10,985 results match your criteria Skull Base Benign Tumors


Radiologic Features of Primary Intracranial Myxomas from Skull Base: 14 Cases Report and Literature Review.

World Neurosurg 2019 Feb 7. Epub 2019 Feb 7.

Department of Neuroradiology, Tiantan Hospital, Capital Medical University, Beijing, 100050, China. Electronic address:

Backgrond: Primary intracranial myxomas (PIMs) are extremely rare benign tumors which arise from skull base. The aim of this study was to characterize the radiologic manifestation of PIMs in a series of 14 cases.

Methods: We reviewed the imaging and clinical data in 14 patients with pathologically proven PIMs. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.174DOI Listing
February 2019

Proposal for Modification of Cahan's Criteria Utilizing Molecular Genetic Analyses for Cases without Baseline Histopathology: A Unique Method Applicable to Primary Radiosurgery.

J Neurol Surg B Skull Base 2019 Feb 31;80(1):10-17. Epub 2018 May 31.

Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota, United States.

 Cahan's criteria have been utilized since 1948 to establish causality between prior radiation treatment and the development of secondary malignancy. One major criterion specifies that histological and radiographic evidence collected before and after radiation treatment must confirm separate tumor types; however, pretreatment biopsy is rarely obtained prior to radiosurgery for vestibular schwannoma and many other skull base and cranial lesions. Therefore, in these cases Cahan's criteria cannot be validly applied. Read More

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http://dx.doi.org/10.1055/s-0038-1655759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365249PMC
February 2019
1 Read

Letter to the Editor Regarding "Combined Minimally Invasive Supraciliary and Transfacial Approach for Large Tumors with Skull Base and Sinonasal Involvement".

World Neurosurg 2019 02;122:707

Department of ENT and Head and Neck Surgery, All India Institute of Medical Sciences, Ansari Nagar East, New Delhi, India.

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http://dx.doi.org/10.1016/j.wneu.2018.09.043DOI Listing
February 2019

Malignant peripheral nerve sheath tumor of the nasal cavity and nasopharynx in a child: A case report.

Medicine (Baltimore) 2019 Jan;98(4):e14223

Department of Radiology, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.

Rationale: Malignant peripheral nerve sheath tumors (MPNSTs) are rare neoplasms with only a few reported cases affecting the nasal cavity, paranasal sinuses, and anterior skull base.

Patient Concerns: A 12-year-old girl with a mass in her nose was admitted to the Department of Otorhinolaryngology of Shenzhen Children's Hospital. She had a 4-month history of progressive, unilateral right nasal obstruction, unilateral mucopurulent rhinorrhea, foul nasal odor, snoring, hyposmia, occasional epistaxis, and no headache, no facial numbness, without eye swelling and vision loss. Read More

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http://dx.doi.org/10.1097/MD.0000000000014223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358413PMC
January 2019
3 Reads
5.723 Impact Factor

Grading of MRI-detected skull-base invasion in nasopharyngeal carcinoma with skull-base invasion after intensity-modulated radiotherapy.

Radiat Oncol 2019 Jan 17;14(1):10. Epub 2019 Jan 17.

Department of Radiation Oncology, Zhejiang Cancer Hospital, Hangzhou, 310022, China.

Background: The aim of this study is to evaluate the prognostic value of grading MRI-detected skull-base invasion in nasopharyngeal carcinoma (NPC) with skull-base invasion after intensity-modulated radiotherapy (IMRT).

Methods: This study is a retrospective chart review of 469 non-metastatic NPC patients with skull-base invasion. Patients were classified as extensive skull-base invasion (ESBI) group and limited skull-base invasion (LSBI) group. Read More

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http://dx.doi.org/10.1186/s13014-019-1214-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335845PMC
January 2019
1 Read

Long-term impact of pediatric endoscopic endonasal skull base surgery on midface growth.

J Neurosurg Pediatr 2019 Jan 11:1-8. Epub 2019 Jan 11.

Departments of1Plastic Surgery.

OBJECTIVECranial base development plays a large role in anterior and vertical maxillary growth through 7 years of age, and the effect of early endonasal cranial base surgery on midface growth is unknown. The authors present their experience with pediatric endoscopic endonasal surgery (EES) and long-term midface growth.METHODSThis is a retrospective review of cases where EES was performed from 2000 to 2016. Read More

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http://dx.doi.org/10.3171/2018.8.PEDS18183DOI Listing
January 2019
2 Reads

Rapidly Growing and Asymptomatic Skull Base Lesion.

J Craniofac Surg 2019 Jan 10. Epub 2019 Jan 10.

Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas.

