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J Surg Case Rep 2020 May 23;2020(5):rjaa082. Epub 2020 May 23.

Division of Plastic Surgery, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35233, USA.

Mild- to moderate-sized lip defects that affect one- to two-thirds of the total lip length often require that utilization of local soft tissue rearrangement in order to re-establish lip anatomy, function and esthetics. The use of local flaps in lip reconstruction often follows oncologic resection of common skin malignancies including basal cell carcinoma and squamous cell carcinoma. When considering the types of flaps to use for lip defects of one- to two-third total length, a variety of flaps designs have been described, each with its benefits in drawbacks. Read More

Plast Reconstr Surg Glob Open 2020 Apr 7;8(4):e2683. Epub 2020 Apr 7.

Advanced Technologies for Regenerative Medicine and Inductive Surgery Research Center, University of Pavia, Pavia, Italy.

Background: Traditionally, nonmelanoma skin cancers (NMSCs) are considered mainly UV-related malignancies. Nevertheless, a strong correlation between the embryologically relevant sites (ERS) of the head and neck and the preferential sites of onset of basal cell carcinomas (BCCs) has long been supposed and demonstrated. The aim of this research was the investigation of the potential correlation between the ERS of the head and neck and the sites of tumor onset in all of the NMSCs. Read More

Acta Chir Plast 2020 ;61(1-4):24-27

Basal cell carcinoma (BCC) is the most prevalent malignancy, with rising incidence worldwide. Despite its naturally slow growth and initially low metastatic potential, it can cause significant morbidity and mortality when unrecognized, inadequately treated or poorly followed up. Authors present the case of a 61-year-old male with a 7-year history of multiple incomplete excisions of a “simple” BCC on the forehead. Read More

Photodiagnosis Photodyn Ther 2020 Apr 10:101761. Epub 2020 Apr 10.

Department of Dermatology, Air Force Medical Center, PLA, Beijing 100853, PR China.

Xeroderma pigmentosum (XP) is a rare autosomal recessive dermatosis that is often complicated by multiple skin tumours at exposed locations, which are difficult to treat. We report a case of a 12-year-old girl with XP treated with oral retinoic acid and photodynamic therapy (PDT) with good clinical results. She had an 8-year history of multiple skin lesions that first appeared on her nasal dorsum, but gradually increased in size and spread to her entire face, neck, and upper limbs. Read More

Medicina (Kaunas) 2020 Feb 9;56(2). Epub 2020 Feb 9.

Department of Plastic and Reconstructive Surgery, Clinical Emergency Hospital "Prof. Dr. Agrippa Ionescu", Bucharest, 011356, Romania.

: Skin cancer is one of the most frequently diagnosed malignancies. The main goal of the therapeutic management is total excision with the prevention of recurrence and metastasis. The quality of life of the patients with skin cancer is affected by the morbidity risk, surgery, and cosmetic or functional aspects. Read More

J Cutan Aesthet Surg 2019 Oct-Dec;12(4):203-211

Department of Plastic and Reconstructive Surgery, Tehran University of Medical Sciences, Imam Khomeini Hospital Complex, Tehran, Iran.

Background: Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are the most common malignancies, which occur on the scalp. There are various therapeutic methods for managing these malignancies in which the standard treatment method of both is surgical excision with a good margin. Sometimes, the patients need full-thickness excision due to the deep invasion, so exposing the underlying calvarium may be a challenge for surgeons. Read More

Klin Monbl Augenheilkd 2020 Jan 22;237(1):46-56. Epub 2020 Jan 22.

Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie, Universitätsklinikum Halle (Saale), Martin-Luther-Universität Halle-Wittenberg, Halle (Saale).

Introduction: Skin malignancies are typically localised in areas of the head that are exposed to the sun. Basal cell carcinomas (BCC) are the most frequent malignancies on the facial skin. Their incidence is raising - due to demographic changes. Read More

Eur J Surg Oncol 2020 May 27;46(5):847-854. Epub 2019 Nov 27.

