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Zhonghua Yi Xue Za Zhi 2019 Feb;99(6):411-413

Department of Respiratory and Critical Care Medicine, the First Hospital of China Medical University, Shenyang 110001, China.

Sleep Med 2018 Dec 28;55:124-134. Epub 2018 Dec 28.

Thomas Roth Sleep Disorders & Research Center, Henry Ford Health System, Detroit, MI, USA. Electronic address:

Introduction: Depression increases during menopause, and subclinical depressive symptoms increase risk for major depression. Insomnia is common among postmenopausal women and increases depression-risk in this already-vulnerable population. Recent evidence supports the efficacy of cognitive-behavioral therapy for insomnia (CBTI) to treat menopausal insomnia, but it remains unclear whether treating insomnia also alleviates co-occurring depressive symptoms and depressogenic features. Read More

Psychiatry Res 2019 Jan 31;274:105-111. Epub 2019 Jan 31.

Salisbury VA Health Care System, 1601 Brenner Ave, Salisbury, NC 28144, USA; VA Mid-Atlantic Mental Illness Research, Education, and Clinical Center (MIRECC), 508 Fulton St, Durham, NC 27705, USA; Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, USA. Electronic address:

Around half of Iraq and Afghanistan war veterans with traumatic brain injury (TBI) have co-occurring posttraumatic stress disorder (PTSD). Research on the differences between male and female veterans with co-occurring PTSD/TBI is sparse. This study evaluated behavioral health differences between sexes with these conditions. Read More

Lancet Neurol 2019 Mar 12;18(3):307-318. Epub 2019 Feb 12.

Department of Psychiatry, Neurology, and Epidemiology and Biostatistics, University of California, San Francisco, CA, USA; San Francisco VA Medical Center, San Francisco, CA, USA.

Dysfunction in 24-h circadian rhythms is a common occurrence in ageing adults; however, circadian rhythm disruptions are more severe in people with age-related neurodegenerative diseases, including Alzheimer's disease and related dementias, and Parkinson's disease. Manifestations of circadian rhythm disruptions differ according to the type and severity of neurodegenerative disease and, for some patients, occur before the onset of typical clinical symptoms of neurodegeneration. Evidence from preliminary studies suggest that circadian rhythm disruptions, in addition to being a symptom of neurodegeneration, might also be a potential risk factor for developing Alzheimer's disease and related dementias, and Parkinson's disease, although large, longitudinal studies are needed to confirm this relationship. Read More

Nat Commun 2019 Feb 19;10(1):837. Epub 2019 Feb 19.

Department of Clinical Biochemistry, Molecular Sleep Laboratory, Rigshospitalet, 2600 Glostrup, Denmark.

Narcolepsy Type 1 (NT1) is a neurological sleep disorder, characterized by the loss of hypocretin/orexin signaling in the brain. Genetic, epidemiological and experimental data support the hypothesis that NT1 is a T-cell-mediated autoimmune disease targeting the hypocretin producing neurons. While autoreactive CD4 T cells have been detected in patients, CD8 T cells have only been examined to a minor extent. Read More

BMJ Open 2019 Feb 19;9(2):e025939. Epub 2019 Feb 19.

Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.

Purpose: A prospective cohort study for pregnant women, the Maternity Log study, was designed to construct a time-course high-resolution reference catalogue of bioinformatic data in pregnancy and explore the associations between genomic and environmental factors and the onset of pregnancy complications, such as hypertensive disorders of pregnancy, gestational diabetes mellitus and preterm labour, using continuous lifestyle monitoring combined with multiomics data on the genome, transcriptome, proteome, metabolome and microbiome.

Participants: Pregnant women were recruited at the timing of first routine antenatal visits at Tohoku University Hospital, Sendai, Japan, between September 2015 and November 2016. Of the eligible women who were invited, 65. Read More

BMJ Open 2019 Jan 25;9(1):e023742. Epub 2019 Jan 25.