Trochlear schwannomas typically present with diplopia and are extremely rare benign intracranial neoplasms that require the combined expertise of neurotologists and neurosurgeons for surgical excision. A combined petrosal approach offers a surgical route for removal of growing and/or symptomatic tumors. A study of a trochlear nerve schwannoma that demonstrated rapid growth but was otherwise asymptomatic was presented in this study. Read More

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http://dx.doi.org/10.1097/SCS.0000000000005153DOI Listing
January 2019
1 Read

Skull base angiomatous leiomyoma: a case report and review of literature.

Br J Neurosurg 2019 Jan 12:1-3. Epub 2019 Jan 12.

b Department of Neurosurgery , Royal Hallamshire Hospital , Sheffield , UK.

Leiomyomas, benign neoplasms of mesenchymal origin, are common in gastrointestinal and genitourinary tracts. They are comprised of well-differentiated smooth muscle cells with few mitotic figures. Leiomyomas should not exhibit metastatic potential, though metastasis has been reported. Read More

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http://dx.doi.org/10.1080/02688697.2018.1555636DOI Listing
January 2019
4 Reads

Sino-orbital desmoid tumor in a pediatric patient - Case report with review of literature.

Orbit 2018 Dec 27:1-9. Epub 2018 Dec 27.

e Department of Pediatric Oncology , National University Health System , Singapore , Singapore.

We report a case of a 2-year-old female who presented with bilateral progressive proptosis, visual loss, nasal obstruction, and breathing difficulty. Magnetic resonance imaging revealed a large sino-orbital mass that was extending to the orbital apex and skull base. An initial diagnosis of rhabdomyosarcoma was made elsewhere on the basis of the presence of round and spindle cell tumor. Read More

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http://dx.doi.org/10.1080/01676830.2018.1556306DOI Listing
December 2018
2 Reads

Characteristics and management of sinonasal paragangliomas: a systematic review.

Int Forum Allergy Rhinol 2018 Dec 20. Epub 2018 Dec 20.

Department of Otolaryngology-Head and Neck Surgery, Rutgers New Jersey Medical School, Newark, NJ.

Background: Paragangliomas of the nasal cavity and paranasal sinuses, although exceedingly rare, can exhibit frequent and aggressive recurrences. Our objective was to evaluate tumor characteristics, clinical course, management, and associated complications of sinonasal paragangliomas METHODS: A systematic review of the literature was performed utilizing the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines, searching for sinonasal paraganglioma. Studies meeting inclusion criteria were assessed for level of evidence. Read More

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http://doi.wiley.com/10.1002/alr.22261
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http://dx.doi.org/10.1002/alr.22261DOI Listing
December 2018
11 Reads
2.371 Impact Factor

Immature Teratoma of Nasal Septum: A Case Report.

Iran J Otorhinolaryngol 2018 Nov;30(101):355-359

Department of Otorhinolaryngology, Topiwala National Medical College and BYL Nair Hospital, Mumbai, Maharashtra, India.

Introduction: Teratomas are neoplastic tumors derived from totipotent germ cells containing a wide assortment of tissues originating from all three germ cell layers. Teratomas can be mature or immature depending on the presence of immature tissues; typically neuroepithelial tissue. Immature teratomas can be oncologically benign or malignant, and can be divided into three grades with increasingly aggressive biological behavior. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291815PMC
November 2018

[The surgical management of upper parapharyngeal regions].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1804-1809

Department of Otorhinolaryngology, the First Affiliated Hospital, Bengbu Medical College, Bengbu, 233004, China.

To find proper the surgical approval and evaluate clinical efficacy to treat the tumor of upper parapharyngeal space involving the base of skull and intracranial skull. The data of 9 cases from June 2013 and June 2018 were analyzed retrospectively including schwannoma in 6 cases, pleomorphic adenoma in 2 cases and hemangioma in 1 case. All cases received preoperative high resolution CT and MRI, some cases also did the DSA examination. Read More

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http://www.cnki.net/kcms/doi/10.13201/j.issn.1001-1781.2018.
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http://dx.doi.org/10.13201/j.issn.1001-1781.2018.23.009DOI Listing
December 2018
11 Reads

[Application of image-guided system in endoscopic sinus and skull base surgery].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(24):1856-1859

Department of Otorhinolaryngology Head and Neck Surgery, Huadong Hospital, Fudan University, Shanghai, 200040,China.

To evaluate the applicative value of image-guided system in endoscopic sinus and skull base surgeries. A total of 103 endoscopic surgical procedures were performed.All these procedures were conducted with the utilization of image-guided system, among which there were 92 cases of sinonasal-skull base surgery(including nasal sinuses resection of benign and malignant tumors involving skull base lesions, the cumulative orbital lesion resection of nasal sinus lesions, etc. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2018.24.003DOI Listing
December 2018
2 Reads

Surgical management and prognostic factors for primary intracranial myxoma: a single-institute experience with a systematic review.

J Neurosurg 2018 Nov 1:1-11. Epub 2018 Nov 1.

1Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University; and.

