13,507 results match your criteria Skull Base Anatomy

[Giant petrosal meningioma invading the fourth ventricle: total removal of a recurrent tumor after eighteen years. Neurosurgical nuances. Case report and literature review].

Zh Vopr Neirokhir Im N N Burdenko 2022 ;86(3):77-82

Blokhin National Cancer Research Center, Moscow, Russia.

The authors present a patient and neurosurgical nuances of total resection of recurrent meningioma of posterior surface of petrous bone 65´35´30 mm. The tumor captured two critical zones of posterior cranial fossa with unusual frontal growth and spread from the surface of petrous bone to the fourth ventricle. The neoplasm filled the ventricle without lesion of ependyma. Read More

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The petrosal artery and its variations: a comprehensive review and anatomical study with application to skull base surgery and neurointerventional procedures.

Folia Morphol (Warsz) 2022 Jun 13. Epub 2022 Jun 13.

Department of Structural and Cellular Biology, Tulane University School of Medicine, New Orleans, LA, United States.

Background: The petrosal artery supplies several structures at the skull base and is often the focus of various neurointerventional procedures. Therefore, knowledge of its anatomy and variations is important to surgeons and interventionalists.

Materials And Methods: Twenty latex injected cadaveric heads (40 sides) underwent microsurgical dissection of the petrosal artery. Read More

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A giant foramen of Vesalius: case report.

Anat Cell Biol 2022 Jun 13. Epub 2022 Jun 13.

Department of Neurosurgery, Tulane Center for Clinical Neurosciences, Tulane University School of Medicine, New Orleans, LA, USA.

Anatomical variations identified at the skull base can result in challenges to the clinician. For example, the anatomy of the foramen ovale and its neighboring structures is critical knowledge for the surgeon who performs transcutaneous approaches to the foramen ovale for treating patients with trigeminal neuralgia. One nearby structure that can compound invasive procedures and potentially result in complications is the foramen of Vesalius. Read More

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Salvage Endoscopic Skull Base Surgery: Another Treatment Option After Immunotherapy for Recurrent Nasopharyngeal Carcinoma.

Front Immunol 2022 24;13:899932. Epub 2022 May 24.

Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, China.

Background: Advanced recurrent nasopharyngeal carcinoma (NPC) is a relatively common nasopharyngeal skull base disease for which there is no uniform treatment modality. Not all patients are satisfied with the efficacy of immunotherapy with or without chemotherapy.

Methods: This study included patients who underwent salvage endoscopic skull base nasopharyngectomy after immunotherapy between February 2017 and June 2021. Read More

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Infra-Temporal and Pterygo-Palatine Fossae Tumors: A Frontier in Endoscopic Endonasal Surgery-Description of the Surgical Anatomy of the Approach and Report of Illustrative Cases.

Int J Environ Res Public Health 2022 May 25;19(11). Epub 2022 May 25.

Programma Neurochirurgia Ipofisi-Pituitary Unit, IRCCS Istituto delle Scienze Neurologiche di Bologna, 40139 Bologna, Italy.

Infratemporal and pterygopalatine fossae (ITF and PPF) represent two complex paramedian skull base areas, which can be defined as jewelry boxes, containing a large number of neurovascular and osteomuscular structures of primary importance. They are in close communication with many craniofacial areas, such as nasal/paranasal sinuses, orbit, middle cranial fossa, and oral cavities. Therefore, they can be involved by tumoral, infective or inflammatory lesions spreading from these spaces. Read More

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Oropharyngeal neuroglial choristoma with extension into the parapharyngeal space.

Radiologia (Engl Ed) 2022 May-Jun;64(3):270-273

Radiólogo, Hospital Pequeno Príncipe, Curitiba, Paraná, Brazil.

Oropharyngeal neuroglial choristomas are exceptionally rare head and neck tumours that contain mature neuroglial tissue. We report a case of neuroglial choristoma centred in the oropharynx and extending into the parapharyngeal space that, to the best of our knowledge, is the only case whose appearance simulated brain cortical gyri with an apparent differentiation between white and grey matter. We illustrate and detail the magnetic imaging findings of oropharyngeal choristoma that might help to establish a correct preoperative diagnosis. Read More

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Giant dwarf crocodiles from the Miocene of Kenya and crocodylid faunal dynamics in the late Cenozoic of East Africa.

