194,260 results match your criteria Sleep Diagnosis and Therapy[Journal]


Trends and predictors of recurrent acute coronary syndrome hospitalizations and unplanned revascularization after index acute myocardial infarction treated with percutaneous coronary intervention.

Am Heart J 2019 Mar 5;212:134-143. Epub 2019 Mar 5.

Centre of Cardiovascular Research and Education in Therapeutics (CCRE), Monash University, Melbourne, Australia; Department of Cardiovascular Medicine, Alfred Hospital, Melbourne, Australia. Electronic address:

Background: Repeat hospitalizations for recurrent acute coronary syndrome (ACS) or unplanned revascularization after acute myocardial infarction (MI) are common, costly and potentially preventable. We aim to describe 10-year trends and identify independent risk factors of these repeat hospitalizations.

Methods: We analyzed data from 9615 patients from the Melbourne Interventional Group registry (2005-2014) who underwent percutaneous coronary intervention (PCI) for their index MI and survived to discharge. Read More

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http://dx.doi.org/10.1016/j.ahj.2019.02.013DOI Listing

Retinal Vessel Phenotype in Patients with Non-Arteritic Anterior Ischemic Optic Neuropathy.

Am J Ophthalmol 2019 Apr 17. Epub 2019 Apr 17.

Department of ophthalmology, University Hospital of Grenoble-Alpes, France; Grenoble-Alpes University, HP2 Laboratory, INSERM U1042, Grenoble, France; Department of Ophthalmology, University Hospital of Grenoble-Alpes, Grenoble, France. Electronic address:

Purpose: The pathophysiology of non-arteritic AION (N-AION) is not completely understood. Studies of the retinal vasculature phenotype in patients with N-AION could help us to understand vascular abnormalities associated with the disease.

Design: Retrospective case series with matched controls. Read More

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http://dx.doi.org/10.1016/j.ajo.2019.04.007DOI Listing

Early parental positive personality and stress: Longitudinal associations with children's sleep.

Br J Health Psychol 2019 Apr 19. Epub 2019 Apr 19.

Department of Psychology, Arizona State University, Tempe, AZ, USA.

Objectives: The current study examined the influence of early parental stress and positive parent personality during infancy on sleep in middle childhood. Further, the role of positive parent personality as a buffer of the association between parental stress and sleep was considered.

Methods: Participants included 381 twins and their primary caregivers who were recruited from birth records in the United States. Read More

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http://dx.doi.org/10.1111/bjhp.12372DOI Listing

Practical approach to establishing pulmonary rehabilitation for people with non-COPD diagnoses.

Respirology 2019 Apr 19. Epub 2019 Apr 19.

Discipline of Physiotherapy, La Trobe University, Melbourne, VIC, Australia.

Pulmonary rehabilitation is a core aspect in the management of patients with chronic respiratory diseases. This paper describes a practical approach to establishing pulmonary rehabilitation for patients with non-COPD diagnoses using examples from the interstitial lung disease (ILD), pulmonary hypertension (PH), bronchiectasis and lung cancer patient populations. Aspects of pulmonary rehabilitation, including the rationale, patient selection, setting of programmes, patient assessment and training components (both exercise and non-exercise aspects), are discussed for these patient groups. Read More

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http://dx.doi.org/10.1111/resp.13562DOI Listing

Sleep apnoea and immune regulation: The story is only beginning.

Respirology 2019 Apr 19. Epub 2019 Apr 19.

Department of Medicine, University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1111/resp.13565DOI Listing

Overweight in family members of probands with ADHD.

Eur Child Adolesc Psychiatry 2019 Apr 19. Epub 2019 Apr 19.

Karakter Child and Adolescent Psychiatry University Center, Reinier Postlaan 12, 6525 GC, Nijmegen, The Netherlands.

The widely reported association between ADHD and overweight may be attributable to genetic and environmental factors also present in unaffected family members. Therefore, the purpose of this study was to examine the association between ADHD and overweight within families. A cohort was used of families with at least one member with ADHD, recruited as part of the Dutch node of the International Multicenter ADHD Genetics (IMAGE) study, with assessments taking place between 2003 and 2006, 2009 and 2012, and 2013 and 2015. Read More

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http://link.springer.com/10.1007/s00787-019-01331-7
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http://dx.doi.org/10.1007/s00787-019-01331-7DOI Listing
April 2019
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Possible Molecular Mediators Involved and Mechanistic Insight into Fibromyalgia and Associated Co-morbidities.

Neurochem Res 2019 Apr 19. Epub 2019 Apr 19.

Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, Punjab, India.

