28,328 results match your criteria Sinusitis

Assessment of the necessity of frontal sinostomy in cases of frontal sinusitis associated with fungus ball of the maxillary sinus.

Eur Arch Otorhinolaryngol 2021 Jun 15. Epub 2021 Jun 15.

Department of Otorhinolaryngology Head and Neck Surgery, First Affiliated Hospital of Anhui Medical University, Jixi Road 218, Hefei, 230022, Anhui, China.

Purpose: This study was conducted to evaluate outcomes in patients presenting with fungus ball of the maxillary sinus (MSFB) and frontal sinusitis who were treated via middle meatal antrostomy alone.

Methods: This was a randomized, controlled study with a parallel group design. Patients with MSFB and frontal sinusitis were randomly assigned to the maxillary middle meatal antrostomy (MMMA) or control (MMMA + frontal sinusotomy) groups. Read More

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Transpalpebral frontal sinus septectomy (with video).

Eur Ann Otorhinolaryngol Head Neck Dis 2021 Jun 11. Epub 2021 Jun 11.

APHM, La Conception University Hospital, Department of Oto-Rhino-Laryngology and Head and Neck Surgery, 147, Bvd Baille, 13005 Marseille, France; Aix Marseille Univ, CNRS, IUSTI, Marseille, France.

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Clinical experience and treatment approaches in sinonasal osteomas from a Tertiary Care Hospital in Turkey.

Auris Nasus Larynx 2021 Jun 11. Epub 2021 Jun 11.

Department of Otorhinolaryngology, Faculty of Medicine Kocaeli University, Kocaeli, Turkey.

Objective: Osteomas are slow-growing benign osseous tumors that particularly located in the paranasal sinuses (PS). Here, we aimed to define the clinical symptoms and features, diagnostic conditions caused by osteomas located in four different PSs, to evaluate the surgical indications and methods, to compare the factors that can affect the surgical decision, radiological findings, and prognosis.

Methods: The data of patients with paranasal sinus lesions and diagnosed as osteoma according to the radiological imaging, who applied to our clinic between 2010 and 2020, were retrospectively collected and re-evaluated in the light of clinical, radiological, and pathological data. Read More

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Review on Pneumococcal Infection in Children.

Cureus 2021 May 9;13(5):e14913. Epub 2021 May 9.

Paediatrics, Base Hospital, Mahaoya, LKA.

Childhood pneumococcal infection is a growing concern among paediatricians especially, in countries where there is no routine vaccination program against . The disease is associated with significant morbidity and mortality in young children particularly those who are under the age of two years. Its main virulent factors include polysaccharide capsule, autolysin, pneumolysin, choline-binding Protein A, the higher chance for genetic transformation, and the presence of pilli that facilitate enhanced binding of bacteria to host cellular surfaces. Read More

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Choosing the Right Patient for Biologic Therapy in Chronic Rhinosinusitis with Nasal Polyposis: Endotypes, Patient Characteristics, and Defining Failures of Standard Therapy.

Otolaryngol Clin North Am 2021 Jun 8. Epub 2021 Jun 8.

Department of Otolaryngology-Head and Neck Surgery, 800 Harrison Avenue BCD5, Boston, MA 02118, USA.

There are many phenotypes of chronic sinusitis and clinical variables that differ between patients. The ability to accurately diagnose, predict prognosis, and select the appropriate treatment depends on the understanding of disease endotypes. Chronic sinusitis is in the early stages of disease endotyping. Read More

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Outcomes of a Modified Treatment Ladder Algorithm using Retrobulbar Amphotericin B for Invasive Fungal Rhino-Orbital Sinusitis.

Am J Ophthalmol 2021 Jun 8. Epub 2021 Jun 8.

Department of Ophthalmology, University of California San Francisco, California, United States of America. Electronic address:

Purpose: To assess whether a modified treatment ladder algorithm incorporating transcutaneous retrobulbar amphotericin B (TRAMB) for invasive fungal rhino-orbital sinusitis (IFROS) can reduce the risk of exenteration without compromising survival.

Design: Retrospective, comparative clinical study with historical controls.

