Search Our Scientific Publications & Authors

J Cosmet Dermatol 2020 Jun 5. Epub 2020 Jun 5.

Derma- Care skin and cosmetology Centre, Mangalore, India.

Fractional CO laser is an accepted and preferred form of treatment for resurfacing of all scars- accident scars, burn scars and acne scars. In 2004, Manstein et al. introduced the concept of fractional photothermolysis. Read More

Lasers Surg Med 2020 Jan 14. Epub 2020 Jan 14.

Institute of Biomedical Optics, University of Luebeck, Luebeck, 23562, Germany.

Background And Objectives: A recent generation of 5,500 nm wavelength carbon monoxide (CO) lasers could serve as a novel tool for applications in medicine and surgery. At this wavelength, the optical penetration depth is about three times higher than that of the 10,600 nm wavelength carbon dioxide (CO ) laser. As the amount of ablation and coagulation is strongly influenced by the wavelength, we anticipated that CO lasers would provide extended coagulation zones, which could be beneficial for several medical applications, such as tissue tightening effects after laser skin resurfacing. Read More

J Drugs Dermatol 2019 Nov;18(11):174-1176

Porokeratosis is a rare disorder of epidermal keratinization that encompasses several clinical forms, characterized by erythematous, annular plaques with an atrophic center and hyperkeratotic ridge-like border. The histopathological hallmark of porokeratosis is the cornoid lamella, a thin column of parakeratotic corneocytes embedded within the stratum corneum. There is no standard treatment regimen for porokeratosis. Read More

J Craniofac Surg 2020 Mar/Apr;31(2):e140-e144

Huseyin Guner Aesthetic Surgery Clinic, Istanbul, Turkey.

Background: More preservative approaches are being adopted in periorbital surgery each day. To avoid the possible complications of transcutaneous and transconjunctival blepharoplasty, the author has developed the safe and simple "Percutaneous Lower Blepharoplasty" technique, which he has been performing since 2008. The technique consists of the removal and transfer of lower orbital fat pads through 4-mm skin incisions with minimal dissection. Read More

Dermatol Ther 2019 11 7;32(6):e13084. Epub 2019 Oct 7.

Department of Dermatology, The Affiliated Hospital of North Sichuan Medical College, Nanchong, China.

Fractional ablative carbon dioxide laser resurfacing is a frontline treatment for acne scars. It creates multiple microscopic treatment zones to accelerate the collagen formation and the healing process of reepithelialization, according the principle of fractional photothermolysis. At present, the fractional CO laser with a wavelength of 10,600 nm is commonly used in the field of cosmetology and clinical therapies for various skin diseases, and it can effectively improve skin regeneration and scar formation. Read More

Facial Plast Surg 2019 Jun 12;35(3):248-255. Epub 2019 Jun 12.

Department of Otolaryngology - Head and Neck Surgery, Rutgers New Jersey Medical School, Summit, New Jersey.

Laser technology continues to increase in popularity and expand treatment options for patients with common but challenging skin conditions including facial telangiectasias, facial aging, striae distensae, and acne scars. Facial telangiectasias have been estimated to occur in tens of millions of people worldwide. The 585-nm laser was the first to follow the principle of selective photothermolysis for the treatment of cutaneous vascular lesions, but it caused significant postoperative purpura. Read More

J Dermatolog Treat 2019 Jul 5:1-8. Epub 2019 Jul 5.

a Department of Dermatology, Venereology and Andrology , Assiut University Hospital , Assiut , Egypt.

To explore the impact of using topical stem cell-conditioned medium (SC-CM) after fractional carbon dioxide laser (FCL) combined FCL and platelet-rich plasma (PRP) or FCL alone in treatment of atrophic acne scars. Thirty-three patients were randomly divided into two split-face groups. Group I (  =  17) received FCL plus topical SC-CM on one side or FCL plus saline on the other. Read More

Skin Res Technol 2019 Nov 22;25(6):805-809. Epub 2019 May 22.

Terahertz Science and Technology Center (C2T2) and Terahertz Science and Technology National Laboratory (LANCYTT), Universidad Autónoma de San Luis Potosí, San Luis Potosí, México.

