871 results match your criteria Simple Prostatectomy


Die präoperative Anwendung von Dutasterid hat keine Auswirkung auf intraoperative Blutungen bei transvesikaler offener einfacher Prostatektomie zur Behandlung der benignen Prostatahyperplasie.

Aktuelle Urol 2020 May 19. Epub 2020 May 19.

Bakirkoy Dr Sadi Konuk Training and Research Hospital, Urology, Istanbul.

Objective: There are a few studies in the literature investigating the effect of preoperative dutasteride use on bleeding in open simple prostatectomy. We aimed to evaluate the effect of preoperative dutasteride use on perioperative bleeding during open simple prostatectomy.

Methods: We retrospectively analyzed the medical records of all patients who underwent transvesical open prostatectomy due to benign prostatic hyperplasia in our institution between 2008 and 2018. Read More

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http://dx.doi.org/10.1055/a-1167-0465DOI Listing

Transvesical versus Transabdominal - Which is the Best Approach to Bladder Diverticulectomy using the Single Port Robotic System?

Urology 2020 May 20. Epub 2020 May 20.

Department of Urology, University of Rochester Medical Center (URMC), Rochester, New York, U.S.

Introduction And Objective: Application of the Single Port (SP) robotic platform [Intuitive®] is expanding.  Using two illustrative examples of bladder diverticula (BD) resulting from bladder outflow obstruction (BOO), we describe in this video our techniques utilising SP to treat BD via Extravesical (EV#1) and Transvesical (TV#2) approaches.

Methods: In EV#1, a 56 year old, with BOO due to benign prostate enlargement (BPE) of a 30ml prostate, and a 5cm BD, was treated with RABD-SP. Read More

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http://dx.doi.org/10.1016/j.urology.2020.05.018DOI Listing

Single port robotic radical prostatectomy: a systematic review.

Transl Androl Urol 2020 Apr;9(2):898-905

Department of Urology, University of Illinois at Chicago, Chicago, IL, USA.

Several studies have assessed the safety and feasibility of single port robot-assisted radical prostatectomy using different and custom built robotic-assisted technology. In part due to the non-standardized nature of these approaches, single site robotic prostatectomy has not been widely adopted. With the recent approval of the da Vinci (Intuitive Surgical, Sunnyvale CA) Single Port (SP) platform, there has been a renewed interest in single site robotic-assisted prostatectomy and several institutions have begun reporting their initial experiences with this technique. Read More

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http://dx.doi.org/10.21037/tau.2019.11.05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215004PMC

PreImplantation Factor immunohistochemical expression correlates with prostate cancer aggressiveness.

Int J Biol Markers 2020 May 11:1724600820919969. Epub 2020 May 11.

BioIncept, LLC & The Society for the Investigation of Early Pregnancy (SIEP), New York, NY, USA.

Background: The PreImplantation Factor (PIF)-a peptide secreted by viable embryos-exerts autotrophic protective effects, promotes endometrial receptivity and controls trophoblast invasion. Synthetic PIF (sPIF) has both immune-protective and regenerative properties, and reduces oxidative stress and protein misfolding. PIF is detected by immunohistochemistry (IHC) in hyperplastic endometriotic lesions and advanced uterine cancer. Read More

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http://dx.doi.org/10.1177/1724600820919969DOI Listing

Clavien System Classification of Complications Developed following Laparoscopic Urological Operations Applied in our Clinic.

Sisli Etfal Hastan Tip Bul 2019 27;53(3):228-239. Epub 2019 Aug 27.

Department of Urology, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul, Turkey.

Objectives: We analyzed the complications of laparoscopic surgery using Clavien system classification on 396 urological procedures performed at our institution between 2005-2009.

Methods: A retrospective analysis was performed, focusing on complications associated with 396 laparoscopic surgeries performed between 2005 and 2009, which included radical and simple nephrectomy (n=188), partial nephrectomy (n=29), pyeloplasty (n=78), sacrocolpopexy (n=16) and radical prostatectomy (n=85). Complication data were tabulated according to the case number, procedure type, patient age, the American Society of Anesthesiologists score (ASA), Clavien classification system and annual complication rate during this study. Read More

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http://dx.doi.org/10.14744/SEMB.2018.98700DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192280PMC

How accurately can multiparametric magnetic resonance imaging measure the tumour volume of a prostate cancer? Results of a systematic review.

J Med Imaging Radiat Oncol 2020 May 4. Epub 2020 May 4.

Brain-Behaviour Research Group, University of New England, Armidale, New South Wales, Australia.

The tumour volume of a cancer within the prostate gland is commonly measured with multiparametric MRI. The measurement has a role in many clinical scenarios including focal therapy, but the accuracy of it has never been systematically reviewed. We included articles if they compared tumour volume measurements obtained by mpMRI with a reference volume measurement obtained after radical prostatectomy. Read More

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http://dx.doi.org/10.1111/1754-9485.13035DOI Listing

Intermediate-term Urinary Function and Complication Outcomes After Robot-Assisted Simple Prostatectomy.

