5,051 results match your criteria Sinus Bradycardia


Left main coronary artery vasospasm: A case report of misdiagnosed severe coronary artery disease.

Ann Med Surg (Lond) 2022 Jun 29;78:103691. Epub 2022 Apr 29.

Department of Medicine, Division of Cardiology, Creighton University School of Medicine, Omaha, NE, USA.

Introduction And Importance: Left main coronary artery (LMCA) vasospasm is rare and can cause demand-supply mismatch that can mimic coronary artery disease (CAD). This could lead to misdiagnosis and inappropriate referral for surgical intervention.

Case Presentation: A 55-year-old woman with no cardiac risk factors presented with anginal chest pain. Read More

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Implantable loop recorder as a strategy following cardiovascular implantable electronic device extraction without reimplantation.

Pacing Clin Electrophysiol 2022 May 19. Epub 2022 May 19.

Division of Cardiology, Department of Medicine, Cardiovascular Institute, University of California San Diego, La Jolla, CA, USA.

Background: Limited data exists for outcomes in patients undergoing cardiovascular implantable electronic device (CIED) transvenous lead extraction (TLE) without clear indications for device reimplantation. The implantable loop recorder (ILR) may be an effective strategy for continuous monitoring in select individuals.

Objective: This retrospective analysis aims to investigate patients who have undergone ILR implant following TLE without CIED reimplantation. Read More

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DURABILITY OF LEFT BUNDLE BRANCH AREA PACING.

J Cardiovasc Electrophysiol 2022 May 18. Epub 2022 May 18.

Department of Electrophysiology, Lehigh Valley Heart Institute, Allentown, PA.

Background: Left bundle branch area pacing (LBBAP) is a form of conduction system pacing. Long term data on the safety and performance of LBBAP one year post device implantation has not been well described.

Methods And Results: Sixty-five patients (49% females) who received LBBAP for bradycardia indications using the SelectSecure 3830 lead (Medtronic, Minneapolis, MN) were retrospectively evaluated. Read More

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The efficacy of pacemaker implantation for extracardiac total cavopulmonary connection in a pediatric patient with bradycardia-tachycardia syndrome.

J Cardiol Cases 2022 May 22;25(5):255-258. Epub 2021 Nov 22.

Department of Pediatrics, Toyama Prefectural Central Hospital, 2-2-78 Nishinagae-cho, Toyama-shi, Toyama, 930-8550, Japan.

A 9-year-old boy, diagnosed with double outlet right ventricle after birth, suffered sinus node dysfunction and non-sustained junctional tachycardia after an extracardiac total cavopulmonary connection (TCPC). Spontaneous atrial tachycardia appeared 3 years after an extracardiac TCPC. Sotalol was administered but the bradycardia was obvious. Read More

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Prolonged sinus arrest due to the obstruction of a sinus node branch after percutaneous coronary intervention of the right coronary artery.

J Cardiol Cases 2022 May 31;25(5):319-322. Epub 2021 Dec 31.

Department of Cardiology, Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan.

Myocardial ischemia due to narrowing of the right coronary artery (RCA) may result in sinus arrhythmias, which usually present as transient sinus bradycardia with no hemodynamic instability. We report a rare case of sinus arrest with hemodynamic instability, which lasted for several months, and was caused by the occlusion of the sinus node (SN) artery following the RCA stenting. A 78-year-old woman with diabetes mellitus, hypertension, and dyslipidemia was referred to our hospital because of chest pain during activity. Read More

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A community-based study on electrocardiographic abnormalities of adult population from South India - Findings from a cross sectional survey.

Indian Heart J 2022 May 13. Epub 2022 May 13.

Achutha Menon Centre for Health Science Studies, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum Medical College, P.O., Thiruvananthapuram, Kerala, India. Electronic address:

Background: There are no data on electrocardiographic (ECG) findings from general population of Indian subcontinent. We analyzed ECG abnormalities of in adults as part of a community survey of prevalence of coronary artery disease and risk factors from South India.

Methods And Results: In this cross-sectional study of men and women between the ages 20 to 79 years, ECGs recorded digitally were analyzed using the Minnesota code. Read More

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ECG Utilization Patterns of Patients With Arrhythmias During COVID-19 Epidemic and Post-SARS-CoV-2 Eras in Shanghai, China.

