11,079 results match your criteria Skull Base Benign Tumors


An Intraventricular Type of Chondroma : A Case Report.

Turk Neurosurg 2019 Mar 7. Epub 2019 Mar 7.

IUMS.

Introduction: Intracranial chondromas are unusual benign tumors. They commonly occur at the base of the skull, whereas an intraventricular type is very rare.

Case Report: We present the case of a 19-year-old female patient with a giant intraventricular chondroma detected incidentally by imaging after a car accident. Read More

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http://www.turkishneurosurgery.org.tr/summary_en_doi.php3?do
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http://dx.doi.org/10.5137/1019-5149.JTN.25478-18.2DOI Listing
March 2019
2 Reads

Reconstruction of the anterior craniocervical junction using an expandable cage after resection of a C1 chordoma in a 5-year-old child: case report.

J Neurosurg Pediatr 2019 Apr 12:1-4. Epub 2019 Apr 12.

1Section of Pediatric Neurosurgery, Riley Hospital for Children, Department of Neurological Surgery, Indiana University School of Medicine, Goodman Campbell Brain and Spine, Indianapolis, Indiana; and.

Chordomas are histologically benign tumors with local aggressive behavior. They arise from embryological remnants of the notochord at the clivus, mobile spine, and sacrum. Chordomas are rare tumors in the pediatric age group. Read More

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http://dx.doi.org/10.3171/2019.2.PEDS18752DOI Listing
April 2019
1 Read

MRI predictive score of pial vascularization of supratentorial intracranial meningioma.

Eur Radiol 2019 Apr 8. Epub 2019 Apr 8.

Department of Radiology, Centre Hospitalier et Universitaire Dupuytren, 2 Avenue Martin Luther King, 87042, Limoges, France.

Objective: Meningiomas are highly vascularized tumors which may recruit pial blood supply. Pial supply complicates tumor treatment in numerous ways. The objective of this study was to establish a reliable MRI-based diagnostic score to predict the existence of pial blood supply in supratentorial intracranial meningiomas and then correlate the score with clinical and surgical outcomes and histopathological findings. Read More

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http://dx.doi.org/10.1007/s00330-019-06197-6DOI Listing
April 2019
1 Read

Effect of perioperative aspirin use on hemorrhagic complications in elective craniotomy for brain tumors: results of a single-center, retrospective cohort study.

J Neurosurg 2019 04 5:1-10. Epub 2019 Apr 5.

Objective: In daily practice, neurosurgeons face increasing numbers of patients using aspirin (acetylsalicylic acid, ASA). While many of these patients discontinue ASA 7–10 days prior to elective intracranial surgery, there are limited data to support whether or not perioperative ASA use heightens the risk of hemorrhagic complications. In this study the authors retrospectively evaluated the safety of perioperative ASA use in patients undergoing craniotomy for brain tumors in the largest elective cranial surgery cohort reported to date. Read More

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http://dx.doi.org/10.3171/2018.12.JNS182483DOI Listing
April 2019
3 Reads

Surgical Approach to Frontal Sinus Osteoma: A Systematic Review.

Am J Rhinol Allergy 2019 Apr 5:1945892419839895. Epub 2019 Apr 5.

1 Department of Otolaryngology-Head and Neck Surgery, University of Texas Medical Branch, Galveston, Texas.

Background: Osteoma of the paranasal sinuses are benign bony masses most commonly found in the frontal sinus. In the past, due to the anatomical complexity of the frontal sinus, these often required an open approach, but with the invention of angled tools and endoscopes, many rhinologists are now attempting endoscopic or combined resections. No large systematic reviews currently exist that describe the surgical management of frontal sinus osteoma. Read More

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http://dx.doi.org/10.1177/1945892419839895DOI Listing
April 2019
4 Reads

Chordomas: Histopathological Study in View of Anatomical Location.

J Korean Med Sci 2019 Apr 8;34(13):e107. Epub 2019 Apr 8.

Department of Pathology, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, Korea.

Background: Chordomas are aggressive bone tumors that have a predilection for the axial skeleton including the skull base and spinal/sacral bones. However, the histopathological and clinical differences between skull base chordoma (SBC) and sacral/spinal chordoma (SC) are unclear as previous studies have been focused on patient prognosis and treatment outcome. This study aimed to evaluate the clinicopathologic features and prognosis of chordoma according to its location. Read More

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http://dx.doi.org/10.3346/jkms.2019.34.e107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449597PMC
April 2019
2 Reads

Endoscopic anatomical study of the trans-lateral molar approach to the infratemporal fossa.

Eur Arch Otorhinolaryngol 2019 Apr 3. Epub 2019 Apr 3.

Department of Otolaryngology-Head and Neck Surgery, The Third Affiliated Hospital, Sun Yat-sen University, No. 600 Tianhe Road, Tianhe District, Guangzhou, 510630, Guangdong, China.

