3,605 results match your criteria Sexually transmitted infections[Journal]


Association between STI and child sexual exploitation in children under 16 years old attending sexual health clinics in England: findings from a case-control study.

Sex Transm Infect 2019 Apr 17. Epub 2019 Apr 17.

GUM, Royal Hallamshire Hospital, Sheffield, UK.

Objective: Child sexual exploitation (CSE) can be difficult to identify, as there may be few reliable indicators. Although they may be used in decision-making, there is no evidence that STIs are predictors of CSE. We investigated the relationship between STI presentation at sexual health clinics (SHCs) and CSE. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053842DOI Listing

Evidence for a new paradigm of gonorrhoea transmission: cross-sectional analysis of infections by anatomical site in both partners in 60 male couples.

Sex Transm Infect 2019 Apr 17. Epub 2019 Apr 17.

Melbourne Sexual Health Centre, Carlton, Victoria, Australia.

Objective: Gonorrhoea transmission between men is currently thought to occur primarily to and from the urethra. Transmission without urethral involvement, from throat-to-throat and throat-to-anus, is considered to be uncommon. Using gonorrhoea results from male couples, we aimed to investigate the transmission dynamics of gonorrhoea. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053803DOI Listing
April 2019
3.401 Impact Factor

Clinical round-up.

Sex Transm Infect 2019 May;95(3):236

Sexual Health and HIV, Mortimer Market Centre, London, UK.

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2018-053779
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http://dx.doi.org/10.1136/sextrans-2018-053779DOI Listing
May 2019
1 Read

STI Foundation (STIF): latest developments and the future.

Sex Transm Infect 2019 May;95(3):162

Department of HIV and Sexual Health, Imperial College Healthcare NHS Trust, London, UK.

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2018-053820
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http://dx.doi.org/10.1136/sextrans-2018-053820DOI Listing
May 2019
1 Read

Supplemental testing is required to maintain control following a transition from Pap smear to HPV DNA testing for cervical screening: a mathematical modelling study.

Sex Transm Infect 2019 Apr 16. Epub 2019 Apr 16.

Kirby Institute, UNSW Sydney, Sydney, New South Wales, Australia.

Objectives: Using mathematical modelling, we have previously shown that the prevalence of infection with (TV) is likely to increase in the general population in Australia with the transition from Pap smear-based cervical screening to human papillomavirus (HPV) DNA testing. Here we use the existing model to estimate the level of supplemental testing required to maintain TV control.

Methods: A compartmental mathematical model describing the transmission of TV in the general heterosexual population in Australia was used to evaluate the impact of a range of screening scenarios on TV prevalence over time following the transition to HPV DNA testing for cervical screening. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053845DOI Listing

High burden of chlamydia and gonorrhoea in pharyngeal, rectal and urethral sites among Thai transgender women: implications for anatomical site selection for the screening of STI.

Sex Transm Infect 2019 Apr 13. Epub 2019 Apr 13.

PREVENTION, Thai Red Cross AIDS Research Centre, Bangkok, Thailand.

Objective: Comprehensive data on (CT) and (NG) infections to guide screening services among transgender women (TGW) are limited. We studied the burden of CT/NG infections in pharyngeal, rectal and urethral sites of Thai TGW and determined missed CT/NG diagnoses if selected site screening was performed.

Methods: Thai TGW were enrolled to the community-led test and treat cohort. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053835DOI Listing
April 2019
1 Read

Impact of mass drug administration of azithromycin for trachoma elimination on prevalence and azithromycin resistance of genital infection.

Sex Transm Infect 2019 Apr 13. Epub 2019 Apr 13.

Applied Diagnostic Research and Evaluation Unit, St George's, University of London, London, UK

Background: Mass drug administration (MDA) of 20 mg/kg (maximum 1 g in adults) azithromycin for ocular (CT) infection is a key component of the WHO trachoma elimination strategy. However, this dose may be suboptimal in infection and may encourage emergence of antimicrobial resistance (AMR) to azithromycin.

Objectives: To determine the effect of MDA for trachoma elimination on prevalence, strain type and azithromycin resistance. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053938DOI Listing

Borderline personality disorder is associated with an increased risk of sexually transmitted infections: A nationwide population-based cohort study in Taiwan.

