Laparoscopic Sleeve Gastrectomy in Treating Obesity and Its Co-morbidities].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2018 Oct;40(5):610-616

Department of Cardiology,PUMC Hospital, CAMS and PUMC,Beijing 100730,China.

Objective To analyze the effectiveness and safety of laparoscopic sleeve gastrectomy (LSG) in treating obesity and its co-morbidities.Methods The clinical data of obese patients undergoing LSG in Peking Union Medical College Hospital from August 2012 to August 2017 were retrospectively analyzed. Medium-term outcome measures included excess weight loss (%EWL),co-morbidity improvement,and complications. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3881/j.issn.1000-503X.10717DOI Listing
October 2018
12 Reads

Associations Between Breast Cancer Survivorship and Adverse Mental Health Outcomes: A Systematic Review.

J Natl Cancer Inst 2018 Dec;110(12):1311-1327

Department of Non-Communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.

Background: We aimed to systematically review the evidence on adverse mental health outcomes in breast cancer survivors (≥1 year) compared with women with no history of cancer.

Methods: Studies were identified by searching MEDLINE, PsycINFO, the Cumulative Index to Nursing and Allied Health Literature, and the Social Sciences Citation Index, and through backward citation tracking. Two researchers selected the studies, extracted data, and assessed the risk of bias. Read More

View Article

Download full-text PDF

Source
https://academic.oup.com/jnci/advance-article/doi/10.1093/jn
Publisher Site
http://dx.doi.org/10.1093/jnci/djy177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292797PMC
December 2018
6 Reads

Sleep, Health, and Metabolism in Midlife Women and Menopause: Food for Thought.

Obstet Gynecol Clin North Am 2018 Dec 25;45(4):679-694. Epub 2018 Oct 25.

Department of Psychiatry and Connors Center for Women's Health, Brigham and Women's Hospital, Dana Farber Cancer Institute, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

Sleep and metabolism are essential components of health. Metabolic health depends largely on individual's lifestyle. Disturbances in sleep health, such as changes in sleep patterns that are associated with menopause/reproductive aging and chronologic aging, may have metabolic health consequences. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08898545183006
Publisher Site
http://dx.doi.org/10.1016/j.ogc.2018.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338227PMC
December 2018
12 Reads

Depression During and After the Perimenopause: Impact of Hormones, Genetics, and Environmental Determinants of Disease.

Obstet Gynecol Clin North Am 2018 Dec 25;45(4):663-678. Epub 2018 Oct 25.

Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, 3535 Market Street, Philadelphia, PA, 19104, USA; Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, 3535 Market Street, Philadelphia, PA, 19104, USA; Penn PROMOTES Research on Sex and Gender in Health, University of Pennsylvania, 3535 Market Street, Philadelphia, PA, 19104, USA.

Vulnerability to depression is increased across the menopause transition and in the early years after the final menstrual period. Clinicians should systematically screen women in this age group; if depressive symptoms or disorder are present, treatment of depression should be initiated. Potential treatments include antidepressants for moderate to severe symptoms, psychotherapy to target psychological and interpersonal factors, and hormone therapy for women with first-onset major depressive disorder or elevated depressive symptoms and at low risk for adverse effects. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08898545183006
Publisher Site
http://dx.doi.org/10.1016/j.ogc.2018.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226029PMC
December 2018
7 Reads

Onset of the Menopause Transition: The Earliest Signs and Symptoms.

Obstet Gynecol Clin North Am 2018 Dec 25;45(4):585-597. Epub 2018 Oct 25.

Department of Obstetrics/Gynecology, University of Pennsylvania School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104, USA; Department of Psychiatry, University of Pennsylvania School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104, USA.

Although more than 80% of women experience some degree of psychological or physical symptoms around menopause, both women and clinicians have misconceptions about how hormonal changes relate to menopausal symptoms and psychological conditions. Recently, several large-scale, longitudinal studies have been conducted to better characterize symptoms and changes that occur around menopause. This article offers current evidence for symptoms that occur in the early menopause transition, including vasomotor symptoms, mood changes, sleep problems, and changes in sexual functioning. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08898545183006
Publisher Site
http://dx.doi.org/10.1016/j.ogc.2018.07.002DOI Listing
December 2018
6 Reads

Menopause.

