191,888 results match your criteria Sleep Diagnosis and Therapy[Journal]


The first night effect during polysomnography, and patients' estimates of sleep quality.

Psychiatry Res 2019 Feb 6;274:27-29. Epub 2019 Feb 6.

Department of Neurology, Keimyung University School of Medicine, Dongsan Medical Center, School of Medicine, 56 Dalseong-ro, Jung-gu, Daegu 41931, South Korea. Electronic address:

We surveyed patients the next morning after in-laboratory polysomnography (PSG) to compare the first night effect (FNE) and reverse first night effect (RFNE) in different sleep disorders. A questionnaire was given to 852 patients with insomnia (n = 171), restless legs syndrome (n = 186), obstructive sleep apnea (n = 369), simple snoring (n = 54), REM sleep behavior disorder (n = 39), and hypersomnia (n = 33). FNE was seen in 48. Read More

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http://dx.doi.org/10.1016/j.psychres.2019.02.011DOI Listing
February 2019

Brief report: Longitudinal associations between physical activity, sleep disturbance and depressive symptoms in adolescent girls.

J Adolesc 2019 Feb 15;72:37-41. Epub 2019 Feb 15.

University of Tartu, Faculty of Medicine, Institute of Sport Sciences and Physiotherapy, Estonia. Electronic address:

Introduction: Physical activity (PA) and sleep disturbances (SD) are related with depressive symptoms in adults. However, evidence that PA and SD are prospectively associated with depression is mixed. The aim of this study was to examine longitudinal and bidirectional associations between PA, SD and depressive symptoms in adolescent girls. Read More

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http://dx.doi.org/10.1016/j.adolescence.2019.02.003DOI Listing
February 2019

Comparison of three different surgical techniques for designing pharyngeal flaps according to findings of videonasopharyngoscopy and multiplanar videofluoroscopy.

Int J Pediatr Otorhinolaryngol 2019 Feb 11;120:123-129. Epub 2019 Feb 11.

Ian Jackson Craniofacial and Cleft Palate Clinic, Beaumont Hospital, Royal Oak, MI, USA.

Background: Velopharyngeal insufficiency (VPI) occurs when the velopharyngeal sphincter (VPS) is unable to completely seal anatomical closure between the nasal and oral cavities during speech. Palatal repair can restore VPS function but the prevalence of VPI after repair has been reported ranging from 20% to 40%. The combination of flexible videonasopharyngoscopy (FVNP) and multiplanar videofluoroscopy (MPVF) has been reported as the best approach for assessing the VPS mechanism and planning effective surgical procedures aimed to correct VPI. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01655876193008
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http://dx.doi.org/10.1016/j.ijporl.2019.02.022DOI Listing
February 2019
4 Reads

Outcome of drug-induced sleep endoscopy-directed surgery for persistent obstructive sleep apnea after adenotonsillar surgery.

Int J Pediatr Otorhinolaryngol 2019 Feb 6;120:118-122. Epub 2019 Feb 6.

Nursing Service, Hospital Universitari General de Catalunya, Sant Cugat del Vallès, Barcelona, Spain; Sant Ildefons Cornellà Health Centre, Institut Català de la Salut, Spain.

Purpose: Drug-induced sleep endoscopy (DISE) is suitable for evaluating persistent obstructive sleep apnea syndrome (OSAS) after adenotonsillar surgery as a means to guide surgical intervention, yet few studies demonstrate its usefulness in resolving the syndrome. We describe our experience of DISE-directed surgery in children with persistent OSAS by analysing objective and subjective outcomes of this treatment.

Methods: Prospective study of 20 otherwise healthy 2-12 year-old children with OSAS persisting after adenotonsillar surgery. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01655876193006
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http://dx.doi.org/10.1016/j.ijporl.2019.02.004DOI Listing
February 2019
1 Read

Screening for inhalation technique errors with electronic medication monitors.

J Allergy Clin Immunol Pract 2019 Feb 15. Epub 2019 Feb 15.

Propeller Health, San Francisco, California, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2019.02.006DOI Listing
February 2019

Endogenous multidien rhythm of epilepsy in rats.

Exp Neurol 2019 Feb 15. Epub 2019 Feb 15.

Aix Marseille Univ, INSERM, INS, Inst Neurosci Syst, Marseille, France.