Urology 2020 Apr 22. Epub 2020 Apr 22.

Department of Urology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA.

Objective: To assess the incidence of delayed complications after robot-assisted simple prostatectomy and evaluate postoperative lower urinary tract symptoms (LUTS) as a function of time with intermediate-term follow-up.

Methods: We retrospectively reviewed 150 patients who underwent robot-assisted simple prostatectomy between May, 2013 and January, 2019. Indication for surgery was bothersome LUTS refractory to medical management and prostate volume ≥80 milliliters. Read More

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http://dx.doi.org/10.1016/j.urology.2020.04.055DOI Listing

Robot-Assisted Simple Prostatectomy: Illustration of a Simplified Extraperitoneal Transcapsular Technique.

Videourology (New Rochelle) 2019 8;33(6). Epub 2019 Apr 8.

Department of Urology, University of Rochester Medical Center (URMC), Rochester, New York.

Robot-assisted simple prostatectomy (RASP) performed with the extraperitoneal (EP) technique (RASP-EP) minimizes the risk of bowel injury, particularly when bowel adhesions may be expected to be prominent, by negating the need to be in the transperitoneal space. However, there is a perception of its technical difficulty owing to the limited space that can be expanded within the space of Retzius. We aimed to describe, in the accompanying video, the step-by-step approach for a technically proficient procedure. Read More

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http://dx.doi.org/10.1089/vid.2019.0032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147249PMC

[Benign prostatic hyperplasia : New and treatment-relevant aspects from the DGU guidelines].

Urologe A 2020 May;59(5):544-549

Urologische Praxisgemeinschaft, Hamburg-Blankenese, Hamburg, Deutschland.

The diagnosis and treatment of lower urinary tract symptoms (LUTS) due to benign prostatic enlargement plays an important role in daily urological practice. Therefore, a targeted and resource-saving approach is essential. A rational base-line work-up of our patients provides the necessary information for obtaining the diagnosis and only needs to be expanded in individual cases. Read More

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http://dx.doi.org/10.1007/s00120-020-01184-yDOI Listing

Is Holmium Laser Enucleation of the Prostate a Good Surgical Alternative in Benign Prostatic Hyperplasia Management? A Review Article.

J Lasers Med Sci 2020 15;11(2):197-203. Epub 2020 Mar 15.

Laser Application in Medical Science Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Several therapeutic approaches such as holmium laser enucleation of the prostate (HoLEP) have been introduced to relieve bladder outlet obstruction caused by benign prostatic hyperplasia (BPH). Compared with other techniques including the transurethral resection of the prostate (TURP) and simple open prostatectomy, HoLEP results in a shorter hospital stay and catheterization time and fewer blood loss and transfusions. HoLEP is a size-independent treatment option for BPH with average gland size from 36 g to 170 g. Read More

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http://dx.doi.org/10.34172/jlms.2020.33DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118502PMC

Robotic Simple Prostatectomy: Why and How?

Int Neurourol J 2020 Mar 31;24(1):12-20. Epub 2020 Mar 31.

Department of Urology, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea.

Increasingly many studies have presented robotic simple prostatectomy (RSP) as a surgical treatment option for large benign prostatic hyperplasia (BPH) weighing 80-100 g or more. In this review, some frequently used RSP techniques are described, along with an analysis of the literature on the efficacy and complications of RSP and differences in treatment results compared with other surgical methods. RSP has the advantage of a short learning curve for surgeons with experience in robotic surgery. Read More

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http://dx.doi.org/10.5213/inj.2040018.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136446PMC

Combined systematic versus stand-alone multiparametric MRI-guided targeted fusion biopsy: nomogram prediction of non-organ-confined prostate cancer.

World J Urol 2020 Apr 5. Epub 2020 Apr 5.

Martini-Klinik, Prostate Cancer Center Hamburg-Eppendorf, Hamburg, Germany.

Objective: Based on unfavorable oncological and functional outcomes of non-organ-confined (NOC) prostate cancer (PCa), defined as ≥ pT3, pN1 or both, we aimed to develop a NOC prediction tool based on multiparametric MRI-guided targeted fusion biopsy (TBx).

Materials And Methods: Analyses were restricted to 594 patients with simultaneous PCa detection at systematic biopsy (SBx), TBx and subsequent radical prostatectomy (RP) at our institution. Development (n = 396; cohort 1) and validation cohorts (n = 198; cohort 2) were used to develop and validate the NOC nomogram. Read More

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http://dx.doi.org/10.1007/s00345-020-03176-1DOI Listing

Thulium Laser Vapoenucleation of the Prostate (ThuVEP) in Men at High Cardiovascular Risk and on Antithrombotic Therapy: A Single-Center Experience.

J Clin Med 2020 Mar 27;9(4). Epub 2020 Mar 27.