Fibromyalgia is a chronic complex syndrome of non-articulate origin characterized by musculoskeletal pain, painful tender points, sleep problems and co-morbidities including depression, migraine. The etiopathogenesis of fibromyalgia is complex, variable and remains inconclusive. The etiological factors that have been defined include stress, genetic predisposition and environmental components. Read More

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http://link.springer.com/10.1007/s11064-019-02805-5
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http://dx.doi.org/10.1007/s11064-019-02805-5DOI Listing
April 2019
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The Function(s) of Sleep.

Handb Exp Pharmacol 2019 Apr 20. Epub 2019 Apr 20.

Department of Biology, Stanford University, Stanford, CA, USA.

Sleep is a highly conserved phenomenon in endotherms, and therefore it must serve at least one basic function across this wide range of species. What that function is remains one of the biggest mysteries in neurobiology. By using the word neurobiology, we do not mean to exclude possible non-neural functions of sleep, but it is difficult to imagine why the brain must be taken offline if the basic function of sleep did not involve the nervous system. Read More

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http://link.springer.com/10.1007/164_2018_140
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http://dx.doi.org/10.1007/164_2018_140DOI Listing
April 2019
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Update on narcolepsy.

Authors:
P J Reading

J Neurol 2019 Apr 19. Epub 2019 Apr 19.

Department of Neurology, James Cook University Hospital, Middlesbrough, TS4 3BW, UK.

The last two decades have seen an explosion in our understanding of the clinical nature of narcolepsy and its pathogenesis, fuelling new approaches to potentially effective treatments. It is now recognised that the full narcoleptic syndrome has significant adverse effects on sleep regulation across the full 24-h period and is often associated with clinical features outside the sleep-wake domain. The discovery that most narcoleptic subjects specifically lack a hypothalamic neuropeptide (hypocretin, also called orexin) was a truly original and landmark observation in 1999, greatly furthering our understanding both of the syndrome itself and sleep biology in general. Read More

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http://dx.doi.org/10.1007/s00415-019-09310-3DOI Listing

Adherence to Long-Term Follow-Up of Patients with Life-Threatening, Inhaled Synthetic Cannabinoids-Associated Coagulopathy in Chicago.

Lung 2019 Apr 19. Epub 2019 Apr 19.

Division of Pulmonary, Critical Care, Sleep and Allergy Medicine, Department of Medicine (M/C 719), University of Illinois at Chicago, 840 South Wood Street, Chicago, IL, 60612, USA.

A large-scale outbreak of life-threatening, inhaled synthetic cannabinoids (Spice/K2)-associated coagulopathy with bleeding complications was recently reported in Illinois. The causative agents were brodifacoum, difenacoum, and bromadiolone, potent, long-acting, 4-hydroxycoumarin anticoagulant rodenticides (LAAR) that were mixed with Spice/K2 products procured and then inhaled by the victims. We report on 3 poisoned patients who reside in underserved, socioeconomically disadvantaged neighborhoods of Chicago that were admitted and treated successfully at two inner-city, tertiary care hospitals in Chicago. Read More

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http://dx.doi.org/10.1007/s00408-019-00227-2DOI Listing

Quantitative EEG measures in REM and NREM sleep are associated with AHI and nocturnal hypoxemia in men.

Sleep 2019 Apr 20. Epub 2019 Apr 20.

The Health Observatory, Adelaide Medical School, University of Adelaide, The Queen Elizabeth Hospital Campus, Woodville, South Australia, Australia.

Study Objectives: Quantitative EEG measures of sleep may identify vulnerability to obstructive sleep apnea (OSA) sequelae, however, small clinical studies of sleep microarchitecture in OSA show inconsistent alterations. We examined relationships between quantitative EEG measures during rapid eye movement (REM) and non-REM (NREM) sleep and OSA severity among a large population-based sample of men while accounting for insomnia.

Methods: All-night EEG (F4-M1) recordings from full in-home polysomnography (Embletta X100) in 664 men with no prior OSA diagnosis (age ≥40) were processed following exclusion of artefacts. Read More

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http://dx.doi.org/10.1093/sleep/zsz092DOI Listing

Prevalence and Incidence of Narcolepsy in a U.S. Health Care Claims Database, 2008-2010.

Sleep 2019 Apr 20. Epub 2019 Apr 20.

University of South Florida, College of Public Health, Dept. of Epidemiology and Biostatistics, Tampa, FL.

Study Objectives: To determine the prevalence and incidence of narcolepsy using a large U.S. health care claims database. Read More

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http://dx.doi.org/10.1093/sleep/zsz091DOI Listing

Positive Airway Pressure Therapy Reduces Pulmonary Hypertension in Patients Admitted for Acute Heart Failure with Pulmonary Hypertension and Obstructive Sleep Apnea. The ASAP-HF Pilot Trial.