Prim Care 2018 Dec 5;45(4):625-641. Epub 2018 Oct 5.

Department of Family Medicine and Community Health, University of Wisconsin School of Medicine and Public Health, 1100 Delaplaine, Madison, WI 53715, USA.

The menopausal transition is a time when many physical and psychological changes are occurring for women. Women may experience irregular menses, vasomotor symptoms, sleep disruption, mood disorders as well as genitourinary symptoms. Despite irregular menstrual cycles, some women can still conceive. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00954543183007
Publisher Site
http://dx.doi.org/10.1016/j.pop.2018.08.001DOI Listing
December 2018
10 Reads

Protocol for the "Chemobrain in Motion - study" (CIM - study): a randomized placebo-controlled trial of the impact of a high-intensity interval endurance training on cancer related cognitive impairments in women with breast cancer receiving first-line chemotherapy.

BMC Cancer 2018 Nov 6;18(1):1071. Epub 2018 Nov 6.

Department of Molecular and Cellular Sport Medicine, Institute of Cardiovascular Research and Sports Medicine, German Sport University Cologne, Am Sportpark Müngersdorf 6, 50933, Cologne, Germany.

Background: Up to 80% of breast cancer patients suffer from Cancer Related Cognitive Impairments (CRCI). Exercise is suggested as a potential supportive care option to reduce cognitive decline in cancer patients. This study will investigate the effects of a high-intensity interval endurance training (HIIT) on CRCI in breast cancer patients. Read More

View Article

Download full-text PDF

Source
https://bmccancer.biomedcentral.com/articles/10.1186/s12885-
Publisher Site
http://dx.doi.org/10.1186/s12885-018-4992-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220507PMC
November 2018
13 Reads

Linking sleep disturbance to idiopathic male infertility.

Sleep Med Rev 2018 12 3;42:149-159. Epub 2018 Aug 3.

CIRUS, Centre for Sleep and Chronobiology, Woolcock Institute of Medical Research, Sydney, New South Wales, Australia; Discipline of Sleep Medicine, Sydney Medical School, University of Sydney, New South Wales, Australia; Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Camperdown, Sydney, New South Wales, Australia.

Recently published data suggests that male fertility has declined over the past four decades. The reasons for the decline are unclear with up to 50% of cases of male infertility remaining unexplained (idiopathic male infertility). Whilst environmental factors and rising rates of obesity have been implicated, there is now growing evidence that sleep disturbance may be an independent causative factor. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10870792173015
Publisher Site
http://dx.doi.org/10.1016/j.smrv.2018.07.006DOI Listing
December 2018
3 Reads

Poor Sleep Quality Is Associated with Higher Hemoglobin A1c in Pregnant Women: A Pilot Observational Study.

Int J Environ Res Public Health 2018 10 18;15(10). Epub 2018 Oct 18.

Professional and Medical Education & Internal Medicine, Meharry Medical College, 1005 Dr. D.B. Todd Jr. Boulevard, Nashville, TN 37208, USA.

We hypothesized that poor sleep quality exacerbates glucose intolerance manifested as elevated glycosylated hemoglobin (HbA1c), which increases the risk for gestational diabetes. To test this, 38 pregnant and 22 non-pregnant (age, 18⁻35 years; body-mass index, 20⁻35 kg/m²) otherwise healthy women were enrolled in the study. Sleep quality was assessed during gestational week 24 (pregnant), or outside of the menstrual period (non-pregnant), using qualitative (Pittsburgh Sleep Quality Index) and objective (actigraphic wrist-watch) measures. Read More

View Article

Download full-text PDF

Source
http://www.mdpi.com/1660-4601/15/10/2287
Publisher Site
http://dx.doi.org/10.3390/ijerph15102287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210387PMC
October 2018
5 Reads

Decreased serum levels of CTRP12/adipolin in patients with coronary artery disease in relation to inflammatory cytokines and insulin resistance.

Cytokine 2019 Jan 15;113:326-331. Epub 2018 Oct 15.

Department of Clinical Biochemistry, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran. Electronic address:

Coronary artery disease (CAD) is the leading cause of death worldwide. Atherosclerosis as the main underlying mechanism of CAD is associated with inflammation and adipose tissue dysfunction. C1q/TNF-related protein12 (CTRP12) is a newly discovered adipokine which is a paralog of adiponectin. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10434666183038
Publisher Site
http://dx.doi.org/10.1016/j.cyto.2018.09.019DOI Listing
January 2019
11 Reads
3.510 Impact Factor

Fatigue after breast cancer treatment: Biobehavioral predictors of fatigue trajectories.