Anat Rec (Hoboken) 2022 Jun 8. Epub 2022 Jun 8.

Department of Earth Sciences, National Museums of Kenya, Nairobi, Kenya.

We describe two new osteolaemine crocodylids from the Early and early Middle Miocene of Kenya: Kinyang mabokoensis tax. nov. (Maboko, 15 Ma) and Kinyang tchernovi tax. Read More

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[Malignant solitary fibrous tumors: a clinicopathological and molecular genetic analysis].

Zhonghua Bing Li Xue Za Zhi 2022 Jun;51(6):518-523

Department of Pathology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.

To explore the clinicopathological features, immunophenotype and molecular genetic characteristics of malignant solitary fibrous tumor (MSFT). Seven cases of MSFT were collected from the First Affiliated Hospital of Zhengzhou University from July 2018 to December 2020. Immunohistochemistry, RNA-based NGS and DNA-based NGS were performed. Read More

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Implications of the olfactory fossa anatomy in intracranial complications of inferomedial orbital decompression.

Orbit 2022 Jun 7:1-4. Epub 2022 Jun 7.

Department of Ophthalmology, Otorhinolaryngology, and Head and Neck Surgery, School of Medicine of Ribeirão Preto, University of Sao Paulo, Sao Paulo, Brazil.

Two patients with thyroid eye disease underwent inferomedial orbital decompression complicated by a cerebrospinal fluid (CSF) leak. One of the cases developed a postoperative pneumocephalus resolved with conservative measures. In the second case, the CSF leak was managed intraoperatively. Read More

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[Surgical Strategy of Benign Skull Base Tumors Based on Membrane Structure].

No Shinkei Geka 2022 May;50(3):681-694

Department of Neurosurgery, The Jikei University School of Medicine.

Meningiomas, schwannomas, and pituitary adenomas are typically benign tumors of intracranial origin, but all of these tumors have a border with the surrounding tissue. The basic structure is a clear "boundary" between the tumor and its surroundings, with a thin membrane layer to create that separation. This layer of membrane is the boundary between the tumor and its surroundings and provides a space for the tumor to grow its cells, and can be viewed as the so-called "tumor capsule. Read More

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[How to Use a High-Speed Drill and an Ultrasonic Aspirator During Skull Base Surgery].

No Shinkei Geka 2022 May;50(3):650-654

Department of Neurosurgery, Osaka Metropolitan University, Graduate School of Medicine.

During surgery for skull base lesions, maximum efforts should be made to improve the removal rate of the lesion while avoiding complications, and it is necessary to expand the surgical field by selecting appropriate surgical instruments and equipment. In both microsurgery and endoscopic surgery, high-speed drills and ultrasonic aspirators contribute significantly to the safe and reliable removal of skull base lesions, and the surgeons need to be familiar with these characteristics. The specific vital points are as follows: (1) Preparation of the appropriate environment for using a high-speed drill or an ultrasonic aspirator with the understanding of the microsurgical anatomy, (2) Bone excision using a high-speed drill with the selection of an appropriate drill attachment or drill bar tip according to the site of use, (3) Internal decompression of lesions using an ultrasonic aspirator with appropriate settings, (4) Additional expansion of the surgical field by using an ultrasonic aspirator in the osteotomy mode, and so on. Read More

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[The Anterior Transpetrosal Approach].

No Shinkei Geka 2022 May;50(3):614-624

Department of Neurosurgery, Keio University School of Medicine.

The Anterior transpetrosal approach is a skull base surgical procedure that can provide a wide operative view of the petroclival and the prepontine region. This approach requires one to accurately understand the anatomy of the anterior part of the temporal bone and the histological structure of the dura mater. In addition, it is necessary to learn operative techniques for venous preservation, accurate hemostasis at each step, and prevention of cerebrospinal fluid leakage. Read More

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[Common Sense in Head and Neck Surgery for Malignant Skull Base Disease:Lack of Common Sense in Neurosurgery].

Takahiro Asakage

No Shinkei Geka 2022 May;50(3):578-585

Department of Head and Neck Surgery, Tokyo Medical and Dental University Hospital.

