525,129 results match your criteria Simple Bone Cyst Imaging


Expostats: A Bayesian Toolkit to Aid the Interpretation of Occupational Exposure Measurements.

Ann Work Expo Health 2018 Dec 14. Epub 2018 Dec 14.

Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.

Introduction: Interpretation of exposure measurements has evolved into a framework based on the lognormal distribution. Most available practical tools are based on traditional frequentist statistical procedures that do not satisfactorily account for censored data and are not amenable to simple probabilistic risk statements. Bayesian methods offer promising solutions to these challenges. Read More

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December 2018

Vestibular dysfunction as cortical damage with amyotrophic lateral sclerosis.

J Neurol Sci 2018 Dec 5;397:4-8. Epub 2018 Dec 5.

Department of Neurology, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.

Background: Cortical damage in areas such as the frontal lobe is reported in amyotrophic lateral sclerosis (ALS). However, aside from executive dysfunction, the pathological significance of this cortical damage has yet to be clarified. The present study investigated the effects of cortical damage on vestibular function in ALS. Read More

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December 2018

A prediction method of speed-dependent walking patterns for healthy individuals.

Gait Posture 2018 Dec 5;68:280-284. Epub 2018 Dec 5.

Federal University of ABC, Neuroscience and Biomedical Engineering Programs, São Bernardo do Campo, São Paulo, Brazil. Electronic address:

Background: Gait speed is one of the main biomechanical determinants of human movement patterns. However, in clinical gait analysis, the effect of gait speed is generally not considered, and people with disabilities are usually compared with able-bodied individuals even though disabled people tend to walk slower.

Research Questions: This study proposes a simple way to predict the gait pattern of healthy individuals at a specific speed. Read More

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December 2018

Multi-segment spine kinematics: Relationship with dance training and low back pain.

Gait Posture 2018 Dec 4;68:274-279. Epub 2018 Dec 4.

Centre for Sport Research, School of Exercise and Nutrition Sciences, Deakin University, 221 Burwood Highway, Burwood, VIC 3125, Australia; Sport Performance Research Institute New Zealand, Auckland University of Technology, 17 Antares Place, Rosedale, Auckland 0632, New Zealand. Electronic address:

Background: Spine posture, range of motion (ROM) and movement asymmetry can contribute to low back pain (LBP). These variables may have greater impact in populations required to perform repetitive spine movements, such as dancers; however, there is limited evidence to support this.

Research Question: What is the influence of dance and LBP on spinal kinematics?

Methods: In this cross-sectional study, multi-segment spinal kinematics were examined in 60 female participants, including dancers (n = 21) and non-dancers (n = 39) with LBP (n = 33) and without LBP (n = 27). Read More

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December 2018
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Normal axillary thickness thresholds as a metric for nutritional status of children.

Clin Imaging 2018 Dec 1;54:57-62. Epub 2018 Dec 1.

Department of Radiology, University of Michigan Medical School, 3208C Medical Sciences Building 1, B1D502, Ann Arbor, MI 48109-5030, United States of America. Electronic address:

Introduction: Childhood pneumonia is a major cause of death in the 3rd world, and undernourishment increases the severity of the condition. We considered axillary thickness as a simple measurement to evaluate nutritional status that can be performed simultaneously with lung ultrasound. Our goal was to determine the distribution of axillary thickness in a cohort of children to determine a threshold for malnutrition. Read More

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December 2018
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Enhanced removal and detection of benzo[a]pyrene in environmental water samples using carbon dots-modified magnetic nanocomposites.

Ecotoxicol Environ Saf 2018 Dec 11;170:383-390. Epub 2018 Dec 11.

Faculty of Life Science and Technology, Kunming University of Science and Technology, Yunnan Province 650500, China. Electronic address:

Magnetic nanoparticles (MNPs) have already proven their efficacy in the disposal of a wide array of environmental contaminants in recent years. However, the difficulties in dispersibility and agglomeration of MNPs arising from its own physical and chemical properties limit its large-scale application. Herein, we fabricated the carbon dots/fatty acid-coated MNPs (CDs/C-FeO) through a facile and simple method. Read More

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December 2018

Human DNA degradation assessment and male DNA detection by quantitative-PCR followed by high-resolution melting analysis.

Forensic Sci Int 2018 Nov 29;295:1-7. Epub 2018 Nov 29.

