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Physiol Behav 2018 Dec 3. Epub 2018 Dec 3.

Institute for Drug and Alcohol Studies, Departments of Psychiatry, Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA 23298, United States.

Psychopathy is one of the most researched risk factors for violence. Yet, research in women is sparse. The present study aimed to test if the link between the four-facet structure of psychopathy and interpersonal violence and aggression was moderated by neurobiological function (indexed by resting respiratory sinus arrhythmia; RSA). Read More

Int J Oral Maxillofac Implants 2018 Dec 5. Epub 2018 Dec 5.

Purpose: Scientific publications have recently found that bone graft quality and implant survival rates were not influenced by antrostomy membrane coverage during maxillary sinus floor augmentation with a lateral approach. The aim of this study was to evaluate the stability of the bone substitute after a maxillary sinus floor augmentation procedure with or without using a covering membrane.

Materials And Methods: This retrospective study evaluated all patients who were enrolled between April 2016 and January 2017. Read More

Int J Oral Maxillofac Implants 2018 Dec 5. Epub 2018 Dec 5.

Purpose: The purpose of this study was to evaluate a new graft material, biphasic calcium phosphate, composed of 60% hydroxyapatite and 40% β-Tricalcium phosphate and deproteinized bovine bone mineral, which is established as a predictable graft material for maxillary sinus augmentation.

Materials And Methods: Maxillary sinus augmentation was performed with different bone materials. Bone biopsies were performed on tissue harvested from the future implant bed using a trephine bur at 6 months after maxillary sinus augmentation. Read More

Int J Oral Maxillofac Implants 2018 Dec 5. Epub 2018 Dec 5.

Purpose: To evaluate the influence of the height of the antrostomy on dimensional variations of the elevated space after sinus floor elevation.

Materials And Methods: Twenty-four healthy volunteers planned for sinus floor elevation were included in the study. An antrostomy of either 4 mm (Group A) or 8 mm (Group B) in height was prepared in the lateral wall of the sinus. Read More

Folia Med Cracov 2018 ;58(3):67-81

Department of Radiology, Jagiellonian University Medical College, Kraków, Poland.

Purpose: The purpose of this research is to define the total number of septa and the total number of antra in the sphenoid sinuses (created as a result of the presence of additional septa), as well as the relation between the number of the septa and their location in the adult population.

Materials And Methods: e study was conducted as a retrospective analysis of the computed tomography (CT) scans of the paranasal sinuses of 296 patients (147 females and 149 males), who did not present any pathology in the sphenoid sinuses. The CT scans of the paranasal sinuses were done with the spiral CT scanner (Siemens Somatom Sensation 16) by using a standard procedure, in the option Siemens CARE Dose 4D, without using any contrast medium. Read More

G Ital Cardiol (Rome) 2018 Dec;19(12):705-713

Divisione di Cardiologia Interventistica, Dipartimento Cardio-Toraco-Vascolare, Istituto Scientifico San Raffaele, Milano.

Refractory angina is a disabling condition that afflicts patients in whom we have no more strategy to improve their quality of life. This phenomenon has been increasing over the last years due to longer life expectancy, also resulting in a significant impact upon healthcare resources. The coronary sinus Reducer is a novel technology designed to improve the quality of life of these patients. Read More

Saudi Med J 2018 Dec;39(12):1238-1241

Department of Otolaryngology-Head and Neck Surgery, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia. E-mail.

Objectives: To determine the mean nasal skin thickness in the Middle Eastern population and to assess the effect of skin thickness on patients' satisfaction following rhinoplasty surgeries. Methods: Radiological measurements of skin thickness at the 3 vertical thirds of the nasal dorsum were taken. A total of 154 patients (80 females and 74 males) who were scheduled for computed tomography scan for the paranasal sinuses were included in the study. Read More

Anatol J Cardiol 2018 Dec 6. Epub 2018 Dec 6.

Department of Cardiology, The First Affiliated Hospital, China Medical University; Shenyang-China.