Front Cardiovasc Med 2022 27;9:829679. Epub 2022 Apr 27.

Department of Cardiology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Background: The COVID-19 pandemic has led to concerns around its subsequent impact on global health.

Objective: To investigate the health-seeking behavior, reflected by ECG utilization patterns, of patients with non-COVID-19 diseases during and after COVID-19 epidemic.

Methods: Taking advantage of the remote ECG system covering 278 medical institutions throughout Shanghai, the numbers of medical visits with ECG examinations during the lockdown (between January 23 and April 7, 2020), post-lockdown (between April 8 and December 31, 2020) and post-SARS-CoV-2 (between January 23 and April 7, 2021) periods were analyzed and compared against those during the same periods of the preceding years (2018 and 2019). Read More

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Recurrent Syncope in a Case with Mediastinal Lymphoma.

Int Heart J 2022 May 14. Epub 2022 May 14.

Department of Cardiovascular Medicine, Kumamoto University School of Medicine.

An 83-year-old man suddenly lost consciousness, and his blood pressure dropped. Results of blood analysis were within normal range. A chest radiograph showed enlargement of the left mediastinum. Read More

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Comparison of heart rate after phenylephrine versus norepinephrine initiation in patients with septic shock and atrial fibrillation.

Chest 2022 May 5. Epub 2022 May 5.

Section of Pulmonary, Allergy, Sleep, and Critical Care Medicine, Department of Medicine, Boston University School of Medicine, Boston, MA 02118.

Background: Atrial fibrillation (AF) is a common complication of sepsis. It is unclear if norepinephrine, an α- and β-agonist, and phenylephrine, an α-agonist, are associated with different heart rates among patients with sepsis and AF.

Research Question: Among patients with sepsis and AF, what is the difference in heart rate after phenylephrine initiation versus norepinephrine initiation?

Study Design And Methods: Using the Medical Information Mart in Intensive Care (MIMIC)-IV database, we identified patients with sepsis and AF at the time norepinephrine or phenylephrine initiation. Read More

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Sinus Arrest in Asymptomatic COVID-19 Infection.

Cureus 2022 Apr 1;14(4):e23736. Epub 2022 Apr 1.

Department of Emergency Medicine, Henry Ford Health, Wyandotte, USA.

Coronavirus disease 2019 (COVID-19) is a viral respiratory tract syndrome capable of affecting a multitude of major organs in the human body. It is a known cause of severe vascular compromise, myocardial ischemia, myocarditis, and various cardiac dysrhythmias. Dysfunction of the sinoatrial (SA) node, the primary pacemaker of the heart, can arise from structural heart disease, medications, electrolyte abnormalities, and hypothyroidism. Read More

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Utility of magnesium sulfate in the treatment of rapid atrial fibrillation in the emergency department: a systematic review and meta-analysis.

Eur J Emerg Med 2022 May 2. Epub 2022 May 2.

Department of Emergency Medicine, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia.

Atrial fibrillation with rapid ventricular response (Afib/RVR) is a frequent reason for emergency department (ED) visits and can be treated with a variety of pharmacological agents. Magnesium sulfate has been used to prevent and treat postoperative Afib/RVR. We performed a systematic review and meta-analysis to assess the effectiveness of magnesium for treatment of Afib/RVR in the ED. Read More

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A Rare Presentation of Sick Sinus Syndrome: Generalized Seizures.

Cureus 2022 Mar 29;14(3):e23631. Epub 2022 Mar 29.

Cardiology, Trinitas Regional Medical Center, Elizabeth, USA.

Cardiac and neurological disorders are the main broad etiologies for loss of consciousness. Ictal bradycardia syndrome refers to epileptic discharges that profoundly disrupt normal cardiac rhythm, resulting in cardiogenic syncope during the ictal event. Convulsive syncope is a well-described phenomenon in both adults and children in which abrupt cerebral hypoperfusion leads to brief extensor stiffening and non-sustained myoclonus. Read More

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Cardiac complications of COVID-19: Incidence and outcomes.

Indian Heart J 2022 Apr 29. Epub 2022 Apr 29.

Division of Cardiology, University of Texas Health San Antonio, USA.