Background: Ablative fractional laser surgery is a common technique for treating acne scars. However, an in vivo and noninvasive analysis of the histologic variations between acne skin and the resulting resurfaced skin is needed in order to evaluate the wound healing process of the scars induced by the ablative fractional laser surgery.

Materials And Methods: Nine patients with acne scars underwent a single treatment with a CO ablative fractional laser surgery. Read More

J Cosmet Laser Ther 2019 7;21(6):309-315. Epub 2019 May 7.

Cosmetic Surgeon at Villa Salaria, private hospital , Rome , Italy.

: The goal of our prospective study was to assess the efficacy of the topical Platelet-rich plasma on reducing superficial perioral wrinkles and restoring the dermal matrix. : 50 women with moderate to severe perioral wrinkles were treated on the perioral area by a single session of fractional CO2 laser skin resurfacing plus intradermal injection of prp. 25 patients (group 1) applied topically prp twice a day for 12 weeks as post laser treatment. Read More

Dermatol Ther (Heidelb) 2019 Jun 30;9(2):321-326. Epub 2019 Apr 30.

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Introduction: Keloids are challenging to treat due to their inadequate response to treatment and high recurrence rate. Intralesional triamcinolone acetonide (TAC) injection with or without 5-fluorouracil (5FU) is considered the first-line treatment for keloids. Three significant disadvantages of intralesional injections are the pain associated with the procedure, the uneven topography, and epidermal atrophy. Read More

J Cosmet Dermatol 2019 Dec 4;18(6):1751-1757. Epub 2019 Apr 4.

Department of Pediatrics, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, Thailand.

Introduction: Fractional carbon dioxide (FrCO ) laser is effective for atrophic acne scar treatment, but unavoidable downtime. Meanwhile, postoperative topical steroid decreases the downtime, yet still possibly increases other steroid side effects.

Objective: To evaluate the efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese (experimental cream) versus 0. Read More

J Drugs Dermatol 2019 Mar;18(3):274-275

The use of full-thickness skin grafts (FTSG) in facial reconstruction during dermatologic surgery is well-established. Surgical sites that commonly receive a skin graft include the scalp, nose and ear Read More

Cutan Ocul Toxicol 2019 Sep 20;38(3):274-278. Epub 2019 Apr 20.

a Department of Dermatology and Allergology, Medical Faculty, RWTH Aachen University , Aachen , Germany.

Laser therapy with an ablative CO laser is a prominent treatment option for photo-damaged skin. The healing process and therefore the success of a laser can be supported by an appropriate postoperative treatment of the laser-treated skin. : The effect of a dexpanthenol-containing ointment with petroleum jelly on wound healing after fractional ablative CO laser therapy of photo-damaged skin. Read More

Lasers Med Sci 2019 Aug 4;34(6):1125-1135. Epub 2019 Jan 4.

Ophthalmology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.

Fractional CO laser rejuvenation of scars offers a high safety profile. Laser marks usually disappear clinically within 1 week. The authors observed occasional persistence of the laser marks on the scar surface. Read More

Facial Plast Surg 2018 Dec 28;34(6):624-630. Epub 2018 Dec 28.

Department of Plastic Surgery, King Edward VII's Hospital, London, Greater London, United Kingdom.

Facelift surgery is a popular treatment but exhibits high variation among practitioners in terms of both core technique and adjunctive measures. This review identified significant evidence addressing the role of pre-infiltration, drains, fat grafting, fibrin tissue adhesives, hilotherapy, and other miscellaneous adjuncts. Based on the authors' assessment of the current literature, there is reasonable supportive evidence for pre-infiltration, fat grafting and laser skin resurfacing, which appear to be safe and effective in appropriately selected patients. Read More

Plast Reconstr Surg 2019 01;143(1):64-74

Dallas, Texas; and Miami, Fla. From the Department of Plastic Surgery, University of Texas Southwestern Medical Center; private practice; and Dallas Plastic Surgery Institute.

