5,003 results match your criteria Sinusitis Acute


Prevalence and comorbidities of bronchiolitis in adults: A population-based study in South Korea.

Medicine (Baltimore) 2022 Jun 24;101(25):e29551. Epub 2022 Jun 24.

Department of Internal Medicine, Research Center for Pulmonary Disorders, Jeonbuk National University Medical School, Jeonju, South Korea.

Abstract: Bronchiolitis generally refers to inflammation and/or fibrosis of the non-cartilaginous small airways located approximately from the 8th airway generation down to the terminal and respiratory bronchioles. In contrast to young children, the frequency of small airway infection in adult bronchiolitis appears less frequent and a number of other pathophysiological conditions have been implicated in adult bronchiolitis. However, little information is available on the exact medical burden of bronchiolitis such as its prevalence and comorbidities in the adult population. Read More

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Endoscopic endonasal retrieval of air gun pellet retained in the frontal sinus: A case report.

Int J Surg Case Rep 2022 Jun 6;96:107280. Epub 2022 Jun 6.

Department of Otolaryngology-Head and Neck Surgery, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.

Introduction And Importance: Foreign bodies in paranasal sinuses are rarely encountered and most commonly present in the maxillary sinus. Guidelines for managing paranasal sinus object removal are limited due to its rarity. However, there are three major management options: open surgery, endoscopic sinus surgery, and observation. Read More

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-Cause of Nonspecific Acute Sinusitis: First Case Report and Review of Literature.

Microorganisms 2022 Jun 9;10(6). Epub 2022 Jun 9.

Department of Clinical Microbiology, Clinical Hospital Center Rijeka, Krešimirova 42, 51000 Rijeka, Croatia.

Although most sinus infections are viral, potential bacterial pathogens such as , and can migrate during a viral respiratory infection from the nasopharynx into the sinus cavity causing sinusitis. is a commensal of the external auditory canal and is considered one of the potential middle ear pathogens. Unlike most otopathogens, is rarely found in the nasopharynx of healthy individuals. Read More

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Intracranial complications of hypercoagulability and superinfection in the setting of COVID-19: illustrative cases.

J Neurosurg Case Lessons 2022 May 23;3(21):CASE22127. Epub 2022 May 23.

Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

Background: Hypercoagulability with thrombosis and associated inflammation has been well-documented in COVID-19, and catastrophic cerebral venous sinus thromboses (CVSTs) have been described. Another COVID-19-related complication is bacterial superinfection, including sinusitis. Here, the authors reported three cases of COVID-19-associated sinusitis, meningitis, and CVST and summarized the literature about septic intracranial thrombotic events as a cause of headache and fever in COVID-19. Read More

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Solitary Sphenoid Sinus Lesion Presenting as Chronic Headache.

J Craniofac Surg 2022 May;33(3):886-888

Department of Otolaryngology-Head and Neck Surgery, Kosin University College of Medicine, Busan, South Korea.

Background And Objectives: Headache is a common symptom with etiologies that are difficult to distinguish, 1 of which is sinusitis. A solitary sphenoid lesion, which is rare, can also cause acute or chronic headaches. The authors investigated whether endoscopic sinus surgery (ESS) for solitary sphenoid lesions could reduce headache symptoms. Read More

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[Analysis of relationship between distribution of pathogenic microorganisms in olfactory cleft and olfactory disorders among patients with upper respiratory inflammation during the prevention and control of COVID-19].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2022 Jun;57(6):683-691

Department of Otorhinolaryngology Head and Neck Surgery, Capital Institute of Pediatrics, Beijing 100020, China.

To explore the relationship between pathogens in the olfactory cleft area and olfactory disorders in patients with upper respiratory inflammation (URI) during the prevention and control of 2019 novel coronavirus disease (COVID-19). A total of 234 URI patients including acute upper respiratory infection, chronic rhinosinusitis (CRS), allergic rhinitis (AR) were continuously selected from September 2020 to March 2021 in Beijing Anzhen Hospital and 98 healthy adults were enrolled as controls. The secretions from the olfactory cleft of all subjects were collected with nasal swabs under nasal endoscopy. Read More

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Optimal Device and Regimen of Nasal Saline Treatment for Sinonasal Diseases: Systematic Review.

