218,529 results match your criteria Skull Base Benign Tumors


KTP-laser-assisted endoscopic management of glomus tympanicum tumors: A case series.

Ear Nose Throat J 2018 Dec;97(12):399-402

Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, 801 Welch Rd., Stanford, CA 94035, USA.

Endoscopic technology is widely used in rhinology and anterior skull base surgery, but it has been less quickly incorporated into otologic practice. The design of the instrumentation forces surgeons to work one-handed and limits depth perception. Nevertheless, endoscopy also offers wide fields of view and access to spaces that are typically difficult to visualize. Read More

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December 2018
1 Read

An Effective Simulator for Intraoral Facial Skeletal Contour Surgeries.

Ann Plast Surg 2019 Jan;82(1):99-103

Plastic and Reconstructive Surgery, Stanford University, Stanford, CA.

Background: In East Asia, intraoral facial skeletal contour surgeries (intraoral FSCSs), including reduction gonioplasty, reduction malarplasty, and genioplasty, have become increasingly popular. Nonetheless, intraoral FSCSs are technically difficult and have a steep learning curve. An effective simulator could be beneficial for intraoral FSCS training. Read More

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January 2019

From 3D imaging to 3D printing in dentistry - a practical guide.

Int J Comput Dent 2018 ;21(4):345-356

3D imaging in dentistry plays an essential part in diagnostics and treatment planning. To transform digital images into a real object that can be experienced haptically may provide new opportunities to practitioners regarding patient communication, skills training, and treatment planning. Therefore, the aim of this article is to provide a practical guide from 3D imaging to 3D printing using low-cost printers and open source software; the authors used 3D Slicer software and a Meshmixer printer, including the printer's own software. Read More

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January 2018

First two cases of craniomaxillofacial fibrous dysplasia from Nepal - case series.

Clin Cosmet Investig Dent 2018 26;10:269-274. Epub 2018 Nov 26.

Department of Oral and Maxillofacial Surgery, Chitwan Medical College and Teaching Hospital, Bharatpur-10, Chitwan, Nepal.

Fibrous dysplasia is a benign fibro-osseous disease of the bone, which is most commonly associated with congenital mutations in cAMP regulating protein Gsα coded by gene. Often it is seen involving the craniofacial skeleton and can range from an asymptomatic monostotic form to polyostotic variant involving almost all the bones of the skull, thereby leading to functional and esthetic problems. This requires a continuous monitoring of the involved region throughout the life of the patient, even after the surgical interventions. Read More

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November 2018

Proton therapy for skull base tumors: A review of clinical outcomes for chordomas and chondrosarcomas.

Head Neck 2018 Dec 7. Epub 2018 Dec 7.

University of Florida Health Proton Therapy Institute, University of Florida College of Medicine, Jacksonville, Florida.

Background: Skull base chordomas and chondrosarcomas are rare tumors traditionally treated by surgical resection and adjuvant radiation therapy (RT). We will discuss data evaluating clinical outcomes of proton therapy in the treatment of skull base chordomas and chondrosarcomas.

Methods: A literature review was performed using a MEDLINE search from January 1990 to January 2017. Read More

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December 2018

Supraglottic Squamous Cell Carcinoma: A Population-Based Study of 22,675 Cases.

Laryngoscope 2018 Dec 11. Epub 2018 Dec 11.

Department of Otolaryngology-Head and Neck Surgery, Neurological Institute of New Jersey, Newark, New Jersey, U.S.A.

Objectives/hypothesis: The authors used the Surveillance, Epidemiology, and End Results (SEER) database to analyze epidemiological features of patients presenting with supraglottic squamous cell carcinoma (SCCa) and to evaluate treatment trends and outcomes.

Methods: The SEER database was queried for patients with supraglottic SCCa from 1973 to 2013. Information on demographics; tumor size; histologic grade; American Joint Committee on Cancer (AJCC) stage; SEER local, regional, distant stage; and treatment modality were analyzed. Read More

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December 2018
1 Read

Venous thromboembolism in head and neck surgery: Risk, outcome, and burden at the national level.

Head Neck 2018 Dec 7. Epub 2018 Dec 7.

Department of Surgery, Tulane University School of Medicine, New Orleans, Louisiana.