Sleep 2019 Apr 20. Epub 2019 Apr 20.

Clinic for Cardiology, Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, Bad Oeynhausen, Germany.

Pulmonary hypertension(PH) is extremely common in acute decompensated heart failure (ADHF) patients and predicts increased mortality. Obstructive sleep apnea (OSA) is highly prevalent in CHF patients, may contribute to further elevated pulmonary pressures.

Objectives: This study evaluates the impact of positive airway pressure (PAP) therapy on PH in patients admitted for ADHF with OSA. Read More

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https://academic.oup.com/sleep/advance-article/doi/10.1093/s
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http://dx.doi.org/10.1093/sleep/zsz100DOI Listing
April 2019
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Lifestyle Behavior and Mental Health in Early Adolescence.

Pediatrics 2019 Apr 19. Epub 2019 Apr 19.

Population Health Intervention Research Unit, School of Public Health, Edmonton, University of Alberta, Edmonton, Canada;

Background And Objectives: Mental illnesses affect >15% of Canadian adolescents. New preventive strategies are critically needed. We examined the associations of meeting established recommendations for diet, physical activity, sleep, and sedentary behavior in childhood with mental illness in adolescence. Read More

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http://pediatrics.aappublications.org/lookup/doi/10.1542/ped
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http://dx.doi.org/10.1542/peds.2018-3307DOI Listing
April 2019
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Addressing lung transplant with adults with cystic fibrosis: A qualitative analysis of patients' perspectives and experiences.

J Cyst Fibros 2019 Apr 16. Epub 2019 Apr 16.

Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University of Washington, Seattle, WA, USA.

Referral for lung transplantation is a complex process that typically begins with a discussion in cystic fibrosis (CF) clinic. We performed a secondary analysis of interviews conducted at the University of Washington CF Clinic as part of a study of unmet palliative care needs, June 2015 - January 2016, among adults with moderate-to-severe CF-related lung disease. Content analysis methods were used to identify themes related to discussion of lung transplant in CF clinic. Read More

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http://dx.doi.org/10.1016/j.jcf.2019.04.007DOI Listing

Sleep myths: an expert-led study to identify false beliefs about sleep that impinge upon population sleep health practices.

Sleep Health 2019 Apr 16. Epub 2019 Apr 16.

Center for Healthful Behavior Change, Department of Population Health, NYU Langone Health.

Introduction: False beliefs about sleep can persist despite contradicting scientific evidence, potentially impairing population health. Identifying commonly held false beliefs lacking an evidence base ("myths") can inform efforts to promote population sleep health.

Method: We compiled a list of potential myths using Internet searches of popular press and scientific literature. Read More

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http://dx.doi.org/10.1016/j.sleh.2019.02.002DOI Listing

Efficacy of aromatherapy with Rosa damascena in the improvement of sleep quality of cancer patients: A randomized controlled clinical trial.

Complement Ther Clin Pract 2019 May 1;35:57-61. Epub 2019 Feb 1.

Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; Research Center for Psychiatry and Behavior Sciences, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.ctcp.2019.01.017DOI Listing

Paeoniae Radix-containing herbal medicine for patients with restless legs syndrome: A systematic review and meta-analysis.

Complement Ther Clin Pract 2019 May 20;35:329-341. Epub 2019 Mar 20.

Department of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.

Background And Purpose: Paeoniae Radix has been used for legs discomfort such as restless legs syndrome. The aim of this review is to evaluate efficacy and safety of Paeoniae Radix-containing herbal medicine on restless legs syndrome.

Methods: Literature search was conducted on PubMed, Scopus, CENTRAL, CiNii, KTKP, OASIS, and CNKI for randomized controlled trials that evaluated the effects of Paeoniae Radix-containing herbal medicines on restless legs syndrome. Read More

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http://dx.doi.org/10.1016/j.ctcp.2019.03.015DOI Listing

Comparing the effects of massage and aromatherapy massage with lavender oil on sleep quality of cardiac patients: A randomized controlled trial.

Complement Ther Clin Pract 2019 May 8;35:253-258. Epub 2019 Mar 8.

Social Development and Health Promotion Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran. Electronic address:

Introduction: Sleep disorder is a common problem in cardiac patients. This study aimed to investigate the effect of massage and aromatherapy massage on sleep quality of cardiac patients.

Materials And Methods: in this study, 150 subjects were randomly allocated into 1)massage, 2)aromatherapy massage and 3)control. Read More

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http://dx.doi.org/10.1016/j.ctcp.2019.03.005DOI Listing

Acceptance of apitherapeutic methods in patients consulting general physicians or gynaecologists.