Recent trials of chronic EEG in humans showed that epilepsy is a cyclical disorder of the brain with rhythms at multiple time-scales: circadian, multi-day (multidien) or even seasonal. Here, we analyzed chronic EEG data (>30 days) in male epileptic rats and unraveled not only circadian but also, slower, multidien rhythms of interictal epileptiform activity with periodicity of about 2-3 and 5-7 days. Importantly, seizures were not uniformly distributed over time, but rather clustered at preferential phases of these underlying rhythms, delineating critical circadian times and multidien phase of heightened seizure risk. Read More

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http://dx.doi.org/10.1016/j.expneurol.2019.02.006DOI Listing
February 2019

Addressing the Psychological Symptoms of Critical Illness: The Importance of "Negative" Trials in Guiding Next Steps.

JAMA 2019 Feb;321(7):649-650

Division of Pulmonary, Critical Care, and Sleep Medicine, University of Washington, Seattle.

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http://dx.doi.org/10.1001/jama.2019.0072DOI Listing
February 2019

[The sleep in children with neurodevelopmental disorders].

Medicina (B Aires) 2019 ;79 Suppl 1:44-50

Unidad de Pediatría Integral y Sueño, Hospital Quirónsalud, Valencia, Grupo de Sueño de la Sociedad Española de Pediatría Extrahospitalaria y Atención Primaria (SEPEAP), España. E-mail:

Adequate sleep is of critical need for a typical synaptic development and brain maturation, a poor quality sleep can have detrimental effects on children's' cognitive attention, memory, mood regulation, and behavior functions. Great concern has been voiced out regarding the high prevalence of poor sleep in children worldwide, the effects of poor sleep may be even more pronounced in children with neurodevelopmental disorders; these children often have difficulties with falling and staying asleep and with night awakenings, this has a strong association with daytime behavior problems. The purpose of this article is to provide an overview of the state of the science of sleep in children with a neurodevelopmental disorder. Read More

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January 2019

Does drug induced sleep endoscopy-directed surgery improve polysomnography measures in children with Down Syndrome and obstructive sleep apnea?

Acta Otolaryngol 2018 Nov;138(11):1009-1013

c Pediatric Otolaryngology , Seattle Children's Hospital , Seattle , WA , USA.

Background: Children with Down Syndrome (DS) and obstructive sleep apnea (OSA) are difficult to treat, as first line therapies may not lead to significant improvement. Drug-induced sleep endoscopy (DISE) directed surgery may be particularly beneficial for these patients.

Objective: To assess change in polysomnography (PSG) measures of patients with DS who underwent DISE-directed surgery. Read More

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http://dx.doi.org/10.1080/00016489.2018.1504169DOI Listing
November 2018

Treatment of Alzheimer's Disease: Trazodone, Sleep, Serotonin, Norepinephrine, and Future Directions.

J Alzheimers Dis 2019 ;67(3):923-930

War Related Illness and Injury Study Center, VA Palo Alto Health Care System and Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, CA, USA.

In this issue, an article by La et al. provides evidence that trazodone delayed cognitive decline in 25 participants with Alzheimer's disease (AD), mild cognitive impairment, or normal cognition. For participants considered to have AD pathology, trazodone non-users declined at a rate 2. Read More

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http://dx.doi.org/10.3233/JAD-181106DOI Listing
January 2019

Clinical Presentation, Diagnostic Features, and Mortality in Dementia with Lewy Bodies.

J Alzheimers Dis 2019 ;67(3):995-1005

Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK.

Background: Dementia with Lewy bodies (DLB) is the second most common degenerative dementia in older people. However, rates of misdiagnosis are high, and little is known of its natural history and outcomes. Very few previous studies have been able to access routine clinical information for large, unbiased DLB cohorts in order to establish initial presentation, neuropsychological profile, and mortality. Read More

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http://dx.doi.org/10.3233/JAD-180877DOI Listing
January 2019

Rapid improvement of cognitive maps in the awake state.

Hippocampus 2019 Feb 18. Epub 2019 Feb 18.

Memory Lab, Department of Psychology, School of Social Sciences, Heriot-Watt University, Edinburgh, UK.

Post-navigation awake quiescence, relative to task engagement, benefits the accuracy of a new "cognitive map". This effect is hypothesized to reflect awake quiescence, like sleep, being conducive to the consolidation and integration of new spatial memories. Sleep has been shown to improve cognitive map accuracy over time. Read More

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http://dx.doi.org/10.1002/hipo.23081DOI Listing
February 2019

Cautery-assisted palatal stiffening operation for obstructive sleep apnea: A systematic review and meta-analysis.

World J Otorhinolaryngol Head Neck Surg 2019 Mar 25;5(1):49-56. Epub 2018 Sep 25.

Tripler Army Medical Center, Division of Otolaryngology, Sleep Surgery and Sleep Medicine, Tripler AMC, 1 Jarrett White Rd, HI 96859, USA.