Centro de Referencia en Identificación Genética Humana de la Universidad de Buenos Aires, Cátedra de Genética Forense y Servicio de Huellas Digitales Genéticas, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junin 956, CP 1113, Ciudad Autónoma de Buenos Aires, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas-CONICET, Godoy Cruz 2290, CP 1425, Ciudad Autónoma de Buenos Aires, Argentina.

We developed a q-PCR technique that simultaneously evaluates the extent of degradation and determines the gender of a human DNA donor. QYDEG HRM is a triplex real-time PCR whose products are analysed by high-resolution melting (HRM). The system produces three amplicons: (1) transducin (beta)-like 1, Y-linked (TBL1Y) (84bp); (2) large-target sequence (DGlt) (244bp); and (3) small-target sequence (DGst) (152bp). Read More

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November 2018

Microcontainers for protection of oral vaccines, in vitro and in vivo evaluation.

J Control Release 2018 Dec 11. Epub 2018 Dec 11.

Department of Micro- and Nanotechnology, Technical University of Denmark, Oersteds Plads 345C, 2800 Kgs., Lyngby, Denmark.

Oral vaccines are highly desirable due to simple logistics, mass vaccination potential and for mucosal immunity. Subunit vaccines are preferred due to high safety, but are inherently difficult to deliver orally, thus providing motivation for the use of advanced oral delivery systems. Polymeric devices in micrometer size (microcontainers) were tested here for this purpose. Read More

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December 2018
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Assessment of riparian vegetation characteristics in Mediterranean headwaters regulated by check dams using multivariate statistical techniques.

Sci Total Environ 2018 Dec 5;657:597-607. Epub 2018 Dec 5.

Department "Agraria", University "Mediterranea" of Reggio Calabria, Località Feo di Vito - I, 89122 Reggio Calabria, Italy.

In mountainous torrents of the Mediterranean environment the riparian vegetation is strongly influenced by the presence of engineering control works, since these structures bring heavy modifications in channel geometry, hydraulic regime and bed sediment size. Previous investigations have shown high linear correlations between physical (section shape, profile slope, specific discharge, surface and subsurface size of the channel bed) and vegetation (development, structure and biodiversity) indicators in headwater channels with check dams of Calabrian (Southern Italy) torrents. Based on these findings, this study applies multivariate statistical techniques (Principal Component Analysis and Partial Least Square Regression) to identify in the same study headwaters new synthetic explanatory variables, representative of the different transects (upstream, downstream or intermediate, compared to the check dam location) and develop predictive models of riparian vegetation characteristics. Read More

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December 2018

Multivariate analysis and modeling of soil quality indicators in long-term management systems.

Sci Total Environ 2018 Dec 4;657:457-465. Epub 2018 Dec 4.

Department of Plant Production, São Paulo State University-UNESP, 14884-900 Jaboticabal, SP, Brazil. Electronic address:

Soil management systems, as well as the long-term application of nitrogen fertilization, might promote changes in soil quality (SQ). The knowledge of how agronomic practices influence SQ is the main factor in the development of most sustainable management systems. Thus, the aim of this study was to evaluate the influence of long-term management systems on SQ through the analysis of 10 soil quality indicators (SQIs), to select the most sensitive SQIs through principal components analysis (PCA) and to propose a mathematical model that could estimate the activities of enzymes based on SQI values with simple and low-cost procedures in relation to enzyme measurement. Read More

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December 2018

Surgical Outcomes of Complex versus Simple Segmentectomy for Stage I Non-Small Cell Lung Cancer.

Ann Thorac Surg 2018 Dec 11. Epub 2018 Dec 11.

Department of Surgical Oncology Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan. Electronic address:

Background: As segmentectomy becomes widely used for lung cancer treatment, "complex segmentectomy," which makes several, intricate intersegmental planes, remains controversial because of procedural complexity and risk of increased complications and incurability. Questions remain regarding mortality, morbidity, surgical margin, lymph nodes dissection, and postoperative pulmonary function. We evaluated operative and postoperative outcomes of complex compared to simple segmentectomy. Read More

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December 2018

Design and methodology of a cluster-randomized trial in early care and education centers to meet physical activity guidelines: Sustainability via Active Garden Education (SAGE).

Contemp Clin Trials 2018 Dec 11. Epub 2018 Dec 11.

Center for Health Promotion and Disease Prevention, College of Nursing and Health Innovation, Arizona State University, Phoenix, AZ, United States.

