5,987 results match your criteria Sinusitis Fungal

Characterization of fungus ball CT-hyperdensities within maxillary and sphenoid sinuses.

Dentomaxillofac Radiol 2022 Jun 28:20180384. Epub 2022 Jun 28.

Department of Otorhinolaryngology-Head and Neck Surgery, University Hospital of Bordeaux, Bordeaux, France.

Objectives: CT-Scan hyperdensities are described in more than 60% of all paranasal sinus fungus ball cases. Two types can be distinguished according to their density: calcium and metal types. We aimed to establish the prevalence and density of the hyperdensities observed in sphenoid and maxillary sinus fungus ball and their relation to dental factors. Read More

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-Cause of Nonspecific Acute Sinusitis: First Case Report and Review of Literature.

Microorganisms 2022 Jun 9;10(6). Epub 2022 Jun 9.

Department of Clinical Microbiology, Clinical Hospital Center Rijeka, Krešimirova 42, 51000 Rijeka, Croatia.

Although most sinus infections are viral, potential bacterial pathogens such as , and can migrate during a viral respiratory infection from the nasopharynx into the sinus cavity causing sinusitis. is a commensal of the external auditory canal and is considered one of the potential middle ear pathogens. Unlike most otopathogens, is rarely found in the nasopharynx of healthy individuals. Read More

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May   Be an Etiological Factor of Chronic Maxillary Sinuses Infection?

Int J Mol Sci 2022 Jun 9;23(12). Epub 2022 Jun 9.

MML Centre, Bagno 2, 00-112 Warsaw, Poland.

  is an opportunistic pathogen found in the healthy human skin microbiome bacterial community that is able to cause infections of diverse localization, manifestation, and course, including laryngological infections, such as necrotizing sinusitis. Chronic maxillary sinusitis is a disease present in up to one third of European and American populations, and its etiology is not fully described. Within this study, we aimed to characterize 18 strains recovered from maxillary sinuses and evaluate them as etiological agents of chronic disease. Read More

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Solitary Sphenoid Sinus Lesion Presenting as Chronic Headache.

J Craniofac Surg 2022 May;33(3):886-888

Department of Otolaryngology-Head and Neck Surgery, Kosin University College of Medicine, Busan, South Korea.

Background And Objectives: Headache is a common symptom with etiologies that are difficult to distinguish, 1 of which is sinusitis. A solitary sphenoid lesion, which is rare, can also cause acute or chronic headaches. The authors investigated whether endoscopic sinus surgery (ESS) for solitary sphenoid lesions could reduce headache symptoms. Read More

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Isolated Fungal Sphenoid Sinusitis With Cavernous Sinus Thrombophlebitis: A Case Report.

Cureus 2022 May 16;14(5):e25034. Epub 2022 May 16.

Clinical Neurosciences, University of the East Ramon Magsaysay Memorial Medical Center, Quezon City, PHL.

Cavernous sinus thrombophlebitis is a rare, potentially life-threatening, condition that is most often caused by gram-negative bacteria and, to a lesser extent, fungi. is an opportunistic fungus that frequently affects patients with a weak immune system. We describe a case of an adult female without diabetes who developed sphenoid sinusitis causing cavernous sinus thrombophlebitis. Read More

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[Clinical observation of 8 cases with central nervous system anaerobic infection diagnosed by metagenomic next-generation sequencing of cerebrospinal fluid].

Zhonghua Yi Xue Za Zhi 2022 May;102(20):1533-1536

Department of Neurology, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, China.

The current study summarized the clinical characteristics of 8 patients with central nervous system anaerobic infections who visited the Second Hospital of Hebei Medical University from June 2019 to June 2021. Among the 8 patients, 7 cases had headache and fever as the first symptoms, and 1 case had left-sided limb weakness as the first symptom. Four patients had a previous history of diabetes (1 patient had a history of tooth extraction before the onset of the disease), 1 patient had a previous history of sinusitis, 1 patient had a history of tooth extraction before the onset of the disease, and 2 patients had chronic extensive periodontitis or periapical periodontitis. Read More

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Specific antibody deficiency: Pearls and pitfalls for diagnosis.

