110,433 results match your criteria Sleep Disorders


A systematic review on the association between obstructive sleep apnea and chronic kidney disease.

Sleep Med Rev 2020 May 18;53:101337. Epub 2020 May 18.

Department of Clinical, Internal, Anesthetic and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy.

This systematic review aims to provide a more comprehensive overview of the association between obstructive sleep apnea (OSA) and chronic kidney disease (CKD). A PubMed search was conducted using the terms "(obstructive sleep disorders OR obstructive sleep apnea OR obstructive sleep apnea syndrome) AND (kidney function OR renal outcome OR chronic kidney disease OR end stage renal disease)". Four hundred seventy four articles were initially retrieved, 227 in the last five years. Read More

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http://dx.doi.org/10.1016/j.smrv.2020.101337DOI Listing

Increased Platelet Aggregation in Children and Adolescents with Sleep Disordered Breathing.

Am J Respir Crit Care Med 2020 Jul 6. Epub 2020 Jul 6.

Women's and Children's Hospital Adelaide, 6053, Respiratory and sleep Medicine, Adelaide, South Australia, Australia.

Objective: Sleep disordered breathing (SDB) is associated with increased vascular resistance in children and adults. Persistent increased vascular resistance damages vascular endothelial cells-a marker of which is increased platelet activation. This study compared whole blood impedance platelet aggregation in children diagnosed clinically as SDB warranting adenotonsillectomy and healthy controls. Read More

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http://dx.doi.org/10.1164/rccm.201911-2229OCDOI Listing

Association of Rapid Eye Movement Sleep With Mortality in Middle-aged and Older Adults.

JAMA Neurol 2020 Jul 6. Epub 2020 Jul 6.

University of California San Francisco, San Francisco.

Importance: Rapid eye movement (REM) sleep has been linked with health outcomes, but little is known about the relationship between REM sleep and mortality.

Objective: To investigate whether REM sleep is associated with greater risk of mortality in 2 independent cohorts and to explore whether another sleep stage could be driving the findings.

Design, Setting, And Participants: This multicenter population-based cross-sectional study used data from the Outcomes of Sleep Disorders in Older Men (MrOS) Sleep Study and Wisconsin Sleep Cohort (WSC). Read More

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http://dx.doi.org/10.1001/jamaneurol.2020.2108DOI Listing

The Resurgence of Medical Ethics During the Coronavirus Disease (COVID)-19 Outbreak.

AIDS Rev 2020 Jun 26;22(3). Epub 2020 Jun 26.

Department of Internal Medicine, UNIR Medical Center and Health Sciences School, Madrid, Spain.

The unprecedented COVID-19 pandemic has risen a number of clinical situations where the principles of the medical act, the singularity of the patient-physician relationship and the need for revitalizing the medical vocation have all become at front line. Original articles, viewpoints, and perspectives addressing these aspects have appeared in major medical journals. Never before but perhaps with AIDS in the eighties, a disease awakened such feelings of commitment in medicine. Read More

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http://dx.doi.org/10.24875/AIDSRev.M20000034DOI Listing

Experience of Treatment and Adherence to Cognitive Behavioral Therapy for Insomnia for Patients with Depression: An Interview Study.

Behav Sleep Med 2020 Jul 5:1-11. Epub 2020 Jul 5.

Department for Affective Disorders, Aarhus University Hospital , Aarhus N, Denmark.

Objective/background: Research supports the efficacy of Cognitive Behavioral Therapy for Insomnia (CBT-I) for patients suffering from depression and insomnia, but little is known about how they experience treatment and adhere to it. Our objective, therefore, was to explore how patients with depression experience treatment components and how their experiences influence adherence to CBT-I as a full-package treatment.

Participants/methods: Twelve patients with depression and comorbid insomnia were interviewed after six sessions of CBT-I, and a conventional qualitative content analysis was conducted. Read More

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http://dx.doi.org/10.1080/15402002.2020.1788033DOI Listing

Are eating disorders associated with bipolar disorder type I? Results of a Lebanese case-control study.

Perspect Psychiatr Care 2020 Jul 5. Epub 2020 Jul 5.

INSPECT-LB: Institut National de Sante Publique, Epidemiologie Clinique et Toxicologie- Liban, Beirut, Lebanon.

Objectives: To assess the association between disordered eating and bipolar disorder (BD).

Methods/design: A case-control study, conducted between April and September 2018, enrolled 50 patients and 50 controls.

