753,649 results match your criteria Skin Therapy Letter[Journal]


Low dose of aPCC after the initial treatment in acquired haemophilia A is useful to reduce bleeding relapses: Data from the FAIR registry.

Thromb Res 2018 Dec 6;174:24-26. Epub 2018 Dec 6.

Haemophilia and Thrombosis Centre, S.Giovanni Bosco Hospital of Naples, Italy.

Background: Bypassing agents are the first line therapy in patients with acquired haemophilia A (AHA). Activated prothrombin complex concentrate (aPCC) proved to be effective as initial treatment, but 20% of patients (pts) had relapses. aPCC as short-term prophylaxis to reduce subsequent bleeds is still not clear. Read More

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December 2018
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Nanostructured lipid carriers: A potential use for skin drug delivery systems.

Pharmacol Rep 2018 Oct 11;71(1):156-166. Epub 2018 Oct 11.

Department of Pharmaceutical Technology, Medical University of Bialystok, Białystok, Poland. Electronic address:

Skin application of pharmaceutical products is one of the methods used for drug administration. The problem of limited drug penetration via topical application makes searching for safe drug carriers that will provide an expected therapeutic effect of utmost importance. Research into safe drug carriers began with liposome structures, paving the way for work with nanocarriers, which currently play a large role as drug vehicles. Read More

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October 2018
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ER stress promotes antitumor effects in BRAFi/MEKi resistant human melanoma induced by natural compound 4-nerolidylcathecol (4-NC).

Pharmacol Res 2018 Dec 11. Epub 2018 Dec 11.

Skin Biology Group, Clinical Chemistry and Toxicology Department, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil. Electronic address:

Melanoma accounts for only 4% of malignant neoplasms of the skin, but is considered the most serious because it is highly deadly. Mutations in the MAPK (Ras-Raf-MEK-ERK) pathway is closely linked to the lack of control of cell proliferation. Especially in melanoma, this pathway has become a target for the development of oncogene-targeted therapies, such as the potent inhibitors of v-Raf murine sarcoma viral oncogene homolog B (BRAFi) and mitogen-activated protein kinase kinase (MEKi). Read More

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December 2018
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Clinical and aetiological study of hand, foot and mouth disease in southern Vietnam, 2013-2015: inpatients and outpatients.

Int J Infect Dis 2018 Dec 11. Epub 2018 Dec 11.

Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Background: Hand, foot and mouth disease (HFMD) has been associated with large outbreaks among young children, including severe illness and fatality, in the Asia-Pacific Region since 1997. Severe illness is often associated with enterovirus A71 (EV-A71). Vietnam experienced a large sustained outbreak of 200. Read More

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December 2018
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Advanced chemical peels: phenol-croton oil peel.

J Am Acad Dermatol 2018 Dec 11. Epub 2018 Dec 11.

Department of Dermatology, Emory University School of Medicine, Atlanta, GA.

Once considered the gold standard for deep facial resurfacing, the classical Baker-Gordon phenol-croton oil peel has largely been replaced by formulas with lower concentrations of phenol and croton oil. The improved safety profile of deep peels has ushered in a new era in chemical peeling. Wrinkles can be improved and skin tightened with more subtle and natural results. Read More

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December 2018
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The role of the skin microbiome in atopic dermatitis.

Ann Allergy Asthma Immunol 2018 Dec 11. Epub 2018 Dec 11.

Department of Dermatology, University of California, San Diego, CA,. Electronic address:

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December 2018
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Fracture of a Transcatheter Atrial Septal Defect Occluder Device Causing Mitral Valve Perforation.

Ann Thorac Surg 2018 Dec 11. Epub 2018 Dec 11.

Department of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland; Department of Cardiovascular Surgery, University Hospital Zurich, Zurich, Switzerland.

