646 results match your criteria Skull Base Acoustic Neuroma Vestibular Schwannoma


The Patient-Centered Approach: A Review of the Literature and Its Application for Acoustic Neuromas.

J Neurol Surg B Skull Base 2020 Jun 6;81(3):280-286. Epub 2019 Jun 6.

Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut, United States.

Patient-centered care is defined as "care that is consistent with and respects the values, needs, and wishes of patients" and is best achieved when clinicians involve patients and their support system in health care discussions and decisions. While this approach has been well established and supported in more general medical specialties, such as primary care, that may encompass a more holistic approach, it has rarely been described in surgical disciplines. Acoustic neuromas (ANs) can be unique among other skull base and intracranial pathologies, in that the management of these tumors can vary from patient to patient depending on various factors. Read More

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http://dx.doi.org/10.1055/s-0039-1692396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253312PMC

Prediction of vestibular schwannoma recurrence using artificial neural network.

Laryngoscope Investig Otolaryngol 2020 Apr 17;5(2):278-285. Epub 2020 Feb 17.

Division of Neurotology and Skull Base Surgery, Department of Otolaryngology-Head and Neck Surgery University of California Irvine California.

Objectives: To compare two statistical models, namely logistic regression and artificial neural network (ANN), in prediction of vestibular schwannoma (VS) recurrence.

Methods: Seven hundred eighty-nine patients with VS diagnosis completed an online survey. Potential predictors for recurrence were derived from univariate analysis by reaching the cut off value of . Read More

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http://dx.doi.org/10.1002/lio2.362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178452PMC

Inpatient and outpatient case prioritization for patients with neuro-oncologic disease amid the COVID-19 pandemic: general guidance for neuro-oncology practitioners from the AANS/CNS Tumor Section and Society for Neuro-Oncology.

J Neurooncol 2020 May 9;147(3):525-529. Epub 2020 Apr 9.

Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.

The Coronavirus pandemic has created unprecedented strain on medical resources at health care institutions around the world. At many institutions, this has resulted in efforts to prioritize cases with an attempt to balance the acuity of medical needs with available resources. Here, we provide a framework for institutions and governments to help adjudicate treatment allocations to patients with neuro-oncologic disease. Read More

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http://dx.doi.org/10.1007/s11060-020-03488-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145274PMC

Predictive Value of Preoperative and Intraoperative Neurophysiology in Evaluating Long-term Facial Function Outcome in Acoustic Neuroma Surgery.

Otol Neurotol 2020 Apr;41(4):530-536

Department of Otorhinolaryngology and Skull Base Microsurgery-Neurosciences, Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy.

Objective: To determine the role of neurophysiological preoperative and intraoperative parameters in providing prognostic information regarding facial nerve (FN) function at 1 year after translabyrinthine acoustic neuroma (AN) resection surgery.

Study Design: Prospective observational study in a tertiary referral center. Patients treated via translabyrinthine surgical approach for sporadic AN microresection between December 2015 and 2018. Read More

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http://dx.doi.org/10.1097/MAO.0000000000002553DOI Listing

MRI monitoring of small and medium-sized vestibular schwannomas: predictors of growth.

Acta Otolaryngol 2020 May 12;140(5):361-365. Epub 2020 Feb 12.

Department of Otolaryngology and Otoneurosurgery, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Claude Bernard University Lyon 1, Lyon, France.

Vestibular schwannomas are among the most common intracranial tumours. Their growth is difficult to predict. To study the evolution of small and medium-sized vestibular schwannomas (VSs) and identify factors predictive of growth. Read More

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http://dx.doi.org/10.1080/00016489.2020.1717608DOI Listing

Comments on 'Screening for vestibular schwannoma in the context of an ageing population'.

J Laryngol Otol 2020 03 10;134(3):275-276. Epub 2020 Feb 10.

Department of Skull Base Surgery, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, UK.

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http://dx.doi.org/10.1017/S0022215120000043DOI Listing

Clinical Predictors Leading to Change of Initial Conservative Treatment of 836 Vestibular Schwannomas.

J Neurol Surg B Skull Base 2020 Feb 4;81(1):15-21. Epub 2019 Feb 4.

Department of ENT, Leiden University Medical Center, Leiden, The Netherlands.

 This study was aimed to determine the role of clinical presentation and tumor characteristics in vestibular schwannoma (VS) at diagnosis, initially treated with conservative management.  The study was designed as a retrospective chart review.  The study was prepared at national tertiary referral center for VS patients. Read More

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http://dx.doi.org/10.1055/s-0039-1678708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996999PMC
February 2020

The Influence of Vestibular Schwannoma Tumor Volume and Growth on Hearing Loss.