Cancer Research @ UCC, Western Gateway Building, University College Cork, Ireland.

Basal cell carcinoma (BCC) are the commonest cutaneous malignancy and incidence continues to increase. There is a need to expand the therapeutic toolbox to increase options for patients that are unsuitable for or unwilling to undergo the current therapies. Electrochemotherapy (ECT) is a technique where cells are temporarily permeabilized after exposure to a brief pulsed electrical field and combined with low dose chemotherapeutics to ablate malignancies. Read More

PLoS One 2019 22;14(11):e0225511. Epub 2019 Nov 22.

Department of Pathology, Jeju National University College of medicine, Jeju, South Korea.

Basal cell carcinoma (BCC) is the most common human cancer, characterized by aberrant activation of the hedgehog (HH) signaling pathway resulting from mutations in the patched 1 (PTCH1) or smoothened (SMO) genes. In the present study, to uncover the expression profile of HH signaling-related molecules, we thoroughly examined the mRNA and protein expression levels of six molecules including GLI1, GLI2, PTCH1, PTCH2, SHH, and SMO in BCC and various other cutaneous tumors. Real-time PCR analysis demonstrated that BCC showed remarkably enhanced mRNA expression of all HH molecules, except SMO compared to other skin tumors. Read More

Rom J Morphol Embryol 2019 ;60(2):685-689

Department of Plastic Surgery and Reconstructive Microsurgery, University of Medicine and Pharmacy of Craiova, Romania;

Metatypical basal cell carcinoma (MTBCC) is a rare form of tumor, which associates the clinical and histopathological (HP) characteristics of both basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), with a 5% chance for the development of metastases. The reference diagnosis remains the HP confirmation from the lesional tissue. The current report illustrates the case of a 74-year-old patient, diagnosed with MTBCC consequently to the biopsy from the clinically malignant lesion with HP and immunohistochemical examination, currently in clinical remission following surgical treatment. Read More

Cell Physiol Biochem 2019 ;53(5):760-773

Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum, Bochum, Germany.

Background/aims: Perturbations in the expression of microRNAs (miRNAs) and their maturing machinery components such as Dicer have been previously described for basal cell carcinoma (BCC). However, the mutational status of Dicer in BCC is unclear. Further, the sclerodermiform subtype of BCC (sBCC) has not been previously investigated regarding its methylation profile or its smallRNA expression profile via RNA sequencing. Read More

Indian J Dermatol Venereol Leprol 2019 Nov-Dec;85(6):649-652

Department of Dermatology, Medical Cosmetic Center, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.

Int J Surg Case Rep 2019 11;63:23-26. Epub 2019 Sep 11.

Clinic of Plastic and Reconstructive Surgery, Department of Experimental and Clinical Medicine, Marche Polytechnic University Medical School, Via Conca 71, 60126, Ancona, Italy.

Introduction: Giant basal cell carcinomas are rare and potentially aggressive skin malignancies that are infrequently reported in the Literature, and they usually require aggressive surgical resection and immediate soft tissue reconstruction with skin grafts or flaps. The large size of GBCCs has relevant implications not only for the metastatic potential, but even for the reconstructive challenging due to the possible limited availability of tissues for flap coverage.

Presentation Of Case: We report the peculiar case of an old patient who underwent to GBCC resection of the back measuring 16 × 13 cm, and immediate reconstruction with a large O to Z flap harvested from the back; one-year follow-up examination revealed a satisfactory result and no recurrence of the disease was observed. Read More

Facial Plast Surg 2019 Aug 30;35(4):368-376. Epub 2019 Aug 30.

Department of Head and Neck Oncology and Surgery, The Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.