Skull base surgery for malignant skull base disease is one of the most difficult surgeries. The success of the surgery depends on the harmonization of the excellent skills of the three departments: neurosurgery, otorhinolaryngology/head and neck surgery, and plastic surgery. In addition, it is necessary to perform complete resection, that is, resection in which the malignant tumor is removed along with some surrounding healthy tissue. Read More

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[Latest Findings on Meningioma:WHO grades 1/2/3].

Soichi Oya

No Shinkei Geka 2022 May;50(3):564-571

Department of Neurosurgery, Saitama Medical Center.

While most meningiomas are histologically benign tumors, higher grade meningiomas classified as WHO grades 2 and 3 are not always amenable to the standard treatment. To accurately assess the biological characteristics and prognosis of the tumor, the WHO classification of meningiomas has been continuously revised based on the latest findings. This article describes the recent modifications of the WHO classification of meningiomas. Read More

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[Skull Base Vessel Anatomy].

No Shinkei Geka 2022 May;50(3):544-553

Department of Neurosurgery, Tokai University School of Medicine.

Knowledge of the arterial and venous anatomy of the skull base is essential to interventional neuroradiologists in assuring a safe procedure. The anatomy of this area is complex and difficult to master in a short period of time. However, knowing some basic rules and starting from basic structures facilitates learning. Read More

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[Anatomy for Endoscopic Endonasal Skull Base Surgery].

No Shinkei Geka 2022 May;50(3):535-543

Department of Otolaryngology-Head and Neck Surgery, Nagoya City University, Graduate School of Medical Sciences.

Endoscopic endonasal skull base surgery has become popular due to its minimally invasive nature to the patient and the development of various medical devices. The reason why it is considered less invasive is that it is possible to reach the anterior skull base lesion using the corridor of the nasal cavity and paranasal sinuses. The roles of the nasal sinuses include acting as breathing pathways, warming, humidifying, and filtering of inhaled air, olfaction, and being a resonant cavity, all of which are important for a comfortable life, and the loss of these functions reduces the quality of life. Read More

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[Microneurosurgical Anatomy of the Posterior fossa and Craniocervical Junction].

No Shinkei Geka 2022 May;50(3):525-534

Department of Neurosurgery, Fukuoka University.

The posterior fossa is a site where blood vessels and nerves are very dense, so surgery can be very difficult. Therefore, serious sequelae may occur due to complications. Surgeons should be familiar with the complex anatomy of the posterior fossa. Read More

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[Microsurgical Anatomy of the Petrous Part of the Temporal Bone].

No Shinkei Geka 2022 May;50(3):516-524

Department of Neurosurgery, Osaka Medical and Pharmaceutical University School of Medicine.

For a surgeon to become skilled at skull base surgery, they should have mastered the three-dimensional anatomy of the petrous part of the temporal bone. The anatomy encountered during surgery is demonstrated from the superior, posterior, and lateral aspects of the petrous bone. The landmarks of the superior aspect of the petrous bone are the third division of the trigeminal nerve, the petrous ridge, the arcuate eminence, the greater superficial petrosal nerve, and the internal carotid artery. Read More

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[History of Skull Base Surgery].

Akio Morita

No Shinkei Geka 2022 May;50(3):496-507

Department of Neurological Surgery, Nippon Medical School.

Skull base surgery is a surgical field that involves the cooperation of multiple surgical and medical specialties, including neurosurgery, head-neck surgery, plastic-reconstructive surgery, radiation oncology, as well as multiple medical supporting teams. This field has been developed with the collaborative efforts of these medical specialties, and its history can be divided into five phases: Beginning of surgery(Prior to 1940); Early skull base surgery driven by the ENT-HN surgery group(1940-70); Conventional skull base surgery development based on anatomical, physiological knowledge and microsurgical equipment and technique(1970-90); Reflection and consolidation of the surgical dimension(1995-2005); and Evolution of endoscopic and new skull base surgical techniques(2005-). Several topics and advancements have improved this surgical field, such as access to the cavernous sinus, petrosal-temporal bone, and foramen magnum; concepts of minimally invasive surgical techniques; advanced endoscopic instruments; knowledge of biological assessments; and development of surgical robotics. Read More

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Current opinions on diagnosis and treatment of adenoid cystic carcinoma.

