3,576 results match your criteria Sexually transmitted infections[Journal]


Age-disparate partnerships and HSV-2 among adolescent girls and young women in South Africa: implications for HIV infection risk.

Sex Transm Infect 2019 Feb 8. Epub 2019 Feb 8.

Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, South Africa.

Objective: There is an urgent need to understand high HIV-infection rates among young women in sub-Saharan Africa. While age-disparate partnerships have been characterised with high-risk sexual behaviours, the mechanisms through which these partnerships may increase HIV-risk are not fully understood. This study assessed the association between age-disparate partnerships and herpes simplex virus type-2 (HSV-2) infection, a factor known to increase HIV-infection risk. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053577DOI Listing
February 2019
1 Read

Standardisation is necessary in urogenital and extragenital bacterial load determination by quantitative PCR: a review of literature and retrospective study.

Sex Transm Infect 2019 Feb 7. Epub 2019 Feb 7.

Department of Medical Microbiology, Maastricht University Medical Center, School of Public Health and Primary Care, Maastricht, The Netherlands.

Objectives: Pathogen load has been linked to disease severity in patients infected with HIV, resulting in international standards to adequately and reproducibly quantify load. (CT) load has been inconsistently linked to disease severity since extensive differences exist in quantification methods (14 methods in 28 articles). Differences include normalisation for human cell load due to CT's intracellular nature, despite the inability to distinguish inflammatory cells from epithelial cells with molecular techniques. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053522DOI Listing
February 2019

Increasing adolescent girls' ability to identify STI-risk characteristics of sexual partners: a pilot study within an alternative disciplinary school.

Sex Transm Infect 2019 Feb 7. Epub 2019 Feb 7.

Department of Health Outcomes and Biomedical Informatics, College of Medicine, University of Florida, Gainesville, Florida, USA

Objectives: We evaluated the feasibility of conducting a 9-week long sexually transmitted infection (STI) prevention intervention, within an alternative disciplinary school for adolescent girls.

Methods: All girls who were 16-18 years old, enrolled in the school and did not have plans to transfer from the school were eligible to participate. We measured process feasibility with recruitment, retention and participant enjoyment. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053674DOI Listing
February 2019

Declines in anogenital warts diagnoses since the change in 2012 to use the quadrivalent HPV vaccine in England: data to end 2017.

Sex Transm Infect 2019 Feb 5. Epub 2019 Feb 5.

Blood Safety, Hepatitis, Sexually Transmitted Infections (STI) and HIV Service, National Infection Service, Public Health England, London, UK.

Objectives: In 2008, a national human papillomavirus (HPV) vaccination programme for females was introduced in England using the bivalent vaccine (HPV16 and 18 only). In 2012, the programme changed to offer the quadrivalent vaccine that includes protection against the two HPV types that cause the majority of anogenital warts (AGW; HPV6 and 11). We present data reporting AGW diagnoses in sexual health clinics (SHCs) in England to the end of 2017, including diagnoses among birth cohorts offered the quadrivalent vaccine. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053751DOI Listing
February 2019

Epidemiology of genital warts in the British population: implications for HPV vaccination programmes.

Sex Transm Infect 2019 Feb 5. Epub 2019 Feb 5.

Mortimer Market Centre, Institute for Global Health, University College London, London, UK.

Objectives: To estimate the prevalence of, and describe risk factors for, genital warts (GWs) in the British population, following the introduction of the bivalent (human papillomavirus (HPV)-16/18) vaccination programme in girls, and prior to the switch to quadrivalent (HPV-6/11/16/18) vaccine (offering direct protection against GWs) and compare this with GW diagnoses in the prevaccination era.

Methods: Natsal-3, a probability sample survey in Britain, conducted in 2010-2012, interviewed 9902 men and women aged 16-44. Natsal-2, conducted in 1999-2001, surveyed 11 161 men and women aged 16-44. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053786DOI Listing
February 2019

Prevalence and risk factors of anogenital human papillomavirus infection in a community sample of men who have sex with men in Taiwan: baseline findings from a cohort study.

Sex Transm Infect 2019 Jan 29. Epub 2019 Jan 29.

Fengshan Lee Chia Wen Urologic Clinic, Kaohsiung, Taiwan.