Background: Coronavirus disease-2019 (COVID-19) has been associated with pre-existing cardiac conditions as well as cardiovascular complications. The incidence rates of cardiac complications, age, and gender differences in this population are unknown.

Objectives: We wanted to study the incidence of cardiac complications and mortality in patients with COVID-19. Read More

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Neurogenic stunned myocardium resulting from surgical brainstem handling during resection of paediatric recurrent medulloblastoma-a possible brain heart interaction.

Childs Nerv Syst 2022 Apr 23. Epub 2022 Apr 23.

Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.

Background: Neurogenic stunned myocardium (NSM) is characterised by an acute onset cardiac dysfunction following an acute neurological insult which mimics acute coronary syndrome.

Case Details: A 12-year-old male child was admitted to the neuro-intensive care unit (NICU) following midline suboccipital craniotomy and resection of recurrent medulloblastoma. Postoperatively, in NICU, he developed tachycardia and hypotension, which was unresponsive to fluid challenge requiring norepinephrine infusion. Read More

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Programming Optimization in Implantable Cardiac Monitors to Reduce False-Positive Arrhythmia Alerts: A Call for Research.

Diagnostics (Basel) 2022 Apr 15;12(4). Epub 2022 Apr 15.

Department of Cardiology, S. Chiara Hospital, 38122 Trento, Italy.

No studies have investigated whether optimizing implantable cardiac monitors (ICM) programming can reduce false-positive (FP) alerts. We identified patients implanted with an ICM (BIOMONITOR III) who had more than 10 FP alerts in a 1-month retrospective period. Uniform adjustments of settings were performed based on the mechanism of FP triggers and assessed at 1 month. Read More

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A phase I randomized, double-blind, single subcutaneous dose escalation study to determine the safety, tolerability, and pharmacokinetics of rezafungin in healthy adult subjects.

Clin Transl Sci 2022 Apr 19. Epub 2022 Apr 19.

Cidara Therapeutics, San Diego, California, USA.

Rezafungin is a novel echinocandin being developed for the treatment and prevention of invasive fungal infections. The objectives of this randomized, double-blind study in healthy adults were to determine the safety, tolerability, and pharmacokinetics of rezafungin after subcutaneous (s.c. Read More

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Assessing cardiac safety among clients receiving methadone as part of opioid agonist maintenance therapy (OAMT) in Durban, South Africa.

J Addict Dis 2022 Apr 19:1-9. Epub 2022 Apr 19.

Department of Cardiology, University of KwaZulu-Natal, Durban, South Africa.

Methadone is a recommended medication for opioid agonist maintenance therapy (OAMT). However, methadone can have cardiac side effects. There is limited South African cardiac safety data on methadone. Read More

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Bradycardia in a Patient with Severe COVID-19.

Isr Med Assoc J 2022 Apr;24(4):212-214

Internal Medicine B, Sheba Medical Center, Tel Hashomer, Israel.

Background: Heart rate disorders and in particular sinus arrhythmias are known to accompany viral infections. Sinus tachycardia is prevalent in the presence of increased body temperature and respiratory rate. However, bradycardia has also been described for centuries to complicate viral illnesses. Read More

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Treatment of sick sinus syndrome in a patient with cardiac lymphoma via chemotherapy without pacemaker implantation: A case report.

Clin Case Rep 2022 Apr 4;10(4):e05649. Epub 2022 Apr 4.

Department of Hematology and Oncology Kita-Harima Medical Center Hyogo Japan.

Successful treatment of the acute phase of bradycardia in patients with cardiac lymphoma via medical therapy alone has not been reported. This case report describes the successful treatment of sick sinus syndrome in an 84-year-old man with cardiac lymphoma via chemotherapy without pacemaker implantation. Read More

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Swallow Syncope Associated With Intermittent Sinus Pause and High-Degree Atrioventricular Block: A Case Report.

Cureus 2022 Mar 7;14(3):e22915. Epub 2022 Mar 7.

Interventional Radiology, Louisiana State University Health Sciences Center, Shreveport, USA.