Strategies are needed to help early care and education centers (ECEC) comply with policies to meet daily physical activity and fruit and vegetable guidelines for young children. This manuscript describes the design and methodology of Sustainability via Active Garden Education (SAGE), a 12-session cluster-randomized controlled crossover design trial using community-based participatory research (CBPR) to test a garden-based ECEC physical activity and fruit and vegetables promotion intervention for young children aged 3-5 years in 20 sites. The SAGE curriculum uses the plant lifecycle as a metaphor for human development. Read More

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December 2018

Impact of material properties and process variables on the residence time distribution in twin screw feeding equipment.

Int J Pharm 2018 Dec 11. Epub 2018 Dec 11.

Laboratory of Pharmaceutical Technology, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, B-9000 Ghent, Belgium.

Screw feeders are integrated as dispensing units in most continuous manufacturing platforms. Hence, characterizing and modelling the residence time distribution (RTD) of materials in feeders is indispensable to understand the traceability of raw materials from the drum till tablet, enabling the separation of non-confirming material. The proposed methodology addressed this leap in knowledge by characterizing materials, performing RTD trials according to an experimental design, applying RTD models and establishing a partial least square (PLS) regression model that links the material properties and process variables with the RTD responses as outputs. Read More

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December 2018

Comparison of stool examination techniques to detect Opisthorchis viverrini in low intensity infection.

Acta Trop 2018 Dec 11. Epub 2018 Dec 11.

Department of Parasitology, Phramongkutklao College of Medicine, Bangkok, 10400, Thailand. Electronic address:

Opisthorchiasis, caused by Opisthorchis viverrini, remains the public health significance in Thailand, particularly in the northeastern region. Number of parasitological techniques is available for diagnosis. However, the detection the parasite's eggs in stool still referred as gold standard. Read More

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December 2018

Genome survey sequencing for the characterization of genetic background of Dracaena cambodiana and its defense response during dragon's blood formation.

PLoS One 2018 14;13(12):e0209258. Epub 2018 Dec 14.

Key Laboratory of Biology and Genetic Resources of Tropical Crops of Ministry of Agriculture and Rural Affairs, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan, People's Republic of China.

Dragon's blood collected from the genus Dracaena is used as a renowned traditional medicine in various cultures worldwide. However, the genetics of the genus Dracaena and the formation mechanism of dragon's blood remain poorly understood. Here, we generate the first draft genome reference assembly of an elite Chinese Dracaena species, Dracaena cambodiana, from next-generation sequencing data with 89. Read More

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December 2018

Psychometric Evaluation of an Instrument to Measure Prospective Pregnancy Preferences: The Desire to Avoid Pregnancy Scale.

Med Care 2018 Dec 13. Epub 2018 Dec 13.

Department of Obstetrics, Gynecology and Reproductive Sciences, Bixby Center for Global Reproductive Health, Advancing New Standards in Reproductive Health (ANSIRH), University of California, San Francisco, School of Medicine, San Francisco.

Background: Existing approaches to measuring women's pregnancy intentions suffer important limitations, including retrospective assessment, overly simple categories, and a presumption that all women plan pregnancies. No psychometrically valid scales exist to prospectively measure the ranges of women's pregnancy preferences.

Materials And Methods: Using a rigorous construct modeling approach, we developed a scale to measure desire to avoid pregnancy. Read More

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December 2018
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Handshaking promotes deal-making by signaling cooperative intent.

J Pers Soc Psychol 2018 Dec 13. Epub 2018 Dec 13.

Department of Marketing, Harvard Business School.

We examine how a simple handshake-a gesture that often occurs at the outset of social interactions-can influence deal-making. Because handshakes are social rituals, they are imbued with meaning beyond their physical features. We propose that during mixed-motive interactions, a handshake is viewed as a signal of cooperative intent, increasing people's cooperative behavior and affecting deal-making outcomes. Read More

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December 2018

New recommendations for testing indirect effects in mediational models: The need to report and test component paths.

J Pers Soc Psychol 2018 Dec;115(6):929-943

Department of Psychology, University of Colorado.

In light of current concerns with replicability and reporting false-positive effects in psychology, we examine Type I errors and power associated with 2 distinct approaches for the assessment of mediation, namely the component approach (testing individual parameter estimates in the model) and the index approach (testing a single mediational index). We conduct simulations that examine both approaches and show that the most commonly used tests under the index approach risk inflated Type I errors compared with the joint-significance test inspired by the component approach. We argue that the tendency to report only a single mediational index is worrisome for this reason and also because it is often accompanied by a failure to critically examine the individual causal paths underlying the mediational model. Read More

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December 2018

Robustness and Efficiency of Poisson-Boltzmann Modeling on GPUs.