Results: Higher eating attitude test scores were significantly associated with the presence of BD. Read More

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http://dx.doi.org/10.1111/ppc.12567DOI Listing

[Sleep and academic performance in university students: a systematic review].

Rev Neurol 2020 Jul;71(2):43-53

Universidad del Estado de Pensilvania , Derry, EEUU.

Introduction: University students tend to suffer from problems of sleep regularity, quantity and quality, which can affect their academic performance. These problems are related to changes typical of the phase of the life cycle in which they find themselves due to maturational, psychosocial development (associated with the processes of individuation and socialisation) and academic factors. The study of the relationship between sleep and academic performance in university students is an area of research of growing interest, which has started to be studied over the last two decades. Read More

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http://dx.doi.org/10.33588/rn.7102.2020015DOI Listing

Inspiratory Muscle Training in Obstructive Sleep Apnea Associating Diabetic Peripheral Neuropathy: A Randomized Control Study.

Biomed Res Int 2020 12;2020:5036585. Epub 2020 Jun 12.

Department of Health and Rehabilitation Sciences, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Alkharj, Saudi Arabia.

Objective: This work is aimed at assessing the effects of inspiratory muscle training on lung functions, inspiratory muscle strength, and aerobic capacity in diabetic peripheral neuropathy (DPN) patients with obstructive sleep apnea (OSA).

Methods: A randomized control study was performed on 55 patients diagnosed with DPN and OSA. They were assigned to the training group (IMT, = 28) and placebo training group (P-IMT, = 27). Read More

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http://dx.doi.org/10.1155/2020/5036585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306097PMC

The Comparison of Emotional Dysregulation and Experiential Avoidance in Patients with Insomnia and Non-Clinical Population.

J Caring Sci 2020 Jun 1;9(2):87-92. Epub 2020 Jun 1.

Department of Psychology, Clinical Research Development Center, Faculty of Medicine, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Given the harmful effects of insomnia and the need for a better understanding of the disorder as well as providing proper care, the present study aimed to compare the emotional dysregulation and experiential avoidance in patients with insomnia and non-clinical individuals. To conduct the present cross-sectional study, two sample groups were selected randomly. The first group consisted of 100 patients with insomnia who visited the Sleep Disorders Research Center at Farabi hospital in Kermanshah, Iran. Read More

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http://dx.doi.org/10.34172/JCS.2020.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322408PMC

A Protocol for Comparing Dry and Wet EEG Electrodes During Sleep.

Front Neurosci 2020 17;14:586. Epub 2020 Jun 17.

Mobile Health Systems Lab, Department of Health Sciences and Technology, Institute of Robotics and Intelligent Systems, ETH Zürich, Zurich, Switzerland.

Background: Sleep is commonly assessed by recording the electroencephalogram (EEG) of the sleeping brain. As sleep assessments in a lab environment are cumbersome for both the participant and researcher, it would be highly desirable to record sleep EEG with a user-friendly and mobile device. Dry electrodes that are reusable, low-cost, and easy to apply would be an essential component of such a device. Read More

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http://dx.doi.org/10.3389/fnins.2020.00586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313551PMC

Shift work sleep disorder and job stress in shift nurses: implications for preventive interventions.

Med Lav 2020 Jun 26;111(3):195-202. Epub 2020 Jun 26.

Department of Mental Health, Local Health Authority, Brindisi, Italy.

Background: A growing literature has revealed a relationship between shift-work, including night-shift, and the disturbance of sleep-wake cycle, leading to insomnia and/or increased daytime sleepiness in shift nurses; recent findings showed an association between shift work sleep disorders and distress, work accidents, decreased job performance and, consequently, lower quality of health service provision and lower standards of care.

Objectives: To analyze across the gender how shift nurses experience shift work sleep disorders and job stress.

Methods: A cross-sectional study was performed following the STROBE Statement. Read More

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http://dx.doi.org/10.23749/mdl.v111i3.9197DOI Listing

Cognitive Dysfunction in Persons with Chronic Spinal Cord Injuries.

Phys Med Rehabil Clin N Am 2020 Aug 3;31(3):345-368. Epub 2020 Jun 3.

