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    Suspected atypical haemolytic uraemic syndrome in two post-partum patients with foetal-death in utero responding to eculizumab.
    Nephrology (Carlton) 2017 Feb;22 Suppl 1:18-22
    Department of Nephrology, Austin Hospital, Victoria, Australia.
    Background: Atypical haemolytic uraemic syndrome (aHUS) is a rare condition with the triad of microangiopathic haemolytic anaemia, thrombocytopenia and acute kidney injury. Other conditions that present in a similar manner peri-partum include thrombotic thrombocytopaenic purpura, and pregnancy associated conditions including HELLP syndrome (haemolysis, elevated liver enzymes and low platelets), severe pre-eclampsia and less commonly acute fatty liver of pregnancy.

    Case Reports: We describe two cases of suspected aHUS, who presented post-partum with foetal death-in-utero at 33 and 37 weeks respectively. Read More

    Maternal Type 1 diabetes activates stress response in early placenta.
    Placenta 2017 Feb 16;50:110-116. Epub 2017 Jan 16.
    Department of Obstetrics and Gynecology, Medical University of Graz, Austria. Electronic address:
    Introduction: Human pregnancy and in particular the first trimester, is a period highly susceptible towards adverse insults such as oxidative stress, which may lead to inadequate embryonic and feto-placental development. Diabetes mellitus is associated with increased oxidative stress caused by hyperglycemia, reactive oxygen species (ROS) production and inflammatory signals. In pregnancy, diabetes elevates the risk for early pregnancy loss, preeclampsia and fetal growth restriction, pathologies that origin from early placental maldevelopment. Read More

    A rare case of dengue encephalopathy complicating a term pregnancy.
    BMC Res Notes 2017 Feb 2;10(1):79. Epub 2017 Feb 2.
    Sri Jayewardenepura General Hospital, Sri Jayewardenepura, Kotte, Sri Lanka.
    Background: Dengue fever has an expanded clinical spectrum ranging from an asymptomatic infection to life threatening dengue hemorrhagic fever and refractory shock. Dengue infection in pregnancy can be a diagnostic dilemma, particularly considering the physiological changes in pregnancy and the obstetric complications encountered in clinical practice. Hence the knowledge of its diagnosis and management in its atypical presentations is of paramount importance. Read More

    [Dying at Life's Beginning].
    Gesundheitswesen 2017 Jan 27. Epub 2017 Jan 27.
    Zürcher Hochschule für Angewandte Wissenschaften, Gesundheit, Winterthur, Switzerland.
    Aim: When parents-to-be are faced with a terminal prenatal diagnosis, they are confronted with the decision either to continue the pregnancy or to terminate it at an advanced stage. This difficult decision is intimately affected by the experience of the inevitability of loss, and ethical dilemmas posed in this usually completely unexpected situation. Studies indicate that perinatal child loss due to lethal foetal anomalies is a major life event and a source of serious psychological issues, which can last for many years after the experience. Read More

    SIRT1 inhibits releases of HMGB1 and HSP70 from human umbilical vein endothelial cells caused by IL-6 and the serum from a preeclampsia patient and protects the cells from death.
    Biomed Pharmacother 2017 Jan 22;88:449-458. Epub 2017 Jan 22.
    Department of Obstetrics and Gynecology, The Affiliated Maternity and Child Health Hospital of Nanjing Medical University, Wuxi, Jiangsu Province 214002, China.
    Preeclampsia (PE), a pregnancy-specific disorder, is associated with inappropriate maternal inflammatory response, oxidative stress, and vascular endothelial cell dysfunction and damage. Releases of high mobility group box-1 (HMGB1) and heat-shock protein 70 (HSP70) into serum are considered to participate in the pathogenesis of PE. The deacetylase, sirtuin 1 (SIRT1), has protective effects against inflammation, apoptosis, and oxidative stress in various pathological conditions. Read More

    [Effect of heat exposure in the second trimester of pregnancy on intrauterine growth of fatal rat and the expression of HSP70, Bax and Bcl-2 of placenta].
    Nan Fang Yi Ke Da Xue Xue Bao 2017 Jan;37(1):89-92
    Medical College of Nanchang University, Nanchang 330006, China.E-mail:
    Objective: To investigate the effect of heat exposure during the second week of pregnancy on placental development and intrauterine growth of fetal rats.