Department of Urology, IRCCS INRCA, 60127 Ancona, Italy.

Bleeding is the most common complication of transurethral resection of the prostate and simple open prostatectomy, especially in men on antiplatelet/anticoagulant therapy. The present study aimed to evaluate the safety and effectiveness of thulium laser vapoenucleation of the prostate (ThuVEP) for benign prostatic hyperplasia in patients on chronic antithrombotic medications. Between January 2015 and December 2019, 88 men underwent the procedure under antithrombotic agents in our center. Read More

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http://dx.doi.org/10.3390/jcm9040917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231078PMC

Robot-assisted simple prostatectomy versus open simple prostatectomy: a single-center comparison.

World J Urol 2020 Mar 28. Epub 2020 Mar 28.

Department of Urology, University Medical Center, Johannes Gutenberg University, Mainz, Germany.

Purpose: Open simple prostatectomy (OSP) is a standard surgical technique for patients with benign prostatic hyperplasia with prostate size larger than 80 ml. As a minimally invasive approach, robot-assisted simple prostatectomy (RASP) emerged as a feasible surgical alternative. Currently, there are no definite recommendations for the standard use of RASP. Read More

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http://dx.doi.org/10.1007/s00345-020-03168-1DOI Listing

Stepwise Description and Outcomes of Bladder Neck Sparing Robot-Assisted Simple Prostatectomy.

J Endourol 2020 May 21;34(5):588-593. Epub 2020 Apr 21.

Section of Urology, Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

To present a stepwise description and outcomes of bladder neck sparing (BNS) robot-assisted simple prostatectomy (RASP). Between March 2015 and December 2018, 30 consecutive patients with benign prostate hyperplasia underwent BNS RASP. Baseline characteristics, and intraoperative and postoperative variables were retrospectively abstracted. Read More

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http://dx.doi.org/10.1089/end.2020.0078DOI Listing

Single-Port Percutaneous Transvesical Simple Prostatectomy Using the SP Robotic System: Initial Clinical Experience.

Urology 2020 Mar 11. Epub 2020 Mar 11.

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH.

Objective: To present our initial experience with single-port percutaneous transvesical simple prostatectomy using the novel SP robotic surgical system.

Methods: Ten patients underwent single-port transvesical simple prostatectomy between February and November 2019. Percutaneous access to the bladder dome was made and all SP instruments were inserted through the SP multichannel cannula directly into the bladder. Read More

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http://dx.doi.org/10.1016/j.urology.2020.02.024DOI Listing

The role of fatal family history and mode of inheritance in prostate cancer for long-term outcomes following radical prostatectomy.

World J Urol 2020 Mar 11. Epub 2020 Mar 11.

Technical University of Munich, School of Medicine, Klinikum rechts der Isar, Department of Urology, Munich, Germany.

Purpose: To determine whether fatal family history (FFH) or mode of inheritance in prostate cancer (PCa) has an impact on long-term outcomes following radical prostatectomy (RP).

Methods: 1076 PCa patients after RP with at least one deceased first-degree relative with PCa were included and stratified by FFH (four subgroups: fraternal, paternal, multiple, and none) and by mode of inheritance (two subgroups: male to male, non-male to male). We compared clinicopathological characteristics between subgroups with Fisher's exact or Chi-square tests. Read More

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http://dx.doi.org/10.1007/s00345-020-03147-6DOI Listing

Laparoscopic radical prostatectomy and extended pelvic lymph node dissection: a combined technique.

Wideochir Inne Tech Maloinwazyjne 2020 Mar 2;15(1):192-198. Epub 2020 Feb 2.

Department of Urooncology, M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland.

Introduction: The important part of radical prostatectomy (RP) for high risk (HR) is extended pelvic lymph node dissection (ePLND). This method consists of two stages of surgery usually performed at the compartment (pre- or transperineally).

Aim: We present our new combined technique of RP using two different approaches: a pre-peritoneal approach for laparoscopic radical prostatectomy (LRP) and a transperitoneal approach for ePLND. Read More

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http://dx.doi.org/10.5114/wiitm.2019.86810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020702PMC

Interobserver agreement of [Ga]Ga-PSMA-11 PET/CT images interpretation in men with newly diagnosed prostate cancer.

EJNMMI Res 2020 Feb 28;10(1):15. Epub 2020 Feb 28.

Division of Nuclear Medicine and Oncological Imaging, Department of Medical Physics, CHU of Liege, Avenue de l'Hôpital, 1, 4000, Liege, Belgium.

Background: Prostate-specific membrane antigen (PSMA) ligand PET/CT has already provided promising results in prostate cancer (PC) imaging, yet simple and reproductible reporting criteria are still lacking. This study aimed at retrospectively evaluating interobserver agreement of [Ga]Ga-PSMA-11 PET/CT images interpretation according to PC molecular imaging standardized evaluation (PROMISE) criteria and reproducibility of PSMA reporting and data systems (RADS).