Department of Physical Medicine and Rehabilitation, University of Pennsylvania-Perelman School of Medicine, 1800 Lombard Street, Philadelphia, PA 19146, USA. Electronic address:

Cognitive dysfunction (CD) is pervasive in individuals who have chronic spinal cord injuries (SCI). Although classically associated with concomitant traumatic brain injuries, many other causes have been proposed, including premorbid neuropsychological conditions, mood disorders, substance abuse, polypharmacy, chronic pain and fatigue, sleep apnea, autonomic dysregulation, post-intensive care unit syndrome, cortical reorganizations, and neuroinflammation. The consequences of CD are likely widespread, affecting rehabilitation and function. Read More

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http://dx.doi.org/10.1016/j.pmr.2020.04.001DOI Listing

Early morning off in patients with Parkinson's disease: a Chinese nationwide study and a 7-question screening scale.

Transl Neurodegener 2020 Jul 6;9(1):29. Epub 2020 Jul 6.

National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital of Capital Medical University, Beijing, China.

Background: Early morning off (EMO) is a common feature of Parkinson's disease (PD). This study aimed to characterize its clinical features and develop a convenient and pragmatic self-assessment instrument in a Chinese nationwide population.

Methods: This study was conducted on 942 PD patients admitted to 55 clinic centers for movement disorders between June 2018 and May 2019 in China. Read More

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http://dx.doi.org/10.1186/s40035-020-00208-zDOI Listing

[Caregiver burden in patients with Parkinson's disease].

Authors:
Gerhard Ransmayr

Fortschr Neurol Psychiatr 2020 Jul 5. Epub 2020 Jul 5.

Parkinson patients suffering from disease progression become increasingly dependent on personal care, which is mostly provided by female family members. Burden of care correlates with severity of motor impairment, neurocognitive and neuropsychiatric symptoms, behavioral abnormalities, autonomic nervous system disorders, impairment of micturition, sleep, and dependence. Caregiver burden also results from restrictions in time for personal matters, family, leisure and social activities, occupational limits, costs, lack of social support and impairment of sleep, depression, and emotional and other health problems of the carer (such as depression and anxiety). Read More

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http://dx.doi.org/10.1055/a-1120-8567DOI Listing

Prevalence and clinical characteristics of children with medical complexity in Tottori Prefecture, Japan: A population-based longitudinal study.

Brain Dev 2020 Jul 1. Epub 2020 Jul 1.

Division of Child Neurology, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University, Yonago, Japan.

Objectives: To investigate the prevalence and background of children with medical complexity (CMC) and its secular trend in Japan.

Methods: CMC were defined as patients under the age of 20 years requiring medical care and devices. The patients were enrolled using the national health insurance claims data of three hospitals and two rehabilitation centers in Tottori Prefecture. Read More

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http://dx.doi.org/10.1016/j.braindev.2020.06.008DOI Listing

Melatonin daily oral supplementation attenuates inflammation and oxidative stress in testes of men with altered spermatogenesis of unknown aetiology.

Mol Cell Endocrinol 2020 Jul 2:110889. Epub 2020 Jul 2.

Instituto de Biología y Medicina Experimental, CONICET, Ciudad de Buenos Aires, C1428ADN, Argentina; Cátedra de Química, Ciclo Básico Común, Ciudad de Buenos Aires, C1405CAE, Argentina.

We have previously shown an inverse correlation between testicular melatonin concentration and inflammation/oxidative stress-related markers levels in infertile men showing unexplained azoospermia. Here, we evaluated the impact of melatonin oral supplementation (daily 3 mg dose used to treat sleep disorders) in the incidence of local inflammation, oxidative stress, and tubular wall fibrosis development in young and middle-aged infertile adult men. Compared with testes without histological alterations, gonads with morphological abnormalities showed lower melatonin concentration along with increased macrophage numbers, TBARS generation, and expression levels of inflammation-related markers and antioxidant enzymes, as well as tubular wall collagen fibers disorganization and thickening. Read More

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http://dx.doi.org/10.1016/j.mce.2020.110889DOI Listing

Peripheral Vestibular Disorders: Nationwide Evidence From Taiwan.

Laryngoscope 2020 Jul 4. Epub 2020 Jul 4.

School of Health Care Administration, College of Management, Taipei Medical University, Taipei, Taiwan.

Objectives/hypothesis: This study aimed to evaluate the prevalence of peripheral vestibular disorders in an Asian population of predominantly Han Chinese ethnicity.

Study Design: Cross-sectional study.

