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Zhonghua Yi Xue Za Zhi 2019 Feb;99(6):416-418

Wuxi Branch of Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Wuxi 214000, China.

Zhonghua Yi Xue Za Zhi 2019 Feb;99(6):414-415

The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou 510120, China.

Zhonghua Yi Xue Za Zhi 2019 Feb;99(6):411-413

Department of Respiratory and Critical Care Medicine, the First Hospital of China Medical University, Shenyang 110001, China.

Zhonghua Yi Xue Za Zhi 2019 Feb;99(6):407-410

Department of Respiratory and Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin 300052, China.

Zhonghua Yi Xue Za Zhi 2019 Feb;99(6):401-403

Department of Respiratory and Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin 300052, China.

Annu Rev Clin Psychol 2019 Feb 20. Epub 2019 Feb 20.

Department of Psychiatry, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215; email:

There is overwhelming evidence that sleep is crucial for memory consolidation. Patients with schizophrenia and their unaffected relatives have a specific deficit in sleep spindles, a defining oscillation of non-rapid eye movement (NREM) Stage 2 sleep that, in coordination with other NREM oscillations, mediate memory consolidation. In schizophrenia, the spindle deficit correlates with impaired sleep-dependent memory consolidation, positive symptoms, and abnormal thalamocortical connectivity. Read More

Pediatr Blood Cancer 2019 Feb 20:e27676. Epub 2019 Feb 20.

Division of Pediatric Hematology/Oncology, The Hospital for Sick Children, University of Toronto, Toronto, Canada.

Background: Melatonin is a natural health product used for sleep disturbances. In preliminary studies of adults with advanced cancer, 20 mg of melatonin daily was associated with reduction in anorexia and weight loss-symptoms that also impact pediatric oncology patients. High doses of melatonin have not been studied in pediatrics. Read More

J Pers Disord 2019 Feb 20:1-16. Epub 2019 Feb 20.

University of Georgia, Athens, Georgia.

Clinical theory is skeptical of individuals' ability to recognize the presence, severity, and impact of clinical symptoms and pathological traits (Oltmanns & Powers, 2012); however, empirical work has found moderate self-other convergence for reports of pathological traits and for Antagonism-related personality disorder (PD) constructs (i.e., psychopathy, narcissism, and Machiavellianism), which are characterized by low insight. Read More

J Altern Complement Med 2019 Feb 20. Epub 2019 Feb 20.

1 Earl E. Bakken Center for Spirituality & Healing, The University of Minnesota, Minneapolis, MN.

Objectives: CaringBridge (CB) is a web-based social network where people share information, enlist support, and access resources following a difficult diagnosis; it can also be used to disseminate supportive self-care tools, such as a gratitude practice, for its users. Gratitude practices are shown to reduce stress and fear, improve sleep, and increase positive emotions and overall well-being. The purpose of this article was to report the findings of a brief gratitude intervention delivered to CB users. Read More

JMIR Ment Health 2019 Feb 20;6(2):e12255. Epub 2019 Feb 20.

Westat, Inc, Lebanon, NH, United States.

Background: Mental health recovery refers to an individual's experience of gaining a sense of personal control, striving towards one's life goals, and meeting one's needs. Although people with serious mental illness own and use electronic devices for general purposes, knowledge of their current use and interest in future use for supporting mental health recovery remains limited.

Objective: This study aimed to identify smartphone, tablet, and computer apps that mental health service recipients use and want to use to support their recovery. Read More

Sleep Med 2018 Dec 28;55:124-134. Epub 2018 Dec 28.

Thomas Roth Sleep Disorders & Research Center, Henry Ford Health System, Detroit, MI, USA. Electronic address:

Introduction: Depression increases during menopause, and subclinical depressive symptoms increase risk for major depression. Insomnia is common among postmenopausal women and increases depression-risk in this already-vulnerable population. Recent evidence supports the efficacy of cognitive-behavioral therapy for insomnia (CBTI) to treat menopausal insomnia, but it remains unclear whether treating insomnia also alleviates co-occurring depressive symptoms and depressogenic features. Read More

Sleep Med 2018 Dec 30;55:115-123. Epub 2018 Dec 30.

SleepMed, Inc. Columbia, SC, USA; The University of South Carolina Medical School, Columbia, SC, USA; Bogan Sleep Consultants, LLC, Columbia, SC, USA.

Objective: The purpose of this study was to enhance our understanding of clinical trends in sleep and rapid eye movement (REM) propensity on the multiple sleep latency test (MSLT). Demographic variables of interest included early childhood/advanced age, gender, race, and REM-suppressant use.