Objectives: Men who have sex with men (MSM) are a highly neglected population in the current recommendation of girls-only human papillomavirus (HPV) vaccination programmes in many countries. To better assess the cost effectiveness of HPV vaccination among men requires data on the prevalence of HPV infection in MSM using a community sample, which is still sparse in several regions. We examined the prevalence of and factors associated with anogenital HPV infection among MSM in Taiwan. Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2018-053629
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http://dx.doi.org/10.1136/sextrans-2018-053629DOI Listing
January 2019
4 Reads

Association between vaginal washing and detection of by culture and quantitative PCR in HIV-seronegative Kenyan women: a cross-sectional analysis.

Sex Transm Infect 2019 Jan 29. Epub 2019 Jan 29.

Department of Epidemiology, University of Washington, Seattle, Washington, USA.

Objectives: Vaginal washing has been associated with reductions in cultivable and an increased risk of both bacterial vaginosis (BV) and HIV infection. The effect of vaginal washing on the quantity of individual species is not well characterised. This analysis tested the hypothesis that vaginal washing would be associated with a lower likelihood of spp. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053769DOI Listing
January 2019
1 Read

The Denominator problem: estimating the size of local populations of men-who-have-sex-with-men and rates of HIV and other STIs in Switzerland.

Sex Transm Infect 2019 Jan 24. Epub 2019 Jan 24.

Communicable Diseases Division, Swiss Federal Office of Public Health, Bern, Switzerland.

Objectives: There is no estimate of the current number of men who have sex with men (MSM) in Switzerland, or of their geographical distribution. We aimed to (1) estimate MSM concentration factors and population sizes for 83 Swiss postal code areas (PCA), including the nine largest Swiss cities, and (2) calculate MSM-specific local HIV prevalence and yearly rates of diagnosed HIV, hepatitis C virus (HCV), syphilis and gonorrhoea.

Methods: We triangulated data from general population estimates, MSM online surveys, published data on HIV prevalence and Swiss notification data for HIV and STDs. Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2017-053363
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http://dx.doi.org/10.1136/sextrans-2017-053363DOI Listing
January 2019
3 Reads

Prevalence of human papillomavirus-related diseases in the Republic of Korea: a cross-sectional study.

Sex Transm Infect 2019 Jan 24. Epub 2019 Jan 24.

Department of Cancer Control and Population Health, National Cancer Center Graduate School of Cancer Science and Policy, Goyang, Republic of Korea

Objective: We aimed to evaluate trends in the prevalence of human papillomavirus (HPV)-related diseases in the era before the introduction of organised HPV vaccination programmes in the Republic of Korea.

Methods: This cross-sectional study used National Health Insurance Service data from 2002 to 2015 and included participants who were diagnosed with the following HPV-related diseases (codes from the International Classification of Diseases, 10th Revision): genital warts (A63.0); cancer in the head and neck (C00-C10), anus (C21), vulva (C51), vagina (C52), cervix uteri (C53) and penis (C60); carcinoma in situ (CIS) of the lip/oral cavity/pharynx (D00. Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2018-053742
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http://dx.doi.org/10.1136/sextrans-2018-053742DOI Listing
January 2019
2 Reads

Indicator condition-guided HIV testing with an electronic prompt in primary healthcare: a before and after evaluation of an intervention.

Sex Transm Infect 2019 Jan 24. Epub 2019 Jan 24.

Hospital Clínico y Provincial de Barcelona, Unidad de Enfermedades Infecciosas, Barcelona, Spain.

Objective: Indicator condition (IC)-guided HIV testing is a strategy for the diagnosis of patients with HIV. The aim of this study was to assess the impact on the proportion of HIV tests requested after the introduction of an electronic prompt instructing primary healthcare (PHC) physicians to request an HIV test when diagnosing predefined IC.

Methods: A prospective interventional study was conducted in 2015 in three PHC centres in Barcelona to assess the number of HIV test requests made during the implementation of an electronic prompt. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053792DOI Listing
January 2019

Systematic review and evidence synthesis of non-cervical human papillomavirus-related disease health system costs and quality of life estimates.

Sex Transm Infect 2019 Feb 21;95(1):28-35. Epub 2018 Sep 21.

National Infection Service, Public Health England, London, UK

Background: Many economic evaluations of human papillomavirus vaccination should ideally consider multiple disease outcomes, including anogenital warts, respiratory papillomatosis and non-cervical cancers (eg, anal, oropharyngeal, penile, vulvar and vaginal cancers). However, published economic evaluations largely relied on estimates from single studies or informal rapid literature reviews.