OTO Open 2022 Apr-Jun;6(2):2473974X221105277. Epub 2022 Jun 13.

Department of Otolaryngology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Objective: This review aimed to systematically determine the optimal nasal saline regimen for different types of sinonasal diseases.

Data Sources: PubMed, Embase, SCOPUS, Cochrane Library, Web of Science, ClinicalTrials.gov. Read More

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Specific antibody deficiency: Pearls and pitfalls for diagnosis.

Ann Allergy Asthma Immunol 2022 Jun 4. Epub 2022 Jun 4.

Department of Medicine - University of Virginia, Charlottesville, Virginia; Department of Microbiology - University of Virginia, Charlottesville, Virginia.

Objective: Specific antibody deficiency is an immune deficiency defined by the presence of normal quantitative levels of immunoglobulins but impaired antibody responses to polysaccharide antigens in patients presenting with frequent otosinopulmonary infections with pyogenic bacteria. This review summarizes the pitfalls associated with defining exactly what constitutes an "impaired" antibody response to polysaccharide antigens and the importance of documenting actual pyogenic infections before making a diagnosis of an immune deficiency.

Data Sources: PubMed review using the following words: specific antibody deficiency, pneumococcal vaccination, salmonella vaccination, infectious sinusitis Study Selection: This review focused on key studies that have been utilized to define what constitutes a "normal" humoral immune response to pneumococcal and salmonella vaccination in healthy subjects as well as published papers defining current expert opinion. Read More

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Telemedicine diagnosis of acute respiratory tract infection patients is not inferior to face-to-face consultation: a randomized trial.

Einstein (Sao Paulo) 2022 27;20:eAO6800. Epub 2022 May 27.

Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.

Objective: To analyze telemedicine diagnostic accuracy in patients with respiratory infections during COVID-19 pandemic compared to face-to-face evaluation in the emergency department.

Methods: Randomized, unicentric study between September 2020 and November 2020 in patients with any respiratory symptom (exclusion criteria: age >65 years, chronic heart or lung diseases, immunosuppressed). Patients were randomized 1:1 for brief telemedicine followed by face-to-face consultation or direct face-to-face evaluation. Read More

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Disseminated fusariosis with cerebral involvement in a patient with acute myeloid leukemia: Successful outcome with intrathecal -and systemic antifungal treatment.

J Infect Chemother 2022 May 28. Epub 2022 May 28.

Department of Infectious Medicine, Rigshospitalet, Copenhagen, Denmark.

The outcome of invasive fusariosis in hematological patients is usually dismal, particularly in patients with persistent neutropenia. We report a patient with acute myeloid leukemia (AML) with Fusarium dimerum sinusitis with hematogenic dissemination to the brain. Despite surgical debridements of the sinuses and liposomal amphotericin B, voriconazole and terbinafine, there was progression with cerebral involvement after recovery of neutropenia and with detection of F. Read More

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The Role of Seawater and Saline Solutions in Treatment of Upper Respiratory Conditions.

Mar Drugs 2022 May 17;20(5). Epub 2022 May 17.

"Andrija Štampar" School of Public Health, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.

The history of saline nasal irrigation (SNI) is indeed a long one, beginning from the ancient Ayurvedic practices and gaining a foothold in the west at the beginning of the 20th century. Today, there is a growing number of papers covering the effects of SNI, from in vitro studies to randomized clinical trials and literature overviews. Based on the recommendations of most of the European and American professional associations, seawater, alone or in combination with other preparations, has its place in the treatment of numerous conditions of the upper respiratory tract (URT), primarily chronic (rhino)sinusitis, allergic rhinitis, acute URT infections and postoperative recovery. Read More

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Intraoperative complications and early implant failure after transcrestal sinus floor elevation with residual bone height ≤5 mm: A retrospective multicenter study.

Clin Oral Implants Res 2022 May 16. Epub 2022 May 16.

University of Bern, Bern, Switzerland.

Objective: Clinical indications for maxillary sinus floor elevation with transcrestal techniques have increased in recent years even in sites with minimal residual bone height (RBH). Nevertheless, limited information is currently available on incidence of intraoperative complications and early implant failure in these cases.