Methods: Patients with a peripheral vertigo disorder were identified from the Taiwan Health Insurance Research Database, a database of all medical claims of a randomly selected, population-representative sample of 2 million enrollees of Taiwan's National Health Insurance system covering over 99% of Taiwan's citizens. Read More

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http://dx.doi.org/10.1002/lary.28877DOI Listing

[Characteristics of sleep disturbances related to substance use disorders].

Zh Nevrol Psikhiatr Im S S Korsakova 2020 ;120(5):153-159

Bekhterev National Medical Research Center of Psychiatry and Neurology, St. Petersburg, Russia.

Sleep disturbances are frequently observed in patients with substance use disorders during active use as well as in withdrawal period and in remission. However, there is limited information about the association between sleep disturbances and substance use disorders. This review summarizes results of the studies on specific characteristics of sleep disturbances related to alcohol, opioids and psychostimulants (cocaine) use. Read More

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http://dx.doi.org/10.17116/jnevro2020120051153DOI Listing
January 2020

[Impact of sleep disorders on quality of life in epilepsy].

Zh Nevrol Psikhiatr Im S S Korsakova 2020 ;120(5):24-28

Mkhitar Heratsi Yerevan State Medical University, Yerevan, Armenia.

Objective: To study the relationship between sleep disorder symptoms and health-related quality of life (HRQOL) in patients with epilepsy.

Material And Methods: Three groups of participants were included: patients with epilepsy (EG, =151), healthy controls (CG, =130), patients with a confirmed diagnosis of sleep disorder (SDG, =69). HRQOL was assessed with SF-36 containing 8-domains (D1-D8). Read More

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http://dx.doi.org/10.17116/jnevro202012005124DOI Listing
January 2020

[Development of a New Multi-parameter Sleep Quality Evaluation System].

Zhongguo Yi Liao Qi Xie Za Zhi 2020 Mar;44(3):226-230

School of Biomedical Engineering, Shenzhen University, Shenzhen, 518060.

In order to study the effects of sleep-disordered breathing on human physiology and function, and to accurately and objectively evaluate the level of human sleep quality at night, it can help patients with respiratory disorders improve sleep quality. This paper elaborates the development process of a new multi-parameter sleep quality evaluation system from the hardware circuit design, software and algorithm analysis design of the system. The system hardware platform collects the physiological signals of the 11-channel nighttime sleep period, and displays and stores them in real time on the monitoring platform. Read More

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http://dx.doi.org/10.3969/j.issn.1671-7104.2020.03.008DOI Listing

Sleep Disorders and Headache: A Review of Correlation and Mutual Influence.

Pain Ther 2020 Jul 3. Epub 2020 Jul 3.

Department of Neurology, Institute for Postgraduate Education, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.

The review is devoted to the complex relationship between headache and sleep disorders. The shared neuroanatomical structures of the nervous system involved in pain perception and sleep are shown, and mechanisms of comorbidity between headaches and sleep disorders are considered. Various types of headaches in the continuum of the sleep-wake cycle are described. Read More

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http://dx.doi.org/10.1007/s40122-020-00180-6DOI Listing

Measured resting metabolic rate, respiratory quotient, and body composition in patients with narcolepsy: a preliminary report of a case-control study.

Sci Rep 2020 Jul 3;10(1):11024. Epub 2020 Jul 3.

Department of Therapeutic Nutrition, King Khalid University Hospital, King Saud University(KSU)-Medical City, King Saud University (KSU), Riyadh, Kingdom of Saudi Arabia.

This case-control study compared the body composition, resting metabolic rate (RMR), and respiratory quotient (RQ) of narcolepsy patients with those of body mass index (BMI)- gender and age-matched controls. This study included 14 male patients with narcolepsy and 14 matched controls. The narcolepsy patients were subdivided into two subgroups (n = 7/each): those with cataplexy (NT1) and those without cataplexy (NT2). Read More

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http://dx.doi.org/10.1038/s41598-020-67978-4DOI Listing

Sleep in hospitalized patients with chronic obstructive pulmonary disease: an observational study.

J Clin Sleep Med 2020 Jul 6. Epub 2020 Jul 6.

Section of General Internal Medicine, University of Chicago Medical Center, Chicago, Illinois.

Study Objectives: The aim of this study was to compare risk of undiagnosed sleep disorders among medical inpatients with COPD compared to those without COPD.

Methods: In a prospective cohort study, hospitalized medical ward patients without a known sleep disorder were screened for sleep disorders such as obstructive sleep apnea and insomnia while hospitalized using validated questionnaires. Daily sleep duration and efficiency in the hospital were measured via wrist actigraphy. Read More

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http://dx.doi.org/10.5664/jcsm.8646DOI Listing

The influence of placebo administration on the first- night effect in patients with insomnia disorder.