Ann Allergy Asthma Immunol 2022 Jun 4. Epub 2022 Jun 4.

Department of Medicine - University of Virginia, Charlottesville, Virginia; Department of Microbiology - University of Virginia, Charlottesville, Virginia.

Objective: Specific antibody deficiency is an immune deficiency defined by the presence of normal quantitative levels of immunoglobulins but impaired antibody responses to polysaccharide antigens in patients presenting with frequent otosinopulmonary infections with pyogenic bacteria. This review summarizes the pitfalls associated with defining exactly what constitutes an "impaired" antibody response to polysaccharide antigens and the importance of documenting actual pyogenic infections before making a diagnosis of an immune deficiency.

Data Sources: PubMed review using the following words: specific antibody deficiency, pneumococcal vaccination, salmonella vaccination, infectious sinusitis Study Selection: This review focused on key studies that have been utilized to define what constitutes a "normal" humoral immune response to pneumococcal and salmonella vaccination in healthy subjects as well as published papers defining current expert opinion. Read More

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Viral cytopathic effect in maxillary sinus epithelium and SARS-CoV-2: Pitfalls in diagnostic characterization.

J Oral Biol Craniofac Res 2022 Jul-Aug;12(4):437-438. Epub 2022 May 25.

Department of Oral Pathology and Microbiology, Dr. D.Y. Patil Dental College and Hospital, Dr. D.Y. Patil Vidyapeeth, Sant-Tukaram Nagar, Pimpri, Pune, 411018, MH, India.

Viral cytopathic effects (VCE) are a well-known phenomenon associated with SARS-CoV-2 infection, especially in the cells associated with the lungs. Because maxillary sinus epithelium expresses angiotensin-converting enzyme 2, cells associated with it are more likely to become infected with SARS-CoV-2 and develop VCE. If VCE is seen in with background of a confirmatory COVID-19 diagnosis, then connecting both become quite convincing. Read More

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Series of isolated sphenoid disease: Often neglected but perilous.

SAGE Open Med Case Rep 2022 19;10:2050313X221097757. Epub 2022 May 19.

Department of Otorhinolaryngology, Hospital Sultanah Bahiyah, Alor Setar, Malaysia.

Isolated sphenoid sinus disease (ISSD) is an uncommon entity and may present with non-specific symptoms. As sphenoid sinus is located adjacent to vital structures, a diseased sphenoid sinus can potentially lead to devastating complications such as cranial neuropathies, cavernous sinus thrombosis and intracranial abscess. Herein, we report a case series of three patients who presented with different localization of headache as their main symptom. Read More

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Disseminated fusariosis with cerebral involvement in a patient with acute myeloid leukemia: Successful outcome with intrathecal -and systemic antifungal treatment.

J Infect Chemother 2022 May 28. Epub 2022 May 28.

Department of Infectious Medicine, Rigshospitalet, Copenhagen, Denmark.

The outcome of invasive fusariosis in hematological patients is usually dismal, particularly in patients with persistent neutropenia. We report a patient with acute myeloid leukemia (AML) with Fusarium dimerum sinusitis with hematogenic dissemination to the brain. Despite surgical debridements of the sinuses and liposomal amphotericin B, voriconazole and terbinafine, there was progression with cerebral involvement after recovery of neutropenia and with detection of F. Read More

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IRVAN syndrome: A case report and a literature review.

Ann Med Surg (Lond) 2022 May 4;77:103725. Epub 2022 May 4.

Department of Ophthalmology, Zaid Al Sharity National Hospital, As'suwayda, Syrian Arab Republic.

Introduction And Importance: Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome is a rare retinal defect. It has a female predominance. The staging of IRVAN was defined depending on ocular criteria. Read More

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Foreign Bodies in Sinonasal Tissues: A Potential Pitfall yet a Hint to Oroantral Fistulas.

Int J Surg Pathol 2022 May 29:10668969221101863. Epub 2022 May 29.

Oral and Dental Surgery Unit, 62743Rashid Hospital, Dubai, United Arab Emirates.