Material And Methods: This retrospective multicenter study was performed on anonymized clinical and radiographic records of patients who underwent transcrestal sinus floor elevation in seven clinical centers. Read More

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ACR Appropriateness Criteria® Sinonasal Disease: 2021 Update.

J Am Coll Radiol 2022 05;19(5S):S175-S193

Specialty Chair, Atlanta VA Health Care System and Emory University, Atlanta, Georgia.

This article presents guidelines for initial imaging utilization in patients presenting with sinonasal disease, including acute rhinosinusitis without and with suspected orbital and intracranial complications, chronic rhinosinusitis, suspected invasive fungal sinusitis, suspected sinonasal mass, and suspected cerebrospinal fluid leak. CT and MRI are the primary imaging modalities used to evaluate patients with sinonasal disease. Given its detailed depiction of bony anatomy, CT can accurately demonstrate the presence of sinonasal disease, bony erosions, and anatomic variants, and is essential for surgical planning. Read More

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Clinical Efficacy of Single Vidian Neurectomy in Chronic Rhinosinusitis with Nasal Polyps and Allergic Rhinitis.

J Coll Physicians Surg Pak 2022 May;32(5):618-622

Department of Otolaryngology-Head & Neck Surgery, Shanxi Medical University Second Affiliated Hospital, Taiyuan, China.

Objective: To investigate the clinical efficacy of single Vidian neurectomy (sVN) in the treatment of chronic rhinosinusitis with nasal polyps and allergic rhinitis (CRSwNP &AR).

Study Design: Descriptive study.   Place and Duration of Study: Otolaryngology-Head &Neck Surgery, Shanxi Medical University Second Affiliated Hospital, Taiyuan, China, February 2016 to February 2019. Read More

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Management of Fungal Rhinosinusitis: Experience From a Tertiary Care Centre in North India.

Cureus 2022 Apr 4;14(4):e23826. Epub 2022 Apr 4.

Department of Otorhinolaryngology & Head and Neck Surgery (ENT-HNS), Hamdard Institute of Medical Sciences and Research, Hakeem Abdul Hameed Centenary Hospital, New Delhi, IND.

Introduction Fungal rhinosinusitis (FRS) has increased over the past few decades due to the rampant use of antibiotics, steroids, immunosuppressive drugs, increased incidence of HIV and uncontrolled diabetes. The current study reviews the types, clinical presentation, microbiology, histopathology and outcomes related to FRS in a tertiary care center in North India. Methods We retrospectively reviewed the clinical and follow-up records of patients diagnosed with FRS over three years. Read More

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Differential susceptibility to SARS-CoV-2 in the normal nasal mucosa and in chronic sinusitis.

Eur J Immunol 2022 May 7. Epub 2022 May 7.

Department of Otolaryngology, Head and Neck Surgery, Tongji Hospital, School of Medicine, Tongji University, 389 Xincun Road, Putuo District, Shanghai, 200065, P. R. China.

Human nasal mucosa is susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and serves as a reservoir for viral replication before spreading to other organs (e.g. the lung and brain) and transmission to other individuals. Read More

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Photodynamic therapy of adenoid hypertrophy in acute rhinosinusitis.

Photodiagnosis Photodyn Ther 2022 Apr 29;39:102892. Epub 2022 Apr 29.

Department of Biomedical Engineering, Texas A&M University, USA; São Carlos Institute of Physics, University of São Paulo, São Carlos, Brazil.

A first step for microorganisms to reach the respiratory system and cause infectious disease is colonization in the nasopharynx. Humans inhale a bacterial load of up to 10 per cubic meter of air per day [1], including transient microorganisms between the upper and lower airways. This can lead to lung infections, amounting to billions of dollars in annual direct treatment costs in the United States, depending on the etiologic agent [2,3]. Read More

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Orbital Complications of Acute Sinusitis in Pediatric Patients: Management of Chandler III Patients.

Allergy Rhinol (Providence) 2022 Jan-Dec;13:21526575221097311. Epub 2022 Apr 27.

Department of Otolaryngology-Head and Neck Surgery, Indianapolis, IN, USA.

Background: Surgery is often avoided in the setting of pediatric orbital complications from acute sinusitis unless necessitated by alarming ophthalmological signs. Criteria for surgical intervention are not well-defined.