Oral Oncol 2022 Jul 2;130:105945. Epub 2022 Jun 2.

Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China; Otolaryngology Major Disease Research Key Laboratory of Hunan Province, Changsha, Hunan 410008, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China; Anatomy Laboratory of Division of Nose and Cranial Base, Clinical Anatomy Center of Xiangya Hospital, Central South University, Changsha, Hunan 410008, China. Electronic address:

Adenoid cystic carcinoma (ACC) is a rare malignant tumor derived mainly from the salivary glands, representing approximately 1% of all headandneck carcinomasand 10% of all salivary gland neoplasms. ACC displays a paradoxical behavioral combination of an indolent growth pattern but an aggressive progression, with local recurrence and distant metastasis. The propensity of ACC of the head and neck (ACCHN) for perineural invasion and its anatomical location, especially if it extends to the nasal cavity and paranasal sinuses, facilitates tumor involvement in the surrounding structures, such as the orbit, pterygopalatine fossa, Meckel'scave, and cavernous sinus, which can lead to skull base involvement and intracranial extension. Read More

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Anatomy and Diseases of the Greater Wings of the Sphenoid Bone.

Radiographics 2022 Jun 3:210094. Epub 2022 Jun 3.

From the Department of Radiology, Instituto Nacional de Câncer (INCA), Praça Cruz Vermelha 23, Rio de Janeiro, RJ, Brazil 20230-130 (R.C., J.A., C.A.d.A., R.P.S., M.F.U., A.P.K.C., G.S.M., G.R.S.d.N., F.M., M.D.); and Department of Radiology, Medical College of Wisconsin, Milwaukee, Wis (M.A.).

The greater wings of the sphenoid bone (GWS) comprise the components of the sphenoid bone that make up most of the posterior orbital wall and form the anterior and medial parts of the floor of the middle cranial fossa. Many important skull base foramina, which transmit vital neurovascular structures, are present in these paired wings on either side of the central body of the sphenoid bone. A wide variety of diseases can affect the GWS, ranging from benign osseus lesions to malignant primary and secondary bone abnormalities. Read More

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Surgical Experience of Transcranial Approaches to Large-to-Giant Pituitary Adenomas in Knosp Grade 4.

Front Endocrinol (Lausanne) 2022 12;13:857314. Epub 2022 May 12.

Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

Pituitary adenomas in Knosp grade 4 are difficult to resect completely and are generally involved in poor prognosis, because of the close relationship between the tumor and internal carotid. In this study, the authors retrospectively reviewed the outcome of different transcranial approaches in the management of large-to-giant pituitary adenomas in Knosp grade 4. A total of 42 patients with large-to-giant pituitary adenomas in Knosp grade 4, who underwent craniotomy in the Pituitary Disease Subdivision, Department of Neurosurgery, Beijing Tiantan Hospital, between March 2012 and March 2015 were included in this study. Read More

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Three-hundred and sixty degrees of surgical approaches to the maxillary sinus.

World J Otorhinolaryngol Head Neck Surg 2022 Mar 22;8(1):42-53. Epub 2022 Mar 22.

Division of Rhinology and Skull Base Surgery, Department of Otolaryngology-Head & Neck Surgery Mayo Clinic Rochester Minnesota USA.

Objectives: To demonstrate three-hundred and sixty degrees of maxillary sinus (MS) surgical approaches using cadaveric dissections, highlighting the step-by-step anatomy of each procedure.

Methods: Two latex-injected cadaveric specimens were utilized to perform surgical dissections to demonstrate different approaches to the MS. The procedures were documented with macroscopic images and endoscopic pictures. Read More

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Endoscopic endonasal approach to the craniovertebral junction.

World J Otorhinolaryngol Head Neck Surg 2022 Mar 14;8(1):16-24. Epub 2022 Mar 14.

Department of Neurological Surgery University of Texas Southwestern Medical Center Dallas Texas USA.

The surgical approach to lesions of the ventral craniovertebral junction (CVJ) has evolved significantly in the last several years with the advent of endoscopic skull base surgery. Differing pathologies of the CVJ can result in irreducible compression of the cervicomedullary region. The endoscopic endonasal approach lends itself well to this region due to the ventral location, and while there is a steep learning curve, is a safe and effective way to perform decompression of the cervicomedullary region. Read More

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How I do it? Resection of residual petrous apex chordoma with combined endoscopic endonasal and contralateral transmaxillary approaches.