Background: The infratemporal fossa (ITF) is located deep in the skull base. Recently, the endoscopic transoral approach has enabled maxillofacial surgeons to access the ITF using a less invasive approach compared to the traditional transfacial and endonasal endoscopic approaches.

Objective: The present study aims to provide maxillofacial surgeons with new data concerning direct endoscopic measurement and precise anatomical topography features of the endoscopic trans-lateral molar approach to ITF by comparing the endoscopic and regional anatomy of ITF. Read More

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http://dx.doi.org/10.1007/s00405-019-05409-5DOI Listing
April 2019
5 Reads

Hearing Preservation in Vestibular Schwannoma Surgery.

J Neurol Surg B Skull Base 2019 Apr 10;80(2):149-155. Epub 2019 Jan 10.

Department of Otolaryngology - Head and Neck Surgery, Southern California Kaiser Permanente Medical Group, San Diego, California, United States.

Modern imaging techniques allow early detection of small vestibular schwannomas (VSs) with minimal or no hearing impairment. While controversy surrounds the management of these tumors, given their benign nature and unpredictable natural history, microsurgical excision is the only modality that offers the opportunity to cure the tumor and preserve hearing. Hearing preservation in VS surgery may be accomplished via the middle fossa or retrosigmoid approaches. Read More

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http://dx.doi.org/10.1055/s-0038-1677550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438818PMC
April 2019
2 Reads

Anterior skull base reconstruction after tumour resection using the posterior wall of the frontal sinus.

Eur Ann Otorhinolaryngol Head Neck Dis 2019 Mar 20. Epub 2019 Mar 20.

Service de neurochirurgie, CHU Maison Blanche, 45, rue Cognacq-Jay, 51100 Reims, France.

Introduction: The authors describe their experience of surgical closure of the anterior skull base after tumour resection, using the posterior wall of the frontal sinus.

Material And Method: The authors describe their anterior skull base closure technique performed in three patients after tumour resection. Tumour resection via a transglabellar approach resulted in an anterior skull base defect. Read More

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http://dx.doi.org/10.1016/j.anorl.2019.02.016DOI Listing
March 2019
1 Read

The epidemiology of central and extraventricular neurocytoma in the United States between 2006 and 2014.

J Neurooncol 2019 Mar 11. Epub 2019 Mar 11.

Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, Cleveland Clinic, Cleveland, OH, USA.

Introduction: Central neurocytoma (CN) and extraventricular neurocytoma (EVN) are rare intracranial tumors. There is a paucity of studies reporting the population-based incidence of these tumors. We used the Central Brain Tumor Registry of the United States (CBTRUS), which contains the largest aggregation of population-based data on the incidence of primary central nervous system tumors in the United States to describe these tumors. Read More

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http://dx.doi.org/10.1007/s11060-019-03144-9DOI Listing
March 2019
1 Read

[Extirpation of primary malignancies in the pterygopalatine and infratemporal fossa via modified maxillary swing approach].

Zhonghua Kou Qiang Yi Xue Za Zhi 2019 Mar;54(3):194-197

Department of Head and Neck Surgery, Hunan Cancer Hospital, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha 410013, China.

Five patients with primary malignancies in the pterygopalatine fossa (PPF) and infra temporal fossa (ITF) were enrolled in this retrospective study between January 2012 and January 2018. After malignancies proven by biopsy and evaluation with CT and MRI scan, all patients received modified maxillary swing (MMS) approach for extirpation of malignant tumors in the PPF and ITF under general anesthesia. En bloc resection with wide surgical margins was successfully performed in all cases. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1002-0098.2019.03.009DOI Listing
March 2019
2 Reads

Transjugular transsigmoid approach for triple dumbbell-shaped jugular foramen schwannomas.

Acta Neurochir (Wien) 2019 Apr 4;161(4):739-743. Epub 2019 Mar 4.

Department of Neurosurgery, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.

Background: Jugular foramen tumors, particularly those that are triple dumbbell-shaped with intracranial, intraforaminal, and extracranial extensions, are difficult to access surgically. However, advances in neuroimaging, neuromonitoring, and skull base surgery have enabled their safe resection with lower rates of morbidity and mortality.

Method: We share our experience with the surgical technique for the management of triple dumbbell-shaped jugular foramen schwannomas. Read More

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http://dx.doi.org/10.1007/s00701-019-03860-1DOI Listing

Desmoid tumor after resection of cerebellar hemangioblastoma.

J Neurosurg Sci 2019 Apr;63(2):224-230

Skull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Science, Tehran, Iran.