Background: Venous thromboembolism (VTE) can complicate major surgeries. This study examines the risk and outcomes of VTE in patients who underwent head and neck surgeries.

Methods: Retrospective cross-sectional analysis utilizing the Nationwide Readmissions Database (2010-2014). Read More

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December 2018
1 Read

Multiple osteolytic lesions on the skull of a girl with Mendelian susceptibility to mycobacterial disease.

Pediatr Int 2018 Nov;60(11):1043-1044

Division of Infectious Diseases, Department of Medical Subspecialties, National Center for Child Health and Development, Setagaya, Tokyo, Japan.

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November 2018

Functional Temporomandibular Joint Reconstruction in Costochondral Grafting of Micrognathia.

Plast Reconstr Surg Glob Open 2018 Oct 2;6(10):e1925. Epub 2018 Oct 2.

Department of Plastic and Reconstructive Surgery, Osaka Medical College, Takatsuki, Japan.

Rib bone and costochondral complex grafting has been used to treat micrognathia classified as Pruzansky type III. To acquire more physiological joint movement, we reconstructed a temporomandibular joint with the glenoid fossa in addition to the mandibular ramus. The patient underwent a tracheostomy to correct her airway obstruction at 2 months of age. Read More

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October 2018
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Effects of Intraoperative Dexamethasone and Ondansetron on Postoperative Nausea and Vomiting in Microvascular Decompression Surgery: A Randomized Controlled Study.

Anesthesiol Res Pract 2018 11;2018:6297362. Epub 2018 Nov 11.

Department of Anesthesiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Background: Postoperative nausea and vomiting (PONV) is a common problem and may lead to catastrophic complications, especially in neurosurgical cases. The aim of this study was to evaluate the effects of dexamethasone and ondansetron for preventing PONV in patients who underwent microvascular decompression (MVD) surgery.

Methods: A prospective, double-blinded, randomized control trial was conducted with 54 patients who underwent MVD. Read More

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November 2018

Antineutrophil Cytoplasmic Antibody Vasculitis Causing Skull Base Inflammation and Aortitis.

Ann Indian Acad Neurol 2018 Oct-Dec;21(4):339-340

Department of Nuclear Medicine, Aster Medcity, Kochi, Kerala, India.

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December 2018

Standardization of Cranial Index Measurement in Sagittal Craniosynostosis.

J Craniofac Surg 2018 Dec 10. Epub 2018 Dec 10.

The Hospital for Sick Children.

: Cranial index is a widely used 2-dimensional measure of skull form. It has traditionally been calculated as a ratio of the maximal cranial width divided by the maximal skull length. Nevertheless, the points of maximal skull length change dramatically in sagittal craniosynostosis due to variable degrees of frontal and occipital bossing. Read More

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December 2018

Structural analysis of the frontal and parietal bones of the human skull.

J Mech Behav Biomed Mater 2018 Nov 1;90:689-701. Epub 2018 Nov 1.

Weapons and Materials Research Directorate, Army Research Laboratory, Aberdeen Proving Ground, MD 21005, United States. Electronic address:

Bone specimens were collected from the frontal and parietal bones of 4 adult, human skulls. The microstructure was characterized using microcomputed tomography (micro-CT) at about 6-μm resolution to map the change of porosity as a function of the depth, P(d), from the inner surface nearest to the brain to the outer surface nearest to the skin. A quantifiable method was developed using the measured P(d) to objectively distinguish between the three layers of the skull: the outer table, diploë , and inner table. Read More

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November 2018

Proton therapy for treatment of intracranial benign tumors in adults: A systematic review.

Cancer Treat Rev 2018 Dec 1;72:56-64. Epub 2018 Dec 1.

Radiation Oncology Department, Centre François Baclesse, Caen, France; Archade, Advanced Resource Center for Hadrontherapy in Europe, Caen, France; Normandy University, Université de Caen Basse Normandie, Caen, France; Laboratoire de Physique Corpusculaire, Caen, France.