Acta Neurochir (Wien) 2022 Jul 26;164(7):1967-1972. Epub 2022 May 26.

Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, 200040, China.

Background: The petrous apex is one of the most challenging areas of the skull base to access.

Method: We present a case of residual petrous apex chordoma posterolateral to the paraclival segment of the internal carotid artery (ICA) resected with combined endoscopic endonasal and contralateral transmaxillary (CTM) approaches, without lateralization of the ICA.

Conclusion: This case demonstrates the value of the CTM corridor in resecting petrous apex lesions that are posterolateral to the paraclival segment of the ICA. Read More

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Localisation of the petrous internal carotid artery relative to the vidian canal on computed tomography: a case-control study evaluating the impact of petroclival chondrosarcoma.

Acta Neurochir (Wien) 2022 Jul 25;164(7):1939-1948. Epub 2022 May 25.

School of Biomedical Engineering and Imaging Sciences, St Thomas' Hospital, King's College, London, SE1 7EH, UK.

Background: The vidian canal (VC) is normally a reliable anatomical landmark for locating the petrous internal carotid artery (pICA). This study determined the influence of petroclival chondrosarcoma on the relationship between the VC and pICA.

Methods: Nine patients (3 males, 6 females; median age 49) with petroclival chondrosarcoma, and depiction of the pICA on contrast-enhanced CT, were retrospectively studied. Read More

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Ossification of Pterygospinous and Pterygoalar Ligaments and Their Clinical Significance: An Anatomic Study.

Rajani Singh

J Craniofac Surg 2022 May 25. Epub 2022 May 25.

Department of Anatomy, UP University of Medical Sciences, Etawah, India.

Abstract: Pterygospinous and pterygoalar ligaments, present in close proximity of foramen ovale at the base of skull, ossify creating pterygospinous and pterygoalar foramina, which causes problems in accessing retro and parapharyngeal spaces, trigeminal ganglion for treating trigeminal neuralgia by thermocoagulation and blocking it. Besides, these anatomical entities may compress nearby neurovascular structures causing discomfort to patients. considering immense clinical significance associated with ossification of pter-ygospinous and pterygoalar ligaments, the study has been carried out. Read More

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The anti-angiogenic effect of atorvastatin loaded exosomes on glioblastoma tumor cells: An in vitro 3D culture model.

Microvasc Res 2022 May 21;143:104385. Epub 2022 May 21.

Nervous System Stem Cells Research Center, Semnan University of Medical Sciences, Semnan, Iran; Department of Tissue Engineering and Applied Cell Sciences, School of Medicine, Semnan University of Medical Sciences, Semnan, Iran. Electronic address:

Exosomes are endogenous nanoparticles with a lipid bilayer membrane whose natural function as carriers of biological materials has attracted much attention. The ability of exosomes to cross biological barriers, especially the blood-brain barrier, has highlighted them as tools of drug delivery to brain tumors. In a previous study, we isolated and characterized exosomes derived from human endometrial mesenchymal stem cells (hEnMSCs exosomes). Read More

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A Case of Adult Clival Osteomyelitis.

J Investig Med High Impact Case Rep 2022 Jan-Dec;10:23247096221101858

Robert Wood Johnson Barnabas Health and Trinitas Regional Medical Center, Elizabeth, NJ, USA.

Clival osteomyelitis is a potentially life-threatening skull base infection. It is rare and generally challenging to diagnose and treat. Clival osteomyelitis is typically seen in the pediatric population and is very rare in the adult population. Read More

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Patient Benefit and Quality of Life after Robot-Assisted Head and Neck Surgery.

Timon Hussain

Laryngorhinootologie 2022 May 23;101(S 01):S160-S185. Epub 2022 May 23.

Klinik für Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie, Universitätsklinikum Essen, Universität Duisburg-Essen.

Robotic systems for head and neck surgery are at different stages of technical development and clinical application. Currently, robotic systems are predominantly used for transoral surgery of the pharynx and larynx. Robotic surgery of the neck, the thyroid, and the middle and inner ear is much less common; however, some oncological and functional outcomes have been reported. Read More

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