Methods: Forty-three patients with newly diagnosed, histologically proven intermediate- or high-risk PC, eligible for radical prostatectomy and who underwent [Ga]Ga-PSMA-11 PET/CT before surgery were retrospectively included. Read More

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http://dx.doi.org/10.1186/s13550-020-0596-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048889PMC
February 2020

[Multicenter comparison of complications after robot-assisted and open simple prostatectomy].

Urologe A 2020 May;59(5):565-572

Klinik für Urologie und Kinderurologie, Universitätsklinikum Schleswig-Holstein - Campus Kiel, Arnold-Heller-Straße 3, 24105, Kiel, Deutschland.

Introduction: Robot-assisted simple prostatectomy (RASP) is a relatively new minimally invasive procedure for surgical treatment to manage symptomatic, therapy-refractory benign prostate hyperplasia (BPH) in prostate volumes >80 cm. Thus, postoperative morbidity based on Clavien-Dindo and hematological parameters in RASP and open simple prostatectomy (OSP) procedures are examined.

Patients And Methods: We retrospectively reviewed a total of 78 patients: 39 patients underwent RAPS and 39 OSP. Read More

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http://dx.doi.org/10.1007/s00120-020-01141-9DOI Listing

Clinicopathological characteristics of glomeruloid architecture in prostate cancer.

Mod Pathol 2020 Feb 20. Epub 2020 Feb 20.

Department of Pathology, Erasmus MC, University Medical Center, P.O. Box 2040, 3000, Rotterdam, The Netherlands.

Glomeruloid architecture is the least common Gleason 4 growth pattern in prostate adenocarcinoma. Its clinicopathological features and relation with cribriform architecture, which has been recognized as an adverse feature, remains to be established. Our objective was to investigate clinicopathological features of glomeruloid architecture in radical prostatectomies. Read More

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http://dx.doi.org/10.1038/s41379-020-0507-2DOI Listing
February 2020

[Anastomosis stenosis after radical prostatectomy and bladder neck stenosis after benign prostate hyperplasia treatment: reconstructive options].

Urologe A 2020 Apr;59(4):398-407

Klinik für Urologie, Asklepios Klinik Barmbek, Rübenkamp 220, 22307, Hamburg, Deutschland.

Bladder neck stenosis (BNS) after simple prostatectomy and vesicourethral anastomosis stenosis (VUAS) after radical prostatectomy for prostate cancer are common sequelae. However, the two entities differ in their pathology, anatomy and their surgical results. VUAS has an incidence of 0. Read More

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http://dx.doi.org/10.1007/s00120-020-01143-7DOI Listing

National discrepancies in residency training of open simple prostatectomy for benign prostatic enlargement: Redefining our gold standard.

Can Urol Assoc J 2020 Jan 20. Epub 2020 Jan 20.

Division of Urology, Centre hospitalier de l'Université de Montréal, Université de Montréal, Montreal, QC, Canada.

Introduction: In light of the recent Canadian Urological Association (CUA) and other urological association (America Urological Association, European Association of Urology) recommendations for the treatment of benign prostate hyperplasia (BPH) with lower urinary tract symptoms (LUTS), open simple prostatectomy (OSP) remains the recommended approach for large prostates with measured volumes over 80 cc. We sought to assess the current state of OSP and other BPH surgical training across Canadian urology residency programs and the use of guideline-recommended imagery prior to BPH surgery.

Methods: A survey was distributed among Canadian urology program directors in June 2019. Read More

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http://dx.doi.org/10.5489/cuaj.6242DOI Listing
January 2020

Laparoscopic simple prostatectomy: a large single center prospective cohort study.

Minerva Urol Nefrol 2019 Dec 12. Epub 2019 Dec 12.

Complexo Hospitalario Universitario de Pontevedra, Galicia, Spain.

Backround: Aim of our study was to analyse outcomes and safety of laparoscopic simple prostatectomy (LSP) in a high volume center.

Methods: A consecutive series of men with lower urinary tract symptoms and large prostates (>80cc) prospectively enrolled between November 2015 and December 2017 in one center. All patients underwent laparoscopic simple prostatectomy. Read More

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http://dx.doi.org/10.23736/S0393-2249.19.03567-7DOI Listing
December 2019

Modified simple prostatectomy: an approach to address large volume BPH and associated prostate cancers.

J Robot Surg 2019 Dec 10. Epub 2019 Dec 10.

Adventhealth Global Robotics Institute, 410 Celebration Pl., Celebration, FL, 34747, USA.

Simple prostatectomy is an option for management of patients with enlarged prostates and obstructive symptoms. However, the guidelines still do not state a gold-standard treatment for men with BPH and some of these patients with BPH are also known to harbor prostate cancer. This issue can be a challenge because, in the traditional simple prostatectomy, the prostate capsule is often left in place, and that is usually the area of the prostate cancers. Read More

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http://dx.doi.org/10.1007/s11701-019-01038-6DOI Listing
December 2019

Development of Research Agenda in Prostate Artery Embolization: Summary of Society of Interventional Radiology Consensus Panel.