Introduction: The depth-dose distribution of a proton beam, materialized by the Bragg peak makes it an attractive radiation modality as it reduces exposure of healthy tissues to radiations, compared with photon therapy Prominent indications, based on a long-standing experience are: intraocular melanomas, low-grade skull-base and spinal canal malignancies. However, many others potential indications are under investigations such as the benign morbid conditions that are compatible with an extended life-expectancy: low grade meningiomas, paragangliomas, pituitary adenomas, neurinomas craniopharyngioma or recurrent pleomorphic adenomas.

Materials: Given the radiation-induced risk of secondary cancer and the potential neurocognitive and functional alteration with photonic radiotherapy, we systematically analyzed the existing clinical literature about the use of proton therapy as an irradiation modality for cervical or intracranial benign tumors. Read More

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December 2018

Infant skull fractures: Accident or abuse?: Evidences from biomechanical analysis using finite element head models.

Forensic Sci Int 2018 Nov 17;294:173-182. Epub 2018 Nov 17.

Division of Neuronic Engineering, School of Technology and Health, Royal Institute of Technology - KTH, Huddinge 141 52, Sweden.

Abusive Head Trauma (AHT) is considered by some authors to be a leading cause of traumatic death in children less than two years of age and skull fractures are commonly seen in cases of suspected AHT. Today, diagnosing whether the observed fractures are caused by abuse or accidental fall is still a challenge within both the medical and the legal communities and the central question is a biomechanical question: can the described history explain the observed fractures? Finite element (FE) analysis has been shown a valuable tool for biomechanical analysis accounting for detailed head geometry, advanced material modelling, and case-specific factors (e.g. Read More

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November 2018

Pediatric alternating allergic fungal rhinosinusitis: A case report and literature review.

Int J Surg Case Rep 2018 Nov 16;54:60-62. Epub 2018 Nov 16.

Consultant ENT, Rhinology and Endoscopic Skull Base Surgery at King Fahad Specialist Hospital, Dammam, Saudi Arabia.

Objectives: to report the alternating nature of allergic fungal rhinosinusitis in children in the Eastern part of Saudi Arabia and to review the experience of King Fahad Specialist Hospital in the diagnosis and management of alternating allergic fungal rhinosinusitis in children. An 8 years old Saudi girl with alternating allergic fungal rhinosinusitis was diagnosed and managed. The patient was diagnosed to have unilateral left allergic fungal rhinosinusitis and underwent endoscopic sinus surgery and cleaning of the left sinuses from polyps, mud and mucin. Read More

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November 2018

Forces and moments in cervical spinal column segments in frontal impacts using finite element modeling and human cadaver tests.

J Mech Behav Biomed Mater 2018 Oct 2;90:681-688. Epub 2018 Oct 2.

Cemter for NeuroTrauma Research, Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, United States; Department of Orthopaedic Surgery,Medical College of Wisconsin, Milwaukee, WI, United States. Electronic address:

Experiments have been conducted using isolated tissues of the spine such as ligaments, functional units, and subaxial cervical spine columns. Forces and or moments under external loading can be obtained at the ends of these isolated/segmented preparations; however, these models require fixations at the end(s). To understand the response of the entire cervical spine without the artificial boundary/end conditions, it is necessary to use the whole body human cadaver in the experimental model. Read More

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October 2018

Preservation of venous drainage in middle fossa during combined transpetrosal approach for petroclival meningioma.

World Neurosurg 2018 Dec 6. Epub 2018 Dec 6.

Department of Neurosurgery, Tokyo Medical University, #6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.

The combined transpetrosal approach enables wide exposure around the petroclival region by lifting of the middle fossa dura and cutting of the tentorium. However, interruption of the venous drainage on the middle skull base during the transpetrosal approach has been reported to lead to temporal lobe damage.(1,2) This video (Video 1) demonstrates a microsurgical technique for the preservation of various venous drainage in the middle fossa, including the sphenobasal and sphenopetrosal veins, during the combined transpetrosal approach for treatment of a petroclival meningioma. Read More

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December 2018

Improved EEG source localization with Bayesian uncertainty modelling of unknown skull conductivity.

Neuroimage 2018 Dec 5. Epub 2018 Dec 5.

Institute for Biomagnetism and Biosignalanalysis, University of Münster, Malmedyweg 15, D-48149, Münster, Germany.