Transcatheter atrial septal defect (ASD) device closure has gained increasing popularity over the past decades due to shorter hospital stay and the absence of skin scars. However, concern about the seriousness of device-related complications is accumulating. We report a case of device fracture in a young asymptomatic woman almost 4 years after percutaneous secundum ASD closure, resulting in mitral valve perforation. Read More

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December 2018
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Dosimetric effects of the kV based image-guided radiation therapy of prone breast external beam radiation: Towards the optimized imaging frequency.

J Appl Clin Med Phys 2018 Dec 14. Epub 2018 Dec 14.

Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.

Purpose: For prone breast treatment, daily image-guided radiation therapy (IGRT) allows couch shifting to correct breast position relative to the treatment field. This work investigates the dosimetric effect of reducing kV imaging frequencies and the feasibility of optimizing the frequency using patient anatomy or their first 3-day shifts.

Method: Thirty-seven prone breast patients who had been treated with skin marker alignment followed by daily kV were retrospectively analyzed. Read More

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December 2018
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Clinical Evaluations of a Novel Thread Lifting Regimen Using Barbed Polyglyconate Suture for Facial Rejuvenation: Analysis Using a 3-Dimensional Imaging System.

Dermatol Surg 2018 Dec 13. Epub 2018 Dec 13.

Oaro Dermatology Clinic, Seoul, Republic of Korea.

Background: Thread lifting with absorbable sutures has recently gained prominence for rejuvenating ptotic and sagging soft tissues in aging face. A barbed, delayed absorbable polyglyconate monofilament shows significantly high tensile loads with superior flexibility and elasticity.

Objective: To evaluate the safety and efficacy of novel thread lifting regimen with barbed polyglyconate suture for counteracting the descent and laxity of the aging face. Read More

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December 2018
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The "Sketch, Etch, and Sketch" Approach to Improve Accuracy and Durability of Surgical Skin Markings: Surgical Pearl.

Dermatol Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Dermatology, Geisinger, Danville, Pennsylvania.

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December 2018
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Repair of a Large Glabellar/Nasal Defect.

Dermatol Surg 2018 Dec 13. Epub 2018 Dec 13.

Mohs Micrographic and Skin Surgery PLLC, San Antonio, Texas.

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December 2018
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A Prospective Comparative Study Between Subcuticular and Sutureless Technique of Skin Closure Following External Dacryocystorhinostomy.

Ophthalmic Plast Reconstr Surg 2018 Dec 7. Epub 2018 Dec 7.

Orbit Oculoplasty Reconstructive and Aesthetic Services, Aditya Birla Sankara Nethralaya, Kolkata, India.

Purpose: To compare the cosmetic outcome of the surgical scar of external dacryocystorhinostomy by the subcuticular versus sutureless technique.

Methods: This was a prospective interventional randomized control study conducted at tertiary level hospital. Fifty patients of primary-acquired nasolacrimal duct obstruction were included in this study. Read More

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December 2018
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A Rare Cause for Recurrent Implant-Related Inflammation of Orbit: Dacryocystitis.

J Craniofac Surg 2018 Dec 13. Epub 2018 Dec 13.

Plastic, Reconstructive, and Aesthetic Surgery Department of Mersin University Medical Faculty, Mersin, Turkey.

Ultra-thin porous polyethylene has been widely preferred in orbital blow out fracture repair for many years as a safe and stable material. Delayed complications related to the implant in orbital blow out fracture repair are very rare and usually begin as a periorbital inflammation. Infections and tissue reaction to the foreign body are regarded as main causes for implant-related inflammation of which symptoms may vary among the patients and may involve subacute and chronic eyelid swelling, skin redness, pain, conjunctival injection, proptosis, and acute orbital inflammation. Read More

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December 2018
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Nonexpanded Prefabricated Anterior Perforator of Transverse Cervical Artery Flap for Full Facial Reconstruction.

J Craniofac Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Plastic and Aesthetic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology (HUST), Hubei, China.

