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JNMA J Nepal Med Assoc 2022 Mar 11;60(247):314-317. Epub 2022 Mar 11.

Patan Academy of Health Sciences, Lagankhel, Lalitpur, Nepal.

Diaphragmatic eventration is a rare condition, and its association with dextrocardia is even a rarer clinical entity. Patients are usually asymptomatic, but the typical features include rapid breathing and recurrent respiratory infections. Here we present a rare case of a seven months old infant, who presented with cough, noisy breathing and chest retraction. Read More

Diagnostics (Basel) 2022 May 19;12(5). Epub 2022 May 19.

Department of Surgery, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Background: Laparoscopic cholecystectomy in situs inversus totalis (SIT) is a technically and physically demanding procedure for surgeons and there is still a lack of consensus regarding the best technical approach in such cases. We conducted a systematic review and meta-analysis to evaluate port placement, the dominant hand of the surgeon, preoperative imaging, morbidity, and mortality.

Methods: We searched MEDLINE, SCOPUS, Web of Science, and the Cochrane Library for studies of patients with SIT that underwent laparoscopic cholecystectomy. Read More

BMJ Case Rep 2022 04 15;15(4). Epub 2022 Apr 15.

Radiodiagnosis, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, India.

Cureus 2022 Mar 8;14(3):e22947. Epub 2022 Mar 8.

Anaesthesia, Rajmata Vijaya Raje Scindia Medical College, Bhilwara, IND.

Left-sided acute appendicitis (LSAA) is a rare cause of acute pain in the abdomen and is associated with developmental anomalies such as situs inversus (viscus) totalis (SIT) and midgut malrotation (MM). Due to the rarity along with the atypical presentation, diagnosis of LSAA is difficult, and if it is not managed timely, complications of appendicitis such as perforation can result. Imaging including contrast-enhanced CT scans and ultrasound aids in establishing the diagnosis. Read More

Acta Otorrinolaringol Esp (Engl Ed) 2022 Mar-Apr;73(2):133-134

Hospital Universitario Virgen de la Victoria, Campus de Teatinos, Málaga, Spain.

Pediatr Surg Int 2022 Jun 7;38(6):875-881. Epub 2022 Apr 7.

Department of Pediatric Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.

Purpose: Though gastric volvulus in neonates and infants resolves by conservative therapy and aging, some cases require surgical intervention. This study aimed to review the cases of gastric volvulus requiring surgical intervention and evaluate their characteristics.

Methods: We retrospectively reviewed gastric volvulus cases requiring surgical intervention. Read More

Front Med (Lausanne) 2022 9;9:840795. Epub 2022 Mar 9.

Department of Nuclear Medicine and Institute of Anesthesiology and Pain, Taihe Hospital, University of Medicine, Shiyan, China.

A 62-year-old female patient with pathologically confirmed left lung small cell neuroendocrine carcinoma. The patient was referred to our positron emission tomography (PET)/CT center to look for possible metastatic diseases. After fasting for 8 h, the fasting blood glucose level of the patient was 7. Read More

J Int Med Res 2022 Mar;50(3):3000605221088551

The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou 510080, Guangdong Province, China.

Dextrocardia is a congenital abnormal position of the heart in which the main part of the heart is in the right chest, and the long axis of the heart points to the lower right. Cases of a combination of dextrocardia and sick sinus syndrome are rare. A 65-year-old female patient was admitted to hospital with palpitations and dizziness for 1 week. Read More

J Card Surg 2022 Jun 17;37(6):1574-1584. Epub 2022 Mar 17.

Department of Cardiovascular Radiology & Endovascular Interventions, All India Institute of Medical Sciences, New Delhi, India.

Aim: To study the imaging characteristics and the associations of left atrioventricular valve atresia with patent aortic root and lateralized atrial chambers on multidetector computed tomography (CT) angiography.

Materials And Methods: We retrospectively evaluated all the CT angiography studies performed for the evaluation of various congenital heart diseases at our center from January 2014 to December 2021. Cases with left atrioventricular valve atresia and patent aortic root with lateralized atrial chambers were identified. Read More

BMC Med Genomics 2022 03 12;15(1):55. Epub 2022 Mar 12.

Department of Ultrasonography, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430070, China.

Background: Short-rib thoracic dysplasia 3 with or without polydactyly (SRTD3, OMIM: 613091) is an autosomal recessive disorder. SRTD3 presents clinically with a narrow thorax, short ribs, shortened tubular bones, and acetabular roof abnormalities. Clinical signs of SRTD3 vary among individuals. Read More

Int J Gen Med 2022 3;15:2437-2449. Epub 2022 Mar 3.

Department of Surgery, Transplantation and Gastroenterology, Semmelweis University, Budapest, Hungary.

Situs inversus totalis is a rare congenital abnormality characterized by a mirror-image transposition of both the abdominal and the thoracic organs. While this anomaly is known since the ancient times, practicing doctors do not have much experience with it. Laterality is established early in development, and any failure in that process might lead to a wide variety of disorders which may be partial or complete. Read More

Kyobu Geka 2022 Feb;75(2):88-91

Department of Cardiovascular Surgery, Omi Medical Center, Kusatsu, Japan.