Background: Use of nonsurgical skin rejuvenation has grown over the past two decades. This has led to an increase in ablative and nonablative resurfacing devices. Moderate to heavy perioral rhytides require an ablative laser to maximize results. Read More

J Drugs Dermatol 2018 11;17(11):1178 - 1182

Purpose: Fractionated carbon dioxide (CO2) laser resurfacing uses fractional photothermolysis with an ablative 10,600-nm wavelength for treatment of rhytides and photodamage. Although associated with reduced side effect profile from traditional ablative lasers, fractionated lasers can lead to significant erythema, edema, crusting, and exudation for 14 days. Post-care includes regular distilled water soaks and healing ointment. Read More

J Drugs Dermatol 2018 11;17(11):1157 - 1162

OBJECTIVE: The aim of this study was to evaluate the incidence of adverse effects following laser skin resurfacing with the microablative carbon dioxide (CO2) laser system (SmartXide DOT; DEKA, Calenzano, Italy). METHODS: A retrospective chart review was performed. Data was collected for DOT laser procedures performed at three clinical centers from 2008-2014. Read More

J Oral Maxillofac Surg 2019 Feb 27;77(2):411.e1-411.e8. Epub 2018 Oct 27.

Lecturer, Department of Oral & Maxillofacial Surgery, MGM Dental College & Hospital, Navi Mumbai, India.

Purpose: The purpose was to evaluate the clinical outcomes of laser skin resurfacing using an ultra-pulse carbon dioxide (CO) laser and manual dermabrasion with a medium-grit drywall sand screen for scar revision in adults with Fitzpatrick skin type III to V.

Materials And Methods: A total of 20 postsurgical and post-traumatic scars in individuals with Fitzpatrick skin type III to V were included in this study. Preoperative evaluation of the scars was performed by 3 blinded observers using the Manchester scar rating scale. Read More

Facial Plast Surg Clin North Am 2018 Nov 16;26(4):439-446. Epub 2018 Aug 16.

Department of Otolaryngology-Head and Neck Surgery, Weill Cornell Medicine, 1305 York Avenue, Fifth Floor, New York, NY 10021, USA. Electronic address:

Platelet preparations, including platelet-rich plasma and platelet-rich fibrin matrix, have been used to improve wound healing, recovery time, and cosmetic outcomes for facial rejuvenation. Bioactive growth factors released from platelets are the putative agents in producing a reparative tissue reaction in the treated area. Different methods of processing the patients' blood will yield different types of platelet preparations with different components and properties, and it is important to understand these differences and their potential implications. Read More

J Cosmet Laser Ther 2019 10;21(4):217-224. Epub 2018 Sep 10.

Department of Dermatology, the First Affiliated Hospital of Nanjing Medical University , Nanjing , Jiangsu , China.

Fractional carbon dioxide laser resurfacing (FxCR) is a routine treatment of Dermatology while many patients suffered the damage of skin barrier function after FxCR. To evaluate the benefits of antimicrobial peptides (AMPs) and hyaluronic acid (HA) compound mask on wound healing after FxCR on human and mouse skin. Twenty-four subjects were treated with FxCR on the bilateral cheeks. Read More

Aesthetic Plast Surg 2019 02 21;43(1):213-220. Epub 2018 Aug 21.

Department of Plastic and Reconstructive Surgery, Kangnam Sacred Heart Hospital, College of Medicine, Hallym University, 1 Singil-ro, Yeongdeungpo-gu, Seoul, 07441, Republic of Korea.

Purpose: A linear surgical scar, when located in the head and neck region, can be a significant cosmetic concern. Laser skin resurfacing with a fractional laser and a pulsed dye laser has been proven to be useful for treating such scars. As alternatives, we used a classic ablative CO laser in continuous mode with a 1-mm spot size and a 595-nm Nd:YAG laser. Read More

Lasers Med Sci 2019 Mar 3;34(2):343-351. Epub 2018 Aug 3.

Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Pran-nok Road, Bangkok, 10700, Thailand.

Therapy with light-emitting diodes (LED) has been associated with the reduction of erythema and accelerated wound healing. LED phototherapy has been used in various clinical practices including post-laser wound healing enhancement. Fractional laser resurfacing is one of the popular dermatological procedures; however, the duration and degree of downtime may limit daily life activity and studies on the effect of LED low-level light therapy (LED-LLLT) on post-ablative laser wound care are still limited. Read More

J Cosmet Laser Ther 2019 18;21(3):145-146. Epub 2018 Jul 18.

a Department of Dermatology , Habib Thameur Hospital , Tunis , Tunisia.