OBJECTIVEPrimary intracranial myxomas (PICMs) are extremely rare neoplasms, and their management and prognostic factors remain ambiguous. The authors aimed to elaborate the radiological features, evaluate the risk factors for progression-free survival (PFS), and propose a treatment protocol based on pooled data from cases treated at their institute and those found in the literature.METHODSClinical data from all cases of PICMs treated at the authors' institute and those cases reported in the English-language literature between 1987 and December 2017 were reviewed. Read More

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http://dx.doi.org/10.3171/2018.6.JNS181132DOI Listing
November 2018
1 Read
3.737 Impact Factor

Proton therapy for treatment of intracranial benign tumors in adults: A systematic review.

Cancer Treat Rev 2019 Jan 1;72:56-64. Epub 2018 Dec 1.

Radiation Oncology Department, Centre François Baclesse, Caen, France; Archade, Advanced Resource Center for Hadrontherapy in Europe, Caen, France; Normandy University, Université de Caen Basse Normandie, Caen, France; Laboratoire de Physique Corpusculaire, Caen, France.

Introduction: The depth-dose distribution of a proton beam, materialized by the Bragg peak makes it an attractive radiation modality as it reduces exposure of healthy tissues to radiations, compared with photon therapy Prominent indications, based on a long-standing experience are: intraocular melanomas, low-grade skull-base and spinal canal malignancies. However, many others potential indications are under investigations such as the benign morbid conditions that are compatible with an extended life-expectancy: low grade meningiomas, paragangliomas, pituitary adenomas, neurinomas craniopharyngioma or recurrent pleomorphic adenomas.

Materials: Given the radiation-induced risk of secondary cancer and the potential neurocognitive and functional alteration with photonic radiotherapy, we systematically analyzed the existing clinical literature about the use of proton therapy as an irradiation modality for cervical or intracranial benign tumors. Read More

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http://dx.doi.org/10.1016/j.ctrv.2018.11.004DOI Listing
January 2019
2 Reads

Surgical management and long-term outcomes of intracranial giant cell tumors: a single-institution experience with a systematic review.

J Neurosurg 2018 Oct 1:1-11. Epub 2018 Oct 1.

1Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing; and.

OBJECTIVEIntracranial giant cell tumors (GCTs) are extremely rare neoplasms with dismal survival and recurrence rates. The authors aimed to confirm independent adverse factors for progression-free survival (PFS) and to propose an optimal treatment algorithm.METHODSThe authors reviewed the clinical data of 43 cases of intracranial GCTs in their series. Read More

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http://dx.doi.org/10.3171/2018.4.JNS1849DOI Listing
October 2018
4 Reads
3.737 Impact Factor

Epidemiology of meningiomas. A nationwide study of surgically treated tumours on French medico-administrative data.

Cancer Epidemiol 2019 Feb 24;58:63-70. Epub 2018 Nov 24.

Department of Medical Information, Georges Pompidou European Hospital, 75015, Paris, France.

Background: To describe the epidemiology of surgically treated meningiomas and compare the results with previously published studies.

Methods: We processed the French medico-administrative national hospital discharge summary database, Programme de Médicalisation des Systèmes d'Information (PMSI) using an algorithm combining the type of surgical procedure and codes from the International Classification of Diseases to retrieve appropriate cases of meningiomas operated between 2008 and 2016.

Results: This nationwide study found 25,737 cases of operated meningiomas. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18777821183022
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http://dx.doi.org/10.1016/j.canep.2018.11.004DOI Listing
February 2019
6 Reads

Treatment outcomes of proton or carbon ion therapy for skull base chordoma: a retrospective study.

Radiat Oncol 2018 Nov 26;13(1):232. Epub 2018 Nov 26.

Department of Radiology, Hyogo Ion Beam Medical Center, Tatsuno, Hyogo, Japan.

Background: The usefulness of particle therapy for skull base chordoma has not been established. The aim of this retrospective study was to analyse the treatment outcomes of proton therapy (PT) and carbon ion therapy (CIT) in patients with skull base chordoma at a single institution.

Methods: All patients who underwent PT or CIT with curative intent between 2003 and 2014 at Hyogo Ion Beam Medical Center were included in this study. Read More

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https://ro-journal.biomedcentral.com/articles/10.1186/s13014
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http://dx.doi.org/10.1186/s13014-018-1173-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260885PMC
November 2018
5 Reads

Massive aneurysmal bone cyst of the skull base treated with denosumab.

Head Neck 2018 Dec 26;40(12):E107-E113. Epub 2018 Nov 26.

Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Background: Aneurysmal bone cysts are rare, benign expansile tumors most commonly involving long bones and vertebrae in patients younger than age 20. Skull base involvement is rare. Aneurysmal bone cysts shares radiological and histological features with other bone tumors, posing a diagnostic challenge. Read More

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http://doi.wiley.com/10.1002/hed.25438
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http://dx.doi.org/10.1002/hed.25438DOI Listing
December 2018
13 Reads

Letter to the Editor Regarding "Comparison of the Effectiveness of Radiotherapy with Photons and Particles for Chordoma After Surgery: A Meta-Analysis".

Authors:
Ensiyeh Jenabi

World Neurosurg 2018 12;120:603

Pediatric Developmental Disorders Research Center, Hamadan University of Medical Sciences, Hamadan, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.wneu.2018.08.248DOI Listing
December 2018

Management of Vestibular Schwannomas for the Radiologist.

Neuroimaging Clin N Am 2019 Feb 31;29(1):173-182. Epub 2018 Oct 31.

Otolaryngology-Head and Neck Surgery, Vagelos College of Physicians & Surgeons, NewYork-Presbyterian/Columbia University Irving Medical Center, 180 Fort Washington Avenue, New York, NY 10032, USA. Electronic address:

Vestibular schwannomas are the most common tumor of the cerebellopontine angle. The history of their management has driven advances in imaging, lateral skull base surgery, as well as radiosurgery. With these advances, a shift has occurred from life-saving treatment for late-stage disease to quality of life focused management of smaller tumors. Read More

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http://dx.doi.org/10.1016/j.nic.2018.09.003DOI Listing
February 2019
10 Reads

Temporal Bone Tumors: An Imaging Update.

Neuroimaging Clin N Am 2019 Feb;29(1):145-172

Department of Radiology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA.

In their variety, temporal bone tumors mirror the complexity of the structure from which they arise. They include more familiar lesions, such as vestibular schwannomas and paragangliomas, and also rarer neoplasms, such as nonvestibular schwannomas, sarcomas, giant cell tumors, Schneiderian papillomas, and endolymphatic sac tumors. Diagnostic imaging is invaluable in evaluating such lesions because they are typically challenging to access surgically and monitor clinically. Read More

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http://dx.doi.org/10.1016/j.nic.2018.09.007DOI Listing
February 2019
15 Reads

Gamma Knife Management of Skull Base Chordomas: Is it a Choice?

Asian J Neurosurg 2018 Oct-Dec;13(4):1037-1041

Department of Neurosurgery, Mansoura University Hospital, Mansoura, International Medical Center, Cairo, Egypt.

Background: Skull base chordomas are locally invasive tumors which able to extend in different directions with skull base invasion. Although they are histologically benign, they have invasive nature makes total resection virtually impossible to achieve in most cases and this lead to residual tumors after surgery. To decrease postoperative surgical resection morbidity of these tumors, gamma knife radiosurgery (GKRS) was performed as alternative management for these residual chordomas to evaluate its safety and efficacy. Read More

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http://dx.doi.org/10.4103/ajns.AJNS_61_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208200PMC
November 2018
7 Reads

Gamma Knife radiosurgery for glomus tumors: Long-term results in a series of 30 patients.

Head Neck 2018 Dec 20;40(12):2677-2684. Epub 2018 Nov 20.

Department of Neurosurgery and Gamma Knife Radiosurgery, I.R.C.C.S. San Raffaele Scientific Institute, Vita-Salute University, Milan, Italy.

Background: Glomus tumors are rare and benign hypervascular tumors. Surgery represented the mainstay of their treatment, even if it has been associated with high morbidity and mortality rates. Recently, the treatment shifted to a multimodal approach and Gamma Knife radiosurgery represents one of the treatment options. Read More

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http://dx.doi.org/10.1002/hed.25517DOI Listing
December 2018
21 Reads

Retrosigmoid Craniotomy for Resection of an Epidermoid Cyst of the Posterior Fossa.

J Neurol Surg B Skull Base 2018 Dec 25;79(Suppl 5):S411-S412. Epub 2018 Sep 25.

Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, Utah, United States.

This video illustrates the case of a 51-year-old woman who presented with sudden-onset headache, vertigo, and nausea. Imaging revealed an epidermoid cyst of the posterior fossa with mass effect upon the brainstem and displacement of the basilar artery. This lesion was approached using a left-sided keyhole retrosigmoid craniotomy with monitoring of the cranial nerves. Read More

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http://dx.doi.org/10.1055/s-0038-1669980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240416PMC
December 2018
2 Reads

Middle Ear Osteoma Causing Mixed Hearing Loss: A Case Report.

J Int Adv Otol 2018 Dec;14(3):493-496

Department of Otolaryngology Head and Neck Surgery, and Skull Base Surgery, Centre Hospitalier Universitaire (CHU) de Bordeaux, Bordeaux, France.