Objective: We aim to review our experiences, management practices and patient outcomes over a ten-year period for Chandler III patients. Read More

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[Diagnosis and treatment of subperiosteal orbital abscess].

Ugeskr Laeger 2022 Apr;184(17)

Øre-, Næse-, Halskirurgi, Aarhus Universitetshospital.

Subperiosteal orbital abscess is a complication of acute bacterial sinusitis. In this review, we summarise the theoretical background and highlight the importance of a fast diagnostic workup. The treatment of acute sinusitis with involvement of an eye is antibiotic therapy and daily evaluation by both an ophtalmologist and a rhinologist. Read More

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Antibiotic prescribing for respiratory tract infection across a national primary care network in 2019.

Can Commun Dis Rep 2022 Apr 6;48(4):157-163. Epub 2022 Apr 6.

Sunnybrook Health Sciences Centre, Toronto, ON.

Background: Respiratory tract infection (RTI) is the leading reason for avoidable antimicrobial use in primary care, yet provider-level feedback on its use is only available in some provinces. The aim of this study was to validate case definitions for RTI across the Canadian Primary Care Sentinel Surveillance Network (CPCSSN) and determine baseline provider-level variability in antimicrobial prescribing in 2019.

Methods: The RTI case definitions were developed using demographic, diagnostic coding and keywords in electronic medical record. Read More

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A comparative study on the clinical profile of COVID-related and non-COVID-related acute invasive fungal rhino sinusitis.

Eur Arch Otorhinolaryngol 2022 Apr 27. Epub 2022 Apr 27.

Department of ENT, Head and Neck Surgery, St. Stephen's Hospital, Delhi, 110054, India.

Purpose: To compare the clinical profile of COVID-related and non-COVID-related rhino-orbito-cerebral invasive fungal disease.

Methods: We have compared the comorbidities, clinical features, course of the disease and outcome between COVID-related and non-COVID-related acute invasive fungal rhinosinusitis (AIFRS) of the rhino-orbito-cerebral form.

Results: HbA1c and blood sugar at the time of admission were significantly higher in the non-COVID group (P < 0. Read More

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Analysis of acute sinusitis-related early failed implant surface: a combined histological, electron microscopy, and X-ray spectroscopy approach.

Maxillofac Plast Reconstr Surg 2022 Apr 26;44(1):18. Epub 2022 Apr 26.

Department of Oral and Maxillofacial Surgery, Dental Research Institute, School of Dentistry, Seoul National University, 101 Daehak-ro, Jongno-gu, Seoul, 03080, South Korea.

Background: Even though dental implants are a reliable choice for dental rehabilitation, implant failures due to various etiologies have been reported. Early implant failures account for 2 to 6% of installed implants and are reported to have a higher rate than late failures, regardless of loading time. We herein report three cases of acute sinusitis and early implant failure with implants that failed within 1 month after installation. Read More

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Healthcare Costs for Pneumococcal Disease in the Era of Infant Immunization With 13-Valent Pneumococcal Conjugate Vaccine: A Population-Based Study.

Value Health 2022 Apr 21. Epub 2022 Apr 21.

Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, BC, Canada; School of Population and Public Health, Faculty of Medicine, The University of British Columbia, Vancouver, BC, Canada. Electronic address:

Objectives: Invasive pneumococcal disease (IPD) and a variety of clinical syndromes caused by pneumococci, such as acute otitis media (AOM), acute sinusitis (AS), and community-acquired pneumonia (CAP), cause a substantial burden on healthcare systems. Few studies have explored the short-term financial burden of pneumococcal disease after the 13-valent pneumococcal conjugate vaccine (PCV13) introduction in the infant immunization programs. This population-based study evaluated changes in costs associated with healthcare utilization for pneumococcal disease after the PCV13 introduction in the infant immunization program in British Columbia, Canada. Read More

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TiO-DNA Nanosensor In Situ for Quick Detection of Nasal Flora in Allergic Rhinitis Patients.

Comput Math Methods Med 2022 13;2022:5708326. Epub 2022 Apr 13.

Ear-Nose-Throat Department, Longyan First Hospital Affiliated to Fujian Medical University, Longyan, Fujian 364000, China.

Background: A relevant study found that allergic rhinitis (AR) may be related to the imbalance of nasal flora. Therefore, if the nasal flora of AR patients can be detected quickly, it is of great significance to study the distribution law of nasal flora in AR patients and explore its correlation with AR.