Desmoid tumors are histologically benign but locally invasive tumors that rarely can occur in the head and neck. In this article, we illustrate a rare case of desmoid tumor formation in intracranial posterior fossa after suboccipital craniotomy for hemangioblastoma. A 43-year-old woman presented with headaches, dizziness, equilibrium disorders, nausea, and vomiting due to a hemangioblastoma in posterior fossa. Read More

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http://dx.doi.org/10.23736/S0390-5616.16.03398-1DOI Listing
April 2019
3 Reads
0.780 Impact Factor

Cerebral infarction after fractionated stereotactic radiation therapy of benign anterior skull base tumors.

Clin Transl Radiat Oncol 2019 Feb 7;15:93-98. Epub 2019 Feb 7.

Department of Neurosurgery, Rigshospitalet, Copenhagen, Denmark.

Background: The purpose of this study was to examine the occurrence of cerebral infarction (ischemic stroke), in a large combined cohort of patients with anterior skull base meningiomas, pituitary adenomas and craniopharyngiomas, after fractionated stereotactic radiation therapy (FSRT).

Material And Methods: All patients, 18 years and older, with anterior skull base meningiomas, pituitary adenomas and craniopharyngiomas, treated with fractionated stereotactic radiation, in our center, from January 1999 to December 2015 were identified. In total 169 patients were included. Read More

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http://dx.doi.org/10.1016/j.ctro.2019.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378839PMC
February 2019
1 Read

Recovery period of sinonasal quality of life and its associated factors after endoscopic endonasal approach for anterior skull base tumors.

Acta Otolaryngol 2019 Feb 26:1-6. Epub 2019 Feb 26.

d Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul, Republic of Korea.

Background: Although endoscopic endonasal approach (EEA) for skull base tumors showed a good prognosis in sinonasal quality of life (QOL), what factors have influence on QOL is still in question. Aim/Objectives: To investigate the recovery of sinonasal QOL after EEA for anterior skull base tumors and find its prognostic factors.

Material And Methods: The study enrolled 250 patients undergoing EEA for anterior skull base tumors over 3 years. Read More

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http://dx.doi.org/10.1080/00016489.2019.1574982DOI Listing
February 2019
1 Read
0.990 Impact Factor

Whole-tumor histogram analysis of apparent diffusion coefficient in differentiating intracranial solitary fibrous tumor/hemangiopericytoma from angiomatous meningioma.

Eur J Radiol 2019 Mar 22;112:186-191. Epub 2019 Jan 22.

Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. Electronic address:

Purpose: To assess the role of histogram analysis of apparent diffusion coefficient (ADC) maps based on whole-tumor in differentiating intracranial solitary fibrous tumor/hemangiopericytoma (SFT/HPC) from angiomatous meningioma (AM).

Materials And Methods: Pathologically confirmed intracranial SFT/HPC (n = 15) and AM (n = 20) were retrospectively collected and their clinical and conventional MRI features were analyzed. Diffusion-weighted (DW) images (b = 0 and 1000 s/mm) were processed with the mono-exponential model. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.01.023DOI Listing
March 2019
9 Reads

Radiologic Features of Primary Intracranial Myxomas from the Skull Base: 14 Case Reports and Literature Review.

World Neurosurg 2019 Feb 7. Epub 2019 Feb 7.

Department of Neuroradiology, Tiantan Hospital, Capital Medical University, Beijing, China. Electronic address:

Background: Primary intracranial myxomas (PIMs) are extremely rare benign tumors that arise from the skull base. The aim of this study was to characterize the radiologic manifestation of PIMs in a series of 14 cases.

Methods: We reviewed the imaging and clinical data of 14 patients with pathologically proven PIMs. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.174DOI Listing
February 2019
2 Reads

Proposal for Modification of Cahan's Criteria Utilizing Molecular Genetic Analyses for Cases without Baseline Histopathology: A Unique Method Applicable to Primary Radiosurgery.

J Neurol Surg B Skull Base 2019 Feb 31;80(1):10-17. Epub 2018 May 31.

Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota, United States.

 Cahan's criteria have been utilized since 1948 to establish causality between prior radiation treatment and the development of secondary malignancy. One major criterion specifies that histological and radiographic evidence collected before and after radiation treatment must confirm separate tumor types; however, pretreatment biopsy is rarely obtained prior to radiosurgery for vestibular schwannoma and many other skull base and cranial lesions. Therefore, in these cases Cahan's criteria cannot be validly applied. Read More

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http://dx.doi.org/10.1055/s-0038-1655759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365249PMC
February 2019
2 Reads

Letter to the Editor Regarding "Combined Minimally Invasive Supraciliary and Transfacial Approach for Large Tumors with Skull Base and Sinonasal Involvement".

World Neurosurg 2019 02;122:707

Department of ENT and Head and Neck Surgery, All India Institute of Medical Sciences, Ansari Nagar East, New Delhi, India.

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http://dx.doi.org/10.1016/j.wneu.2018.09.043DOI Listing
February 2019
1 Read

A step towards international prospective trials in carbon ion radiotherapy: investigation of factors influencing dose distribution in the facilities in operation based on a case of skull base chordoma.