Foreign bodies in the maxillary sinus are infrequent findings with various organic and inorganic materials have been reported. Most are iatrogenic due to abnormal communications between the oral cavity and the sinus cavity, predominantly secondary to dental and oral procedures. Oroantral fistulas might be asymptomatic incidental findings or may present with sinusitis-related symptoms. Read More

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Invasive Rhinosinusitis Caused by in a Patient with Autosomal Recessive CARD9 Deficiency and a Review of the Literature.

J Fungi (Basel) 2022 Apr 25;8(5). Epub 2022 Apr 25.

Université de Paris, Necker-Pasteur Center for Infectious Diseases and Tropical Medicine, Necker-Enfants Malades University Hospital, Assistance Publique des Hôpitaux de Paris (AP-HP), 75015 Paris, France.

Phaeohyphomycoses comprise a heterogeneous group of fungal infections caused by dematiaceous fungi and have primarily been reported in patients with underlying acquired immunodeficiencies, such as hematological malignancies or solid-organ transplants. Over the past decade, a growing number of patients with phaeohyphomycosis but otherwise healthy were reported with autosomal recessive (AR) CARD9 deficiency. We report a 28-year-old woman who presented with invasive rhinosinusitis caused by . Read More

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Invasive fungal infection caused by species in a patient with intranasal drug use: A case report.

Med Mycol Case Rep 2022 Sep 14;37:1-3. Epub 2022 May 14.

Department of Internal Medicine, Eastern Virginia Medical School, Norfolk, VA, USA.

Chronic invasive fungal sinusitis (CIFS) is an invasive fungal infection that can occur in immunocompetent individuals and is typically caused by species. Although many reported cases are unable to identify an etiology for the infection, certain risk factors such as chronic intranasal cocaine use can make patients susceptible to CIFS. This case report describes a unique case of CIFS secondary to species in an immunocompetent patient with intranasal drug use. Read More

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September 2022

Odontogenic sinusitis: A state-of-the-art review.

John R Craig

World J Otorhinolaryngol Head Neck Surg 2022 Mar 22;8(1):8-15. Epub 2022 Mar 22.

Department of Otolaryngology-Head and Neck Surgery Henry Ford Health System Detroit Michigan USA.

Odontogenic sinusitis (ODS) is more common than historically reported, and is underrepresented in the sinusitis literature. ODS is distinct from rhinosinusitis in that it is infectious sinusitis from an infectious dental source or a complication from dental procedures, and most commonly presents unilaterally. ODS clinical features, microbiology, and diagnostic and treatment paradigms are also distinct from rhinosinusitis. Read More

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Rhino-Orbital-Cerebral Mucormycosis in a Young Diabetic Patient with COVID-19 in Ethiopia: A Case Report.

Int Med Case Rep J 2022 19;15:251-257. Epub 2022 May 19.

Ophthalmologist, Department of Ophthalmology, MOH Eka Kotebe General Hospital, Addis Ababa, Ethiopia.

Background: There has been a rise in secondary invasive fungal infections reported in COVID-19 patients globally. We report the first published case of COVID-19 associated rhino-orbital-cerebral mucormycosis in Africa in a newly diagnosed diabetic female who presented with diabetic ketoacidosis (DKA) and discuss the prevalence and risk factors of fungal co-infection with the clinical presentation, diagnosis, and management of mucormycosis in COVID-19.

Case Presentation: A 39 years old female patient was admitted to ICU with a diagnosis of severe COVID-19 and newly diagnosed diabetes mellitus (DM) with DKA based on HgbA1c of 13. Read More

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[Treatment experience of recurrent allergic fungal rhinosinusitis: a case report].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2022 May;57(5):612-614

Department of Otorhinolaryngology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.

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Microbiology and outcome of pediatric orbital cellulitis in a Tertiary Eye Care Center in Saudi Arabia after the routine administration of Type B vaccine.

Saudi J Ophthalmol 2021 Jul-Sep;35(3):239-243. Epub 2022 Apr 18.

Department of Ophthalmology, Oculoplastic and Reconstructive Surgery Division, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.