Health Psychol 2018 Nov;37(11):1025-1034

Division of Cancer Prevention and Control Research, Jonsson Comprehensive Cancer Center at UCLA.

Objective: Fatigue is a common side effect of cancer treatment, but there is considerable variability in fatigue severity and persistence among survivors. This study aimed to characterize longitudinal trajectories of fatigue after breast cancer treatment and to identify predictors of varying fatigue trajectories.

Methods: Women (N = 191) from the Mind-Body Study completed assessments after primary treatment for early stage breast cancer and at regular follow-ups that occurred up to 6 years after treatment (M = 4. Read More

View Article

Download full-text PDF

Source
http://doi.apa.org/getdoi.cfm?doi=10.1037/hea0000652
Publisher Site
http://dx.doi.org/10.1037/hea0000652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372460PMC
November 2018
26 Reads

Clinical outcomes of intravesical injections of botulinum toxin type A in patients with refractory idiopathic overactive bladder.

Pharmacol Rep 2018 Dec 2;70(6):1133-1138. Epub 2018 Aug 2.

Department of General and Oncological Urology, Nicolaus Copernicus Hospital, Toruń, Poland; Department of General and Oncologic Urology, Nicolaus Copernicus University, Bydgoszcz, Poland.

Background: The aim of the study was to estimated the clinical efficacy of intravesical injections of botulinum toxin type A (BTX-A) in refractory idiopathic overactive bladder (OAB) in the aspect of the quality of life. The potential mechanism of BTX-A actions were described.

Methods: The study was performed on 22 women with idiopathic OAB who underwent intravesical injection of BTX-A. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pharep.2018.08.002DOI Listing
December 2018
1 Read

Correlations between the active straight leg raise, sleep and somatosensory sensitivity during pregnancy with post-partum lumbopelvic pain: an initial exploration.

Scand J Pain 2018 Oct 11. Epub 2018 Oct 11.

Center for Neuroplasticity and Pain (CNAP), SMI, Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, Denmark.

Background and aims For some women, lumbopelvic pain (LPP) developed during pregnancy becomes a continuing post-partum problem. Increased understanding of potential prognostic factors is required. This study investigated whether active straight leg raise (ASLR), sleep dysfunction and pressure pain sensitivity during pregnancy are correlated with LPP intensity and quality, disability, and physical health-related quality of life (HRQoL) post-partum. Read More

View Article

Download full-text PDF

Source
http://www.degruyter.com/view/j/sjpain.ahead-of-print/sjpain
Publisher Site
http://dx.doi.org/10.1515/sjpain-2018-0081DOI Listing
October 2018
2 Reads

Sedentary time, physical activity, and sleep quality in fibromyalgia: The al-Ándalus project.

Scand J Med Sci Sports 2019 Feb 30;29(2):266-274. Epub 2018 Oct 30.

Department of Physical Education, Faculty of Education Sciences, University of Cádiz, Cádiz, Spain.

Purpose: To get insight into the potential significance of objectively measured sedentary time (ST), and physical activity (PA) intensity levels on sleep quality (SQ) in women with fibromyalgia; and to assess whether those who meet moderate-to-vigorous PA (MVPA) recommendations have better SQ than their counterparts.

Methods: Four-hundred and nine women with fibromyalgia (age range 30-65 years old) from Andalusia (southern Spain) were included in this cross-sectional study. Sedentary time, PA intensity levels (light, moderate, and MVPA), and total PA were assessed with accelerometers during seven consecutive days. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/sms.13318DOI Listing
February 2019
3 Reads
2.900 Impact Factor

Female Sex and Alzheimer's Risk: The Menopause Connection.