Background: Prefabricated flap is an important technique to reconstruct facial skin defects. There is no any procedure for full facial reconstruction, and we are the first one to accomplish it.

Methods: Instead of the traditional supraclavicular island flap, we choose nonexpanded flap pedicled by the anterior perforator of transverse cervical artery (ap-TCA) to repair the whole facial deformity. Read More

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December 2018
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[Functional parotid surgery for removal of benign parotid tumors].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1810-1812

Department of Stomatology, Tongji Hospital, Tongji University.

To evaluate the effect of the application of functional parotid surgery for removal of benign parotid tumors and the prevention of Frey syndrome. One hundred and fifty-six cases with benign tumor were underwent functional regional parotidectomy. All tumors were smaller than 4 cm in diameter. Read More

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December 2018
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[Observation on pollinosis with vegetable food allergy].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1779-1783

Department of Allergy, Beijing Shijitan Hospital, Affiliated to Capital Medical University, Beijing, 100038, China.

To investigate the incidence of plant food allergy in patients with pollinosis and the effect of food allergens on the clinical symptoms of pollinosis patients. A total of 40 patients with pollinosis and food allergy attended to the allergy Department of Duolun People's Hospital of Inner Mongolia were accepted skin prick test of inhaled allergens while the rhino conjunctivitis quality of life questionnaire(RQLQ) were also completed. The patients were divided into A and B groups randomly. Read More

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December 2018
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[Different phenotypes in patients with chronic sinusitis with bilateral nasal polyps].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1774-1778

Department of Otolaryngology Head and Neck Surgery, Nanjing General Hospital of PLA.

To investigate the clinical features of patients with chronic sinusitis with bilateral nasal polyps. The data of 134 patients with chronic sinusitis with bilateral nasal polyps were analyzed, retrospectively. Based on the results of the histopathological examination, patients were divided into eosinophilic chronic sinusitis with bilateral nasal polyps(ECRSwBNP) group and noneosinophilic chronic sinusitis with bilateral nasal polyps(nonECRSwBNP) group. Read More

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December 2018
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[Reconstruction of scarring pharyngeal stenosis with forearm free flap:a case report].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Sep;32(18):1434-1435

A 33-year-old man presented with recurrent oral ulcers for more than 10 years,accompanying dyspnea and dysphagia for 1 year and aggravate for 1 month.Physical examination:pharyngeal cavity stenosis,mucous retention, epiglottis was extruded into the infant type. Electronic laryngoscope:Epiglottis curl,bilateral pyriform sinus disappeared. Read More

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September 2018
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[Prevalence of allergy in children with acute rhinosinusitis].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Sep;32(18):1377-1382

Department of Otolaryngology, the Second Affiliated Hospital of Wenzhou Medical University,Wenzhou, 325000, China.

To explore the prevalence of allergy in patients with acute rhinosinusitis (ARS) and evaluate the severity of symptoms in ARS children with or without allergy.Two hundred and seven children (4-12 years of age) with ARS and 85 children of control group were included in our research from June, 2016 to January, 2018. We use questionaire to collect the basic information of pediatric patients. Read More

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September 2018
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[The sensitization feature of artemisia allergy and the diagnosis value of skin prick test].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(24):1860-1864

Department of Allergy, Beijing Shijitan Hospital, Capital Medical University, Beijing, 100038, China.

The purpose of this study was to explore the sensitization feature of artemisia allergy and to assess the diagnostic value of skin prick test(SPT) compared with specific IgE(sIgE) test. One hundred and fifty-one patients with typical rhino-conjunctivitis symptoms during pollen season were enrolled and general information was recorded in this study. All subjects received SPT and sIgE test of artemisia allergen. Read More

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December 2018
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[The development of laboratory diagnostic of leprosy using polymerase chain reaction].

Klin Lab Diagn 2018 ;63(1):55-59

DNA-Technology LLC, 115478, Moscow, Russia.