    Methods: 24 pregnant rats were either exposed or not to a temperature of 35∓1 degrees celsius; during the second week of pregnancy. The body weight gain of the pregnant rats was measured regularly, and in late pregnancy, the pregnant rats were dissected and the number, weight, length, tail length, appearance of the offspring rats, number of live and still births, and the placental weight were recorded. Read More

    Factors associated with maternal death in an intensive care unit.
    Rev Bras Ter Intensiva 2016 Oct-Dec;28(4):397-404
    Programa de Pós-Graduação em Saúde Coletiva, Universidade de Fortaleza - Fortaleza (CE), Brasil.
    Objective:: To identify factors associated with maternal death in patients admitted to an intensive care unit.

    Methods:: A cross-sectional study was conducted in a maternal intensive care unit. All medical records of patients admitted from January 2012 to December 2014 were reviewed. Read More

    Gastric Rupture in Pregnancy: Case Series from a Tertiary Institution in Rwanda and Review of the Literature.
    AJP Rep 2016 Oct;6(4):e436-e441
    Department of Obstetrics and Gynecology, University of Rwanda, Rwanda; Department of Obstetrics and Gynecology, Duke University, Durham, North Carolina; Department of Obstetrics and Gynecology, Yale University, New Heaven, Connecticut.
    Background Gastric rupture is a rare, life-threatening condition during pregnancy. Case study We present three cases of gastric perforation during pregnancy and the puerperium. The first patient presented with gastric perforation 4 days following an uncomplicated cesarean delivery for obstetric indications. Read More

    Spontaneous rupture of renal angiomyolipoma during pregnancy.
    BMJ Case Rep 2017 Jan 6;2017. Epub 2017 Jan 6.
    Department of Obstetrics and Gynecology, University of Yamanashi, Chuo, Yamanashi, Japan.
    A renal angiomyolipoma (AML) is a rare benign tumour of kidney origin. Pregnancy is known to be associated with an increased risk of tumour rupture causing hypovolaemic shock, which is usually managed surgically or through an embolisation procedure. However, having surgery during pregnancy predisposes the mother to a preterm delivery, and the unknown influences of radiation exposure to the fetus make the management of such cases very challenging. Read More

    Primary Abdominal Pregnancy: A Case Report.
    J Clin Diagn Res 2016 Nov 1;10(11):QD04-QD06. Epub 2016 Nov 1.
    Senior Resident, Department of Obstetrics and Gynaecology, GMCH , Sector 32, Chandigarh, India .
    Abdominal pregnancy is a potentially life threatening form of ectopic gestation with an incidence of 1% of all the ectopic pregnancies. Rarely, it may reach at advanced gestation and a viable fetal outcome is indeed a rare event. Most of them are terminated earlier due to poor fetal prognosis and higher chances of maternal mortality secondary to haemorrhagic shock following spontanous placental separation. Read More

    An Unusual Cause of Postabortal Fever Requiring Prompt Surgical Intervention: A Pyomyoma and its Imaging Features.
    Oman Med J 2017 Jan;32(1):73-76
    Radiodiagnosis, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
    Pyomyoma is an unusual complication of leiomyoma, occurring most commonly in the postpartum, postabortal, and post-menopausal periods. It develops due to infection in necrotic foci within leiomyoma, which is more common during pregnancy due to rapid growth, and in postmenopausal women due to vascular insufficiency. Other contributing factors are curettage, gynecological surgery, cervical stenosis, immunodeficiency, and recently, uterine artery embolization. Read More

    Cholesterol-loaded cyclodextrin improves ram sperm cryoresistance in skim milk-extender.
    Anim Reprod Sci 2017 Feb 1;177:1-11. Epub 2016 Dec 1.
    Centre de Recherche en Reproduction, Développement et Santé Intergénérationnelle, Département des Sciences Animales, Université Laval, Québec, QC G1V 0A6, Canada. Electronic address:
    Cholesterol-loaded cyclodextrin (CLC) is known to improve ram sperm cryosurvival. This study expands on previous research to: (1) determine the mechanism by which CLC improves ram sperm cryosurvival and (2) compare the efficiency of a novel, skim milk-based extender containing CLC to a traditional egg yolk-based extender. Hypothesis #1 was that CLC enhances membrane cholesterol content to increase the resistance of ram sperm to cold and osmotic stress, thereby improving cryosurvival. Read More