Swallow syncope, also known as deglutition syncope, is a relatively rare neurogenic disorder that is triggered by oral intake. When diagnosed, swallow syncope is treatable, but it is challenging to identify without proper history and prior knowledge of this disorder. Here, we describe the case of a 68-year-old female with a complex history who presented to the emergency room with complaints of worsening long-term intermittent lightheadedness and dizziness associated with swallowing. Read More

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Serious Cardiac Arrhythmias Detected by Subcutaneous Long-term Cardiac Monitors in Patients With Drug-Resistant Epilepsy.

Neurology 2022 05 6;98(19):e1923-e1932. Epub 2022 Apr 6.

From the Department of Neuroscience, Central Clinical School (S.S., Z.L., P.C.-E., N.C.J., M.T., C.F., J.-P.N., P.P., P.K., T.J.O.), Monash University; Department of Neurology (S.S., P.C.-E., N.C.J., M.T., J.-P.N., P.P., P.K., T.J.O.), The Alfred Hospital, Melbourne; Department of Medicine (S.S., P.C.-E., N.C.J., M.T., V.C., R.Y., C.F., J.-P.N., P.K., T.J.O.), The Royal Melbourne Hospital, The University of Melbourne; Departments of Neurology (S.S., F.S., M.T., V.C., R.Y., C.F., J.-P.N., P.P., P.K., T.J.O.) and Cardiology (F.S., P.S.), The Royal Melbourne Hospital, Parkville; Department of Neurology (E.M., U.S.), Monash Medical Centre, Clayton, Australia; Academic Neurology Unit (V.C.), Royal Hallamshire Hospital, University of Sheffield, Division of Neuroscience and Experimental Psychology (V.C.), School of Biological Sciences, University of Manchester, UK; Department of Medicine (P.P.), Austin Hospital, The University of Melbourne; and Bladin-Berkovic Comprehensive Epilepsy Program (P.P.), Austin Health, Heidelberg, Australia.

Background And Objectives: Epilepsy is associated with an increased risk of cardiovascular disease and premature mortality, including sudden unexpected death in epilepsy (SUDEP). Serious cardiac arrythmias might go undetected in routine epilepsy and cardiac investigations.

Methods: This prospective cohort study aimed to detect cardiac arrhythmias in patients with chronic drug-resistant epilepsy (≥5 years duration) using subcutaneous cardiac monitors for a minimum follow-up duration of 12 months. Read More

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Fluphenazine decanoate-induced bradycardia: A case report.

Neuropsychopharmacol Rep 2022 Apr 3. Epub 2022 Apr 3.

Department of Psychiatry, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

Sinus tachycardia and orthostatic hypotension have been so far reported among the negative cardiovascular complications of antipsychotic agents. This study aimed to report a case with bradycardia induced by fluphenazine decanoate administration. The patient was a 29-year-old man, admitted to the general teaching hospital in Sari, Iran, with a complaint of abdominal and gastric pain as well as weight loss following 7 months of fasting based on religious delusions. Read More

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Pacemaker Implantation in Juvenile Neuronal Ceroid Lipofuscinosis (CLN3)-A Long-Term Follow-Up Study.

Front Neurol 2022 10;13:846240. Epub 2022 Mar 10.

Department of Pediatrics and Adolescent Medicine, Centre for Rare Diseases, Aarhus University Hospital, Aarhus, Denmark.

It is well documented that deteriorating heart function due to deposition of ceroid lipopigment is a significant co-morbidity in Juvenile Neuronal Ceroid Lipofuscinosis (CLN3 disease) although the exact disease mechanisms remain unknown in any NCL form. An increasing frequency of cardiac conduction disorders including severe bradycardia and sinus arrest is seen in the late teens, as is a left ventricular hypertrophy in the early 20s. Only a few case reports of pacemaker implantation have been published, and so far, no long-term follow-up study exists. Read More

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A Case Report of Flecainide Toxicity With Review of Literature.

Cureus 2022 Feb 15;14(2):e22261. Epub 2022 Feb 15.

Department of Cardiology, Memorial Healthcare System, Hollywood, USA.

Flecainide is an anti-arrhythmic drug with a narrow therapeutic index. Flecainide toxicity is rare, but the mortality is high. This case demonstrates the use of intravenous fat emulsion therapy in conjunction with intravenous sodium bicarbonate treatment for flecainide toxicity. Read More

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February 2022

Cardioneuroablation for the treatment of vasovagal syncope and sinus bradycardia with atrial escape.