Otolaryngol Head Neck Surg 2020 Apr 28;162(4):530-537. Epub 2020 Jan 28.

Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota, USA.

Objective: To ascertain the relationship among vestibular schwannoma (VS) tumor volume, growth, and hearing loss.

Study Design: Retrospective cohort study.

Setting: Single tertiary center. Read More

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http://dx.doi.org/10.1177/0194599819900396DOI Listing
April 2020
1.721 Impact Factor

Patient Demographics Influencing Vestibular Schwannoma Size and Initial Management Plans.

World Neurosurg 2020 Apr 10;136:e440-e446. Epub 2020 Jan 10.

Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, USA. Electronic address:

Objective: To explore patient demographics as to predicting vestibular schwannoma (VS) size and treatment plan within a single institution.

Methods: Using a large tertiary referral skull base center database, all patients with sporadic VS who presented to the center between 2009 and 2018 were reviewed.

Results: A total of 816 patients with VS over 18 years of age were included. Read More

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http://dx.doi.org/10.1016/j.wneu.2020.01.019DOI Listing

Comparison between VII-to-VII and XII-to-VII coaptation techniques for early facial nerve reanimation after surgical intra-cranial injuries: a systematic review and pooled analysis of the functional outcomes.

Neurosurg Rev 2020 Jan 7. Epub 2020 Jan 7.

Department of Neurosurgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

The surgical injury of the intracranial portion of the facial nerve (FN) is a severe complication of many skull base procedures, and it represents a relevant issue in terms of patients' discomfort, social interactions, risk for depression, and social costs. The aim of this study was to investigate the surgical and functional outcomes of the most common facial nerve rehabilitation techniques. The present study is a systematic review of the pertinent literature, according to the PRISMA guidelines. Read More

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http://dx.doi.org/10.1007/s10143-019-01231-zDOI Listing
January 2020

The Jugular Process: A Key Anatomical Landmark for Approaches to the Jugular Foramen.

World Neurosurg 2020 Mar 27;135:e686-e694. Epub 2019 Dec 27.

Department of Neurotomy, Beijing Neurosurgical Institute, Beijing, China; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. Electronic address:

Objective: To describe the morphology and anatomical relationship of the jugular process (JP) and to elucidate its utility as a surgical landmark in the lateraland posterior lateral approaches to the jugular foramen.

Materials And Methods: Eight dry adult skulls and 10 silicon-injected cadaver heads were used for this study. The distances to selected structures and the thickness of the JP at 3 selected sites were measured. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.12.103DOI Listing
March 2020
2.417 Impact Factor

Transcanal Transpromontorial Approach to Lateral Skull Base: Maximal Area of Exposure and Surgical Extensions.

World Neurosurg 2020 Mar 26;135:e181-e186. Epub 2019 Nov 26.

Department of Otolaryngology Head and Neck Surgery, Inselspital University Hospital and University of Bern, Bern, Switzerland; Hearing Research Laboratory, ARTORG Center for Biomedical Engineering, University of Bern, Bern, Switzerland.

Objective: To determine the possible surgical extensions and maximal area of exposure (AOE) achievable through the transcanal transpromontorial approach (TTA) to the internal auditory canal (IAC) and cerebellopontine angle. We hypothesize a possible extension of indication for this minimally invasive approach to the lateral skull base.

Methods: In this experimental anatomic study, the expanded TTA was first carried out in 4 temporal bones to define the anatomic boundaries of the maximal exposure, from 2 perspectives, the middle ear and the porus of the IAC. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.11.102DOI Listing

Cochlear Implantation in Sporadic Vestibular Schwannoma: A Systematic Literature Review.

J Neurol Surg B Skull Base 2019 Dec 8;80(6):632-639. Epub 2019 Jan 8.

Department of Otolaryngology-Head and Neck Surgery, Loyola University Medical Center, Maywood, Illinois, United States.

 This study was aimed to perform a systematic literature review by examining outcomes in patients with sporadic vestibular schwannoma (VS) undergoing ipsilateral cochlear implant (CI).  PubMed-NCBI (National Center for Biotechnology Information) and Scopus databases were searched through October 2017.  Studies reporting auditory outcomes for each patient when a CI was placed with an ipsilateral sporadic VS were included. Read More

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http://dx.doi.org/10.1055/s-0038-1676768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864424PMC
December 2019

Durability of Hearing Preservation Following Microsurgical Resection of Vestibular Schwannoma.

