5,807 results match your criteria Shock and Pregnancy


The efficacy of pivmecillinam in oral step-down treatment in hospitalised patients with E. coli bacteremic urinary tract infection; a single-arm, uncontrolled treatment study.

BMC Infect Dis 2022 May 19;22(1):478. Epub 2022 May 19.

Department of Infectious Diseases, Vestfold Hospital Trust, Postbox 2168, 3103, Tønsberg, Norway.

Background: The role of oral beta-lactam antibiotics in treating febrile urinary tract infections (UTI) is not yet definite. Today, fluoroquinolones together with trimethoprim-sulfamethoxazole (TMP-MTX) are considered standard of care and often the only available evidence-based oral treatment for febrile UTI. This study clarifies the efficacy and safety of pivmecillinam (PIV) used as step-down therapy for bacteremic urinary tract infection (UTI). Read More

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Hemorrhagic shock due to colonic arteriovenous malformation in late pregnancy: a case report.

Int J Emerg Med 2022 May 17;15(1):20. Epub 2022 May 17.

Interventional Radiology Center, Teikyo University Chiba Medical Center, 3426-3 Anesaki, Ichihara, Chiba, 299-0111, Japan.

Background: Intestinal arteriovenous malformations are difficult to detect because they often present asymptomatically. However, pregnancy increases the hemorrhagic risk of intestinal arteriovenous malformations. This can lead to massive bleeding and hemodynamic instability, threatening the lives of both the mother and fetus. Read More

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Adverse Effects of High Temperature On Mammary Alveolar Development In Vitro.

J Mammary Gland Biol Neoplasia 2022 May 17. Epub 2022 May 17.

Laboratory of Cell and Tissue Biology, Research Faculty of Agriculture, Hokkaido University, North 9, West 9, 060-8589, Sapporo, Japan.

In the mammary glands during pregnancy, the alveolar buds are first branched from the mammary ducts after which they form the alveolar luminal structure for milk production postparturition. Body temperature could increase for several reasons, such as infectious disease and heat stress. We have previously reported that high temperature adversely effects on the lactation capacity of mouse mammary epithelial cells (MECs). Read More

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Urolithiasis in pregnancy: Advances in imaging modalities and evaluation of current trends in endourological approaches.

Actas Urol Esp (Engl Ed) 2022 May 9. Epub 2022 May 9.

Department of Urology, Louisiana State University Health Sciences Center, Shreveport, USA. Electronic address:

Objective: Given the challenges involved in diagnosis and treatment of pregnant women with urolithiasis, we aim to review the imaging modalities and current endourological management of these patients.

Materials And Methods: We performed a review of the available literature on urolithiasis in pregnancy. This included evaluation, diagnostic imaging, and therapeutic options. Read More

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Massive maternal haemorrhage due to a mandibular arteriovenous malformation in a term pregnancy: A case report.

Case Rep Womens Health 2022 Apr 28;34:e00418. Epub 2022 Apr 28.

Royal Prince Alfred Hospital, Women and Babies Department, Sydney, Australia.

Mandibular arteriovenous malformations (AVMs) are vascular lesions that are rare in pregnancy but that can be life threatening due to the potential for massive haemorrhage when ruptured. This report describes a 30-year-old woman who presented at 39 weeks of gestation with hypovolemic shock secondary to a massive haemorrhage from her oral cavity. After resuscitation, she underwent an emergency caesarean section indicated for fetal distress. Read More

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Hepatic Infarction in a Patient With Sickle Cell Trait Presenting With HELLP Syndrome.

Cureus 2022 Apr 1;14(4):e23724. Epub 2022 Apr 1.

Internal Medicine, Manipal College of Medical Sciences, Pokhara, NPL.

Hepatic infarction is uncommon due to the dual blood supply from the hepatic artery and portal vein. The majority of the cases are caused following liver transplant or hepatobiliary surgery, hepatic artery occlusion, or shock. Hepatic infarction is a rare complication of hemolysis, elevated liver enzymes, and low platelet (HELLP) syndrome. Read More

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Multidisciplinary Simulation Improves Resident Confidence for Pregnant Patients Requiring Surgical Intervention.