Objective: To systematically review outcomes for cautery-assisted palatal stiffening operation (CAPSO) as a treatment for adult obstructive sleep apnea (OSA).

Methods: Five databases (including PubMed/MEDLINE) were searched through July 12, 2017.

Results: Eight studies (307 patients) met criteria. Read More

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http://dx.doi.org/10.1016/j.wjorl.2018.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364515PMC

The outcomes of hypoglossal nerve stimulation in the management of OSA: A systematic review and meta-analysis.

World J Otorhinolaryngol Head Neck Surg 2019 Mar 25;5(1):41-48. Epub 2018 Sep 25.

Department of Otolaryngology - Head and Neck Surgery, Medical University of South Carolina, Charleston, SC, USA.

Objectives: Obstructive sleep apnea (OSA) is a prevalent disease with significant health impacts. While first line therapy is CPAP, long-term compliance is low and device misuse is common, highlighting the need for alternative therapies. Upper airway surgery is one alternative, but substantial side effects hamper efficacy. Read More

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http://dx.doi.org/10.1016/j.wjorl.2018.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364516PMC

Floppy eyelid syndrome in stickler syndrome.

Am J Ophthalmol Case Rep 2019 Jun 31;14:14-15. Epub 2019 Jan 31.

Department of Ophthalmology, Mayo Clinic, 200 First Street, SW, Rochester, MN, 55905, USA.

Purpose: To report the possible connection between Stickler syndrome and floppy eyelid syndrome.

Observations: A 36-year-old man with genetically confirmed Stickler syndrome presented with prominent bilateral eyelid laxity consistent with floppy eyelid syndrome. He had a high-arched palate and reported years of apneic episodes during sleep consistent with obstructive sleep apnea (OSA). Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.01.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365810PMC

Cardiotrophin-1 and leptin as cardiovascular risk markers in male patients with obstructive sleep apnea syndrome.

Arch Med Sci Atheroscler Dis 2018 6;3:e123-e128. Epub 2018 Nov 6.

Clinics of Chest Diseases, Kayseri Education and Research Hospital, Kayseri, Turkey.

Introduction: Elevated cardiotrophin-1 (CT-1) and leptin levels are important risk factors for cardiovascular diseases (CVDs). Obstructive sleep apnea syndrome (OSAS) has also been reported to increase this risk. The aim of this study is to evaluate serum concentrations of CT-1 and leptin in patients with OSAS and whether there is a possible association between CT-1, leptin and OSAS severity. Read More

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http://dx.doi.org/10.5114/amsad.2018.79407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374564PMC
November 2018

Intravenous Alpha-1 Antitrypsin Therapy for Alpha-1 Antitrypsin Deficiency: The Current State of the Evidence.

Chronic Obstr Pulm Dis 2018 Nov 28;6(1):100-114. Epub 2018 Nov 28.

Division of Pulmonary, Critical Care and Sleep Medicine, University of Florida, Gainesville.

Alpha-1 antitrypsin deficiency (AATD) is a largely monogenetic disorder associated with a high risk for the development of chronic obstructive pulmonary disease (COPD) and cirrhosis. Intravenous alpha-1 antitrypsin (AAT) therapy has been available for the treatment of individuals with AATD and COPD since the late 1980s. Initial Food and Drug Administration (FDA) approval was granted based on biochemical efficacy. Read More

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http://dx.doi.org/10.15326/jcopdf.6.1.2017.0185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373587PMC
November 2018

Mortality and Exacerbations by Global Initiative for Chronic Obstructive Lung Disease Groups ABCD: 2011 Versus 2017 in the COPDGene® Cohort.

Chronic Obstr Pulm Dis 2019 Jan 10;6(1):64-73. Epub 2019 Jan 10.

Division of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor.

The Global initiative for chronic Obstructive Lung Disease (GOLD) ABCD groupings were recently modified. The GOLD 2011 guidelines defined increased risk as forced expiratory volume in 1 second (FEV) < 50% predicted or ≥ 2 outpatient or ≥ 1 hospitalized exacerbation in the prior year, whereas the GOLD 2017 guidelines use only exacerbation history. We compared mortality and exacerbation rates in the Genetic Epidemiology of COPD Study cohort (COPDGene) by 2011 (exacerbation history/FEV and dyspnea) versus 2017 (exacerbations and dyspnea) classifications. Read More

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http://dx.doi.org/10.15326/jcopdf.6.1.2018.0130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373581PMC
January 2019

Costs of Medical Care Among Augmentation Therapy Users and Non-Users with Alpha-1 Antitrypsin Deficiency in the United States.