Complement Ther Clin Pract 2019 May 7;35:154-157. Epub 2019 Feb 7.

Department of Hematology and Internal Oncology, University of Jena, Am Klinikum 1, 07747, Jena, Germany.

Background: and purpose: Apitherapists promote the medical use of products from the beehive (bee venom, propolis, pollen, honey, royal jelly, dead bees, apilarnil, wax, wax moths), the use of beehive air or therapeutic sleep on a beehive. However, little is known about how far such treatment options are perceived as acceptable by patients.

Methods: Patients visiting either a family doctor in Kehl or a gynecologist in Weilburg (both in Germany) were asked to rate their knowledge of apitherapy as well as their readiness to use apitherapeutic measures. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17443881183074
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http://dx.doi.org/10.1016/j.ctcp.2019.02.005DOI Listing
May 2019
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A Survey of Work-Related Pain Prevalence Among Construction Workers in Hong Kong: A Case-Control Study.

Int J Environ Res Public Health 2019 Apr 18;16(8). Epub 2019 Apr 18.

Department of Building and Real Estate, The Hong Kong Polytechnic University, Hunghom, Kowloon, Hong Kong.

Construction workers undertake demanding physical work and face high risk of injuries in poor working environments. This case-control study investigated the extent of their musculoskeletal pain incidence at work. A total of 2021 construction workers in different trades were interviewed on-site in a survey from December 2017 to December 2018. Read More

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http://dx.doi.org/10.3390/ijerph16081404DOI Listing

Can Work Engagement Be a Resource for Reducing Workaholism's Undesirable Outcomes? A Multiple Mediating Model Including Moderated Mediation Analysis.

Int J Environ Res Public Health 2019 Apr 18;16(8). Epub 2019 Apr 18.

Department of Psychology, University of Campania Luigi Vanvitelli, 8100 Caserta, Italy.

This study aimed to explore a possible process explaining the relationship between workaholism and sleep disorders, including two mediators: work-family conflict and emotional exhaustion. Moreover, since a possible buffering role of work engagement was recently proposed against the detrimental effects of workaholism, the aim was to examine the moderating role of work engagement in the relationship between workaholism and several outcomes such as work-family conflict, emotional exhaustion, and sleep disorders. Two models were tested using conditional process analysis for testing direct and indirect effects on a sample of 395 employees: (1) a serial multiple mediation model, and (2) the same serial multiple mediation model including the moderating role of work engagement. Read More

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http://dx.doi.org/10.3390/ijerph16081402DOI Listing

Clinical Characteristics of Obstructive Sleep Apnea in Psychiatric Disease.

J Clin Med 2019 Apr 18;8(4). Epub 2019 Apr 18.

Division of Pulmonology, Department of Clinical Therapeutics, National and Kapodistrian University of Athens School of Medicine, Alexandra Hospital, 11528 Athens, Greece.

Patients with serious psychiatric diseases (major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia and psychotic disorder) often complain about sleepiness during the day, fatigue, low energy, concentration problems, and insomnia; unfortunately, many of these symptoms are also frequent in patients with Obstructive Sleep Apnea (OSA). However, existing data about the clinical appearance of OSA in Psychiatric Disease are generally missing. The aim of our study was a detailed and focused evaluation of OSA in Psychiatric Disease, in terms of symptoms, comorbidities, clinical characteristics, daytime respiratory function, and overnight polysomnography data. Read More

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http://dx.doi.org/10.3390/jcm8040534DOI Listing

Intracranial volume versus static and pulsatile intracranial pressure values in children with craniosynostosis.

J Neurosurg Pediatr 2019 Apr 19:1-9. Epub 2019 Apr 19.

1Department of Neurosurgery, Oslo University Hospital-Rikshospitalet, Oslo, Norway; and.

OBJECTIVEReduced intracranial volume (ICV) and raised intracranial pressure (ICP) are assumed to be principal pathophysiological mechanisms in childhood craniosynostosis. This study examined the association between ICV and ICP and whether ICV can be used to estimate the ICP.METHODSThe authors analyzed ICV and ICP measurements from children with craniosynostosis without concurrent hydrocephalus and from age-matched individuals without craniosynostosis who underwent diagnostic ICP measurement. Read More

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http://dx.doi.org/10.3171/2019.2.PEDS18767DOI Listing
April 2019
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Automated detection of sleep apnea using sparse residual entropy features with various dictionaries extracted from heart rate and EDR signals.

