Eur J Case Rep Intern Med 2021 29;8(11):002983. Epub 2021 Nov 29.
Hematology/Oncology Division, Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States.
Introduction: Copper deficiency or hypocupraemia is a rare cause of anaemia and neutropenia.
Case Description: We hereby present the case of a 34-year-old female with gastric bypass surgery who presented with neutropenic fever, abdominal pain and diarrhoea, later found to have extended-spectrum beta-lactamase resistant urinary tract infection and small bowel bacterial overgrowth syndrome, with her anaemia and neutropenia being caused by copper deficiency due to hyperzincaemia induced by using zinc denture adhesive cream.
Discussion: Various causes of copper deficiency have been recognized including, but not limited to, malnutrition, gastrectomy, gastric bypass surgery, protein-losing enteropathies (coeliac disease, tropical sprue), Wilson disease and Menkes syndrome. Read More