LIEN, EA4685, University of Western Brittany (UBO), Brest, France.

Introduction: The main symptom of fibromyalgia (FM) is diffuse pain. There is currently no aetiological treatment for FM. However, all pain associations and best practice guidelines strongly advocate the practice of aerobic physical activity to improve the symptoms of FM subjects. Read More

Epileptic Disord 2019 Feb 18. Epub 2019 Feb 18.

Grenoble-Alpes Hospital and University - Neurology Department and GIN INSERM U-1216, Grenoble, France.

This educational review describes the classification of paroxysmal events and a four-dimensional epilepsy classification system. Paroxysmal events are classified as epileptic and non-epileptic paroxysmal events. Non-epileptic events are, in turn, classified as psychogenic and organic paroxysmal events. Read More

Cell Mol Biol (Noisy-le-grand) 2019 Jan 31;65(1):46-51. Epub 2019 Jan 31.

Department of Medical Pharmacology, Faculty of Medicine, Yeditepe University, Istanbul, Turkey.

Obstructive sleep apnea syndrome (OSAS) is a highly prevalent disorder which results in markedly reduced (hypopnea) or absent (apnea) airflow at the nose/mouth. Since vitamin D deficiency has found in an association with some disorders it is thought to be related with OSAS progression. The aim of this study is to investigate the association between VDR, VDBP mutations, vitamin D level and some environmental risk factors with OSAS. Read More

Int J Vitam Nutr Res 2019 Feb 20:1-7. Epub 2019 Feb 20.

3 Department of Neurology, Bahcesehir University, Medical Park Goztepe Hospital, Istanbul, Turkey.

Observational studies performed in homogeneous groups to objectively investigate the cause and effect relationship between vitamin D deficiency and sleep disorders are scarce. In this study, it was aimed to analyze the relationship between the severity of OSAS and vitamin-D levels among the participants whose features affecting serum vit-D levels were minimised. Serum 25-OH vitamin-D levels in 121 OSAS Male patients diagnosed by polysomnography without any systemic disease or vitamin-D supplement that may effect the vitamin-D metabolism were measured. Read More

Health Informatics J 2019 Feb 19:1460458219827349. Epub 2019 Feb 19.

Keio University, Japan.

Getting enough quality sleep plays a vital role in protecting our mental health, physical health, and quality of life. Sleep deprivation can make it difficult to concentrate on daily activities, and lower sleep quality is associated with hypertension, hyperglycemia, and hyperlipidemia. The amount of sleep we get is important, but in recent years, quality sleep has also been deemed significant. Read More

Ann Otol Rhinol Laryngol 2019 Feb 19:3489419831715. Epub 2019 Feb 19.

1 The Sleep Medicine Center, Shengjing Hospital, China Medical University, Shenyang, Liaoning, China.

Objectives:: The treatment of hemangiomas in the hypopharynx and larynx can be challenging and stressful because of the high tumor recurrence rate. The objective of this study was to investigate the therapeutic effect of the combination of intratumor injection of bleomycin and electroresection/electrocautery on the hemangiomas in the hypopharynx and larynx through suspension laryngoscopy.

Methods:: With patients under general anesthesia, the hemangiomas were fully exposed through suspension laryngoscopy. Read More

Perspect Psychiatr Care 2019 Feb 19. Epub 2019 Feb 19.

Unit of Psychiatry, Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macao SAR, China.

Purpose: To examine sleep disturbances in older adults in Macau and Guangzhou, China and their associated factors.

Design And Methods: Four-hundred and thirty seven subjects in Guangzhou and 244 subjects in Macau were interviewed.

Findings: In total, 681 older adults participated in the study, and 27. Read More

Rev Neurol 2018 Nov;67(s01):S1-S21

Hospital La Fe, 46009 Valencia, Espana.