Sleep Med 2020 Mar 12;72:138-143. Epub 2020 Mar 12.

Peking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Peking University, Beijing, China. Electronic address:

Objective: We aimed to investigate the effects of placebo on the first-night effect (FNE) in insomniacs.

Methods: In sum, 36 patients with insomnia disorder who met the DSM-5 criteria were enrolled in this study. Sixteen patients with insomnia disorder were given two days of placebo intervention (placebo-administration group, PL). Read More

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http://dx.doi.org/10.1016/j.sleep.2020.03.002DOI Listing

Adolescent Alcohol Exposure Increases Orexin-A/Hypocretin-1 in the Anterior Hypothalamus.

Alcohol 2020 Jun 30. Epub 2020 Jun 30.

Department of Neuroscience, The Scripps Research Institute, La Jolla CA 92037. Electronic address:

Adolescence is a time of marked changes in sleep, neuromaturation, and alcohol use. While there is substantial evidence that alcohol disrupts sleep and that disrupted sleep may play a role in the development of alcohol use disorders (AUD), there is very little known about the brain mechanisms underlying this phenomenon. The orexin (also known as hypocretin) system is fundamental for a number of homeostatic mechanisms including the initiation and maintenance of wakefulness that may be impacted by adolescent alcohol exposure. Read More

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http://dx.doi.org/10.1016/j.alcohol.2020.06.003DOI Listing

Cognitive Effects of Split and Continuous Sleep Schedules in Adolescents Differ According to Total Sleep Opportunity.

Sleep 2020 Jul 3. Epub 2020 Jul 3.

Centre for Sleep and Cognition, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

Study Objectives: We compared the basic cognitive functions of adolescents undergoing split (nocturnal sleep + daytime nap) and continuous nocturnal sleep schedules when total sleep opportunity was either below or within the recommended range (i.e. 6. Read More

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http://dx.doi.org/10.1093/sleep/zsaa129DOI Listing

Adverse effects of circadian desynchrony on the male reproductive system: an epidemiological and experimental study.

Hum Reprod 2020 Jul 3. Epub 2020 Jul 3.

Key Lab of Medical Protection for Electromagnetic Radiation, Ministry of Education of China, Institute of Toxicology, College of Preventive Medicine, Third Military Medical University (Army Medical University), Chongqing 400038, China.

Study Question: Is circadian desynchrony a risk factor of male reproductive damage in semen parameters and/or reproductive hormones?

Summary Answer: Circadian desynchrony correlates with decrease of sperm count, which was improved when circadian desynchrony was attenuated.

What Is Known Already: Circadian desynchrony caused by work (shift work) and non-work-related reasons is prevalent worldwide and has been found to be associated with decreased female fertility, but whether it harms male reproductive health is unclear.

Study Design, Size, Duration: A hybrid research was conducted. Read More

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http://dx.doi.org/10.1093/humrep/deaa101DOI Listing

The dentist's role in diagnosis and treatment of obstructive sleep apnea syndrome: a literature review.

J Biol Regul Homeost Agents 2020 May-Jun;34(3 Suppl. 1):173-180

Department of Life, Health and Environmental Sciences, University of L'Aquila, Italy.

The purpose of this work was to present a review of the literature concerning obstructive sleep apnea syndrome, and the role of the dentist in this pathology, both to identify elements useful for a good diagnosis and to apply the available therapeutic strategies. In literature there is no unanimous opinion on the treatment of OSAS. The multidisciplinary approach is necessary, creating teams made up of dentists, otolaryngologists and medical experts in sleep disorders, in order to develop a cooperation-based treatment plan for the disease. Read More

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The dentist's role in diagnosis and treatment of obstructive sleep apnea syndrome: a literature review.

J Biol Regul Homeost Agents 2020 May-Jun;34(3 Suppl. 1):173-180

Department of Life, Health and Environmental Sciences, University of L'Aquila, Italy.

The purpose of this work was to present a review of the literature concerning obstructive sleep apnea syndrome, and the role of the dentist in this pathology, both to identify elements useful for a good diagnosis and to apply the available therapeutic strategies. In literature there is no unanimous opinion on the treatment of OSAS. The multidisciplinary approach is necessary, creating teams made up of dentists, otolaryngologists and medical experts in sleep disorders, in order to develop a cooperation-based treatment plan for the disease. Read More

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Evaluating the Feasibility and Acceptability of Internet-Based Cognitive Behavioral Therapy for Insomnia in Rural Women.

