219,458 results match your criteria Skull Base Petrous Apex Infection


Healed impact trauma to a Neolithic cattle frontal bone: A posthuman perspective.

Int J Paleopathol 2018 Dec 3;24:197-200. Epub 2018 Dec 3.

School of Archaeology and Ancient History, University of Leicester, University Road, Leicester, LE1 7RH, UK. Electronic address:

Trauma associated with slaughter is identified occasionally archaeologically in the cranial remains of domesticated animals, with evidence for pole-axing occurring in Europe, especially from the Roman period onwards. The injury typically extends through the frontal bone and sinuses to penetrate the braincase, causing haemorrhage, loss of consciousness, brain damage, and death. Evidence for slaughter methods in the British Neolithic, however, is lacking. Read More

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December 2018
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Epithelioid Osteoblastoma of the Temporal Bone: A Case Report.

World Neurosurg 2018 Dec 3. Epub 2018 Dec 3.

Department of Pathology, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital.

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December 2018
1 Read

Ultrasonic scalpel-assisted endoscopic endonasal surgery of infratemporal fossa: our first impressions.

World Neurosurg 2018 Dec 3. Epub 2018 Dec 3.

Division of Otorhinolaryngology, Department of Biotechnology and Life Sciences, HNS&FDRc, University of Insubria, Varese, Italy.

Background: Endoscopic endonasal transpterygoid approach is emerging as a valid option for treating selected tumors in the infratemporal fossa. Compared to traditional open approaches, the endoscopic endonasal approach (EEA) presents more difficulty in controlling bleeding and less choice in surgical instruments for endoscopic tumor dissection, which is often performed with bipolar forceps or steel dissectors.

Case Description: We describe the use of an ultrasonic scalpel device for performing endoscopic endonasal resection of two rare infratemporal fossa tumors (mature teratoma and hemangiopericytoma), which has not been reported in the literature so far. Read More

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December 2018
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Middle Meningeal Artery to Premeatal Anterior Inferior Cerebellar Artery Bypass Via Anterior Petrosectomy: An Anatomic Feasibility Study.

World Neurosurg 2018 Dec 3. Epub 2018 Dec 3.

Department of Neurological Surgery, University of California, San Francisco, California, USA; Skull Base and Cerebrovascular Laboratory, University of California, San Francisco, California, USA. Electronic address: http://skullbaselab.ucsf.edu.

Introduction: Anterior-inferior cerebellar artery (AICA) aneurysms are rare with no optimal consensus on management strategies. When the treatment requires parent artery occlusion post-operative ischemic or neuropathic, complications can occur.

Objective: To evaluate the feasibility of direct revascularization of premeatal AICA using the middle meningeal artery (MMA) as the donor through an anterior petrosectomy (APA) window. Read More

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December 2018

Whole genome variant association across 100 dogs identifies a frame shift mutation in DISHEVELLED 2 which contributes to Robinow-like syndrome in Bulldogs and related screw tail dog breeds.

PLoS Genet 2018 Dec 6;14(12):e1007850. Epub 2018 Dec 6.

Department of Population Health and Reproduction, School of Veterinary Medicine, University of California Davis, Davis, CA, United States of America.

Domestic dog breeds exhibit remarkable morphological variations that result from centuries of artificial selection and breeding. Identifying the genetic changes that contribute to these variations could provide critical insights into the molecular basis of tissue and organismal morphogenesis. Bulldogs, French Bulldogs and Boston Terriers share many morphological and disease-predisposition traits, including brachycephalic skull morphology, widely set eyes and short stature. Read More

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December 2018
4 Reads

Rediscovered identity of the scaphocephalic skull housed in the museum of the Department of Anatomy of the Medical College of the Jagiellonian University.

Folia Med Cracov 2018 ;58(3):5-10

Department of Anatomy, Jagiellonian University Medical College Kopernika 12, Kraków, Poland.

A personal data referring to the scaphoid skull housed in the Department of Anatomy of the Jagiellonian University, Medical College was established thanks to reviewing 19th century literature performed by Dr. Soficaru. We received information that the skull had belonged to an adult man who was a carpenter, born at Cracow. Read More

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January 2018
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Utility of first positron emission tomography-computed tomography scan as a prognostic tool following treatment of sinonasal and skull base malignancies.

Head Neck 2018 Dec 6. Epub 2018 Dec 6.