Electroencephalography (EEG) source imaging is an ill-posed inverse problem that requires accurate conductivity modelling of the head tissues, especially the skull. Unfortunately, the conductivity values are difficult to determine in vivo. In this paper, we show that the exact knowledge of the skull conductivity is not always necessary when the Bayesian approximation error (BAE) approach is exploited. Read More

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December 2018

Embryonic morphology observation and HOXC8 gene expression in crest cushions of Chinese Crested duck.

Gene 2018 Dec 7. Epub 2018 Dec 7.

Key Laboratory of Animal Genetics and Breeding and Molecular Design of Jiangsu Province, Yangzhou University, Yangzhou, Jiangsu, China. Electronic address:

The Chinese Crested duck (Fengtou duck) reappeared in China recently. Along with white feathers and a black bill and feet, the Fengtou duck has a high feather crest. This breed can be used for ornamental purposes or as a model organism; however, little is known about the genetic basis and development of its distinct morphological features. Read More

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December 2018

Nasal morbidity and quality of life after endoscopic trans-sphenoidal surgery: a single-center, prospective study.

World Neurosurg 2018 Dec 5. Epub 2018 Dec 5.

Unit of Neurosurgery, University of Brescia, Brescia, Italy.

Objective: The aim of this study was to assess nasal morbidity of endoscopic trans-sphenoidal approaches (ETA) for treatment of sellar and parasellar diseases through evaluation of quality of life (QoL) and nasal function. The impact of different ETA, according to extent and reconstruction technique, was also studied.

Methods: Patients undergoing ETA for treatment of sellar or parasellar lesions were prospectively recruited and examined preoperatively and at 6 months after surgery according to the following work-up: nasal endoscopy, rhinomanometry, acoustic rhinometry (AcR), University of Pennsylvania Smell Identification Test (UPSIT), Anterior Skull Base Nasal Inventory - 12 (ASK-12), Sino-nasal Outcome Test - 22 (SNOT-22), and Short Form Health Survey - 36 (SF-36). Read More

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December 2018

Chronic skull ostemyelitis due to Cryptococcus neoformans: first case report in an HIV-infected patient.

Braz J Infect Dis 2018 Dec 6. Epub 2018 Dec 6.

Department of Neurology, Instituto de Infectologia Emilio Ribas, São Paulo, SP, Brazil; Department of Infectious Diseases, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, HCFM-USP, São Paulo, SP, Brazil; Laboratory of Medical Investigation, Unit 49, Instituto de Medicina Tropical, Universidade de São Paulo, São Paulo, SP, Brazil.

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December 2018

Investigating the cause of late deformity following fronto-orbital remodelling for metopic synostosis using 3D CT imaging.

J Craniomaxillofac Surg 2018 Nov 16. Epub 2018 Nov 16.

Craniofacial Unit, Great Ormond Street Hospital for Children, London, UK. Electronic address:

Purpose: Late deformity/indentation is well-recognised following fronto-orbital remodelling (FOR) for metopic synostosis. We hypothesise that if damage to temporalis muscle were a contributor, the thickness of soft tissue and bone in the affected area would be reduced.

Materials And Methods: Soft tissues and bone were separately segmented and reconstructed three-dimensionally from computed tomograms of 8 patients 1. Read More

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November 2018

Skull base reconstruction with pedicled nasoseptal flap: Technique, indications, and limitations.

J Craniomaxillofac Surg 2018 Nov 16. Epub 2018 Nov 16.

Neurosurgery, Centre Hospitalier Universitaire de Liège, University of Liège, Liège, Belgium.

Endoscopic skull base surgery allows extensive tumor resection but results in large defects requiring robust dural repair. The vascularized nasal septal flap pedicled on the posterior nasal septal artery is known to have an excellent success rate for dural defect coverage. Detailed step-by-step descriptions of the harvest and placement of this flap are scarce. Read More

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November 2018

Nasal Functions in Three-Dimensional Endoscopic Skull Base Surgery.

Ann Otol Rhinol Laryngol 2018 Dec 10:3489418816723. Epub 2018 Dec 10.