Comput Biol Med 2019 Mar 26;108:20-30. Epub 2019 Mar 26.

Department of Electronic & Computer Engineering, Ngee Ann Polytechnic, Singapore; Department of Biomedical Engineering, School of Science and Technology, SIM University, Singapore; Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Sleep is a prominent physiological activity in our daily life. Sleep apnea is the category of sleep disorder during which the breathing of the person diminishes causing the alternation in the upper airway resistance. The electrocardiogram derived respiration (EDR) and heart rate (RR-time-series) signals are normally used for the detection of sleep apnea as these two signals capture cardio-pulmonary activity information. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00104825193008
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http://dx.doi.org/10.1016/j.compbiomed.2019.03.016DOI Listing
March 2019
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What is Chronic Cough? Terminology.

J Allergy Clin Immunol Pract 2019 Apr 16. Epub 2019 Apr 16.

Department of Respiratory and Sleep Medicine, John Hunter Hospital, Newcastle, NSW, Australia; Priority Research Centre for Healthy Lungs, The University of Newcastle, Newcastle, NSW, Australia.

Terminology used to define clinical cough is based on features such as duration, underlying causes and associated characteristics such as whether the cough is 'dry' or 'productive'. Terms such as 'Refractory Chronic Cough', 'Unexplained Chronic Cough' and 'Idiopathic Cough' are commonly used to describe a cough that persists despite extensive investigation and therapeutic trials. The use of these terms, sometimes interchangeably, has led to a degree of confusion and with the emergence of the new clinical and mechanisitic concept associated with cough, 'cough hypersensitivity syndrome', there is a need for some clarity in the nomenclature used to describe this condition. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22132198193038
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http://dx.doi.org/10.1016/j.jaip.2019.04.012DOI Listing
April 2019
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What Are the Characteristics of the Upper Airway in Patients With Craniofacial Microsomia?

J Oral Maxillofac Surg 2019 Mar 26. Epub 2019 Mar 26.

Associate Professor, Dutch Craniofacial Center, Department of Oral and Maxillofacial Surgery, Erasmus University Hospital, Sophia Children's Hospital Rotterdam, Rotterdam, The Netherlands; Craniofacial Unit, Great Ormond Street Hospital, London, UK; Craniofacial Center, Department of Plastic and Oral Surgery, Boston Children's Hospital, Boston, MA.

Purpose: Obstructive sleep apnea (OSA) is a common problem in patients with craniofacial microsomia (CFM); however, the exact pathophysiology in patients with CFM remains unclear. The first aim of this study was to evaluate upper airway volume and morphology in patients with CFM. The second aim was to identify risk factors for the presence of OSA. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02782391193034
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http://dx.doi.org/10.1016/j.joms.2019.03.017DOI Listing
March 2019
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Chronic cough and gastroesophageal reflux in children - CHEST Guideline and Expert Panel Report.

Chest 2019 Apr 16. Epub 2019 Apr 16.

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, UMass Memorial Medical Center, Worcester, MA, USA.

Background: Whether gastroesophageal reflux (GER) or GER disease (GERD) causes chronic cough in children is controversial. Using the PICO format, we undertook 4 systematic reviews. For children with chronic cough (>4-weeks duration) and without underlying lung disease: (1) who do not have gastrointestinal GER symptoms, should empirical treatment for GERD be used? (2) with gastrointestinal GER symptoms, does treatment for GERD resolve the cough? (3) with or without gastrointestinal GER symptoms, what GER-based therapies should be used and for how long? (4) if GERD is suspected as the cause, what investigations and diagnostic criteria best determine GERD as the cause of the cough?

Methods: We used the CHEST Expert Cough Panel's protocol and American College of Chest Physicians (CHEST) methodological guidelines and GRADE framework. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00123692193083
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http://dx.doi.org/10.1016/j.chest.2019.03.035DOI Listing
April 2019
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Intermittent hypoxia impairs uterine artery function in pregnant mice.

J Physiol 2019 Apr 19. Epub 2019 Apr 19.

Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, Canada.

Key Points: Obstructive sleep apnoea (OSA) is a chronic condition characterized by intermittent hypoxia that induces oxidative stress and inflammation leading to cardiovascular disease. Women can develop OSA during late pregnancy, which is associated with adverse maternal and fetal outcomes. However, the effects of OSA throughout pregnancy on fetoplacental outcomes are unknown. Read More

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http://dx.doi.org/10.1113/JP277775DOI Listing

Effects of Sleep Deprivation (SD) on Rats via ERK1/2 Signaling Pathway.

Med Sci Monit 2019 Apr 19;25:2886-2895. Epub 2019 Apr 19.