Department of Otolaryngology Head and Neck Surgery and Maxillofacial Surgery, Tel-Aviv Sourasky Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

Background: The prognostic value of the first posttreatment whole body integrated positron emission tomography-computed tomography (PET/CT) scanning in patients with sinonasal/skull base malignancies is undetermined.

Methods: We retrospectively reviewed the data of all patients that underwent surgery for sinonasal/skull base malignancies in 2000-2015. The results of the pretreatment and posttreatment PET/CT findings and the clinical course were retrieved. Read More

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December 2018

Lack of Sphenoid Pneumatization Does Not Affect Endoscopic Endonasal Pediatric Skull Base Surgery Outcomes.

Laryngoscope 2018 Dec 5. Epub 2018 Dec 5.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania.

Objectives/hypothesis: Currently, due to the rarity of pathology, there are limited data surrounding outcomes of pediatric skull base surgery. Traditionally, surgeons have proceeded with caution when electing endonasal endoscopic transsellar/transplanum approaches to the skull base in pediatric patients due to poor sphenoid pneumatization. In this study, we review outcomes of endoscopic pediatric skull base surgery based on sphenoid pneumatization patterns. Read More

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December 2018
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Interplay of Tumor Spread, Volume and Epstein-Barr Virus DNA in Nasopharyngeal Carcinoma: Feasibility of An Integrative Risk Stratification Scheme.

J Cancer 2018 20;9(22):4271-4278. Epub 2018 Oct 20.

Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.

To investigate the inter-correlation of tumor spread, volume and quantitative plasma Epstein-Barr virus DNA level (pEBV DNA), and to further assess the prognostic efficacy of a novel risk stratification combining anatomic, volumetric and biological features in nasopharyngeal carcinoma (NPC). One hundred and twelve patients with non-metastatic NPC were prospectively enrolled. Correlation of pEBV DNA with tumor invasiveness, lymph node (LN) metastasis, tumor volume and classification was tested by univariate and multivariate analyses. Read More

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October 2018

Three-dimensional volumetric magnetic resonance imaging (MRI) analysis of the soft palate and nasopharynx in brachycephalic and non-brachycephalic dog breeds.

J Vet Med Sci 2018 Dec 5. Epub 2018 Dec 5.

Section of Medical Imaging, Veterinary Medical Center, Chungbuk National University.

The purpose of this study was to use magnetic resonance imaging (MRI) to compare the volumes and three-dimensional configurations of the soft palate and nasopharynx in non-brachycephalic and brachycephalic dogs with different body weights, and infer which factors influence nasopharyngeal volume. This was a retrospective observational study. The brain MRI medical records of all dogs referred to the Veterinary Medical Center, Chungbuk National University, between 2013 and 2016, for evaluation of intracranial disease were reviewed. Read More

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December 2018
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Diagnostic and prognostic value of the optic nerve sheath diameter with respect to the intracranial pressure and neurological outcome of patients following hemicraniectomy.

BMC Neurol 2018 Dec 5;18(1):199. Epub 2018 Dec 5.

Department of Emergency Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, No. 88, Jiefang Road, Hangzhou City, 310009, Zhejiang Province, China.

Background: In cases showing cerebrospinal fluid (CSF) redistribution as a compensatory mechanism in acute intracranial hypertension, the optic nerve sheath diameter (ONSD) can be used to estimate intracranial pressure (ICP). However, it remains unclear whether the ONSD can be applied in patients with skull defects after a craniectomy, because the primary injury or surgical craniectomy may alter the dynamics of the CSF circulation or structure of the optical nerve sheath. This study explored the value of the ONSD in patients after a hemicraniectomy. Read More

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December 2018

Reconstruction of calvarial bone defects using poly(amino acid)/hydroxyapatite/calcium sulfate composite.

J Biomater Sci Polym Ed 2018 Dec 6:1-21. Epub 2018 Dec 6.

a College of Physical Science and Technology, Sichuan University , Chengdu 610064 , China.

The aim of this study was to evaluate the thermal properties and in vivo interface performance of poly(amino acid) (PAA) and a composite containing PAA, hydroxyapatite (HA), and calcium sulfate (CS), with respect to their suitability for skull repair. Biocompatibility was evaluated by implantation of materials into muscles of rabbits for eight weeks. Skull repair was assessed by implanting PAA, the compact PAA/HA/CS composite (c-PAA/HA/CS), and a one-side-porous PAA/HA/CS composite (p-PAA/HA/CS) into rabbit calvarial defects. Read More

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December 2018
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EFFECTS OF THE SCAN RANGE ON RADIATION DOSE IN THE COMPUTED TOMOGRAPHY COMPONENT OF ONCOLOGY POSITRON EMISSION TOMOGRAPHY/COMPUTED TOMOGRAPHY.