2 Neurosurgery Division, Department of Neurosciences, University of Turin, Turin, Italy.

Objectives:: Endoscopic transnasal transsphenoidal surgery has become the standard procedure for the majority of skull base diseases, including sellar, parasellar, and clival pathologies. The aim of this study was the objective evaluation of nasal airflow resistances and olfactory function in 3-dimensional (3D) endoscopic transnasal transsphenoidal surgery.

Methods:: One hundred patients who underwent 3D transnasal endoscopic surgery for sellar, parasellar, and clival diseases were enrolled. Read More

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December 2018

Septal Perforation Repair Utilizing an Anterior Ethmoidal Artery Flap and Collagen Matrix.

Am J Rhinol Allergy 2018 Dec 10:1945892418816959. Epub 2018 Dec 10.

1 Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.

Background: Nasal septal perforation repair remains a challenge with no standard technique for repair recognized.

Objective: To describe the combination of an anterior ethmoidal artery flap with a collagen matrix inlay as a successful technique for nasal septal perforation repair.

Methods: A case series of consecutive patients who underwent nasal septal perforation repair with an anterior ethmoidal artery flap with an inlay collagen graft was conducted. Read More

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December 2018
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Healed impact trauma to a Neolithic cattle frontal bone: A posthuman perspective.

Int J Paleopathol 2018 Dec 3;24:197-200. Epub 2018 Dec 3.

School of Archaeology and Ancient History, University of Leicester, University Road, Leicester, LE1 7RH, UK. Electronic address:

Trauma associated with slaughter is identified occasionally archaeologically in the cranial remains of domesticated animals, with evidence for pole-axing occurring in Europe, especially from the Roman period onwards. The injury typically extends through the frontal bone and sinuses to penetrate the braincase, causing haemorrhage, loss of consciousness, brain damage, and death. Evidence for slaughter methods in the British Neolithic, however, is lacking. Read More

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December 2018
2 Reads

Epithelioid Osteoblastoma of the Temporal Bone: A Case Report.

World Neurosurg 2018 Dec 3. Epub 2018 Dec 3.

Department of Pathology, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital.

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December 2018
1 Read

Ultrasonic scalpel-assisted endoscopic endonasal surgery of infratemporal fossa: our first impressions.

World Neurosurg 2018 Dec 3. Epub 2018 Dec 3.

Division of Otorhinolaryngology, Department of Biotechnology and Life Sciences, HNS&FDRc, University of Insubria, Varese, Italy.

Background: Endoscopic endonasal transpterygoid approach is emerging as a valid option for treating selected tumors in the infratemporal fossa. Compared to traditional open approaches, the endoscopic endonasal approach (EEA) presents more difficulty in controlling bleeding and less choice in surgical instruments for endoscopic tumor dissection, which is often performed with bipolar forceps or steel dissectors.

Case Description: We describe the use of an ultrasonic scalpel device for performing endoscopic endonasal resection of two rare infratemporal fossa tumors (mature teratoma and hemangiopericytoma), which has not been reported in the literature so far. Read More

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December 2018
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Middle Meningeal Artery to Premeatal Anterior Inferior Cerebellar Artery Bypass Via Anterior Petrosectomy: An Anatomic Feasibility Study.

World Neurosurg 2018 Dec 3. Epub 2018 Dec 3.

Department of Neurological Surgery, University of California, San Francisco, California, USA; Skull Base and Cerebrovascular Laboratory, University of California, San Francisco, California, USA. Electronic address: http://skullbaselab.ucsf.edu.

Introduction: Anterior-inferior cerebellar artery (AICA) aneurysms are rare with no optimal consensus on management strategies. When the treatment requires parent artery occlusion post-operative ischemic or neuropathic, complications can occur.

Objective: To evaluate the feasibility of direct revascularization of premeatal AICA using the middle meningeal artery (MMA) as the donor through an anterior petrosectomy (APA) window. Read More

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December 2018

Whole genome variant association across 100 dogs identifies a frame shift mutation in DISHEVELLED 2 which contributes to Robinow-like syndrome in Bulldogs and related screw tail dog breeds.

PLoS Genet 2018 Dec 6;14(12):e1007850. Epub 2018 Dec 6.

Department of Population Health and Reproduction, School of Veterinary Medicine, University of California Davis, Davis, CA, United States of America.