Fractional photothermolysis was initially introduced by Manstein in 2004 .Fractional CO2 laser technology introduced has allowed physicians to obtain good cosmetic results with a lower rate of complications than non-fractionated ablative laser treatment. However, adverse effects may still occur. Read More

J Drugs Dermatol 2018 Jul;17(7):796-799

Background And Objective: Misperceptions have persisted regarding scanning full-field erbium laser that have caused it to be overshadowed by fractional ablative resurfacing. This can lead to sub-optimally treating the periocular and perioral skin. Our report describes the utility of a combined approach of fractional ablative CO2 with full-field erbium ablation for full face rejuvenation. Read More

J Cosmet Dermatol 2018 Oct 29;17(5):756-761. Epub 2018 Jun 29.

Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Background: Epidermal growth factor (EGF) is one of the important peptides in wound healing process. The effects of EGF have been increasingly studied in various types of ulcers. However, data on postablative laser resurfacing wound is still limited. Read More

Lasers Surg Med 2018 12 17;50(10):1010-1016. Epub 2018 Jun 17.

Department of Dermatology, University Medical Centre Regensburg, 93042, Regensburg, Germany.

Background: Fractional ablative resurfacing is frequently used for treating atrophic and acne scars as well as for the early improvement of scars after surgery. No evidence-based clinical data on improving the appearance of skin grafts by fractional CO -laser resurfacing have been available so far.

Objectives: The primary outcome parameter was the adaptation of the skin graft to the surrounding skin 2, 6, and 12 months after the second laser treatment. Read More

Lasers Surg Med 2018 12 8;50(10):980-986. Epub 2018 Jun 8.

Department of Ophthalmology, Leiden University Medical Center, Leiden, The Netherlands.

Background And Objectives: A 36-year-old woman underwent CO laser resurfacing for periocular rhytides using protective stainless steel Cox II ocular shields. Immediately after the treatment, corneal lesions were seen in both eyes. The left eye subsequent developed corneal ulceration and scarring, a deformed iris, cataract, and lower eye lashes showing signs of acute burns. Read More

Lasers Med Sci 2018 Sep 30;33(7):1485-1491. Epub 2018 Apr 30.

Student Hospital, Cairo, Egypt.

Pseudo-acanthosis nigricans is a common dermatological disorder that is usually difficult to treat secondary to maceration of the skin from excessive sweating, obesity, or associated with endocrine disorders. Fractional photothermolysis and chemical peeling have been reported to improve the condition. To determine whether fractional CO laser resurfacing or glycolic acid peel is more effective and safe option for therapy. Read More

Int J Dermatol 2018 Apr 12;57(4):480-487. Epub 2018 Feb 12.

Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Pathumwan, Bangkok, Thailand.

Proven as effective acne scar treatment, ablative fractional carbon dioxide (AFCO ) laser requires post-laser wound healing care. MAS063DP is a multicomponent nonsteroidal anti-inflammatory moisturizer for effective post-laser treatment. This study compares the efficacy of MAS063DP and 0. Read More

J Cosmet Laser Ther 2018 Jun 13;20(3):168-178. Epub 2017 Dec 13.

b Department of Plastic Surgery, Southern Medical University , Tonghe , Guangzhou , China.

Objective: Laser skin resurfacing (LSR) has been used for facial rejuvenation for the last 20 years. Posttreatment care after LSR is essential to decrease the risk of complications. Currently, no unified standards or criteria exist for invasive LSR posttreatment care. Read More

J Drugs Dermatol 2017 Nov;16(11):1085-1090

BACKGROUND: Fractional ablative lasers have been shown to be safe and effective for improving wrinkles, scars, skin texture, and dyspigmentation. However, the exact effects of this technology in vivo on epidermal and dermal skin constituents have not been delineated. This study evaluated the in vivo histological effects over time of treatment with a fractional ablative CO2 system, using different treatment parameters. Read More

BMJ Case Rep 2017 Oct 13;2017. Epub 2017 Oct 13.

Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

We describe a case of disfiguring facial pyoderma vegetans in order to highlight the challenges in managing this rare skin condition and review the literature.A 54-year-old woman presented to dermatology clinic with a 3-month history of a left-sided facial lesion, which had been treated as an infected sebaceous cyst. The lesion had dramatically increased in size in the weeks prior to presentation. Read More

JAMA Dermatol 2017 12;153(12):1292-1297

Department of Dermatology, Henry Ford Hospital, Detroit, Michigan.