    A Case of Refractory Systemic Capillary Leak Syndrome (Clarkson's Disease) during Pregnancy.
    Acta Med Okayama 2016 Dec;70(6):497-501
    Department of Anesthesiology and Resuscitology, Okayama University Hospital, Okayama 700-8558,
    A 32-year-old woman, pregnant with twins, presented with a chief complaint of general fatigue. Her general condition had rapidly deteriorated since her last visit to the primary obstetrician; the patient was then referred to our hospital because of suspected fetal death. She underwent emergency cesarean section because fetal death had indeed occurred, and she was then admitted to the intensive care unit (ICU). Read More

    Management of severe dengue hemorrhagic fever and bleeding complications in a primigravida patient: a case report.
    J Med Case Rep 2016 Dec 20;10(1):357. Epub 2016 Dec 20.
    Department of Anesthesiology and Critical Care Medicine, 3rd floor, Siloam Hospitals Lippo Village, Jalan Siloam No. 6, Karawaci, 15811, Tangerang, Banten, Indonesia.
    Background: The incidence of dengue hemorrhagic fever is increasing among the adult population living in endemic areas. The disease carries a 0.73% fatality rate for the general population, but what happens when the disease strikes a special subpopulation group, the obstetrics? Perhaps the important question specific to this special subpopulation revolves around the right time and mode of delivery under severe coagulopathy and plasma leakage in conditions of imminent delivery. Read More

    Circulating heat shock protein mRNA profile in gestational hypertension, pre-eclampsia & foetal growth restriction.
    Indian J Med Res 2016 Aug;144(2):229-237
    The Third Faculty of Medicine, Institute for the Care of the Mother & Child, Charles University, Podolske Nabrezi 157/36, 147 00 Prague, Czech Republic.
    Background & Objectives: Heat shock proteins (Hsp) are ubiquitously distributed phylogenetically conserved molecules that regulate cellular homeostasis and maintain the integrity and function of cellular proteins. Increased levels of Hsp in maternal circulation have been shown to be associated with increased risk of pregnancy related complications. The objective of this study was to explore extracellular Hsp mRNA levels in maternal circulation and quantified Hsp27, Hsp60, Hsp70, Hsp90 and Hsp70 binding protein 1 (HspBP1) mRNAs in maternal plasma samples using real-time reverse-transcriptase polymerase chain reaction. Read More

    Hyperthyroidism secondary to hysterosalpingography: an extremely rare complication: A case report.
    Medicine (Baltimore) 2016 Dec;95(49):e5588
    aDepartment of Cardiac Surgery, Peking Union Medical College Hospital, Beijing, China bDepartment of Plastic Surgery, Plastic Surgery Hospital (Institute), Chinese Academy of Medical Science & Peking Union Medical College (CAMS & PUMC), Beijing, China.
    Rationale: Hysterosalpingography (HSG), a standard procedure for the evaluation of women with infertility and repetitive pregnancy loss, is associated with complications such as uterine perforation, infection, allergic reactions, syncope, hemorrhage and shock, and pulmonary or retinal embolus. However, hyperthyroidism has not been reported as one of its complications.

    Patient Concerns And Diagnoses: We report the case of a 33-year-old euthyroid woman who presented to our hospital with palpitation, hand tremor, fatigue, and excessive sweating after HSG. Read More

    Pancreatic and Hepatic Metastasis of an Undiagnosed Choriocarcinoma: An Exceptional Cause of Haemoperitoneum in Young Women - Report of a Rare Case.
    Case Rep Oncol 2016 Sep-Dec;9(3):633-638. Epub 2016 Oct 17.
    Department of Medicine, Ibri Regional Hospital, Ibri, Sultanate of Oman.
    Haemoperitoneum in women of reproductive age usually suggests either ruptured ectopic pregnancy or ruptured ovarian cysts. Metastatic choriocarcinoma is considered the least common cause of haemoperitoneum in women of childbearing age. We report a rare case of pancreatic and hepatic metastasis of choriocarcinoma in a young, 30-year-old female who had delivered 10 months prior at term gestation with no previous history of gestational trophoblastic disease or molar pregnancy. Read More