Chronic Obstr Pulm Dis 2018 Nov 8;6(1):6-16. Epub 2018 Nov 8.

Pharmaceutical Health Services Research Department, School of Pharmacy, University of Maryland, Baltimore.

: This study is the first to utilize a large claims database to estimate medical costs of patients with alpha-1 antitrypsin deficiency (AATD) in the United States. Adult AATD patients were identified from the OptumLabs™ Data Warehouse. Insurer and patient out-of-pocket costs were categorized into the following cost buckets, stratified by augmentation therapy use: physician visits (PV), emergency department visits (ED), inpatient stays (IP), augmentation therapy (AUG), other prescription drug costs (RX), and other costs (OTH). Read More

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http://dx.doi.org/10.15326/jcopdf.6.1.2017.0187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373584PMC
November 2018

Should spirometer quality control be treated like other laboratory devices?

ERJ Open Res 2019 Feb 11;5(1). Epub 2019 Feb 11.

Division of Pulmonary, Critical Care, and Sleep Medicine, St Louis University, St Louis, MO, USA.

http://ow.ly/Pqdq30nwAmb. Read More

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http://dx.doi.org/10.1183/23120541.00249-2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368997PMC
February 2019

Healthy Teens @ School: Evaluating and disseminating transdiagnostic preventive interventions for eating disorders and obesity for adolescents in school settings.

Internet Interv 2019 Apr 27;16:65-75. Epub 2018 Feb 27.

FernFH Distance Learning University of Applied Sciences, Wiener Neustadt, Austria.

Background: The worldwide prevalence of overweight and obesity is at alarming levels. Nearly one in three children in Europe is overweight or obese. Disordered eating and body image concerns are equally widespread and increase risk for more chronic and severe weight-related problems. Read More

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http://dx.doi.org/10.1016/j.invent.2018.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364512PMC

An unusual variant of scimitar syndrome predisposing to recurrent pneumonia.

Respir Med Case Rep 2019 23;26:240-243. Epub 2019 Jan 23.

Division of Pulmonary Medicine, Mayo Clinic, Phoenix, AZ, USA.

Scimitar syndrome is a rare constellation of congenital conditions pertaining to partial anomalous pulmonary venous return. Radiographically, these anomalous pulmonary veins can resemble a scimitar, and have heterogeneous clinical presentations. We present an unusual case of scimitar syndrome with associated recurrent pneumonia. Read More

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http://dx.doi.org/10.1016/j.rmcr.2019.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366150PMC
January 2019

Non-Cardiac Chest Pain: A Review of Environmental Exposure-Associated Comorbidities and Biomarkers.

EMJ Gastroenterol 2018 Dec 11;7(1):103-112. Epub 2018 Dec 11.

Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, New York University School of Medicine, New York City, New York, USA.

The prevalence of non-cardiac chest pain (NCCP) ranges from 13-33%. A majority of those presenting with a chief complaint of chest pain are found to have a diagnosis of NCCP. Aerodigestive diseases are a cause of NCCP, and billions of dollars are spent annually on the treatment of NCCP. Read More

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December 2018

Effect of Irritable Bowel Syndrome on Sleep Quality and Quality of Life of Inflammatory Bowel Disease in Clinical Remission.

Int J Prev Med 2019 15;10:10. Epub 2019 Jan 15.

Department of Internal Medicine, Metabolic Diseases Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.

Background: Inflammatory bowel disease (IBD) as a chronic and debilitating disease is affected by sleep disturbance which increases the risk of malignancy. Sleep disturbance is more common in irritable bowel syndrome (IBS) and few reported studies have assessed its role in IBD. We evaluated the effect of IBS on sleep quality and quality of life (QOL) of IBD patients in clinical remission. Read More

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http://dx.doi.org/10.4103/ijpvm.IJPVM_364_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360848PMC
January 2019

Investigating the Effects of Oral Ginseng on the Cancer-Related Fatigue and Quality of Life in Patients with Non-Metastatic Cancer.

Int J Hematol Oncol Stem Cell Res 2018 Oct;12(4):313-317

Health Research Institute, Thalassemia and Hemoglobinopathies Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Cancer affects the physical, psychological, and social aspects of the patients' life. Cancer-related fatigue (CRF) is the most common and severe condition among cancer patients. Ginseng has long been used as an efficient treatment for CRF and improvement of quality of life (QOL). Read More

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October 2018

Primed to Sleep: The Dynamics of Synaptic Plasticity Across Brain States.

Front Syst Neurosci 2019 1;13. Epub 2019 Feb 1.