Radiat Prot Dosimetry 2018 Dec 1. Epub 2018 Dec 1.

Department of Radiology, Kitasato University Hospital, Kitasato, Minami-ku, Sagamihara, Kanagawa, Japan.

We performed phantom experiments to investigate radiation dose in the computed tomography component of oncology positron emission tomography/computed tomography in relation to the scan range. Computed tomography images of an anthropomorphic whole-body phantom were obtained from the head top to the feet, from the head top to the proximal thigh or from the skull base to the proximal thigh. Automatic exposure control using the posteroanterior and lateral scout images offered reasonable tube current modulation corresponding to the body thickness. Read More

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December 2018

Anterior Cranial Vault Reconstruction With Distraction for Primary and Secondary Craniosynostosis Repair.

J Craniofac Surg 2018 Nov 30. Epub 2018 Nov 30.

Division of Plastic and Reconstructive Surgery, University of Nebraska Medical Center, Omaha, NE.

Traditional fronto-orbital advancement continues to be a useful operation for correction of craniosynostosis involving the coronal or metopic sutures. Recently, distraction osteogenesis has been used to correct a variety of cranial deformities. Studies have mostly focused on posterior vault distraction due to its simplicity and greater volume gain when compared with anterior vault distraction. Read More

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November 2018

Using Computer-Aided Design/Computer-Aided Manufacturing for Autogenous, Split Calvarial Bone Graft-based Cranioplasty: Optimizing Reconstruction of Large, Complex Skull Defects.

J Craniofac Surg 2018 Nov 30. Epub 2018 Nov 30.

Department of Plastic and Reconstructive Surgery, Johns Hopkins Hospital, Baltimore, MD.

Background: While autologous split calvarial bone is an ideal graft material in cranioplasty, selection of a donor site can be challenging and limited in the reconstruction of complicated cranial defects. Computer-aided design and manufacturing (CAD/CAM) may improve donor-site harvest and contouring and mitigate operative complications in split calvarial bone graft-based cranioplasty for complex patients, but has not previously been studied in this unique setting.

Methods: In this study, a retrospective review of patients who presented to the institution and underwent split-calvarial bone graft-based cranioplasty using CAD/CAM to optimize reconstruction of full-thickness cranial defects ≥30 cm was performed. Read More

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November 2018

Multiple Variations at the Base of an Adult Skull: Implications in Radiology and Skull Base Surgery.

J Craniofac Surg 2018 Nov 30. Epub 2018 Nov 30.

Melaka Manipal Medical College (Manipal Campus), Manipal Academy of Higher Education, Manipal, India.

Knowledge of variations at the base of the skull may be important for academic, anthropological, forensic, and clinical purposes, especially in computed tomography and magnetic resonance imaging and while performing safe radical surgery. This report presents multiple variations at the base of an adult Indian skull. The variations noted include the presence of foramen of Civinini bilaterally, absence of carotid canal on the left side, reduced size of foramen lacerum on the left side, presence of petro-occipital foramen bilaterally, asymmetry between the jugular fossae, and asymmetrical occipital condyles. Read More

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November 2018

The rhinologist's role in the management of rathke's cleft cysts.

Curr Opin Otolaryngol Head Neck Surg 2018 Nov 16. Epub 2018 Nov 16.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadephia, Pennsylvania, USA.

Purpose Of Review: To review the recent literature regarding the growing role of rhinologists and otolaryngologists with neurosurgeons in the joint multidisciplinary team approach for managing patients with Rathke's cleft cysts (RCC).

Recent Findings: The transnasal endoscopic approach to the skull base has become relatively mainstream for surgical treatment of RCCs. Suprasellar lesions, especially those that are purely suprasellar, are associated with higher recurrence rates, though an extended approach may improve dissection and access and therefore aid in lesion removal. Read More

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November 2018

Current indications for balloon sinuplasty.

Curr Opin Otolaryngol Head Neck Surg 2018 Nov 30. Epub 2018 Nov 30.

Rhinology & Endoscopic Skull Base Surgery, UCLA Department of Head & Neck Surgery, Los Angeles, California, USA.