    What is the impact of extracorporeal shock wave lithotripsy on semen parameters? A systematic review and meta-analysis.
    Urologia 2017 Feb 2;84(1):28-34. Epub 2016 Dec 2.
    Urology and Nephrology Research Center, Shahid Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran - Iran.
    Background: Extracorporeal shock wave lithotripsy (ESWL) is an important tool for the management of urolithiasis. The effects of shockwaves on tissues are established. The aim of this meta-analysis is to evaluate the microscopic semen characteristics of young men before and after ESWL treatment for lower ureteral calculi. Read More

    Prenatal diagnosis of spontaneous twin anemia-polycythemia sequence and postnatal examination of placental vascular anastomoses.
    Obstet Gynecol Sci 2016 Nov 15;59(6):539-543. Epub 2016 Nov 15.
    Department of Obstetrics and Gynecology, Catholic University of Daegu School of Medicine, Daegu, Korea.
    Twin anemia-polycythemia sequence (TAPS) is characterized by a wide discrepancy of hemoglobin between two monochorionic fetuses without sign of twin oligo-polyhydramnios sequence. A primiparous woman with monochorionic diamniotic twin transferred for preterm labor. Ultrasonographic evaluation at 32+3 weeks of gestation revealed increased middle cerebral artery-peak systolic velocity (77. Read More

    Case Study: Obstetrical Trauma With Maternal Death and Fetal Survival.
    Crit Care Nurs Q 2017 Jan/Mar;40(1):36-40
    Shock Trauma Center, Allegheny General Hospital, Pittsburgh, Pennsylvania.
    Trauma during pregnancy is the leading cause of non-obstetric-related maternal and fetal death. This article summarizes obstetric physiology and outlines the assessment and treatment of traumatic injuries of the pregnant patient. A case is presented in which a pregnant woman with blunt abdominal trauma was managed efficiently in a trauma center within a hospital that does not have in-house obstetric services. Read More

    Cesarean section in the setting of severe pulmonary hypertension requiring extracorporeal life support.
    Gen Thorac Cardiovasc Surg 2016 Nov 25. Epub 2016 Nov 25.
    Division of Cardiac Surgery, The Johns Hopkins Hospital, Zayed 7107, 1800 Orleans St, Baltimore, MD, 21287, USA.
    We describe the use of veno-arterial extracorporeal membrane oxygenation (ECMO) in a 35-year-old female with severe fixed pulmonary hypertension who went into cardiogenic shock during a Cesarean section. Pregnancy in the presence of severe pulmonary hypertension is typically contraindicated due to high maternal mortality rates. This patient visited our hospital at 37 weeks of gestation after experiencing dyspnea and chest pain. Read More

    [Septic shock in pregnancy on the basis of an acute pyelonephritis].
    Ceska Gynekol 2016 ;81(4):286-288
    Objective: According to the World Health Organisation, sepsis is one of the four main causes of pregnancy-related mortality worldwide, together with hemorrhage, hypertensive disease and abortion. The main goal of this paper is an analysis of one case of septic shock in pregnancy.

    Design: A case report. Read More

    Veno-venous ECMO as a safe bridge to recovery in a patient with severe peripartum cardiomyopathy - learning from errors.
    Perfusion 2016 Nov 23. Epub 2016 Nov 23.
    Department of Intensive Care and Emergency Medicine, HELIOS Frankenwaldklinik Kronach, 96317 Kronach, Germany
    Peripartum cardiomyopathy (PPCM) is a rare disorder of unknown etiology and pathogenesis. The most important tool for diagnostic confirmation is transthoracic echocardiography. The recommended management of PPCM in pregnancy is summarized by the European Society of Cardiology Heart Failure Guidelines. Read More