Womens Health Rep (New Rochelle) 2020 5;1(1):114-122. Epub 2020 May 5.

Department of Behavioral Science, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.

Insomnia, one of the most common sleep disorders among women in midlife, is associated with multiple negative health outcomes. Rural Appalachian women are disproportionately affected by insufficient sleep, but their barriers to care (, health care shortages, cultural norms) may prevent intervention. This study assessed the feasibility and acceptability of Sleep Healthy Using the Internet (SHUTi) an Internet-based version of cognitive behavioral therapy for insomnia in Appalachian women ages 45+ years. Read More

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http://dx.doi.org/10.1089/whr.2020.0053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325489PMC

Perspective on Melatonin Use for Sleep Problems in Autism and Attention-Deficit Hyperactivity Disorder: A Systematic Review of Randomized Clinical Trials.

Cureus 2020 May 28;12(5):e8335. Epub 2020 May 28.

Psychiatry, Griffin Memorial Hospital, Norman, USA.

Melatonin is a hormone produced by the pineal gland and is available over the counter for treating sleep problems in the pediatric population. We conducted a systematic review of randomized clinical trials (RCTs) on MEDLINE and included six studies that met our inclusion criteria. RCTs were conducted in patients from two to 18 years of age with a diagnostic and statistical manual of mental disorders (DSM)-IV diagnosis of autism spectrum disease (ASD) and/or attention-deficit hyperactivity disorder (ADHD) in both short-term and long-term RCTs ranging from eight-week to 52-week studies. Read More

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http://dx.doi.org/10.7759/cureus.8335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325410PMC

Sleep Quality in Psoriasis Patients and its Relations with Possible Affecting Factors.

Sisli Etfal Hastan Tip Bul 2020 20;54(2):181-187. Epub 2020 May 20.

Department of Neurology, Bakirkoy Prof. Dr. Mazhar Osman Research and Training Hospital for Psychiatry, Istanbul, Turkey.

Objectives: Psoriasis (PS) is a chronic, immune-mediated inflammatory skin disease. PS may lead to significant effects on health-related quality of life (HRQoL) and other outcomes. In the present study, an investigation into sleep quality (SQ), and its possible relations with factors which may affect SQ were aimed. Read More

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http://dx.doi.org/10.14744/SEMB.2018.53189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326668PMC

Neurobiological biomarkers of response to ketamine.

Adv Pharmacol 2020 18;89:195-235. Epub 2020 Jun 18.

Section on the Neurobiology and Treatment of Mood Disorders, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, United States.

As a field, psychiatry is undergoing an exciting paradigm shift toward early identification and intervention that will likely minimize both the burden associated with severe mental illnesses as well as their duration. In this context, the rapid-acting antidepressant ketamine has revolutionized our understanding of antidepressant response and greatly expanded the pharmacologic armamentarium for treatment-resistant depression. Efforts to characterize biomarkers of ketamine response support a growing emphasis on early identification, which would allow clinicians to identify biologically enriched subgroups with treatment-resistant depression who are more likely to benefit from ketamine therapy. Read More

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http://dx.doi.org/10.1016/bs.apha.2020.05.003DOI Listing

[Non-inflammatory muscle pain].

Dtsch Med Wochenschr 2020 Jul 2;145(13):887-894. Epub 2020 Jul 2.

Muscle pain as a common symptom in daily practice frequently occurs as a non-specific accompanying symptom in multiple internal and neurological diseases. Primarily inflammatory or autoimmune muscular diseases are causing muscle pain. However, a number of non-inflammatory causes of pain can also be considered for differential diagnosis. Read More

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http://dx.doi.org/10.1055/a-1068-5210DOI Listing

The effect of baclofen on objective and subjective sleep measures in a model of transient insomnia.

Sleep Med 2020 Apr 4;72:130-134. Epub 2020 Apr 4.

University of Oklahoma Health Sciences Center, Lynn Health Science Institute, Oklahoma City, OK, USA. Electronic address:

Study Objectives: Insomnia is a common medical complaint. Current pharmacologic treatments have modest efficacy and numerous side effects. Baclofen is a gamma-aminobutyric acid (GABA)b receptor agonist used to treat spasticity in various medical conditions. Read More

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http://dx.doi.org/10.1016/j.sleep.2020.03.028DOI Listing

Inflammation in children with neuromuscular disorders and sleep disordered breathing.