Purpose Of Review: The purpose of the review is to evaluate the current indications and contraindications for balloon sinuplasty and review the clinical trials performed in this area.

Recent Findings: The indications for balloon sinus dilatation are somewhat similar to those for endoscopic sinus surgery. Balloon sinus ostial dilation (BSD) has been found to be most effective in the treatment of recurrent acute sinusitis (RARS) and chronic rhinosinusitis without nasal polyposis (CRSsNP) that has been refractory to medical therapy. Read More

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November 2018
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Results and limits of posterior cranial vault expansion by osteotomy and internal distractors.

Surg Neurol Int 2018 30;9:217. Epub 2018 Oct 30.

Craniofacial Unit, Department of Pediatric Neurosurgery, Hôpital Necker-Enfants Malades, Paris, France.

Background: Expanding the posterior cranial vault has become a common procedure in the treatment of complex craniosynostosis. Several techniques are available to remodel the posterior vault. Aim of this study was to analyze the posterior vault distraction osteogenesis. Read More

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October 2018

Impact of extra-axial cerebrospinal fluid collection in frontal morphology after surgical treatment of scaphocephaly.

Surg Neurol Int 2018 30;9:215. Epub 2018 Oct 30.

Departement of Pediatric Neurosurgery, Craniofacial Unit, Necker Enfants Malades Hospital, APHP, Paris, France.

Background: Infants with sagittal suture synostosis often present a pathologic dilatation of subarachnoid spaces. The impact of such subarachnoid spaces' enlargement in the morphology of the skull, especially on the forehead and on the surgical outcome, was analyzed.

Methods: Children less than 6 months of age undergoing a surgical correction of the scaphocephaly with Renier's H technique between 2003 and 2008 were included in the study. Read More

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October 2018

Bones, Glands, Ears and More: The Multiple Roles of FGF10 in Craniofacial Development.

Front Genet 2018 16;9:542. Epub 2018 Nov 16.

Program in Craniofacial Biology, Departments of Orofacial Sciences and Pediatrics, Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, United States.

Members of the fibroblast growth factor (FGF) family have myriad functions during development of both non-vertebrate and vertebrate organisms. One of these family members, , is largely expressed in mesenchymal tissues and is essential for postnatal life because of its critical role in development of the craniofacial complex, as well as in lung branching. Here, we review the function of FGF10 in morphogenesis of craniofacial organs. Read More

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November 2018

Additive value of Technetium methylene diphosphonate hybrid single-photon emission computed tomography/computed tomography in the diagnosis of skull base osteomyelitis in otitis externa patients compared to planar bone scintigraphy.

World J Nucl Med 2018 Oct-Dec;17(4):286-292

Department of Oncology and Nuclear Medicine, Faculty of Medicine, Cairo University, Cairo, Egypt.

The aim of this study was to evaluate the additive value of technetium methylene diphosphonate (Tc-MDP) hybrid single-photon emission computed tomography/computed tomography (SPECT-CT) in the diagnosis of skull base osteomyelitis (SBO) compared to planar bone scintigraphy (PBS). This was a single institution; prospective study included 23 patients with otitis externa, clinically suspected of SBO, all of them were diabetic. Three-phase bone scintigraphy and SPECT/CT were performed to all patients. Read More

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December 2018

F-fluorodeoxyglucose positron emission tomography/computed tomography in carcinoma of unknown primary: A subgroup-specific analysis based on clinical presentation.

World J Nucl Med 2018 Oct-Dec;17(4):219-222

Radiation Medicine Centre, Bhabha Atomic Research Centre, Tata Memorial Centre Annexe, Parel, Maharashtra, India.

The aim of this study was to explore the clinical efficacy of F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) in tumor detection in patients with proven or suspected carcinoma of unknown primary origin (CUP) and making a subgroup-specific analysis. This was a retrospective, cross-sectional survey of patients with CUP syndrome who were referred for F-FDG PET-CT studies over a 2-year period. FDG-PET-CT scans were performed in compliance with the standard whole-body protocol, i. Read More

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December 2018
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Tooth Loss Precedes the Origin of Baleen in Whales.

Curr Biol 2018 Nov 21. Epub 2018 Nov 21.

Department of Atmospheric, Oceanic, and Earth Sciences, George Mason University, 4400 University Drive, Fairfax, VA 22030, USA.