Authors:
Ruxi Qi Ray Luo

J Chem Inf Model 2018 Dec 14. Epub 2018 Dec 14.

Poisson-Boltzmann equation (PBE)-based continuum electrostatics models have been widely used in modeling electrostatic interactions in biochemical processes, particularly in estimating protein-ligand binding affinities. Fast convergence of PBE solvers is crucial in binding affinity computations as numerous snapshots need to be processed. Efforts have been reported to develop PBE solvers on graphics processing units (GPUs) for efficient modeling of biomolecules, though only relatively simple successive over-relaxation and conjugate gradient methods were implemented. Read More

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December 2018

[Efficacy of SUPRA HFR in the treatment of acute renal damage during multiple myeloma].

G Ital Nefrol 2018 Dec;35(6)

S.C. Nefrologia, Dialisi e Trapianto U. AOU Città della Salute e della Scienza di Torino, Torino, Italia.

Acute Kidney Injury (AKI) is a frequent complication of multiple myeloma (MM) with unfavorable prognostic significance. Light chains removal, combined with hematological therapy (CT) seems to offer significant benefits to renal function recovery (RFR). The SUPRA HFR, through the combination of high cut-off membrane without albumin loss and adsorbent cartridge, represents one of the "emerging" light chain removal methods. Read More

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December 2018

[Tumor hip prosthesis in fibrous dysplasia of proximal femur. Case report].

Acta Ortop Mex 2018 Jul-Aug;32(4):225-228

Unidad Médica de Alta Especialidad del Hospital de Traumatología y Ortopedia de Puebla del Instituto Mexicano del Seguro Social. Puebla, México.

Background: fibrous dysplasia is characterized by the formation of fibrous tissue that generates immature malformed trabeculae. Their involvement may be monostotic or poliostotic.

Case Report: Thirty years old female with fibrous dysplasia of the left hip. Read More

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December 2018

Effect of high frequency oscillatory high flow nasal cannula on carbon dioxide clearance in a premature infant lung model: A bench study.

Pediatr Pulmonol 2018 Dec 14. Epub 2018 Dec 14.

CHOP Newborn Care at Pennsylvania Hospital, Philadelphia, Pennsylvania.

Objective: This study compared CO clearance in a premature infant lung model connected to a high flow nasal cannula (HFNC) system supplied with oscillatory versus non-oscillatory flow.

Design/methods: The lung model was set to compliance 1.0 mL/cmH O, RR 60 breaths/min, and 6 mL tidal volume. Read More

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December 2018
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Quantifying egocentric spatial neglect with cancellation tasks: A theoretical validation.

J Neuropsychol 2018 Dec 14. Epub 2018 Dec 14.

Department of Brain and Cognition, KU Leuven, Belgium.

Spatial neglect is characterized by a spatial bias in response to stimuli. The disorder is often assessed with a cancellation task, where several measures can be used to quantify the spatial bias of cancellation responses (e.g. Read More

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December 2018

Room Temperature Synthesis of Germanium Oxide Nanofilaments and Their Potential Use as Luminescent Self-Cleaning Surfaces.

Chemphyschem 2018 Dec 14. Epub 2018 Dec 14.

University of Zurich, Winterthurerstrasse 190, 8057, Zürich, SWITZERLAND.

Germanium oxide nanofilaments (GNFs) have been synthesized under ambient conditions from the gas phase using germanium tetrachloride as a precursor. Non-crystalline GNFs synthesized by this procedure are 1-10 µm in length and 80-110 nm in diameter applying Droplet Assisted Growth and Shaping (DAGS) Chemistry. The relative humidity has been adjusted at various values in order to demonstrate the crucial role of humidity in the gas phase for the nanofilament synthesis. Read More

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December 2018

Quantitative multi-locus metabarcoding and waggle dance interpretation reveal honey bee spring foraging patterns in Midwest agroecosystems.

Mol Ecol 2018 Dec 14. Epub 2018 Dec 14.

Department of Entomology, The Ohio State University.

We explored the pollen foraging behavior of honey bee colonies situated in the corn and soybean dominated agroecosystems of central Ohio over a month-long period using both pollen metabarcoding and waggle dance inference of spatial foraging patterns. For molecular pollen analysis we developed simple and cost-effective laboratory and bioinformatics methods. Targeting four plant barcode loci (ITS2, rbcL, trnL and trnH), we implemented metabarcoding library preparation and dual-indexing protocols designed to minimize amplification biases and index mis-tagging events. Read More

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December 2018

A Mechanically Robust, Stiff, and Tough Hyperbranched Supramolecular Polymer Hydrogel.