Objective: The relationship between prognosis and heart rate remains unclear among patients diagnosed with heart failure with mid-range ejection fraction (HFmrEF). The aim of the present study was to assess the effect of heart rate in this group of patients.

Methods: Of the 197 patients diagnosed with HFmrEF, 92 had a heart rate <70 beats/min (bpm), and 105 had a heart rate ≥70 bpm. Read More

Circ Arrhythm Electrophysiol 2018 Nov;11(11):e006720

Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands (E.M.J.P.M., L.J.M.E.v.d.D., E.A.H.L., C.P.T., P.K., N.M.S.d.G.).

Background: Extensiveness of conduction delay and block at the pulmonary vein area (PVA) was quantified in a previous study. We hypothesized that the combination of lines of conduction block with multiple concomitantly entering sinus rhythm wavefronts at the PVA may result in increased arrhythmogenicity and susceptibility to atrial fibrillation (AF).

Methods: Intraoperative high-density epicardial mapping of PVA (N≈450 sites, interelectrode distances: 2 mm) was performed during sinus rhythm in 327 patients (241 male [74%], 67±10 [21-84] years) with and without preoperative AF. Read More

Laryngoscope 2018 Dec 5. Epub 2018 Dec 5.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania.

Objectives/hypothesis: Currently, due to the rarity of pathology, there are limited data surrounding outcomes of pediatric skull base surgery. Traditionally, surgeons have proceeded with caution when electing endonasal endoscopic transsellar/transplanum approaches to the skull base in pediatric patients due to poor sphenoid pneumatization. In this study, we review outcomes of endoscopic pediatric skull base surgery based on sphenoid pneumatization patterns. Read More

Biomed Res Int 2018 4;2018:9352130. Epub 2018 Nov 4.

Department of Medical, Surgical and Health Sciences, University of Trieste, Italy.

Aim: To evaluate, with three-dimensional analysis, the effectiveness of alveolar ridge preservation (ARP) after maxillary molar extraction in reducing alveolar bone resorption and maxillary sinus pneumatization when compared to unassisted socket healing.

Methods: Patients were included in the study following inclusion criteria and underwent minimally traumatic maxillary molar extraction followed by ARP using synthetic nanohydroxyapatite (Fisiograft Bone, Ghimas, Italy) (test group) or unassisted socket healing (control group). Cone-beam computerized tomographies (CBCT) were performed immediately after tooth extraction (T0) and 6 months postoperatively (T1). Read More

J Clin Aesthet Dermatol 2018 Oct 1;11(10):17-23. Epub 2018 Oct 1.

Drs. Vinkel and Thomsen are with the Department of Dermatology at Bispebjerg Hospital in Copenhagen, Denmark.

Hidradenitis suppurativa (HS), a relatively common and chronic inflammatory skin disorder. HS can have debilitating consequences if not diagnosed and treated appropriately. Clinically defined by recurrent, inflamed nodules in intertriginous regions (i. Read More

Clin Cosmet Investig Dent 2018 8;10:245-249. Epub 2018 Nov 8.

Department of Oral Implantology, CA Implantes, São Paulo, Brazil.

An oroantral fistula is a complication of the maxillary posterior teeth that can occur after a tooth extraction that affects the maxillary sinus. Improper management may lead to a persistent fistula, which may become chronic. In this case report, platelet-rich fibrin (PRF) was used with a collagen membrane to close a chronic fistula in a single patient. Read More

Int Heart J 2018 Dec 5. Epub 2018 Dec 5.

Department of Cardiology, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University.

The mechanism underlying thrombosis in atrial fibrillation (AF) is not yet clearly understood. The apelin/APJ axis parallel and counter-regulate with the angiotensin system. The present study hypothesizes that apelin/APJ axis exert its anti-thrombus effect in normal left atrial tissue and is disrupted by up-regulated renin-angiotensin-aldosterone system (RAAS) signaling during AF. Read More

Int Heart J 2018 Dec 5. Epub 2018 Dec 5.

Department of Cardiology, Atrial Fibrillation Center, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences.