«Apuntes en Neurologia» is an initiative in which prominent national and international leaders, with broad academic recognition, came together to synthesise the most outstanding clinical aspects within their area of interest and to discuss the latest developments in a more accessible language. Understanding the factors that affect the onset and progression of any neurological disease through a review is important to be able to develop strategies to reduce the burden of these diseases. Moreover, knowledge of the clinical aspects is essential to solve the problems of daily clinical practice. Read More

Sleep Breath 2019 Feb 18. Epub 2019 Feb 18.

Department of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, Wilrijkstraat 10, 2650, Edegem, Belgium.

Purpose: The aim of the present study was to assess the efficacy of a sleep position trainer (SPT) in patients with an established diagnosis of positional obstructive sleep apnea and to evaluate the adherence after 1-year follow-up.

Methods: Polysomnography (PSG) was performed at baseline and after 1 year of SPT use. Patients received questionnaires to assess treatment satisfaction and subjective adherence. Read More

Vertex 2018 May;XXIX(139):165-171

Sección de Medicina del sueño. Neurología. Hospital Italiano. Hospital Británico. Buenos Aires.

Kleine-Levin syndrome is an uncommon disorder with recurrent episodes of hypersomnia, and behavioral abnormalities such as binge-eating and hypersexuality. Our aims were to report cases of the Kleine-Levin syndrome diagnosed in Buenos Aires, Argentina and to characterize the clinical presentation of these patients. We evaluated patients with Kleine-Levin syndrome according to the International Classification of Sleep Disorders. Read More

Front Neurol 2019 4;10:20. Epub 2019 Feb 4.

Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, United States.

Loss of organized sleep electrophysiology is a characteristic finding following severe brain injury. The return of structured elements of sleep architecture has been associated with positive prognosis across injury etiologies, suggesting a role for sleep dynamics as biomarkers of wakeful neuronal circuit function. In a continuing study of one minimally conscious state patient studied over the course of ~8½ years, we sought to investigate whether changes in daytime brain activation induced by central thalamic deep brain stimulation (CT-DBS) influenced sleep electrophysiology. Read More

Zh Nevrol Psikhiatr Im S S Korsakova 2019 ;119(1):17-22

Sechenov First Moscow State Medical University, Moscow, Russia.

Aim: To analyze the prevalence of various clinical forms of temporomandibular disorder (TMD) and cervicalgia in episodic (EM) and chronic migraine (CM).

Material And Methods: Ninety patients with CM and 42 patients with EM as defined by the International Classification of Headache Disorders (ICHD)-3 beta were recruited. TMD and sleep bruxism were diagnosed according to the DC/TMD criteria and the International Classification of Sleep Disorders (ICSD-R), respectively. Read More

Psychiatry Res 2019 Feb 6;274:27-29. Epub 2019 Feb 6.

Department of Neurology, Keimyung University School of Medicine, Dongsan Medical Center, School of Medicine, 56 Dalseong-ro, Jung-gu, Daegu 41931, South Korea. Electronic address:

We surveyed patients the next morning after in-laboratory polysomnography (PSG) to compare the first night effect (FNE) and reverse first night effect (RFNE) in different sleep disorders. A questionnaire was given to 852 patients with insomnia (n = 171), restless legs syndrome (n = 186), obstructive sleep apnea (n = 369), simple snoring (n = 54), REM sleep behavior disorder (n = 39), and hypersomnia (n = 33). FNE was seen in 48. Read More

Medicina (B Aires) 2019 ;79 Suppl 1:44-50

Unidad de Pediatría Integral y Sueño, Hospital Quirónsalud, Valencia, Grupo de Sueño de la Sociedad Española de Pediatría Extrahospitalaria y Atención Primaria (SEPEAP), España. E-mail:

Adequate sleep is of critical need for a typical synaptic development and brain maturation, a poor quality sleep can have detrimental effects on children's' cognitive attention, memory, mood regulation, and behavior functions. Great concern has been voiced out regarding the high prevalence of poor sleep in children worldwide, the effects of poor sleep may be even more pronounced in children with neurodevelopmental disorders; these children often have difficulties with falling and staying asleep and with night awakenings, this has a strong association with daytime behavior problems. The purpose of this article is to provide an overview of the state of the science of sleep in children with a neurodevelopmental disorder. Read More

Internet Interv 2019 Apr 27;16:65-75. Epub 2018 Feb 27.