Department of Biomedical Sciences, Elson S. Floyd College of Medicine, Washington State University Spokane, Spokane, WA, United States.

It is commonly accepted that brain plasticity occurs in wakefulness sleep. However, how these different brain states work in concert to create long-lasting changes in brain circuitry is unclear. Considering that wakefulness and sleep are profoundly different brain states on multiple levels (e. Read More

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http://dx.doi.org/10.3389/fnsys.2019.00002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367653PMC
February 2019

Analysis of the most common causes of blood donor deferral in northern Jeddah: a single-center study.

J Blood Med 2019 23;10:47-51. Epub 2019 Jan 23.

Department of Intensive Care, King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia.

Purpose: We aimed to conduct a retrospective study in order to statistically analyze the commonest causes for blood donor rejection in northern Jeddah, Kingdom of Saudi Arabia according to the American Association of Blood Banks. This will help in developing better strategies to minimize the loss of treasured blood donors.

Subjects And Methods: A sample of 500 rejected donors was randomly selected from a single blood bank between October 2016 to May 2017. Read More

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http://dx.doi.org/10.2147/JBM.S178822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350651PMC
January 2019

Could long-term administration of melatonin to prepubertal children affect timing of puberty? A clinician's perspective.

Nat Sci Sleep 2019 31;11:1-10. Epub 2019 Jan 31.

School of Psychology, University of Ottawa, Ottawa, ON, Canada.

Exogenous melatonin can be used to treat sleep disturbance in adults, children, and adolescents. While its short-term use is considered safe, there are some concerns that long-term use might delay children's sexual maturation, possibly by disrupting the decline in nocturnal melatonin levels that occur at the onset of puberty. This narrative review aimed to summarize some of the current knowledge about the potential effects of exogenous melatonin on puberty. Read More

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http://dx.doi.org/10.2147/NSS.S181365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362935PMC
January 2019

Subacromial impingement syndrome: management challenges.

Orthop Res Rev 2018 23;10:83-91. Epub 2018 Oct 23.

The Reading Shoulder Unit, Berkshire Independent Hospital Coley Park, Swallows Croft, Reading, Berkshire, UK,

The painful shoulder is the most common condition seen in specialist shoulder clinics. It is often associated with lack of range of motion and reduced shoulder function. Lack of sleep and difficulties in performing basic daily life activities are common findings. Read More

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http://dx.doi.org/10.2147/ORR.S157864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376459PMC
October 2018

Continuous positive airway pressure improves nocturnal polyuria in ischemic stroke patients with obstructive sleep apnea.

Clin Interv Aging 2019 31;14:241-247. Epub 2019 Jan 31.

Department of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan,

Objectives: To assess the effect of continuous positive airway pressure (CPAP) on nocturia in ischemic stroke patients with obstructive sleep apnea (OSA).

Methods: This was a prospective and non-randomized controlled study in which ischemic stroke patients with OSA being treated in a rehabilitation ward were enrolled. The participants who tolerated CPAP were classified as the CPAP group, while those who refused or could not tolerate CPAP were classified as the control group. Read More

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http://dx.doi.org/10.2147/CIA.S193448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362916PMC
January 2019

Fatigue in children and adolescents with inflammatory bowel disease.

World J Gastroenterol 2019 Feb;25(5):632-643

Department of Paediatric Gastroenterology, Hepatology and Nutrition, University Medical Center Groningen, Groningen 9713 GZ, The Netherlands.

Aim: To identify factors other than active disease and anemia that contribute to fatigue in pediatric inflammatory bowel disease (IBD).

Methods: We performed an electronic search in Medline and EMBASE from their inception to May 2017 using the search term "fatigue" or the related keywords "physical impairment" and "inflammatory bowel disease" with the filter "child" (age 0-18 years). Cross-sectional and case-control studies were included. Read More

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http://dx.doi.org/10.3748/wjg.v25.i5.632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371006PMC
February 2019

Testing the Role of Narrative and Gain-Loss Framing in Messages to Promote Sleep Hygiene among High School Students.

J Health Commun 2019 Feb 18:1-10. Epub 2019 Feb 18.

b Department of Communication , Cornell University , Ithaca , New York , USA.

Insufficient sleep is common during high school and associated with adverse developmental and health outcomes. School-based health promotion efforts hold promise for improving student sleep health. This study examines two message strategies, short personal narratives and gain versus loss message framing, in shaping intentions to get healthy sleep and intentions to talk about the information received. Read More

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http://dx.doi.org/10.1080/10810730.2019.1581305DOI Listing
February 2019

Heart rate changes associated with rhythmic masticatory muscle activities and limb movements in sleep bruxers: Preliminary findings.