Whales use baleen, a novel integumentary structure, to filter feed; filter feeding itself evolved at least five times in tetrapod history but demonstrably only once in mammals [1]. Living baleen whales (mysticetes) are born without teeth, but paleontological and embryological evidence demonstrate that they evolved from toothed ancestors that lacked baleen entirely [2]. The mechanisms driving the origin of filter feeding in tetrapods remain obscure. Read More

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November 2018

Langerhans cell histiocytosis of the skull in the burr-hole site covered with hydroxyapatite material: a case report.

World Neurosurg 2018 Nov 29. Epub 2018 Nov 29.

Department of Neurosurgery, Ebina General Hospital, Kanagawa, Japan.

Background: We present a case report of a male patient with Langerhans cell histiocytosis (LCH), which occurred in a burr-hole site for chronic subdural hematoma covered with hydroxyapatite material. LCH is a rare dendritic histiocytic disorder that affects the bones, especially the skull. Until now, the association with foreign-body reaction has rarely been reported by any author. Read More

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November 2018
2 Reads

Meningiomas display a specific immunoexpression pattern in a rostrocaudal gradient: An analysis of 366 patients.

World Neurosurg 2018 Nov 29. Epub 2018 Nov 29.

Neurosurgery, School of Medicine. Electronic address:

Background: Meningiomas are heterogenous with differences in anatomical, histopathological and clinical characteristics. Such spatial variability in meningioma biology is thought to be due to differences in expression
of critical developmental regulators. We hypothesized that variability in meningioma biology follows gradients as in embryology and tested a cohort of 366 meningiomas for histopathological and immunohistochemical gradients. Read More

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November 2018

Vertical bone regeneration with synthetic biomimetic calcium phosphate onto the calvaria of rats.

Tissue Eng Part C Methods 2018 Dec 1. Epub 2018 Dec 1.

University of Nantes , Faculty of Medicine , Inserm UMR 957 - Lab. pathophsyiology of bone resorption , 1 rue Gaston Veil , Nantes, France , 44035 ;

Bone regeneration is often required to provide adequate oral rehabilitation before dental implants. Vertical ridge augmentation is the most challenging of all situations and often requires the use of autologous bone grafting. However, autologous bone grafting induces morbidity and the harvestable bone is limited in quantity. Read More

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December 2018

Honey as a Treatment in Otorhinolaryngology: A Review by Subspecialty.

Ann Otol Rhinol Laryngol 2018 Dec 2:3489418815188. Epub 2018 Dec 2.

3 Department of Head and Neck Surgery, University of California, Los Angeles, California, USA.

Objectives:: To provide an up-to-date review of honey's effectiveness and potential applications in otorhinolaryngology.

Methods:: A literature search of the online databases PubMed, EMBASE, and Cochrane Central Register of Controlled Trials was conducted.

Results:: Sixty-three studies were identified within head and neck surgery (n = 23, 36%); pediatric otolaryngology (n = 18, 29%); rhinology, sinus, and skull base surgery (n = 11, 17%); otology (n = 6, 10%), facial plastic and reconstructive surgery (n = 3, 5%); and laryngology (n = 2, 3%). Read More

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December 2018

Posterior Maxillary Sinus Wall: A Landmark for Identifying the Sphenoid Sinus Ostium.

Ann Otol Rhinol Laryngol 2018 Dec 3:3489418816725. Epub 2018 Dec 3.

1 Department of Otolaryngology-Head and Neck Surgery, University of California, Davis, Sacramento, CA, USA.

Importance:: Safe entry into sphenoid sinus is critical in endoscopic sinus and skull base surgery. A number of surgical landmarks have been used to identify the sphenoid sinus ostium during endoscopic endonasal surgery with variable reliability and intraoperative feasibility.

Objective:: To determine if the posterior wall of the maxillary sinus is a reliable landmark to determine the depth of the sphenoid sinus ostium during anterior to posterior dissection. Read More

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December 2018

Direct CNS delivery of proteins using thermosensitive liposome-in-gel carrier by heterotopic mucosal engrafting.

PLoS One 2018 5;13(12):e0208122. Epub 2018 Dec 5.

Department of Pharmaceutical Sciences, School of Pharmacy, Northeastern University, Boston, MA, United States of America.