Domestic dog breeds exhibit remarkable morphological variations that result from centuries of artificial selection and breeding. Identifying the genetic changes that contribute to these variations could provide critical insights into the molecular basis of tissue and organismal morphogenesis. Bulldogs, French Bulldogs and Boston Terriers share many morphological and disease-predisposition traits, including brachycephalic skull morphology, widely set eyes and short stature. Read More

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December 2018
7 Reads

Rediscovered identity of the scaphocephalic skull housed in the museum of the Department of Anatomy of the Medical College of the Jagiellonian University.

Folia Med Cracov 2018 ;58(3):5-10

Department of Anatomy, Jagiellonian University Medical College Kopernika 12, Kraków, Poland.

A personal data referring to the scaphoid skull housed in the Department of Anatomy of the Jagiellonian University, Medical College was established thanks to reviewing 19th century literature performed by Dr. Soficaru. We received information that the skull had belonged to an adult man who was a carpenter, born at Cracow. Read More

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January 2018
2 Reads

Utility of first positron emission tomography-computed tomography scan as a prognostic tool following treatment of sinonasal and skull base malignancies.

Head Neck 2018 Dec 6. Epub 2018 Dec 6.

Department of Otolaryngology Head and Neck Surgery and Maxillofacial Surgery, Tel-Aviv Sourasky Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

Background: The prognostic value of the first posttreatment whole body integrated positron emission tomography-computed tomography (PET/CT) scanning in patients with sinonasal/skull base malignancies is undetermined.

Methods: We retrospectively reviewed the data of all patients that underwent surgery for sinonasal/skull base malignancies in 2000-2015. The results of the pretreatment and posttreatment PET/CT findings and the clinical course were retrieved. Read More

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December 2018
2 Reads

Lack of Sphenoid Pneumatization Does Not Affect Endoscopic Endonasal Pediatric Skull Base Surgery Outcomes.

Laryngoscope 2018 Dec 5. Epub 2018 Dec 5.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania.

Objectives/hypothesis: Currently, due to the rarity of pathology, there are limited data surrounding outcomes of pediatric skull base surgery. Traditionally, surgeons have proceeded with caution when electing endonasal endoscopic transsellar/transplanum approaches to the skull base in pediatric patients due to poor sphenoid pneumatization. In this study, we review outcomes of endoscopic pediatric skull base surgery based on sphenoid pneumatization patterns. Read More

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December 2018
2 Reads

Interplay of Tumor Spread, Volume and Epstein-Barr Virus DNA in Nasopharyngeal Carcinoma: Feasibility of An Integrative Risk Stratification Scheme.

J Cancer 2018 20;9(22):4271-4278. Epub 2018 Oct 20.

Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.

To investigate the inter-correlation of tumor spread, volume and quantitative plasma Epstein-Barr virus DNA level (pEBV DNA), and to further assess the prognostic efficacy of a novel risk stratification combining anatomic, volumetric and biological features in nasopharyngeal carcinoma (NPC). One hundred and twelve patients with non-metastatic NPC were prospectively enrolled. Correlation of pEBV DNA with tumor invasiveness, lymph node (LN) metastasis, tumor volume and classification was tested by univariate and multivariate analyses. Read More

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October 2018

Three-dimensional volumetric magnetic resonance imaging (MRI) analysis of the soft palate and nasopharynx in brachycephalic and non-brachycephalic dog breeds.

J Vet Med Sci 2018 Dec 5. Epub 2018 Dec 5.

Section of Medical Imaging, Veterinary Medical Center, Chungbuk National University.

The purpose of this study was to use magnetic resonance imaging (MRI) to compare the volumes and three-dimensional configurations of the soft palate and nasopharynx in non-brachycephalic and brachycephalic dogs with different body weights, and infer which factors influence nasopharyngeal volume. This was a retrospective observational study. The brain MRI medical records of all dogs referred to the Veterinary Medical Center, Chungbuk National University, between 2013 and 2016, for evaluation of intracranial disease were reviewed. Read More

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December 2018
1 Read

Diagnostic and prognostic value of the optic nerve sheath diameter with respect to the intracranial pressure and neurological outcome of patients following hemicraniectomy.

BMC Neurol 2018 Dec 5;18(1):199. Epub 2018 Dec 5.