The European Academy of Facial Plastic Surgery celebrates its 40th anniversary. We aimed to describe innovations in the diagnostics and treatment in head and neck skin cancer over the past 40 years as well as future perspectives. Landmark events, developments, and highlights over the past decades for basal cell carcinoma, cutaneous squamous cell carcinoma, and melanoma are discussed. Read More

Br J Hosp Med (Lond) 2019 Aug;80(8):484

Consultant Plastic Surgeon, Department of Plastic Surgery, University Hospital North Midlands NHS Foundation, Trust Stoke-on-Trent.

J Craniofac Surg 2019 Nov-Dec;30(8):e748-e752

Department of Plastic Reconstructive Aesthetic Surgery, Ufuk University Faculty of Medicine, Ankara, Turkey.

We aimed to elucidate the role of intraoperative clean surgical margin (iCSM) determined according to lesion size and duration to obtain appropriate histological clean surgical margin (hCSM) in high-risk basal cell carcinoma (BCC) patients evaluated according to National Comprehensive Cancer Network (NCCN) criteria considering the tumor size and/or location. The contribution of lesion area to determine iCSM was also evaluated. Patients with high-risk BCC requiring surgical management were included. Read More

Med Arch 2019 Jun;73(3):209-212

Clinic for Ophthalmology, University Clinical Center Tuzla, Bosnia and Herzegovina.

Introduction: To the best of our knowledge, this is the first study about malignant eyelid tumors in the region of Tuzla, Bosnia and Herzegovina, and it shows similar results comparing with other countries (the annual incidence of eyelid tumors in Tuzla region is about 3.73/100 000 population). Malignant eyelid tumors are relatively uncommon, but potentially fatal disease. Read More

J Craniomaxillofac Surg 2019 Oct 16;47(10):1577-1582. Epub 2019 Jul 16.

Department of Plastic, Reconstructive and Maxillo-Facial Surgery, Henri-Mondor Hospital, AP-HP, Creteil, France.

Background: The incidence of facial skin cancers continues to rise, with major studies on their impacts still lacking in the literature. This study reports on the oncological and aesthetic results following surgical management of an orbito-palpebral skin cancer.

Methods: This retrospective, monocentric study included patients treated for a non-melanoma skin cancer of the eyelid and orbit. Read More

Photodiagnosis Photodyn Ther 2019 Dec 6;28:102-104. Epub 2019 Aug 6.

Department of Dermatology, The Affiliated Jiangning Hospital of Nanjing Medical University, No.168 Gushan Road, Dongshan Street, Jiangning District, 211100, Nanjing, Jiangsu Province, China. Electronic address:

Background: Basal cell carcinoma (BCC) that occurs in the external auditory canal (EAC) is rare. Currently reported cases are mainly treated with surgical resection. Here, we described an early-detected BCC of the EAC, which achieved good results with photodynamic therapy (PDT). Read More

J Plast Surg Hand Surg 2020 Feb 5;54(1):1-5. Epub 2019 Aug 5.

Department of Plastic and Reconstructive Surgery, Manisa Celal Bayar University, Manisa, Turkey.

Eyelid reconstruction is a challenging surgical procedure because of the special function and structure of the eyelids. There are various useful techniques which can be used to reconstruct eyelid defects. In this report, the authors aimed to present the clinical results of angular artery-based island flap for the repair of the full thickness eyelid defects. Read More

Clin Exp Otorhinolaryngol 2020 May 3;13(2):164-172. Epub 2019 Aug 3.

Department of Otorhinolaryngology, Heidelberg University Hospital, Heidelberg, Germany.

Objectives: The reconstruction after nasal skin cancer (NSC) resection is often practiced differently. The objective of this study is to evaluate the influence of patient-, tumor- and management-related factors on the role of surgery and choice of reconstruction.

Methods: This was a monocentric retrospective study of patients who were diagnosed with a NSC (squamous cell or basal cell carcinoma) and suffered from an extended defect after ablative surgery between 2003 and 2013. Read More

J Plast Reconstr Aesthet Surg 2019 Nov 27;72(11):1805-1812. Epub 2019 Jun 27.

Department of Plastic Surgery, Cambridge University Hospitals NHS Foundation Trust, UK.