Methods: We conducted a systematic review of articles up to June 2016 to identify costs and utility estimates admissible for an economic evaluation from a single-payer healthcare provider's perspective. Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2018-053606
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http://dx.doi.org/10.1136/sextrans-2018-053606DOI Listing
February 2019
4 Reads

UK diploma examinations in genitourinary and HIV medicine.

Sex Transm Infect 2019 Feb;95(1)

Croydon Health Services NHS Trust, Croydon, UK.

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http://dx.doi.org/10.1136/sextrans-2018-053761DOI Listing
February 2019
1 Read

Evaluation and enumeration of online test providers for sexually transmitted infections, specifically chlamydia, in the Netherlands.

Sex Transm Infect 2019 Jan 22. Epub 2019 Jan 22.

Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.

Objectives: Online testing for STIs might complement regular care provided by general practitioners or STI clinics. Two types of online testing can be distinguished, self-testing and self-sampling (sending sample to a laboratory for diagnosis). Online testing can occur without consultation with a healthcare professional, therefore information given by providers is essential for informed decision-making. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053771DOI Listing
January 2019
1 Read

Baseline HPV prevalence in rectal swabs from men attending a sexual health clinic in Scotland: assessing the potential impact of a selective HPV vaccination programme for men who have sex with men.

Sex Transm Infect 2019 Jan 13. Epub 2019 Jan 13.

Health Protection Scotland, Glasgow, UK.

Objectives: A human papillomavirus (HPV) vaccination programme targeted towards men who have sex with men who are disproportionately affected by HPV anogenital infection and related disease was established in Scotland in July 2017. We aimed to establish a baseline HPV prevalence to assess the potential impact of the programme.

Methods: Residual rectal swabs taken in a sexual health clinic (n=1 248) were tested for the presence of HPV and HPV-type prevalence was collated and stratified by age. Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2018-053668
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http://dx.doi.org/10.1136/sextrans-2018-053668DOI Listing
January 2019
8 Reads

Human papillomavirus DNA detected in fingertip, oral and bathroom samples from unvaccinated adolescent girls in Tanzania.

Sex Transm Infect 2019 Jan 13. Epub 2019 Jan 13.

Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, UK.

Objective: Human papillomavirus (HPV) DNA has been detected in vaginal samples from adolescent girls who report no previous sex and, in high-income settings, from fingertips, raising the possibility of non-sexual transmission. No such studies originate from East Africa which bears among the highest cervical cancer incidence and HPV prevalence worldwide. HPV-related oral cancer incidence is increasing, but oral HPV prevalence data from East Africa are limited. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053756DOI Listing
January 2019
1 Read

Post-test comparison of HIV test knowledge and changes in sexual risk behaviour between clients accessing HIV testing online versus in-clinic.

Sex Transm Infect 2019 Jan 13. Epub 2019 Jan 13.

Clinical Prevention Services, British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada

Objective: Internet-based HIV testing offers the potential to address privacy-related barriers to testing and increase frequency of testing but may result in missed opportunities related to sexual health education and prevention that typically occur in face-to-face encounters. In this study, we assessed the HIV test knowledge and sexual risk behaviour of clients testing for HIV through , an internet-based sexually transmitted and bloodborne infection testing platform inclusive of HIV testing, in comparison to clients testing through a large sexual health clinic.

Methods: We concurrently recruited clients and clinic clients from Vancouver, Canada, over the course of a 10-month period during 2015-2016. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053652DOI Listing
January 2019
3.401 Impact Factor

Qualitative analysis of the experiences of gay, bisexual and other men who have sex with men who use : a comprehensive internet-based diagnostic service for HIV and other STIs.

Sex Transm Infect 2019 Jan 13. Epub 2019 Jan 13.

School of Population and Public Health, University of British Columbia, Vancouver, Canada.

Objectives: To describe the factors that influence gay, bisexual and other men who have sex with men's (gbMSM) experiences with (GCO) in British Columbia (BC), Canada. GCO clients complete an internet-based risk assessment and print a laboratory test requisition form for HIV and other STIs to take to a private laboratory for diagnostic services.

Methods: Drawing on a purposive stratified sampling framework, we conducted 37 in-depth semistructured interviews with gbMSM who had used GCO at least once between 2015 and 2017. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053645DOI Listing
January 2019
1 Read

Use of, and likelihood of using, HIV pre-exposure prophylaxis among men who have sex with men in Europe and Central Asia: findings from a 2017 large geosocial networking application survey.