J Prev Alzheimers Dis 2018 ;5(4):225-230

Lisa Mosconi, PhD, Department of Neurology, Weill Cornell Medicine, 428 East 72nd St, Suite 500, Room 407, New York, NY, 10021; Tel: (212) 746-4624, Email:

Along with advanced age and apolipoprotein E (APOE)-4 genotype, female sex is a major risk factor for developing late-onset Alzheimer's disease (AD). Considering that AD pathology begins decades prior to clinical symptoms, the higher risk in women cannot simply be accounted for by their greater longevity as compared to men. Recent investigation into sex-specific pathophysiological mechanisms behind AD risk has implicated the menopause transition (MT), a midlife neuroendocrine transition state unique to females. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14283/jpad.2018.34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198681PMC
January 2018
4 Reads

Obstructive sleep apnea and the metabolic syndrome: The road to clinically-meaningful phenotyping, improved prognosis, and personalized treatment.

Sleep Med Rev 2018 12 3;42:211-219. Epub 2018 Sep 3.

Sleep Research and Treatment Center, Department of Psychiatry, Pennsylvania State University College of Medicine, Hershey, PA, USA.

Obstructive sleep apnea (OSA) is an increasingly prevalent sleep disorder characterized by upper airway obstruction during sleep, resulting in breathing pauses, intermittent hypoxia, and fragmented sleep. In parallel, the constellation of adverse health outcomes associated with prolonged obesity, such as insulin resistance, elevated blood pressure, triglycerides, and reduced high-density lipoprotein cholesterol - termed metabolic syndrome -raises the risk of cardiovascular morbidity and mortality, type 2 diabetes, and all-cause mortality. Affecting 35-40% of U. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.smrv.2018.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221996PMC
December 2018
4 Reads

Endothelial dysfunction is associated with impaired lung function in two independent community cohorts.

Respir Med 2018 Oct 12;143:123-128. Epub 2018 Sep 12.

Division of Family Medicine and Primary Care, Department of Neurobiology, Care Sciences and Society, Karolinska Institute, Huddinge, Sweden; Dalarna County Council, Norslund-Svärdsjö Primary Health Care Center, Falun, Sweden; School of Health and Social Sciences, Dalarna University, Falun, Sweden. Electronic address:

Background: Prior studies investigating the association between endothelial dysfunction and impaired lung function have been small and inconsistent. The primary aim was to investigate the association between endothelial function and lung function in two community-based cohorts.

Methods: We used a discovery/replication approach to study the association between endothelial function and lung function in the Prospective investigation of Obesity, Energy and Metabolism (POEM, discovery cohort, n = 490, mean age 50. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S09546111183029
Publisher Site
http://dx.doi.org/10.1016/j.rmed.2018.09.009DOI Listing
October 2018
5 Reads

Intersection between gonadal function and vascular aging in women.

Authors:
Kerrie L Moreau

J Appl Physiol (1985) 2018 Dec 13;125(6):1881-1887. Epub 2018 Sep 13.

Division of Geriatric Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus , Aurora, Colorado.

Vascular aging, characterized by endothelial dysfunction and large elastic arterial stiffening, is a major risk factor for age-associated cardiovascular disease (CVD). Although women have a lower prevalence of CVD until midlife, prevalence rates increase rapidly coincident with the menopausal transition to match those observed in men. The menopausal transition, or perimenopause, is a chaotic period that is associated with increased symptoms (e. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/japplphysiol.00117.2018DOI Listing
December 2018

What Have We Learned From the Osaka Study?

Cornea 2018 Nov;37 Suppl 1:S62-S66

Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.

Purpose: To summarize the results of a cross-sectional epidemiologic study of Japanese office workers who use visual display terminals (VDTs).

Methods: Workers in a pharmaceutical company head office were recruited. Participants were requested to complete a questionnaire on symptoms of dry eye disease (DED) and evaluations using the Work Limitations Questionnaire, International Physical Activity Questionnaire, Subjective Happiness Scale, and Pittsburgh Sleep Quality Index. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/ICO.0000000000001731DOI Listing
November 2018
16 Reads

Change in the prevalence asthma, rhinitis and respiratory symptom over a 20 year period: associations to year of birth, life style and sleep related symptoms.

BMC Pulm Med 2018 Sep 12;18(1):152. Epub 2018 Sep 12.

Department of Medical Sciences, Respiratory, Allergy and Sleep Medicine, Uppsala University, Uppsala, Sweden.

Background: The aim of this investigation was to study change in adults over a 20 year period in the prevalence of respiratory symptoms and disorders and its association to year of birth, life style and sleep related variables.