Radiat Oncol 2019 Feb 1;14(1):24. Epub 2019 Feb 1.

Service de Cancérologie-Radiothérapie, Hôpital A.Michallon, CHU de Grenoble, Grenoble, France.

Background: Carbon ion radiotherapy (CIRT) has been delivered to more than 20,000 patients worldwide. International trials have been recommended in order to emphasize the actual benefits. The ULICE program (Union of Light Ion Centers in Europe) addressed the need for harmonization of CIRT practices. Read More

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http://dx.doi.org/10.1186/s13014-019-1224-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359776PMC
February 2019
3 Reads

[Indication for Radiotherapy for Breast Cancer Metastasis to the Skull Base Accompanied by Cranial Nerve Palsies].

Gan To Kagaku Ryoho 2018 Dec;45(13):1806-1808

Dept. of Surgery, Southern Tohoku General Hospital.

Distant metastasis to the skull base region frequently manifests various cranial nerve symptoms and reduces patients' quality of life(QOL). We report a 62-year-old woman with skull base metastasis of breast cancer, whose condition clinically improved following palliative radiotherapy. The patient presented to our hospital with hoarseness. Read More

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December 2018
2 Reads

Comparison of multi-shot and single shot echo-planar diffusion tensor techniques for the optic pathway in patients with neurofibromatosis type 1.

Neuroradiology 2019 Apr 25;61(4):431-441. Epub 2019 Jan 25.

Department of Pediatrics, Section of Hematology/Oncology, Indiana University School of Medicine, Indiana, IN, USA.

Purpose: Diffusion tensor imaging (DTI) may be helpful in assessing optic pathway integrity as a marker for treatment in neurofibromatosis type 1 (NF1) patients with optic gliomas (OG). However, susceptibility artifacts are common in typical single-shot echo planar imaging (ssDTI). A readout-segmented multi-shot EPI technique (rsDTI) was utilized to minimize susceptibility distortions of the skull base and improve quantitative metrics. Read More

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http://dx.doi.org/10.1007/s00234-019-02164-6DOI Listing

Malignant peripheral nerve sheath tumor of the nasal cavity and nasopharynx in a child: A case report.

Medicine (Baltimore) 2019 Jan;98(4):e14223

Department of Radiology, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.

Rationale: Malignant peripheral nerve sheath tumors (MPNSTs) are rare neoplasms with only a few reported cases affecting the nasal cavity, paranasal sinuses, and anterior skull base.

Patient Concerns: A 12-year-old girl with a mass in her nose was admitted to the Department of Otorhinolaryngology of Shenzhen Children's Hospital. She had a 4-month history of progressive, unilateral right nasal obstruction, unilateral mucopurulent rhinorrhea, foul nasal odor, snoring, hyposmia, occasional epistaxis, and no headache, no facial numbness, without eye swelling and vision loss. Read More

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http://dx.doi.org/10.1097/MD.0000000000014223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358413PMC
January 2019
9 Reads
5.723 Impact Factor

Grading of MRI-detected skull-base invasion in nasopharyngeal carcinoma with skull-base invasion after intensity-modulated radiotherapy.

Radiat Oncol 2019 Jan 17;14(1):10. Epub 2019 Jan 17.

Department of Radiation Oncology, Zhejiang Cancer Hospital, Hangzhou, 310022, China.

Background: The aim of this study is to evaluate the prognostic value of grading MRI-detected skull-base invasion in nasopharyngeal carcinoma (NPC) with skull-base invasion after intensity-modulated radiotherapy (IMRT).

Methods: This study is a retrospective chart review of 469 non-metastatic NPC patients with skull-base invasion. Patients were classified as extensive skull-base invasion (ESBI) group and limited skull-base invasion (LSBI) group. Read More

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http://dx.doi.org/10.1186/s13014-019-1214-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335845PMC
January 2019
1 Read

Long-term impact of pediatric endoscopic endonasal skull base surgery on midface growth.

J Neurosurg Pediatr 2019 01 11:1-8. Epub 2019 Jan 11.

Departments of1Plastic Surgery.

OBJECTIVE Cranial base development plays a large role in anterior and vertical maxillary growth through 7 years of age, and the effect of early endonasal cranial base surgery on midface growth is unknown. The authors present their experience with pediatric endoscopic endonasal surgery (EES) and long-term midface growth. METHODS This is a retrospective review of cases where EES was performed from 2000 to 2016. Read More

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http://dx.doi.org/10.3171/2018.8.PEDS18183DOI Listing
January 2019
2 Reads

Rapidly Growing and Asymptomatic Skull Base Lesion.

J Craniofac Surg 2019 Jan 10. Epub 2019 Jan 10.

Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas.