The purpose of study is to develop techniques of laboratory diagnostic of leprosy on the basis of polymerase chain reaction. The techniques were worked through such as extraction of DNA from various clinical material (bioptates and scarifcate of skin, scrapes from mucous surface of nose and trophic ulcers, blood serum). The systems of oligonucleotides were constructed to 16S pRNA and probe for identifcation of Mycobacterium leprae in real-time format for amplifer DT-96 ("The DNA-Technology", Russia). Read More

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January 2018
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Suprathreshold laser injuries in excised porcine skin for millisecond exposures at 1070 nm.

J Biomed Opt 2018 Dec;23(12):1-11

711th Human Performance Wing, Airman Systems Directorate, Bioeffects Division, Optical Radiation Bio, United States.

Skin injury response to near-infrared (NIR) laser radiation between the minimum visible lesion threshold and ablation onset is not well understood. This study utilizes a 1070-nm diode-pumped Yb-fiber laser to explore the response of excised porcine skin to high-energy exposures in the suprathreshold injury region without inducing ablation. Concurrent high-speed videography is employed to determine a dichotomous response for three progressive damage categories: observable surface distortion, surface bubble formation due to contained intracutaneous water vaporization, and surface bubble rupture during exposure. Read More

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December 2018
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Review of light parameters and photobiomodulation efficacy: dive into complexity.

J Biomed Opt 2018 Dec;23(12):1-17

Massachusetts General Hospital, Wellman Center for Photomedicine, Boston, Massachusetts, United States.

Photobiomodulation (PBM) therapy, previously known as low-level laser therapy, was discovered more than 50 years ago, yet there is still no agreement on the parameters and protocols for its clinical application. Some groups have recommended the use of a power density less than 100  mW/cm2 and an energy density of 4 to 10  J/cm2 at the level of the target tissue. Others recommend as much as 50  J/cm2 at the tissue surface. Read More

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December 2018
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Evaluation and Predictors for Nasogastric Tube Associated Pressure Ulcers in Critically Ill Patients.

Isr Med Assoc J 2018 Dec;20(12):731-736

Department of Intensive Care Medicine, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Background: Nasal device-related pressure ulcers are scarcely addressed in the literature.

Objectives: To assess the prevalence and severity of cutaneous and mucosal nasogastric tube (NGT)-associated pressure ulcers (PU) in critically ill patients and to define predictors for their formation.

Methods: A single center observational study of intensive care unit patients with a NGT for more than 48 hours was conducted. Read More

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December 2018
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A homozygous MITF mutation leads to familial Waardenburg syndrome type 4.

Am J Med Genet A 2018 Dec 14. Epub 2018 Dec 14.

Department of Otolaryngology - Head and Neck Surgery, The Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Waardenburg syndrome (WS) is a genetic disorder characterized by hearing loss and pigmentary abnormalities with variable penetrance. Though heterozygous mutations in MITF are a major cause for Waardenburg syndrome type 2 (WS2), homozygous mutations in this gene and the associated phenotype have been rarely characterized. In this study, we identified a novel p. Read More

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December 2018
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Relief of intractable pruritus with romidepsin in patients with cutaneous T-cell lymphoma: a series of 4 cases.

Dermatol Ther 2018 Dec 14:e12804. Epub 2018 Dec 14.

Cutaneous Lymphoma Program, Toni Stephenson Lymphoma Center, City of Hope, Duarte, CA.

Cutaneous T-cell lymphomas (CTCL) are a relatively rare and heterogeneous group of non-Hodgkin lymphomas that typically present in the skin. The majority of patients with CTCL experience pruritus, which can interfere with daily activities, significantly impact quality of life, and is typically uncontrolled by standard anti-itch therapies. Several lymphoma treatments have reported anti-pruritic effects including romidepsin, a potent class 1 selective histone deacetylase inhibitor approved for the treatment of patients with CTCL who have had at least 1 prior systemic therapy. Read More

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December 2018
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Wishing to be perceived as a capable and resourceful person - A qualitative study of melanoma patients' experiences of the contact and interaction with healthcare professionals.