Department of Neurology, Yantai Yuhuangding Hospital, Yantai, Shandong, China (mainland).

BACKGROUND Sleep deprivation (SD) is common in humans, and sleep loss has a significant influence on health and produces related diseases. Orexin-A has been demonstrated to play a role in physiological processes, including feeding, sleep/wake cycle, and energy metabolism. The aim of this study was to investigate the effect of SD on rats and to define the underlying mechanism. Read More

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https://www.medscimonit.com/abstract/index/idArt/913839
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http://dx.doi.org/10.12659/MSM.913839DOI Listing
April 2019
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An internet delivered cognitive behavioural therapy pain management programme for spinal cord injury pain: A randomised controlled trial.

Eur J Pain 2019 Apr 19. Epub 2019 Apr 19.

UCD, School of Public Health, Physiotherapy and Sports Science, Health Science Centre, University College Dublin, Belfield, Dublin4.

Chronic pain is common after spinal cord injury (SCI) and dedicated SCI cognitive behavioural therapy pain management programmes (CBT-PMPs) have a growing evidence-base to support their uptake clinically. The development of internet-delivered treatment options may overcome barriers to the access and uptake of centre-based programmes. This study examines such an approach on quality of lie (QoL), pain, mood and sleep. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/ejp.1402
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http://dx.doi.org/10.1002/ejp.1402DOI Listing
April 2019
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Associations between fatigue, sleep disturbance and eating style in adults with type 2 diabetes: A correlational study.

J Clin Nurs 2019 Apr 19. Epub 2019 Apr 19.

College of Nursing, University of Illinois at Chicago, Chicago, IL, USA.

Aims And Objectives: To test the hypothesis that fatigue and sleep disturbance account for a significant amount of variation in eating styles among people with type 2 diabetes (T2D).

Background: Healthy eating is an important component of diabetes self-care but remains a major challenge. In people with T2D, symptoms of fatigue and sleep disturbance are pervasive. Read More

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http://dx.doi.org/10.1111/jocn.14883DOI Listing

Work, Stress and Play: Students' perceptions of factors impacting on their studies and wellbeing.

Eur J Dent Educ 2019 Apr 19. Epub 2019 Apr 19.

DCT 1 Special Care Dental Services, Buckinghamshire Priority Dental Service, Eaglestone Health Centre, Standing Way, Milton Keynes, MK6 5AZ.

Introduction: This study gathered information about life outside of the course for undergraduates studying at the School of Dentistry, Cardiff University. The aim was to explore how these external factors to the course may affect an individual's academic performance and well-being.

Materials And Methods: A cross-sectional study design was used. Read More

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http://dx.doi.org/10.1111/eje.12436DOI Listing

Using Movement Sensors to Assess Lying Time in Horses With and Without Angular Limb Deformities.

J Equine Vet Sci 2019 Apr 31;75:55-59. Epub 2019 Jan 31.

Canine and Equine Research Group, University of New England, Armidale, New South Wales, Australia; School of Environmental and Rural Science, University of New England, Armidale, New South Wales, Australia.

Chronic musculoskeletal pathologies are common in horses, however, identifying related effects can be challenging. This study tested the hypothesis that movement sensors and analgesics could be used in combination to confirm the presence of restrictive pathologies by assessing lying time. Four horses presenting a range of angular limb deformities (ALDs) and four nonaffected controls were used. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07370806183071
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http://dx.doi.org/10.1016/j.jevs.2019.01.011DOI Listing
April 2019
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[Identification of mouse organ endogenous peptides by high throughput mass spectrometry].

Sheng Wu Gong Cheng Xue Bao 2019 Apr;35(4):697-706

Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing 102206, China.

Endogenous peptides, in the form of cytokines, growth hormones and hormone peptides, play an important role in human hormones, nerves, cell growth and reproduction. Neuropeptide is a kind of endogenous peptide, which is related to the physiological activities of pain, sleep, emotion, learning and memory. Neuropeptides exist not only in the nerve cells of the brain, but also in other body fluids and organs. Read More

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http://www.cnki.net/kcms/doi/10.13345/j.cjb.180377.html
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http://dx.doi.org/10.13345/j.cjb.180377DOI Listing
April 2019
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Obstructive sleep apnoea in Type 2 diabetes mellitus: increased risk for overweight as well as obese people included in a national primary care database analysis.

Diabet Med 2019 Apr 18. Epub 2019 Apr 18.

Department of Clinical and Experimental Medicine, University of Surrey, Guildford, UK.

Aims: To determine obstructive sleep apnoea prevalence in people with Type 2 or Type 1 diabetes in a national primary care setting, stratified by BMI category, and to explore the relationship between patient characteristics and obstructive sleep apnoea.