Otol Neurotol 2019 12;40(10):1363-1372

Department of Otolaryngology-Head and Neck Surgery.

Objective: To ascertain long-term hearing outcomes in patients with serviceable hearing following microsurgical resection of sporadic vestibular schwannoma (VS).

Study Design: Retrospective cohort.

Setting: Tertiary academic referral center. Read More

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http://dx.doi.org/10.1097/MAO.0000000000002378DOI Listing
December 2019
1.598 Impact Factor

The endoscopic anatomy of the cochlear hook region and fustis: surgical implications.

Acta Otorhinolaryngol Ital 2019 Oct;39(5):353-357

Department of Otolaryngology Head and Neck Surgery, University Hospital of Modena, Italy.

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http://dx.doi.org/10.14639/0392-100X-2388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843579PMC
October 2019

Subclinical vestibular deficit in six-canal video head impulse testing (vHIT) in patients with vestibular schwannomas.

Clin Otolaryngol 2020 Jan 27;45(1):139-142. Epub 2019 Nov 27.

Department of Otolaryngology, Queen Elizabeth University Hospital, Glasgow, UK.

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http://dx.doi.org/10.1111/coa.13470DOI Listing
January 2020

Management of sporadic vestibular schwannoma with contralateral nonserviceable hearing.

Laryngoscope 2020 Jun 23;130(6):E407-E415. Epub 2019 Oct 23.

Otorhinolaryngology Department, Unit of Otology, Auditory Implants and Skull Base Surgery, Greater paris university hospitals, Pitié-Salpêtrière University Group Hospital, Paris, France.

Objectives/hypothesis: To outline a possible decision-making process for sporadic vestibular schwannoma (VS) with contralateral nonserviceable hearing at diagnosis.

Study Design: Retrospective case series.

Methods: Diagnosed VS was studied in a tertiary referral center from 1995 to 2013. Read More

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http://dx.doi.org/10.1002/lary.28369DOI Listing
June 2020
7 Reads

The Role for Imaging in the Investigation of Isolated Objective Vestibular Weakness.

Otolaryngol Head Neck Surg 2019 12 1;161(6):1027-1030. Epub 2019 Oct 1.

Department of Otolaryngology-Head and Neck Surgery, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.

Objective: Unilateral vestibular weakness has considerable potential etiologies. One source is a vestibular schwannoma. This article evaluates, in the absence of other symptoms and signs, if unilateral vestibular weakness is an analogue to asymmetric sensorineural hearing loss and serves as an indication for lateral skull base imaging. Read More

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http://dx.doi.org/10.1177/0194599819877691DOI Listing
December 2019
1 Read

Contemporary Opinions on Intraoperative Facial Nerve Monitoring.

OTO Open 2018 Jul-Sep;2(3):2473974X18791803. Epub 2018 Aug 7.

New York Otology, New York, New York, USA.

Objective: To examine the current trend in intraoperative facial nerve monitoring (IOFNM) training, performance, and reimbursement by subspecialists.

Study Design: Cross-sectional survey of the American Neurotology Society, American Otological Society, American Society of Pediatric Otolaryngology, and program directors of otolaryngology-head and neck surgery programs accredited by the Accreditation Council on Graduate Medical Education.

Setting: American Academy of Otolaryngology-Head and Neck Surgery Intraoperative Nerve Monitoring Task Force. Read More

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http://dx.doi.org/10.1177/2473974X18791803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737880PMC
August 2018
3 Reads

Long-Term Effects of Bevacizumab on Vestibular Schwannoma Volume in Neurofibromatosis Type 2 Patients.

J Neurol Surg B Skull Base 2019 Oct 17;80(5):540-546. Epub 2018 Dec 17.

Department of Otolaryngology - Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, United States.

 Bevacizumab offers a medical treatment that may slow the growth of vestibular schwannomas (VS) and possibly preserve hearing in patients with neurofibromatosis type 2 (NF2). This study aims to investigate the effect of long-term bevacizumab treatment on VS progression.  Demographic, clinical, audiometric, and radiographic data were collected from the medical records of NF2 patients treated with bevacizumab at a tertiary medical center. Read More

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http://dx.doi.org/10.1055/s-0038-1676628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748845PMC
October 2019
3 Reads

Hearing rehabilitation outcomes in cochlear implant recipients with vestibular schwannoma in observation or radiotherapy groups: A systematic review.

Cochlear Implants Int 2020 Jan 8;21(1):9-17. Epub 2019 Sep 8.

Cambridge Skull Base Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.