J Clin Nurs 2018 Dec 14. Epub 2018 Dec 14.

Department of Nursing, Umeå University, SE -901 85, Umeå, Sweden.

Aims And Objectives: We aimed to explore patients' experiences of contact and interaction with healthcare professionals (HCPs) during the diagnostic process of melanoma.

Background: In Sweden, most patients with suspected skin lesions seek care at the primary level of services in the first instance. Previous research describe the diagnostic process as a complex journey with uncertainty. Read More

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December 2018
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Nonmelanoma skin cancer of the head and neck region in solid organ transplant recipients.

Head Neck 2018 Dec 14. Epub 2018 Dec 14.

Department of Otolaryngology, Head and Neck Surgery, Rabin Medical Center, Petach Tikva, Israel.

Background: Nonmelanoma skin cancers (NMSC) are the most common malignancies in solid organ recipients. We investigated the incidence, clinical features, and outcome of solid organ recipients with NMSC of the head and neck.

Methods: A retrospective chart review was conducted for solid organ recipients who were treated from 1992 to 2015 and who developed NMSC of the head and neck. Read More

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December 2018
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PROTECT - Trial: A cluster RCT to study the effectiveness of a repositioning aid and tailored repositioning to increase repositioning compliance.

J Adv Nurs 2018 Dec 14. Epub 2018 Dec 14.

Skin Integrity Research Group (SKINT), University Centre for Nursing and Midwifery, Department of Public Health and Primary Care, Ghent University, Ghent, Belgium.

Aim: To study the effectiveness of tailored repositioning and a turning and repositioning system on: (1) nurses' compliance to repositioning frequencies; (2) body posture of patients after repositioning; (3) incidence of pressure ulcers and incontinence-associated dermatitis; (4) nurses' and patients' preferences, comfort and acceptability; and (5) budget impact.

Background: Patient-tailored systematic repositioning is key in pressure ulcer prevention. To date, a clinical decision-making tool is lacking and compliance to pressure ulcer prevention guidelines is low. Read More

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December 2018
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Induction of fat apoptosis by a non-thermal device: Mechanism of action of non-invasive high-intensity electromagnetic technology in a porcine model.

Lasers Surg Med 2018 Dec 14. Epub 2018 Dec 14.

Veterinary Research Institute, Brno, Czech Republic.

Objectives: While controlled thermal changes in subcutaneous tissue have been used to trigger apoptosis of fat cells and have been proven clinically efficacious, another mechanism of electromagnetic stress suggests that fat apoptosis could be achieved by a non-thermal manner as well. This animal model study investigates the use of a non-invasive high-intensity magnetic field device to induce apoptosis in fat cells.

Methods: Yorkshire pigs (N = 2) received one treatment (30 minutes) in the abdominal area using a High-Intensity Focused Electromagnetic (HIFEM) device. Read More

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December 2018
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Dermapen in the treatment of wrinkles in cigarette smokers and skin aging effectively.

J Cosmet Dermatol 2018 Dec;17(6):1200-1204

Department of Dermatology & Venereology, Medical School, Zagazig University, Cairo, Egypt.

Skin aging is a complex biological process that arises from two basic processes: intrinsic aging (influenced by genetics factors, cellular metabolism, hormone, and metabolic processes) and extrinsic aging caused by chronic light exposure, pollution, ionizing radiation, chemicals, toxins (Expert Opin Biol Ther. 2008;8:393). Intrinsic aging called also chronological aging is observed in sun-protected skin of elderly persons. Read More

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December 2018
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Human native endocarditis caused by Streptococcus canis-a case report.

APMIS 2019 Jan;127(1):41-44

Centre for Cardiovascular Surgery and Transplantation, Brno, Czech Republic.