Sex Transm Infect 2019 Apr 13. Epub 2019 Apr 13.

Department of Psychiatry, Tzu Chi General Hospital, and School of Medicine, Tzu Chi University, Hualien, Taiwan

Background: Several features of borderline personality disorder (BPD) are likely to be associated with sexual health problems, such as unstable attachment, unstable sexual identity and sexual impulsivity. Since the issue of sex is not openly discussed in Taiwanese society, sexual health needs, including screening and prevention of sexually transmitted infections (STI), are often neglected in this population.

Objective: The study aims to determine whether BPD is associated with an increased risk of subsequent STI in Taiwan. Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2018-053812
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http://dx.doi.org/10.1136/sextrans-2018-053812DOI Listing
April 2019
8 Reads

Psychosocial and sexual characteristics associated with sexualised drug use and chemsex among men who have sex with men (MSM) in the UK.

Sex Transm Infect 2019 Apr 12. Epub 2019 Apr 12.

Public Health Institute, Liverpool John Moores University, Liverpool, UK.

Objective: To understand how the emerging public health issue of chemsex relates to broader patterns of sexualised drug use (SDU) among men who have sex with men (MSM), which has been understudied.

Methods: Potential participants were invited to take part in an anonymous, cross-sectional online survey through Facebook advertising and community organisations' social media posts (April-June 2018). Multivariable logistic regression was used to compare MSM who engaged in recent SDU (past 12 months) with those who did not, and those who engaged in chemsex (γ-hydroxybutyrate/γ-butyrolactone, crystal methamphetamine, mephedrone, ketamine) with those who engaged in other SDU (eg, poppers, cocaine, cannabis). Read More

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http://dx.doi.org/10.1136/sextrans-2018-053933DOI Listing

Gonorrhoea and chlamydia in persons with HIV: number needed to screen.

Sex Transm Infect 2019 Apr 6. Epub 2019 Apr 6.

Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.

Objectives: Current guidelines recommend screening sexually active persons with HIV (PWH) for (NG) and (CT) at least annually. Yet, screening rates in many HIV clinics remain low. In this study, we estimated the number needed to screen (NNS) to detect a NG and/or CT infection at each anatomic site among different subpopulations of PWH. Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2018-053793
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http://dx.doi.org/10.1136/sextrans-2018-053793DOI Listing
April 2019
2 Reads

Exosomal microRNA profiles from serum and cerebrospinal fluid in neurosyphilis.

Sex Transm Infect 2019 Mar 29. Epub 2019 Mar 29.

Department of Dermatology, Zhejiang University School of Medicine, Second Affiliated Hospital, Hangzhou, China

Objective: Changes in microRNAs (miRNAs) in the cerebrospinal fluid (CSF) are associated with different neurological diseases. Since alternations of miRNAs in neurosyphilis are insufficiently investigated, we analysed miRNAs in the CSF of patients suffering from neurosyphilis.

Methods: Exosomes were isolated from serum and CSF. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053813DOI Listing
March 2019
2 Reads

Syphilitic hepatitis and neurosyphilis: an observational study of Danish HIV-infected individuals during a 13-year period.

Sex Transm Infect 2019 Mar 28. Epub 2019 Mar 28.

Department of Infectious Diseases, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

Objective: Syphilis is an STI that potentially affects any organ. Syphilitic hepatitis and neurosyphilis have been reported in both HIV-uninfected and HIV-infected individuals. The aim of this study was to investigate syphilitic hepatitis and neurosyphilis among HIV-infected individuals during a 13-year period. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053921DOI Listing

Predictive factors for HIV infection among men who have sex with men and who are seeking PrEP: a secondary analysis of the PROUD trial.

Sex Transm Infect 2019 Mar 27. Epub 2019 Mar 27.

Medical Research Council Clinical Trials Unit at University College London, London, UK.

Objectives: Pre-exposure prophylaxis (PrEP) is a highly effective method of HIV prevention for men who have sex with men (MSM). However, uncertainty remains around the optimal eligibility criteria for PrEP, specifically whether there are subgroups at low risk of HIV for whom PrEP might not be warranted.