    Management of uterine rupture: a case report and review of the literature.
    BMC Res Notes 2016 Nov 21;9(1):492. Epub 2016 Nov 21.
    Department of Obstetrics and Gynecology, Douala General Hospital, Douala, Cameroon.
    Background: Maternal morbidity and mortality has been a major World Health Organization concern over the years, especially in sub-Saharan Africa. This paper reports uterine rupture with severe hypovolemic shock managed at the Douala General Hospital, Cameroon. Early clinical diagnosis is paramount to maternal survival. Read More

    The Case for Improved Interprofessional Care: Fatal Analgesic Overdose Secondary to Acute Dental Pain during Pregnancy.
    Case Rep Dent 2016 26;2016:7467262. Epub 2016 Oct 26.
    Department of Oral and Maxillofacial Surgery/Hospital Dentistry, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
    Prenatal oral health extends beyond the oral cavity, impacting the general well-being of the pregnant patient and her fetus. This case report follows a 19-year-old pregnant female presenting with acute liver failure secondary to acetaminophen overdose for management of dental pain following extensive dental procedures. Through the course of her illness, the patient suffered adverse outcomes including fetal demise, acute kidney injury, spontaneous bacterial peritonitis, and septic shock before eventual death from multiple organ failure. Read More

    Cardiogenic shock in pregnancy: Analysis from the National Inpatient Sample.
    Hypertens Pregnancy 2016 Nov 11:1-7. Epub 2016 Nov 11.
    a Department of Anesthesia and Critical Care , University of Chicago , Chicago , Illinois , USA.
    Objective: Cardiogenic shock (CS) may occur during pregnancy and dramatically worsen peripartum outcomes.

    Methods: We analyzed the National Inpatient Sample from 2002 to 2013 to describe the incidence of, risk factors for and outcomes of CS during pregnancy.

    Results: Of the 53,794,192 hospitalizations analyzed, 2044 were complicated by CS. Read More

    The sheep conceptus modulates proteome profiles in caruncular endometrium during early pregnancy.
    Anim Reprod Sci 2016 Dec 2;175:48-56. Epub 2016 Nov 2.
    UMR BDR, INRA, ENVA, Université Paris Saclay, 78350 Jouy en Josas, France. Electronic address:
    The stage-specific expression of functional proteins within the endometrium, and their regulation by conceptus-derived signals, are crucial for conceptus development and successful establishment of pregnancy. Accurate knowledge of endometrium-conceptus interactions is key for the development of effective strategies to improve conceptus implantation rates both following natural conception and/or assisted reproductive technologies. The unilateral pregnant ewe provides a powerful experimental model for the study of endometrial function in the presence or absence of conceptuses during the peri-implantation period. Read More

    [Effectiveness of a Rapid Response Team (RRT) in a case of ruptured ectopic pregnancy].
    Rev Med Inst Mex Seguro Soc 2016 Nov-Dec;54(6):787-792
    Hospital General Regional 1 "Vicente Guerrero", Instituto Mexicano del Seguro Social, Acapulco, Guerrero, México.
    Background: An ectopic pregnancy happens when a fertilized egg attaches somewhere outside the endometrial surface. This sort of pregnancy has an estimated incidence of 1.6 to 2 each 100 births. Read More

    Management of Sepsis and Septic Shock for the Obstetrician-Gynecologist.
    Obstet Gynecol Clin North Am 2016 Dec;43(4):659-678
    Division of Maternal-Fetal Medicine, Department of Obstetrics & Gynecology, Drexel University College of Medicine, 245 North 15th Street, MS 495, Philadelphia, PA 19102, USA. Electronic address:
    The incidence of sepsis is increasing in the United States, both in the general adult population and among pregnant and postpartum women. Neither infection nor bacteremia are synonymous with sepsis: it is a dysregulated host response to a pathogen in which organ dysfunction is key. New clinical criteria have been released. Read More

    Clinical and microbiological features of maternal sepsis: a retrospective study.
    Int J Obstet Anesth 2017 Feb 10;29:26-33. Epub 2016 Sep 10.
    Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA.
    Background: Identifying pregnant women with sepsis is challenging because diagnostic clinical and laboratory criteria overlap with normal pregnant physiologic indices. Our primary study aim was to describe clinical and laboratory characteristics of women diagnosed with sepsis, severe sepsis and septic shock. Our secondary aim was to determine positive predictive values for International Classification of Disease (ICD)-9 billing codes for sepsis, severe sepsis, and septic shock. Read More