Trochlear schwannomas typically present with diplopia and are extremely rare benign intracranial neoplasms that require the combined expertise of neurotologists and neurosurgeons for surgical excision. A combined petrosal approach offers a surgical route for removal of growing and/or symptomatic tumors. A study of a trochlear nerve schwannoma that demonstrated rapid growth but was otherwise asymptomatic was presented in this study. Read More

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http://dx.doi.org/10.1097/SCS.0000000000005153DOI Listing
January 2019
2 Reads

Skull base angiomatous leiomyoma: a case report and review of literature.

Br J Neurosurg 2019 Jan 12:1-3. Epub 2019 Jan 12.

b Department of Neurosurgery , Royal Hallamshire Hospital , Sheffield , UK.

Leiomyomas, benign neoplasms of mesenchymal origin, are common in gastrointestinal and genitourinary tracts. They are comprised of well-differentiated smooth muscle cells with few mitotic figures. Leiomyomas should not exhibit metastatic potential, though metastasis has been reported. Read More

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http://dx.doi.org/10.1080/02688697.2018.1555636DOI Listing
January 2019
5 Reads

Sino-orbital desmoid tumor in a pediatric patient - Case report with review of literature.

Orbit 2018 Dec 27:1-9. Epub 2018 Dec 27.

e Department of Pediatric Oncology , National University Health System , Singapore , Singapore.

We report a case of a 2-year-old female who presented with bilateral progressive proptosis, visual loss, nasal obstruction, and breathing difficulty. Magnetic resonance imaging revealed a large sino-orbital mass that was extending to the orbital apex and skull base. An initial diagnosis of rhabdomyosarcoma was made elsewhere on the basis of the presence of round and spindle cell tumor. Read More

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http://dx.doi.org/10.1080/01676830.2018.1556306DOI Listing
December 2018
3 Reads

Radiation-Induced Moyamoya Syndrome After Proton Therapy in Child with Clival Chordoma: Natural History and Surgical Treatment.

World Neurosurg 2019 Mar 22;123:306-309. Epub 2018 Dec 22.

Department of Neurosurgery, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini, Genoa, Italy.

Background: Proton therapy has proven to be effective and safe in the treatment of radioresistant skull base tumors such as chordomas. Thanks to the peculiar physical properties of the proton beam, radiation energy is delivered in a narrow space called the Bragg peak and the surrounding normal tissues receive a minimal amount of the radiation dose. This is important to lower the risk of radiation-induced damage, especially in children. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183287
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http://dx.doi.org/10.1016/j.wneu.2018.12.048DOI Listing
March 2019
26 Reads

Dorsally Displaced Facial Nerve in Retrosigmoid Transmeatal Approach for Vestibular Schwannoma: 3-Dimensional Operative Video.

World Neurosurg 2019 Mar 21;123:300. Epub 2018 Dec 21.

Department of Neurosurgery, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan.

Dorsal displacement of the facial nerve is relatively rare in patients with vestibular schwannoma. Its prediction remains difficult in patients with large tumors, even with the recent advances in preoperative radiologic assessments. Anatomic and functional preservation of the facial nerves combined with maximal tumor removal is particularly challenging in this rare anatomic variant, and surgery may lead to postoperative facial dysfunction, inadequate tumor removal, and/or a high retreatment rate. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.11.261DOI Listing
March 2019
3 Reads

Characteristics and management of sinonasal paragangliomas: a systematic review.

Int Forum Allergy Rhinol 2019 Apr 20;9(4):413-426. Epub 2018 Dec 20.

Department of Otolaryngology-Head and Neck Surgery, Rutgers New Jersey Medical School, Newark, NJ.

Background: Paragangliomas of the nasal cavity and paranasal sinuses, although exceedingly rare, can exhibit frequent and aggressive recurrences. Our objective was to evaluate tumor characteristics, clinical course, management, and associated complications of sinonasal paragangliomas METHODS: A systematic review of the literature was performed utilizing the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines, searching for sinonasal paraganglioma. Studies meeting inclusion criteria were assessed for level of evidence. Read More

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http://doi.wiley.com/10.1002/alr.22261
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http://dx.doi.org/10.1002/alr.22261DOI Listing
April 2019
17 Reads
2.371 Impact Factor

Immature Teratoma of Nasal Septum: A Case Report.

Iran J Otorhinolaryngol 2018 Nov;30(101):355-359

Department of Otorhinolaryngology, Topiwala National Medical College and BYL Nair Hospital, Mumbai, Maharashtra, India.

Introduction: Teratomas are neoplastic tumors derived from totipotent germ cells containing a wide assortment of tissues originating from all three germ cell layers. Teratomas can be mature or immature depending on the presence of immature tissues; typically neuroepithelial tissue. Immature teratomas can be oncologically benign or malignant, and can be divided into three grades with increasingly aggressive biological behavior. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291815PMC
November 2018
1 Read

[The surgical management of upper parapharyngeal regions].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1804-1809

Department of Otorhinolaryngology, the First Affiliated Hospital, Bengbu Medical College, Bengbu, 233004, China.