Cureus 2022 Mar 24;14(3):e23454. Epub 2022 Mar 24.

Simulation, Riverside Methodist Hospital/OhioHealth, Columbus, USA.

Introduction: Hepatocellular adenomas are a rare but serious cause of bleeding, which is further complicated by pregnancy. Interprofessional cooperation is a key component of residency education, thus simulations designed to integrate multiple programs are mutually beneficial. This simulation details surgical and obstetric management of a pregnant patient in hemorrhagic shock from a bleeding hepatocellular adenoma. Read More

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Sudden respiratory and circulatory collapse after cesarean section: Amniotic fluid embolism or other reasons? - a case report.

BMC Pregnancy Childbirth 2022 Apr 28;22(1):369. Epub 2022 Apr 28.

Department of Anesthesiology, West China Second University Hospital; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Ministry of Education), Sichuan University, Chengdu, China.

Background: For a healthy parturient, a cardiopulmonary collapse that suddenly occurs shortly after an uneventful caesarean section is a relatively rare event and presents a significant challenge for the anesthesia provider.

Case Presentation: Amniotic fluid embolism (AFE) is characterized by acute and rapid collapse and is well known to the obstetric team. Our patient experienced sudden cardiovascular collapse, severe respiratory difficulty and hypoxia, in the absence of other explanations for these findings at the time, and thus AFE was immediately become the focus of the consideration. Read More

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infection in a pregnant woman: a case report.

Curr Med Res Opin 2022 May 13:1-4. Epub 2022 May 13.

Department of Gynecology, The Third People's Hospital of Qingdao, Qingdao, China.

Background: belongs is a gram-positive anaerobic coccus (GPAC), which can cause bacterial vaginitis. However, only a few studies have reported severe infection of . This study presented the first case of severe infection of during pregnancy. Read More

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Case Report: Fatal Outcome for a Preterm Newborn With Meningitis Caused by Extended-Spectrum β-Lactamase-Producing Sequence Type 1193.

Front Pediatr 2022 6;10:866762. Epub 2022 Apr 6.

Department of Neonatology, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.

Introduction: In this case report, we describe an extended-spectrum beta-lactamase (ESBL) - strain of sequence type (ST) 1193, a novel, virulent, multidrug-resistant (MDR) clone with a rapid global spread. ST 1193 has been more commonly associated with invasive disease than other ESBL- STs. To our knowledge, this is the first known case in Sweden where a newborn died of an ESBL- ST 1193 meningitis. Read More

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Placenta percreta as a cause of uterine rupture in the second trimester: Case report.

Int J Surg Case Rep 2022 Apr 11;94:107069. Epub 2022 Apr 11.

Department of Gynecology and Obstetrics, Maternity of Souissi, Faculty of Medicine, Mohamed V Souissi University, Rabat, Morocco.

Introduction: Placenta accreta spectrum is a very life-threatening obstetrical condition whose rate increased significantly the past years due to the increase of caesarean deliveries. In some rare cases, it can cause uterine rupture which needs to be diagnosed and managed quickly to avoid catastrophic outcomes.

Case Report: We present a case of a 33-year-old patient who was admitted to the emergency room for signs of shock at 29 weeks of a poorly supervised pregnancy, secondary to a spontaneous uterine rupture on a previously scarred uterus by a caesarean delivery two years prior to the events. Read More

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Artesunate Resistance - An Emerging Threat.

J Assoc Physicians India 2022 Apr;70(4):11-12

Kalinga Institute of Medical Sciences, Khorda.

Drug resistant malaria represents a challenging health problem in developing countries like India. The failure of drug artemisinin, which is the cornerstone of malaria therapy will rapidly compromise the treatment and prognosis of malaria. Resistance should be suspected if inspite of full treatment with Artesunate Combination Therapy and with no history of vomiting or diarrhoea, there is no clinical or parasitological response in the patient after 72 hours. Read More

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Omphalitis and Concurrent Serious Bacterial Infection.

