4,898 results match your criteria Sexually Transmitted Diseases[Journal]


High Interest in Doxycycline for Sexually Transmitted Infection Postexposure Prophylaxis in a Multicity Survey of Men Who Have Sex With Men Using a Social Networking Application.

Sex Transm Dis 2019 Apr;46(4):e32-e34

Bridge HIV, San Francisco Department of Public Health.

Current strategies to prevent sexually transmitted infections (STIs) are not controlling the epidemic. The efficacy of doxycycline STI postexposure prophylaxis shows promise in pilot studies, but wider acceptability is unknown. A majority (84%) of diverse individuals using a gay social networking application were interested in doxycycline STI postexposure prophylaxis. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000942DOI Listing

Human Immunodeficiency Virus Diagnosis After a Syphilis, Gonorrhea, or Repeat Diagnosis Among Males Including non-Men Who Have Sex With Men: What Is the Incidence?

Sex Transm Dis 2019 Apr;46(4):271-277

Department of Medicine, Johns Hopkins School of Medicine.

Background: The release of the first drug for human immunodeficiency virus (HIV) preexposure prophylaxis (PrEP) in 2012 marked the beginning of a new era of HIV prevention. Although PrEP is highly efficacious, identifying and ultimately increasing uptake among the highest risk male subgroups remains a challenge.

Methods: Public health surveillance data from 2009 to 2016 was used to evaluate the risk of an HIV diagnosis after a syphilis (ie, primary, secondary, or early latent), gonorrhea, and repeat diagnoses among urban males, including men who have sex with men (MSM) and non-MSM in Baltimore City. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000964DOI Listing

Integrating Human Immunodeficiency Virus Testing Into Syphilis Partner Services in Mississippi to Improve Human Immunodeficiency Virus Case Finding.

Sex Transm Dis 2019 Apr;46(4):240-245

Colorado Department of Public Health and Environment, Denver, CO.

Background: Mississippi has the 10th highest rate of new human immunodeficiency virus (HIV) infections in the United States. The Mississippi State Department of Health (MSDH) integrated partner HIV testing into syphilis partner services (PS) in 2014, but the effectiveness of this as an HIV case finding strategy has not been evaluated.

Methods: We identified all early syphilis (primary, secondary, and early latent) case records reported from July 1, 2014, to December 31, 2016, excluding case records for people concurrently newly diagnosed with HIV. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000951DOI Listing

Rapidly Spreading Human Immunodeficiency Virus Epidemic Among Older Males and Associated Factors: A Large-scale Prospective Cohort Study in Rural Southwest China.

Sex Transm Dis 2019 Apr;46(4):234-239

State Key Laboratory of Infectious Disease Prevention and Control (SKLID), Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention (China CDC), Beijing, China.

Background: Increasing risk of human immunodeficiency virus (HIV) heterosexual transmission can raise the potential for a more diffuse and generalized epidemic. In response to the paucity of data on HIV incidence among heterosexuals in China, we conducted a large-scale, population-based cohort study located in rural southwest China.

Methods: Baseline enrollment for the study was conducted from 2013 to 2014 and follow-up at 12 months was from 2014 to 2015 among adults 20 years or older in 3 rural counties of Southwest China. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000957DOI Listing

Incidence, Clearance, and Persistence of Anal Human Papillomavirus in Men Who Have Sex With Men Living With Human Immunodeficiency Virus: Implications for Human Papillomavirus Vaccination.

Sex Transm Dis 2019 Apr;46(4):229-233

The Centre Clinic, Victorian AIDS Council, St Kilda, Victoria, Australia.

Background: Men who have sex with men living with human immunodeficiency virus have a high risk of anal cancer. We estimate the likely benefit of human papillomavirus (HPV) vaccination among participants of the Anal Cancer Examination study.

Methods: Anal swabs were collected for the detection and genotyping of anal HPV DNA by linear array (Roche Diagnostics) in this 2-year multicenter prospective cohort. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000958DOI Listing

Monitoring HIV Preexposure Prophylaxis Use Among Men Who Have Sex With Men in Washington State: Findings From an Internet-Based Survey.

Sex Transm Dis 2019 Apr;46(4):221-228

Department of Epidemiology and Biostatistics, University at Albany School of Public Health, State University of New York, Rensselaer, NY.

Background: Many state and local health departments now promote and support the use of HIV preexposure prophylaxis (PrEP), yet monitoring use of the intervention at the population level remains challenging.

Methods: We report the results of an online survey designed to measure PrEP use among men who have sex with men (MSM) in Washington State. Data on the proportion of men with indications for PrEP based on state guidelines and levels of awareness, interest, and use of PrEP are presented for 1080 cisgender male respondents who completed the survey between January 1 and February 28, 2017. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000965DOI Listing
April 2019
1 Read

Standards for Treatment and Control Regimens in Therapeutic Trials for Gonorrhea: Lessons From a "Failed" Trial.

Sex Transm Dis 2019 Mar 11. Epub 2019 Mar 11.

From the Center for AIDS and STD and the Division of Infectious Disease, Department of Medicine, University of Washington, Seattle, Washington; and the Division of Infectious Diseases, Department of Medicine, Johns Hopkins Bayview Medical Center, Baltimore, Maryland.

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http://dx.doi.org/10.1097/OLQ.0000000000000994DOI Listing

Characteristics of gay, bisexual and other men who have sex with men with multiple diagnoses of infectious syphilis in British Columbia, Canada, 2005 to 2014.

Sex Transm Dis 2019 Mar 11. Epub 2019 Mar 11.

British Columbia Centre for Disease Control.

Background: Infectious syphilis has increased substantially over the past decade. Targeting limited public health resources towards subpopulations with multiple re-infections may have a large impact in reducing onward transmission within a community.