Methods: Fifty consecutive patients with biopsy-proven invasive fungal sinusitis and radiographic evidence of orbital involvement were evaluated at a single tertiary institution from 1999-2020. Read More

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Upper airway cough syndrome may be the main cause of chronic cough in Japan: a cohort study.

Kimihiko Yasuda

Fam Pract 2021 Jun 11. Epub 2021 Jun 11.

Yasuda Clinic, Internal Medicine, 2-2-20-2F, Takasago, Urawa-ku, Saitama-shi, Saitama, 330-0063, Japan.

Background: Upper airway cough syndrome (UACS) is generally considered a common cause of chronic cough but remains poorly recognised in Japan.

Objective: This study aimed to assess whether UACS was a common cause of chronic cough in Japan, as is true in other countries. Interview and examination items were evaluated for their potential use in UACS diagnosis. Read More

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Actinomycosis of the nasal cavity.

Braz J Otorhinolaryngol 2021 May 25. Epub 2021 May 25.

Chonnam National University Medical School & Hwasun Hospital, Department of Otolaryngology-Head and Neck Surgery, Hwasun, South Korea.

Introduction: Actinomycosis of the nasal cavity is very rare.

Objective: The purpose of this study was to investigate the clinical features, treatment methods, and treatment results of actinomycosis of the nasal cavity in our hospital.

Methods: We retrospectively enrolled 11 patients with histopathologically identified actinomycosis of the nasal cavity from January 2010 to May 2020. Read More

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Prevalence of allergic fungal sinusitis among patients with nasal polyposis.

J Pak Med Assoc 2021 Jun;71(6):1605-1607

Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.

Objective: To determine the frequency of allergic fungal sinusitis among patients with nasal polyps, and to compare Lund-Mackay scores of patients with and without allergic fungal sinusitis.

Methods: The cross-sectional longitudinal study was conducted at a tertiary healthcare centre in Karachi, Pakistan, from December 2016 to November 2018, and comprised patients with sinonasal polyposis undergoing surgery. The patients were categorised as having allergic fungal sinusitis when histopathology showed allergic mucin with fungal hyphae and culture was positive for fungal growth. Read More

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Eosinophilic Granulomatosis with Polyangiitis Presenting as Unilateral Acute Anterior Ischaemic Optic Neuropathy.

Neuroophthalmology 2021 25;45(2):109-116. Epub 2020 Jun 25.

Birmingham Neuro-Ophthalmology, Queen Elizabeth Hospital, Birmingham, UK.

Eosinophilic granulomatosis with polyangiitis (eGPA) is a rare vasculitis of small-medium sized vessels that can cause both anterior and posterior ischaemic optic neuropathies. Herein, the authors present a rare case of eGPA presenting initially as an acute unilateral anterior ischaemic optic neuropathy from short posterior ciliary artery vasculitis. The diagnosis presented a challenge as clinical and histopathological evidence suggested allergic rhinosinusitis, and no invasive fungal sinusitis was found. Read More

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Cerebral sinovenous thrombosis in children: A single-center experience.

Turk Arch Pediatr 2021 1;56(3):236-244. Epub 2021 May 1.

Department of Child Health and Diseases, Department of Child Neurology, Ege University School of Medicine, İzmir, Turkey.

Objective: The study aimed to evaluate the patients with a diagnosis of cerebral sinovenous thrombosis in terms of clinical findings, etiology and underlying risk factors, imaging findings, treatment, and prognosis in the long term.

Materials And Methods: Medical records of 19 patients whose ages ranged between 0 days and 17 years with clinical and radiological cerebral sinovenous thrombosis in Ege University Department of Child Neurology were retrospectively evaluated.

Results: Nine of nineteen cases were female (47. Read More

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Pattern of symptom improvement following endoscopic sinus surgery for chronic rhinosinusitis.

BMC Surg 2021 Jun 8;21(1):288. Epub 2021 Jun 8.

Division of Epidemiology and Biostatistics, Department of Family and Community Medicine, College of Medicine, Imam Abdulrahman Bin Faisal University, Al Khobar, Saudi Arabia.