The incidence of atrial tachycardia (AT) after rheumatic mitral valvular (RMV) surgery has been well described. However, there have been few reports on the characteristics, mechanism, and long-term ablation outcome of ATs after RMV surgery and concomitant Cox-MAZE IV procedure.The present study reviewed consecutive patients who underwent AT ablation between May 2008 and July 2013. Read More

Actas Urol Esp 2018 Dec 6;42(10):645-648. Epub 2018 Jul 6.

Servicio de Urología, Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Madrid, España.

Objective: To recall the history of the discovery of non-nephron cystic disease, detected simultaneously in 2 hospitals in Madrid, and the vicissitudes that the authors endured during the process of recognising this disease, while being ignored by the international scientific literature.

Material And Method: We analysed the authors' first publications and presentations, their correspondence relaying the difficulties in reporting the confusion with adult polycystic kidney disease (APKD) and the subsequent nosological identification of the process. We consulted with individuals who worked with the 2 authors to increase the accuracy and objectivity of the history report. Read More

Indian Pacing Electrophysiol J 2018 Nov 30. Epub 2018 Nov 30.

Department of Pediatric Cardiology, Madras Medical Mission, Chennai, India. Electronic address:

Fontan surgery and its modifications have improved survival in various forms of univentricular hearts. A regular atrial rhythm with atrioventricular synchrony is one of the most important prerequisite for the long-term effective functioning of this preload dependent circulation. A significant proportion of these survivors need various forms of pacing for bradyarrhythmias, often due to sinus nodal dysfunction and sometimes due to atrioventricular nodal block. Read More

Biochim Biophys Acta Gen Subj 2018 Nov 30. Epub 2018 Nov 30.

A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70210 Kuopio, Finland; Gene Therapy Unit, Kuopio University Hospital, Kuopio, 70211 Kuopio, Finland; Heart Center, Kuopio University Hospital, 70211 Kuopio, Finland. Electronic address:

Statins are effective drugs used to prevent and treat cardiovascular diseases but their effects in the absence of low density lipoprotein receptor (LDLR) and on the risk of diabetes are not yet well characterized. The aim of this study was to clarify systemic and pleiotropic effects of rosuvastatin on cardiovascular and diabetic phenotypes. IGF-II/LDLRApoB hypercholesterolemic prediabetic mice were used to test the effects of rosuvastatin on plasma glucose, insulin, lipids, atherosclerosis and liver steatosis. Read More

Int Forum Allergy Rhinol 2018 Dec 3. Epub 2018 Dec 3.

Department of Otolaryngology-Head and Neck Surgery, Department of Anesthesiology, New York-Presbyterian Hospital-Weill Cornell Medicine, New York, NY.

Background: Opioid-based analgesics are routinely prescribed after elective rhinologic surgery. Balancing appropriate pain management while avoiding overprescription necessitates an evidence-based approach.

Methods: Patients undergoing elective rhinologic surgery, including endoscopic sinus surgery (ESS), septoplasty, or ESS with septoplasty, were prospectively enrolled. Read More

Interact Cardiovasc Thorac Surg 2018 Dec 1. Epub 2018 Dec 1.

Department of Thoracic and Cardiovascular Surgery, Research Institute of Clinical Medicine, Chonbuk National University Hospital, Chonbuk National University Medical School, Jeonju, Republic of Korea.

The isolated coronary sinus (CS) rupture causing cardiac tamponade following blunt chest trauma is a very rare and very unique traumatic form of cardiac tamponade. Prompt recognition of this injury is crucial for patient survival. CS injuries are frequently difficult to repair and are potentially lethal. Read More

Europace 2018 Nov 30. Epub 2018 Nov 30.

Arrhythmologic Center, Ospedali del Tigullio, Via Don Bobbio 24, 16033 Lavagna, Italy.

Aims: Anatomical placement of the coronary sinus (CS) lead in basal or mid-ventricular positions of the posterior and lateral walls is associated with a better clinical outcome of cardiac resynchronization therapy (CRT). We hypothesized that optimization of CS lead placement targeted the right-to-left electrical delay (RLD) predicts an additional clinical benefit.