Methods: Using the Royal College of General Practitioners Research and Surveillance Centre database, a cross-sectional analysis was conducted. Diabetes type was identified using a seven-step algorithm and was grouped by Type 2 diabetes, Type 1 diabetes and no diabetes. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/dme.13968
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http://dx.doi.org/10.1111/dme.13968DOI Listing
April 2019
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The clinical presentation caused by truncating CHD8 variants.

Clin Genet 2019 Apr 18. Epub 2019 Apr 18.

Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Sciences Centre, United Kingdom.

Variants in the chromodomain helicase DNA-binding protein 8 (CHD8) have been associated with intellectual disability (ID), autism spectrum disorders (ASD) and overgrowth and CHD8 is one of the causative genes for OGID (overgrowth and ID). We investigated 25 individuals with CHD8 protein truncating variants (PTVs), including 10 previously unreported patients and found a male to female ratio of 2.7:1 (19:7) and a pattern of common features: macrocephaly (62. Read More

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http://doi.wiley.com/10.1111/cge.13554
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http://dx.doi.org/10.1111/cge.13554DOI Listing
April 2019
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Plasm YKL-40 Levels Are Associated with Hypertension in Patients with Obstructive Sleep Apnea.

Biomed Res Int 2019 13;2019:5193597. Epub 2019 Mar 13.

Department of Otolaryngology, Beijing AnZhen Hospital, Capital Medical University, Beijing 100029, China.

Background: Obstructive sleep apnea (OSA) is a common disease. It can cause many serious complications. OSA may increase the risk of hypertension. Read More

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http://dx.doi.org/10.1155/2019/5193597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436335PMC

Lingual and Maxillary Labial Frenuloplasty with Myofunctional Therapy as a Treatment for Mouth Breathing and Snoring.

Case Rep Otolaryngol 2019 10;2019:3408053. Epub 2019 Mar 10.

The Breathe Institute, Los Angeles, CA, USA.

Chronic mouth breathing may adversely affect craniofacial development in children and may result in anatomical changes that directly impact the stability and collapsibility of the upper airway during sleep. Mouth breathing is a multifactorial problem that can be attributed to structural, functional, and neurological etiologies, which are not all mutually exclusive. While therapeutic interventions (myofunctional, speech and swallowing, occupational, and craniosacral therapy) may address the functional and behavioral factors that contribute to mouth breathing, progress may sometimes be limited by restrictive lingual and labial frenum that interfere with tongue and lip mobility. Read More

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http://dx.doi.org/10.1155/2019/3408053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437727PMC

Sleep disturbances in HIV-infected patients associated with depression and high risk of obstructive sleep apnea.

SAGE Open Med 2019 8;7:2050312119842268. Epub 2019 Apr 8.

Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Objective: To evaluate sleep disturbances in a diverse, contemporary HIV-positive patient cohort and to identify demographic, clinical, and immune correlates.

Methods: A convenience sample of 176 patients from a racially and ethnically diverse HIV-positive patient cohort in an urban population. This was a cross-sectional, epidemiologic study. Read More

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http://dx.doi.org/10.1177/2050312119842268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454647PMC
April 2019
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Acute Social Defeat Stress Increases Sleep in Mice.

Front Neurosci 2019 3;13:322. Epub 2019 Apr 3.

International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Tsukuba, Japan.

Social conflict is a major source of stress in humans. Animals also experience social conflicts and cope with them by stress responses that facilitate arousal and activate sympathetic and neuroendocrine systems. The effect of acute social defeat (SoD) stress on the sleep/wake behavior of mice has been reported in several models based on a resident-intruder paradigm. Read More

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http://dx.doi.org/10.3389/fnins.2019.00322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456680PMC
April 2019
2 Reads

The Spatiotemporal Pattern of the Human Electroencephalogram at Sleep Onset After a Period of Prolonged Wakefulness.

Front Neurosci 2019 3;13:312. Epub 2019 Apr 3.

Department of Psychology, Sapienza University of Rome, Rome, Italy.

During the sleep onset (SO) process, the human electroencephalogram (EEG) is characterized by an orchestrated pattern of spatiotemporal changes. Sleep deprivation (SD) strongly affects both wake and sleep EEG, but a description of the topographical EEG power spectra and oscillatory activity during the wake-sleep transition after a period of prolonged wakefulness is still missing. The increased homeostatic sleep pressure should induce an earlier onset of sleep-related EEG oscillations. Read More

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http://dx.doi.org/10.3389/fnins.2019.00312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456684PMC

Clinical Characteristics of Essential Tremor in South India: A Hospital-Based Cohort Study.