Osteomas of the middle ear are rare benign tumors. Their consequences and symptoms are due to their specific location, such as the promontory or the epitympanum and their contact with the facial nerve, the semicircular canal, the ossicles, and the oval or round windows. We report a very unusual case of middle ear osteoma (MEO) in a 23-year-old male patient causing a right mixed hearing loss by contacting and overwhelming the incus and stapes. Read More

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http://www.advancedotology.org/eng/makale/1273/84/Full-Text
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http://dx.doi.org/10.5152/iao.2018.5265DOI Listing
December 2018
7 Reads

[The application of the hidrogel-based medicinal compositions for the targeted delivery of medications in rhino- and otosurgery].

Vestn Otorinolaringol 2018 ;83(5):68-70

Research and Clinical Centre of Otorhinolaryngology, Russian Medico-Biological Agency, Moscow, Russia.

The objective of the present study was the analysis of the application of the hydrogel-based medicinal compositions for the treatment of the patients presenting with pathological changes in the nasal cavity and paranasal sinuses during the postoperative period. A total of 25 patients at the age from 18 to 60 years with the diseases of the nasal cavity and paranasal sinuses were available for the examination including 12 ones with polypous polysinusitis and 13 patients having benign neoplasms in the nasal cavity, paranasal sinuses, and the base of the skull. All these patients underwent endoscopic endonasal polysinusotomy. Read More

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http://dx.doi.org/10.17116/otorino20188305168DOI Listing
January 2018
18 Reads

Endoscopic Endonasal Repair of a Persistent Craniopharyngeal Canal and Sphenoid Meningoencephalocele: Case Report and Review of Literature.

World Neurosurg 2019 Feb 1;122:196-202. Epub 2018 Nov 1.

Department of Pathology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.

Background: A persistent craniopharyngeal canal (PCC) is a rare cause of cerebrospinal fluid rhinorrhea in children. The condition often coexists with other midline facial defects, such as cleft palate. Children with PCC may also have pituitary dysfunction or neoplasms, such as craniopharyngiomas within the canal. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183243
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http://dx.doi.org/10.1016/j.wneu.2018.10.138DOI Listing
February 2019
11 Reads

Poorly Differentiated Primary Carcinoma of the Middle Ear on 18F-FDG PET/CT.

Clin Nucl Med 2019 Jan;44(1):e43-e45

From the Departments of Radiology, and.

Primary carcinoma of the middle ear is extremely rare. A 41-year-old woman with a history of skull base osteomyelitis and chronic suppurative right otitis media presented with 1 month of right-sided facial droop, tearing, and headaches. Initial head CT revealed bony destruction and soft tissue opacification involving the right middle ear. Read More

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http://dx.doi.org/10.1097/RLU.0000000000002361DOI Listing
January 2019
2 Reads

Myeloid Sarcoma of the Paranasal Sinuses in a Patient with Acute Myeloid Leukemia.

Tohoku J Exp Med 2018 10;246(2):141-146

Department of Otolaryngology-Head and Neck Surgery, Tohoku University School of Medicine.

Myeloid sarcoma (MS) is an uncommon extramedullary malignant tumor, and often represents a subgroup of acute myeloid leukemia (AML). MS of paranasal sinus origin is extremely rare. We report an uncommon case of sinonasal MS associated with AML, who was successfully treated with hematopoietic stem-cell transplantation. Read More

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https://www.jstage.jst.go.jp/article/tjem/246/2/246_141/_art
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http://dx.doi.org/10.1620/tjem.246.141DOI Listing
October 2018
12 Reads

Trans-Frontal Five-Fluorouracil (TraFFF): a novel technique for the application of adjuvant topical chemotherapeutic agents in sinonasal adenocarcinoma.

BMJ Case Rep 2018 Oct 24;2018. Epub 2018 Oct 24.

Otolaryngology, Head and Neck Surgery, Westmead Hospital, Sydney, NSW, Australia.

Sinonasal adenocarcinoma has traditionally been treated with surgery (craniofacial or endoscopic) and adjuvant radiotherapy. Two large series have demonstrated favourable 5-year survival using surgery with adjuvant topical chemotherapy applied repeatedly over several weeks. The authors describe a novel, transnasal application of topical 5-fluorouracil. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22623
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http://dx.doi.org/10.1136/bcr-2018-226234DOI Listing
October 2018
13 Reads

Benign notochordal cell tumour: clinicopathology and molecular profiling of 13 cases.

J Clin Pathol 2019 Jan 24;72(1):66-74. Epub 2018 Oct 24.

Department of Neuropathology, Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, China National Clinical Research Center for Neurological Diseases (NCRC-ND), Center of Brain Tumor, Beijing Institute for Brain Disorders, Beijing Key Laboratory of Brain Tumor, Beijing, China

Aims: To study the clinicopathological and molecular features of benign notochordal cell tumours (BNCTs) and their differential diagnosis from chordoma.