Methods And Results: The CS lead was placed according to current standards in 90 patients (Conventional group) and at the site of the longest RLD in 121 patients (RLD group). Read More

Medwave 2018 Nov 23;18(7):e7347. Epub 2018 Nov 23.

Proyecto Epistemonikos, Santiago, Chile; Departamento de Otorrinolaringología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile. Email: Address: Centro Evidencia UC, Pontificia Universidad Católica de Chile, Diagonal Paraguay 476, Santiago, Chile.

Introduction: Chronic rhinosinusitis is a high prevalence chronic inflammatory disease that involves nasal mucosa and paranasal sinuses. Immunoglobulin E is an inflammatory mediator that plays an etiopathogenic role in this condition, so omalizumab, an anti-immunoglobulin E monoclonal antibody, might be a therapeutic alternative.

Methods: We searched in Epistemonikos, the largest database of systematic reviews in health, which is maintained by screening multiple information sources, including MEDLINE, EMBASE, Cochrane, among others. Read More

J Craniofac Surg 2018 Nov 30. Epub 2018 Nov 30.

Department of Plastic and Reconstructive Surgery, Johns Hopkins Hospital, Baltimore, MD.

Background: While autologous split calvarial bone is an ideal graft material in cranioplasty, selection of a donor site can be challenging and limited in the reconstruction of complicated cranial defects. Computer-aided design and manufacturing (CAD/CAM) may improve donor-site harvest and contouring and mitigate operative complications in split calvarial bone graft-based cranioplasty for complex patients, but has not previously been studied in this unique setting.

Methods: In this study, a retrospective review of patients who presented to the institution and underwent split-calvarial bone graft-based cranioplasty using CAD/CAM to optimize reconstruction of full-thickness cranial defects ≥30 cm was performed. Read More

J Craniofac Surg 2018 Nov 30. Epub 2018 Nov 30.

Department of Oculoplastic, Orbital and Lacrimal Surgery, Aichi Medical University Hospital.

A study on immunoglobulin G4-related ophthalmic disease (IgG4-ROD) with destructive changes in periorbital soft tissues was presented. The patient was an 89-year-old-man who developed a left-sided orbital lesion involving the globe, lacrimal gland, and extraocular muscles. A diagnosis of definite IgG4-ROD was made based on clinical and histopathologic findings. Read More

Curr Opin Otolaryngol Head Neck Surg 2018 Nov 16. Epub 2018 Nov 16.

Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Purpose Of Review: Sphenoid sinus lateral recess encephalocoeles (SSLRE) are rare occurrences and pose unique challenges due to limited surgical access for endoscopic endonasal repair and also the lack of consensus on optimal perioperative managements specifically in the spontaneous cases, which are also believed to be a variant of idiopathic intracranial hypertension (IIH). Endoscopic endonasal approaches have largely replaced the transcranial route and the techniques are continuously being refined to reduce the neurovascular morbidity and improve outcome.

Recent Findings: Transpetrygoid is the most utilized approach with modifications suggested to limit bone removal, exposure and preservation of the neurovascular structures as dictated by the extent of the lateral recess. Read More

Curr Opin Otolaryngol Head Neck Surg 2018 Nov 30. Epub 2018 Nov 30.

Rhinology & Endoscopic Skull Base Surgery, UCLA Department of Head & Neck Surgery, Los Angeles, California, USA.

Purpose Of Review: The purpose of the review is to evaluate the current indications and contraindications for balloon sinuplasty and review the clinical trials performed in this area.

Recent Findings: The indications for balloon sinus dilatation are somewhat similar to those for endoscopic sinus surgery. Balloon sinus ostial dilation (BSD) has been found to be most effective in the treatment of recurrent acute sinusitis (RARS) and chronic rhinosinusitis without nasal polyposis (CRSsNP) that has been refractory to medical therapy. Read More

Implant Dent 2018 Nov 30. Epub 2018 Nov 30.