To find proper the surgical approval and evaluate clinical efficacy to treat the tumor of upper parapharyngeal space involving the base of skull and intracranial skull. The data of 9 cases from June 2013 and June 2018 were analyzed retrospectively including schwannoma in 6 cases, pleomorphic adenoma in 2 cases and hemangioma in 1 case. All cases received preoperative high resolution CT and MRI, some cases also did the DSA examination. Read More

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http://www.cnki.net/kcms/doi/10.13201/j.issn.1001-1781.2018.
Publisher Site
http://dx.doi.org/10.13201/j.issn.1001-1781.2018.23.009DOI Listing
December 2018
19 Reads

[Application of image-guided system in endoscopic sinus and skull base surgery].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(24):1856-1859

Department of Otorhinolaryngology Head and Neck Surgery, Huadong Hospital, Fudan University, Shanghai, 200040,China.

To evaluate the applicative value of image-guided system in endoscopic sinus and skull base surgeries. A total of 103 endoscopic surgical procedures were performed.All these procedures were conducted with the utilization of image-guided system, among which there were 92 cases of sinonasal-skull base surgery(including nasal sinuses resection of benign and malignant tumors involving skull base lesions, the cumulative orbital lesion resection of nasal sinus lesions, etc. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2018.24.003DOI Listing
December 2018
2 Reads

Surgical management and prognostic factors for primary intracranial myxoma: a single-institute experience with a systematic review.

J Neurosurg 2018 Nov 1:1-11. Epub 2018 Nov 1.

1Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University; and.

OBJECTIVEPrimary intracranial myxomas (PICMs) are extremely rare neoplasms, and their management and prognostic factors remain ambiguous. The authors aimed to elaborate the radiological features, evaluate the risk factors for progression-free survival (PFS), and propose a treatment protocol based on pooled data from cases treated at their institute and those found in the literature.METHODSClinical data from all cases of PICMs treated at the authors' institute and those cases reported in the English-language literature between 1987 and December 2017 were reviewed. Read More

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http://dx.doi.org/10.3171/2018.6.JNS181132DOI Listing
November 2018
2 Reads
3.737 Impact Factor

KTP-laser-assisted endoscopic management of glomus tympanicum tumors: A case series.

Ear Nose Throat J 2018 Dec;97(12):399-402

Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, 801 Welch Rd., Stanford, CA 94035, USA.

Endoscopic technology is widely used in rhinology and anterior skull base surgery, but it has been less quickly incorporated into otologic practice. The design of the instrumentation forces surgeons to work one-handed and limits depth perception. Nevertheless, endoscopy also offers wide fields of view and access to spaces that are typically difficult to visualize. Read More

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http://dx.doi.org/10.1177/014556131809701209DOI Listing
December 2018
17 Reads

Proton therapy for treatment of intracranial benign tumors in adults: A systematic review.

Cancer Treat Rev 2019 Jan 1;72:56-64. Epub 2018 Dec 1.

Radiation Oncology Department, Centre François Baclesse, Caen, France; Archade, Advanced Resource Center for Hadrontherapy in Europe, Caen, France; Normandy University, Université de Caen Basse Normandie, Caen, France; Laboratoire de Physique Corpusculaire, Caen, France.

Introduction: The depth-dose distribution of a proton beam, materialized by the Bragg peak makes it an attractive radiation modality as it reduces exposure of healthy tissues to radiations, compared with photon therapy Prominent indications, based on a long-standing experience are: intraocular melanomas, low-grade skull-base and spinal canal malignancies. However, many others potential indications are under investigations such as the benign morbid conditions that are compatible with an extended life-expectancy: low grade meningiomas, paragangliomas, pituitary adenomas, neurinomas craniopharyngioma or recurrent pleomorphic adenomas.

Materials: Given the radiation-induced risk of secondary cancer and the potential neurocognitive and functional alteration with photonic radiotherapy, we systematically analyzed the existing clinical literature about the use of proton therapy as an irradiation modality for cervical or intracranial benign tumors. Read More

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http://dx.doi.org/10.1016/j.ctrv.2018.11.004DOI Listing
January 2019
3 Reads

Preservation of Venous Drainage in Middle Fossa During Combined Transpetrosal Approach for Petroclival Meningioma.

World Neurosurg 2019 Mar 6;123:67. Epub 2018 Dec 6.

Department of Neurosurgery, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan.