FernFH Distance Learning University of Applied Sciences, Wiener Neustadt, Austria.

Background: The worldwide prevalence of overweight and obesity is at alarming levels. Nearly one in three children in Europe is overweight or obese. Disordered eating and body image concerns are equally widespread and increase risk for more chronic and severe weight-related problems. Read More

Aust N Z J Obstet Gynaecol 2019 Feb 17. Epub 2019 Feb 17.

Department of Respiratory and Sleep Disorders Medicine, The Royal Melbourne Hospital, Melbourne, Victoria, Australia.

Obstructive sleep apnoea (OSA) during pregnancy has been associated with gestational diabetes mellitus, hypertension and low birth weight. Multiple pregnancy is associated with similar adverse perinatal outcomes. Multiple pregnancy rates have risen with increased access to assisted conception; simultaneously, advancing maternal age and weight are also driving a rise in the incidence of OSA in pregnancy. Read More

Cell Metab 2019 Feb 11. Epub 2019 Feb 11.

Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7610001, Israel. Electronic address:

Daily rhythms in animal physiology are driven by endogenous circadian clocks in part through rest-activity and feeding-fasting cycles. Here, we examined principles that govern daily respiration. We monitored oxygen consumption and carbon dioxide release, as well as tissue oxygenation in freely moving animals to specifically dissect the role of circadian clocks and feeding time on daily respiration. Read More

Chronobiol Int 2019 Feb 18:1-7. Epub 2019 Feb 18.

a Education and Psychology , University of Aveiro , Aveiro , Portugal.

It is well established in the literature that morning-type individuals present better health indicators than evening-types. Mindfulness is considered an adaptive self-regulation skill associated with well-being and physical and mental health. However, there is scarce studies that relate chronotype and mindfulness. Read More

Sleep Med 2018 Dec 31;55:69-73. Epub 2018 Dec 31.

Neurology Service, Multidisciplinary Sleep Unit, Hospital Clinic de Barcelona, IDIBAPS, CIBERNED, Barcelona, Spain.

Objective: As Franz Kafka, one of the most important writers of the 20th century, suffered from severe chronic insomnia disorder and inadequate sleep hygiene that impaired his quality of life, we speculated that sleep disorders would be found in his narrative works.

Methods: We read Kafka's complete literary works looking for references to sleep and sleep disorders, excluding insomnia.

Results: In Kafka's works, sleeping well and for a long time was used as an allegory of having a pleasant life. Read More

Sleep Med 2018 Dec 19;55:100-108. Epub 2018 Dec 19.

University of Warwick, Department of Psychology, University Road, CV4 7AL, United Kingdom.

Objectives: The present study explored associations between sleep and children's dual-task performance using cognitive-motor dual tasks (eg, walking and talking). Previous research with older adults indicated correlations between higher gait variability and unfavorable sleep continuity variables. Based on this research, as a first objective, we investigated similar correlations in a sample of children. Read More

Pulm Pharmacol Ther 2019 Feb 13. Epub 2019 Feb 13.

Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Canada.

In the general population, particularly in individuals with asthma, cough is a common symptom, often reported after exertion, although regular exercise may be associated with a reduction in the prevalence of cough. In athletes, exercise-induced cough is also a particularly frequent symptom. The main etiologies of cough in athletes are somewhat similar to non-athletes, including asthma/airway hyperresponsiveness, upper airways disorders such as allergic or non-allergic rhinitis, and exercise-induced laryngeal obstruction, although these conditions are more frequently observed in athletes. Read More

Trials 2019 Feb 15;20(1):134. Epub 2019 Feb 15.

Department of Epidemiology, West Virginia University School of Public Health, HSC N, PO Box 9190, Morgantown, WV, 26506, USA.