Pediatrics 2022 05;149(5)

Department of Pediatrics, Saint Louis University School of Medicine, St. Louise, Missouri.

Objective: Describe the clinical presentation, prevalence of concurrent serious bacterial infection (SBI), and outcomes among infants with omphalitis.

Methods: Within the Pediatric Emergency Medicine Collaborative Research Committee, 28 sites reviewed records of infants ≤90 days of age with omphalitis seen in the emergency department from January 1, 2008, to December 31, 2017. Demographic, clinical, laboratory, treatment, and outcome data were summarized. Read More

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The effect of subdiaphragmatic vagotomy on heart rate variability and lung inflammation in rats with severe hemorrhagic shock.

BMC Cardiovasc Disord 2022 04 19;22(1):181. Epub 2022 Apr 19.

Department of Biology, College of Sciences, Shiraz University, Shiraz, Iran.

Background: The influence of cutting the sub-diaphragmatic branch of the vagus nerve on heart rate variability (HRV) and inflammatory reaction to severe hemorrhagic shock has not been determined prior to this study.

Methods: Male Sprague-Dawley rats were divided into four groups of Sham, sub-diaphragmatic vagotomized (Vag), subacute (135 ± 2 min) hemorrhagic shock (SHS), and sub-diaphragmatic vagotomized with SHS (Vag + SHS). Hemodynamic parameters were recorded and HRV calculated during multiple phases in a conscious model of hemorrhagic shock. Read More

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Upper Gastrointestinal Bleeding in Pregnancy: An Unexpected Cause.

J Emerg Trauma Shock 2022 Jan-Mar;15(1):72-73. Epub 2022 Apr 4.

Department of Emergency Medicine, Dr. D. Y. Patil Medical College, Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra, India.

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Impact of heat stress on milk yield, antioxidative levels, and serum metabolites in primiparous and multiparous Holstein cows.

Trop Anim Health Prod 2022 Apr 14;54(3):159. Epub 2022 Apr 14.

Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Jilin Agricultural University, Changchun, 130118, People's Republic of China.

This study aimed to access the effect of heat stress on milk yield, antioxidative levels, and serum metabolites in primiparous and multiparous Holstein dairy cows during the early lactation stage. A total of 200 cows were selected based on their month of calving (June, temperature humidity index (THI) = 66.72; July, THI = 70. Read More

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Panaxytriol upregulates CYP3A4 expression based on the interaction of PXR, CAR, HSP90α, and RXRα.

Phytomedicine 2022 Jul 6;101:154097. Epub 2022 Apr 6.

Clinical Pharmacology Institute, Nanchang University, Bayi Road 461, Nanchang 330006, PR China. Electronic address:

Background: Cytochrome P450 3A4 (CYP3A4) is one of the most important drug-metabolizing enzymes in the human body, mainly existing in the liver, small intestine, and kidney. Panaxytriol is one of the key active components in red ginseng and Shenmai injection. Our previous study demonstrated that panaxytriol regulates CYP3A4 expression mainly by activating pregnancy X receptor (PXR). Read More

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Clinical algorithms for the management of intrapartum maternal urine abnormalities.

BJOG 2022 Apr 12. Epub 2022 Apr 12.

The Fetal Medicine Centre, Birmingham Women's and Children's Foundation Trust, Edgbaston, Birmingham, B15 2TG, UK.

Aim: To develop evidence-based clinical algorithms for management of common intrapartum urinary abnormalities.

Population: Women with singleton, term pregnancies in active labour and immediate postnatal period, at low risk of complications.

Setting: Healthcare facilities in low- and middle-income countries. Read More

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Low peripheral perfusion index values may indicate the need for antivenom in the early phase of scorpion envenomation.

Am J Emerg Med 2022 Jun 31;56:104-106. Epub 2022 Mar 31.

Adnan Menderes University Hospital Department of Emergency Medicine, Efeler, Aydın, Turkey.