Department of Emergency Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, No. 88, Jiefang Road, Hangzhou City, 310009, Zhejiang Province, China.

Background: In cases showing cerebrospinal fluid (CSF) redistribution as a compensatory mechanism in acute intracranial hypertension, the optic nerve sheath diameter (ONSD) can be used to estimate intracranial pressure (ICP). However, it remains unclear whether the ONSD can be applied in patients with skull defects after a craniectomy, because the primary injury or surgical craniectomy may alter the dynamics of the CSF circulation or structure of the optical nerve sheath. This study explored the value of the ONSD in patients after a hemicraniectomy. Read More

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December 2018

Reconstruction of calvarial bone defects using poly(amino acid)/hydroxyapatite/calcium sulfate composite.

J Biomater Sci Polym Ed 2018 Dec 6:1-21. Epub 2018 Dec 6.

a College of Physical Science and Technology, Sichuan University , Chengdu 610064 , China.

The aim of this study was to evaluate the thermal properties and in vivo interface performance of poly(amino acid) (PAA) and a composite containing PAA, hydroxyapatite (HA), and calcium sulfate (CS), with respect to their suitability for skull repair. Biocompatibility was evaluated by implantation of materials into muscles of rabbits for eight weeks. Skull repair was assessed by implanting PAA, the compact PAA/HA/CS composite (c-PAA/HA/CS), and a one-side-porous PAA/HA/CS composite (p-PAA/HA/CS) into rabbit calvarial defects. Read More

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December 2018
1 Read

EFFECTS OF THE SCAN RANGE ON RADIATION DOSE IN THE COMPUTED TOMOGRAPHY COMPONENT OF ONCOLOGY POSITRON EMISSION TOMOGRAPHY/COMPUTED TOMOGRAPHY.

Radiat Prot Dosimetry 2018 Dec 1. Epub 2018 Dec 1.

Department of Radiology, Kitasato University Hospital, Kitasato, Minami-ku, Sagamihara, Kanagawa, Japan.

We performed phantom experiments to investigate radiation dose in the computed tomography component of oncology positron emission tomography/computed tomography in relation to the scan range. Computed tomography images of an anthropomorphic whole-body phantom were obtained from the head top to the feet, from the head top to the proximal thigh or from the skull base to the proximal thigh. Automatic exposure control using the posteroanterior and lateral scout images offered reasonable tube current modulation corresponding to the body thickness. Read More

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December 2018
1 Read

Anterior Cranial Vault Reconstruction With Distraction for Primary and Secondary Craniosynostosis Repair.

J Craniofac Surg 2018 Nov 30. Epub 2018 Nov 30.

Division of Plastic and Reconstructive Surgery, University of Nebraska Medical Center, Omaha, NE.

Traditional fronto-orbital advancement continues to be a useful operation for correction of craniosynostosis involving the coronal or metopic sutures. Recently, distraction osteogenesis has been used to correct a variety of cranial deformities. Studies have mostly focused on posterior vault distraction due to its simplicity and greater volume gain when compared with anterior vault distraction. Read More

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November 2018
1 Read

Using Computer-Aided Design/Computer-Aided Manufacturing for Autogenous, Split Calvarial Bone Graft-based Cranioplasty: Optimizing Reconstruction of Large, Complex Skull Defects.

J Craniofac Surg 2018 Nov 30. Epub 2018 Nov 30.

Department of Plastic and Reconstructive Surgery, Johns Hopkins Hospital, Baltimore, MD.

Background: While autologous split calvarial bone is an ideal graft material in cranioplasty, selection of a donor site can be challenging and limited in the reconstruction of complicated cranial defects. Computer-aided design and manufacturing (CAD/CAM) may improve donor-site harvest and contouring and mitigate operative complications in split calvarial bone graft-based cranioplasty for complex patients, but has not previously been studied in this unique setting.

Methods: In this study, a retrospective review of patients who presented to the institution and underwent split-calvarial bone graft-based cranioplasty using CAD/CAM to optimize reconstruction of full-thickness cranial defects ≥30 cm was performed. Read More

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November 2018
1 Read

Multiple Variations at the Base of an Adult Skull: Implications in Radiology and Skull Base Surgery.