Background: Restless legs syndrome (RLS) is a common and burdensome sleep disorder associated with profound impairment of health, well-being, and quality of life. Unfortunately, the medications used for RLS management carry risk of serious side effects, including augmentation of symptoms. Yoga, an ancient mind-body discipline designed to promote physical, emotional, and mental well-being, may offer a viable, low-risk new treatment. Read More

Neuromuscul Disord 2018 Dec 17. Epub 2018 Dec 17.

Erasmus Medical Center, Pompe Center, Rotterdam, The Netherlands.

This multicenter/multinational, open-label, ascending-dose study (NCT01898364) evaluated safety, tolerability, pharmacokinetics, pharmacodynamics, and exploratory efficacy of repeat-dose avalglucosidase alfa (neoGAA), a second-generation, recombinant acid α-glucosidase replacement therapy, in late-onset Pompe disease (LOPD). Patients ≥18 years, alglucosidase alfa naïve (Naïve) or previously receiving alglucosidase alfa for ≥9 months (Switch), with baseline FVC ≥50% predicted and independently ambulatory, received every-other-week avalglucosidase alfa 5, 10, or 20 mg/kg over 24 weeks. 9/10 Naïve and 12/14 Switch patients completed the study. Read More

J Am Acad Child Adolesc Psychiatry 2018 Oct 30. Epub 2018 Oct 30.

Genetic Epidemiology Research Branch, Intramural Research Program, National Institute of Mental Health, Bethesda, MD.

Objective: Recent attention to pervasive sleep deficits in U.S. adolescents has focused on sleep patterns and insomnia, but there are limited data on the prevalence and correlates of hypersomnolence symptoms. Read More

Sleep 2019 Feb 15. Epub 2019 Feb 15.

Department of Mathematics, Université du Québec à Montréal, Québec, Canada.

Study Objectives: Research indicates that sleep efficiency below 80% substantially increases mortality risk in elderly persons. The aim of this study was to identify factors that would best predict poor sleep efficiency in the elderly, and to determine whether associations between these factors and sleep efficiency were similar for men and women and for younger and older elderly persons.

Methods: A total of 2,468 individuals aged 65-96 years (40. Read More

Fed Pract 2018 Apr;35(Suppl 3):S17-S20

is a Neurologist with Noran Neurological Clinic in Minneapolis, Minnesota. is an Associate Professor of Neurology and Program Director of the Sleep Medicine Fellowship at the Mayo Clinic in Jacksonville, Florida. is an Associate Professor of Psychiatry at King Edward Medical University in Lahore, Pakistan. is the Medical Director at the Center for Sleep Medicine at the VA North Texas Health Care System and Associate Professor of Psychiatry and Neurology at the University of Texas Southwestern Medical Center in Dallas.

Researchers developed a restless legs syndrome questionnaire using diagnostic criteria to assess its prevalence among veterans with spinal cord injuries and disorders. Read More

J Neurosci Rural Pract 2019 Jan-Mar;10(1):89-93

Department of Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

Background: Epworth sleepiness scale (ESS) has been used widely in the assessment of daytime sleepiness for research and clinical purposes. Hence, this study was done to translate the ESS in Tamil and to assess the construct validity and reliability of the Tamil version among adolescents in rural Puducherry, South India.

Materials And Methods: Translation of the ESS by native language experts and pilot tested with subsample of adolescents. Read More

Lancet Psychiatry 2019 Feb 11. Epub 2019 Feb 11.

Oxford Autoimmune Neurology Group, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom; Department of Neurology, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. Electronic address:

Background: Early immunotherapy administration improves outcomes in patients with N-methyl-D-aspartate receptor (NMDAR)-antibody encephalitis. As most patients with NMDAR-antibody encephalitis present to psychiatrists, the psychopathology of NMDAR-antibody encephalitis needs to be clearly defined to encourage accurate clinical identification and prompt treatment.