Importance: Current models of Goltz syndrome cannot estimate the overall neocollagenesis and marked shift in collagen types after ablative fractional laser resurfacing (AFR) within treated areas of focal dermal hypoplasia (FDH).

Objectives: To clinically improve FDH by using AFR to characterize the specific ratio of collagen types associated with observed clinical changes.

Design, Setting, And Participants: This case report of a girl with Goltz syndrome used extensive laboratory evaluation and multiple observers blinded to the patient's clinical status. Read More

Clin Plast Surg 2017 Oct 21;44(4):757-766. Epub 2017 Jul 21.

Shriners Hospital for Children, 51 Blossom Street, Boston, MA 02114, USA.

In this review, the authors discuss the use of laser photothermolysis and laser resurfacing in the management of hypertrophic burn scars. They provide details regarding preoperative selection, intraoperative decision making, and postoperative care. Read More

JAMA Dermatol 2017 10;153(10):1021-1025

Department of Dermatology, University of Michigan Medical School, Ann Arbor.

Importance: Erosive pustular dermatosis (EPD) is a rare condition that typically affects actinically damaged skin of the scalp. Characterized by sterile pustules, erosions, and crusts, EPD is difficult to treat and heals slowly. The exact cause of EPD is unknown, although trauma is an inciting factor. Read More

Dermatol Surg 2017 Sep;43(9):1137-1143

*All authors are affiliated with the National Skin Centre, Singapore.

Background: Fractional carbon dioxide (CO2) laser resurfacing unites the idea of fractional photothermolysis with an ablative 10,600-nm wavelength. This technology permits effective treatment of acne scarring, with shorter recovery and a decreased side effect profile as compared to traditional CO2 laser resurfacing.

Objective: The aims of this study were to study the efficacy and safety of fractional CO2 laser for acne scars in Asian patients. Read More

J Drugs Dermatol 2017 Jul;16(7):707-710

INTRODUCTION: A topical proprietary procedural enhancement system (PES) containing a combination of active ingredients including a tripeptide and hexapeptide (TriHex Technology™, Alastin Procedure Enhancement Invasive System, ALASTIN Skincare™, Inc., Carlsbad, CA) has been used successfully to aid in healing and improve symptomatology following resurfacing procedures.

METHODS: PES (Gentle Cleanser, Regenerating Skin Nectar with TriHex Technology™, Ultra Nourishing Moisturizer with TriHex Technology™, Soothe + Protect Recovery Balm, Broad Spectrum 30+ Sunscreen) was compared to a basic regimen (Aquaphor™, Cerave™ cleanser, Vanicream™, Alastin Broad Spectrum 30+ Sunscreen) in a split face/ décolleté trial following fractional non-ablative thulium-doped resurfacing treatment to the face or décolleté. Read More

J Eur Acad Dermatol Venereol 2018 Jan 4;32(1):113-116. Epub 2017 Aug 4.

FAAD-FEADV Medical and Scientific Director, SDC The Skin Doctors Center, Trieste, Italy.

Background: Aesthetically pleasing results and fast, uneventful recovery are highly desirable after rejuvenating ablative laser procedures. Wound dressings following ablative laser procedures should ideally improve and optimize the wound healing environment.

Objective: The purpose of this comparative split-face, single-blinded, prospective observational study was to assess the efficacy and acceptability of two primary wound dressings immediately after a full-face fractional CO laser resurfacing procedure. Read More

Facial Plast Surg 2017 Jun 1;33(3):299-310. Epub 2017 Jun 1.

Meridian Plastic Surgery Center, Indianapolis, Indiana.

J Cosmet Laser Ther 2017 Aug 6;19(4):199-204. Epub 2017 Feb 6.

d Cochrane Taiwan , Taipei Medical University , Taipei , Taiwan.

Background: Laser resurfacing is used to minimize wrinkles, solar scars and sequelae of acne.

Objective: Purpose of the systematic review was to compare resurfacing outcomes of CO laser and erbium: yttrium aluminium garnet (erb:YAG) laser therapies.