    Atraumatic diplaced bilateral femoral neck fracture in a patient with hypophosphatemic rickets in postpartum period: A missed diagnosis.
    Int J Surg Case Rep 2016 17;28:321-324. Epub 2016 Oct 17.
    Department of Orthopaedics and Traumatology, Faculty of Medicine, Erciyes University, Kayseri, Turkey.
    Introduction: Simultaneous bilateral femoral neck fracture is an uncommon condition. There are very few cases reported in the literature and most of these cases have underlying bone pathologies such as renal osteodystrophy and osteomalacia. In some cases bilateral femoral neck fractures occur due to generalized seizures or high-energy trauma. Read More

    Parents' perceptions of counselling following prenatal diagnosis of congenital anomalies of the kidney and urinary tract: a qualitative study.
    BJU Int 2017 Mar 23;119(3):474-481. Epub 2016 Oct 23.
    Discipline of Paediatrics, School of Women's and Children's Health, UNSW Medicine, The University of New South Wales, Sydney, NSW, Australia.
    Objectives: To explore parents' experiences of counselling after prenatal diagnosis of congenital anomalies of the kidney and urinary tract.

    Subjects And Methods: Parents of a child born between September 2012 and March 2015 with posterior urethral valves (PUV) or multicystic dysplastic kidney (MCDK) completed a semi-structured telephone interview, demographic survey, and the 21-item self-report Depression, Anxiety and Stress Scales questionnaire. Qualitative data were analysed thematically using NVivo10 software. Read More

    TNFα Variation During the Menstrual Cycle and Thereafter: A New Explanation for Gender-Based Disparities in ICU Admission Rates, Trauma Outcomes and General Mortality.
    Shock 2016 Oct 12. Epub 2016 Oct 12.
    *Department Urology, Péterfy Hospital, Budapest, Hungary †Military Hospital, Budapest, Hungary ‡Department Aerospace Medicine, University of Szeged, Hungary §Central Laboratory (Pest), Semmelweis University, Budapest, Hungary ¶Department Public Health, University of Pécs, Hungary ||Institute of Food, Brain and Behaviour, Oxford, England.
    Background: Multiple studies have found gender-based disparities in ICU admission rates and in complications following trauma. Female gender was associated with lower mortality when comparing patients less than 50 years of age. These data suggest an important role for cycle rather than gender itself. Read More

    Death of One Twin during the Perinatal Period: An Interpretative Phenomenological Analysis.
    J Palliat Med 2016 Oct 11. Epub 2016 Oct 11.
    2 Pregnancy Loss Research Group, University College Cork , Cork, Ireland .
    Background: Perinatal death is one of the most difficult bereavements due to the shock and profound grief experienced by parents. It has been established that such bereavement has a life-lasting impact. Twin pregnancy is associated with increased perinatal risk, with higher rates of perinatal mortality than in singleton pregnancy. Read More

    Heat shock protein-27 (HSP27) regulates STAT3 and eIF4G levels in first trimester human placenta.
    J Mol Histol 2016 Dec 6;47(6):555-563. Epub 2016 Oct 6.
    Oncogenetic Laboratory, Meir Medical Centre, 59 Tschernchovski St., 44281, Kfar Saba, Israel.
    During placental implantation, cytotrophoblast cells differentiate to extravillous trophoblast (EVT) cells that invade from the placenta into the maternal uterine blood vessels. The heat shock protein-27 (HSP27), the signal transducer and activator of transcription-3 (STAT3) and the eukaryotic translation initiation factor 4E (EIF4E) are involved in regulating EVT cell differentiation/migration. EIF4E and EIF4G compose the translation initiation complex, which is a major control point in protein translation. Read More

    Antenatal consultation following limb malformation discovery using ultrasound scan.
    Ann Phys Rehabil Med 2016 Sep;59S:e11
    Hôpitaux de Saint-Maurice, MPR, Saint-Maurice, France.
    Opinion/feedback: Our unit has been providing antenatal consultations for 30 years following the discovery of limb malformation with the fetus. Each of these consultations is specific and carried out by a multi-professional team. It requires a physical and rehabilitation doctor, an orthopedic surgeon, an occupational therapist for upper limb malformation, a physiotherapist for lower malformation and a psychologist. Read More