Purpose: To evaluate the incidence of pediatric related orbital cellulitis after the routine administration of the vaccine in Saudi Arabia and to identify the most common pathogens, predisposing factors, related complications, and the need for surgical intervention.

Methods: A retrospective chart review was performed of patients with a discharge diagnosis of orbital cellulitis who presented to the King Abdul Aziz University Hospital, Riyadh, Saudi Arabia. Saudi children born between 2000 and 2016 were included. Read More

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Molecular analysis of dominant paranasal sinus bacteria in patients with and without chronic rhinosinusitis.

Arch Microbiol 2022 May 16;204(6):327. Epub 2022 May 16.

Microbial Biotechnology Research Center, Iran University of Medical Sciences, Tehran, Iran.

Recent studies have established the possible role of microbiota in developing various diseases. In this regard, attention has shifted to the evaluation of microbiota changes in the paranasal sinuses and its relationship to chronic rhinosinusitis (CRS), especially CRS with nasal polyposis (CRSwNP). This study aimed to examine the bacterial communities of the sphenoidal sinus in Iranian patients with and without CRS. Read More

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Arerugi 2022 ;71(3):195-199

Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine.

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MR imaging spectrum in COVID associated Rhino-Orbito-Cerebral mucormycosis with special emphasis on intracranial disease and impact on patient prognosis.

Eur J Radiol 2022 Jul 6;152:110341. Epub 2022 May 6.

Department of Ophthalmology, Maulana Azad Medical College and Guru Nanak Eye Centre, New Delhi 110002, India.

In the wake of the ongoing Coronavirus Disease 2019 (COVID-19) pandemic, a new epidemic of COVID associated mucormycosis (CAM) emerged in India. Early diagnosis and prompt treatment of this deadly disease are of paramount importance in improving patient survival. MRI is the cornerstone of diagnosis of early extrasinus disease, particularly intracranial complications which have traditionally been associated with a high mortality rate. Read More

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ACR Appropriateness Criteria® Sinonasal Disease: 2021 Update.

J Am Coll Radiol 2022 05;19(5S):S175-S193

Specialty Chair, Atlanta VA Health Care System and Emory University, Atlanta, Georgia.

This article presents guidelines for initial imaging utilization in patients presenting with sinonasal disease, including acute rhinosinusitis without and with suspected orbital and intracranial complications, chronic rhinosinusitis, suspected invasive fungal sinusitis, suspected sinonasal mass, and suspected cerebrospinal fluid leak. CT and MRI are the primary imaging modalities used to evaluate patients with sinonasal disease. Given its detailed depiction of bony anatomy, CT can accurately demonstrate the presence of sinonasal disease, bony erosions, and anatomic variants, and is essential for surgical planning. Read More

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Clinical Efficacy of Single Vidian Neurectomy in Chronic Rhinosinusitis with Nasal Polyps and Allergic Rhinitis.

J Coll Physicians Surg Pak 2022 May;32(5):618-622

Department of Otolaryngology-Head & Neck Surgery, Shanxi Medical University Second Affiliated Hospital, Taiyuan, China.

Objective: To investigate the clinical efficacy of single Vidian neurectomy (sVN) in the treatment of chronic rhinosinusitis with nasal polyps and allergic rhinitis (CRSwNP &AR).

Study Design: Descriptive study.   Place and Duration of Study: Otolaryngology-Head &Neck Surgery, Shanxi Medical University Second Affiliated Hospital, Taiyuan, China, February 2016 to February 2019. Read More

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Management of Fungal Rhinosinusitis: Experience From a Tertiary Care Centre in North India.

Cureus 2022 Apr 4;14(4):e23826. Epub 2022 Apr 4.

Department of Otorhinolaryngology & Head and Neck Surgery (ENT-HNS), Hamdard Institute of Medical Sciences and Research, Hakeem Abdul Hameed Centenary Hospital, New Delhi, IND.

Introduction Fungal rhinosinusitis (FRS) has increased over the past few decades due to the rampant use of antibiotics, steroids, immunosuppressive drugs, increased incidence of HIV and uncontrolled diabetes. The current study reviews the types, clinical presentation, microbiology, histopathology and outcomes related to FRS in a tertiary care center in North India. Methods We retrospectively reviewed the clinical and follow-up records of patients diagnosed with FRS over three years. Read More

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Misdiagnosis of fungal infections of the orbit.