Background: Chronic rhinosinusitis (CRS) is a common inflammation of the nose and the paranasal sinuses. Intractable CRS cases are generally treated with endoscopic sinus surgery (ESS). Although the effect of ESS on CRS symptoms has been studied, the pattern of symptom improvement after ESS for CRS is yet to be investigated. Read More

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[Intravenous immunoglobulin replacement therapy in 114 cases of congenital agammaglobulinemia].

Zhonghua Er Ke Za Zhi 2021 Jun;59(6):495-500

Department of Rheumatology and Immunology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Developmental and Disorders, Chongqing Key Laboratory of Child Infection and Immunity, Chongqing 400014, China.

To analyze the clinical characteristics of congenital agammaglobulinemia and the efficacy of intravenous immunoglobulin (IVIG) replacement therapy for this disease. The basic characteristics, clinical manifestations, laboratory examinations, and outcomes of 114 patients with congenital agammaglobulinemia diagnosed in Children's Hospital of Chongqing Medical University from January 1988 to April 2020 were retrospectively analyzed. The efficacy of IVIG in improving the clinical symptoms between regular and irregular treatment groups were compared by χ test. Read More

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Comparison of Therapeutic Effects and Olfactory Function of Oral Glucocorticoid and Intranasal Glucocorticoid on Chronic Rhinosinusitis Patients with Nasal Polyps.

Quan Yang Min Li

J Coll Physicians Surg Pak 2021 Jun;30(6):699-702

Department of Otolaryngology, Suzhou Hospital of Integrated Traditional Chinese and Western Medicine, China.

Objective: To compare the therapeutic effects and olfactory function of oral glucocorticoid and intranasal glucocorticoid in patients with chronic rhinosinusitis (CRS) with nasal polyps.

Study Design: Experimental study.

Place And Duration Of Study: Suzhou Hospital of Integrated Traditional Chinese and Western Medicine, from January 2018 to November 2019. Read More

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Immediate and delayed antibiotic prescribing strategies used by Australian early-career general practitioners.

Br J Gen Pract 2021 Jun 4. Epub 2021 Jun 4.

The University of Newcastle School of Medicine and Public Health, Callaghan, Australia.

Background: Antibiotics are overused for non-pneumonia acute respiratory tract infections (ARTIs).

Aim: To establish prevalence and explore associations of antibiotic prescribing strategies used by Australian early-career GPs for non-pneumonia ARTIs.

Design And Setting: Cross-sectional analysis of data, September 2016 to December 2017, from the Registrar Clinical Encounters in Training cohort study. Read More

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Medical and surgical treatment of rhino-orbital-cerebral mucormycosis in a child with leukemia.

Am J Ophthalmol Case Rep 2021 Jun 16;22:101092. Epub 2021 Apr 16.

Department of Ophthalmology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

Purpose: Rhino-orbital-cerebral mucormycosis (ROCM) is a rare opportunistic infection with a high mortality despite relevant treatment.

Observations: A 3-year-old girl under treatment for acute lymphoblastic leukemia developed periorbital swelling, ophthalmoplegia and a necrotic palatal lesion during a period of neutropenia. Imaging revealed sinusitis, pre- and postseptal cellulitis. Read More

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Imaging spectrum of acute invasive fungal rhino-orbital-cerebral sinusitis in COVID-19 patients: A case series and a review of literature.

J Neuroradiol 2021 Jun 1. Epub 2021 Jun 1.

Ain Shams University, Faculty of Medicine, Department of Otolaryngology, Cairo, Egypt. Electronic address:

Background: The incidence of devastating opportunistic coinfections in patients with COVID-19 infection, their imaging features and their morbidity and mortality consequences need to be unraveled.

Methods: This is a case series presenting the radiologic features and clinical presentation of acute invasive fungal rhino-orbital-cerebral sinusitis (AIFS) in eight hospitalized patients with confirmed COVID-19 infection.

Results: Our patient cohort presented with symptoms of the invasive fungal disease within 12-35 days from their initial presentation with COVID-19 infection. Read More

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Screening in cryptogenic brain abscess: Do not forget pulmonary arteriovenous malformations.