Method: Adults 20-44 years of age, 6085 women and 5184 men, were randomly selected from seven centres in Northern Europe and followed for 20 years. The number of participants in the first survey was 21,595 and 11,269 participated in all three surveys. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12890-018-0690-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136212PMC
September 2018
11 Reads

Relation of Obstructive Sleep Apnea to Risk of Hospitalization in Patients With Heart Failure and Preserved Ejection Fraction from the National Inpatient Sample.

Am J Cardiol 2018 Aug 20;122(4):612-615. Epub 2018 Jun 20.

Department of Medicine - Rochester Regional Health, Unity Hospital, Rochester, New York; Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York; School of Health Sciences, Rochester Institute of Technology, Rochester, New York.

Obstructive Sleep Apnea (OSA) increases the risk of diastolic dysfunction and heart failure. The impact of OSA on hospitalization for heart failure with preserved ejection fraction (HFpEF) is not well elucidated. We used data from the National Inpatient Sample for the years 2012 to 2014. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amjcard.2018.04.052DOI Listing
August 2018
10 Reads

A Systematic Review and Meta-analysis on the Effect of Herbal Medicine to Manage Sleep Dysfunction in Peri- and Postmenopause.

J Menopausal Med 2018 Aug 31;24(2):92-99. Epub 2018 Aug 31.

Department of Parasitology and Mycology, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.

Objectives: Some conventional medications used to treat insomnia, such as benzodiazepine, non-benzodiazepine, and hormone therapy, are associated with side effects. Therefore, there is a growing interest in the use of herbal medicine. The aim of this systematic review is to assess the effects herbal medicines have on sleep disorders of peri- and postmenopausal women. Read More

View Article

Download full-text PDF

Source
https://synapse.koreamed.org/DOIx.php?id=10.6118/jmm.2018.24
Publisher Site
http://dx.doi.org/10.6118/jmm.2018.24.2.92DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127017PMC
August 2018
4 Reads

Long-Term Effects of Tai Chi Intervention on Sleep and Mental Health of Female Individuals With Dependence on Amphetamine-Type Stimulants.

Front Psychol 2018 20;9:1476. Epub 2018 Aug 20.

Department of Movement and Sport Sciences, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium.

Previous studies provide evidence that Tai Chi (TC) can reduce the symptoms of sleep problems and be of benefit for the rehabilitation of substance abusers. In this study, we investigated if TC practice can improve sleep quality and mood of females who are dependent on amphetamine-type stimulant (ATS). Eighty subjects were randomly assigned to TC intervention and standard care (SC) for 6 months. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fpsyg.2018.01476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110176PMC
August 2018
4 Reads

Impact of breast cancer on prospective memory functioning assessed by virtual reality and influence of sleep quality and hormonal therapy: PROSOM-K study.

BMC Cancer 2018 Sep 3;18(1):866. Epub 2018 Sep 3.

Normandie Université, UNICAEN, PSL Université, EPHE, INSERM, U1077, CHU de Caen, Neuropsychologie et Imagerie de la Mémoire Humaine, 14000, Caen, France.

Background: Breast cancer (BC) is the most frequent cancer in women with more than 70% of BC patients being treated with hormonal therapy (HT). Among these patients, some report difficulties in remembering what they are supposed to do at the right moment, referring to prospective memory (PM). PM is essential for autonomy and medical adherence of patients, and requires an ecological assessment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12885-018-4762-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122719PMC
September 2018
6 Reads

Sleep-disordered breathing, neuroendocrine function, and clinical SUDEP risk in patients with epilepsy.

Epilepsy Behav 2018 10 31;87:78-82. Epub 2018 Aug 31.

Comprehensive Epilepsy and Sleep Center, Department of Neurology, Columbia University Medical Center New York, NY, United States.

Introduction: Sudden unexpected death in epilepsy (SUDEP) is a major contributor to epilepsy-related mortality. It is associated with nocturnal seizures and centrally mediated postictal cardiorespiratory dysfunction (CRD), but mechanisms and contributors remain poorly understood.

Methods: We performed a prospective, cross-sectional, observational pilot study in the Columbia University Medical Center (CUMC) adult epilepsy monitoring unit (EMU) to explore relationships between periictal CRD, sleep-disordered breathing (SDB), neuroendocrine function, and clinical SUDEP risk. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yebeh.2018.07.011DOI Listing
October 2018
2 Reads

Effects of a 10-week functional training programme on pain, mood state, depression, and sleep in healthy older adults.