Delivering therapeutics across the blood-brain barrier (BBB) for treating central nervous system (CNS) diseases is one of the biggest challenges today as the BBB limits the uptake of molecules greater than 500 Da into the CNS. Here we describe a novel trans-nasal mucosal drug delivery as an alternative to the intranasal drug delivery to overcome its limitations and deliver high molecular weight (HMW) therapeutics efficiently to the brain. This approach is based on human endoscopic skull base surgical techniques in which a surgical defect is repaired by engrafting semipermeable nasal mucosa over a skull base defect. Read More

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December 2018

Systemic Changes Affecting the Morphology of Calvarial Bone.

J Craniofac Surg 2018 Dec 3. Epub 2018 Dec 3.

Division of Plastic and Reconstructive Surgery, Department of Surgery, Mount Sinai Hospital.

Plastic surgeons are frequently consulted to evaluate concerns about a patient's skull. Imaging studies often reveal abnormalities in bone morphology, from increased porosity to sclerotic changes. While focal findings imply a benign or malignant neoplasm, the etiology of more diffuse findings can be more varied, making the correct diagnosis challenging. Read More

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December 2018
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Ergonomics in endoscopic sinus surgery.

Curr Opin Otolaryngol Head Neck Surg 2018 Dec 3. Epub 2018 Dec 3.

Departments of Otolaryngology and Neurosurgery, University of Colorado School of Medicine, Aurora, Colorado, USA.

Purpose Of Review: Awareness of ergonomics is growing into surgical specialties including otolaryngology. Most otolaryngologists experience occupational physical discomfort, and daily incorporation of standard ergonomic principles may alleviate some of this pain.

Recent Findings: Further demonstration of surgery-related physical discomfort has been documented based on surveys of general otolaryngologists and subspecialty rhinologists. Read More

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December 2018

Experiences with a temporary synthetic skin substitute after decompressive craniectomy: a retrospective two-center analysis.

Acta Neurochir (Wien) 2018 Dec 4. Epub 2018 Dec 4.

Department of Neurosurgery, Trauma Center Murnau, Professor-Küntscher Straße 8, 82418, Murnau, Germany.

Background: Decompressive craniectomy is a commonly performed procedure. It reduces intracranial pressure, improves survival, and thus might have a positive impact on several neurosurgical diseases and emergencies. Sometimes primary skin closure is not possible due to cerebral herniation or extensive skin defects. Read More

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December 2018
1 Read

Braincase and endocranial anatomy of two thalattosuchian crocodylomorphs and their relevance in understanding their adaptations to the marine environment.

PeerJ 2018 26;6:e5686. Epub 2018 Nov 26.

CONICET. División Paleontología Vertebrados, Museo de La Plata, Facultad de Ciencias Naturales y Museo, Universidad Nacional de La Plata, La Plata, Buenos Aires, Argentina.

Thalattosuchians are a group of Mesozoic crocodylomorphs known from aquatic deposits of the Early Jurassic-Early Cretaceous that comprises two main lineages of almost exclusively marine forms, Teleosauridae and Metriorhynchoidea. Teleosaurids were found in shallow marine, brackish and freshwater deposits, and have been characterized as semiaquatic near-shore forms, whereas metriorhynchids are a lineage of fully pelagic forms, supported by a large set of morphological characters of the skull and postcranial anatomy. Recent contributions on Thalattosuchia have been focused on the study of the endocranial anatomy. Read More

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November 2018

Assessment of the Prevalence of Vascular Anomalies of the Circle of Willis Based on the Autopsy of Cadavers in Kurdish Race Between 2016 and 2017.

Mater Sociomed 2018 Oct;30(3):189-192

Department of Neurosurgery, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Introduction: Cerebral arterial variations are commonly associated with cerebrovascular disease and should be considered during brain surgeries. Since some cerebrovascular diseases are seen in certain breeds, it seems that different distributions of cerebral arterial variations depend on race.

Aim: The aim of this study was to determine the random incidence of vascular anomalies of the circle of Willis in autopsy of the cadavers. Read More

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October 2018

Gaetano Zumbo's anatomical wax model: From skull to cranium.

Prog Brain Res 2018 28;243:75-105. Epub 2018 Nov 28.

Department of History of Art, UCL, London, United Kingdom. Electronic address:

Gaetano Giulio Zumbo's anatomical model of a head, executed in the late seventeenth century and now in Florence's La Specola, is the earliest known life-size wax model for use in study and research. The model conjoins experimental wax techniques with human matter such as hair, teeth and bone, and confronts the observer not only with the interior of the head but also with the face, brutally dissected and in the process of decomposing. By contrast, the back of the head offers an entirely different display, an actual human cranium cut across its upper part and revealing carefully dissected and vibrantly modeled sections of the brain. Read More

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November 2018
1 Read

Long-term Outcome for Open and Endoscopically Resected Sinonasal Tumors.