J Interv Card Electrophysiol 2022 Mar 29. Epub 2022 Mar 29.

Department of Cardiology, Rush Medical College, Chicago, IL, USA.

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[The Pacemaker and Implantable Cardioverter-Defibrillator Registry of the Italian Association of Arrhythmology and Cardiac Pacing - Report 2020].

G Ital Cardiol (Rome) 2022 Apr;23(4):309-313

Clinica di Cardiologia, Università dell'Insubria, Ospedale di Circolo, Varese.

Background: The Pacemaker (PM) and Implantable Cardioverter-Defibrillator (ICD) Registry of the Italian Association of Arrhythmology and Cardiac Pacing (AIAC) collects information about demographics, clinical characteristics, main indications for PM/ICD therapy and device types from the Italian collaborating centers.

Methods: For the year 2020, the main data about national PM and ICD implantation activity were obtained on the basis of European Cards and subsequently analyzed to create a standard report.

Results: PM Registry: data about 22 080 PM implantations were collected (18 027 first implants and 3803 replacements). Read More

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Clinical Presentation of Left Ventricular Noncompaction Cardiomyopathy and Bradycardia in Three Families Carrying Pathogenic Variants.

Genes (Basel) 2022 03 8;13(3). Epub 2022 Mar 8.

Department of Cardiology, The Children's Memorial Health Institute, 04-730 Warsaw, Poland.

Background: Left ventricular noncompaction (LVNC) is a genetically and phenotypically heterogeneous cardiomyopathy in which myocardium consists of two, distinct compacted and noncompacted layers, and prominent ventricular trabeculations and deep intertrabecular recesses are present. LVNC is associated with an increased risk of heart failure, atrial and ventricular arrhythmias and thromboembolic events. Familial forms of primary sinus bradycardia have been attributed to alterations in . Read More

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Severe pre-operative sinus bradycardia improved by mediastinal lymph node dissection.

BMC Surg 2022 Mar 22;22(1):107. Epub 2022 Mar 22.

Department of Anesthesiology, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital & Institute, Beijing, 100142, China.

Background: We report a case of bradycardia improved by surgical resection of the paratracheal lymph nodes, which has rarely been reported in the literature.

Case Presentation: A 41-year-old male patient with pre-operative sinus bradycardia was diagnosed with right upper lobe adenocarcinoma. He planned to undergo VATS right upper lobectomy and mediastinal lymph node dissection. Read More

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Severe bradycardia in a teenager as the initial manifestation for Guillain Barré syndrome: a case report.

BMC Pediatr 2022 03 22;22(1):152. Epub 2022 Mar 22.

Pediatric Intensive Care Unit, Fundación Cardioinfantil IC University Hospital. Pediatric Intensive Care Fellowship Program, La Sabana University, Bogotá, Colombia.

Background: Guillain-Barré syndrome is the most common cause of flaccid paralysis, with multiple known clinical variants. Autonomic dysfunction, although frequently reported in the clinical course, is often overlooked in the pediatric population and is usually not the initial presenting symptom in this age group CASE PRESENTATION: We present the case of a previously healthy 17-year-old who arrived at the Emergency Department complaining of gastrointestinal symptoms associated with lipothymia. An initial electrocardiogram (ECG) showed sustained sinus bradycardia subsequently associated with arterial hypertension. Read More

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Remdesivir-Associated Sinus Arrest in COVID-19: A Potential Indication for Close Cardiac Monitoring.

Cureus 2022 Feb 17;14(2):e22328. Epub 2022 Feb 17.

Internal Medicine, Southeast Health Medical Center, Dothan, USA.

Remdesivir is an antiviral, nucleoside analog used extensively during the coronavirus-disease 2019 (COVID-19) pandemic with proven efficacy against COVID-19-induced acute respiratory distress syndrome (ARDS). Our case report details the clinical course of a 50-year-old, COVID-19-positive patient who developed sinus arrest after being treated with remdesivir. Within 24 hours of discontinuing remdesivir therapy, the patient's sinus arrest resolved to a normal sinus rhythm. Read More

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February 2022