Situs inversus totalis is a congenital anomaly characterized by a mirror image transposition of the normal visceral organs, which makes it difficult to perform aortic surgery accurately. Stanford type A aortic dissection in patients with this condition is very rare and difficult to assess and manage. We report a case of Stanford type A aortic dissection with situs inversus totalis. Read More

BMJ Case Rep 2022 Feb 28;15(2). Epub 2022 Feb 28.

Department of Cardiology, Shobara Red Cross Hospital, Shobara, Hiroshima, Japan

An 85-year-old woman presenting with symptomatic pulmonary hypertension (PH) with a history of dextrocardia was referred to our facility for treatment of heart failure. Significant shunting was detected by measuring oxygen saturation during right heart catheterisation (RHC). CT with contrast revealed sinus venosus atrial septal defect (SVASD) and partial anomalous pulmonary venous connection (PAPVC), in which the left upper and middle lobar pulmonary veins returned to the superior vena cava and right atrium. Read More

World J Clin Cases 2022 Feb;10(4):1333-1340

Department of Emergency Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, Guizhou Province, China.

Background: Single atrium with single ventricle, or a two-chambered heart, is an extremely rare congenital malformation. Few cases with two-chambered heart surviving to adulthood have been reported.

Case Summary: We reported an adult female patient with a two-chambered heart and situs inversus totalis accompanied by multiple pregnancies and abortions. Read More

JNMA J Nepal Med Assoc 2022 Feb 15;60(246):196-199. Epub 2022 Feb 15.

Department of Surgery, Capital Hospital Pvt. Ltd., Kathmandu, Nepal.

Dextrocardia is an unusual inherent positioning of the heart: during fetal life, the heart is flipped to the right side rather than the usual left side. Situs inversus is a rare congenital ailment in which the main internal organs are rearranged or reflected from their natural positions, and when both conditions are present, it is called situs inversus totalis. The majority of the people with situs inversus totalis are unaware of the situation they have because most of them are asymptomatic. Read More

BMC Gastroenterol 2022 Feb 10;22(1):56. Epub 2022 Feb 10.

BreathMAT Lab, Pakistan Institute of Nuclear Science and Technology, Islamabad, Pakistan.

Background: Type 2 isolated dextrogastria in conjunction with protrusion of the right hemidiaphragm and hiatal hernia is an uncommon anomaly among all transpositions of the viscera. Clear diagnosis is not straightforward in such cases both clinically and with various imaging techniques leaving often only laparotomy for diagnosis.

Case Presentation: Here, we discuss the case of a so far asymptomatic 19-year-old male, who had a 3-month history of abdominal pain and 2 days of vomiting with absolute constipation, and reduced air entry in the base of the right lung. Read More

J Formos Med Assoc 2022 Feb 5. Epub 2022 Feb 5.

Departments of Pediatrics, National Taiwan University Hospital, Medical College, National Taiwan University, Taiwan.

Background/purpose: Inferior vena cava (IVC) interruption is rare and can be detected through prenatal or postnatal imaging. It usually occurs in patients with heterotaxy syndrome with bilateral left-sidedness (left isomerism or polysplenia syndrome), indicating a laterality defect. However, its long-term outcomes remain unclear. Read More

Pediatr Pulmonol 2022 05 21;57(5):1318-1324. Epub 2022 Feb 21.

Respiratory Medicine, McGill University Health Centre Research Institute, Quebec, Montreal, Canada.

Background: Organ laterality defects in primary ciliary dyskinesia (PCD) are common, ranging from complete mirror image organ arrangement, situs inversus totalis (SIT), to situs ambiguus (SA), which falls along the spectrum of situs solitus (SS) and SIT. Targeted investigations for organ laterality defects are not universally recommended in PCD consensus statements. Without investigations beyond chest radiography (CXR), clinically significant defects may go undetected leading to increased morbidity. Read More

BMC Cardiovasc Disord 2022 01 29;22(1):20. Epub 2022 Jan 29.

Department of Cardiology, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.

Background: Dextrocardia is a rare congenital condition (1/10,000-12,000) and AF is uncommon (1-2%). Therefore, the occurrence of the two conditions is rare. Percutaneous left atrial appendage occlusion (LAAO) is a treatment to prevent atrial fibrillation (AF)-associated thromboembolic events. Read More

J Emerg Med 2022 03 20;62(3):e77-e79. Epub 2022 Jan 20.

Department of Emergency Medicine, Cleveland Clinic Akron General, Akron, Ohio; Northeast Ohio Medical University, Rootstown, Ohio.

J Gastroenterol 2022 02 22;57(2):111-119. Epub 2022 Jan 22.

Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.

Background: Hepatocellular carcinoma (HCC) is a long-term complication of Fontan-associated liver disease (FALD). However, risk factors for HCC in patients with FALD remain unclear. This study aimed to identify factors associated with HCC development post-Fontan procedure. Read More

BJR Case Rep 2021 Jul 4;7(4):20200202. Epub 2021 Mar 4.