Otolaryngol Head Neck Surg 2018 Dec 4:194599818815881. Epub 2018 Dec 4.

6 Department of Otorhinolaryngology, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.

Objective: Endoscopic resection of sinonasal cancer has become an alternative to open craniofacial surgery and leads to safe and satisfying results in emerging numbers. Randomized study data comparing outcomes between approaches are missing. Hence, it remains unclear which subgroups of patients might profit most from each technique. Read More

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December 2018

NKX3.1 and PSMA are sensitive diagnostic markers for prostatic carcinoma in bone metastasis after decalcification of specimens.

Am J Clin Exp Urol 2018 20;6(5):182-188. Epub 2018 Oct 20.

Department of Pathology, School of Medicine, New York University New York, NY, USA.

Background: Prostate specific antigen (PSA), prostate specific membrane antigen (PSMA), and NKX3.1 are sensitive and prostate-specific markers frequently used for the diagnosis of metastatic prostate cancer (mPCa). International Society of Urological Pathology recommends use of PSA as the initial immunohistochemical (IHC) marker to identify PCa. Read More

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October 2018

Effect of Tinnitus and Duration of Deafness on Sound Localization and Speech Recognition in Noise in Patients With Single-Sided Deafness.

Trends Hear 2018 Jan-Dec;22:2331216518813802

4 Department of Head and Neck Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.

Patients with single-sided deafness (SSD) often experience poor sound localization, reduced speech understanding in noise, reduced quality of life, and tinnitus. The present study aims to evaluate effects of tinnitus and duration of deafness on sound localization and speech recognition in noise by SSD subjects. Sound localization and speech recognition in noise were measured in 26 SSD and 10 normal-hearing (NH) subjects. Read More

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December 2018
4 Reads

Predictors of Unplanned Returns to the Operating Room within 30 Days in Neurosurgery: Insights from a National Surgical Registry.

World Neurosurg 2018 Nov 27. Epub 2018 Nov 27.

Mayo Clinic Neuro-Informatics Laboratory, Mayo Clinic College of Medicine and Science, Rochester, MN. Electronic address:

Background: In the modern, increasingly pay-for-performance era, unplanned ROR is gaining attention as a surgical quality metric. However, large-scale data on the appropriateness and utility of this measure in neurosurgery are scarce.

Objective: To provide a comprehensive description of all unplanned returns to the operating room (RORs) after neurosurgical procedures in a national surgical registry and identify factors associated with ROR. Read More

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November 2018
1 Read

[The use of the microbial and entomological data for the diagnostics of prescription of death coming].

Sud Med Ekspert 2018 ;61(6):52-56

Department of Public Law, Admiral S.O. Makarov State University of Maritime and Inland Shipping, Saint-Petersburg, 198035.

The objective of the present study was to demonstrate the possibility of the diagnostics of prescription of death coming (PDC) based on the results of the studies with the application of the entomological and microbiological methods. The entomological materials included larvae of two dipteran species Stearibia nigriceps (Piophilidae) and Fannia vesparia (Fanniidae) collected from bone tissue fragments and the bony bed. The detailed investigation of the succession of necrophilic insects taking place in the course of decomposition of organic matter and the development of the preimaginal stages of the dipterans made it possible to determine the duration of the period during which the corpse remained in the ambient environment. Read More

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January 2018

[The optimization of sex identification based on the craniometric information in the population of the Caucasus for the purpose of medical criminalistics personality identification].

Sud Med Ekspert 2018 ;61(6):21-24

Department of Medical and Criminalistic Identification, 'Russian Centre of Forensic Medical Expertise', Ministry of Health of the Russia, Moscow, Russia, 125284.

The authors describe the newly developed diagnostic methods for sex identification based on the step-by-step variant of the Fisher unidimensional (UDA) and multidimentional (MDA) discriminative analysis. The study is based on the materials including the craniometric data (absolute measurements n=87, indicators n=63) characteristic of the main anthropological features of the Russian Caucasian population (691 men and 376 women). Sex diagnostics using the ODA technique performed separately for each trait yielded significant, probable, and uncertain estimates in about 78, 15 and 7% cases of the total, respectively. Read More

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January 2018

Prediction of hearing recovery in sudden deafness treated with intratympanic steroids.