Methods: For this systematic review, we searched PubMed for all studies published in English between Jan 1, 2005, and Oct 7, 2017, to identify individually reported adult patients (≥18 years) who satisfied consensus criteria for definite NMDAR-antibody encephalitis. Read More

Neural Comput 2019 Feb 14:1-20. Epub 2019 Feb 14.

Universitat Politècnica de València, Instituto de Telecomunicaciones y Aplicaciones Multimedia, 46022 Valencia, Spain

Alpha integration methods have been used for integrating stochastic models and fusion in the context of detection (binary classification). Our work proposes separated score integration (SSI), a new method based on alpha integration to perform soft fusion of scores in multiclass classification problems, one of the most common problems in automatic classification. Theoretical derivation is presented to optimize the parameters of this method to achieve the least mean squared error (LMSE) or the minimum probability of error (MPE). Read More

J Clin Med 2019 Feb 5;8(2). Epub 2019 Feb 5.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan.

The association between sleep apnea (SA) and peripheral artery disease (PAD) remains debatable, and there is no clinical tool to predict incident PAD in SA patients. The CHADS₂ score has been found useful in predicting PAD risk. This study was designed to investigate the association between these diseases and the usefulness of CHADS₂ and CHA₂DS₂ASc scores in predicting subsequent PAD in SA patients. Read More

Klin Monbl Augenheilkd 2019 Feb 14;236(2):150-153. Epub 2019 Feb 14.

Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Hamburg-Eppendorf.

The simultaneous occurrence of sleeping disorders and glaucoma is caused by multiple factors and, until today, the underlying mechanisms are not completely understood. There seems to be correlations, either between sleeping disorders in patients with a diagnosed glaucoma and between the onset of a glaucoma in patients with certain sleeping habits, but no precise data has been collected so far. Read More

Sleep 2019 Feb 15. Epub 2019 Feb 15.

Centre for Human Brain Health, University of Birmingham, Birmingham, UK.

Introduction: Functional connectivity (FC) of the human brain's intrinsically connected networks underpins cognitive functioning and disruptions of FC are associated with sleep and neurological disorders. However, there is limited research on the impact of circadian phenotype and time of day on FC.

Study Objectives: The aim of this study was to investigate resting state FC of the default mode network (DMN) in Early and Late circadian phenotypes over a socially constrained day. Read More

Neuroepidemiology 2019 Feb 14;52(3-4):193-204. Epub 2019 Feb 14.

Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Republic of

Background: Restless legs syndrome (RLS) is a common sleep disorder, although it has a low prevalence in Asian populations. However, the reported RLS prevalence in -Korean adults is mostly 4.5-12. Read More

Sleep Med 2018 Dec 14;55:48-55. Epub 2018 Dec 14.

Flinders University, School of Psychology, Adelaide, Australia.

Objectives: Recent evidence indicates that adolescents' motivation to change sleep-wake patterns is low, despite significant impact of adolescent sleep problems on many areas of daytime functioning. The aim of the present study is to evaluate components of adolescents' motivation, and subsequent changes in behaviour.

Methods: Fifty-six adolescents, aged 13-23 (M = 15. Read More

Sleep Med 2018 Dec 14;55:40-47. Epub 2018 Dec 14.

Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address:

Study Objectives: While anxiety rates are alarmingly high in short sleeping insomniacs, the relationship between insomnia and anxiety symptoms has not been extensively studied, especially in comparison to the relationship between insomnia and depressive symptoms. Using residency training as a naturalistic stress exposure, we prospectively assessed the role of sleep disturbance and duration on anxiety-risk in response to stress.

Methods: Web-based survey data from 1336 first-year training physicians (interns) prior to and then quarterly across medical internship. Read More

J Appl Physiol (1985) 2019 Feb 14. Epub 2019 Feb 14.

Department of Allergology, University Central Hospital, Helsinki, Finland, Finland.