Macromol Rapid Commun 2018 Dec 14:e1800819. Epub 2018 Dec 14.

School of Materials Science and Engineering, Tianjin Key Laboratory of Composite and Functional Materials, Tianjin University, Tianjin, 300350, China.

In this study, a simple yet versatile method is introduced to prepare a hyperbranched supramolecular polymer hydrogel by utilizing Type II photoinitiated self-condensing vinyl polymerization of N-acryloyl glycinamide, which can serve not only as an inimer providing branching sites, but also as a hydrogen-bonding cross-linker. The hyperbranched poly(N-acryloyl glycinamide) (HB-PNAGA) hydrogels demonstrate excellent mechanical performances with a tensile strength of 0.793-2. Read More

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December 2018
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Safe and easy technique for the laparoscopic application of Seprafilm® in gynecologic surgery.

Asian J Endosc Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Obstetrics and Gynecology, School of Medicine, Keio University, Tokyo, Japan.

Introduction: Laparoscopic surgery is a minimally invasive surgery, and the rate of postoperative adhesions is low. Although Seprafilm® helps to reduce adhesions, its application in the abdominal cavity during laparoscopic surgery is difficult because of its material. Therefore, we propose an easy method for applying this adhesion barrier. Read More

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December 2018

Cognitive performance in patients with implantable cardioverter defibrillators: Associations with objective sleep duration, age and anxiety.

J Sleep Res 2018 Dec 13:e12810. Epub 2018 Dec 13.

Department of Psychiatry, University of Missouri, Columbia, Missouri.

Sleep disturbance and anxiety are highly prevalent in patients with implantable cardiac defibrillators (ICDs). There is limited research, however, on the associations between cognitive performance and sleep parameters, age and anxiety. Forty-one patients with ICDs and self-reported sleep disturbance completed 14 days of actigraphy (M  = 60. Read More

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December 2018

Quantification and pharmacokinetic study of entrectinib in rat plasma using ultra-performance liquid chromatography tandem mass spectrometry.

Biomed Chromatogr 2018 Dec 13:e4467. Epub 2018 Dec 13.

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, PR China.

To characterize the preclinical plasma pharmacokinetics of entrectinib, a reproducible and precise assay is necessary. In this study, we developed and validated a simple ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method for the measurement of entrectinib using carbamazepine as the internal standard (IS) in rat plasma. Sample preparation was a simple protein precipitation with acetonitrile, then entrectinib was eluted on an Acquity UPLC BEH C18 column (2. Read More

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December 2018

Using density based indexes to characterize excited states evolution.

J Comput Chem 2018 Dec 14. Epub 2018 Dec 14.

Chimie ParisTech, PSL Research University, CNRS, Institut de Recherche de Chimie Paris, F-75005, Paris, France.

With the aim of offering new computational tools helping in the description of photochemical reactions and phenomena occurring at the excited state, we present in this work the capability of a density based index (Π) in locating decay channels from higher to lower excited states. The Π index, previously applied to disclose non-radiative decay channels from the first excited state to the ground state, is very simple in its formulation and can be evaluated, practically with no extra computational cost, and coupled to any quantum method able to provide excited states densities. Indeed, this index relies only on the knowledge of energetics and electron densities of the different electronic states involved in the decay. Read More

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December 2018

An assessment of the impact of green tea extract on palbociclib pharmacokinetics using a validated UHPLC-QTOF-MS method.

Biomed Chromatogr 2018 Dec 13:e4469. Epub 2018 Dec 13.

Drug Metabolism and Interactions Research Lab, Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, Telangana, India.

Green tea extracts (GTE) has been reported to be a kinase inhibitor and modulator for various drug metabolizing enzymes. It may give synergetic antioncogenic effect, but with a possibility of pharmacokinetic interactions with various co-administered anticancer agents like palbociclib (PAL), a selective inhibitor of CDK-4/6 primarily metabolized by CYP3A4 enzyme. To explore the impact of GTE on PAL pharmacokinetics in Sprague Dawley rats, a rapid and sensitive UHPLC-QTOF-MS method was established. Read More

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December 2018

Mandated wrapping of airway cart instruments: Limited access without the intended safety benefits.

Laryngoscope 2018 Dec 13. Epub 2018 Dec 13.

Greenville Voice Center, Greenville ENT Associates, Greenville Health System, Greenville, South Carolina, U.S.A.

