Search Our Scientific Publications & Authors

Lasers Med Sci 2022 Feb 26. Epub 2022 Feb 26.

Department of Cosmetic Laser Surgery, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Xuanwu District, Jiangwangmiao Street 12, Nanjing, 210042, China.

Ablative fractional laser treatment has been extensively used for resurfacing atrophic acne scars. However, few studies have investigated how the parameters set during laser procedures affect efficacy. In this retrospective study, we examined the relationship between efficacy and Fitzpatrick skin type, gender, age, follow-up duration, energy, and treatment sessions utilizing ablative fractional carbon dioxide (CO) laser in Asians with Fitzpatrick skin types III-IV. Read More

Dermatol Surg 2022 04;48(4):441-448

Department of Dermatology, Beth Israel Deaconess Medical Center, Boston, Massachusetts.

Background: Lasers and energy-based devices (EBD) are popular treatments for skin rejuvenation and resurfacing. Achieving desired outcomes and avoiding complications require understanding the effects of these devices at a histologic level. Currently, no comprehensive review summarizing the histologic effects of laser and energy-based treatments exists. Read More

J Cosmet Laser Ther 2021 Aug 2;23(5-6):97-104. Epub 2022 Feb 2.

Physics and Laser Technology, The Higher Institute for Laser Research and Applications, Laboratroy of Medical Laser, Syria.

Fractional laser (FL) resurfacing has proved its effectiveness in acne scars treatments. To evaluate the efficacy of Fractional laser systems for treatment of acne scars as a monotherapy, and as adjunctive therapy with other treatment types. A systematic literature review was performed by searching the electronic databases PubMed, Google Scholar, and Embase. Read More

J Cosmet Dermatol 2021 Dec 21. Epub 2021 Dec 21.

Department of Dermatology, All India Institute of Medical Sciences, Bhopal, India.

Background: Fractional laser resurfacing has been used widely in management of scars. However, data for post-traumatic and post-burn scar are limited in skin of color.

Aims: This retrospective study assessed the efficacy of fractional ablative carbon dioxide laser in treatment of various types of scars other than acne scars. Read More

Aesthet Surg J 2022 Feb;42(3):239-248

Division of Ocular Imaging, Department of Ophthalmology and Visual Sciences, Paulista School of Medicine, Federal University of São Paulo (UNIFESP/ EPM), São Paulo, SP, Brazil.

Background: Periorbital fractional CO2 laser resurfacing has been employed for facial rejuvenation purposes. However, to the best of our knowledge, no study has objectively assessed periorbital neoformation and remodeling of local cutaneous collagen, in a split-face model, from skin samples obtained during upper blepharoplasty.

Objectives: The authors sought to objectively evaluate neoformation and remodeling of local cutaneous collagen after periorbital skin fractional CO2 laser resurfacing. Read More

J Dtsch Dermatol Ges 2021 11 23;19(11):1559-1568. Epub 2021 Sep 23.

Translational Research Institute, Hamad Medical Corporation, Doha, Qatar.

Recent advances in laser technology allowed the development of systems that improve texture, appearance and pliability of skin in acne scars (AS). Currently, comprehensive comparative studies on the efficacy of the most commonly used fractional systems in AS are lacking. Thus, the aim of this work was to appraise and compare the clinical response to erbium versus CO lasers in AS in the form of a meta-analysis. Read More

J Drugs Dermatol 2021 Jul;20(7):772-775

Rhinophyma is a disfiguring disorder that is characterized by an erythematous, hypertrophied, and inflamed lower two-thirds of the nose. Widely accepted as the severe form of acne rosacea, rhinophyma can result in functional, aesthetic, and psychosocial concerns that require treatment in a cosmetic fashion. Rosacea should be treated in its earliest manifestations to mitigate the progression towards rhinophyma; therefore, early detection and intervention is a crucial part of treatment. Read More

J Cutan Med Surg 2021 Nov-Dec;25(6):634-642. Epub 2021 Jul 2.

Department of Medicine, University of Toronto, ON, Canada.

Treating actinic keratosis (AK) and photodamaged skin is critical to reduce the risk of progression to skin cancer. Laser resurfacing for AK treatment is available as either lesion-directed or field therapy. Laser resurfacing removes the superficial epidermis and dermis containing actinic damage, promoting re-epithelialization of healthy skin. Read More

Skin Pharmacol Physiol 2021 26;34(5):262-270. Epub 2021 May 26.

Division of Dermatology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Background: Ablative fractional carbon dioxide laser (AFCO2) resurfacing causes transient skin barrier disruption characterized by decreased skin hydration and increased transepidermal water loss (TEWL). Snail Soothing and Repairing (SSR) cream, containing several glycoproteins with potential antimicrobial and antioxidant effects, may benefit skin hydration promotion after the laser treatment.