Overnight analysis of tidal breathing flow volume loops (TBFV), recorded by impedance pneumography (IP), has been successfully applied in the home monitoring of children with wheezing disorders. However, little is known on how sleep physiology modifies the relationship between TBFV profiles and wheeze. We studied such interactions in wheezing infants. Read More

Medicine (Baltimore) 2019 Feb;98(7):e14509

Baoan Hospital of Traditional Chinese Medicine in Shenzhen, Shenzhen.

Background: Fire-needle moxibustion (FNM) is an ancient method of external therapy that combines acupuncture with moxibustion, and has the property of high temperature resistance. Insomnia is a major public health problem and strongly associated with a high prevalence, impact on daily life, comorbidity with other disorders, and societal costs. The clinical practice demonstrates that FNM has a therapeutic effect on insomnia. Read More

Front Psychol 2019 30;10:50. Epub 2019 Jan 30.

Department of Neurosciences, Biomedicine and Movement, University of Verona, Verona, Italy.

Consciousness is a global activity of the nervous system. Its physiological and pathological mechanisms have been studied in relation to the natural sleep-wake cycle and various forms of normal or morbid unconsciousness, mainly in neurophysiology and clinical neurology. Neuropsychology has been more interested in specific higher brain functions, such as perception and memory and their disorders, rather than in consciousness . Read More

BMC Cancer 2019 Feb 13;19(1):146. Epub 2019 Feb 13.

Management Office for Health Data, China Medical University Hospital, Taichung, Taiwan.

Background: Disrupted sleep rhythms may lead to cancer development. We conducted a population-based cohort study to evaluate the incidence and risk of prostate cancer in patients with sleep disorders (SDs).

Methods: Patients newly diagnosed with SDs between 2000 and 2010 were enrolled from the Taiwan Longitudinal Health Insurance Database. Read More

Aust N Z J Psychiatry 2019 Feb 13:4867419829228. Epub 2019 Feb 13.

1 Neuroscience Graduate Program, McMaster University, Hamilton, ON, Canada.

Objective:: Disruptions in biological rhythms and sleep are a core aspect of mood disorders, with sleep and rhythm changes frequently occurring prior to and during mood episodes. Wrist-worn actigraphs are increasingly utilized to measure ambulatory activity rhythm and sleep patterns.

Methods:: A comprehensive study using subjective and objective measures of sleep and biological rhythms was conducted in 111 participants (40 healthy volunteers [HC], 38 with major depressive disorder [MDD] and 33 with bipolar disorder [BD]). Read More

Physiol Meas 2019 Feb 13. Epub 2019 Feb 13.

Princess Margaret Hospital, Perth, AUSTRALIA.

The purpose of this submission is to provide missing information to complete the conflict of interest statement associated with the article. The statements provided here augment the already provided information rather than replace it. Read More

Expert Opin Pharmacother 2019 Feb 13:1-10. Epub 2019 Feb 13.

a Department of Psychiatry , University of Melbourne, Austin Hospital , Heidelberg , Australia.

Introduction: Agomelatine is an antidepressant with unique pharmacological actions; it is both a melatonin agonist and selective serotonin antagonist. Both actions combined are necessary for antidepressant efficacy. Effects on melatonin receptors enable resynchronisation of disrupted circadian rhythms with beneficial effects on sleep patterns. Read More

Prax Kinderpsychol Kinderpsychiatr 2019 Feb;68(2):128-145

Universität Basel Departement für Sport, Bewegung und Gesundheit Abteilung für Sportwissenschaft Schweiz Departement für Sport, Bewegung und Gesundheit.

Sleep and Psychological Functioning of Children and Adolescents - a Narrative Review Children and adolescents need sufficient and restoring sleep to improve their cognitive, emotional, social and behavioral performance. The present narrative review describes the associations between children's and adolescents' sleep patterns and a broad variety of topics; these topics were chosen at the authors' discretion and does not claim to be exhaustive. After a short introduction, we describe the associations between (adolescent) children's sleep in tight relation to the family functioning. Read More