Cranio 2019 Feb 16:1-11. Epub 2019 Feb 16.

a Neurological Institute of Jiangxi Province and Department of Neurology , Jiangxi Provincial People's Hospital , Nanchang , PR China.

Objective: To investigate the relationship of rhythmic masticatory muscle activities (RMMAs) and limb movements (LMs) with heart rate (HR) acceleration.

Methods: The amplitude and duration of HR increases, the time to reach peak HR associated with RMMAs/LMs during sleep, duration of movement events, and their relationships with cortical arousal levels were determined in 9 sleep bruxers and 10 normal controls.

Results: A total of 48. Read More

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http://dx.doi.org/10.1080/08869634.2019.1578032DOI Listing
February 2019

Higher serum levels of systemic inflammatory markers are linked to greater inspiratory muscle dysfunction in copd.

Clin Respir J 2019 Feb 18. Epub 2019 Feb 18.

Department of Physical Therapy, University of Miami Miller School of Medicine, Coral Gables, FL - United States.

Background: COPD is associated with an inflammatory response that becomes more pronounced in acute exacerbations. Considerable attention has recently focused on the value of several inflammatory mediators in predicting worsening of COPD-related symptoms. Whereas respiratory muscle dysfunction is also widely present in this population, little is known about how systemic inflammation relates to inspiratory muscle dysfunction in COPD. Read More

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http://dx.doi.org/10.1111/crj.13006DOI Listing
February 2019

Association between sarcopenia and sleep disorder in older patients with diabetes.

Geriatr Gerontol Int 2019 Feb 17. Epub 2019 Feb 17.

Department of Diabetes and Metabolism, Ise Red Cross Hospital, Ise-shi, Japan.

Aim: In the present study, we aimed to examine the association between sarcopenia and sleep disorder in older patients with diabetes using the Japanese version of SARC-F (SARC-F-J).

Methods: Outpatients with diabetes (aged ≥65 years) at the Ise Red Cross Hospital were included in the present study. We used the Japanese version of the Pittsburgh Sleep Quality Index, which is a self-administered questionnaire, to measure sleep disorder. Read More

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http://dx.doi.org/10.1111/ggi.13627DOI Listing
February 2019

Obstructive sleep apnoea in multiple pregnancy.

Aust N Z J Obstet Gynaecol 2019 Feb 17. Epub 2019 Feb 17.

Department of Respiratory and Sleep Disorders Medicine, The Royal Melbourne Hospital, Melbourne, Victoria, Australia.

Obstructive sleep apnoea (OSA) during pregnancy has been associated with gestational diabetes mellitus, hypertension and low birth weight. Multiple pregnancy is associated with similar adverse perinatal outcomes. Multiple pregnancy rates have risen with increased access to assisted conception; simultaneously, advancing maternal age and weight are also driving a rise in the incidence of OSA in pregnancy. Read More

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http://dx.doi.org/10.1111/ajo.12958DOI Listing
February 2019

[Preliminary clinical application of complete digital workflow of design and manufacturing occlusal splint for sleep bruxism].

Beijing Da Xue Xue Bao Yi Xue Ban 2019 Feb;51(1):105-110

Department of Prosthodontics, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.

Objective: To establish a complete workflow of digital design and manufacturing occlusal splint for sleep bruxism, which can be preliminarily applied in clinical use, thus observe the clinical efficacy.

Methods: Twenty-four patients with sleep bruxism were recruited in the study and randomly divided into two groups by using random number tables. Digital-occlusal-splint (experimental group) treatment plan and traditional-occlusal-splint (control-group) treatment plan were carried out for each group, respectively. Read More

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http://dx.doi.org/10.19723/j.issn.1671-167X.2019.01.019DOI Listing
February 2019

Sleep Quality, Duration, and Associated Sexual Function at Older Age: Findings from the English Longitudinal Study of Ageing.

J Sex Med 2019 Feb 14. Epub 2019 Feb 14.

Department of Behavioural Science and Health, University College London, London, United Kingdom.

Introduction: One factor that may plausibly be associated with sexual dysfunction is sleep disturbance. Like sexual problems, complaints of sleep disturbance increase with age and are commonly reported by older adults.

Aims: To examine associations between sleep quality, duration, and a range of sexual problems in a large, representative sample of older adults. Read More

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http://dx.doi.org/10.1016/j.jsxm.2019.01.005DOI Listing
February 2019
3.151 Impact Factor

Oxygen and Carbon Dioxide Rhythms Are Circadian Clock Controlled and Differentially Directed by Behavioral Signals.