Psychogeriatrics 2018 Jul;18(4):292-298

Department of Corporal Expression, University of Jaen, Jaen, Spain.

Background: The purpose of this study was to analyze the effects of a 10-week functional training (FT) programme on pain, mood state, sleep, and depression in healthy older adults.

Method: A group of 38 older adults (32 women, 6 men) voluntarily participated in this study. Participants were randomly assigned to either the experimental group (n = 20; age: 75. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/psyg.12323DOI Listing
July 2018
3 Reads

Sexual health and health-related quality of life among women with pulmonary arterial hypertension.

Pulm Circ 2018 Oct-Dec;8(4):2045894018788277

1 Division of Pulmonary, Critical Care, and Sleep Medicine, Rhode Island Hospital, Providence, RI, USA.

Pulmonary arterial hypertension (PAH) is characterized by progressive limitations in physical activity and health-related quality of life (HRQoL). HRQoL deficits may extend beyond the traditional domains of physical activity, psychological health, and emotional wellbeing to sexual health and function. Sexual HRQoL has not been studied in PAH, nor has the impact of PAH therapies themselves on sexual health and intimacy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/2045894018788277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102766PMC
August 2018
14 Reads

[Assessment of insomnia among Tunisian patients with lung cancer].

Rev Mal Respir 2018 Sep 8;35(7):716-722. Epub 2018 Aug 8.

Unité de recherche 12SP06, service de pneumologie allergologie, faculté de médecine de Tunis, université de Tunis El Manar, CHU La Rabta, 1007 Tunis, Tunisie.

Introduction: Sleep disorders are relatively common in oncology. However, they have not been well studied and are often treated insufficiently.

Aim: To assess the prevalence and severity of insomnia in lung cancer patients and evaluate the relationship between insomnia and certain clinical parameters. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.rmr.2017.10.669DOI Listing
September 2018
1 Read

Impact of Poor Sleep on Physical and Mental Health in Older Women.

Sleep Med Clin 2018 Sep;13(3):457-465

Department of Health and Human Physiology, University of Iowa, Iowa City, IA 52242, USA; Department of Epidemiology, University of Iowa, Iowa City, IA 52242, USA.

Many aspects of sleep and circadian rhythms change as people age. Older adults usually experience decrease in sleep duration and efficiency, increase in sleep latency and fragmentation, high prevalence of sleep disorders, and weakened rest-activity rhythms. Research evidence suggests that women are more likely to report aging-related sleep problems. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jsmc.2018.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092035PMC
September 2018
11 Reads

Sleep and Sleep Disorders in the Menopausal Transition.

Sleep Med Clin 2018 Sep;13(3):443-456

Department of Pulmonary Diseases and Clinical Allergology, Sleep Research Centre, University of Turku, Turku, Finland; Department of Obstetrics and Gynecology, Turku University Hospital, University of Turku, Turku, Finland.

The menopausal transition is associated with an increase in insomnia symptoms, especially difficulty staying asleep, which negatively impacts quality of life. Vasomotor symptoms are a key component of sleep disruption. Findings from polysomnographic studies are less consistent in showing disrupted sleep in menopausal transition independent of aging; further prospective studies are needed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jsmc.2018.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092036PMC
September 2018
18 Reads

The Role of Circadian Rhythms in Postpartum Sleep and Mood.

Sleep Med Clin 2018 Sep;13(3):359-374

Department of Psychiatry, Stavanger University Hospital, Gerd Ragna Bloch Thorsens Gate 8, 4011 Stavanger, Norway.

Women often experience sleep disturbances and worsening sleep quality throughout pregnancy and postpartum. Circadian rhythms are closely linked to sleep problems and mood disorders. This systematic review provides a summary of studies of circadian rhythms and associated sleep problems and maternal distress, among postpartum women. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S1556407X183003
Publisher Site
http://dx.doi.org/10.1016/j.jsmc.2018.04.006DOI Listing
September 2018
34 Reads

Sleep-Disordered Breathing in Pregnancy.