Background: Scorpion envenomation may cause local symptoms as well as life-threatening situations including shock, and death. Antivenom administration is the cornerstone of therapy, meticulous patient selection is needed because of the possible side effects of the antivenom including anaphylaxis. Peripheral perfusion index (PPI) is a simple, non-invasive test that is widely used for the detection of peripheral hypoperfusion. Read More

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Ruptured uterus: Frequency, risk factors and feto-maternal outcome: Current scenario in a low-resource setup.

PLoS One 2022 8;17(4):e0266062. Epub 2022 Apr 8.

Department of Pain Clinic, Shifa International Hospital, Islamabad, Pakistan.

Introduction: Pakistan is among the countries with the highest maternal death rates. Obstetric hemorrhage accounts for 41% of these deaths. Uterine rupture is a grave obstetric emergency with high maternal and neonatal morbidity and mortality. Read More

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Amniotic fluid embolism rescued by venoarterial extracorporeal membrane oxygenation.

Crit Care 2022 04 7;26(1):96. Epub 2022 Apr 7.

Service de Médecine Intensive-Réanimation, Institut de Cardiologie, APHP Sorbonne Université Hôpital Pitié-Salpêtrière, 75013, Paris, France.

Background: Amniotic fluid embolism (AFE) is a rare but often catastrophic complication of pregnancy that leads to cardiopulmonary dysfunction and severe disseminated intravascular coagulopathy (DIC). Although few case reports have reported successful use of venoarterial extracorporeal membrane oxygenation (VA-ECMO) with AFE, concerns can be raised about the increased bleeding risks with that device.

Methods: This study included patients with AFE rescued by VA-ECMO hospitalized in two high ECMO volume centers between August 2008 and February 2021. Read More

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Invasive group A streptococcal disease in pregnant women and young children: a systematic review and meta-analysis.

Lancet Infect Dis 2022 Apr 4. Epub 2022 Apr 4.

Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.

Background: The incidence of invasive disease caused by group A streptococcus (GAS) has increased in multiple countries in the past 15 years. However, despite these reports, to the best of our knowledge, no systematic reviews and combined estimates of the incidence of invasive GAS have been done in key high-risk groups. To address this, we estimated the incidence of invasive GAS disease, including death and disability outcomes, among two high-risk groups-namely, pregnant women and children younger than 5 years. Read More

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2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

J Am Coll Cardiol 2022 05 1;79(17):1757-1780. Epub 2022 Apr 1.

Aim: The "2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure" replaces the "2013 ACCF/AHA Guideline for the Management of Heart Failure" and the "2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure." The 2022 guideline is intended to provide patient-centric recommendations for clinicians to prevent, diagnose, and manage patients with heart failure.

Methods: A comprehensive literature search was conducted from May 2020 to December 2020, encompassing studies, reviews, and other evidence conducted on human subjects that were published in English from MEDLINE (PubMed), EMBASE, the Cochrane Collaboration, the Agency for Healthcare Research and Quality, and other relevant databases. Read More

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2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

J Am Coll Cardiol 2022 05 1;79(17):e263-e421. Epub 2022 Apr 1.

Aim: The "2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure" replaces the "2013 ACCF/AHA Guideline for the Management of Heart Failure" and the "2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure." The 2022 guideline is intended to provide patient-centric recommendations for clinicians to prevent, diagnose, and manage patients with heart failure.

Methods: A comprehensive literature search was conducted from May 2020 to December 2020, encompassing studies, reviews, and other evidence conducted on human subjects that were published in English from MEDLINE (PubMed), EMBASE, the Cochrane Collaboration, the Agency for Healthcare Research and Quality, and other relevant databases. Read More

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Clinical Effect of Nimodipine Combined with Magnesium Sulfate on Pregnancy-Induced Hypertension Syndrome.

J Healthc Eng 2022 25;2022:7217543. Epub 2022 Mar 25.

Department of Reproduction and Genetics, Heping Hospital Affiliated to Changzhi Medical College, Changzhi 046000, China.