Objectives/hypothesis: Isolated case studies have shown improper sterilization or contamination of equipment from anesthesia carts can lead to transmission of disease and even death. Citing this literature, national accrediting agencies mandated all instruments in the otolaryngology airway carts at San Antonio Military Medical Center be packaged to prevent contamination. This study sought to determine the infection and safety implications of packaged airway cart instruments. Read More

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December 2018

Stability and degradation products of imipenem applying High-Resolution Mass Spectrometry: an analytical study focused on solutions for infusion.

Biomed Chromatogr 2018 Dec 13:e4471. Epub 2018 Dec 13.

Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul, Porto Alegre-RS, Brazil.

Carbapenems show recognized instability in aqueous solutions, therefore some care must be taken from its handling and preparation to its use in the hospital environment. Here, the stability and degradation products of imipenem were investigated from conditions that simulate its clinical use. For this, a simple stability-indicating method by HPLC-DAD was validated with focus on quantitation of drug concentration remaining from infusion solutions (sodium chloride 0. Read More

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December 2018

Highly Regioselective Remote Lithiation of Functionalized 1,3-bis-Silylated Arenes.

Angew Chem Int Ed Engl 2018 Dec 13. Epub 2018 Dec 13.

LMU München, Department of Chemistry, Butenandtstr. 5-13, 81377, München, GERMANY.

Substituted arenes flanked by two bulky triethylsilyl groups are regiospecifically lithiated in 5-position with nBuLi•PMDTA at 25 °C. The resulting aryllithiums reacted with a broad range of electrophiles such as ketones, isocyanates, Weinreb-amides, allyl bromides or CO2 at 25 °C. These bis-silylated arenes were converted in simple reaction sequences to silyl-free tetrasubstituted arenes. Read More

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December 2018

Electrochemical Oxidative C(sp3)-H/N-H cross-coupling for N-Mannich Bases with Hydrogen Evolution.

ChemSusChem 2018 Dec 13. Epub 2018 Dec 13.

Wuhan University, Chemistry, the college of chemistry and molecular Sciences, 430072, Wuhan, CHINA.

N-Mannich bases are a kind of important structure in various functional molecules. A novel protocol to synthesize N-Mannich bases has been established through electrochemical external oxidant-free cross C(sp3)-H/N-H coupling with hydrogen evolution. Various N-methylanilines have been explored in this transformation. Read More

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December 2018
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High-Performance Photoinduced Memory with Ultrafast Charge Transfer Based on MoS /SWCNTs Network Van Der Waals Heterostructure.

Small 2018 Dec 13:e1804661. Epub 2018 Dec 13.

State Key Laboratory for Chemo/Biosensing and Chemometrics, School of Physics and Technology, Wuhan University, Wuhan, 430072, China.

Photoinduced memory devices with fast program/erase operations are crucial for modern communication technology, especially for high-throughput data storage and transfer. Although some photoinduced memories based on 2D materials have already demonstrated desirable performance, the program/erase speed is still limited to hundreds of micro-seconds. A high-speed photoinduced memory based on MoS /single-walled carbon nanotubes (SWCNTs) network mixed-dimensional van der Waals heterostructure is demonstrated here. Read More

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December 2018

Isolated Recovery of Adductor Muscle Function Following Bilateral Recurrent Laryngeal Nerve Injuries.

Laryngoscope 2018 Dec 13. Epub 2018 Dec 13.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Szeged, Szeged, Hungary.

Objectives/hypothesis: The aim of this study was to analyze the phoniatric and respiratory outcomes of a subset of bilateral vocal cord paralysis (BVCP) patients who were all treated with unilateral endoscopic arytenoid abduction lateropexy (EAAL). EAAL is a nondestructive, minimally invasive glottis widening operation, which does not damage either the surgically treated or the contralateral vocal cord. Therefore, it does not impair the regeneration potential of the recurrent laryngeal nerve. Read More

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December 2018

PLGA/PLCA casting and PLGA/PDPA electrospinning bilayer film for prevention of postoperative adhesion.

J Biomed Mater Res B Appl Biomater 2018 Dec 13. Epub 2018 Dec 13.

Sichuan Key Laboratory of Medical Imaging and Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.

Postoperative adhesion is a common complication and preventing adhesions during or immediately after operation is particularly important. The application of solid barrier materials represents the most successful clinical strategy to prevent postoperative adhesion. However, a simple physical barrier effect might be insufficient in preventing adhesion satisfactorily. Read More

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December 2018

An effective method to reduce the interplay effects between respiratory motion and a uniform scanning proton beam irradiation for liver tumors: A case study.