    Study of Obstetric Admissions to the Intensive Care Unit of a Tertiary Care Hospital.
    J Obstet Gynaecol India 2016 Oct 26;66(Suppl 1):12-7. Epub 2015 Aug 26.
    Department of Obstetrics and Gynecology, Bangalore Medical College and Research Institute, No. 620, A4 Block, Krishna Block, National Games Village, Koramangala, Bangalore, Karnataka 560047 India.
    Purpose: To analyze obstetric admissions to intensive care unit and to identify the risk factors responsible for intensive care admission.

    Methods: This is a retrospective study of all obstetric cases admitted to the intensive care unit over a period of 3 years. Data were collected from case records. Read More

    Salvage myocardial revascularisation in spontaneous left main coronary artery dissection with cardiogenic shock - the role of mechanical circulatory support.
    Perfusion 2017 Mar 24;32(2):171-173. Epub 2016 Sep 24.
    Department of Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton & Harefield NHS Foundation Trust, UK.
    Spontaneous left main coronary artery dissection is a rare cause of acute coronary events or sudden cardiac death, constituting less than 1% of all epicardial coronary artery dissections. It is often fatal and is mostly recognized at post-mortem examination in young victims of sudden death. More than 70% of the reported cases occurred in women, particularly during pregnancy and the peripartum period and those on oral contraceptives. Read More

    Neutrophil Extracellular Traps Promote Hypercoagulability in Patients With Sepsis.
    Shock 2017 Feb;47(2):132-139
    Department of Vascular Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
    Background: Patients with sepsis commonly exhibit a hypercoagulability with high risk of venous thromboembolism (VTE). Neutrophil extracellular traps (NETs) are found to trigger inflammation and coagulation. We aim to determine whether NETs promoted the hypercoagulability and early anticoagulation reduced NETs releasing during sepsis. Read More

    Adnexal germ cell carcinoma with bone metastases in pregnant women: case report and review.
    Medwave 2016 Aug 24;16(7):e6524. Epub 2016 Aug 24.
    Instituto de Evaluación de Tecnologías en Salud e Investigación, Seguro Social de Salud, Lima, Perú
    Germ cell carcinoma during pregnancy is rare. However, its detection has increased due to the use of ultrasound fetal monitoring in the antenatal care program. In this article, we present the case of a Germ cell carcinoma during pregnancy is rare. Read More

    Identification of coagulase-negative Staphylococcus saprophyticus by polymerase chain reaction based on the heat-shock repressor encoding hrcA gene.
    Diagn Microbiol Infect Dis 2016 Nov 11;86(3):253-256. Epub 2016 Aug 11.
    Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, Centro de Ciências da Saúde (CCS), Av. Carlos Chagas Filho, 373, Bloco I, Cidade Universitária, 21941-920Rio de Janeiro, RJ, Brazil. Electronic address:
    Staphylococcus saprophyticus is an uropathogen belonging to the human microbiota and is responsible for community-acquired infections of the urinary tract. Identification of Staphylococcus species by biochemical tests is laborious and costly when compared to routine laboratory tests. Because of their high sensitivity and specificity, molecular methods are better suited for accurate identification of Staphylococcusspp. Read More

    Low Neonatal Mortality and High Incidence of Infectious Diseases in a Vietnamese Province Hospital.
    Biomed Res Int 2016 11;2016:2087042. Epub 2016 Aug 11.
    Paediatric and Adolescence Clinic, Juliane Marie Centre, Rigshospitalet, Copenhagen, Denmark.
    Background. Neonatal deaths constitute the majority of child mortality in Vietnam, but studies are scarce and focus on community settings. Methods. Read More

    Radiological diagnosis of gas gangrene in a fetus at term.
    Taiwan J Obstet Gynecol 2016 Aug;55(4):582-4
    Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
    Objective: To report a case of gas gangrene in a fetus at term, which was diagnosed by antenatal computed tomography (CT) imaging.