Objective: To evaluate the efficacy and safety of SSR cream in skin hydration promotion after AFCO2 resurfacing. Read More

Lasers Surg Med 2021 12 20;53(10):1370-1375. Epub 2021 May 20.

Istituto di Chirurgia e Laserchirurgia in Dermatologia (I.C.L.I.D.), Via della Moscova 42, Milan, 20121, Italy.

Background And Objectives: Skin photoaging is related to extrinsic environmental exposures, mainly represented by ultraviolet radiation. One of the treatment options is laser resurfacing. As nutritional status is involved in cutaneous photodamage, we evaluated whether dietary patterns can also influence the response to facial resurfacing. Read More

J Drugs Dermatol 2021 Apr;20(4):475-476

This case series demonstrates an exaggerated form of the clinical presentation of a known distressing late complication of retained hyaluronic acid filler – the “pale puffy pillow.” This presentation is often, unfortunately for the patient, misdiagnosed as festoons. However, the correction with liberal hyaluronidase is simple. Read More

Ophthalmic Plast Reconstr Surg 2021 Sep-Oct 01;37(5):450-456

Department of Ophthalmology.

Purpose: To describe postoperative management following ablative carbon dioxide laser resurfacing of the lower eyelids.

Methods: A retrospective review of patients who consecutively underwent bilateral lower eyelid ablative carbon dioxide laser resurfacing by a single experienced oculoplastic surgeon over a 6-year period was conducted. Patient satisfaction, aesthetic outcomes, and postoperative complications were evaluated as adjunctive or monotherapy. Read More

Dermatol Ther 2021 03 24;34(2):e14692. Epub 2021 Jan 24.

Plastic and Reconstructive Surgery Department, Dermatology Section, Campus Bio-Medico, University of Rome, Rome, Italy.

Among different laser types, the carbon dioxide (CO ) laser remains one of the most used by dermatologists. Its usefulness has been demonstrated both for therapeutic and cosmetic purposes. This review aims to provide an overview of the applications of CO laser in dermatology, focusing on the treatment of infective, neoplastic, and antiaesthetic lesions. Read More

J Drugs Dermatol 2020 Nov;19(11):1112-1115

Ablative fractional resurfacing (AFR) can be utilized to improve scar appearance, texture, pain and associated contractures. Non-healing ulcers can also develop in areas of scarring and, in some cases, AFR can be utilized to heal these chronic wounds. We present a case of scarring with non-healing ulceration refractory to wound care, debridement and hydrotherapy successfully healed in four sessions with AFR using a 2940 nm Er:YAG laser. Read More

J Drugs Dermatol 2020 Nov;19(11):1044-1048

Background: Laser resurfacing is the gold standard procedure for photodamage, but is not without downtime and risk. Use of periprocedural products containing stem cell conditioned media may improve results and optimize healing.

Study Design: This was a prospective, randomized controlled, double-blind study, evaluating the efficacy and tolerability of red deer umbilical cord-derived stem cell conditioned media (USCCM) cream and serum pre- and post- ablative facial resurfacing. Read More

Dermatol Ther 2021 01 2;34(1):e14432. Epub 2020 Nov 2.

Skin & Laser Surgery Center of New England, Nashua, New Hampshire, USA.

It is generally believed that ablative laser therapies result in prolonged healing and greater adverse events when compared with nonablative lasers for skin resurfacing. To evaluate the efficacy of ablative laser use for skin resurfacing and adverse events as a consequence of treatment in comparison to other modalities, a PRISMA-compliant systematic review (Systematic Review Registration Number: 204016) of twelve electronic databases was conducted for the terms "ablative laser" and "skin resurfacing" from March 2002 until July 2020. Studies included meta-analyses, randomized control trials, cohort studies, and case reports to facilitate evaluation of the data. Read More

Australas J Dermatol 2021 May 18;62(2):e286-e288. Epub 2020 Aug 18.

Duke Eye Center, Durham, NC, USA.

J Oral Maxillofac Surg 2020 Dec 13;78(12):2296.e1-2296.e7. Epub 2020 Jun 13.

Professor, Division of Oral and Maxillofacial Surgery, Departments of Surgery and Cell Biology, UT Southwestern Medical Center; and Chief, Department of Oral and Maxillofacial Surgery, Veterans Administration North Texas Healthcare System, Dallas, TX.

Rhinophyma, an unsightly and obstructive skin lesion of the nasal area, can be difficult to treat. Numerous modalities have been tried, including medical, excision, and ablation, with various tools and results. In the present report, we have demonstrated the use of the carbon dioxide (CO) laser on the nose of a 56-year-old man, with excellent cosmetic results even at 59 months after treatment. Read More

Medicine (Baltimore) 2020 Jul;99(27):e19893

Department of Plastic and Reconstructive Surgery, College of Medicine, Dongguk University, 87 Dongdae-ro, Gyeongju, Republic of Korea.