The combined transpetrosal approach enables wide exposure around the petroclival region by lifting of the middle fossa dura and cutting of the tentorium. However, interruption of the venous drainage on the middle skull base during the transpetrosal approach has been reported to lead to temporal lobe damage.Video 1 demonstrates a microsurgical technique for the preservation of various venous drainage in the middle fossa including the sphenobasal and sphenopetrosal veins during the combined transpetrosal approach for treatment of a petroclival meningioma. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.11.215DOI Listing
March 2019
3 Reads

Epithelioid Osteoblastoma of the Temporal Bone: A Case Report.

World Neurosurg 2019 Mar 3;123:378-382. Epub 2018 Dec 3.

Department of Pathology, University of California, Los Angeles, California, USA. Electronic address:

Background: Epithelioid osteoblastoma of the cranium is extremely rare and can mimic other etiologies on radiographic imaging, pathology, and symptomatology.

Case Description: An 18-year-old male patient had a 3-week history of a palpable left temporal mass. Magnetic resonance imaging revealed a large, extra-axial, hypervascular mass in the left temporal bone, with bony erosion and intracranial extension. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183276
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http://dx.doi.org/10.1016/j.wneu.2018.11.209DOI Listing
March 2019
31 Reads

Ultrasonic Scalpel-Assisted Endoscopic Endonasal Surgery of Infratemporal Fossa: Our First Impressions.

World Neurosurg 2019 Mar 3;123:23-28. Epub 2018 Dec 3.

Division of Otorhinolaryngology, Department of Biotechnology and Life Sciences, Head and Neck Surgery & Forensic Dissection Research Center, University of Insubria, Varese, Italy.

Background: The endoscopic endonasal transpterygoid approach is emerging as a valid option for treating selected tumors in the infratemporal fossa. Compared with traditional open approaches, the endoscopic endonasal approach presents more difficulty in controlling bleeding and less choice in surgical instruments for endoscopic tumor dissection, which is often performed with bipolar forceps or steel dissectors.

Case Description: We describe the use of an ultrasonic scalpel device for performing endoscopic endonasal resection of 2 rare infratemporal fossa tumors (mature teratoma and hemangiopericytoma), which has not been reported in the literature so far. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183276
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http://dx.doi.org/10.1016/j.wneu.2018.11.202DOI Listing
March 2019
15 Reads

The rhinologist's role in the management of rathke's cleft cysts.

Curr Opin Otolaryngol Head Neck Surg 2019 Feb;27(1):67-71

Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadephia, Pennsylvania, USA.

Purpose Of Review: To review the recent literature regarding the growing role of rhinologists and otolaryngologists with neurosurgeons in the joint multidisciplinary team approach for managing patients with Rathke's cleft cysts (RCC).

Recent Findings: The transnasal endoscopic approach to the skull base has become relatively mainstream for surgical treatment of RCCs. Suprasellar lesions, especially those that are purely suprasellar, are associated with higher recurrence rates, though an extended approach may improve dissection and access and therefore aid in lesion removal. Read More

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http://dx.doi.org/10.1097/MOO.0000000000000512DOI Listing
February 2019
3 Reads

Meningiomas Display a Specific Immunoexpression Pattern in a Rostrocaudal Gradient: An Analysis of 366 Patients.

World Neurosurg 2019 Mar 29;123:e520-e535. Epub 2018 Nov 29.

Department of Neurosurgery, School of Medicine, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Turkey. Electronic address:

Background: Meningiomas are heterogeneous, with differences in anatomical, histopathological, and clinical characteristics. Such spatial variability in meningioma biology is thought to result from differences in the expression of critical developmental regulators. We hypothesized that the variability in meningioma biology would follow gradients such as in embryology and tested a cohort of 366 meningiomas for histopathological and immunohistochemical gradients. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.11.201DOI Listing
March 2019
3 Reads
2.417 Impact Factor

A rare case of intracranial malignant triton tumor arising in the middle cranial fossa: a case report and review of the literature.

Folia Neuropathol 2018 ;56(3):229-234

We describe a rare case of intracranial malignant triton tumor (MTT) arising in the middle cranial fossa in a 74-year-old female patient who had previously been exposed to radiation in the Chernobyl disaster. The patient underwent a surgical subtotal removal of the mass and radiation therapy, but the progression-free survival was only 2.5 months and death occurred four months after the onset of symptoms. Read More

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http://dx.doi.org/10.5114/fn.2018.78704DOI Listing
March 2019
3 Reads

Surgical management and long-term outcomes of intracranial giant cell tumors: a single-institution experience with a systematic review.

J Neurosurg 2018 Oct 1:1-11. Epub 2018 Oct 1.

1Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing; and.

OBJECTIVEIntracranial giant cell tumors (GCTs) are extremely rare neoplasms with dismal survival and recurrence rates. The authors aimed to confirm independent adverse factors for progression-free survival (PFS) and to propose an optimal treatment algorithm.METHODSThe authors reviewed the clinical data of 43 cases of intracranial GCTs in their series. Read More

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http://dx.doi.org/10.3171/2018.4.JNS1849DOI Listing
October 2018
6 Reads
3.737 Impact Factor

Epidemiology of meningiomas. A nationwide study of surgically treated tumours on French medico-administrative data.