Aims: Basal cell carcinoma (BCC) is the most common malignancy worldwide. Although rarely a risk to life, they are potentially destructive and disfiguring. Current treatment guidelines are predominantly based on low-risk BCC and make no recommendations regarding the deep excision margin. Read More

Clin Exp Dermatol 2020 Mar 27;45(2):165-171. Epub 2019 Aug 27.

Department of Dermatology, Venereology and Allergology, Medical University of Gdańsk, Gdańsk, Poland.

Background: The molecular pathogenesis of basal cell carcinoma (BCC) is still not precisely described and is the subject of ongoing studies. The role of signal transducers and activators of transcription (STATs) in human epithelial carcinogenesis has been poorly investigated, but in the era of studies on inhibitors targeting STAT proteins this topic seems worth exploring. Increased expression of STAT3 in human nonmelanoma skin cancer (NMSC) has been confirmed in a few studies, but to our knowledge, expression of STAT5A, STAT5B and STAT6 in BCC has not been previously evaluated. Read More

J Am Acad Dermatol 2019 Aug;81(2):581-599

Department of Dermatology and Skin Science, University of British Columbia, Vancouver, Canada.

Definitions of skin cancer recurrence are variable and nonstandardized, which can lead to inconsistent and potentially inappropriate management of tumors of uncertain recurrence status. Defining recurrence is important given the potential association with metastasis in both melanoma and nonmelanoma skin cancer. A review of the literature across multiple disciplines involved in the care of skin cancer patients reveals that although criteria for recurrence are provided in the majority of cases, most are vague and inconsistent. Read More

JAMA Ophthalmol 2019 Jul 11;137(7):e185435. Epub 2019 Jul 11.

Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts.

Horm Cancer 2019 12 28;10(4-6):145-149. Epub 2019 Jun 28.

Department of Plastic & Reconstructive and Aesthetic Surgery, Meram Faculty of Medicine, Necmettin Erbakan University, 42080, Meram, Konya, Turkey.

The study aimed to determine whether 25-OH vitamin D deficiency is present in patients with diagnosed BCC, and the effect of vitamin D replacement on the rates of BCC recurrence in patients with 25-OH vitamin D deficiency. In this prospective study, between 2012 and 2017, in the first stage, 25-OH vitamin D levels of all patients diagnosed with BCC between 2012 and 2013 were evaluated. In the second stage between 2014 and 2015, we evaluated the 25-OH vitamin D level of patients who had 25-OH vitamin D level < 25 ng/mL. Read More

Photodiagnosis Photodyn Ther 2019 Sep 21;27:291-294. Epub 2019 Jun 21.

Department of Plastic & Cosmetic Surgery, Third Military Medical University, Daping Hospital and Research Institute of Surgery, 10 Changjiang Branch Road, Daping, 400042, Chongqing, PR China. Electronic address:

Background: In recent years, photodynamic therapy (PDT) has emerged as a successful technique for treating early non-melanoma skin cancers compared with traditional methods such as surgical operation, chemotherapy, radiotherapy, and immunity treatment, etc. PDT offers excellent aesthetic results and skin function preservation effects, especially so for tumor in difficult-to-treat areas. The purpose of this article was to study the anti-tumor effect of ALA-PDT combined with limited excision in periocular basal cell carcinoma (BCC) and its role in improving the effect of the operation. Read More

Cutis 2019 May;103(5):284-287

Department of Dermatology, Texas AM University, Baylor Scott and White Health, Temple, USA.

One benefit of Mohs micrographic surgery (MMS) is maximal tissue sparing compared to standard excisional surgery techniques. It also has the highest statistical cure rate for appropriately selected nonmelanoma skin cancers (NMSCs) in cosmetically sensitive areas, making it a preferred choice for many self-referred patients or their referring physicians. Patients and nondermatologist physicians may be unaware of how frequently Mohs surgeons perform complex surgical repairs compared to other specialists. Read More

J Craniofac Surg 2019 Nov-Dec;30(8):2408-2411

Ankara Oncology Training and Research Hospital, Department of Plastic Reconstructive and Aesthetic Surgery, Ankara, Turkey.