Sleep Med 2020 Apr 9;72:118-121. Epub 2020 Apr 9.

Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK.

Introduction: Paediatric obstructive sleep apnoea is associated with systemic inflammation and co-morbidities. We assessed whether sleep disordered breathing (SDB) due to neuromuscular weakness was associated with elevated airway and systemic pro-inflammatory cytokines.

Methods: Consecutive neuromuscular children (age 5-18years) underwent overnight full polysomnography and morning collection of serum and breath condensate, analysed for cytokines (Interleukin-10, Interleukin-6, Interleukin-1β, Tumour Necrosis Factorα, high-sensitivity C-Reactive Protein, Intercellular and Vascular Adhesion Molecules ICAM-1, VCAM-1). Read More

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http://dx.doi.org/10.1016/j.sleep.2020.03.032DOI Listing

Eyelid Disorders in Ophthalmology Practice: Results from a Large International Epidemiological Study in Eleven Countries.

Ophthalmol Ther 2020 Jul 1. Epub 2020 Jul 1.

Kharkiv National Medical University, Kharkiv, Ukraine.

Purpose: Anecdotal evidence suggests that eyelid disorders are common, although estimates of prevalence vary. The current study determines the prevalence of eyelid disorders, meibomian gland dysfunction (MGD) and related diseases (specifically ocular surface disease) in a population of patients presenting for routine ophthalmologic consultations.

Methods: This cross-sectional epidemiologic survey evaluated patients presenting for routine ophthalmic visits. Read More

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http://dx.doi.org/10.1007/s40123-020-00268-4DOI Listing

Personality and Sleep Evaluation of Patients with Tinnitus in Japan.

Psychiatr Q 2020 Jul 1. Epub 2020 Jul 1.

Department of Otolaryngology, Head and Neck Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.

In Japan, there have been no examinations of tinnitus with respect to personality traits, and only a few studies have investigated sleep disorders in tinnitus. Understanding the association between these can aid in selecting and developing effective treatment options for patients with tinnitus. This study aimed to clarify the relationship between tinnitus severity, personality, and sleep disorders, in patients with chronic tinnitus in Japan. Read More

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http://dx.doi.org/10.1007/s11126-020-09794-7DOI Listing

Knowledge and attitude of primary care physicians towards obstructive sleep apnea in the Middle East and North Africa region.

Sleep Breath 2020 Jul 1. Epub 2020 Jul 1.

Department of Family Medicine, American University of Beirut Medical Center, Riad El-Solh, Beirut, 1107 2020, Lebanon.

Background/objectives: Sleep disorders are highly prevalent in primary care. Obstructive sleep apnea (OSA) is one of the most common sleep disorders in the world, and it is estimated that only 10 to 20% of OSA cases are diagnosed. Primary care physicians (PCP) play an important role in screening for OSA. Read More

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http://dx.doi.org/10.1007/s11325-020-02137-7DOI Listing

Physiological changes in sleep that affect fMRI inference.

Curr Opin Behav Sci 2020 Jun 23;33:42-50. Epub 2019 Dec 23.

Advanced Magnetic Resonance Imaging Section, National Institute of Neurological Disorders and Stroke.

fMRI relies on a localized cerebral blood flow (CBF) response to changes in cortical neuronal activity. An underappreciated aspect however is its sensitivity to contributions from autonomic physiology that may affect CBF through changes in vascular resistance and blood pressure. As is reviewed here, this is crucial to consider in fMRI studies of sleep, given the close linkage between the regulation of arousal state and autonomic physiology. Read More

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http://dx.doi.org/10.1016/j.cobeha.2019.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328858PMC

Impact of Mandatory Wake Time on Sleep Timing, Sleep Quality and Rest-Activity Cycle in College and University Students Complaining of a Delayed Sleep Schedule: An Actigraphy Study.

Nat Sci Sleep 2020 25;12:365-375. Epub 2020 Jun 25.

Center for Advanced Research in Sleep Medicine, Sacre-Coeur Hospital, CIUSSS-NIM, Montreal, Quebec, Canada.