J Appl Clin Med Phys 2018 Dec 13. Epub 2018 Dec 13.

Department of Radiation Oncology, New York University Langone Medical Center, Laura and Isaac, Perlmutter Cancer Center, New York, NY, USA.

Purpose: For scanning particle beam therapy, interference between scanning patterns and interfield organ motion may result in suboptimal dose within target volume. In this study, we developed a simple offline correction technique for uniform scanning proton beam (USPB) delivery to compensate for the interplay between scanning patterns and respiratory motion and demonstrate the effectiveness of our technique in treating liver cancer.

Methods: The computed tomography (CT) and respiration data of two patients who had received stereotactic body radiotherapy for hepatocellular carcinoma were used. Read More

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December 2018

A molecularly imprinted polymer based chemiluminescence array sensor for one-step determination of phenothiazines and benzodiazepines in pig urine.

Luminescence 2018 Dec 12. Epub 2018 Dec 12.

College of Veterinary Medicine, Hebei Agricultural University, Baoding, Hebei, China.

The residues of phenothiazines and benzodiazepines in foods of animal origin are dangerous to consumers. For inspection of their abuses, this study for the first time reported on the use of a chemiluminescence array sensor for the simultaneous determination of four phenothiazines and five benzodiazepines in pig urine. Two molecularly imprinted polymers were coated in different wells of a conventional 96-well microtiter plate as the recognition reagents. Read More

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December 2018

Metabolic Rhythms: a framework for coordinating cellular function.

Authors:
Helen C Causton

Eur J Neurosci 2018 Dec 13. Epub 2018 Dec 13.

Dept. of Pathology and Cell Biology, Columbia University Medical Center, New York, NY10032, USA.

Circadian clocks are widespread among eukaryotes and generally involve feedback loops coupled with metabolic processes and redox balance. The organising power of these oscillations has not only allowed organisms to anticipate day-night cycles, but also acts to temporally compartmentalise otherwise incompatible processes, enhance metabolic efficiency, make the system more robust to noise and propagate signals among cells. While daily rhythms and the function of the circadian transcription-translation loop have been the subject of extensive research over the past four decades, cycles of shorter period and respiratory oscillations, with which they are intertwined, have received less attention. Read More

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December 2018

A fast scheme to calculate electronic couplings between P3HT polymer units using diabatic orbitals for charge transfer dynamics simulations.

J Comput Chem 2019 Jan;40(2):532-542

Center of Nanophase Materials Sciences & Computational Sciences and Engineering Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, 37831.

We propose a fast and accurate calculation method to compute the electronic couplings between molecular units in a thiophene-ring-based polymer chain mimicking a real organic semiconducting polymer, poly(3-hexylthiophene). Through a unit block diabatization scheme, the method employed minimal number of diabatic orbitals to compute the site energies and electronic couplings, which were validated by comparing with benchmark density functional theory calculations. In addition, by using the obtained electronic couplings, a quantum dynamics simulation was carried out to propagate a hole initially localized in a thiophene-ring unit of the polymer chain. Read More

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January 2019

Tissue-based transcriptomics of Chionodraco hamatus: sequencing, de novo assembly, annotation and marker discovery.

J Fish Biol 2018 Dec 13. Epub 2018 Dec 13.

Key Laboratory of East China Sea and Oceanic Fishery Resources Exploitation, Ministry of Agriculture, East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai, China.

Here, we explored the liver, heart and muscle tissue transcriptome of the haemoglobinless Antarctic fish Chionodraco hamatus using the Illumina paired-end RNA sequencing. A total of 114,028 unigenes with a mean length of 794.24 bp was produced. Read More

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December 2018

Integrating molecular networks with genetic variant interpretation for precision medicine.

Wiley Interdiscip Rev Syst Biol Med 2018 Dec 12:e1443. Epub 2018 Dec 12.

Department of Medicine and Institute for Genomic Medicine, University of California, San Diego, La Jolla, California.

More reliable and cheaper sequencing technologies have revealed the vast mutational landscapes characteristic of many phenotypes. The analysis of such genetic variants has led to successful identification of altered proteins underlying many Mendelian disorders. Nevertheless the simple one-variant one-phenotype model valid for many monogenic diseases does not capture the complexity of polygenic traits and disorders. Read More

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December 2018

Isothiourea-Catalyzed Regioselective Acylative Kinetic Resolution of Axially Chiral Biaryl Diols.

Chemistry 2018 Dec 12. Epub 2018 Dec 12.

University of St Andrews, School of Chemistry, North Haugh, KY16 9ST, St. Andrews, UNITED KINGDOM.