Methods: PROUD was an open-label waitlist trial design that randomised MSM attending participating sexual health centres in England to receive PrEP immediately (IMM) or after a deferral period of 1 year (DEF). Read More

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http://dx.doi.org/10.1136/sextrans-2018-053808DOI Listing
March 2019
1 Read

Use of gay app and the associated HIV/syphilis risk among non-commercial men who have sex with men in Shenzhen, China: a serial cross-sectional study.

Sex Transm Infect 2019 Mar 27. Epub 2019 Mar 27.

Department of HIV/AIDS Control and Prevention, Shenzhen Center for Disease Control and Prevention, Shenzhen, China

Objectives: Geosocial networking application specific to men who have sex with men (MSM) (gay app) has revolutionised the social networking of MSM globally, much concern was raised over its linkage to HIV/syphilis risk. This study sought to examine the association between use of gay app and sexual behaviours and HIV/syphilis risk among Chinese MSM.

Methods: Eligible MSM were recruited through combined offline methods from 2015 to 2017 in Shenzhen, China, with data collected including demographics, sexual behaviours, app use, recreational drug use and HIV testing. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053902DOI Listing
March 2019
1 Read
3.401 Impact Factor

Extent and selectivity of sexual orientation disclosure and its association with HIV and other STI testing patterns among gay, bisexual and other men who have sex with men.

Sex Transm Infect 2019 Mar 27. Epub 2019 Mar 27.

Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.

Objectives: Gay, bisexual and other men who have sex with men (GBMSM) in Singapore may fear disclosing their sexual orientation to others due to negative societal attitudes, and the law that criminalises sexual relations between men, which may, in turn, impede access to HIV/sexually transmitted infection (STI)-related health services. This study attempts to determine how selective disclosure to varying social groups, and the extent of disclosure, may serve to impact HIV/STI testing patterns among GBMSM.

Methods: In this observational study, we recruited GBMSM in Singapore through an online cross-sectional survey disseminated via the smartphone app Grindr from 14 January to 11 February 2018. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053866DOI Listing
March 2019
1 Read

Incubation period and risk factors support sexual transmission of bacterial vaginosis in women who have sex with women.

Sex Transm Infect 2019 Mar 14. Epub 2019 Mar 14.

Biostatistics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.

Objective: The epidemiology of bacterial vaginosis (BV) favours sexual transmission of BV-associated bacteria. We examined incubation period and risk factors for incident BV (iBV) in a prospective study of women who have sex with women (WSW).

Methods: Using daily self-collected vaginal swabs, WSW with normal vaginal microbiota (no Amsel criteria and a Nugent score of 0-3) were followed for 90 days or until iBV (Nugent score 7-10 on at least 2-3 consecutive days). Read More

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http://dx.doi.org/10.1136/sextrans-2018-053824DOI Listing

Sex club/party attendance and STI among men who have sex with men: results from an online survey in New York City.

Sex Transm Infect 2019 Mar 13. Epub 2019 Mar 13.

Sociomedical Sciences, Columbia University Mailman School of Public Health, New York City, New York, USA.

Objective: Prior studies have shown that men who have sex with men (MSM) who attend sex clubs or parties are at higher risk for HIV and other STIs than those who do not. We sought to provide data about MSM who attend sex clubs/parties in New York City (NYC) in the era of biomedical HIV prevention. METHODS : We conducted an online survey among MSM in NYC (n=766) in 2016-2017 and investigated differences between those who reported never attending a sex club/party (non-attendees 50. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053816DOI Listing

Spontaneous clearance of urogenital, anorectal and oropharyngeal and in women, MSM and heterosexual men visiting the STI clinic: a prospective cohort study.

Sex Transm Infect 2019 Mar 11. Epub 2019 Mar 11.

Department of Sexual Health, Infectious Diseases and Environmental Health, Public Health Service South Limburg, Heerlen, The Netherlands.

Objective: (CT) and (NG) infections can clear without treatment. Despite high prevalence of anorectal infections in men who have sex with men (MSM) and women, studies on anorectal clearance are scarce. Moreover it is unknown whether bacterial load affects urogenital/anorectal CT clearance. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053825DOI Listing

HIV testing behaviour and HIV prevalence among female sex workers in Ukraine: findings from an Integrated Bio-Behavioural Survey, 2013-2014.

Sex Transm Infect 2019 May 6;95(3):193-200. Epub 2019 Mar 6.