We report a very rare case of Streptococcus canis native infective endocarditis in a 73-year-old woman living in close contact with her dog. Her echocardiography showed large calcifications in the mitral annulus, massive regurgitation below the posterior leaflet, and adjacent vegetation. Blood culture was positive for Streptococcus Lancefield group G. Read More

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January 2019
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Evaluation of the efficacy of granulocyte and monocyte adsorption apheresis on skin manifestation and joint symptoms of patients with pustulotic arthro-osteitis.

J Dermatol 2018 Dec 14. Epub 2018 Dec 14.

Department of Dermatology, Tokyo Medical University, Tokyo, Japan.

Pustulotic arthro-osteitis, occasionally complicated with palmoplantar pustulosis, affects patients' activities of daily living. Granulocyte and monocyte adsorption apheresis selectively removes activated granulocytes and monocytes by means of extracorporeal circulation. Although the efficacy of granulocyte and monocyte adsorption apheresis in the treatment of generalized pustular psoriasis has been proved, very few reports have assessed its efficacy in the treatment of palmoplantar pustulosis and pustulotic arthro-osteitis. Read More

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December 2018
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Polymorphic eruption of pregnancy in Mexico.

Int J Dermatol 2018 Dec 13. Epub 2018 Dec 13.

Facultad de Medicina, Human Anatomy Department, Universidad Autonoma de Nuevo Leon, Monterrey, Mexico.

Background: Currently, the exact incidence of Polymorphic Eruption of Pregnancy (PEP) in the Mexican population is unknown. PEP tends to manifest in the abdomen, primarily in the stretch marks caused by distension. It is characterized by severely pruritic urticarial-like papules that converge in plaques, extending to the buttocks and proximal thighs. Read More

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December 2018
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Anti-psoriatic effect of myeloid-derived suppressor cells on imiquimod-induced skin inflammation in mice.

Scand J Immunol 2018 Dec 13:e12742. Epub 2018 Dec 13.

Pharmicell Co, Ltd, 484, Dunchon-daero, Jungwon-gu, Seongnam, Gyeonggi-do, Korea.

Myeloid-derived suppressor cells (MDSCs) play an important role in controlling the immune response against cancer and in suppression of autoimmunity and allergic inflammation. However, the beneficial effects of MDSCs on the experimental mouse model of psoriasis have not been reported. Therefore, we investigated the anti-psoriatic effect of MDSCs on IMQ-induced skin inflammation in mice and explored the mechanisms involved. Read More

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December 2018
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Design and validation of a "Peristomal Lesion Scale" for peristomal skin assessment.

Int Wound J 2018 Dec 13. Epub 2018 Dec 13.

Department of Molecular Medicine, University of Padova, Padova, Italy.

Many people in Italy undergo ostomy because of illness, and this can have negative psychological and physical effects. It is estimated that 15%-43% of ostomates suffer from skin complications in the peristomal area. During their life, many ostomates experience at least one peristomal lesion, and they turn to stomal therapy centres where trained nurses provide patient care and manage skin complications. Read More

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December 2018
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Metallosupramolecular Photonic Elastomers with Self-Healing Capability and Angle-Independent Color.

Adv Mater 2018 Dec 13:e1805496. Epub 2018 Dec 13.

Key Lab of Materials Chemistry for Energy Conversion and Storage of Ministry of Education (HUST), School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Wuhan, 430074, P. R. China.

Photonic elastomers that can change colors like a chameleon have shown great promise in various applications. However, it still remains a challenge to produce artificial photonic elastomers with desired optical and mechanical properties. Here, the generation of metallosupramolecular polymer-based photonic elastomers with tunable mechanical strength, angle-independent structural color, and self-healing capability is reported. Read More

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December 2018
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Silk fibroin hydrogels for potential applications in photodynamic therapy.

Biopolymers 2018 Dec 13:e23245. Epub 2018 Dec 13.

Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, Brazil.