Southend University Hospital, Mid and South Essex NHS Foundation trust, Southend-on-Sea, UK.

Situs inversus is an uncommon condition in which there is transposition of thoracic and abdominal structures. We report a case of situs inversus totalis detected incidentally in a 72-year-old female under investigation for haematuria. The imaging findings and role of imaging in this condition have been described in detail. Read More

Pacing Clin Electrophysiol 2022 Mar 7;45(3):340-347. Epub 2022 Feb 7.

Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Background: Patients with tachycardia, in the context of pre-existing dextrocardia, could benefit from catheter ablation. However, anatomical complexities hinder effective conduct of this procedure. We aimed to retrospectively summarize the clinical characteristics and the safety and efficiency, and recommended the technique considerations. Read More

Int J Surg Case Rep 2022 Feb 12;91:106767. Epub 2022 Jan 12.

Department of Pathology, Tobata Kyoritsu Hospital, 2-5-1 Sawami, Tobata-ku, Kitakyushu City, Fukuoka Prefecture 804-0093, Japan.

Introduction: Situs inversus totalis represents an unusual anomaly characterized by a mirror-image transposition of the abdominal and thoracic viscera. It often occurs concomitantly with other disorders, hindering the diagnosis and management of abdominal pathology. The relationship between situs inversus totalis and cancer remains unclear. Read More

J Cardiol Cases 2022 Jan 9;25(1):26-29. Epub 2021 Jul 9.

Cardiology Hospital, Policlinico of Bari, Bari, Italy.

Inadvertent placement of pacemaker and implantable cardioverter-defibrillator (ICD) leads in the left ventricle is a rare but well-recognized complication of device implantation. We report a case of an unicameral ICD lead inadvertently placed through the left subclavian artery right positioned, across the aortic valve into the left ventricle, in a patient with situs viscerum inversus. A transthoracic echocardiogram about a month after the procedure showed an unusual course of the lead. Read More

J Int Med Res 2022 Jan;50(1):3000605211072785

Department of Neurology, Heyuan People's Hospital, Guangdong Provincial People's Hospital Heyuan Hospital, Guangdong Province, China.

Cases of patients complicated with dextrocardia who suffer from acute cerebral infarction with large vessel occlusion and receive emergency thrombectomy are particularly rare and have not been widely reported. This article aimed to increase the awareness and knowledge of these cases. We report the case of a patient with mirror-image dextrocardia who suffered from cerebral infarction with large vessel occlusion and received emergency thrombectomy. Read More

Radiol Case Rep 2022 Mar 28;17(3):735-739. Epub 2021 Dec 28.

Thoracic Radiologist, Department of Radiology, Faculty of Medicine Universitas Airlangga - Dr. Soetomo Academic General Hospital, Surabaya, Indonesia.

Situs inversus with a coronary artery defect is an extremely rare congenital anomaly, which is often only incidentally detected during cardiac imaging studies, particularly when the patient is complaining of chest pain. We present a case study of a 37-year-old man who presented with a 3-month history of chest pain. A chest X-ray revealed dextrocardia with stomach gas in the lower right diaphragm. Read More

Radiol Case Rep 2022 Mar 22;17(3):650-655. Epub 2021 Dec 22.

Department of Surgery, Mayo Clinic, 200 1st St SW, Rochester, MN 55905.

Situs inversus totalis (SIT) is a rare developmental abnormality where the organs throughout both the thoracic cavity and abdomen are a mirror image of normal anatomy, often occurring concomitantly with other genetic and developmental defects. Acute spinal cord ischemia is diagnosed based on the clinical presentation along with consistent imaging, but since clinical manifestations of acute spinal cord ischemia- rapidly progressive motor, sensory, and autonomic dysfunction-overlap with a wide spectrum of myelopathies, a thorough diagnostic workup with consideration of inflammatory, infectious, compressive and nutritional etiologies is required to establish the diagnosis. In this report, we present the case of an 18-year-old female patient who was admitted with acute onset of severe lower back pain, progressive weakness, paralysis, loss of sensation in both lower limbs and voiding difficulties. Read More

Asian J Surg 2022 Mar 6;45(3):978-979. Epub 2022 Jan 6.

The Second Department of General Surgery, Gansu Provincial Hospital, Lanzhou, 730000, China; Lanzhou University People's Clinical Hospital, Lanzhou, 730000, China; Gansu Research Center of Prevention and Control Project for Digestive Oncology, Gansu Provincial Hospital, Lanzhou, 730000, China; Gansu key Laboratory of Molecular Diagnostics and Precision Medicine for Surgical Oncology, Gansu Provincial Hospital, Lanzhou, 730000, China. Electronic address:

Clin Radiol 2022 04 31;77(4):e261-e268. Epub 2021 Dec 31.

University Hospital Birmingham NHS Trust, Birmingham, UK.

Transposition of the great arteries is one of the most common cyanotic congenital heart diseases. It is characterised by an abnormal connection of the ventricles and great arteries, so that the aorta arises from the morphological right ventricle and the pulmonary artery arises from the morphological left ventricle. Historically, as with many congenital heart diseases, patients with transposition of the great arteries had poor life expectancy. Read More