Department of Community Health Sciences, Centre for Global Public Health, University of Manitoba, Winnipeg, Manitoba, Canada.

Objectives: Ukraine has one of the largest HIV epidemics in Europe, with high prevalence among female sex workers (FSWs). We aimed to identify factors associated with HIV testing and receipt of the test result in the last 12 months, HIV prevalence and self-reported positive status among FSWs in Ukraine.

Methods: We used data from an Integrated Bio-Behavioural Survey among FSWs conducted in 2013-2014. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053684DOI Listing
May 2019
3.401 Impact Factor

Syphilis associated with recreational drug use, depression and high-risk sexual behaviour in men who have sex with men: a case-control study in China.

Sex Transm Infect 2019 Mar 6. Epub 2019 Mar 6.

Child and Adolescent Health and Maternal Health, School of Public Health, Capital Medical University, Beijing, China, Beijing, China

Objective: We investigated syphilis prevalence among men who have sex with men (MSM) in China, as well as potential risk factors. Our principal hypothesis was that syphilis would be associated with the use of recreational drugs such as methamphetamines.

Methods: From April to October 2013, we used several methods to recruit MSM in Qingdao, collecting demographic/behavioural information via self-administrated questionnaires. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053878DOI Listing
March 2019
1 Read
3.401 Impact Factor

Choose to test: self-selected testing for sexually transmitted infections within an online service.

Sex Transm Infect 2019 May 5;95(3):171-174. Epub 2019 Mar 5.

School of Population Health and Environmental Sciences, King's College London, London, UK

Objective: To describe the outcomes of user-led, choice of test within an online sexual health service.

Methods: We analysed routinely collected data from a free, online sexual health service in Essex, UK that enabled users to select their tests. The service website provided information on all sexually transmitted infections, recommended a testing package based on sexuality and ethnicity, and invited users to modify this if they chose. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053796DOI Listing
May 2019
4 Reads

What are the motivations and barriers to pre-exposure prophylaxis (PrEP) use among black men who have sex with men aged 18-45 in London? Results from a qualitative study.

Sex Transm Infect 2019 Mar 4. Epub 2019 Mar 4.

Australian Research Centre for Sex, Health and Society, La Trobe University, Melbourne, Victoria, Australia.

Background: Black men who have sex with men (BMSM) have higher HIV incidence and prevalence when compared with other men who have sex with men, despite similar risk profiles. New prevention technologies, including pre-exposure prophylaxis (PrEP), may be effective in responding to these inequalities, provided they are appropriately targeted and acceptable to their intended beneficiaries. This study aims to understand the motivations and barriers of BMSM aged 18-45 to PrEP uptake. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053773DOI Listing

Rapid onset and progression of myelopathy following an STI: a case for screening?

Sex Transm Infect 2019 Mar 1. Epub 2019 Mar 1.

GU Medicine, Imperial College London, London, UK.

Human T lymphotropic virus type 1 (HTLV-1) is recognised as an STI with serious manifestations of the disease in approximately 10% of those infected. This case report is the first to describe the short interval from sexual acquisition of HTLV-1 to the onset of HTLV-1-associated myelopathy and rapid progression to spastic paraparesis. The number of adult infections in the UK per annum is unknown, but surveillance data indicate that around 30% of newly diagnosed infections are occurring in persons born in the UK, rather than in migrants from HTLV-1-endemic regions. Read More

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http://dx.doi.org/10.1136/sextrans-2019-053978DOI Listing

Associations of depression and anxiety symptoms with sexual behaviour in women and heterosexual men attending sexual health clinics: a cross-sectional study.

Sex Transm Infect 2019 Feb 27. Epub 2019 Feb 27.

Institute for Global Health, University College London, Royal Free Hospital, London, UK.

Objective: To assess the association of symptoms of depression and anxiety with sexual risk behaviour and history, among women and heterosexual men attending genitourinary medicine (GUM) clinics.

Methods: Attitudes to and Understanding of Risk of Acquisition of HIV (AURAH) was a cross-sectional, self-administered questionnaire study recruited from 20 GUM clinics in England, 2013-2014. This analysis included women and heterosexual men. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053689DOI Listing
February 2019

Weekend services in an integrated contraception and sexual health clinic.