Methods: 13 cases of BNCT were investigated. The genome-wide copy number imbalances were performed using Oncoscan CNV array in three cases and fluorescence in situ hybridisation (FISH) detection of epidermal growth factor receptor (EGFR)/chromosome 7 enumeration probe (CEP7), LSI1p36/1q21, LSI19p13/19q13, CEP3/CEP12 and Telvysion 6 P was performed in 13 cases. Read More

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http://dx.doi.org/10.1136/jclinpath-2018-205441DOI Listing
January 2019
3 Reads

[Application of three-dimensional printing technology in the surgical treatment of nasal skull base tumor].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Oct;53(10):780-784

Department of Otorhinolaryngology Head and Neck Surgery, Tianjin HuanHu hospital, Tianjin 300350, China.

To explore the application value of three dimensional (3D) printing technique in the surgical treatment of nasal skull base tumor. Seven patients with complicated skull base tumors admitted in Department of Otorhinolaryngology Head and Neck Surgery and Department of Neurosurgery of Tianjin HuanHu Hospital from Mar. 2017 to Feb. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1673-0860.2018.10.012DOI Listing
October 2018
8 Reads

Parapharyngeal Space Tumor: Submandibular Approach Without Mandibulotomy.

J Maxillofac Oral Surg 2018 Dec 27;17(4):616-624. Epub 2018 Jun 27.

Department of Head and Neck Surgery, Instituto Nacional de Cancerologia, Av. San Fernando #22, Col. Sección XVI, Tlalpan, 14080 Mexico, D.F. Mexico.

Introduction: Among all head and neck tumors, only 0.5% occur in the parapharyngeal space and 80% are benign tumors. Surgery is the cornerstone of treatment. Read More

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http://link.springer.com/10.1007/s12663-018-1133-0
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http://dx.doi.org/10.1007/s12663-018-1133-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181834PMC
December 2018
10 Reads

Atypical Presentation of PHACE Syndrome: Hidden Facial Hemangioma.

Pediatr Neurosurg 2018 18;53(6):421-426. Epub 2018 Oct 18.

Interventional Neuroradiology, Hospital Pequeno Principe, Curitiba, Brazil.

PHACE(S) syndrome is a neurocutaneous syndrome with a wide array of presentations. The most known and present trait is facial hemangioma > 5 cm. The name is an acronym for Posterior fossa malformations, infantile Hemangiomas, Arterial anomalies, aortic Coarctation, Eye abnormalities, and middle-line malformations of the Sternum. Read More

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https://www.karger.com/Article/FullText/493491
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http://dx.doi.org/10.1159/000493491DOI Listing
January 2019
17 Reads

Outcomes of Open vs Endoscopic Skull Base Surgery in Patients 70 Years or Older.

JAMA Otolaryngol Head Neck Surg 2018 Oct;144(10):923-928

Department of Otolaryngology-Head and Neck Surgery, University of North Carolina at Chapel Hill.

Importance: The use of skull base surgery in patients 70 years or older is increasing, but its safety in this age group has not been evaluated to date.

Objectives: To describe outcomes in a cohort of patients 70 years or older undergoing skull base surgery and to evaluate whether age, type of disease process, and approach (endoscopic vs traditional open surgery) are associated with increased intraoperative and postoperative complications in this population.

Design, Setting, And Participants: This retrospective cohort study analyzed a population-based sample of 219 patients 70 years or older from a database of 1720 patients who underwent skull base surgery at University of North Carolina Hospitals, Chapel Hill, a tertiary referral center, between October 2007 and June 2017. Read More

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http://dx.doi.org/10.1001/jamaoto.2018.1948DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233820PMC
October 2018
2 Reads

Intracranial grade I meningiomas: Confrontation between histological examination and magnetic resonance imaging.

Tunis Med 2018 Jan;96(1):18-21

Introduction: Meningiomas are tumors derived from arachnoid cells. More than 90% of cases have a benign clinical course and are classified as grade I according to the World Health Organization. A confrontation between radiologic findings and pathological examination is necessary to predict the grading of meningiomas. Read More

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January 2018
11 Reads

Impact of venous thromboembolism during admission for meningioma surgery on hospital charges and postoperative complications.

J Clin Neurosci 2019 Jan 9;59:218-223. Epub 2018 Oct 9.

Department of Neurological Surgery, Center for Skull Base and Pituitary Surgery, Neurological Institute of New Jersey, Rutgers New Jersey Medical School, Newark, NJ, USA; Department of Otolaryngology - Head and Neck Surgery, Rutgers New Jersey Medical School, Newark, NJ, USA. Electronic address:

Surgical resection of meningiomas has been associated with high rates of venous thromboembolic events (VTE) as compared with all other intracranial tumors. There is a paucity of data regarding the clinical complications and comorbidities associated with this cohort yet the underlying pathophysiological mechanism for this tumor-specific finding remains unclear. Our goal was to determine the various impacts of VTE on meningioma surgery in a large cohort of inpatient admissions. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09675868183017
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http://dx.doi.org/10.1016/j.jocn.2018.09.018DOI Listing
January 2019
3 Reads

Meckel Cave Epidermoid Cyst Presenting as Multiple Cranial Nerve Deficits Due to Indirect Tumoral Compression of the Cavernous Sinus: A Case Report and Literature Review.