Professor, Division of Clinical Medicine, Department of Oral and Maxillofacial Surgery, Graduate Faculty of Interdisciplinary, University of Yamanashi, Yamanashi, Japan.

Purpose: We investigated whether it was possible to perform a sinus lift maintaining absorbable screw material with biological activity.

Materials And Methods: Thirty rabbits were used. The screws used in this study were unsintered hydroxyapatite/poly-L-lactic acid (uHA/PLLA) (uHA/PLLA group) and titanium alloy (Ti group). Read More

IEEE J Biomed Health Inform 2018 Dec 3. Epub 2018 Dec 3.

Objective: This paper proposes an approach to better estimate the sympathovagal balance (SB) and the respiratory sinus arrhythmia (RSA) after separating respiratory influences from the heart rate (HR).

Methods: The separation is performed using orthogonal subspace projections and the approach is first tested using simulated HR and respiratory signals with different spectral properties. Then, RSA and SB are estimated during autonomic blockade and stress using the proposed approach and the classical heart rate variability (HRV) analysis. Read More

Acta Cardiol 2018 Dec 3:1-7. Epub 2018 Dec 3.

a Dipartimento di Medicina Interna e Scienze Biomediche, Sezione di Cardiologia , Università degli Studi di Parma , Parma , Italy.

Background: We aimed to depict the electrocardiographic and echocardiographic aspects in patients before elective major vascular surgery.

Methods: We evaluated through standard 12 lead electrocardiography and transthoracic echocardiography 469 patients with asymptomatic large abdominal aortic aneurysm (AAA), 334 with critical carotid stenosis (CAS), and 238 with advanced peripheral artery disease (PAD) before surgical revascularization.

Results: Patients with AAA were predominantly males (p < . Read More

Dev Psychol 2018 Dec 3. Epub 2018 Dec 3.

Youth Development Institute, Department of Human Development and Family Science, The University of Georgia.

Physiological synchrony, or concordance, among caregiver-child dyads involves the matching of biological states. Understanding this process is critical for enhancing our knowledge of the ways that the caregiver-child relationship supports child development. However, the meaning of physiological synchrony for child adjustment is poorly understood. Read More

Echocardiography 2018 Dec 1. Epub 2018 Dec 1.

Icahn School of Medicine at Mount Sinai, New York, New York.

A number of masses and pseudomasses may be encountered during the echocardiographic examination of the transverse and oblique sinuses with significant clinical implications. This review discusses the clinically relevant anatomy of the pericardial sinuses emphasizing diagnostic pitfalls that may be encountered during their echocardiographic examination. Read More

Zhonghua Wei Chang Wai Ke Za Zhi 2018 Nov;21(11):1291-1295

Department of Gastrointestinal Surgery, Provincial Clinical College, Fujian Medical University, Fuzhou 350001, China.

Objective: To investigate the safety of the controllable ileostomy with pipe in view of histology.

Methods: Twenty-eight Beagle dogs undergoing controllable ileostomy with pipe were studied. The special fistula tube with balloon was placed into the hole locating at the cecal root opposing the mesenteric side, and fixed by double knot compression method. Read More

Pituitary 2018 Nov 30. Epub 2018 Nov 30.

Department of Neurosurgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei, China.

Purpose: This paper examines the application of 3D printing technology in the endoscopic endonasal approach for the treatment of macroadenomas.

Methods: We have retrospectively analysed 20 patients who diagnosed with macroadenoma underwent endoscopic transsphenoidal surgery in Wuhan Union hospital from January 2017 to May 2017. Among the 20 patients, 10 patients received the service of 3D printing technology preoperatively. Read More

J Interv Card Electrophysiol 2018 Dec 1. Epub 2018 Dec 1.

Cardiology Department, NIMTS Hospital, Athens, Greece.

Background/objective: Radiofrequency catheter ablation (RFCA) of focal atrial tachycardia (FAT) traditionally is guided by conventional endocardial mapping of earliest atrial activation; however, more recently electro-anatomical mapping is heralded as a more effective, albeit more expensive, tool to guide ablation. Herein we present the results of conventional mapping-guided RFCA. Apropos, we conducted a literature search of studies reporting > 10 FAT patients submitted to RFCA. Read More

Neurol Sci 2018 Dec 1. Epub 2018 Dec 1.