Various local flaps have been defined for small skin defects of the nose. However, the repair of large nasal defects is only possible with flaps allowing a large tissue transfer, such as a free flap, forehead flap, and nasolabial flap. In this study, large nasal defects were reconstructed with extended central artery perforator propeller (CAPP) flaps in an attempt to describe a single-stage procedure as an alternative technique to the median forehead flap. Read More

Semin Ophthalmol 2019 9;34(4):327-333. Epub 2019 Jun 9.

a Ophthalmic Plastic Surgery , Massachusetts Eye and Ear Infirmary , Boston , MA , USA.

Immunotherapy has significantly advanced the field of oncology in recent decades. Understanding normal immunosurveillance, as well as the ways in which tumor cells have evolved to evade it, has provided the knowledge for development of drugs that allow one's own immune system to target and destroy malignant cells (immunotherapy). Cutaneous malignancies are particularly sensitive to this class of drugs. Read More

Am J Dermatopathol 2019 Oct;41(10):744-746

Department of Dermatology, Hospital General Universitario de Valencia, Valencia, Spain.

The differential diagnosis of Grover disease (GD) includes pemphigus foliaceus. However, the focal nature of the histologic findings and negative direct immunofluorescent point to the diagnosis of GD. It has been associated with a variety of systemic and cutaneous diseases, but its association with other primary acantholytic disorders has been rarely documented. Read More

Indian J Dermatol Venereol Leprol 2019 Sep-Oct;85(5):475-480

Department of Dermatology and Venereology, Faculty of Medicine, Tanta University, Tanta, Egypt.

Background: Basal cell carcinoma is the most common form of skin cancer worldwide. It has a specialized microvasculature system that can be targeted by the pulsed dye laser using the theory of selective photothermolysis.

Objective: To evaluate the efficacy and safety of single session versus two sessions of pulsed dye laser in the treatment of basal cell carcinoma. Read More

Curr Oncol 2019 04 1;26(2):114-118. Epub 2019 Apr 1.

Saskatchewan Cancer Agency, Saskatoon, SK.

Introduction: Given the high occurrence and morbidity of non-melanoma skin cancer (nmsc), its economic burden on the Canadian health care system is a cause for concern. Despite that relevance, few studies have used patient-level data to calculate the cost of nmsc. The objective of the present study was to use physician billing data to describe the health care costs and service utilization associated with nmsc in Saskatchewan. Read More

Australas J Dermatol 2019 Nov 22;60(4):294-300. Epub 2019 Apr 22.

Department of Population Health, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

Background/objective: To describe the clinical settings in which keratinocyte cancers are excised in Queensland and describe the types of practitioners who excise them; to examine costs; and to identify predictors of hospital admission.

Methods: We used linked data for participants from the QSkin study (n = 43 794), including Medicare claims and Queensland hospital admissions relating to treatment episodes for incident keratinocyte cancers from July 2011 to June 2015. We used multinomial logistic regression to measure associations between demographic and clinical characteristics and treatment setting. Read More

J Clin Med 2019 Apr 3;8(4). Epub 2019 Apr 3.

Department of Dermatology, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.

Current national and European guidelines recommend distinct management approaches for basal cell carcinoma (BCC) based on tumor location, size, and histopathological subtype. In vivo reflectance confocal microscopy (RCM) is a non-invasive skin imaging technique which may change the diagnostic pathway for BCC patients. This study aimed to determine the sensitivity and specificity of RCM for BCC diagnosis, assess the predictive values of several confocal criteria in correctly classifying BCC subtypes, and evaluate the intraobserver reliability of RCM diagnosis for BCC. Read More

Acta Biomed 2019 01 22;90(1):77-82. Epub 2019 Jan 22.