A wide range of therapeutic options are available for the treatment of Bowen disease. However, few studies have been conducted on wide excision using various resurfacing methods. The objectives of this study were:One hundred forty-eight lesions were studied. Read More

Cutis 2020 May;105(5):251-254

Maxim Healthcare Services, Sacramento, California, USA.

Aminolevulinic acid (ALA) photodynamic therapy (PDT) is a preferred method for treatment of multiple actinic keratoses (AKs) in broad skin areas (referred to as field cancerization). Pretreatment with CO2 laser ablative fractional resurfacing (AFR) may increase the efficacy of PDT. This study compared the effect and durability of CO2 laser AFR-assisted ALA-PDT vs ALA-PDT alone in the treatment of AKs and nonmelanoma skin cancers (NMSCs) at various body locations. Read More

JAMA Otolaryngol Head Neck Surg 2020 08;146(8):766-768

Daines Plastic Surgery, Skin Cancer and Reconstructive Surgery Center (SCARS Center), Newport Beach, California.

Lasers Surg Med 2021 01 11;53(1):50-54. Epub 2020 Jun 11.

Laser & Skin Surgery Center of New York, 317 East 34th Street, New York, New York, 10016.

Background And Objectives: Fractional ablative 10,600-nm carbon dioxide (CO ) laser has well-demonstrated safety and efficacy in resurfacing treatment of scars in the adult population and in the treatment of pediatric burn scars. However, there is a paucity of literature regarding laser resurfacing of traumatic and surgical scars for cosmetic benefit in the pediatric population, and in majority of cases previously reported, this was done under general anesthesia.

Study Design/materials And Methods: This was a retrospective chart review of pediatric patients under the age of 18 who underwent fractional ablative CO laser resurfacing (FALR) of traumatic or surgical scars at a single center between 2018 and 2019, inclusive. Read More

J Cosmet Dermatol 2020 Apr 20;19(4):925-929. Epub 2020 Jan 20.

Department of Dermatology, University of California, San Diego, CA.

Background: Hybrid fractional laser skin resurfacing is a procedure that combines fractional nonablative and ablative wavelengths to improve photoaging. The postoperative period involves overt skin swelling, redness, and roughness.

Objective: A single-center, randomized trial was performed to compare the effect of a standard Skincare regimen, with and without an anhydrous gel with TriHex peptides (a proprietary tripeptide and hexapeptide blend), on recovery after hybrid laser resurfacing of the face. Read More

Lasers Surg Med 2020 10 14;52(8):788-798. Epub 2020 Jan 14.

Institute of Biomedical Optics, University of Luebeck, Luebeck, 23562, Germany.

Background And Objectives: A recent generation of 5,500 nm wavelength carbon monoxide (CO) lasers could serve as a novel tool for applications in medicine and surgery. At this wavelength, the optical penetration depth is about three times higher than that of the 10,600 nm wavelength carbon dioxide (CO ) laser. As the amount of ablation and coagulation is strongly influenced by the wavelength, we anticipated that CO lasers would provide extended coagulation zones, which could be beneficial for several medical applications, such as tissue tightening effects after laser skin resurfacing. Read More

Facial Plast Surg Clin North Am 2020 Feb;28(1):17-28

Laserplast SrL StP, Piazza Eleonora Duse 2 Milano, Republic of Italy; R&D Department, Swansea Bay University Health Board and the Welsh Centre for Burns and Plastic Surgery, Moriston Hospital, Swansea SA6 6NL, United Kingdom.

Fractional CO procedures are an established, safe and effective armamentarium for managing skin rejuvenation and scarring. Very short-pulse-duration devices offer a very high ablated volume/ablated surface ratio, inducing a controlled thermal damage. With this kind of device, each procedure can be customized on the features of the skin of each patient. Read More

J Drugs Dermatol 2019 Nov;18(11):174-1176

Porokeratosis is a rare disorder of epidermal keratinization that encompasses several clinical forms, characterized by erythematous, annular plaques with an atrophic center and hyperkeratotic ridge-like border. The histopathological hallmark of porokeratosis is the cornoid lamella, a thin column of parakeratotic corneocytes embedded within the stratum corneum. There is no standard treatment regimen for porokeratosis. Read More

J Craniofac Surg 2020 Mar/Apr;31(2):e140-e144

Huseyin Guner Aesthetic Surgery Clinic, Istanbul, Turkey.

Background: More preservative approaches are being adopted in periorbital surgery each day. To avoid the possible complications of transcutaneous and transconjunctival blepharoplasty, the author has developed the safe and simple "Percutaneous Lower Blepharoplasty" technique, which he has been performing since 2008. The technique consists of the removal and transfer of lower orbital fat pads through 4-mm skin incisions with minimal dissection. Read More