Vestibular schwannomas (VS) are rare benign tumours of the vestibular nerve that cause hearing loss. Management strategies include watchful waiting, radiotherapy or surgical resection. Historically, the presence of retrocochlear disease has been considered to be a contra-indication to cochlear implantation (CI). Read More

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http://dx.doi.org/10.1080/14670100.2019.1662161DOI Listing
January 2020
10 Reads

Hearing preservation in vestibular schwannoma surgery via retrosigmoid transmeatal approach.

Acta Neurochir (Wien) 2019 11 7;161(11):2265-2269. Epub 2019 Aug 7.

Department of Neurosurgery, Tokyo Medical University, No. 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.

Background: Advances in various diagnostic and/or treatment modalities, including radiological imaging, neuromonitoring, and microsurgical techniques, have resulted in treatments of vestibular schwannomas being aimed at preserving facial and hearing functions while achieving optimal tumor control.

Method: We describe our surgical technique for hearing preservation in vestibular schwannoma surgery.

Conclusion: The retrosigmoid transmeatal approach under continuous neuromonitoring (auditory brainstem response, cochlear nerve action potentials, and continuous facial nerve monitoring) enables gross-total resection of vestibular schwannomas, while preserving hearing and facial functions. Read More

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http://dx.doi.org/10.1007/s00701-019-04034-9DOI Listing
November 2019
1 Read

A Cross-Sectional Survey of the North American Skull Base Society Part 3: The State of Lateral Skull Base Surgery Training in North America.

J Neurol Surg B Skull Base 2019 Aug 5;80(4):399-415. Epub 2018 Nov 5.

Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic School of Medicine, Rochester, Minnesota, United States.

 Optimal management of vestibular schwannoma (VS) demands involvement of an experienced multidisciplinary team. As the number of training programs in neurotology and skull base neurosurgery continues to rise, ensuring that trainees are capable of evidence-based decision-making and treatment, whether microsurgical or radiosurgical, is of paramount importance. The purpose of this study is to characterize the landscape of neurotologic and neurosurgical fellowship training programs in North America, with special reference to VS management. Read More

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http://dx.doi.org/10.1055/s-0038-1675557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635112PMC
August 2019
2 Reads

When Should We Stop Scanning Older Patients with Vestibular Schwannomas?

J Neurol Surg B Skull Base 2019 Aug 27;80(4):333-337. Epub 2018 Dec 27.

Department of Skull Base Surgery, Addenbrooke's Hospital, Cambridge University Hospitals, Cambridge, United Kingdom.

 Observation is a well-accepted management for small- to medium-sized vestibular schwannomas (VSs). Although there are good data on the natural history of this disease within adults, no studies have looked specifically at those aged over 70 years. Thus, there is a need for a surveillance protocol to determine if and when we can stop imaging safely patients aged 70 years and over with a new diagnosis of VSs when managed with observation. Read More

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http://dx.doi.org/10.1055/s-0038-1676820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635115PMC
August 2019
8 Reads

Benefits of pre-labyrinthectomy intratympanic gentamicin: contralateral vestibular responses.

J Laryngol Otol 2019 Aug 16;133(8):668-673. Epub 2019 Jul 16.

Department of Otolaryngology, Queen Elizabeth University Hospital, Glasgow, Scotland, UK.

Objective: To determine the impact of pre-operative intratympanic gentamicin injection on the recovery of patients undergoing translabyrinthine resection of vestibular schwannomas.

Methods: This prospective, case-control pilot study included eight patients undergoing surgical labyrinthectomy, divided into two groups: four patients who received pre-operative intratympanic gentamicin and four patients who did not. The post-operative six-canal video head impulse test responses and length of in-patient stay were assessed. Read More

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http://dx.doi.org/10.1017/S0022215119001002DOI Listing
August 2019
3 Reads

Middle Fossa Approach for Facial Nerve Schwannoma Aiming for Functional Improvement: 2-Dimensional Operative Video.

Oper Neurosurg (Hagerstown) 2020 May;18(5):E167-E168

Department of Neurosurgery, Tokyo Medical University, Tokyo, Japan.

The treatment paradigm of skull base surgery has been changed from radical tumor resection to maximal tumor removal while giving priority to functional preservation. Facial nerve schwannoma is one of the representative disorders of this type of paradigm shift.1 This video demonstrates facial nerve schwannoma surgery through the middle fossa approach, aiming for improvement of facial function. Read More

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http://dx.doi.org/10.1093/ons/opz178DOI Listing
May 2020
6 Reads

Audiological Evaluation of Vestibular Schwannoma Patients with Normal Hearing.