Surg Neurol Int 2021 26;12:188. Epub 2021 Apr 26.

Department of Neurosurgery, AZ Klina, Brasschaat, Belgium.

Background: Brain abscess usually occurs secondary to trauma, through contiguous spread (e.g.; dental infections, [paranasal] sinusitis, otitis, and mastoiditis), after intracranial neurosurgical procedures, or through hematogenous spread in case of an arteriovenous (AV) shunt, for example; atrial septum defect. Read More

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Iatrogenic Cushing's syndrome as a consequence of nasal use of Betamethasone spray during pregnancy.

Acta Endocrinol (Buchar) 2020 Oct-Dec;16(4):511-517

"C.I.Parhon" National Institute of Endocrinology - Neuroendocrinology, Bucharest, Romania.

Introduction: Glucocorticoids (GC) are largely used for their anti-inflammatory and immunosuppressive effects. Until recently "local" administration (inhalation, topical, intra-articular, ocular and nasal) was considered devoid of important systemic side effects, but there is no administration form, dosing or treatment duration for which the risk of iatrogenic Cushing's syndrome (CS) and consequent adrenal insufficiency (AI) can be excluded with certainty.

Patients And Methods: We present the case of a pregnant woman who developed overt CS with secondary AI in the second trimester of pregnancy. Read More

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Revisiting the controversy: The role of fungi in chronic rhinosinusitis.

Int Forum Allergy Rhinol 2021 Jun 2. Epub 2021 Jun 2.

Department of Otorhinolaryngology-Head and Neck Surgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, USA.

In the last two decades, the development of culture-independent genomic techniques has facilitated an increased appreciation of the microbiota-immunity interactions and their role in a multitude of chronic inflammatory diseases such as chronic rhinosinusitis (CRS), asthma, inflammatory bowel disease and dermatitis. While the pathologic role of bacteria in chronic inflammatory diseases is generally accepted, the understanding of the role of fungi remains controversial. Chronic rhinosinusitis, specifically the phenotype linked to nasal polyps, represents a spectrum of chronic inflammatory diseases typically characterized by a type 2 immune response. Read More

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Central compartment atopic disease: outcomes compared with other subtypes of chronic rhinosinusitis with nasal polyps.

Int Forum Allergy Rhinol 2021 Jun 2. Epub 2021 Jun 2.

Department of Otolaryngology-Head and Neck Surgery, Emory University School of Medicine, Atlanta, Georgia, USA.

Background: Central compartment atopic disease (CCAD) is a variant of chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) characterized by polypoid changes of the superior nasal septum, middle (MT), and/or superior turbinates (ST). This study evaluates surgical outcomes in patients with CCAD compared with other CRSwNP subtypes.

Methods: Retrospective analysis was performed at Emory University from May 2012 to November 2019. Read More

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Pseudoephedrine-Benefits and Risks.

Int J Mol Sci 2021 May 13;22(10). Epub 2021 May 13.

Department of Clinical Pharmacology, Wroclaw Medical University, Borowska 211a St., 50-556 Wroclaw, Poland.

Pseudoephedrine (PSE) is a drug with a long history of medical use; it is helpful in treating symptoms of the common cold and flu, sinusitis, asthma, and bronchitis. Due to its central nervous system (CNS) stimulant properties and structural similarity to amphetamine, it is also used for non-medical purposes. The substance is taken as an appetite reducer, an agent which eliminates drowsiness and fatigue, to improve concentration and as a doping agent. Read More

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School Nurses on the Front Lines of Healthcare: Getting aHEAD of EmergENT Eye, Ear, Nose, and Throat Infections.

NASN Sch Nurse 2021 Jun 1:1942602X211019109. Epub 2021 Jun 1.

Professor, Departments of Emergency Medicine and Pediatrics, Penn State College of Medicine, Attending Pediatric Emergency Medicine physician, Penn State Hershey Medical Center, Hershey, PA.