Sex Transm Infect 2019 Jan 5. Epub 2019 Jan 5.

European Centre for Disease Prevention and Control, Solna, Sweden.

Objective: Currently, seven European countries provide HIV pre-exposure prophylaxis (PrEP) through public health services, although there are numerous reports of off-licence use. The objective of this study was to examine current use of PrEP, likelihood of future use and indicators of potential PrEP candidacy among an opportunistic sample of men who have sex with men in Europe and Central Asia.

Methods: A survey was sent out in eight languages to users of the Hornet gay networking application in July and August 2017. Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2018-053705
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http://dx.doi.org/10.1136/sextrans-2018-053705DOI Listing
January 2019
10 Reads

Relation between infection and pelvic inflammatory disease, ectopic pregnancy and tubal factor infertility in a Dutch cohort of women previously tested for chlamydia in a chlamydia screening trial.

Sex Transm Infect 2019 Jan 3. Epub 2019 Jan 3.

Epidemiology and Surveillance Unit, Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.

Objectives: A better understanding of infection (chlamydia)-related sequelae can provide a framework for effective chlamydia control strategies. The objective of this study was to estimate risks and risk factors of pelvic inflammatory disease (PID), ectopic pregnancy and tubal factor infertility (TFI) with a follow-up time of up until 8 years in women previously tested for chlamydia in the Chlamydia Screening Implementation study (CSI) and participating in the Netherlands Chlamydia Cohort Study (NECCST).

Methods: Women who participated in the CSI 2008-2011 (n=13 498) were invited in 2015-2016 for NECCST. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053778DOI Listing
January 2019
7 Reads

Dual screen and confirm rapid test does not reduce overtreatment of syphilis in pregnant women living in a non-venereal treponematoses endemic region: a field evaluation among antenatal care attendees in Burkina Faso.

Sex Transm Infect 2018 Dec 22. Epub 2018 Dec 22.

Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.

Objectives: In resource-limited settings, screening pregnant women for syphilis using rapid diagnostic tests (RDTs) is a key tool in the prevention of congenital syphilis. However, most syphilis RDTs detect only treponemal antibodies (T-RDT), meaning antibiotics may be provided unnecessarily to previously treated pregnant women, particularly in non-venereal treponematoses endemic regions. We estimated the potential reduction in overtreatment when comparing T-RDT (SD Bioline) to a newer rapid test (Dual Path Platform (DPP) Screen and Confirm Assay, Chembio) detecting both treponemal and non-treponemal antibodies. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053722DOI Listing
December 2018

Increasing proportion of herpes simplex virus type 1 among women and men diagnosed with first-episode anogenital herpes: a retrospective observational study over 14 years in Melbourne, Australia.

Sex Transm Infect 2018 Dec 15. Epub 2018 Dec 15.

Melbourne Sexual Health Centre, Alfred Health, Carlton, Victoria, Australia.

Objectives: Reports of rising herpes simplex virus type 1 (HSV-1) genital infections relative to HSV-2 have been published up to 2006 in Australia. These changes have been attributed to declining childhood immunity to HSV-1. We described the temporal trends of HSV-1 and HSV-2 up to 2017 in Melbourne, Australia, to determine if the earlier trend is continuing. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053830DOI Listing
December 2018

Lymphogranuloma venereum presenting as an ulcer on the tongue.

Sex Transm Infect 2018 Dec 15. Epub 2018 Dec 15.

Dermatology Department, Hospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, Spain

Oropharyngeal lymphogranuloma venereum (LGV) is an uncommon presentation and mainly consists of either asymptomatic infections or enlarged cervical lymphadenopathy. According to cross-sectional studies, the prevalence of pharyngeal LGV among men who have sex with men (MSM) seems to be very low. Tissue tropism could explain the difference between rectal and oral mucosa infection frequencies. Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2018-053787
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http://dx.doi.org/10.1136/sextrans-2018-053787DOI Listing
December 2018
10 Reads

Use of geosocial networking applications is independently associated with diagnosis of STI among men who have sex with men testing for STIs: findings from the cross-sectional MSM Internet Survey Ireland (MISI) 2015.

Sex Transm Infect 2018 Dec 5. Epub 2018 Dec 5.

Health Protection Surveillance Centre, Dublin, Ireland.

Objectives: MSM Internet Survey Ireland (MISI) 2015 was an anonymous, self-completed, cross-sectional internet survey assessing sexual behaviours and health needs among men who have sex with men (MSM) in Ireland. We explored factors associated with self-reported STI diagnosis among MSM who were sexually active and had an STI test in the previous year.