Cancer Epidemiol 2019 Feb 24;58:63-70. Epub 2018 Nov 24.

Department of Medical Information, Georges Pompidou European Hospital, 75015, Paris, France.

Background: To describe the epidemiology of surgically treated meningiomas and compare the results with previously published studies.

Methods: We processed the French medico-administrative national hospital discharge summary database, Programme de Médicalisation des Systèmes d'Information (PMSI) using an algorithm combining the type of surgical procedure and codes from the International Classification of Diseases to retrieve appropriate cases of meningiomas operated between 2008 and 2016.

Results: This nationwide study found 25,737 cases of operated meningiomas. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18777821183022
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http://dx.doi.org/10.1016/j.canep.2018.11.004DOI Listing
February 2019
12 Reads

Intraoral Endoscopic Ligation of Maxillary Artery in the Infratemporal Fossa.

J Craniofac Surg 2019 Jan;30(1):137-140

Department of Otolaryngology - Head and Neck Surgery, Endoscopic Sinus Surgery and Skull Base Surgery, Autonomous University of Veracruz, Xalapa, Mexico.

Ligation of the sphenopalatine and posterior nasal arteries is indicated for posterior epistaxis as initial treatment or when conservative measures fail. In some patients, a transnasal approach or its alternative transantral approach are not possible due to tumor filling the nasal corridor, pterygopalatine fossa, or maxillary sinus. Aim of this study was to evaluate feasibility of endoscopically assisted transoral approach for the ligation of the maxillary artery (MA). Read More

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http://dx.doi.org/10.1097/SCS.0000000000004981DOI Listing
January 2019
25 Reads

Treatment outcomes of proton or carbon ion therapy for skull base chordoma: a retrospective study.

Radiat Oncol 2018 Nov 26;13(1):232. Epub 2018 Nov 26.

Department of Radiology, Hyogo Ion Beam Medical Center, Tatsuno, Hyogo, Japan.

Background: The usefulness of particle therapy for skull base chordoma has not been established. The aim of this retrospective study was to analyse the treatment outcomes of proton therapy (PT) and carbon ion therapy (CIT) in patients with skull base chordoma at a single institution.

Methods: All patients who underwent PT or CIT with curative intent between 2003 and 2014 at Hyogo Ion Beam Medical Center were included in this study. Read More

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https://ro-journal.biomedcentral.com/articles/10.1186/s13014
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http://dx.doi.org/10.1186/s13014-018-1173-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260885PMC
November 2018
10 Reads

Primary Lymphoma of the Skull Base in the Chinese: Clinical, Radiological, Pathological, and Therapeutic Experience in a Series of 8 Patients.

World Neurosurg 2019 Mar 23;123:e171-e179. Epub 2018 Nov 23.

Department of Neurosurgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Electronic address:

Background: Primary lymphoma of the skull base (PLSB) is an extremely rare neoplasm and not much is known regarding the clinical features of, treatment strategies for, and prognoses of these lesions. We investigated the manifestations and clinical outcomes of Chinese patients with PLSB.

Methods: We retrospectively reviewed the data from 8 consecutive patients with PLSB who had been treated at our center from October 2008 to December 2016 and analyzed their clinical features, treatment strategies, and prognoses. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183265
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http://dx.doi.org/10.1016/j.wneu.2018.11.109DOI Listing
March 2019
22 Reads

Massive aneurysmal bone cyst of the skull base treated with denosumab.

Head Neck 2018 Dec 26;40(12):E107-E113. Epub 2018 Nov 26.

Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Background: Aneurysmal bone cysts are rare, benign expansile tumors most commonly involving long bones and vertebrae in patients younger than age 20. Skull base involvement is rare. Aneurysmal bone cysts shares radiological and histological features with other bone tumors, posing a diagnostic challenge. Read More

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http://doi.wiley.com/10.1002/hed.25438
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http://dx.doi.org/10.1002/hed.25438DOI Listing
December 2018
19 Reads

Glioblastoma with bilateral extraocular muscle infiltration preceded by evidence of vascular tropism.

J Clin Neurosci 2019 Mar 22;61:277-278. Epub 2018 Nov 22.

Division of Medical Oncology, Mayo Clinic, United States.

We present a case of bilateral synchronous orbital muscle infiltration of extra-neural glioblastoma metastases with evidence of focal treatment response. The orbital infiltration was preceded by evidence of leptomeningeal disease, and followed by further symptomatic perineural spread of tumor along the second and third division of the trigeminal nerve and into the masticator space. Read More

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http://dx.doi.org/10.1016/j.jocn.2018.11.017DOI Listing
March 2019
3 Reads