Audiol Neurootol 2019 2;24(3):117-126. Epub 2019 Jul 2.

Department of Neurotology and Skull Base Surgery, Gruppo Otologico, Piacenza/Rome, Italy.

Objective: To evaluate the audiological aspects of vestibular schwannoma (VS) patients with normal hearing.

Study Design: Retrospective study.

Setting: Quaternary referral center for skull base pathologies. Read More

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http://dx.doi.org/10.1159/000500660DOI Listing
April 2020
3 Reads

How to radiologically identify a spontaneous regression of sporadic vestibular schwannoma?

PLoS One 2019 4;14(6):e0217752. Epub 2019 Jun 4.

AP-HP, Department of Neurosurgery, Hôpital Pitié-Salpétrière, Paris, France.

Background: The natural history of sporadic vestibular schwannoma is unpredictable, with tumors growing, non-growing and even showing spontaneous regression in some rare cases.

Objective: This retrospective study aims to describe the radiologic signs characterizing and identifying the shrinking vestibular schwannoma.

Methods: Involution was considered to have occurred if tumor size had decreased by 2 mm or more on its largest diameter. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0217752PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548368PMC
February 2020
24 Reads

Postoperative Hearing Preservation in Patients Undergoing Retrosigmoid Craniotomy for Resection of Vestibular Schwannomas: A Systematic Review of 2034 Patients.

Neurosurgery 2020 03;86(3):332-342

Department of Neurosurgery, University of California, Los Angeles, Los Angeles, California.

Background: Vestibular schwannomas (VS) are benign tumors derived from Schwann cells ensheathing the vestibulocochlear nerve. The retrosigmoid (RS) surgical approach is useful to resect tumors of multiple sizes while affording the possibility of preserving postoperative hearing.

Objective: To conduct a systematic review of published literature investigating hearing preservation rates in patients who underwent the RS approach for VS treatment. Read More

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http://dx.doi.org/10.1093/neuros/nyz147DOI Listing
March 2020
12 Reads

Translabyrinthine Approach for Resection of Vestibular Schwannoma.

J Neurol Surg B Skull Base 2019 Jun 1;80(Suppl 3):S286. Epub 2019 Mar 1.

Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota, United States.

 This video describes the surgical indications, relevant anatomy, and surgical steps of routine translabyrinthine surgery for gross total resection of sporadic vestibular schwannoma.  The procedure is presented through a surgical instructional video.  The surgery took place at tertiary skull base referral center. Read More

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http://dx.doi.org/10.1055/s-0039-1677856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534659PMC
June 2019
10 Reads

Retrosigmoid Approach for Resection of Large Cystic Vestibular Schwannoma.

J Neurol Surg B Skull Base 2019 Jun 26;80(Suppl 3):S285. Epub 2019 Feb 26.

Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota, United States.

 This video was aimed to describe the surgical indications, relevant anatomy, and surgical steps of retrosigmoid approach for resection of a large cystic vestibular schwannoma (VS).  The operative steps are described in a surgical instructional video.  The surgery took place at a tertiary skull base referral center. Read More

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http://dx.doi.org/10.1055/s-0039-1677850DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534657PMC
June 2019
24 Reads

Retrosigmoid Approach for Resection of Medium-Sized Vestibular Schwannoma.

J Neurol Surg B Skull Base 2019 Jun 4;80(Suppl 3):S284. Epub 2019 Mar 4.

Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota, United States.

 This video was aimed to describe the relevant anatomy and key surgical steps of retrosigmoid approach for gross total resection of a medium-sized vestibular schwannoma (VS).  The procedure is described in a surgical instructional video.  The surgery took place at a tertiary skull base referral center. Read More

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http://dx.doi.org/10.1055/s-0039-1677848DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534658PMC
June 2019
7 Reads

Hearing Preservation Surgery via Retrosigmoid Approach with Retrolabyrinthine Meatotomy in Small Vestibular Schwannoma.

J Neurol Surg B Skull Base 2019 Jun 28;80(Suppl 3):S281-S283. Epub 2019 Feb 28.

Section of Otorhinolaryngology, Department of Neurosciences, University of Padua, Padua, Italy.

 Vestibular schwannomas (VS) extending into the internal auditory canal (IAC) are currently considered as an unfavorable condition for hearing preservation surgery (HPS) via retrosigmoid (RS) approach due to the poor direct visualization of the facial and cochlear nerves course through the IAC and the fundus during microsurgery.  The operative steps are described in a surgical instructional video.  The surgery took place at a tertiary-care center. Read More

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http://dx.doi.org/10.1055/s-0039-1677847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534653PMC
June 2019
6 Reads

Endoscope-Assisted Minimally Invasive Microsurgical Removal of a Medium-Sized Acoustic Neuroma (T3a) through a Retrosigmoid Mini-Craniotomy with Preservation of Hearing.