Can J Ophthalmol 2022 May 4. Epub 2022 May 4.

From the Department of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa. Electronic address:

Objective: To evaluate the accuracy of the initial diagnosis in the case of fungal infections of the orbit and identify factors that may influence patient outcomes.

Methods: An institutional review board-approved retrospective chart review was conducted across 2 large academic centres to identify cases of fungal infections involving the orbit from January 1, 1998, to November 15, 2019. Data collected included patient demographics, past medical history, examination findings, diagnosis, treatment, imaging, and outcomes. Read More

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Differential susceptibility to SARS-CoV-2 in the normal nasal mucosa and in chronic sinusitis.

Eur J Immunol 2022 May 7. Epub 2022 May 7.

Department of Otolaryngology, Head and Neck Surgery, Tongji Hospital, School of Medicine, Tongji University, 389 Xincun Road, Putuo District, Shanghai, 200065, P. R. China.

Human nasal mucosa is susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and serves as a reservoir for viral replication before spreading to other organs (e.g. the lung and brain) and transmission to other individuals. Read More

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Successful Treatment of Optic Neuropathy Associated with Sphenoid Sinus Aspergillosis.

Ocul Immunol Inflamm 2022 May 6:1-3. Epub 2022 May 6.

Biomedical Research Institute, Pusan National University Hospital, Busan, South Korea.

Purpose: We report a case of optic neuropathy related to sphenoid sinus aspergillosis which showed good visual recovery with surgery and medical antifungal treatment.

Methods: Observational case study Case Presentation A 62-year-old man presented with decreased visual acuity in the right eye for 3 weeks. His visual acuity was counting fingers in the right eye and 20/20 in the left eye. Read More

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[Presentation and management of allergic fungal rhinosinusitis in children].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2022 Apr;36(4):247-252

Department of Otolaryngology Head and Neck Surgery,Children's Hospital Capital Institute of Pediatrics,Beijing,100020,China.

To assess the presentation of allergic fungal rhinosinusitis(AFRS) in children and the role of long-term comprehensive therapy of endoscopic surgery combined with drug therapy. The 3 children with AFRS were routinely examined by nasal endoscopy, CT scan, MRI scan and allergen detection before surgery, and mycological and histomathological examination were performed on the secretions in the sinus and the mucosa of the affected sinuses. All the 3 patients underwent endoscopic surgery, preoperative and postoperative treatment with oral and nasal corticosteroid, nasal irrigation, and individualized anti-allergy therapy and immunotherapy. Read More

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Chronic Granulomatous Invasive Fungal Sinusitis in Patients With Immunocompetence: A Review.

Otolaryngol Head Neck Surg 2022 May 3:1945998221097006. Epub 2022 May 3.

Department of Neurological Sciences, Christian Medical College Hospital, Vellore, India.

Objective: We aimed to study the literature on chronic granulomatous invasive fungal sinusitis to elucidate the changing trends in the management of the disease.

Data Sources: Using specific keywords, we searched the PubMed, PubMed Central, and Scopus databases over the past 50 years, which yielded 938 articles in the English language.

Review Methods: Scrutiny of 147 relevant articles revealed 15 homogenous case series (255 cases of histologically proven chronic granulomatous fungal sinusitis alone) and 8 heterogeneous case series (patients with other types of fungal sinusitis included), which were analyzed in detail (all with >5 cases each). Read More

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Dupilumab: An emerging therapy in allergic fungal rhinosinusitis.

World Allergy Organ J 2022 Mar 30;15(3):100638. Epub 2022 Mar 30.

Department of Ophthalmology, and Otolaryngology, Head and Neck Surgery, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.

Allergic fungal rhinosinusitis (AFRS) is a highly resistant disease and is challenging to treat. Patients with recurrent attacks of the disease despite surgical management can benefit from biologics as adjunct therapies. Dupilumab has shown promising endpoints in patients with chronic rhinosinusitis with nasal polyposis (CRSwNP). Read More

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