Unit of Medical Humanities, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua Medical School, via A. Gabelli 61, 35121, Padua, Italy.

The third sentence from the beginning in our article. Read More

Ophthalmologe 2018 Nov 30. Epub 2018 Nov 30.

Klinik und Poliklinik für Augenheilkunde, Klinikum der Universität Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Deutschland.

Background: Glaucoma due to elevated episcleral venous pressure is a rare and difficult to treat form of secondary open angle glaucoma.

Objective: The pathophysiology, clinical findings, differential diagnosis and treatment options are discussed. Radius-Maumenee syndrome, Sturge-Weber syndrome and carotid-cavernous sinus fistulas are covered in particular. Read More

Indian Dermatol Online J 2018 Nov-Dec;9(6):441-444

Department of Dental Surgery, North DMC Medical College and Hindu Rao Hospital, Malkaganj, New Delhi, India.

Cutaneous odontogenic fistulae or sinus tracts are commonly misdiagnosed and incorrectly treated, leading to unnecessary and excessive medications attributing to patient agony. An understanding of cutaneous sinus tracts and their drainage will guide to more appropriate treatment. The following clinical case reports present three patients with cutaneous sinus tracts on chin and jaw line, secondary to chronic periapical dental infection, which was misdiagnosed initially as dermatological lesion and was submitted to inappropriate dermatological treatment and antimicrobial therapy. Read More

Turk J Anaesthesiol Reanim 2018 Dec 6;46(6):424-433. Epub 2018 Sep 6.

Department of Otorhinolaryngology, Recep Tayyip Erdoğan University School of Medicine, Rize, Turkey.

Objective: Controlled hypotension is commonly induced during functional endoscopic sinus surgery to limit mucosal bleeding. This may be detrimental to elderly patients and patients with arterial stenosis. The aim of this pilot study was to determine if a normotensive anaesthetic technique with sufficient analgesia and without profound vasodilation may reduce intraoperative bleeding and incidence of adverse haemodynamic effects associated with vasodilation and variable rate continuous infusions. Read More

J Thorac Dis 2018 Nov;10(Suppl 32):S3799-S3808

Division of Thoracic Surgery, The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada.

Atrial fibrillation (AF) is the most common sustained arrhythmia after non-cardiac thoracic surgery and is associated with a significant increase in perioperative morbidity, intensive care unit (ICU) admission, and mortality. Practical guidance is needed to assist clinicians in managing this critical issue and direct further research. Here we aim to provide a synoptic review and analysis of the literature to distil practical recommendations for prediction, prevention and management of post-operative atrial fibrillation (POAF) suitable for clinical application and further evaluation. Read More

J Atr Fibrillation 2018 Aug 31;11(2):2052. Epub 2018 Aug 31.

Division of Cardiology, Altru Health System, Grand Forks, North Dakota 58201.

We present a particularly rare case and the first ever report of a ventricular self-extraction in a 98-year old female. Our patient had a past medical history significant for severe Alzheimer's dementia, paroxysmal atrial fibrillation, and sick sinus syndrome who was admitted in clinically stable condition following the unwitnessed self-extraction the ventricular lead of her dual chamber pacemaker. This case highlights the potential risks and other clinical challenges of pacemaker and ICD placement in elderly patients and in patients with cognitive impairment. Read More

Open Dent J 2018 25;12:820-826. Epub 2018 Oct 25.

Department of Periodontology, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia.

Introduction: The presence of an atrophic maxilla creates a serious challenge in cases of implant placement, while maxillary sinus pneumatization further complicates the surgery. This pilot study was performed to investigate the validity of two techniques used to estimate the volumes of bone graft material required in cases that included lateral window sinus augmentation.

Materials And Methods: Cone beam computed tomography was used for preoperative volumetric analysis of the maxillary sinus. Read More

Front Immunol 2018 16;9:2516. Epub 2018 Nov 16.