Objective: To design a new and convenient nano-DNA sensor for quick screening of nasal flora in allergic rhinitis (AR) patients, so as to provide experimental basis for the prevention and treatment of AR. Read More

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Real-Life Effectiveness of Benralizumab, Mepolizumab and Omalizumab in Severe Allergic Asthma Associated with Nasal Polyps.

Clin Rev Allergy Immunol 2022 Apr 14. Epub 2022 Apr 14.

Department of Respiratory Medicine, University Hospital of Santiago de Compostela, Santiago de Compostela, Spain.

Biological therapies are available for the treatment of the severe allergic asthma (SAA) with blood eosinophil count ≥ 0.3 × 10/L. Several of them also showed benefits on nasal polyps (NP), one of the most frequent comorbidities of the severe asthma, but comparative studies on their effectiveness in the association SAA-NP are currently lacking. Read More

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Management options for orbital complications of acute rhinosinusitis in pediatric patients.

Am J Otolaryngol 2022 May-Jun;43(3):103452. Epub 2022 Apr 6.

Department of Otolaryngology, Hospital Universitario Central de Asturias, Oviedo, Spain; University of Oviedo, Instituto de Investigación Sanitaria del Principado de Asturias, IUOPA, CIBERONC, Oviedo, Spain.

Objectives: Acute bacterial rhinosinusitis (ABRS) is a common pediatric condition. Despite its tendency to heal without complications, orbital complications (OC) are seen in 6% of patients and can cause vision impairment and put life at risk. Current treatment of this complications involves systemic antibiotics with or without surgical drainage, remaining controversial the use of corticosteroids. Read More

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The Microbiology of Acute Exacerbations in Chronic Rhinosinusitis - A Systematic Review.

Front Cell Infect Microbiol 2022 24;12:858196. Epub 2022 Mar 24.

Department of Otolaryngology Head and Neck Surgery, Columbia University, New York City, NY, United States.

Background: Acute exacerbations (AE) in chronic rhinosinusitis (CRS) are a common and important clinical issue. However, relatively little is known regarding the underlying microbiology that drives exacerbations or how it relates to the microbiome of CRS. The purpose of this study is to examine the literature to characterize the microbiome associated with acute exacerbations in a chronic rhinosinusitis setting. Read More

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New treatment options for acute rhinosinusitis according to EPOS 2020.

Otolaryngol Pol 2021 Dec;76(1):29-39

Department of Otolaryngology and Laryngological Oncology with Clinical Department of Craniomaxillofacial Surgery, Military Medical Institute, Warsaw, Poland.

Acute rhinosinusitis (ARS) is a very common condition and mostly of viral origin. About 0.5-2% of the viral ARS are complicated by a bacterial infection. Read More

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December 2021

Molecular evidence of upper and lower respiratory infection due to in a post-kidney transplantation patient.

Clin Case Rep 2022 Feb 20;10(2):e05492. Epub 2022 Feb 20.

Toxoplasmosis Research Center Communicable Diseases Institute Iranian National Registry Center for Lophomoniasis (INRCL) Imam Khomeini Hospital Mazandaran University of Medical Sciences Sari Iran.

We report a case of lophomoniasis in a kidney post-transplantation patient. The patient, 46-year-old man, had pneumonia, acute sinusitis, and tonsillitis on admission. We recommend that lophomoniasis should be essentially ruled out in all patients suffering from post-transplantation infection, particularly in those who do not respond to routine antibiotic regimens. Read More

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February 2022

Changing Trends in the Survival of Immunosuppressed Children with Invasive Fungal Rhinosinusitis.

Am J Rhinol Allergy 2022 Mar 31:19458924221090915. Epub 2022 Mar 31.

Sackler Faculty of Medicine, 26745Tel Aviv University, Tel Aviv, Israel.

Background: Acute invasive fungal rhinosinusitis has been associated with high mortality rates.

Objective: We aimed to explore the contribution of novel detection and treatment methods on the outcome of immunosuppressed children with acute invasive fungal rhinosinusitis.

Methods: The records of all children with a hematologic or oncologic disease who developed acute invasive fungal rhinosinusitis between 2005-2020 were reviewed. Read More

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