J Neurol Surg B Skull Base 2019 Jun 18;80(Suppl 3):S276-S278. Epub 2019 Feb 18.

Department of Neurosurgery, Klinikum Stuttgart, Stuttgart, Germany.

A 45-year-old male patient with reduced hearing in the right ear was diagnosed with a medium-sized (T3a) acoustic neuroma. The operation was performed through an individually tailored retrosigmoid mini-craniotomy. Endoscope-assisted microsurgical technique was applied to early detect the location of the facial and cochlear nerves as well as to look around the hidden corners during the surgery. Read More

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http://dx.doi.org/10.1055/s-0038-1677488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534660PMC
June 2019
7 Reads

Retrosigmoid Transmeatal Approach for Resection of Acoustic Neuroma: Operative Video and Technical Nuances of Subperineural Dissection for Facial Nerve Preservation.

J Neurol Surg B Skull Base 2019 Jun 30;80(Suppl 3):S269-S270. Epub 2019 Apr 30.

Otolaryngology/Head-and-Neck Surgery, Center for Cerebrovascular and Skull Base Surgery, Rutgers University, New Jersey Medical School, Neurological Institute of New Jersey, RWJ Barnabas Health, Livingston and Newark, New Jersey, United States.

The retrosigmoid (suboccipital) approach is the workhorse for most acoustic neuromas in the cerebellopontine angle. In this operative video atlas manuscript, the authors demonstrate the nuances of the subperineural dissection technique for microsurgical resection of an acoustic neuroma via the retrosigmoid transmeatal approach. The plane is developed by separating the perineurium of the vestibular nerve away from the tumor capsule. Read More

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http://dx.doi.org/10.1055/s-0039-1688488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534509PMC
June 2019
14 Reads

Translabyrinthine Approach for Resection of Large Cystic Acoustic Neuroma: Operative Video and Technical Nuances of Subperineural Dissection for Facial Nerve Preservation.

J Neurol Surg B Skull Base 2019 Jun 24;80(Suppl 3):S267-S268. Epub 2019 Apr 24.

Otolaryngology/Head-and-Neck Surgery, Center for Cerebrovascular and Skull Base Surgery, Rutgers University, New Jersey Medical School, Neurological Institute of New Jersey, RWJ Barnabas Health, Livingston and Newark, New Jersey, United States.

The translabyrinthine approach is advantageous for the resection of large acoustic neuromas compressing the brainstem when hearing loss is nonserviceable. This approach provides wide access through the presigmoid corridor without prolonged cerebellar retraction. Early identification of the facial nerve at the fundus is also achieved. Read More

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http://dx.doi.org/10.1055/s-0039-1685534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534508PMC
June 2019
8 Reads

Main Symptom that Led to Medical Evaluation and Diagnosis of Vestibular Schwannoma and Patient-Reported Tumor Size: Cross-sectional Study in 1,304 Patients.

J Neurol Surg B Skull Base 2019 Jun 9;80(3):316-322. Epub 2018 Oct 9.

Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota, United States.

 Although vestibular schwannomas (VS) are known to cause cranial nerve deficits, cerebellar symptoms, and hydrocephalus, the role of these symptoms as the key driver of presentation from the patient's perspective has not been described. Our objective was to survey a large, retrospective VS cohort to document the patient-reported principal initial symptom, and self-reported tumor size, and to study trends in VS patient presentation.  Patients diagnosed with VS at our tertiary referral center and belonging to the Acoustic Neuroma Association (ANA) answered a questionnaire between 2015 and 2017. Read More

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http://dx.doi.org/10.1055/s-0038-1675175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534738PMC
June 2019
9 Reads

Is There a Difference in Hospital Stay between Patients undergoing Translabyrinthine or Retrosigmoid Surgery for Vestibular Schwannoma Stratified by Tumor Size?

J Neurol Surg B Skull Base 2019 Jun 25;80(3):310-315. Epub 2018 Sep 25.

Skull Base Unit, National Hospital for Neurology & Neurosurgery, Queen Square, London, United Kingdom.