Methods: We compared the study population (n=1158; 37% of total population), with the sexually active MISI population not testing for STIs (n=1620; 52% of total population). Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2018-053637
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http://dx.doi.org/10.1136/sextrans-2018-053637DOI Listing
December 2018
1 Read

Results from a cross-sectional sexual and reproductive health study among school girls in Tanzania: high prevalence of bacterial vaginosis.

Sex Transm Infect 2018 Dec 5. Epub 2018 Dec 5.

Institute of Tropical Medicine, Antwerp, Belgium.

Objectives: Bacterial vaginosis (BV) increases women's susceptibility to sexually transmitted infections (STIs) and HIV and may partly explain the high incidence of STI/HIV among girls and young women in East and southern Africa. The objectives of this study were to investigate the association between BV and sexual debut, to investigate other potential risk factors of BV and to estimate associations between BV and STIs.

Methods: Secondary school girls in Mwanza, aged 17 and 18 years, were invited to join a cross-sectional study. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053680DOI Listing
December 2018
3 Reads

Neighbourhoods, networks and pre-exposure prophylaxis awareness: a multilevel analysis of a sample of young black men who have sex with men.

Sex Transm Infect 2018 Dec 5. Epub 2018 Dec 5.

Chicago Center for HIV Elimination, Chicago, Illinois, USA.

Objective: Young black men who have sex with men (YBMSM) in the USA represent a subgroup that has the highest HIV incidence among the overall population. In the USA, pre-exposure prophylaxis (PrEP) is an effective prevention intervention to prevent HIV acquisition when taken regularly. Neighbourhood and network factors may relate to PrEP awareness, but have not been studied in YBMSM. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053639DOI Listing
December 2018

Work of the BASHH Sexual Violence Special Interest Group.

Sex Transm Infect 2018 12;94(8):552

SV SIG, BASHH, UK.

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http://dx.doi.org/10.1136/sextrans-2018-053730DOI Listing
December 2018

Human papillomavirus vaccine uptake among young gay and bisexual men who have sex with men with a time-limited targeted vaccination programme through sexual health clinics in Melbourne in 2017.

Sex Transm Infect 2018 Nov 8. Epub 2018 Nov 8.

Melbourne Sexual Health Centre, Alfred Health, Melbourne, Victoria, Australia

Objective: In mid-2017, the Victorian Government funded a free time-limited human papillomavirus (HPV) vaccination catch-up programme for gay and bisexual men who have sex with men (MSM) aged up to 26 years through sexual health clinics or other immunisation centres. We aimed to examine the uptake of the HPV vaccine among young MSM attending the Melbourne Sexual Health Centre (MSHC).

Methods: MSM aged ≤26 attending MSHC between 27 April 2017 and 31 December 2017 were included in the analysis. Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2018-053619
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http://dx.doi.org/10.1136/sextrans-2018-053619DOI Listing
November 2018
3 Reads

Working together to improve the evidence base: abridged Cochrane reviews in .

Authors:
Nicola Low

Sex Transm Infect 2019 Feb 19;95(1):2-3. Epub 2018 Oct 19.

Institute of Social and Preventive Medicine, University of Bern, Bern CH-3012, Switzerland

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http://dx.doi.org/10.1136/sextrans-2018-053762DOI Listing
February 2019

Association of interleukin-10 promoter polymorphisms with serofast state after syphilis treatment.

Sex Transm Infect 2018 Oct 19. Epub 2018 Oct 19.

Department of Dermatology, Jagiellonian University School of Medicine, Cracow, Poland.

Objectives: Recent studies suggested that upregulation of anti-inflammatory immune response during early syphilis may be associated with persistence of infection despite adequate treatment, resulting in a serofast state. The objective of this study was to determine whether enhanced interleukin (IL)-10-related response during early infection increased the risk of serofast syphilis.

Methods: Two gene promoter polymorphisms affecting IL-10 production (-1082A>G [rs1800896], -592C>A [rs1800872]) and serum levels of IL-10 were measured in 80 patients with early syphilis before and 6  months after penicillin treatment and in 24 healthy volunteers (control group). Read More

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http://dx.doi.org/10.1136/sextrans-2018-053753DOI Listing
October 2018

and HIV infection acquisition: a systematic review and meta-analysis.