World Neurosurg 2019 Jan 9;121:88-94. Epub 2018 Oct 9.

Section of Neurosurgery, Carilion Clinic, Roanoke, Virginia, USA; Virginia Tech Carilion School of Medicine, Roanoke, Virginia, USA; Virginia Tech School of Neuroscience, Blacksburg, Virginia, USA. Electronic address:

Background: Epidermoid cysts in Meckel cave are exceedingly rare. Since 1971, only 17 cases have been reported in the literature, with most patients presenting with trigeminal hypesthesia. However, outgrowth of these lesions from Meckel cave can rarely lead to compression of the proximate cavernous sinus and the neurovascular structures contained within. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.09.206DOI Listing
January 2019
4 Reads

Vidian Nerve Schwannoma: A Rare Skull-Base Neoplasm Presenting with Ocular Manifestations: A Case Report and Literature Review.

Perm J 2018 ;22

Surgeon in the Department of Otolaryngology-Head and Neck Surgery at the Oakland Medical Center in CA

Introduction: Vidian nerve schwannomas are exceedingly rare, with only 7 cases reported since 2006. Patients presenting with ocular symptoms have been reported in only 1 case.

Case Presentation: A 54-year-old woman presented with a 3-month history of right periorbital pressure, third cranial nerve palsy, and visual field defect. Read More

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http://www.thepermanentejournal.org/issues/2018/fall/6868-vi
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http://dx.doi.org/10.7812/TPP/18-021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172031PMC
January 2019
8 Reads

[Analysis and surgical treatment of 72 cases of parapharyngeal space tumors].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Sep;32(17):1343-1347

Department of Otorhinolaryngology Head and Neck Surgery, the First Hospital of Peking University,Beijing,100034,China.

To summarize and analyze the clinical features, diagnosis methods, surgical approaches and treatment outcomes of patients with parapharygeal space tumors.A retrospective review of 72 cases with parapharygeal space tumors treated from March 1994 to June 2017 was performed. The data on presentation, surgical approach, histological diagnosis and postoperative complications were reviewed. Read More

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http://www.cnki.net/kcms/doi/10.13201/j.issn.1001-1781.2018.
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http://dx.doi.org/10.13201/j.issn.1001-1781.2018.17.012DOI Listing
September 2018
4 Reads

Preoperative embolization of skull base meningiomas: A systematic review.

J Clin Neurosci 2019 Jan 29;59:259-264. Epub 2018 Sep 29.

Department of Neurological Surgery, University of Virginia, Charlottesville, VA, United States.

Neoadjuvant endovascular embolization of skull base meningiomas may facilitate surgical resection, thereby potentially decreasing operative morbidity. However, due to variation in the reported efficacy and complication rates, the utility of embolization remains incompletely defined. The aim of this systematic review is to assess the outcomes of preoperative embolization for skull base meningiomas. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09675868183052
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http://dx.doi.org/10.1016/j.jocn.2018.06.022DOI Listing
January 2019
17 Reads

Three-Dimensional Volume Imaging to Increase the Accuracy of Surgical Management in a Case of Recurrent Chordoma of the Clivus.

Am J Case Rep 2018 Oct 2;19:1168-1174. Epub 2018 Oct 2.

Department of Orthodontics and Radiology, School of Dentistry, University City of São Paulo (UNICID), São Paulo, SP, Brazil.

BACKGROUND The clivus is a depression in the anterior occipital bone of the skull base, posterior to the dorsum sellae, at the junction with the sphenoid bone. Chordoma is a rare tumor arising from embryonic remnants of the notochord and can be locally aggressive with a tendency to recur. The optimal management of this rare tumor remains controversial. Read More

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http://dx.doi.org/10.12659/AJCR.911592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180943PMC
October 2018
7 Reads

Intracranial Dural Parafalcine Chondroma: Case Report and Systematic Review of the Literature.

World Neurosurg 2019 Feb 29;122:1-7. Epub 2018 Sep 29.

Division of Neurosurgery, Hamilton General Hospital, McMaster University, Hamilton, Ontario, Canada.

Intracranial chondromas are rare, benign neoplasms representing only 0.2%-0.3% of neoplastic intracranial lesions. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.09.169DOI Listing
February 2019
6 Reads

[Magnetic resonance as initial screening diagnosis of secondary involvement of central nervous system in NHL diffuse large B cell lymphoma]

Rev Fac Cien Med Univ Nac Cordoba 2018 06 10;75(2):67-71. Epub 2018 Jun 10.