Cell Metab 2019 Feb 11. Epub 2019 Feb 11.

Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7610001, Israel. Electronic address:

Daily rhythms in animal physiology are driven by endogenous circadian clocks in part through rest-activity and feeding-fasting cycles. Here, we examined principles that govern daily respiration. We monitored oxygen consumption and carbon dioxide release, as well as tissue oxygenation in freely moving animals to specifically dissect the role of circadian clocks and feeding time on daily respiration. Read More

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http://dx.doi.org/10.1016/j.cmet.2019.01.007DOI Listing
February 2019

Coordinated Emergence of Hippocampal Replay and Theta Sequences during Post-natal Development.

Curr Biol 2019 Feb 1. Epub 2019 Feb 1.

Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK. Electronic address:

Hippocampal place cells encode an animal's current position in space during exploration [1]. During sleep, hippocampal network activity recapitulates patterns observed during recent experience: place cells with overlapping spatial fields show a greater tendency to co-fire ("reactivation") [2], and temporally ordered and compressed sequences of place cell firing observed during wakefulness are reinstated ("replay") [3-5]. Reactivation and replay may underlie memory consolidation [6-10]. Read More

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http://dx.doi.org/10.1016/j.cub.2019.01.005DOI Listing
February 2019

Sex Moderates Relationships Among School Night Sleep Duration, Social Jetlag, and Depressive Symptoms in Adolescents.

J Biol Rhythms 2019 Feb 18:748730419828102. Epub 2019 Feb 18.

Department of Biobehavioral Health, College of Health and Human Development, Pennsylvania State University, University Park, PA, USA.

Social jetlag, a misalignment between sleep timing on the weekend and during the work week, is associated with depressive symptoms among adults across both sexes. A previous study found that later sleep timing was associated with depressive symptoms in women but not men. To date, however, no research has investigated whether the association between social jetlag and depression varies by sex among adolescents. Read More

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http://journals.sagepub.com/doi/10.1177/0748730419828102
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http://dx.doi.org/10.1177/0748730419828102DOI Listing
February 2019
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Mindfulness and self-compassion along the chronotype: a cross-sectional study.

Chronobiol Int 2019 Feb 18:1-7. Epub 2019 Feb 18.

a Education and Psychology , University of Aveiro , Aveiro , Portugal.

It is well established in the literature that morning-type individuals present better health indicators than evening-types. Mindfulness is considered an adaptive self-regulation skill associated with well-being and physical and mental health. However, there is scarce studies that relate chronotype and mindfulness. Read More

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http://dx.doi.org/10.1080/07420528.2018.1564323DOI Listing
February 2019

Psychomotor Performance Decrements following a Successful Physical Activity Intervention for Insomnia.

Behav Sleep Med 2019 Feb 17:1-11. Epub 2019 Feb 17.

b School of Sport, Exercise and Health Sciences , Loughborough University , Loughborough , UK.

Objectives: Evidence supports the view that reductions in cognitive hyperarousal contribute substantially to improved sleep outcomes following cognitive and behavioral interventions for insomnia disorder. Assuming an inverted-u relationship between arousal and performance, a theoretical possibility, supported by limited empirical data, is that the same mediating processes could negatively impact aspects of psychomotor performance, reducing speed on tests of reaction time.

Participants: Sedentary participants (mean age = 59. Read More

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http://dx.doi.org/10.1080/15402002.2019.1578774DOI Listing
February 2019

Detection of REM sleep behaviour disorder by automated polysomnography analysis.

Clin Neurophysiol 2019 Feb 6;130(4):505-514. Epub 2019 Feb 6.

University of Oxford, Institute of Biomedical Engineering, Dept. Engineering Sciences, Oxford, UK.

Objective: Evidence suggests Rapid-Eye-Movement (REM) Sleep Behaviour Disorder (RBD) is an early predictor of Parkinson's disease. This study proposes a fully-automated framework for RBD detection consisting of automated sleep staging followed by RBD identification.

Methods: Analysis was assessed using a limited polysomnography montage from 53 participants with RBD and 53 age-matched healthy controls. Read More

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http://dx.doi.org/10.1016/j.clinph.2019.01.011DOI Listing
February 2019

Improvement in patient-reported sleep in type 2 diabetes and prediabetes participants receiving a continuous care intervention with nutritional ketosis.

Sleep Med 2019 Jan 3;55:92-99. Epub 2019 Jan 3.

Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA; Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA. Electronic address:

Objective: Sleep disruption is frequently associated with type 2 diabetes (T2D) and hyperglycemia. We recently reported the effectiveness of a continuous care intervention (CCI) emphasizing nutritional ketosis for improving HbA1c, body weight and cardiovascular risk factors in T2D patients. The present study assessed the effect of this CCI approach on sleep quality using a subjective patient-reported sleep questionnaire. Read More

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http://dx.doi.org/10.1016/j.sleep.2018.12.014DOI Listing
January 2019

Impact of acute sleep restriction on cerebral glucose metabolism during recovery non-rapid eye movement sleep among individuals with primary insomnia and good sleeper controls.

Sleep Med 2019 Jan 4;55:81-91. Epub 2019 Jan 4.

Department of Psychiatry, Center for Sleep and Circadian Science, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Background: Restricting time in bed improves insomnia symptoms, but the neural mechanisms for this effect are unknown. Total and partial acute sleep restriction may be useful paradigms for elucidating these effects. We examined the impact of acute sleep restriction on cerebral glucose metabolism during non-rapid eye movement (NREM) sleep in individuals with primary insomnia (n = 17) and good sleep (n = 19). Read More

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http://dx.doi.org/10.1016/j.sleep.2018.12.007DOI Listing
January 2019

Reduced response to gabapentin enacarbil in restless legs syndrome following long-term dopaminergic treatment.

Sleep Med 2018 Dec 26;55:74-80. Epub 2018 Dec 26.

European Sleep Institute, Santiago, Chile. Electronic address:

Objectives: To determine whether long-term treatment with dopaminergic agents (DAs) might dampen the response to a non-dopaminergic agent, such as gabapentin enacarbil.

Methods: We performed a two-week randomized, double-blind, crossover, and placebo-controlled study in a single, referral center in dopamine treatment-naive patients and non-augmented patients continuously treated with dopaminergics for the last five consecutive years. Following washout from any previous CNS-active drugs, patients were randomized into one of two groups for two consecutive two-week treatment periods with gabapentin enacarbil (GBPen) and placebo. Read More

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http://dx.doi.org/10.1016/j.sleep.2018.11.025DOI Listing
December 2018

Sleep and sleep disorders in Franz Kafka's narrative works.

Sleep Med 2018 Dec 31;55:69-73. Epub 2018 Dec 31.

Neurology Service, Multidisciplinary Sleep Unit, Hospital Clinic de Barcelona, IDIBAPS, CIBERNED, Barcelona, Spain.

Objective: As Franz Kafka, one of the most important writers of the 20th century, suffered from severe chronic insomnia disorder and inadequate sleep hygiene that impaired his quality of life, we speculated that sleep disorders would be found in his narrative works.

Methods: We read Kafka's complete literary works looking for references to sleep and sleep disorders, excluding insomnia.

Results: In Kafka's works, sleeping well and for a long time was used as an allegory of having a pleasant life. Read More

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http://dx.doi.org/10.1016/j.sleep.2018.12.015DOI Listing
December 2018

Polysomnographic data in Dementia with Lewy Bodies: correlation with clinical symptoms and comparison with other α-synucleinopathies.

Sleep Med 2018 Dec 18;55:62-68. Epub 2018 Dec 18.

Department of Neurology, Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental, Lisboa, Portugal; CEDOC, Chronic Diseases Research Center, NOVA Medical School, USA.

Introduction: Sleep dysfunction is frequent in Dementia with Lewy Bodies (DLB), but polysomnographic (PSG) data is scarce. Our objectives were to: (1) compare PSG data between DLB patients and age normative values (NV), Parkinson's Disease (PD) and idiopathic REM sleep behavior disorder (iRBD) patients; (2) evaluate the relation between of OSA, Fluctuations and Hypersomnolence and PSG data.

Methods: We selected all consecutive patients with DLB, PD and iRBD that underwent video-PSG during a two year period. Read More

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http://dx.doi.org/10.1016/j.sleep.2018.12.006DOI Listing
December 2018

The association between sleep and dual-task performance in preterm and full-term children: an exploratory study.

Sleep Med 2018 Dec 19;55:100-108. Epub 2018 Dec 19.

University of Warwick, Department of Psychology, University Road, CV4 7AL, United Kingdom.

Objectives: The present study explored associations between sleep and children's dual-task performance using cognitive-motor dual tasks (eg, walking and talking). Previous research with older adults indicated correlations between higher gait variability and unfavorable sleep continuity variables. Based on this research, as a first objective, we investigated similar correlations in a sample of children. Read More

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http://dx.doi.org/10.1016/j.sleep.2018.11.024DOI Listing
December 2018