Sex Transm Infect 2019 Mar;95(2):158

Genito Urinary Medicine, North West Anglia NHS Foundation Trust, Huntingdon, Cambridgeshire PE296NT, UK.

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http://dx.doi.org/10.1136/sextrans-2018-053851DOI Listing
March 2019
2 Reads

The ABC of Sexual Dysfunction conference.

Sex Transm Infect 2019 Mar;95(2):82

GU Medicine, St Mary's Hospital London, London, UK.

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http://dx.doi.org/10.1136/sextrans-2018-053703DOI Listing

Being part of the solution.

Sex Transm Infect 2019 Mar;95(2):81

Institute of Infection and Global Health, University of Liverpool, Liverpool L69 7BE, UK

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2019-053994
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http://dx.doi.org/10.1136/sextrans-2019-053994DOI Listing
March 2019
5 Reads

Is there life beyond

Authors:
Jackie A Cassell

Sex Transm Infect 2019 Mar;95(2):79-80

Department of Primary Care and Public Health, Brighton and Sussex Medical School, Brighton BN1 9PX, UK

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http://dx.doi.org/10.1136/sextrans-2019-053998DOI Listing

Age-disparate partnerships and HSV-2 among adolescent girls and young women in South Africa: implications for HIV infection risk.

Sex Transm Infect 2019 Feb 8. Epub 2019 Feb 8.

Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, South Africa.

Objective: There is an urgent need to understand high HIV-infection rates among young women in sub-Saharan Africa. While age-disparate partnerships have been characterised with high-risk sexual behaviours, the mechanisms through which these partnerships may increase HIV-risk are not fully understood. This study assessed the association between age-disparate partnerships and herpes simplex virus type-2 (HSV-2) infection, a factor known to increase HIV-infection risk. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053577DOI Listing
February 2019
1 Read

Standardisation is necessary in urogenital and extragenital bacterial load determination by quantitative PCR: a review of literature and retrospective study.

Sex Transm Infect 2019 Feb 7. Epub 2019 Feb 7.

Department of Medical Microbiology, Maastricht University Medical Center, School of Public Health and Primary Care, Maastricht, The Netherlands.

Objectives: Pathogen load has been linked to disease severity in patients infected with HIV, resulting in international standards to adequately and reproducibly quantify load. (CT) load has been inconsistently linked to disease severity since extensive differences exist in quantification methods (14 methods in 28 articles). Differences include normalisation for human cell load due to CT's intracellular nature, despite the inability to distinguish inflammatory cells from epithelial cells with molecular techniques. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053522DOI Listing
February 2019
1 Read

Increasing adolescent girls' ability to identify STI-risk characteristics of sexual partners: a pilot study within an alternative disciplinary school.

Sex Transm Infect 2019 Feb 7. Epub 2019 Feb 7.

Department of Health Outcomes and Biomedical Informatics, College of Medicine, University of Florida, Gainesville, Florida, USA

Objectives: We evaluated the feasibility of conducting a 9-week long sexually transmitted infection (STI) prevention intervention, within an alternative disciplinary school for adolescent girls.

Methods: All girls who were 16-18 years old, enrolled in the school and did not have plans to transfer from the school were eligible to participate. We measured process feasibility with recruitment, retention and participant enjoyment. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053674DOI Listing
February 2019

Declines in anogenital warts diagnoses since the change in 2012 to use the quadrivalent HPV vaccine in England: data to end 2017.

Sex Transm Infect 2019 Feb 5. Epub 2019 Feb 5.

Blood Safety, Hepatitis, Sexually Transmitted Infections (STI) and HIV Service, National Infection Service, Public Health England, London, UK.

Objectives: In 2008, a national human papillomavirus (HPV) vaccination programme for females was introduced in England using the bivalent vaccine (HPV16 and 18 only). In 2012, the programme changed to offer the quadrivalent vaccine that includes protection against the two HPV types that cause the majority of anogenital warts (AGW; HPV6 and 11). We present data reporting AGW diagnoses in sexual health clinics (SHCs) in England to the end of 2017, including diagnoses among birth cohorts offered the quadrivalent vaccine. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053751DOI Listing
February 2019

Epidemiology of genital warts in the British population: implications for HPV vaccination programmes.