Methods: Nocturnal sleep studies and 5-nap MSLTs were retrieved from a large repository of deidentified studies from various US sleep clinics between 2007 and 2015. Read More

Drug Alcohol Depend 2019 Feb 13;197:95-101. Epub 2019 Feb 13.

Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology - NTNU, Trondheim, Norway; Department of Clinical Pharmacology, St. Olav University Hospital, Trondheim, Norway.

Background: In a pilot study, intranasal oxytocin was demonstrated to reduce the benzodiazepine dose needed to relieve withdrawal symptoms during alcohol detoxification. The aim of the present study was to compare the effect of oxytocin and placebo during a three-day period of alcohol detoxification at an addiction treatment center in Norway.

Methods: Randomized, double-blind, placebo-controlled trial with 40 patients fulfilling criteria for ICD-10 diagnosis of alcohol dependence (F10. Read More

Biomed Pharmacother 2019 Feb 18;112:108580. Epub 2019 Feb 18.

Department of Respiratory, Affiliated Wuxi Fifth People's Hospital of Jiangnan University, Wuxi, 214016, China. Electronic address:

Obstructive sleep apnea (OSA) and high salt content in modern diet has been particularly implicated in systemic hypertension, leading to increased morbidity and mortality. Gut dysbiosis, associated with increased risk of systemic immunological imbalance, plays a causal role in the development of cardiovascular diseases. Here, we investigated the effect of Lactobacillus rhamnosus GG strain (LGG) on the development of hypertension induced by OSA and high salt diet. Read More

Psychiatry Res 2019 Jan 31;274:105-111. Epub 2019 Jan 31.

Salisbury VA Health Care System, 1601 Brenner Ave, Salisbury, NC 28144, USA; VA Mid-Atlantic Mental Illness Research, Education, and Clinical Center (MIRECC), 508 Fulton St, Durham, NC 27705, USA; Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, USA. Electronic address:

Around half of Iraq and Afghanistan war veterans with traumatic brain injury (TBI) have co-occurring posttraumatic stress disorder (PTSD). Research on the differences between male and female veterans with co-occurring PTSD/TBI is sparse. This study evaluated behavioral health differences between sexes with these conditions. Read More

Crit Care Clin 2019 Apr 30;35(2):329-340. Epub 2019 Jan 30.

Department of Anesthesiology, Division of Anesthesiology Critical Care Medicine, Vanderbilt University Medical Center, 1211 21st Avenue South, Medical Arts Building, Suite 422, Nashville, TN 37212, USA. Electronic address:

Melatonin is involved in regulation of a variety of physiologic functions, including circadian rhythm, reproduction, mood, and immune function. Exogenous melatonin has demonstrated many clinical effects. Numerous clinical studies have documented improved sleep quality following administration of exogenous melatonin. Read More

Crit Care Clin 2019 Apr 23;35(2):229-245. Epub 2019 Jan 23.

Department of General Anesthesiology, Anesthesiology Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA; Center for Critical Care, Department of Outcomes Research, Cleveland Clinic, 9500 Euclid Avenue - G58, Cleveland, OH 44195, USA; Department of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, NC, USA. Electronic address:

The Angiotensin II for the Treatment of Vasodilatory Shock (ATHOS-3) trial demonstrated the vasopressor effects and catecholamine-sparing properties of angiotensin II. As a result, the Food and Drug Administration has approved angiotensin II for the treatment of vasodilatory shock. This review details the goals of treatment of vasodilatory shock in addition to the history, current use, and recent research regarding the use of angiotensin II. Read More

Cell Rep 2019 Feb;26(8):2227-2240.e5

Department of Microbiology, University of Washington School of Medicine, Seattle, WA 98105, USA; Department of Pediatrics, University of Washington School of Medicine, Seattle, WA 98105, USA; Pulmonary and Sleep Medicine, Seattle Children's Hospital, Seattle, WA 98105, USA. Electronic address:

Metagenomic sequencing is a promising approach for identifying and characterizing organisms and their functional characteristics in complex, polymicrobial infections, such as airway infections in people with cystic fibrosis. These analyses are often hampered, however, by overwhelming quantities of human DNA, yielding only a small proportion of microbial reads for analysis. In addition, many abundant microbes in respiratory samples can produce large quantities of extracellular bacterial DNA originating either from biofilms or dead cells. Read More

Immunity 2019 Feb;50(2):285-287

Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, New York University School of Medicine, New York, NY 10016, USA; Department of Cell Biology, New York University School of Medicine, New York, NY 10016, USA. Electronic address:

IgE antibodies are essential mediators of allergies. In a recent study in Science, Croote et al. (2018) characterize IgE cells isolated from individuals allergic to peanuts. Read More

Lancet Neurol 2019 Mar 12;18(3):307-318. Epub 2019 Feb 12.