J Vasc Interv Radiol 2020 Jan 23;31(1):108-113. Epub 2019 Nov 23.

Department of Radiology, MedStar Georgetown University, Washington, DC.

Purpose: To summarize the Society of Interventional Radiology Foundation's Research Consensus Panel development of a research agenda on prostate artery embolization (PAE).

Materials And Methods: PAE for the treatment of lower urinary tract symptoms has been shown to be safe and effective in decreasing symptoms and prostate size. Lack of randomized controlled trials (RCTs) on PAE in the United States has prevented inclusion in American Urologic Association guideline recommendations for treatment of lower urinary tract symptoms resulting from benign prostatic hyperplasia. Read More

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http://dx.doi.org/10.1016/j.jvir.2019.09.019DOI Listing
January 2020

Giant benign prostatic hyperplasia: A case report.

Urol Case Rep 2020 Jan 19;28:101051. Epub 2019 Oct 19.

Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Benign prostatic hyperplasia (BPH) is prostate weighting f over 500g and is usually public in men older than fifty years. A case of 78-year-old man was referred to Sina hospital complaining of urinary frequency. His total prostate-specific antigen was 17. Read More

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http://dx.doi.org/10.1016/j.eucr.2019.101051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833462PMC
January 2020

[Repair of Iatrogenic Recto-Urethral Fistulas : Experience of 6 Cases].

Authors:
Koji Yoshimura

Hinyokika Kiyo 2019 Sep;65(9):355-361

The Department of Urology, Shizuoka General Hospital.

I repaired iatrogenic recto-urethral fistulas (RUF) in 6 patients. All the fistulas had developed after surgery, 5 for prostate cancer (prostatectomy) and the remaining one for pelvic solitary fibrous tumor. All of them were"simple"fistulas. Read More

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http://dx.doi.org/10.14989/ActaUrolJap_65_9_355DOI Listing
September 2019

Fundamentals of prosthetic urology.

Asian J Androl 2020 Jan-Feb;22(1):20-27

Department of Urology, Tulane University School of Medicine, 1430 Tulane Avenue, 86-42, New Orleans, LA 70112-2699, USA.

The field of prosthetic urology demonstrates the striking impact that simple devices can have on quality of life. Penile prosthesis and artificial urinary sphincter implantation are the cornerstone procedures on which this specialty focuses. Modern research largely concentrates on decreasing the rates of complication and infection, as the current devices offer superior rates of satisfaction when revision is not necessary. Read More

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http://dx.doi.org/10.4103/aja.aja_108_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958978PMC
November 2019

The burden of urological disease in Zomba, Malawi: A needs assessment in a sub-Saharan tertiary care center.

Can Urol Assoc J 2020 Jan 17;14(1):E6-E12. Epub 2019 Jun 17.

Division of Urology, Michael Garron Hospital, Toronto, ON, Canada.

Introduction: A large part of the developing world continues to lack access to surgical care. Urology remains one of the least represented surgical subspecialties in global health. To begin understanding the burden of urological illness in sub-Saharan Africa, we sought to characterize all patients presenting to a tertiary care hospital in Malawi with a urological diagnosis or related complaint in the past year. Read More

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http://dx.doi.org/10.5489/cuaj.5837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955180PMC
January 2020
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What is the standard surgical approach to large volume BPE? Systematic review of existing randomized clinical trials.

Minerva Urol Nefrol 2020 Feb 10;72(1):22-29. Epub 2019 Oct 10.

Department of Urology, University of Florence, Florence, Italy.

Introduction: In the past years several reviews have analysed different aspects of surgical techniques for patients with LUTS due to BPE however none of them have concentrated on large prostates treatment exclusively. Moreover, none of the reviews have focused on level 1 evidence which is essential to avoid bias and wrong conclusions. With this knowledge in mind, aim of the present review is to analyze the available randomized clinical trials assessing the management of patients with big prostates (>80 cc). Read More

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http://dx.doi.org/10.23736/S0393-2249.19.03589-6DOI Listing
February 2020
1 Read

Laparoscopic simple prostatectomy: complications and functional results after 5 years of follow-up.

Minerva Urol Nefrol 2019 Oct 10. Epub 2019 Oct 10.

Department of Urology, University of Turin, San Luigi Gonzaga Hospital, Orbassano, Turin, Italy.

Background: The aim was to investigate complications and functional results in a cohort of patients who underwent extraperitoneoscopic transcapsular laparoscopic simple prostatectomy (LSP) for large prostate adenomas with a minimum follow-up of 5 years.