 To date, no European study has compared approach-specific outcome data in vestibular schwannoma (VS) surgery stratified by tumor size. We analyzed hospital length of stay (LOS), intensive therapy/high-dependency unit (ITU/HDU) LOS, and complications in patients undergoing VS surgery via the translabyrinthine (TL) versus retrosigmoid (RS) approaches, stratifying for tumor size.  Prospective database undergoing retrospective review. Read More

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http://dx.doi.org/10.1055/s-0038-1668541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534737PMC
June 2019
9 Reads

Delayed Facial Nerve Paralysis after Vestibular Schwannoma Resection.

J Neurol Surg B Skull Base 2019 Jun 6;80(3):283-286. Epub 2018 Sep 6.

Department of Otolaryngology, Vanderbilt University Medical Center, Nashville, Tennessee, United States.

 To describe the incidence and clinical course of patients who develop delayed facial nerve paralysis (DFNP) after surgical resection of vestibular schwannoma.  Tertiary skull base center.  Retrospective chart review. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1669941
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http://dx.doi.org/10.1055/s-0038-1669941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534772PMC
June 2019
19 Reads

Identification of Predictive Proteins and Biological Pathways for the Tumorigenicity of Vestibular Schwannoma by Proteomic Profiling.

Proteomics Clin Appl 2019 09 10;13(5):e1800175. Epub 2019 Jul 10.

ENT Institute and Otorhinolaryngology Department , Affiliated Eye and ENT Hospital, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, 200031, China.

Purpose: Vestibular schwannomas (VSs) are benign tumors that account for 8-10% of all intracranial tumors. So far, the tumorigenesis of VS has not been fully elucidated. This study is designed to identify differently expressed proteins involved in VS tumorigenesis. Read More

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http://dx.doi.org/10.1002/prca.201800175DOI Listing
September 2019
13 Reads

Prognostic Factors of Long-Term Hearing Preservation in Small and Medium-Sized Vestibular Schwannomas After Microsurgery.

Otol Neurotol 2019 08;40(7):957-964

Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Ninth People's Hospital.

Objective: The authors evaluated the long-term hearing outcomes of patients with vestibular schwannoma (VS) to explore appropriate surgical treatment.

Study Design: Retrospective study.

Setting: Tertiary referral center. Read More

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http://dx.doi.org/10.1097/MAO.0000000000002284DOI Listing
August 2019
6 Reads

[18F]fluorothymidine and [18F]fluorodeoxyglucose PET Imaging Demonstrates Uptake and Differentiates Growth in Neurofibromatosis 2 Related Vestibular Schwannoma.

Otol Neurotol 2019 07;40(6):826-835

Division of Informatics, Imaging and Data Sciences, MAHSC, University of Manchester.

Objective: To investigate whether [F]fluorothymidine (FLT) and/or [F]fluorodeoxyglucose (FDG) positron emission tomography (PET) can differentiate growth in neurofibromatosis 2 (NF2) related vestibular schwannomas (VS) and to evaluate the importance of PET scanner spatial resolution on measured tumor uptake.

Methods: Six NF2 patients with 11 VS (4 rapidly growing, 7 indolent), were scanned with FLT and FDG using a high-resolution research tomograph (HRRT, Siemens) and a Siemens Biograph TrueV PET-CT, with and without resolution modeling image reconstruction. Mean, maximum, and peak standardised uptake values (SUV) for each tumor were derived and the intertumor correlation between FDG and FLT uptake was compared. Read More

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http://dx.doi.org/10.1097/MAO.0000000000002272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594723PMC
July 2019
9 Reads
1.598 Impact Factor

Is endoscopic inspection necessary to detect residual disease in acoustic neuroma surgery?

Eur Arch Otorhinolaryngol 2019 Aug 26;276(8):2155-2163. Epub 2019 Apr 26.

Otolaryngology-Head and Neck Surgery Department, University Hospital of Verona, piazzale Aristide Stefani, 1, 37126, Verona, Italy.

Main Goals: To analyze how and when the endoscope is used in vestibular schwannoma surgery and identify the benefits of using endoscopy in this type of surgery.

Background: It is currently unclear if there is any benefit from using an endoscope in vestibular schwannoma surgery so this retrospective analysis set out to study this.

Methods: All the patients who underwent vestibular schwannoma surgery at our clinic were included for all the vestibular schwannoma approaches taken. Read More

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http://link.springer.com/10.1007/s00405-019-05442-4
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http://dx.doi.org/10.1007/s00405-019-05442-4DOI Listing
August 2019
36 Reads

Ki-67 index as a predictor of vestibular schwannoma regrowth or recurrence.

J Laryngol Otol 2019 Mar;133(3):205-207

Puget Sound ENT,Proliance Surgeons,Edmonds,Washington,USA.