In this study, we prepared translucid hydrogels with different concentrations of silk fibroin, extracted from raw silk fibers, and used them as a matrix to incorporate the photosensitizer 5-(4-aminophenyl)-10,15,20-tris-(4-sulphonatophenyl) porphyrin trisodium for application in photodynamic therapy (PDT). The hydrogels obtained were characterized by rheology, spectrophotometry, and scattering techniques to elucidate the factors involved in the formation of the hydrogel, and to characterize the behavior of silk fibroin (SF) after incorporating of the porphyrin to the matrix. The rheology results demonstrated that the SF hydrogels had a shear thinning behavior. Read More

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December 2018
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Definitive radiotherapy versus Mohs surgery for early stage nonmelanoma skin cancers: a multi-institutional retrospective comparison of local recurrence.

Int J Dermatol 2018 Dec 13. Epub 2018 Dec 13.

Department of Dermatology, Drexel University College of Medicine, Philadelphia, PA.

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December 2018
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Effect of cosmetic chemical preservatives on resident flora isolated from healthy facial skin.

J Cosmet Dermatol 2018 Dec 12. Epub 2018 Dec 12.

Beijing Key Lab of Plant Resources Research and Development, College of Science, Beijing Technology and Business University, Beijing, China.

Background/aims: Healthy skin harbors numerous microbes known to maintain its health and prevent attacks from external pathogens. The influence of chemical preservatives commonly used in cosmetic products on facial resident flora remains poorly characterized. In this study, we aimed to investigate the antibacterial activity of five such preservatives on in vitro cultivated skin-resident bacteria. Read More

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December 2018
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What's new in the treatment of atopic dermatitis?

Dermatol Ther 2018 Nov 22:e12787. Epub 2018 Nov 22.

Department of Health Sciences, Unit of Dermatology, "Magna Graecia" University, Catanzaro, Italy.

Atopic dermatitis (AD) is a pruritic, chronic and inflammatory skin disease, with an usual onset in the pediatric age. Several drugs are used in the treatment of this skin disease. Drugs as steroid, calcineurin inhibitors, and moisturizing creams are widely used in the treatment of this disease but often patients are not satisfied with the obtained results. Read More

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November 2018
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Cracking and Fracture Properties of Potato (Solanum tuberosum L.) Tubers and Their Relation to Dry Matter, Starch, and Mineral Distribution.

J Sci Food Agric 2018 Dec 13. Epub 2018 Dec 13.

Department for Crop Sciences, Division Quality of Plant Products, Carl-Sprengel-Weg 1, 37075 Göttingen, University of Göttingen, Germany.

Background: Potato disorders lead to significant reductions in the yield and quality of marketable tubers. Thumbnail cracks are physiological tuber skin disorders that can significantly affect the tuber appearance and, hence, the overall quality. The aim of the study was to characterize fracture properties of the tuber skin. Read More

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December 2018
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Evidence-based skin care in preterm infants.

Pediatr Dermatol 2018 Dec 12. Epub 2018 Dec 12.

Department of Dermatology, University of California, San Diego School of Medicine, San Diego, California.

Most guidelines on neonatal skin care emphasize issues pertaining to healthy, term infants. Few address the complex task of skin barrier maintenance in preterm, very preterm, and extremely preterm infants. Here, we provide an evidence-based review of the literature on skin care of preterm neonates. Read More

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December 2018
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Brown adipose tissue thermogenesis in polycystic ovary syndrome.

Clin Endocrinol (Oxf) 2018 Dec 12. Epub 2018 Dec 12.

Department of Physiology, Monash University, Melbourne, Victoria, Australia.

Objective: Polycystic ovary syndrome (PCOS) is associated with increased obesity with a greater propensity to weight gain and a lack of sustainable lifestyle interventions. Altered brown adipose tissue (BAT) thermogenesis is a potential contributor to obesity in PCOS. BAT activity and modulation has not been studied in PCOS. Read More

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December 2018
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Canine non-epitheliotropic CD4-positive cutaneous T-cell lymphoma: a case report.