Methods: We retrospectively reviewed data obtained from our prospectively maintained database of patients treated with LSP at our institution between January 2004 and June 2012, with at least 5 years of reported follow-up data. Demographics, perioperative results, early and late complications, and functional results were evaluated. Read More

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http://dx.doi.org/10.23736/S0393-2249.19.03526-4DOI Listing
October 2019
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Preventing Excess Narcotic Prescriptions in New Robotic Surgery Discharges: The PENN Prospective Cohort Quality Improvement Initiative.

J Endourol 2020 Jan 8;34(1):48-53. Epub 2019 Nov 8.

Division of Urology, Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

To reduce the amount of opioids prescribed at discharge after robotic surgery, we hypothesized that the majority patients do not require opioids for pain control after robotic urologic oncologic procedures. This prospective study aimed to reduce opioids prescribed at discharge after robot-assisted radical prostatectomy (RARP), robot-assisted radical nephrectomy (RARN), and robot-assisted partial nephrectomy (RAPN). Before 9/2018, 100% of patients were discharged on varying amounts of oxycodone (range: 75-337. Read More

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http://dx.doi.org/10.1089/end.2019.0362DOI Listing
January 2020
8 Reads

Initial experience with extraperitoneal robotic-assisted simple prostatectomy using the da Vinci SP surgical system.

J Robot Surg 2019 Sep 27. Epub 2019 Sep 27.

Department of Urology, University of Texas Southwestern, 2001 Inwood Dr., WCB3, Suite 4.878, MC 9110, Dallas, TX, 75390, USA.

Robotic-assisted simple prostatectomy (RASP) has emerged as a safe and effective treatment option for symptomatic patients with lower urinary tract symptoms related to significant benign prostatic enlargement (BPE) above 80 g. The recent release of the da Vinci SP robotic system (Intuitive, Sunnyvale, CA, USA) continues to advance the minimally invasive nature of robotic surgical technology. We now report our institution's initial experience performing RASP using the da Vinci SP robotic system. Read More

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http://dx.doi.org/10.1007/s11701-019-01029-7DOI Listing
September 2019
3 Reads

Comparative Effectiveness of Transurethral Prostate Procedures at Enabling Urologic Medication Discontinuation: A Retrospective Analysis.

Urology 2019 12 19;134:192-198. Epub 2019 Sep 19.

Lerner College of Medicine, Education Institute, Cleveland Clinic, Cleveland, OH; Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH. Electronic address:

Objective: To test the hypothesis that transurethral prostate procedures (TUPPs) eliminating tissue result in greater medication discontinuation and lower de novo initiation rates than procedures inducing tissue necrosis.

Methods: Retrospective review of all men undergoing first time TUPPs at a large tertiary center from 2001 to 2016 was completed. Procedure type and urologic medication use before, 3-12 months after, and greater than 12 months after TUPP were analyzed with simple open prostatectomy as a comparator. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00904295193081
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http://dx.doi.org/10.1016/j.urology.2019.07.039DOI Listing
December 2019
8 Reads

Holmium laser enucleation of the prostate (HoLEP): a review and update.

Can J Urol 2019 08;26(4 Suppl 1):13-19

Department of Urology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

Introduction: Lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) is one of the most common diseases affecting the aging man, with almost 80% of men greater than 70 affected. Historically, transurethral resection of the prostate (TURP) has been considered the historical gold standard in the treatment of LUTS due to BPH for many years, contemporary literature indicates that holmium laser enucleation of the prostate (HoLEP) has replaced TURP and open simple prostatectomy as the size independent surgical gold standard for BPH treatment.

Materials And Methods: In this review, we discuss the current techniques utilized, outcomes and safety, as well as the long term durability of results. Read More

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August 2019
6 Reads

Improved Prostate Cancer Biopsy Grading by Incorporation of Invasive Cribriform and Intraductal Carcinoma in the 2014 Grade Groups.

Eur Urol 2020 Feb 19;77(2):191-198. Epub 2019 Aug 19.

Department of Urology, Erasmus University Medical Centre, Rotterdam, The Netherlands.

Background: Grade groups (GGs) are an important parameter for therapeutic decision making in prostate cancer (Pca) patients. Invasive cribriform and/or intraductal carcinoma (CR/IDC) has an independent prognostic value for disease outcome, but are not included in the GG limiting their clinical use.

Objective: To perform a proof-of-principle study incorporating CR/IDC in the current GG. Read More

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http://dx.doi.org/10.1016/j.eururo.2019.07.051DOI Listing
February 2020
4 Reads

Artificial intelligence-based versus manual assessment of prostate cancer in the prostate gland: a method comparison study.

Clin Physiol Funct Imaging 2019 Nov 8;39(6):399-406. Epub 2019 Sep 8.

Department of Clinical Research, University of Southern Denmark, Odense, Denmark.

Aim: To test the feasibility of a fully automated artificial intelligence-based method providing PET measures of prostate cancer (PCa).