Hospital de Clínicas. Universidad de la República, Montevideo, Uruguay.

Background: Background: Central Nervous System (CNS) relapse in Diffuse Large B-cell Lymphoma occurs mostly 6-8 months after disease onset. This has led to propose that CNS infiltration is an early event in the evolution of the disease. We intend to evaluate the role of magnetic resonance imaging (MR) at diagnosis to detect early SNC compromise. Read More

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http://dx.doi.org/10.31053/1853.0605.v75.n2.17517DOI Listing
June 2018
3 Reads

Anterior Cranial Fossa Calcifying Pseudoneoplasm of the Neuroaxis-Diagnosis Using a Transblepharoplasty Approach.

J Neurol Surg Rep 2018 Jul 27;79(3):e75-e78. Epub 2018 Sep 27.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Johns Hopkins University, Baltimore, Maryland, United States.

Calcifying pseudoneoplasms of the neuroaxis (CAPNON) are rare, benign tumors of unknown histogenesis. CAPNON generally are found intracranially or within the spinal column in symptomatic patients. We present the case of an asymptomatic patient with an incidentally discovered right anterior cranial fossa mass with extension through the posterior and anterior table of the right frontal sinus and right superior orbital roof. Read More

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http://dx.doi.org/10.1055/s-0038-1673392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160293PMC
July 2018
3 Reads

Low-Grade Papillary Schneiderian Carcinoma of the Sinonasal Cavity and Temporal Bone.

Ann Otol Rhinol Laryngol 2018 Dec 29;127(12):974-977. Epub 2018 Sep 29.

1 Division of Head and Neck Surgery & Communication Sciences, Department of Surgery, Duke University Medical Center, Durham, NC, USA.

Objectives:: The aim of this study was to further characterize a newly described neoplasm, low-grade papillary Schneiderian carcinoma, occurring simultaneously in the sinonasal cavity and mastoid. Additionally, the authors review the only 2 similar cases within the literature and describe the common clinical features, radiographic findings, and pathologic characteristics of this exceptionally rare disease process.

Methods:: Chart review for single patient, review of literature. Read More

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http://journals.sagepub.com/doi/10.1177/0003489418803391
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http://dx.doi.org/10.1177/0003489418803391DOI Listing
December 2018
8 Reads

Transsphenoidal Removal of Recurrent Osteoid Osteoma of Clivus.

World Neurosurg 2018 Dec 26;120:506-508. Epub 2018 Sep 26.

Department of Neurosurgery, University of Tuebingen, Tuebingen, Germany.

Background: An osteoid osteoma (OO) is a benign bone neoplasm that typically occurs in the long bone diaphysis. We found only 8 cases of OOs of the skull base in the literature, and none of them were located in the clivus.

Case Description: A 44-year-old female patient with a history of 2 previous transsphenoidal surgeries with partial removal of an OO of the clivus at another hospital, 11 and 4 years ago, presented to our department with recurrent progressive left-sided headache and facial pain over the past 6 months, which were aggravated at night. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183217
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http://dx.doi.org/10.1016/j.wneu.2018.09.133DOI Listing
December 2018
11 Reads

Endoscopic Endonasal Transclival Approach to Tumors of the Clivus and Anterior Region of the Posterior Cranial Fossa (Results of Surgical Treatment of 136 Patients).

World Neurosurg 2019 Jan 24;121:e246-e261. Epub 2018 Sep 24.

Department of Spine Pathology, N.N. Priorov Central Institute of Traumatology and Orthopedics, Moscow, Russia.

Introduction: With the introduction into the neurosurgical practice of minimally invasive methods using endoscopic techniques, it became possible to effectively remove hard-to-reach tumors, including central tumors of the anterior region of the posterior cranial fossa.

Objective: To analyze the results of surgical treatment of patients with various centrally located tumors of the base of the skull that extend into the anterior region of the posterior cranial fossa using the endoscopic endonasal transclival approach.

Methods: The personal surgical experience of the first author is 136 patients with various tumors (e. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.09.090DOI Listing
January 2019
11 Reads

Predicting Readmission and Reoperation for Benign Cranial Nerve Neoplasms: A Nationwide Analysis.

World Neurosurg 2019 Jan 25;121:e223-e229. Epub 2018 Sep 25.

Computational Neurosciences Outcomes Center, Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; Center for Skull Base and Pituitary Surgery, Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. Electronic address:

Objective: Readmission and reoperation are risks in the resection of benign cranial nerve tumors (BCNTs). This report analyzes the impact of patient-level and surgical factors on these adverse outcomes.

Methods: This retrospective cohort review comprised patients with a diagnosis of BCNT enrolled in the American College of Surgeons National Surgical Quality Improvement Program registry from 2011 to 2015. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.09.081DOI Listing
January 2019
11 Reads