Sex Transm Infect 2019 Feb 5. Epub 2019 Feb 5.

Mortimer Market Centre, Institute for Global Health, University College London, London, UK.

Objectives: To estimate the prevalence of, and describe risk factors for, genital warts (GWs) in the British population, following the introduction of the bivalent (human papillomavirus (HPV)-16/18) vaccination programme in girls, and prior to the switch to quadrivalent (HPV-6/11/16/18) vaccine (offering direct protection against GWs) and compare this with GW diagnoses in the prevaccination era.

Methods: Natsal-3, a probability sample survey in Britain, conducted in 2010-2012, interviewed 9902 men and women aged 16-44. Natsal-2, conducted in 1999-2001, surveyed 11 161 men and women aged 16-44. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053786DOI Listing
February 2019

Prevalence and risk factors of anogenital human papillomavirus infection in a community sample of men who have sex with men in Taiwan: baseline findings from a cohort study.

Sex Transm Infect 2019 Jan 29. Epub 2019 Jan 29.

Fengshan Lee Chia Wen Urologic Clinic, Kaohsiung, Taiwan.

Objectives: Men who have sex with men (MSM) are a highly neglected population in the current recommendation of girls-only human papillomavirus (HPV) vaccination programmes in many countries. To better assess the cost effectiveness of HPV vaccination among men requires data on the prevalence of HPV infection in MSM using a community sample, which is still sparse in several regions. We examined the prevalence of and factors associated with anogenital HPV infection among MSM in Taiwan. Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2018-053629
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http://dx.doi.org/10.1136/sextrans-2018-053629DOI Listing
January 2019
12 Reads

Association between vaginal washing and detection of by culture and quantitative PCR in HIV-seronegative Kenyan women: a cross-sectional analysis.

Sex Transm Infect 2019 Jan 29. Epub 2019 Jan 29.

Department of Epidemiology, University of Washington, Seattle, Washington, USA.

Objectives: Vaginal washing has been associated with reductions in cultivable and an increased risk of both bacterial vaginosis (BV) and HIV infection. The effect of vaginal washing on the quantity of individual species is not well characterised. This analysis tested the hypothesis that vaginal washing would be associated with a lower likelihood of spp. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053769DOI Listing
January 2019
3 Reads

The Denominator problem: estimating the size of local populations of men-who-have-sex-with-men and rates of HIV and other STIs in Switzerland.

Sex Transm Infect 2019 Jan 24. Epub 2019 Jan 24.

Communicable Diseases Division, Swiss Federal Office of Public Health, Bern, Switzerland.

Objectives: There is no estimate of the current number of men who have sex with men (MSM) in Switzerland, or of their geographical distribution. We aimed to (1) estimate MSM concentration factors and population sizes for 83 Swiss postal code areas (PCA), including the nine largest Swiss cities, and (2) calculate MSM-specific local HIV prevalence and yearly rates of diagnosed HIV, hepatitis C virus (HCV), syphilis and gonorrhoea.

Methods: We triangulated data from general population estimates, MSM online surveys, published data on HIV prevalence and Swiss notification data for HIV and STDs. Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2017-053363
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http://dx.doi.org/10.1136/sextrans-2017-053363DOI Listing
January 2019
10 Reads

Prevalence of human papillomavirus-related diseases in the Republic of Korea: a cross-sectional study.

Sex Transm Infect 2019 Jan 24. Epub 2019 Jan 24.

Department of Cancer Control and Population Health, National Cancer Center Graduate School of Cancer Science and Policy, Goyang, Republic of Korea

Objective: We aimed to evaluate trends in the prevalence of human papillomavirus (HPV)-related diseases in the era before the introduction of organised HPV vaccination programmes in the Republic of Korea.

Methods: This cross-sectional study used National Health Insurance Service data from 2002 to 2015 and included participants who were diagnosed with the following HPV-related diseases (codes from the International Classification of Diseases, 10th Revision): genital warts (A63.0); cancer in the head and neck (C00-C10), anus (C21), vulva (C51), vagina (C52), cervix uteri (C53) and penis (C60); carcinoma in situ (CIS) of the lip/oral cavity/pharynx (D00. Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2018-053742
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http://dx.doi.org/10.1136/sextrans-2018-053742DOI Listing
January 2019
12 Reads

Indicator condition-guided HIV testing with an electronic prompt in primary healthcare: a before and after evaluation of an intervention.