Sex Transm Infect 2019 Feb 19;95(1):36-42. Epub 2018 Oct 19.

HIV/STI Reference Laboratory, Department of Clinical Sciences, Institute of Tropical Medicine, Antwerpen, Belgium.

Objectives: Trichomoniasis is the most prevalent curable STI globally, with the highest incidence and prevalence in sub-Saharan Africa (sSA). STIs have largely been associated with an increase in HIV acquisition. Our objective was to assess the existing literature available in English regarding the association of Trichomoniasis and HIV-1 acquisition. Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2018-053713
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http://dx.doi.org/10.1136/sextrans-2018-053713DOI Listing
February 2019
5 Reads

Antibiotic therapy for pelvic inflammatory disease: an abridged version of a Cochrane systematic review and meta-analysis of randomised controlled trials.

Sex Transm Infect 2019 Feb 19;95(1):21-27. Epub 2018 Oct 19.

Whittall Street Clinic, University Hospital Birmingham NHS Foundation Trust, Birmingham, UK.

Objective: To assess the effectiveness and safety of antibiotic regimens used to treat pelvic inflammatory disease (PID).

Design: This is a systematic review and meta-analysis of randomised controlled trials (RCTs). Risk of bias was assessed using the criteria outlined in the Cochrane guidelines. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053693DOI Listing
February 2019
2 Reads

Error in the calculation of person-time in the before-PrEP period by Beymer .

Sex Transm Infect 2018 11;94(7):514

Infectious Diseases, GGD Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1136/sextrans-2018-053795DOI Listing
November 2018
3 Reads

Human papillomavirus infection and associated factors for cervical intraepithelial neoplasia in women living with HIV in China: a cross-sectional study.

Sex Transm Infect 2018 Oct 18. Epub 2018 Oct 18.

National Center for Chronic and Non-communicable Disease Control and Prevention, China Center for Disease Control, Beijing, China

Objective: Women living with HIV (WLHIV) face disproportionately higher risks of acquiring human papillomavirus (HPV) compared with HIV negative counterparts. We aimed to investigate the prevalence of HPV in WLHIV in Chinese hospital setting and identify associated factors to the progression of late-stage cervical intraepithelial neoplasia (CIN2+) in this population.

Method: This retrospective study collected data from 183 WLHIV on antiretroviral treatment (ART), based on reproductive health questionnaires. Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2018-053636
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http://dx.doi.org/10.1136/sextrans-2018-053636DOI Listing
October 2018
1 Read
3.400 Impact Factor

Will an innovative connected AideSmart! app-based multiplex, point-of-care screening strategy for HIV and related coinfections affect timely quality antenatal screening of rural Indian women? Results from a cross-sectional study in India.

Sex Transm Infect 2018 Oct 15. Epub 2018 Oct 15.

Rural Unit for Health and Social Affairs (RUHSA), Christian Medical College, Vellore, Tamil Nadu, India.

Objectives: In rural pregnant Indian women, multiple missed antenatal screening opportunities due to inadequate public health facility-based screening result in undiagnosed HIV and sexually transmitted bloodborne infections (STBBIs) and conditions (anaemia). Untreated infections complicate pregnancy management, precipitate adverse outcomes and risk mother-to-child transmission. Additionally, a shortage of trained doctors, rural women's preference for home delivery and health illiteracy affect health service delivery. Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2017-053491
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http://dx.doi.org/10.1136/sextrans-2017-053491DOI Listing
October 2018
6 Reads

Prevalence and correlates of and a risk score to identify asymptomatic anorectal gonorrhoea and chlamydia infection among men who have sex with men in Kisumu, Kenya.

Sex Transm Infect 2018 Sep 21. Epub 2018 Sep 21.

Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, Washington, USA.

Objectives: In settings where laboratory capacity is limited, the WHO recommends presumptive treatment for (NG) and (CT) in asymptomatic men who have sex with men (MSM) at high risk for these infections. However, little is known about how best to target this intervention. We aimed to identify correlates of anorectal NG/CT infection in Kenyan MSM with and without anorectal symptoms and evaluate the performance of an empirical, model-based risk score to identify cases in asymptomatic men. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053613DOI Listing
September 2018
4 Reads

Sexually transmitted infections during pregnancy and subsequent risk of stillbirth and infant mortality in Kenya: a prospective study.

Sex Transm Infect 2019 Feb 18;95(1):60-66. Epub 2018 Sep 18.