An operationally-simple isothiourea-catalyzed acylative kinetic resolution of unprotected 1,1'-biaryl-2,2'-diol derivatives has been developed to allow access to axially chiral compounds in highly enantioenriched form (s values up to 190). Investigation of the reaction scope and limitations provided three key observations: i) the diol motif of the substrate was essential for good conversion and high s values; ii) the use of an α,α-disubstituted mixed anhydride (2,2-diphenylacetic pivalic anhydride) was critical to minimize diacylation and give high selectivity; iii) the presence of substituents in the 3,3'-positions of the diol hindered effective acylation. This final observation was exploited for the highly regioselective acylative kinetic resolution of unsymmetrical biaryl diol substrates bearing a single 3-substituent. Read More

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December 2018

Z-scores of the fetal trachea and bronchial dimension.

Prenat Diagn 2018 Dec 12. Epub 2018 Dec 12.

Department of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.

Objective: To develop Z-scores for the trachea and main bronchi in normal fetuses.

Methods: This was a prospective cross-sectional study in 823 normal singleton fetuses. The tracheal diameter immediately proximal to the bifurcation as well as the left and right main bronchial diameters were measured from their inner to inner edge in the coronal view. Read More

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December 2018

"Interpenetration Isomerism" of Triptycene-Based Hydrogen-Bonded Organic Frameworks.

Angew Chem Int Ed Engl 2018 Dec 11. Epub 2018 Dec 11.

Northwestern University, Department of Chemistry, 2145 Sheridan Road, 60208-3113, EVANSTON, UNITED STATES.

We describe an example of "interpenetration isomerism" in three-dimensional (3D) hydrogen-bonded organic frameworks (HOFs). By exploiting the crystallization conditions for a peripherally extended triptycene H6PET, we can modulate the interpenetration of the assembled frameworks, yielding a two-fold interpenetrated structure PETHOF-1 (acs-2c topology) and a five-fold interpenetrated structure PETHOF-2 (acs-5c topology) as "interpenetration isomers". In PETHOF-1, two individual nets are related by inversion symmetry and form an interwoven topology with a strikingly large guest-accessible volume of about 80%. Read More

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December 2018

Getting into shape: Limb bone strength in perinatal Lemur catta and Propithecus coquereli.

Anat Rec (Hoboken) 2018 Dec 8. Epub 2018 Dec 8.

School of Physical Therapy, Slippery Rock University, Slippery Rock, PA, 16057.

Functional studies of skeletal anatomy are predicated on the fundamental assumption that form will follow function. For instance, previous studies have shown that the femora of specialized leaping primates are more robust than those of more generalized primate quadrupeds. Are such differences solely a plastic response to differential loading patterns during postnatal life, or might they also reflect more canalized developmental mechanisms present at birth? Here, we show that perinatal Lemur catta, an arboreal/terrestrial quadruped, have absolutely and relatively weaker femora than perinatal Propithecus coquereli, a closely-related species specialized for vertical clinging and leaping (a highly unusual locomotor mode in which the hindlimbs are used to launch the animal between vertical tree trunks). Read More

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December 2018

3D Gold-Modified Cerium and Cobalt Oxide Catalyst on a Graphene Aerogel for Highly Efficient Catalytic Formaldehyde Oxidation.

Small 2018 Dec 7:e1804415. Epub 2018 Dec 7.

Collaborative Innovation Center of Suzhou Nano Science and Technology, College of Chemistry, Chemical Engineering and Materials ScienceSoochow University, 199 Ren'ai Road, Suzhou, 215123, P.R. China.

A hard template method is used to prepare porous gold-doped cerium and cobalt oxide (Au-Ce Co ) materials. A series of 3D Au-Ce Co /graphene aerogel (GA) composites is then fabricated by a facile heating method. The obtained catalysts possess a well-defined structure of ordered arrays of nanotubes and good performance in formaldehyde (HCHO) oxidation. Read More

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December 2018

Visceral Adiposity Index is not Superior over Anthropometric Parameters with regards to Inflammation in Healthy Adolescent Girls.

P R Health Sci J 2018 Dec;37(4):195-199

Department of Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.

Objective: Better than simple anthropometric parameters, the visceral adiposity index (VAI) has recently been proposed as a predictor of cardiometabolic risk in adults. However, there are conflicting results on the associations of these parameters in children and adolescents. Therefore, we aimed to estimate this potential relationship between VAI, anthropometric parameters (i. Read More

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December 2018
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