Vet Med Sci 2018 Dec 12. Epub 2018 Dec 12.

Synergy Animal General Hospital, Kawaguchi, Saitama, Japan.

A 5-year-old, spayed female French Bulldog presented with multiple papules on the skin of the scapular area. Histopathological examination of punch biopsy samples revealed dense infiltration of small lymphoid cells in the superficial dermis and in areas surrounding hair follicles. Immunohistochemical analysis indicated that these cells were positive for CD3, CD4, and TCRαβ, but negative for CD1c, CD8α, CD8β, CD11c, CD20, CD45RA, CD90, MHC-II, and TCRγδ. Read More

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December 2018
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African biogeographical ancestry, atopic and non-atopic asthma and atopy: A study in Latin American children.

Pediatr Pulmonol 2018 Dec 11. Epub 2018 Dec 11.

Institute of Collective Health, Federal University of Bahia, Salvador, Bahia, Brazil.

Background: Genetic variants underlying African ancestry have been suggested be implicated in the ethnic-racial inequalities reported for asthma and allergies.

Objectives: To investigate the association between individual African ancestry and asthma symptoms, atopic and non-atopic asthma, and atopy in children.

Methods: A cross-sectional study encompassing 1190 individuals was conducted. Read More

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December 2018
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Doulas in the Operating Room: An Innovative Approach to Supporting Skin-to-Skin Care During Cesarean Birth.

J Midwifery Womens Health 2018 Dec 12. Epub 2018 Dec 12.

Introduction: Skin-to-skin care (SSC) immediately after birth is recommended for all women and their newborns. Barriers to SSC after cesarean birth lead to delays in initiation of this practice. The purpose of this quality improvement project was to implement an innovative approach with volunteer doulas to support initiation of SSC after cesarean for all clients. Read More

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December 2018
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A Freestanding Stretchable and Multifunctional Transistor with Intrinsic Self-Healing Properties of all Device Components.

Small 2018 Dec 12:e1803939. Epub 2018 Dec 12.

The Department of Chemical Engineering, Technion - Israel Institute of Technology, Haifa, 3200003, Israel.

A flexible and stretchable field-effect transistor (FET) is an essential element in a number of modern electronics. To realize the potential of this device in harsh real-world conditions and to extend its application spectrum, new functionalities are needed to be introduced into the device. Here, solution-processable elements based on carbon nanotubes that empower flexible and stretchable FET with high hole-mobility (µ ≈ 10 cm V s ) and relatively low operating voltages (<8 V) and that retain self-healing properties of all FET components are reported. Read More

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December 2018
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Tinea faciei starting at day two of life.

Pediatr Dermatol 2018 Dec 11. Epub 2018 Dec 11.

Department of Dermatology, Children's of Alabama, Birmingham, Alabama.

Dermatophyte infections are exceedingly rare in neonates, possibly due to the thin stratum corneum and high sebum content of neonatal skin. Only a handful of cases of tinea faciei have been reported in neonates, with the majority of reports occuring in India. Here, we report what to our knowledge is the earliest reported presentation of tinea faciei in the United States. Read More

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December 2018
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Atypical actinobacillosis affecting hind limbs and lungs in a single beef cattle herd.

J Vet Intern Med 2018 Dec 12. Epub 2018 Dec 12.

Clinic for Ruminants, Nantes, France.

Actinobacillosis usually is a sporadic infection that affects the tongue in cattle ("wooden tongue") with possible spread to the digestive tract. Two 4-year-old Rouge-des-Prés cows from a single French beef herd were referred for chronic (2-6 months) swelling and cutaneous nodules in the distal hind limbs. In addition to cutaneous signs, physical examination disclosed cachexia, lameness, lymphadenitis of the hind limbs, and pneumonia in both cows. Read More

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December 2018
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