Methods: A convolutional neural network (CNN) was trained for automated measurements in F-choline (FCH) PET/CT scans obtained prior to radical prostatectomy (RP) in 45 patients with newly diagnosed PCa. Automated values were obtained for prostate volume, maximal standardized uptake value (SUV ), mean standardized uptake value of voxels considered abnormal (SUV ) and volume of abnormal voxels (Vol ). Read More

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http://dx.doi.org/10.1111/cpf.12592DOI Listing
November 2019
3 Reads

[The current status of surgical treatment of benign prostatic hyperplasia with volume over 80 .]

Urologiia 2019 Jul(3):128-133

Department of Urology of Federal Clinical Center for HMT, Khimki, Russia.

According to European Association of Urology (EAU), an open simple prostatectomy, holmium laser and bipolar enucleation represent current standard methods for surgical treatment of benign prostatic hyperplasia (BPH) with volume over 80 ml. The transurethral resection of prostate, thulium laser enucleation and laser vaporization are second-line methods. In addition, some novel interventions are currently being developing. Read More

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July 2019
6 Reads

Quantitation of Femtomolar-Level Protein Biomarkers Using a Simple Microbubbling Digital Assay and Bright-Field Smartphone Imaging.

Angew Chem Int Ed Engl 2019 09 21;58(39):13922-13928. Epub 2019 Aug 21.

Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.

Quantitating ultra-low concentrations of protein biomarkers is critical for early disease diagnosis and treatment. However, most current point-of-care (POC) assays are limited in sensitivity. Herein, we introduce an ultra-sensitive and facile microbubbling assay for the quantification of protein biomarkers with a digital-readout method that requires only a smartphone camera. Read More

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http://dx.doi.org/10.1002/anie.201906856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211056PMC
September 2019
4 Reads

Best practices in near-infrared fluorescence imaging with indocyanine green (NIRF/ICG)-guided robotic urologic surgery: a systematic review-based expert consensus.

World J Urol 2020 Apr 8;38(4):883-896. Epub 2019 Jul 8.

USC Institute of Urology and Catherine and Joseph Aresty Department of Urology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Purpose: The aim of the present study is to investigate the impact of the near-infrared (NIRF) technology with indocyanine green (ICG) in robotic urologic surgery by performing a systematic literature review and to provide evidence-based expert recommendations on best practices in this field.

Methods: All English language publications on NIRF/ICG-guided robotic urologic procedures were evaluated. We followed the PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analyses) statement to evaluate PubMed, Scopus and Web of Science™ databases (up to April 2019). Read More

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http://dx.doi.org/10.1007/s00345-019-02870-zDOI Listing
April 2020
4 Reads

Comparison Between Minimally Invasive Simple Prostatectomy and Open Simple Prostatectomy for Large Prostates: A Systematic Review and Meta-Analysis of Comparative Trials.

J Endourol 2019 09 26;33(9):767-776. Epub 2019 Jul 26.

Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.

Although previous studies have compared the minimally invasive simple prostatectomy (MISP) with open simple prostatectomy (OSP) for large prostates, there is still controversy. This study aims to provide the latest evidence for clinical practice. We systematically searched Science, EMBASE, PubMed, and Clinicalkey databases for articles comparing MISP and OSP for large prostates. Read More

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https://www.liebertpub.com/doi/10.1089/end.2019.0306
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http://dx.doi.org/10.1089/end.2019.0306DOI Listing
September 2019
8 Reads

The Role of Aquablation for the Surgical Treatment of LUTS/BPH.

Curr Urol Rep 2019 Jun 21;20(8):46. Epub 2019 Jun 21.

Division of Urology, Department of Surgery, University Health Network, University of Toronto, Toronto, Canada.

Purpose Of Review: To explore the potential applicability of a novel, heat-free, and robotically controlled ablative therapy for surgical management of benign prostatic enlargement.

Recent Findings: With the emergence of new technology to provide personalized care and overcome the complications associated with options such as TURP, holmium laser enucleation of the prostate, GreenLight laser, or simple prostatectomy, Aquablation has been studied across a variety of prostate volumes. The functional outcome of Aquablation seems to be uncompromised by prostate volume. Read More

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http://dx.doi.org/10.1007/s11934-019-0905-5DOI Listing
June 2019
4 Reads

Predicting side-specific prostate cancer extracapsular extension: a simple decision rule of PSA, biopsy, and MRI parameters.

Int Urol Nephrol 2019 Sep 10;51(9):1545-1552. Epub 2019 Jun 10.

Department of Urology, Medical University of Warsaw, Lindleya 4, 02-005, Warsaw, Poland.

Objective: To develop an easy-to-use side-specific tool for the prediction of prostate cancer extracapsular extension (ECE) using clinical, biopsy, and MRI parameters.

Materials And Methods: Retrospective analysis of patients who underwent radical prostatectomy preceded by staging multiparametric MRI of the prostate was performed. Multivariate logistic regression analysis was used to choose independent predictors of ECE. Read More

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http://dx.doi.org/10.1007/s11255-019-02195-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713688PMC
September 2019
6 Reads

TRIM24 as an independent prognostic biomarker for prostate cancer.