School nurses may deal with various common infectious eye, ear, nose, and throat-related chief complaints in regular practice. Recognizing the signs and symptoms of severe infection is paramount to preventing life-threatening complications that can have both acute and long-term implications. Distinguishing urgent and emergent eye, ear, nose, and throat conditions to send to the emergency department is integral to reducing the morbidity associated with these conditions. Read More

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Anatomical Features Around Eustachian Tube in Eosinophilic Otitis Media With Eosinophilic Sinusitis.

Laryngoscope 2021 Jun 1. Epub 2021 Jun 1.

Department of Otorhinolaryngology, Omori Medical Center, Toho University, Tokyo, Japan.

Objectives/hypothesis: This study investigated the relationships between anatomical findings around the eustachian tube (ET) and eosinophilic otitis media (EOM) accompanied by eosinophilic chronic rhinosinusitis (ECRS).

Study Design: This study employed axial, coronal, sagittal and oblique computed tomography.

Methods: Patients who underwent endoscopic sinus surgery at the Department of Otolaryngology, Toho University Medical Center Omori Hospital and were diagnosed with ECRS (106 patients) based on the Japanese Epidemiological Survey of Refractory Eosinophilic Chronic Rhinosinusitis study were included. Read More

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ENT and dentist cooperation in the management of odontogenic sinusitis. A review.

Acta Otorhinolaryngol Ital 2021 Apr;41(Suppl. 1):S116-S123

Head and Neck Department, ASST Santi Paolo e Carlo, Department of Health Sciences, Università degli Studi di Milano, Milan, Italy.

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Surgical multidisciplinary approach of orbital complications of sinonasal inflammatory disorders.

Acta Otorhinolaryngol Ital 2021 Apr;41(Suppl. 1):S108-S115

Neuroradiology Department, Nuovo Ospedale Civile Sant'Agostino Estense, Modena, Italy.

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A computed tomographic study of endodontic and apical changes in 81 equine cheek teeth with sagittal fractures.

Equine Vet J 2021 Jun 1. Epub 2021 Jun 1.

Royal Veterinary College, Equine Referral Hospital, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire, AL9 6TA, UK.

Background: Sagittal fractures of equine cheek teeth are commonly observed during oral examination. There are few reports on the apical and endodontic pathology associated with such fractures seen during computed tomographic (CT) examination.

Objectives: To document the prevalence of CT changes indicative of apical disease in equine cheek teeth which have suffered a sagittal fracture involving the clinical +/- reserve crown. Read More

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Health behaviors and multimorbidity associated with bruxism: Population-based study.

Oral Dis 2021 May 31. Epub 2021 May 31.

Department of Public Health, School of Medical Sciences, University of Campinas-UNICAMP, Campinas, Brazil.

Objectives: Determine the prevalence of possible bruxism in the adult population of Campinas, Brazil, and investigate its association with health behaviors, health status, and multimorbidity.

Methods: A population-based cross-sectional study was conducted with data from the 2014/2015 Campinas Health Survey. The sample was composed of 1986 adults (≥20 years of age). Read More

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A novel mutation in TNFRSF11A gene causes pediatric osteopetrosis: case report.

BMC Surg 2021 May 28;21(1):269. Epub 2021 May 28.

Department of Otolaryngology, Head & Neck Surgery, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, 610091, China.

Background: Osteopetrosis is a rare inherited bone disorder affected individual by osteoclast disfunction and increasing bone density. Surgery was taken for histological examination of the specimen and evidence of malignancy was not found. Finally, X-ray and gene detection lead to the diagnosis. Read More

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Sinonasal polyposis complicated with extradural abscess and lateral rectus palsy.

BMJ Case Rep 2021 May 26;14(5). Epub 2021 May 26.

ENT & Head and neck surgery, All India Institute of Medical Sciences, New Delhi, India.

Sinogenic intracranial and orbital complications are infrequent complications of chronic rhinosinusitis with nasal polyposis (CRSwNP), leading to potentially fatal intracranial and orbital sequelae. The mortality and morbidity associated with these complications remain high despite the widespread use of antibiotics. We report a patient with CRSwNP presenting with acute onset extradural empyema and sixth nerve palsy in whom the diagnosis was delayed, necessitating early surgical intervention. Read More

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