Background: Individuals complaining of a delayed sleep schedule are expected to have shorter sleep duration and lower sleep quality when they must comply with morning obligations. The changes in the sleep schedule imposed by morning obligations may in turn decrease the stability and amplitude of their rest-activity cycle. These expectations were only partially supported in previous studies, possibly due to poor differentiation between days with mandatory or free wake times. Read More

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http://dx.doi.org/10.2147/NSS.S251743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323815PMC

The Impact of Autism Spectrum Disorder in Comparison with Other Neuro-Developmental Disorders in Children on the Family: Single Centre Experience.

Indian J Psychol Med 2020 May-Jun;42(3):233-237. Epub 2020 Apr 25.

Developmental Pediatrics unit, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.

Background: Neurodevelopmental disorders (NDD), especially autism spectrum disorder (ASD), have a substantial impact on the family, with a consequent decrease in the quality of life. The current study was undertaken to understand if having ASD contributed to a higher impact on families compared to other NDD and to understand additional factors impacting families of children with either disorder in a low-middle income country (LMIC) setting.

Methods: Impact of ASD and other NDD along with sociodemographic factors was examined, by a retrospective analysis, among 540 children in a tertiary care center in South India. Read More

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http://dx.doi.org/10.4103/IJPSYM.IJPSYM_376_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320731PMC

Social trust predicts sleep disorder at 6 years after the Great East Japan earthquake: data from a prospective cohort study.

BMC Psychol 2020 Jul 1;8(1):69. Epub 2020 Jul 1.

Division of Epidemiology, Department of Health Informatics and Public Health, Tohoku University School of Public Health, Graduate School of Medicine, 2-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan.

Background: The physical and psychological health impacts on victims of the Great East Japan Earthquake (GEJE) have lasted for a long time. Some cross-sectional studies have reported a relationship between social networks and/or social support and mental health among victims. Previous studies were cross-sectional observations at one time point after a disaster, it remains unclear whether the lack of social trust soon after the GEJE predicts long-term mental health outcomes among the victims. Read More

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http://dx.doi.org/10.1186/s40359-020-00436-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329408PMC

A Cross-Sectional Comparison of the Prevalence of Obstructive Sleep Apnea Symptoms in Adults With Down Syndrome in Scotland and Japan.

Am J Intellect Dev Disabil 2020 Jul;125(4):260-273

Kyushu University Hospital, Fukuoka, Japan.

Small studies in Western populations report a high prevalence of obstructive sleep apnea (OSA) in adults with Down syndrome. To date, ethnic differences have not been explored. A questionnaire sent to 2,752 adults with Down syndrome aged ≥16 years in Scotland and Japan (789 valid responses) estimated OSA prevalence based on reported symptoms. Read More

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http://dx.doi.org/10.1352/1944-7558-125.4.260DOI Listing

Chronic toxoplasmosis and sleepiness in obstructive sleep apnea: Is there a link?

PLoS One 2020 1;15(7):e0235463. Epub 2020 Jul 1.

Inserm, CHU Grenoble Alpes, HP2, University Grenoble Alpes, Grenoble, France.

Introduction: Sleepiness is the main clinical expression of obstructive sleep apnea (OSA) syndrome resulting from upper airway collapse. Recent studies have discussed the fact that the presence of T. gondii cysts in the brain and the resulting biochemical and immunological mechanisms could be linked to neurobehavioral disorders. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0235463PLOS

The Epidemiology of Migraine Headache in Arab Countries: A Systematic Review.

ScientificWorldJournal 2020 16;2020:4790254. Epub 2020 Jun 16.

Ministry of Health, Riyadh, Saudi Arabia.

Background: Recurring migraine disorders are a common medical problem, standing among the top causes of disability and sufferings. This study aimed to evaluate epidemiological evidence to report updated estimates on prevalence, risk factors, and associated comorbidities of migraine headache in the Arab countries. . Read More

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http://dx.doi.org/10.1155/2020/4790254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315321PMC

Association Between Irritable Bowel Syndrome and Sleep Disturbance in Adolescents.

Adolesc Health Med Ther 2020 11;11:73-77. Epub 2020 Jun 11.

Department of Pediatrics, Faculty of Medicine, Universitas Sriwijaya and Moh Hoesin Hospital, Palembang, Indonesia.

Introduction: Sleep disorder in adolescents is a problem that is rarely considered by both parents and healthcare professionals. Ignorance of sleep disorders is likely caused by the very rare occurrence of associated sporadic or emergency cases. Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by abdominal pain and changes in the defecation pattern. Read More

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http://dx.doi.org/10.2147/AHMT.S248711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295206PMC