Department of Psychiatry, Neurology, and Epidemiology and Biostatistics, University of California, San Francisco, CA, USA; San Francisco VA Medical Center, San Francisco, CA, USA.

Dysfunction in 24-h circadian rhythms is a common occurrence in ageing adults; however, circadian rhythm disruptions are more severe in people with age-related neurodegenerative diseases, including Alzheimer's disease and related dementias, and Parkinson's disease. Manifestations of circadian rhythm disruptions differ according to the type and severity of neurodegenerative disease and, for some patients, occur before the onset of typical clinical symptoms of neurodegeneration. Evidence from preliminary studies suggest that circadian rhythm disruptions, in addition to being a symptom of neurodegeneration, might also be a potential risk factor for developing Alzheimer's disease and related dementias, and Parkinson's disease, although large, longitudinal studies are needed to confirm this relationship. Read More

HERD 2019 Feb 20:1937586719827946. Epub 2019 Feb 20.

3 Department of Architecture, Kyungil University, Gyeongsan, South Korea.

Objectives:: Lighting is one of the environmental factors which can improve patient sleep in healthcare environments. Due to the high degree of variation in study designs and results on this topic, the implications have been difficult to interpret. This review consolidates studies on the impact of bright light exposure on sleep to identify lighting conditions that can be applied and researched in future healthcare environments. Read More

Behav Sleep Med 2019 Feb 20:1-8. Epub 2019 Feb 20.

a Department of Pediatrics and Neurology , MedStar Georgetown University Hospital , Washington , DC , USA.

Objectives: The relationship between repeated concussions and sleep disturbance is yet to be fully understood. The objective of this study was to examine the relationship between sleep disturbance, concussion duration, and repeated concussions by assessing postconcussive symptoms and cognition.

Methods: Subjects (ages 13-33 years) underwent postconcussion cognitive function evaluation and reported postconcussion symptoms including severity of disturbed sleep (drowsiness, trouble falling asleep, sleeping more than usual, and sleeping less than usual), mood disturbance (sadness, irritability, nervousness, and emotional lability), and headache. Read More

Eur J Cancer Care (Engl) 2019 Feb 19:e13020. Epub 2019 Feb 19.

Faculty of Health Sciences, Department of Nursing, Inonu University, Malatya, Turkey.

Introduction: This study was conducted to determine the effects of sleep hygiene education and reflexology on sleep quality and fatigue in the patients receiving chemotherapy.

Methods: The sample of the study consisted of 167 patients (84 in the experimental and 83 in the control group). The data were collected between October 2016 and November 2017 using an Introductory Information Form, the Pittsburgh Sleep Quality Index (PSQI) and the Fatigue Severity Scale (FSS). Read More

J Physiol 2019 Feb 19. Epub 2019 Feb 19.

Department of Psychiatry, University of California, San Diego, CA.

Key Points: Exercise elicits circadian phase-shifting effects, but additional information is needed. The phase-response curve describing the magnitude and direction of circadian rhythm phase shifts depending on the time of the zeigeber (time cue) stimulus is the most fundamental chronobiological tool for alleviating circadian misalignment and related morbidity. 51 older and 48 young adults followed a circadian rhythms measurement protocol for up to 5. Read More

Sleep Breath 2019 Feb 19. Epub 2019 Feb 19.

School of Biological Science and Medical Engineering and Research Institute, Beihang University, Shenzhen, China.

Objectives: To determine inter-lab reliability in sleep stage scoring using the 2014 American Academy of Sleep Medicine (AASM) manual. To understand in-depth reasons for disagreement and provide suggestions for improvement.

Methods: This study consisted of 40 all-night polysomnographys (PSGs) from different samples. Read More

Tremor Other Hyperkinet Mov (N Y) 2019 4;9:596. Epub 2019 Feb 4.

Ribeirão Preto School of Medicine, University of São Paulo, Ribeirão Preto, BR.