J Craniofac Surg 2018 Nov 30. Epub 2018 Nov 30.

Melaka Manipal Medical College (Manipal Campus), Manipal Academy of Higher Education, Manipal, India.

Knowledge of variations at the base of the skull may be important for academic, anthropological, forensic, and clinical purposes, especially in computed tomography and magnetic resonance imaging and while performing safe radical surgery. This report presents multiple variations at the base of an adult Indian skull. The variations noted include the presence of foramen of Civinini bilaterally, absence of carotid canal on the left side, reduced size of foramen lacerum on the left side, presence of petro-occipital foramen bilaterally, asymmetry between the jugular fossae, and asymmetrical occipital condyles. Read More

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November 2018
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The rhinologist's role in the management of rathke's cleft cysts.

Curr Opin Otolaryngol Head Neck Surg 2018 Nov 16. Epub 2018 Nov 16.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadephia, Pennsylvania, USA.

Purpose Of Review: To review the recent literature regarding the growing role of rhinologists and otolaryngologists with neurosurgeons in the joint multidisciplinary team approach for managing patients with Rathke's cleft cysts (RCC).

Recent Findings: The transnasal endoscopic approach to the skull base has become relatively mainstream for surgical treatment of RCCs. Suprasellar lesions, especially those that are purely suprasellar, are associated with higher recurrence rates, though an extended approach may improve dissection and access and therefore aid in lesion removal. Read More

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November 2018
1 Read

Current indications for balloon sinuplasty.

Curr Opin Otolaryngol Head Neck Surg 2018 Nov 30. Epub 2018 Nov 30.

Rhinology & Endoscopic Skull Base Surgery, UCLA Department of Head & Neck Surgery, Los Angeles, California, USA.

Purpose Of Review: The purpose of the review is to evaluate the current indications and contraindications for balloon sinuplasty and review the clinical trials performed in this area.

Recent Findings: The indications for balloon sinus dilatation are somewhat similar to those for endoscopic sinus surgery. Balloon sinus ostial dilation (BSD) has been found to be most effective in the treatment of recurrent acute sinusitis (RARS) and chronic rhinosinusitis without nasal polyposis (CRSsNP) that has been refractory to medical therapy. Read More

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November 2018
2 Reads

Results and limits of posterior cranial vault expansion by osteotomy and internal distractors.

Surg Neurol Int 2018 30;9:217. Epub 2018 Oct 30.

Craniofacial Unit, Department of Pediatric Neurosurgery, Hôpital Necker-Enfants Malades, Paris, France.

Background: Expanding the posterior cranial vault has become a common procedure in the treatment of complex craniosynostosis. Several techniques are available to remodel the posterior vault. Aim of this study was to analyze the posterior vault distraction osteogenesis. Read More

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October 2018
1 Read

Impact of extra-axial cerebrospinal fluid collection in frontal morphology after surgical treatment of scaphocephaly.

Surg Neurol Int 2018 30;9:215. Epub 2018 Oct 30.

Departement of Pediatric Neurosurgery, Craniofacial Unit, Necker Enfants Malades Hospital, APHP, Paris, France.

Background: Infants with sagittal suture synostosis often present a pathologic dilatation of subarachnoid spaces. The impact of such subarachnoid spaces' enlargement in the morphology of the skull, especially on the forehead and on the surgical outcome, was analyzed.

Methods: Children less than 6 months of age undergoing a surgical correction of the scaphocephaly with Renier's H technique between 2003 and 2008 were included in the study. Read More

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October 2018
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Bones, Glands, Ears and More: The Multiple Roles of FGF10 in Craniofacial Development.

Front Genet 2018 16;9:542. Epub 2018 Nov 16.

Program in Craniofacial Biology, Departments of Orofacial Sciences and Pediatrics, Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, United States.

Members of the fibroblast growth factor (FGF) family have myriad functions during development of both non-vertebrate and vertebrate organisms. One of these family members, , is largely expressed in mesenchymal tissues and is essential for postnatal life because of its critical role in development of the craniofacial complex, as well as in lung branching. Here, we review the function of FGF10 in morphogenesis of craniofacial organs. Read More

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November 2018
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