Acta Otorhinolaryngol Ital 2018 Oct;38(5):453-459

Department of Sensory Organs, Sapienza University of Rome, Italy.

The present study aims to obtain a probability model allowing prediction of auditory recovery in patients affected by sudden sensorineural hearing loss treated exclusively with intratympanic steroids. A monocentric retrospective chart review of 381 patients has been performed. A Probit model was used to investigate the correlation between the success of treatment (marked or total recovery according to Furuashi's criteria) and the delay between onset of disease and beginning of therapy. Read More

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October 2018

Cochlear implantation in far-advanced otosclerosis: hearing results and complications.

Acta Otorhinolaryngol Ital 2018 Oct;38(5):445-452

Department of Otorhinolaryngology and Skull Base Surgery, Pellegrin University Hospital F-33000, University of Bordeaux, France.

Severe forms of otosclerosis known as far-advanced otosclerosis (FAO) can lead to severe to profound sensorineural hearing loss and can justify cochlear implantation. Because of the pathophysiology of otosclerosis, patients implanted for FAO may experience an increased rate of complications, such as facial nerve stimulation or electrode dislocation, and may have poorer hearing outcomes than expected. This retrospective study aimed to compare cochlear implantation hearing outcomes, surgical difficulties and complications in FAO patients versus non-FAO patients. Read More

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October 2018
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Reliable manifestations of increased intracranial pressure in patients with syndromic craniosynostosis.

J Craniomaxillofac Surg 2018 Nov 12. Epub 2018 Nov 12.

Department of Plastic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

Purpose: Systematic examination of increased intracranial pressure (ICP) is important during the follow-up period after surgical repair of syndromic craniosynostosis. In these patients, postoperative progress can be unclear due to the involvement of multiple sutures and the high incidence of relapse due to the progressive nature of the disease and to genetic variability. In this study, we investigated the clinical manifestations of increased ICP in syndromic craniosynostosis patients before and after surgery. Read More

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November 2018

Pigmented villonodular synovitis occurring in the temporomandibular joint.

Auris Nasus Larynx 2018 Nov 26. Epub 2018 Nov 26.

Department of Head and Neck Surgry, Tokyo Medical and Dental University, Japan.

Objective: Pigmented villonodular synovitis occurring in the region of the temporomandibular joint is a rare disease, requiring a review of the treatment method, follow-up period.

Method: Refer to the past literature, along with a retrospective search.

Results: An excision, including the skull base bone, was performed in all cases; however, recurrence was found in one case on which fractional excision was performed. Read More

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November 2018
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Cranio-Maxillofacial and Dental Findings in Albright's Hereditary Osteodystrophy and Pseudohypoparathyroidism.

Cleft Palate Craniofac J 2018 Nov 29:1055665618814661. Epub 2018 Nov 29.

1 Oral and Maxillofacial Surgery Department, Roger Salengro Hospital, CHU Lille, University of Lille, Lille, France.

Introduction:: The clinical phenotype of pseudohypoparathyroidism (PHP) is caused by Albright's Hereditary Osteodystrophy (AHO). Often, "round face" the only facial clinical sign reported in the literature. The aim of this study was to highlight various cranio-maxillofacial clinical findings associated with AHO. Read More

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November 2018
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Postoperative cerebral venous sinus thrombosis in the setting of surgery adjacent to the major dural venous sinuses.

Authors:

J Neurosurg 2018 Oct 1:1-7. Epub 2018 Oct 1.

OBJECTIVECerebral venous sinus thrombosis (CVST) is a known complication of surgeries near the major dural venous sinuses. While the majority of CVSTs are asymptomatic, severe sinus thromboses can have devastating consequences. The objective of this study was to prospectively evaluate the true incidence and risk factors associated with postoperative CVST and comment on management strategies. Read More

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October 2018

Harvey Cushing's craniopharyngioma treatment: Part 1. Identification and clinicopathological characterization of this challenging pituitary tumor.

Authors:

J Neurosurg 2018 Oct 1:1-15. Epub 2018 Oct 1.

OBJECTIVEHarvey Cushing (1869-1939) coined the term "craniopharyngioma" (CP) in 1929 to describe a kaleidoscopic group of epithelial tumors involving the hypothalamic-pituitary axis. Throughout his career, he endured a long struggle to accurately diagnose and safely remove these complex lesions, and his resulting surgical series has never before been analyzed in depth. The authors here conduct such an analysis. Read More

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October 2018