Background: Idiopathic focal dystonia is a motor syndrome associated with dysfunction of basal ganglia circuits. Observations have suggested that many other non-motor symptoms may also be part of the clinical picture. The aim was to assess the prevalence and correlation of non-motor symptoms in patients with common idiopathic focal or segmental dystonia. Read More

Exp Ther Med 2019 Mar 18;17(3):1766-1770. Epub 2018 Dec 18.

Department of Otolaryngology, Xuzhou Central Hospital, Xuzhou, Jiangsu 221009, P.R. China.

The present study investigated the changes of tumor necrosis factor-α (TNF-α), interleukin-8 (IL-8) and sleep ability in patients with obstructive sleep apnea hypopnea syndrome (OSAHS). A total of 684 patients who were admitted to Xuzhou Central Hospital between June 2012 and June 2016 were enrolled to serve as the experimental group and 192 healthy subjects were selected as the control group. Polysomnography was performed on both groups, and serum TNF-α and IL-8 levels were measured by ELISA. Read More

Am J Lifestyle Med 2018 Nov-Dec;12(6):479-483. Epub 2018 Aug 22.

Lee Health, Fort Myers, Florida (SL).

Most chronic illnesses in developed nations are largely preventable. Lifestyle Medicine adds tremendous value to traditional methods for the delivery of healthcare by focusing on preventing, reversing and treating chronic illness. By helping individuals focus on nutrition, physical activity, stress management, quality sleep, mental health and purposeful living, the risk and incidence of chronic illness decreases dramatically. Read More

Am J Lifestyle Med 2018 Nov-Dec;12(6):472-475. Epub 2018 Jun 14.

Department of Community Health and Preventive Medicine, Morehouse School of Medicine, Atlanta, Georgia.

The Optimal Health and Wellness Clinic of Morehouse Healthcare seeks to advance health equity by providing lifestyle medicine services to its predominantly African American patient population. Health equity means eliminating health disparities by providing services that meet the needs of the population served. African Americans have a higher burden of cardiovascular disease and diabetes than other American ethnic groups. Read More

Indian J Psychol Med 2019 Jan-Feb;41(1):32-37

Department of Community Medicine, Government Medical College, Vidisha, Madhya Pradesh, India.

Background: Depression is a common problem in the elderly but is often undetected and ignored as a medical problem, leading to poor quality of life. This community-based study was conducted to know the burden and risk factors of depression among the elderly.

Subjects And Methods: The survey was done in 2015 in Maharashtra, India as a part of an initiative addressing community mental health needs of the elderly. Read More

Nature 2019 Feb;566(7744):329-330

Nat Commun 2019 Feb 19;10(1):837. Epub 2019 Feb 19.

Department of Clinical Biochemistry, Molecular Sleep Laboratory, Rigshospitalet, 2600 Glostrup, Denmark.

Narcolepsy Type 1 (NT1) is a neurological sleep disorder, characterized by the loss of hypocretin/orexin signaling in the brain. Genetic, epidemiological and experimental data support the hypothesis that NT1 is a T-cell-mediated autoimmune disease targeting the hypocretin producing neurons. While autoreactive CD4 T cells have been detected in patients, CD8 T cells have only been examined to a minor extent. Read More

BMJ Open 2019 Feb 19;9(2):e025939. Epub 2019 Feb 19.

Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.

Purpose: A prospective cohort study for pregnant women, the Maternity Log study, was designed to construct a time-course high-resolution reference catalogue of bioinformatic data in pregnancy and explore the associations between genomic and environmental factors and the onset of pregnancy complications, such as hypertensive disorders of pregnancy, gestational diabetes mellitus and preterm labour, using continuous lifestyle monitoring combined with multiomics data on the genome, transcriptome, proteome, metabolome and microbiome.

Participants: Pregnant women were recruited at the timing of first routine antenatal visits at Tohoku University Hospital, Sendai, Japan, between September 2015 and November 2016. Of the eligible women who were invited, 65. Read More

BMJ Open 2019 Feb 19;9(2):e024695. Epub 2019 Feb 19.

Department of Neurology, McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, Texas, USA.

Introduction: Hypertension is a major risk factor for recurrent stroke, and blood pressure (BP) reduction is associated with decreased risk of stroke recurrence. However, many stroke survivors have poorly controlled BP after their initial stroke. The Stroke Transitions Education and Prevention (STEP) Clinic was established to provide a comprehensive approach to stroke risk factor reduction. Read More

BMJ Open 2019 Feb 19;9(2):e022306. Epub 2019 Feb 19.

Faculty of Health Sciences of Trairi - UFRN/FACISA, Federal University of Rio Grande do Norte, Santa Cruz, Brazil.