Background: Ki-67 is a monoclonal antibody that provides a means of evaluating the growth fraction of normal and neoplastic human cell populations. A Ki-67 index of less than 3 per cent is expected for a typical schwannoma. Vestibular schwannomas with an index of greater than 3 per cent are presumed to be actively proliferating and pose a theoretically higher risk for regrowth or recurrence. Read More

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http://dx.doi.org/10.1017/S0022215119000549DOI Listing
March 2019
9 Reads

Hand-Held Thulium Laser Fiber and Ultrasonic Aspirator for Opening the Internal Auditory Canal During Acoustic Neuroma Microneurosurgery: Operative Technique.

World Neurosurg 2019 Jun 27;126:497. Epub 2019 Mar 27.

Unit of Neurosurgery, San Filippo Neri Hospital, Rome, Italy.

Video 1 describes the technique of microsurgery removal of acoustic neuromas (ANs) using new technologies. The Flexible 2μ-Thulium hand-held laser fiber (Revolix jr, LISA laser products, 7 OHG, Berlin, Germany) and Sonopet Ultrasound Aspirator (Stryker, Kalamazoo, Michigan, USA) can be used for a safe and facilitated opening of the internal auditory canal (IAC). We illustrate the operative technique used on a surgical series of 111 cases operated on during the past 8 years, from July 2010 to July 2018. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.03.204DOI Listing
June 2019
4 Reads

Pattern of cochlear obliteration after vestibular Schwannoma resection according to surgical approach.

Laryngoscope 2020 Feb 27;130(2):474-481. Epub 2019 Mar 27.

Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota, U.S.A.

Objectives/hypothesis: To investigate the prevalence and course of cochlear obliteration according to microsurgical approach to inform clinical decision making regarding optimal timing of cochlear implantation.

Study Design: Retrospective radiologic review and chart review.

Methods: Patients who underwent microsurgical resection of vestibular schwannoma (VS) with a minimum of two available postoperative magnetic resonance imaging (MRI) scans were analyzed. Read More

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http://dx.doi.org/10.1002/lary.27945DOI Listing
February 2020
25 Reads

Cochlear Implantation in Patients With Single-sided Deafness After the Translabyrinthine Resection of the Vestibular Schwannoma-Presented at the Annual Meeting of ADANO 2016 in Berlin.

Otol Neurotol 2019 04;40(4):e461-e466

Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Düsseldorf, Düsseldorf, Germany.

Objective: To evaluate effectiveness of the cochlear implant (CI) to facilitate single-sided deafness (SSD) rehabilitation following translabyrinthine resection of the vestibular schwannoma.

Study Design: Retrospective patient review.

Setting: Single center, University hospital. Read More

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http://dx.doi.org/10.1097/MAO.0000000000002181DOI Listing
April 2019
7 Reads

Hydroxyapatite cement cranioplasty for translabyrinthine surgery: A single institution experience.

Laryngoscope 2020 01 7;130(1):206-211. Epub 2019 Mar 7.

Department of Surgery, Yale University School of Medicine, New Haven, Connecticut.

Objective: To assess complication rates in hydroxyapatite cement (HAC) cranioplasty for translabyrinthine acoustic surgery compared with historical controls.

Methods: Retrospective chart review of patients undergoing de novo translabyrinthine surgery with HAC cranioplasty without concurrent adipose tissue graft or additional material between 2010 and 2017 at a tertiary otology center.

Results: Fifty-two patients underwent HAC cranioplasty during the study period. Read More

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http://doi.wiley.com/10.1002/lary.27907
Publisher Site
http://dx.doi.org/10.1002/lary.27907DOI Listing
January 2020
47 Reads

The Feasibility of a Modified Exclusive Endoscopic Transcanal Transpromontorial Approach for Vestibular Schwannomas.

J Neurol Surg B Skull Base 2019 Feb 30;80(1):82-87. Epub 2018 Jul 30.

Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Korea.

 We evaluated the feasibility of an exclusive endoscopic transcanal transpromontorial approach (EETTA) for the treatment of small vestibular schwannomas (VSs) limited to the internal auditory canal (IAC), and introduced a modification without external auditory canal closure.  Between June 2016 and June 2017, seven patients with VS underwent surgery using a modified EETTA. Treatment outcomes, including efficacy of tumor resection, preservation of function, operation time, and quality of life (QOL), were evaluated. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1667061
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http://dx.doi.org/10.1055/s-0038-1667061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375732PMC
February 2019
38 Reads