    Case Report: A 23-year-old primiparous woman, who did not undergo any prenatal health checks until term, developed hypertension, proteinuria, and clouding of consciousness, and experienced intrauterine fetal death. A single, mature fetus with voluminous gas bubbles was observed on CT, which was consistent with a diagnosis of fetal gas gangrene. Read More

    Trophoblastic debris extruded from hydatidiform molar placentae activates endothelial cells: Possible relevance to the pathogenesis of preeclampsia.
    Placenta 2016 Sep 27;45:42-9. Epub 2016 Jul 27.
    Department of Obstetrics & Gynaecology, The University of Auckland, New Zealand; The Hospital of Obstetrics & Gynaecology, Fudan University, China. Electronic address:
    Introduction: Preeclampsia is currently thought to be induced by a placental factor that triggers maternal endothelial activation. It is now well known that trophoblastic debris shed from the placenta into the maternal blood is associated with this disease. Hydatidiform mole is a pathological pregnancy characterised by hyperplastic trophoblast with little or no fetal development. Read More

    Management of Maternal Cardiac Arrest in the Third Trimester of Pregnancy: A Simulation-Based Pilot Study.
    Crit Care Res Pract 2016 31;2016:5283765. Epub 2016 Jul 31.
    Summa Health System, Department of Medical Education, Virtual Care Medical Simulation Laboratory, Akron, OH 44304, USA.
    Objective. To evaluate confidence, knowledge, and competence after a simulation-based curriculum on maternal cardiac arrest in an Obstetrics & Gynecologic (OBGYN) residency program. Methods. Read More

    Maternal morbidity and mortality from severe sepsis: a national cohort study.
    BMJ Open 2016 Aug 23;6(8):e012323. Epub 2016 Aug 23.
    National Perinatal Epidemiology Unit (NPEU), Nuffield Department of Population Health, University of Oxford, Oxford, UK.
    Objectives: To describe the incidence, characteristics and risk factors for critical care admission with severe maternal sepsis in the UK.

    Design: National cohort study.

    Setting: 198 critical care units in the UK. Read More

    Experiences of termination of pregnancy for a fetal anomaly: A qualitative study of virtual community messages.
    Midwifery 2016 Oct 2;41:54-60. Epub 2016 Aug 2.
    Department of Public Health and Caring Sciences, Uppsala University, SE-75122, Uppsala, Sweden; Department of Health Care Sciences, Ersta Sköndal University College, SE-10061, Stockholm, Sweden.
    Objective: to explore experiences described by posters in Swedish virtual communities before, during and after termination of pregnancy due to a fetal anomaly.

    Design: cross-sectional qualitative study of messages in virtual communities. The messages were purposefully selected in 2014 and analyzed with inductive qualitative manifest content analysis. Read More

    Severe neonatal subgaleal hemorrhage as the first presentation of hemophilia A.
    Srp Arh Celok Lek 2016 Mar-Apr;144(3-4):204-6
    Introduction: Subgaleal hemorrhage is a rare but potentially fatal birth trauma. It is caused by rupture of the emissary veins (connections between the dural sinuses and scalp veins), followed by the accumulation of blood between the epicranial aponeurosis and the periosteum. Usually, it is associated with instrumental delivery (vacuum extraction, forceps delivery), but it may also occur spontaneously, suggesting the possibility of congenital bleeding disorder. Read More

    Successful delivery after surgical repair of uterine rupture at 15 weeks of gestation: case report and brief review.
    Eur J Obstet Gynecol Reprod Biol 2016 Sep 14;204:5-8. Epub 2016 Jun 14.
    Department of Obstetrics and Gynaecology, University of Eastern Piedmont, Novara, Italy.
    Objective: Second-trimester uterine rupture is a rare disorder and it is unclear if it should be managed with caesarean section, repair or hysterectomy. This article provides a case report of second-trimester uterine rupture repair, and reviews the risk factors, signs and symptoms, suturing technique and newborn outcome.

    Methods: PubMed was searched using the terms 'uterine rupture', 'second trimester' and 'repair' Only cases of second-trimester uterine rupture repair that led to successful prolongation of pregnancy were included. Read More

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