Department of Laboratory Medicine and Pathology, Center for Transfusion Medicine and Cellular Therapies, Emory University School of Medicine, Atlanta, GA, United States.

Red blood cell (RBC) alloimmunization represents a significant immunological challenge for some patients. While a variety of immune constituents likely contribute to the initiation and orchestration of alloantibodies to RBC antigens, identification of key immune factors that initiate alloantibody formation may aid in the development of a therapeutic modality to minimize or prevent this process. To define the immune factors that may be important in driving alloimmunization to an RBC antigen, we determined the specific immune compartment and distinct cells that may initially engage transfused RBCs and facilitate subsequent alloimmunization. Read More

Oman J Ophthalmol 2018 Sep-Dec;11(3):300-302

Ophthalmic Pathology Service, Apollo Health City, Hyderabad, Telangana, India.

Isolated eyelid Rosai-Dorfman disease without orbital disease or systemic involvement is very rare and needs a high degree of suspicion. In this report, we describe a 16-year-old boy who presented with isolated eyelid Rosai-Dorfman disease involving the right upper eyelid. The lesion was treated by surgical debulking followed by intralesional steroid injection for the residual lesion. Read More

Oman J Ophthalmol 2018 Sep-Dec;11(3):297-299

Department of Orbit, Oculoplasty and Ocular Oncology, Giridhar Eye Institute, Kochi, Kerala, India.

Rosai-Dorfman Disease also called as Sinus Histiocytosis with Massive Lymphadenopathy is a rare, benign, idiopathic histiocytic proliferative disorder that occurs predominantly in children and young adults. Orbital involvement can occur in 11% of cases. Isolated lacrimal gland involvement without any local or systemic recurrence is very rare. Read More

Am J Med 2018 Nov 29. Epub 2018 Nov 29.

Division of Heart Rhythm Services, Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN. Electronic address:

Int J Infect Dis 2018 Nov 29. Epub 2018 Nov 29.

Service de Médecine Interne, CHRU de Besançon, Besançon, France. Electronic address:

Puumala orthohantavirus (PUUV) is the most prevalent of the four species of zoonotic hantaviruses found in Europe, causing nephropathia epidemica, a mild form of hemorrhagic fever with acute kidney injury that presents with elevated serum creatinine level, proteinuria and hematuria. The febrile phase of the infection begins by flu-like syndrome, visual disturbance. Laboratory results can show thrombocytopenia. Read More

J Pediatr Surg 2018 Nov 7. Epub 2018 Nov 7.

Center for Colorectal and Pelvic Reconstruction, Nationwide Children's Hospital, Columbus, OH.

Aim Of The Study: The goals of urinary reconstruction in urogenital sinus and cloacal repair include: (1) positioning of the bladder neck above the urogenital diaphragm to maximize future urinary continence, and (2) creating a visible urethra that can be catheterized if needed. A recent algorithm in cloacal reconstruction proposed a urethral length of 1.5 cm as the key determinant in deciding whether to perform a total urogenital mobilization or a urogenital separation, the hypothesis being that a 1. Read More

J Prosthet Dent 2018 Nov 30. Epub 2018 Nov 30.

Associate Professor, Section of Oral Oncology and Maxillofacial Prosthodontics, Department of Head and Neck Surgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.

This clinical report describes the prosthodontic rehabilitation of a 22-year-old woman with a substantial treatment history of Ewing sarcoma of the left maxillary sinus. The patient was diagnosed with Ewing sarcoma at the age of 7 years and went through chemotherapy, radiation, surgical resection, and free-flap reconstruction, initially without prosthodontic rehabilitation. The patient aged 22 years was referred to the oral oncology clinic at The University of Texas MD Anderson Cancer Center for prosthodontic treatment. Read More

Can J Ophthalmol 2018 Dec 9;53(6):e247-e249. Epub 2018 Apr 9.

Seoul National University College of Medicine, Seoul, Korea; Seoul National University Bundang Hospital, Seongnam, Korea.