Introduction: Physical exercises have been recommended to improve the overall well-being of patients with fibromyalgia, with the main objective of repairing the effects of lack of physical conditioning and of improving the symptoms, especially pain and fatigue. Although widely recommended and widely known, few studies support the use of Pilates as an effective method in improving the symptoms of the disease, comparing it with other well-founded exercise modalities. This protocol was developed to describe the design of a randomised controlled study with a blind evaluator that evaluates the effectiveness of mat Pilates, comparing it with aquatic aerobic exercises, in improving pain in women with fibromyalgia. Read More

BMJ Open 2019 Jan 25;9(1):e023742. Epub 2019 Jan 25.

LIEN, EA4685, University of Western Brittany (UBO), Brest, France.

Introduction: The main symptom of fibromyalgia (FM) is diffuse pain. There is currently no aetiological treatment for FM. However, all pain associations and best practice guidelines strongly advocate the practice of aerobic physical activity to improve the symptoms of FM subjects. Read More

MBio 2019 Feb 19;10(1). Epub 2019 Feb 19.

Department of Pediatrics, Division of Pulmonary, Allergy and Immunology, Cystic Fibrosis, and Sleep, Emory University School of Medicine, Atlanta, Georgia, USA

is an opportunistic pathogen that causes chronic lung infections in people with cystic fibrosis (CF). Chronic isolates generally do not express O antigen and often have a mucoid phenotype, which is characterized by the overproduction of the exopolysaccharide alginate. Therefore, O antigen expression and the mucoid phenotype may be coordinately regulated upon chronic adaption to the CF lung. Read More

Epileptic Disord 2019 Feb 18. Epub 2019 Feb 18.

Grenoble-Alpes Hospital and University - Neurology Department and GIN INSERM U-1216, Grenoble, France.

This educational review describes the classification of paroxysmal events and a four-dimensional epilepsy classification system. Paroxysmal events are classified as epileptic and non-epileptic paroxysmal events. Non-epileptic events are, in turn, classified as psychogenic and organic paroxysmal events. Read More

Epileptic Disord 2019 Feb 18. Epub 2019 Feb 18.

Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.

Obstructive sleep apnea affects up to 30% of patients with epilepsy. As obstructive sleep apnea represents a clinical risk factor for cognitive deficits, its occurrence in epilepsy patients may exacerbate cognitive deficits associated with this condition. However, the cognitive burden of obstructive sleep apnea in epilepsy remains poorly understood. Read More

Epileptic Disord 2019 Feb 18. Epub 2019 Feb 18.

Department of Neurology and South Texas Comprehensive Epilepsy Center, UT Health San Antonio, San Antonio, Texas.

Since lacosamide was approved as an adjuvant agent for the treatment of medically refractory focal epilepsy over ten years ago, it is becoming more widely used for the treatment of idiopathic (genetic) generalized epilepsies. Several studies have demonstrated efficacy in reducing primary generalized tonic-clonic seizures (GTCS), but efficacy is less well-characterized for myoclonic and absence seizures. A 29-year-old man with juvenile myoclonic epilepsy and medically refractory GTCS on a combination of levetiracetam and topiramate was started on lacosamide adjunctive therapy with the plan to replace topiramate. Read More

J Pediatr Nurs 2019 Feb 16. Epub 2019 Feb 16.

Jordan University of Science and Technology, P.O. Box (3030), Irbid 22110, Jordan. Electronic address:

Purpose: This study aimed at assessing the effect of short duration Skin to skin contact (SSC) (5 days) on premature infants' short-term physiological and behavioral outcomes.

Design And Methods: A quasi-experimental control group design was utilized. 89 stable premature infants were allocated to either an interventional or control group. Read More

J Psychosom Res 2019 Mar 7;118:18-26. Epub 2019 Jan 7.

Department of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, IA, USA; Iowa Neuroscience Institute, Carver College of Medicine, University of Iowa, Iowa City, IA, USA; Department of Pulmonary, Critical Care, and Sleep Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA, USA. Electronic address:

Objectives: To compare the frequency of anxiety/depressive symptoms and use of anxiolytic-hypnotics/antidepressants in smokers with and without COPD and to identify characteristics associated with having unmedicated symptoms.

Methods: Cross-sectional analysis of ambulatory, current/former smokers ≥10 pack years enrolled in the COPDGene study. We measured anxiety/depressive symptoms using the Hospital Anxiety and Depression Scale (subscales ≥8), recorded anxiolytic-hypnotic/antidepressant use, and defined unmedicated symptoms as elevated anxiety/depressive symptoms and not on medications. Read More

J Psychosom Res 2019 Mar 5;118:1-8. Epub 2019 Jan 5.