Materials And Methods: Medline, Cochrane Library, EMBASE and Google Scholar databases were searched until 9 April 2015 using the following terms: laser, carbon dioxide/CO, facial wrinkles, rhytides and erbium-doped yttrium aluminium garnet/erbium:YAG/Er:YAG. Read More

J Drugs Dermatol 2016 Nov;15(11):1315-1319

Background & Objective: Surgical scars are an unwanted sequela following surgical procedures. Several different treatment modalities and approaches are currently being employed to improve the cosmesis of surgical scars with each having varying degrees of success. The objective of this study was to assess the ef cacy and safety pulsed dye laser treatment, CO2 ablative fractional resurfacing, and a combined treatment with these two modalities for the cosmetic improvement of surgical scarring that occurred following the surgical removal of skin cancer from different anatomic areas. Read More

J Am Acad Dermatol 2017 Feb;76(2):e53-e55

Department of Dermatology, Heinrich-Heine University, Düsseldorf, Germany. Electronic address:

Photomed Laser Surg 2017 May 12;35(5):278-281. Epub 2017 Jan 12.

Toyos Clinic , Nashville, Tennessee.

Fractional continuous wave CO laser resurfacing is used to improve photodamage, wrinkles, and acne scarring by surface ablation and by using heat to activate natural collagen production and dermal remodeling. In this study, the author examined the efficacy and safety of nonincisional continuous wave fractional CO laser blepharoplasty in the upper lid. Standard lid measurements including marginal reflex distance, palpebral fissure, and upper lid crease were performed preoperatively and at 6 months by the surgeon. Read More

Photomed Laser Surg 2017 Mar 30;35(3):171-175. Epub 2016 Dec 30.

4 "Laser in Dermatology, " University of Rome Tor Vergata , Rome, Italy .

Background: The CO laser has become the gold standard treatment in dermatologic surgery for the treatment of a large number of skin and mucosal lesions. The introduction of the fractional micro-ablative technology represented an integration to the ablative resurfacing technique, reducing the healing time and the side effects.

Objective: Vaginal rejuvenation performed with this technique is a minimally invasive procedure that stimulates internal tissues of the female lower genital tract to regenerate the mucosa, improving tissue trophism and restoring the correct functionality. Read More

Surgeon 2017 Dec 7;15(6):321-324. Epub 2016 Dec 7.

Department of Urology, NHS Greater Glasgow and Clyde, Glasgow, G51 4TF, Scotland, UK.

Introduction & Objective: The non-invasive nature of penile intraepithelial neoplasia (PeIN) allows for curative penile sparing therapy and is recommended, in their guidelines, by the European Association of Urology (EAU). Treatment options include topical chemotherapy, immunotherapy, laser treatment, photodynamic therapy and surgical excision. Our primary aim was to evaluate the outcome of carbon dioxide (CO) laser treatment of penile intraepithelial neoplasia. Read More

Lasers Med Sci 2017 Feb 24;32(2):283-289. Epub 2016 Nov 24.

Department of Dermatology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Ablative fractional lasers were introduced for treating facial rhytides. Few studies have compared fractional CO and Er:YAG lasers on cutaneous photodamages by a split trial. The aim of the present study was to compare these modalities in a randomized controlled double-blind split-face design with multiple sessions and larger sample size compared to previous studies done before. Read More

Lasers Med Sci 2017 Feb 24;32(2):291-295. Epub 2016 Nov 24.

Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Pran-nok Road, Bangkok, 10700, Thailand.

Topical anaesthetic cream (TAC) is commonly used as a pre-treatment of ablative fractional resurfacing (AFR) laser. Most of anaesthetic cream contains distilled water as major component. Therefore, pre-operative TAC may interfere the photothermal reaction in the skin treated with fractional carbon-dioxide (FCO) laser and fractional erbium-doped yttrium aluminium garnet (FEr:YAG) laser. Read More

J Cosmet Laser Ther 2017 Feb 2;19(1):43-48. Epub 2016 Dec 2.

b Department of Dermatology , Seoul St. Mary's Hospital , Seoul , Republic of Korea.

Background: Polydeoxyribonucleotide (PDRN) is an active compound that can promote wound healing. PDRN stimulates wound healing by enhancing angiogenesis and increasing fibroblast growth rates. Laser skin resurfacing is a popular cosmetic procedure for skin rejuvenation. Read More