Sex Transm Infect 2019 Jan 24. Epub 2019 Jan 24.

Hospital Clínico y Provincial de Barcelona, Unidad de Enfermedades Infecciosas, Barcelona, Spain.

Objective: Indicator condition (IC)-guided HIV testing is a strategy for the diagnosis of patients with HIV. The aim of this study was to assess the impact on the proportion of HIV tests requested after the introduction of an electronic prompt instructing primary healthcare (PHC) physicians to request an HIV test when diagnosing predefined IC.

Methods: A prospective interventional study was conducted in 2015 in three PHC centres in Barcelona to assess the number of HIV test requests made during the implementation of an electronic prompt. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053792DOI Listing
January 2019
1 Read

Systematic review and evidence synthesis of non-cervical human papillomavirus-related disease health system costs and quality of life estimates.

Sex Transm Infect 2019 02 21;95(1):28-35. Epub 2018 Sep 21.

National Infection Service, Public Health England, London, UK

Background: Many economic evaluations of human papillomavirus vaccination should ideally consider multiple disease outcomes, including anogenital warts, respiratory papillomatosis and non-cervical cancers (eg, anal, oropharyngeal, penile, vulvar and vaginal cancers). However, published economic evaluations largely relied on estimates from single studies or informal rapid literature reviews.

Methods: We conducted a systematic review of articles up to June 2016 to identify costs and utility estimates admissible for an economic evaluation from a single-payer healthcare provider's perspective. Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2018-053606
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http://dx.doi.org/10.1136/sextrans-2018-053606DOI Listing
February 2019
7 Reads

UK diploma examinations in genitourinary and HIV medicine.

Sex Transm Infect 2019 02;95(1)

Croydon Health Services NHS Trust, Croydon, UK.

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http://dx.doi.org/10.1136/sextrans-2018-053761DOI Listing
February 2019
9 Reads

Evaluation and enumeration of online test providers for sexually transmitted infections, specifically chlamydia, in the Netherlands.

Sex Transm Infect 2019 Jan 22. Epub 2019 Jan 22.

Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.

Objectives: Online testing for STIs might complement regular care provided by general practitioners or STI clinics. Two types of online testing can be distinguished, self-testing and self-sampling (sending sample to a laboratory for diagnosis). Online testing can occur without consultation with a healthcare professional, therefore information given by providers is essential for informed decision-making. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053771DOI Listing
January 2019
6 Reads

Baseline HPV prevalence in rectal swabs from men attending a sexual health clinic in Scotland: assessing the potential impact of a selective HPV vaccination programme for men who have sex with men.

Sex Transm Infect 2019 Jan 13. Epub 2019 Jan 13.

Health Protection Scotland, Glasgow, UK.

Objectives: A human papillomavirus (HPV) vaccination programme targeted towards men who have sex with men who are disproportionately affected by HPV anogenital infection and related disease was established in Scotland in July 2017. We aimed to establish a baseline HPV prevalence to assess the potential impact of the programme.

Methods: Residual rectal swabs taken in a sexual health clinic (n=1 248) were tested for the presence of HPV and HPV-type prevalence was collated and stratified by age. Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2018-053668
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http://dx.doi.org/10.1136/sextrans-2018-053668DOI Listing
January 2019
20 Reads

Human papillomavirus DNA detected in fingertip, oral and bathroom samples from unvaccinated adolescent girls in Tanzania.

Sex Transm Infect 2019 Jan 13. Epub 2019 Jan 13.

Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, UK.

Objective: Human papillomavirus (HPV) DNA has been detected in vaginal samples from adolescent girls who report no previous sex and, in high-income settings, from fingertips, raising the possibility of non-sexual transmission. No such studies originate from East Africa which bears among the highest cervical cancer incidence and HPV prevalence worldwide. HPV-related oral cancer incidence is increasing, but oral HPV prevalence data from East Africa are limited. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053756DOI Listing
January 2019
3 Reads

Post-test comparison of HIV test knowledge and changes in sexual risk behaviour between clients accessing HIV testing online versus in-clinic.

Sex Transm Infect 2019 Mar 13;95(2):102-107. Epub 2019 Jan 13.