Sleep Med Clin 2018 Sep;13(3):349-357

Section of Pulmonary, Critical Care, and Sleep Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA. Electronic address:

Sleep-disordered breathing (SDB) in pregnancy can present as snoring and/or obstructive sleep apnea (OSA), and the prevalence is increasing due to the increase in maternal obesity. Pregnant women often present with fatigue and daytime sleepiness rather than the classic symptoms. Habitual snoring, older age, chronic hypertension, and high prepregnancy body mass index are reliable indicators of increased risk for SDB and should trigger further testing. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jsmc.2018.04.005DOI Listing
September 2018
1 Read

Impact of Shift Work on the Circadian Timing System and Health in Women.

Sleep Med Clin 2018 Sep;13(3):295-306

Department of Psychiatry, Centre for Study and Treatment of Circadian Rhythms, Douglas Mental Health University Institute, McGill University, 6875 LaSalle Boulevard, Montreal, Quebec H4H 1R3, Canada. Electronic address:

Women who do shift work are a sizable part of the workforce. Shift workers experience circadian misalignment due to shifted sleep periods, with potentially far-reaching health consequences, including elevated risk of sleep disturbances, metabolic disorders, and cancer. This review provides an overview of the circadian timing system and presents the sex differences that can be observed in the functioning of this system, which may account for the lower tolerance to shift work for women compared with men. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S1556407X183003
Publisher Site
http://dx.doi.org/10.1016/j.jsmc.2018.04.003DOI Listing
September 2018
6 Reads

Menstrual Cycle Effects on Sleep.

Sleep Med Clin 2018 Sep;13(3):283-294

Department of Family Health Care Nursing, UCSF School of Nursing, University of California, San Francisco, Box 0606, San Francisco, CA 94143, USA.

Subjective and objective sleep changes occur during the menstrual cycle. Poorer sleep quality in the premenstrual phase and menstruation is common in women with premenstrual symptoms or painful menstrual cramps. There is increased sleep spindle activity from follicular to luteal phase, potentially progesterone related. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jsmc.2018.04.002DOI Listing
September 2018
24 Reads

Perinatal Sleep Problems: Causes, Complications, and Management.

Obstet Gynecol Clin North Am 2018 Sep;45(3):483-494

Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, MSC 861, Charleston, SC 29425, USA.

Changes in sleep are ubiquitous in the perinatal period and it is important to be able to determine when these changes are significant enough to indicate sleep deficiency associated with increased risk for poor maternal and infant outcomes. Guidelines for identifying sleep deficiency include insomnia symptoms, excessively shortened sleep duration, and perception of insufficient or nonrestful sleep. Causes and complicating factors related to such sleep problems have been well-documented and are used to tailor behavioral and pharmacologic treatments for women who are pregnant or in the early postpartum period. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ogc.2018.04.003DOI Listing
September 2018
2 Reads

Insomnia and sexual dysfunction associated with severe worsening of the quality of life in sexually active hysterectomized women.

Sleep Sci 2018 Mar-Apr;11(2):99-105

Grupo de Investigación Salud de la Mujer, Facultad de Medicina. Universidad de Cartagena - Cartagena - Bolívar - Colombia.

Hysterectomy is a common gynecologic surgery carried out to remove the pathologic uterus. To establish if sleep disorders and sexual function are associated with deterioration of the quality of life (QoL) in hysterectomized and sexually active women. A cross-sectional study was carried out with inhabitants from two cities of the Colombian Caribbean. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5935/1984-0063.20180019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056062PMC
August 2018
2 Reads

Risk factors for incident heart failure with preserved or reduced ejection fraction, and valvular heart failure, in a community-based cohort.

Open Heart 2018 23;5(2):e000782. Epub 2018 Jul 23.

St. Vincent's Institute of Medical Research, Melbourne, Victoria, Australia.

Background: The lack of effective therapies for heart failure with preserved ejection fraction (HFpEF) reflects an incomplete understanding of its pathogenesis.

Design: We analysed baseline risk factors for incident HFpEF, heart failure with reduced ejection fraction (HFrEF) and valvular heart failure (VHF) in a community-based cohort.

Methods: We recruited 2101 men and 1746 women ≥60 years of age with hypertension, diabetes, ischaemic heart disease (IHD), abnormal heart rhythm, cerebrovascular disease or renal impairment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/openhrt-2018-000782DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059280PMC
July 2018
8 Reads