Department of Medicine and Surgery, Plastic Surgery Division, University of Parma, Parma, Italy; Cutaneous, Mini-invasive, Regenerative and Plastic Surgery Unit, Parma University Hospital, Parma, Italy..

Aim: Basal Cell Carcinoma (BCC) alone accounts for 80% of cases of non-melanoma skin cancer (NMSC), which characteristically develops on sun-exposed skin. Indeed the most common site of BCC is the head and neck region (80%). The purpose of this study to review the experience of our center with BCC in the head and neck region to report the sites of occurrence and treatment. Read More

Ann Plast Surg 2019 05;82(5):533-536

Department of Plastic, Reconstructive and Aesthetic Surgery, University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.

Background: Helical rim reconstruction is relatively difficult because of the unique anatomical structure of the ear. The aesthetic and functional characteristics of the ear make such reconstruction even more important. This article presents the newly defined chondrocutaneous hatchet flap-Z plasty (HFZP) method in helical rim defects and evaluates the results. Read More

Surv Ophthalmol 2019 Sep - Oct;64(5):659-667. Epub 2019 Mar 11.

Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA; Ophthalmic Plastic Surgery Service, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA. Electronic address:

Merkel cell carcinoma (MCC) is a rare, aggressive tumor of both epithelial and neuroendocrine origin, which carries a mortality rate of up to 40%. MCC tumors typically present as painless, expanding nodules on the sun-exposed skin areas of older, white patients. Eyelid and periocular tumors comprise approximately 2. Read More

Am J Otolaryngol 2019 May - Jun;40(3):445-447. Epub 2019 Feb 19.

Otolaryngology and Facial Plastic Surgery Associates, Fort Worth, TX, United States of America.

The nose is a complex structure important for aesthetic appearance, social interaction, and respiration. Full thickness nasal defects with resection of the septum pose a significant challenge to the reconstructive surgeon due to the lack of local tissues to replace the nasal lining and significant risk of nasal collapse owing to the paucity of rigid infrastructure. The purpose of this paper is to present a unique case of nasal reconstruction utilizing a bilaminar paramedian forehead flap (combined pericranial flap and forehead flap) with embedded cantilever rib graft in a patient who underwent resection for an intranasal malignancy involving the septum and soft tissue envelope. Read More

BMJ Open 2019 02 22;8(11):e023299. Epub 2019 Feb 22.

Plastic Surgery Department, Salisbury District Hospital, Salisbury, UK.

Objectives: To assess compliance with 2010 National Institute for Health and Care Excellence (NICE) guidance on cancer services relating to the management of basal cell carcinomas (BCC) in the community, where except in specific circumstances it is recommended that only low-risk BCCs should be excised routinely.

Design And Setting: A retrospective observational study of the histopathology reports of BCC excisions received from primary care in two district general hospitals in the South of England. One hundred consecutive BCC excisions were analysed from each hospital. Read More

J Dtsch Dermatol Ges 2019 Feb;17(2):214-230

Department of Dermatology, Mainz University Medical Center, Mainz, Germany.

Basal cell carcinoma (BCC) is the most common malignant tumor among fair-skinned individuals, and its incidence had been steadily rising in the past decades. In order to maintain the highest quality of patient care possible, the German S2k guidelines were updated following a systematic literature search and with the participation of all professional societies and associations involved in the management of the disease. Part 2 addresses issues such as proper risk stratification, the various therapeutic approaches, and prevention as well as follow-up of patients with basal cell carcinoma. Read More

J Surg Oncol 2019 Jun 8;119(7):903-908. Epub 2019 Feb 8.

Department of Plastic Surgery and Hand Surgery, Medical Centre Leeuwarden, Leeuwarden, The Netherlands.