Department of Global Health, University of Washington, Seattle, Washington, USA

Objectives: We evaluated the relationship of sexually transmitted infections (STIs) and genital infections during pregnancy and subsequent risk for infant mortality and stillbirth.

Methods: This was a nested longitudinal analysis using data from a study of peripartum HIV acquisition in Kenya. In the parent study, HIV-uninfected women were enrolled during pregnancy and followed until 9 months postpartum. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053597DOI Listing
February 2019
7 Reads

Microscopic examination of Gram-stained smears for anogenital gonorrhoea in men who have sex with men is cost-effective: evidence from a modelling study.

Sex Transm Infect 2019 Feb 8;95(1):13-20. Epub 2018 Sep 8.

Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.

Objective: To assess the cost-effectiveness of three testing strategies with or without light microscopic Gram-stained smear (GSS) evaluation for the detection of anogenital gonorrhoea among men who have sex with men (MSM) at the Amsterdam STI clinic using a healthcare payer perspective.

Methods: Three testing strategies for MSM were compared: (1) GSS in symptomatic MSM only (currently practised strategy), (2) no GSS and (3) GSS in symptomatic and asymptomatic MSM. The three testing protocols include testing with nucleic acid amplification test to verify the GSS results in (1) and (3), or as the only test in (2). Read More

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http://dx.doi.org/10.1136/sextrans-2018-053578DOI Listing
February 2019
18 Reads

Does infection with induce long-lasting partial immunity? Insights from mathematical modelling.

Sex Transm Infect 2018 Sep 4. Epub 2018 Sep 4.

Infectious Disease Epidemiology Group, Weill Cornell Medicine-Qatar, Cornell University, Qatar Foundation - Education City, Doha, Qatar.

Objectives: To explore whether existence of long-lasting partial immunity against reinfection with is necessary to explain prevalence patterns by age and sexual risk, and to provide a plausible estimate for the effect size, defined here as a reduction in susceptibility to reinfection.

Methods: A population-based mathematical model was constructed to describe natural history and transmission dynamics by age and sexual risk. The model was parameterised using natural history, and epidemiological and sexual behaviour data, and applied for UK and US data. Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2018-053543
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http://dx.doi.org/10.1136/sextrans-2018-053543DOI Listing
September 2018
13 Reads
3.401 Impact Factor

Cross-sectional study of urethral exposures at last sexual episode associated with non-gonococcal urethritis among STD clinic patients.

Sex Transm Infect 2018 Sep 4. Epub 2018 Sep 4.

Department of Epidemiology, University of Washington, Seattle, Washington, USA.

Objective: Although (CT) and (MG) are major causes of non-gonococcal urethritis (NGU), up to 50% of cases are of unknown aetiology. We sought to identify urethral exposures at last sexual episode associated with NGU and non-CT/non-MG NGU to identify anatomical sites from which aetiologically relevant micro-organisms may be acquired.

Methods: We enrolled STD clinic patients with and without NGU assigned male sex at birth and age ≥16 into a cross-sectional study. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053634DOI Listing
September 2018
13 Reads

Are associations between HIV and human papillomavirus transmission due to behavioural confounding or biological effects?

Sex Transm Infect 2018 Aug 31. Epub 2018 Aug 31.

Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa.

Objectives: Cohort studies have shown significant increased risk of HIV acquisition following human papillomavirus (HPV) detection and increased risk of new HPV detection in individuals with HIV infection, after adjusting for behavioural risk factors. This study uses an individual-based model to assess whether confounding sexual behaviour factors and network level effects can explain these associations between HIV and HPV infection status, without biological interactions.

Methods: The model simulates infection with 13 oncogenic HPV types and HIV. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053558DOI Listing
August 2018
11 Reads

Legislation and regulation in the era of online sexual health: how do we ensure provision of safe, high-quality care?

Sex Transm Infect 2018 12 31;94(8):550-551. Epub 2018 Aug 31.

School of Health and Life Science, Glasgow Caledonian University, Glasgow, UK.

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http://dx.doi.org/10.1136/sextrans-2018-053679DOI Listing
December 2018
9 Reads

Foster care, syndemic health disparities and associations with HIV/STI diagnoses among young adult substance users.

Sex Transm Infect 2018 Aug 31. Epub 2018 Aug 31.

Center for Applied Research on Substance Use and Health Disparities, Nova Southeastern University, Fort Lauderdale, Florida, USA.