Clinical Prevention Services, British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada

Objective: Internet-based HIV testing offers the potential to address privacy-related barriers to testing and increase frequency of testing but may result in missed opportunities related to sexual health education and prevention that typically occur in face-to-face encounters. In this study, we assessed the HIV test knowledge and sexual risk behaviour of clients testing for HIV through , an internet-based sexually transmitted and bloodborne infection testing platform inclusive of HIV testing, in comparison to clients testing through a large sexual health clinic.

Methods: We concurrently recruited clients and clinic clients from Vancouver, Canada, over the course of a 10-month period during 2015-2016. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053652DOI Listing
March 2019
3.401 Impact Factor

Qualitative analysis of the experiences of gay, bisexual and other men who have sex with men who use : a comprehensive internet-based diagnostic service for HIV and other STIs.

Sex Transm Infect 2019 Mar 13;95(2):145-150. Epub 2019 Jan 13.

School of Population and Public Health, University of British Columbia, Vancouver, Canada.

Objectives: To describe the factors that influence gay, bisexual and other men who have sex with men's (gbMSM) experiences with (GCO) in British Columbia (BC), Canada. GCO clients complete an internet-based risk assessment and print a laboratory test requisition form for HIV and other STIs to take to a private laboratory for diagnostic services.

Methods: Drawing on a purposive stratified sampling framework, we conducted 37 in-depth semistructured interviews with gbMSM who had used GCO at least once between 2015 and 2017. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053645DOI Listing
March 2019
2 Reads

Use of, and likelihood of using, HIV pre-exposure prophylaxis among men who have sex with men in Europe and Central Asia: findings from a 2017 large geosocial networking application survey.

Sex Transm Infect 2019 May 5;95(3):187-192. Epub 2019 Jan 5.

European Centre for Disease Prevention and Control, Solna, Sweden.

Objective: Currently, seven European countries provide HIV pre-exposure prophylaxis (PrEP) through public health services, although there are numerous reports of off-licence use. The objective of this study was to examine current use of PrEP, likelihood of future use and indicators of potential PrEP candidacy among an opportunistic sample of men who have sex with men in Europe and Central Asia.

Methods: A survey was sent out in eight languages to users of the Hornet gay networking application in July and August 2017. Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2018-053705
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http://dx.doi.org/10.1136/sextrans-2018-053705DOI Listing
May 2019
20 Reads

Relation between infection and pelvic inflammatory disease, ectopic pregnancy and tubal factor infertility in a Dutch cohort of women previously tested for chlamydia in a chlamydia screening trial.

Sex Transm Infect 2019 Jan 3. Epub 2019 Jan 3.

Epidemiology and Surveillance Unit, Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.

Objectives: A better understanding of infection (chlamydia)-related sequelae can provide a framework for effective chlamydia control strategies. The objective of this study was to estimate risks and risk factors of pelvic inflammatory disease (PID), ectopic pregnancy and tubal factor infertility (TFI) with a follow-up time of up until 8 years in women previously tested for chlamydia in the Chlamydia Screening Implementation study (CSI) and participating in the Netherlands Chlamydia Cohort Study (NECCST).

Methods: Women who participated in the CSI 2008-2011 (n=13 498) were invited in 2015-2016 for NECCST. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053778DOI Listing
January 2019
10 Reads

Dual screen and confirm rapid test does not reduce overtreatment of syphilis in pregnant women living in a non-venereal treponematoses endemic region: a field evaluation among antenatal care attendees in Burkina Faso.

Sex Transm Infect 2018 Dec 22. Epub 2018 Dec 22.

Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.

Objectives: In resource-limited settings, screening pregnant women for syphilis using rapid diagnostic tests (RDTs) is a key tool in the prevention of congenital syphilis. However, most syphilis RDTs detect only treponemal antibodies (T-RDT), meaning antibiotics may be provided unnecessarily to previously treated pregnant women, particularly in non-venereal treponematoses endemic regions. We estimated the potential reduction in overtreatment when comparing T-RDT (SD Bioline) to a newer rapid test (Dual Path Platform (DPP) Screen and Confirm Assay, Chembio) detecting both treponemal and non-treponemal antibodies. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053722DOI Listing
December 2018