Urol Oncol 2019 09 7;37(9):576.e1-576.e10. Epub 2019 Jun 7.

Institute of Pathology, University Hospital Schleswig-Holstein, Luebeck, Germany; Pathology of the Research Center Borstel, Leibniz Lung Center, Borstel, Germany. Electronic address:

Introduction: Simply applicable biomarkers for prostate cancer patients predicting the clinical course are urgently needed. Recently, TRIM24 has been identified to promote androgen receptor signaling and to correlate with an aggressive prostate cancer phenotype. Based on these data, we proofed TRIM24 as a prognostic biomarker for risk stratification. Read More

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http://dx.doi.org/10.1016/j.urolonc.2019.05.006DOI Listing
September 2019
21 Reads

A single-center, retrospective review of robot-assisted laparoscopic prostatectomy with and without cryopreserved umbilical cord allograft in improving continence recovery.

J Robot Surg 2020 Apr 31;14(2):283-289. Epub 2019 May 31.

NJ Center for Prostate Cancer and Urology, 255 W Spring Valley Ave #101, Maywood, NJ, 07607, USA.

The objective of this study was to evaluate the safety and effectiveness of cryopreserved umbilical cord (UC) allograft as a nerve wrap around the neurovascular bundle (NVB) in accelerating return to continence after radical prostatectomy. A single-center, retrospective study was performed on 200 patients who underwent bilateral, nerve-sparing robot-assisted radical prostatectomy (RARP) with and without placement of UC around the NVBs (n = 100/group). Patients were excluded if they had previous simple or transurethral prostatectomy or history of pelvic radiation. Read More

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http://dx.doi.org/10.1007/s11701-019-00972-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125058PMC
April 2020
5 Reads

A simple algorithm to predict non-compliance with organ at risk dose-volume constraints when planning intensity modulated post-prostatectomy radiation treatment: 'Why we should put the CART before the horse'.

J Med Imaging Radiat Oncol 2019 Aug 28;63(4):546-551. Epub 2019 May 28.

Northern Sydney Cancer Centre, Radiation Oncology, Royal North Shore Hospital, St Leonards, New South Wales, Australia.

Introduction: It is not always apparent when the optimal IMRT/VMAT plan for post-prostatectomy radiotherapy (PPRT) has been achieved. Individual variation in patient anatomy is a key contributor. This study aimed to create a model to determine the probability of rectum and/or bladder doses exceeding planning goals based on individual patient anatomy prior to planning. Read More

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http://dx.doi.org/10.1111/1754-9485.12902DOI Listing
August 2019
8 Reads

Prostate cancer upgrading or downgrading of biopsy Gleason scores at radical prostatectomy: prediction of "regression to the mean" using routine clinical features with correlating biochemical relapse rates.

Asian J Androl 2019 Nov-Dec;21(6):598-604

Department of Urology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Recommendations for managing clinically localized prostate cancer are structured around clinical risk criteria, with prostate biopsy (PB) Gleason score (GS) being the most important factor. Biopsy to radical prostatectomy (RP) specimen upgrading/downgrading is well described, and is often the rationale for costly imaging or genomic studies. We present simple, no-cost analyses of clinical parameters to predict which GS 6 and GS 8 patients will change to GS 7 at prostatectomy. Read More

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http://dx.doi.org/10.4103/aja.aja_29_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859655PMC
May 2019
9 Reads

Improvement of Urinary Incontinence, Life Impact, and Depression and Anxiety With Modified Pelvic Floor Muscle Training After Radical Prostatectomy.

Am J Mens Health 2019 May-Jun;13(3):1557988319851618

4 Graduate Institute of Gerontology and Health Care Management, Chang Gung University of Science and Technology, Taoyuan City.

Prostate cancer ranks second among male cancers in the United States in terms of death rate. Robot-assisted surgery (RAS) is now offered as the standard surgical procedure performed for radical prostatectomy. Urinary incontinence and erectile dysfunction were common complications after RAS prostatectomy. Read More

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http://dx.doi.org/10.1177/1557988319851618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537297PMC
May 2019
6 Reads

Cognitive function, depression, and anxiety in patients undergoing radical prostatectomy with and without adjuvant treatment.

Neuropsychiatr Dis Treat 2019 5;15:819-829. Epub 2019 Apr 5.

Department of Clinical Neuropsychology, Nicolaus Copernicus University in Toruń, Collegium Medicum, Bydgoszcz, Poland,

Background: Prostate cancer (PC) is one of the most common malignant tumors in developed countries. Both PC and treatment for PC have an adverse impact on physical and mental well-being, and are associated with decreased quality of life. The aim of the present study was to examine the relationship between neuropsychological symptoms and clinical course in PC patients undergoing radical prostatectomy with or without adjunct therapy. Read More

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http://dx.doi.org/10.2147/NDT.S200501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454999PMC
April 2019
9 Reads