J Neurosci Rural Pract 2019 Apr-Jun;10(2):245-249

Department of Neurology, Princess Esra Hospital, Deccan College of Medical Science, Hyderabad, Telangana, India.

Introduction: Essential tremor (ET) is the most common adult movement disorder. Classic ET is characterized by action tremor of hands (95% cases), and tremor involving other regions is less common. Recent studies have revealed a few patients exhibiting nontremor features that include cognitive disorders, tandem gait abnormality, mood fluctuations, olfactory abnormality, hearing impairment, and sleep disorders. Read More

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http://dx.doi.org/10.4103/jnrp.jnrp_348_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454942PMC

Impact of Etiology on Efficacy of Oral Triclofos in Recording Pediatric Electroencephalography: A Tertiary Care Center Study.

J Neurosci Rural Pract 2019 Apr-Jun;10(2):234-237

Department of Neurology, Niloufer Children's Hospital, Hyderabad, Telangana, India.

Background And Objectives: Oral triclofos is a frequently used sedative in pediatric age to record sleep Electroencephalography (EEG). This study is aimed to assess efficacy, safety profile, need for second dose, and rescheduling of oral triclofos in relation to etiology.

Materials And Methods: This is a retrospective study done enrolling all children aged 6 months to 5 years referred for EEG over 1 year. Read More

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http://dx.doi.org/10.4103/jnrp.jnrp_280_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454965PMC

Categories of Wistar Rats Based on Anxiety Traits: A Study Using Factor and Cluster Method.

Ann Neurosci 2018 Dec 15;25(4):234-240. Epub 2018 Aug 15.

Division of Sleep Research, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.

Background: Outcomes of neurobehavioral studies are invariably affected by the variations in the anxiety traits of animals in the same species. Identifying those traits and categorizing them accordingly would improve the reproducibility of results, and reduce the variation in the results from different laboratories.

Purpose: The present study was done to identify the possible groups among the normal population of outbred adult male Wistar rats. Read More

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http://dx.doi.org/10.1159/000492268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470331PMC
December 2018

Assessment of predisposing factors in myofascial pain syndrome and the analgesic effect of trigger point injections - A primary therapeutic interventional clinical trial.

Indian J Anaesth 2019 Apr;63(4):300-303

Department of Anaesthesiology, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth University, Pondicherry, India.

Background And Aims: Myofascial pain syndrome (MPS) is a common cause of chronic musculoskeletal pain, characterised by myofascial trigger points (TPs). TP injection is an established technique for management of MPS. In this study, we analysed the efficacy of myofascial TP injection of lignocaine and the influencing biomechanical factors on MPS. Read More

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http://dx.doi.org/10.4103/ija.IJA_6_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460974PMC
April 2019
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Quantifying the Magnitude of Pharyngeal Obstruction During Sleep Using Airflow Shape.

Eur Respir J 2019 Apr 18. Epub 2019 Apr 18.

Division of Sleep and Circadian Disorders, Department of Medicine, Brigham & Women's Hospital & Harvard Medical School, Boston, MA, USA.

Rationale: Non-invasive quantification of the severity of pharyngeal airflow obstruction would enable recognition of obstructive central manifestation of sleep apnoea, and identification of symptomatic individuals with severe airflow obstruction despite a low apnoea-hypopnoea index (AHI).

Objectives: Here we provide a novel method that uses simple airflow--time ("shape") features from individual breaths on an overnight sleep study to automatically and non-invasively quantify the of airflow obstruction without oesophageal catheterisation.

Methods: 41 individuals with suspected/diagnosed obstructive sleep apnoea (AHI range=0-91 events·hr) underwent overnight polysomnography with gold-standard measures of airflow (oronasal pneumotach, ) and ventilatory drive (calibrated intraoesophageal diaphragm EMG, ). Read More

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http://erj.ersjournals.com/lookup/doi/10.1183/13993003.02262
Publisher Site
http://dx.doi.org/10.1183/13993003.02262-2018DOI Listing
April 2019
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Predicting respiratory failure in amyotrophic lateral sclerosis: recruiting a few good pulmonologists.

Authors:
Noah Lechtzin

Eur Respir J 2019 Apr 18;53(4). Epub 2019 Apr 18.

Dept of Medicine, Division of Pulmonary, Critical Care and Sleep, Johns Hopkins University School of Medicine, Baltimore, MD, USA

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http://erj.ersjournals.com/lookup/doi/10.1183/13993003.00360
Publisher Site
http://dx.doi.org/10.1183/13993003.00360-2019DOI Listing
April 2019
1 Read