The incidence of pregnancy-induced hypertension in China is 9.4%, which is at a relatively high level. Its serious impact on maternal and infant health is the main reason for maternal and perinatal morbidity and mortality. Read More

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2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

Circulation 2022 May 1;145(18):e876-e894. Epub 2022 Apr 1.

ACC/AHA Representative.

Aim: The "2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure" replaces the "2013 ACCF/AHA Guideline for the Management of Heart Failure" and the "2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure." The 2022 guideline is intended to provide patient-centric recommendations for clinicians to prevent, diagnose, and manage patients with heart failure.

Methods: A comprehensive literature search was conducted from May 2020 to December 2020, encompassing studies, reviews, and other evidence conducted on human subjects that were published in English from MEDLINE (PubMed), EMBASE, the Cochrane Collaboration, the Agency for Healthcare Research and Quality, and other relevant databases. Read More

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2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

Circulation 2022 May 1;145(18):e895-e1032. Epub 2022 Apr 1.

ACC/AHA Representative.

Aim: The "2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure" replaces the "2013 ACCF/AHA Guideline for the Management of Heart Failure" and the "2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure." The 2022 guideline is intended to provide patient-centric recommendations for clinicians to prevent, diagnose, and manage patients with heart failure.

Methods: A comprehensive literature search was conducted from May 2020 to December 2020, encompassing studies, reviews, and other evidence conducted on human subjects that were published in English from MEDLINE (PubMed), EMBASE, the Cochrane Collaboration, the Agency for Healthcare Research and Quality, and other relevant databases. Read More

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Vitamin B12 reduces the negative effects of nicotine on fetal bone development in the rats.

Jt Dis Relat Surg 2022 28;33(1):216-224. Epub 2022 Mar 28.

Kayseri Şehir Eğitim ve Araştırma Hastanesi, Ortopedi ve Travmatoloji Kliniği, 38080 Kocasinan, Kayseri, Türkiye.

Objectives: The aim of this experimental rat study was to investigate the effectiveness of vitamin B (Vit-B) against the teratogenic effects of nicotine use during pregnancy in the fetus.

Materials And Methods: Eighteen Wistar-Albino pregnant rats were divided into six groups (n=3, each) as Group 1 (control), Group 2 (Vit-B), Group 3 (nicotine 3 mg/kg/day), Group 4 (nicotine 3 mg/kg/day + Vit-B), Group 5 (nicotine 6 mg/kg/day) and Group 6 (nicotine 6 mg/kg/day + Vit-B). Nicotine was administered subcutaneously and Vit-B was administered intraperitoneally for 20 days. Read More

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Therapeutic Hypothermia for Neonatal Encephalopathy in Low- and Middle-Income Countries: A Meta-Analysis.

Neonatology 2022 25;119(3):300-310. Epub 2022 Mar 25.

Sanjay Gandhi PGIMS, Lucknow, India.

Background: Perinatal asphyxia and hypoxic-ischemic encephalopathy (HIE) represent substantial sources of neonatal morbidity and mortality in low- and middle-income countries (LMICs), leading to high rates of adverse long-term neurological outcomes.

Methods: A systematic review with meta-analysis of randomized controlled trials in LMICs was conducted. PubMed, Scopus, Web of Science, CENTRAL, ClinicalTrials. Read More

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Success of the Cytokine Absorption Therapies in COVID-19 Patients Diagnosed with Cytokine Release Syndrome.

J Coll Physicians Surg Pak 2022 Apr;32(4):451-454

Department of Anesthesiology and Reanimation, Intensive Care Unit, University of Health Sciences, Izmir Bozyaka Training and Research Hospital, Izmir, Turkey.

Objective: To compare the effects of cytokine absorption therapy with a resin-based cytokine absorption cartridge to tocilizumab treatment in critically ill COVID-19 patients diagnosed with cytokine release syndrome (CRS).

Study Design: A descriptive study.

Place And Duration Of Study: University of Health Sciences, Izmir Bozyaka Training and Research Hospital, Izmir, Turkey from April 2020 to April 2021. Read More

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