Department of Environmental Health, National Institute of Public Health, Wako 351-0197, Japan. Electronic address:

Objective: Chemical intolerance (CI) has become a strong public health concern in industrialized countries. The Japanese Chemical Intolerance (JCI) study was conducted in January 2012 with a cohort of 7245 adults from population-based sampling as the baseline. The aim of the present study was to investigate the factors involved in the improvement and development of CI from the five-year follow-up study. Read More

Lancet 2019 Feb 14;393(10172):639. Epub 2019 Feb 14.

Scripps Research Translational Institute, La Jolla, CA 92037, USA.

Cell Mol Biol (Noisy-le-grand) 2019 Jan 31;65(1):46-51. Epub 2019 Jan 31.

Department of Medical Pharmacology, Faculty of Medicine, Yeditepe University, Istanbul, Turkey.

Obstructive sleep apnea syndrome (OSAS) is a highly prevalent disorder which results in markedly reduced (hypopnea) or absent (apnea) airflow at the nose/mouth. Since vitamin D deficiency has found in an association with some disorders it is thought to be related with OSAS progression. The aim of this study is to investigate the association between VDR, VDBP mutations, vitamin D level and some environmental risk factors with OSAS. Read More

BMC Gastroenterol 2019 Feb 19;19(1):34. Epub 2019 Feb 19.

Future Medicine Division, Korea Institute of Oriental Medicine, Daejeon, 1672, Republic of Korea.

Background: This study was conducted to analyze the association between digestive symptoms and sleep disturbance, and to determine if any digestive symptoms are related to sleep disturbance.

Methods: This was a cross-sectional study of 5792 subjects surveyed in a community-based cohort. Subjects provided information regarding the quality of sleep as assessed by the Pittsburgh Sleep Quality Index (PSQI), as well as digestive symptoms as assessed by the Gastrointestinal Symptom Rating Scale (GSRS). Read More

Int J Vitam Nutr Res 2019 Feb 20:1-7. Epub 2019 Feb 20.

3 Department of Neurology, Bahcesehir University, Medical Park Goztepe Hospital, Istanbul, Turkey.

Observational studies performed in homogeneous groups to objectively investigate the cause and effect relationship between vitamin D deficiency and sleep disorders are scarce. In this study, it was aimed to analyze the relationship between the severity of OSAS and vitamin-D levels among the participants whose features affecting serum vit-D levels were minimised. Serum 25-OH vitamin-D levels in 121 OSAS Male patients diagnosed by polysomnography without any systemic disease or vitamin-D supplement that may effect the vitamin-D metabolism were measured. Read More

Health Informatics J 2019 Feb 19:1460458219827349. Epub 2019 Feb 19.

Keio University, Japan.

Getting enough quality sleep plays a vital role in protecting our mental health, physical health, and quality of life. Sleep deprivation can make it difficult to concentrate on daily activities, and lower sleep quality is associated with hypertension, hyperglycemia, and hyperlipidemia. The amount of sleep we get is important, but in recent years, quality sleep has also been deemed significant. Read More

Clin Pediatr (Phila) 2019 Feb 19:9922819832030. Epub 2019 Feb 19.

1 Nationwide Children's Hospital, Columbus, OH, USA.

Self-administered treatments may overcome access barriers to evidence-based care for pediatric sleep problems. Two hundred thirty-nine families participated in a randomized controlled trial with 3 study arms: a DVD intervention condition (the Sleep Easy Solution), a Website comparison condition, and a Wait-List comparison condition. The primary outcome was trichotomous-Do you consider your child's sleep a problem? (not a problem at all, a small problem, a very serious problem). Read More

Ann Otol Rhinol Laryngol 2019 Feb 19:3489419831715. Epub 2019 Feb 19.

1 The Sleep Medicine Center, Shengjing Hospital, China Medical University, Shenyang, Liaoning, China.

Objectives:: The treatment of hemangiomas in the hypopharynx and larynx can be challenging and stressful because of the high tumor recurrence rate. The objective of this study was to investigate the therapeutic effect of the combination of intratumor injection of bleomycin and electroresection/electrocautery on the hemangiomas in the hypopharynx and larynx through suspension laryngoscopy.

Methods:: With patients under general anesthesia, the hemangiomas were fully exposed through suspension laryngoscopy. Read More