Background And Objectives: Recent studies show that whole specimen intraoperative frozen section analysis (WIFSA) is a reliable method for margin analysis in basal cell carcinoma (BCC) and has low recurrence rates after five-years follow-up. There are no studies with longer follow-up. Our aim is to present long-term recurrence rates after WIFSA. Read More

J Surg Oncol 2019 Jun 4;119(7):974-978. Epub 2019 Feb 4.

Department of Plastic Surgery, Changhai Hospital, Second Military Medical University, Shanghai, China.

Objective: We aimed to explore the efficacy of keystone flap combined with vacuum-assisted closure (VAC) in the repair of sacrococcygeal wounds.

Methods: This study is a retrospective review of patients undergoing keystone flap reconstruction between January 2014 and January 2018. A standardized data collection template was used to collect related variables. Read More

J Plast Reconstr Aesthet Surg 2019 May 9;72(5):848-862. Epub 2019 Jan 9.

Department of Plastic and Reconstruction, Shanghai Changhai Hospital Affiliated to Second Military Medical University, Shanghai, People's Republic of China. Electronic address:

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2019 01;33(1):66-69

Department of Burn Plastic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi Guizhou, 563003, P.R.China.

Objective: To investigate the effectiveness of relay flap on repairing skin and soft tissue defect of auricle and donor site.

Methods: Between May 2014 and January 2016, 10 patients with auricular tumor were repaired by relay flap. There were 4 males and 6 females with an average age of 35 years (range, 21-69 years). Read More

Biomed Res Int 2018 16;2018:4678362. Epub 2018 Dec 16.

Assistant Professor, Department of Dermatology and Venereology, Holy Family Red Crescent Medical College and Hospital, Dhaka, Bangladesh.

Bangladesh is grappling with the largest mass poisoning of a population in the world due to contamination of drinking water with naturally occurring inorganic arsenic. It is estimated that 75 million people of 59 (out of 64) districts are at risk of drinking contaminated water with arsenic above 50g/L. Long term exposure to arsenic causes cancers, including skin, lung, and bladder. Read More

J Craniofac Surg 2019 Mar/Apr;30(2):412-417

Division of Plastic and Reconstructive Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.

Background: Defects following Mohs micrographic surgery (MMS) can range in size from small defects requiring linear closure to large defects needing flap coverage. Reconstruction is dependent on defect size and facial aesthetic unit involvement. The aim of this study was to review the types of facial reconstruction per aesthetic unit involvement and describe their outcomes. Read More

Pan Afr Med J 2018 30;30:300. Epub 2018 Aug 30.

Service de Dermatologie-Vénérologie, Hôpital d'Instruction Mohammed V, Rabat, Maroc.

Basal cell carcinoma (BCC) is the most frequent skin cancer. It never affects the mucosa. It is characterized by a local malignancy with an extremely rare risk of developing distant metastasis and the lowest mortality. Read More

J Dtsch Dermatol Ges 2019 Jan 28;17(1):94-103. Epub 2018 Dec 28.

Department of Dermatology, Mainz University Medical Center, Mainz, Germany.

Basal cell carcinoma is the most common malignant tumor among fair-skinned individuals, and its incidence has been rising steadily in the past decades. In order to maintain the highest quality of patient care possible, the German S2k guidelines were updated following a systematic literature search and with the participation of all professional societies and associations involved in the management of the disease. Part 1 highlights new developments in genetics in particular as well as aspects regarding epidemiology, diagnosis, and histology. Read More

J Cutan Med Surg 2019 May/Jun;23(3):258-264. Epub 2018 Dec 17.

2 Department of Plastic Reconstructive and Aesthetic Surgery, Marmara University School of Medicine, Istanbul, Turkey.

Background: The most common skin cancer is basal cell carcinoma (BCC), and the gold-standard treatment for high-risk tumours is Mohs surgery. However, alternative methods are needed for high-risk tumours in countries where the performance rate of Mohs surgery is low.

Objectives: The objective of this article is to investigate the feasibility, efficacy, and safety of margin-controlled, staged surgical excision (MCSSE) in high-risk tumours as a possible treatment alternative. Read More