Objectives: Foster care history is associated with many health and social problems, including sexual risk behaviours, HIV and other sexually transmitted infections (STIs). This cross-sectional study compares sexual risk behaviours among a sample of young adult substance users in Miami (N=602) with and without foster care histories.

Methods: Participants completed a comprehensive assessment which included sections on foster care, sexual risk behaviours and related health and social problems. Read More

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http://dx.doi.org/10.1136/sextrans-2017-053490DOI Listing
August 2018
1 Read

Usage of purchased self-tests for HIV infections among migrants living in the UK, France and the Netherlands: a cross-sectional study.

Sex Transm Infect 2018 Aug 31. Epub 2018 Aug 31.

Department of Infectious Diseases Research and Prevention, Public Health Service of Amsterdam, Amsterdam, The Netherlands.

Objectives: Self-tests are performed and interpreted autonomously by a person without involving a healthcare professional or a certified laboratory. To gain insight into the usage of purchased HIV self-tests (HIVST) among migrants living in high-income countries, we studied the prevalence and determinants of HIVST usage among migrants living in the UK, France and the Netherlands.

Methods: We used web-based questionnaire data collected between April 2014 and July 2015 among migrants living in the UK, France and the Netherlands who participated in the cross-sectional community survey of the aMASE (advancing Migrant Access to health Services in Europe) study. Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2018-053583
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http://dx.doi.org/10.1136/sextrans-2018-053583DOI Listing
August 2018
1 Read

Aptima assay elucidates significant underdiagnosis of trichomoniasis among women in Brazil according to an observational study.

Sex Transm Infect 2018 Aug 28. Epub 2018 Aug 28.

WHO Collaborating Centre for Gonorrhoea and other STIs, Department of Laboratory Medicine, Faculty of Medicine and Health, Örebro University, Örebro, Sweden

Objectives: (TV) infection is the most common non-viral STI globally and can result in adverse pregnancy outcomes and exacerbated HIV acquisition/transmission. Nucleic acid amplification tests (NAATs) are the most sensitive diagnostic tests, with high specificity, but TV NAATs are rarely used in Brazil. We investigated the TV prevalence and compared the performance of the US Food and Drug Association-cleared Aptima TV assay with microscopy (wet mount and Gram-stained) and culture for TV detection in women in Pelotas, Brazil in an observational study. Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2018-053635
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http://dx.doi.org/10.1136/sextrans-2018-053635DOI Listing
August 2018
14 Reads

Sexually transmitted infections in the Delta Regional Authority: significant disparities in the 252 counties of the eight-state Delta Region Authority.

Sex Transm Infect 2018 12 27;94(8):611-615. Epub 2018 Aug 27.

Department of Applied Health, Southern Illinois University Edwardsville, Edwardsville, Illinois, USA.

Objective: Chlamydia, gonorrhoea and syphilis (primary and secondary) are at high levels in the USA. Disparities by race, gender and sexual orientation have been characterised, but while there are indications that rural poor populations may also be at distinct risk this has been subjected to little study by comparison. The federally designated Delta Regional Authority, similar in structure to the Appalachian Regional Commission, oversees 252 counties within eight Mississippi Delta states experiencing chronic economic and health disparities. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053556DOI Listing
December 2018
1 Read

Club drug users had higher odds of reporting a bacterial STI compared with non-club drug users: results from a cross-sectional analysis of gay and bisexual men on HIV pre-exposure prophylaxis.

Sex Transm Infect 2018 Aug 20. Epub 2018 Aug 20.

Department of Community Health and Social Sciences, CUNY Graduate School of Public Health and Health Policy, New York, USA

Objectives: Pre-exposure prophylaxis (PrEP) can reduce HIV transmission risk for many gay, bisexual and other men who have sex with men. However, bacterial STI (BSTI) associated with decreasing condom use among HIV PrEP users is a growing concern. Determining the characteristics of current PrEP users at highest BSTI risk fills a critical gap in the literature. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053591DOI Listing

Bridging the HIV-syphilis testing gap: dual testing among men who have sex with men living in China.

Sex Transm Infect 2018 Aug 20. Epub 2018 Aug 20.

Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK

Objectives: The WHO recommends dual testing for HIV and syphilis among key populations, including men who have sex with men (MSM). We assessed the proportion of men who had dual tested and reasons for not dual testing.

Methods: In 2017, an online survey of MSM was conducted in eight cities from two provinces in China. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053527DOI Listing
August 2018
5 Reads
3.401 Impact Factor