Methods: A chart review was conducted for individuals with ≥4 infectious syphilis diagnoses between 2005 and 2014 (the top 1% of all syphilis diagnoses in British Columbia, Canada). Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000995DOI Listing
March 2019
1 Read
2.842 Impact Factor

Evaluation of a rapid syphilis test in an emergency department setting in Detroit, Michigan.

Sex Transm Dis 2019 Mar 4. Epub 2019 Mar 4.

Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA.

Background: Syphilis transmission can be prevented by prompt diagnosis and treatment of primary and secondary infection. We evaluated the performance of a point-of-care rapid syphilis treponemal test (RST) in an emergency department (ED) setting.

Methods: Between June 2015 and April 2016, men aged 18-34 years seeking services in a Detroit ED, and with no history of syphilis, were screened for syphilis with the RST, rapid plasma reagin (RPR) test, and Treponema pallidum particle agglutination assay (TP-PA). Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000993DOI Listing
March 2019
3 Reads

Gaps in chlamydia treatment within California family planning clinics: Are patients filling prescriptions?

Sex Transm Dis 2019 Feb 26. Epub 2019 Feb 26.

Sexually Transmitted Disease Control Branch, Division of Communicable Disease Control, Center for Infectious Diseases, California Department of Public Health, Richmond, California.

Background: Compared with receiving medication dispensed in a health center, patients receiving prescriptions must take additional steps for treatment. Few clinics have protocols for ensuring prescriptions are filled. This study evaluated prescription fill rates for chlamydia treatment based on claims data in California Title X clinics, and examined fill rates by patient demographics and clinic type. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000991DOI Listing
February 2019

Incidence, persistence, clearance and correlates of genital human papillomavirus infection and anogenital warts in a cohort of men living with HIV South Africa.

Sex Transm Dis 2019 Feb 20. Epub 2019 Feb 20.

Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Objective: To estimate the incidence; persistence and correlates of HPV infection and anogenital warts (AGW) among men living with HIV (MLHIV).

Methods: Overall, 304 MLHIV ≥18 years were enrolled and attended follow-up visits at 6, 12 and 18 months. Clinicians examined for AGW, collected blood, and penile swabs for HPV testing (Roche Linear Array) at each visit. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000979DOI Listing
February 2019
1 Read

An evaluation of sexually transmitted infection and odds of preterm or early term birth using propensity score matching.

Sex Transm Dis 2019 Feb 11. Epub 2019 Feb 11.

California Preterm Birth Initiative, University of California San Francisco, San Francisco, California, USA.

Background: Few studies have examined the relationship between sexually transmitted infections (STIs) and preterm birth (<37 weeks gestation) by subtype (<32 weeks, 32 - 36 weeks, spontaneous, provider-initiated). Here, we evaluate the odds of preterm (by subtype) and early term (37 and 38 weeks gestation) birth in women with an STI compared to a propensity score matched reference population.

Methods: The sample was selected from California births in 2007-2012. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000985DOI Listing
February 2019
2 Reads

The prevalence of Mycoplasma genitalium and association with HIV infection in symptomatic patients, Johannesburg, South Africa, 2007-2014.

Sex Transm Dis 2019 Feb 11. Epub 2019 Feb 11.

Centre for HIV & STIs, National Institute for Communicable Diseases, National Health Laboratory Service, Johannesburg, South Africa.

Background: Mycoplasma genitalium is associated with genital discharge syndrome, but limited prevalence data is available in South Africa. The prevalence rates of M. genitalium infection and HIV co-infection were determined in urogenital specimens collected from male and female patients presenting with genital discharge syndrome to a primary health care centre in Johannesburg, South Africa from 2007 through 2014. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000984DOI Listing
February 2019
2 Reads

What is the Evidence for the Sexual Transmission of Syphilis from Asymptomatic Persons?

Sex Transm Dis 2019 Feb 9. Epub 2019 Feb 9.

Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1097/OLQ.0000000000000987DOI Listing
February 2019
1 Read

Increasing syphilis detection among patients assigned male at birth screened at a Boston community health center specializing in sexual and gender minority health, 2005-2015.

Sex Transm Dis 2019 Feb 9. Epub 2019 Feb 9.

The Fenway Institute, Fenway Health, Boston, MA.

For patients assigned male at birth seen at a Boston clinic over a decade, we found disproportionate syphilis cases in young patients, Black and Hispanic/Latinx patients, gay/bisexual patients, cisgender men, and those with new or chronic HIV infection; syphilitic reinfections have significantly increased.

Abstract Background: United States syphilis rates have increased to levels last seen in the 1990s. We examined syphilis epidemiology of patients attending a Boston community health center specializing in sexual and gender minority health. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000986DOI Listing
February 2019
6 Reads

Presumptive and Follow-up Treatment for Gonorrhea and Chlamydia Among Patients Attending Public Health Department Clinics in Virginia, 2016.

Sex Transm Dis 2019 Mar;46(3):199-205

Background: Presumptive antibiotic treatment is common for suspected chlamydia (CT) and gonorrhea (GC) infections before laboratory confirmation to prevent complications, reduce loss-to-follow-up, and interrupt transmission. We assessed this practice in sexually transmitted disease (STD) and family planning clinics.

Methods: We performed a retrospective analysis of data from clinics in Virginia in 2016 using administrative data merged with electronic laboratory reporting data. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000922DOI Listing
March 2019
1 Read

Reimagining Health Communication: A Noninferiority Randomized Controlled Trial of Crowdsourced Intervention in China.

Sex Transm Dis 2019 Mar;46(3):172-178

Sc Rutgers University, Newark, NJ.

Background: Crowdsourcing, the process of shifting individual tasks to a large group, may be useful for health communication, making it more people-centered. We aimed to evaluate whether a crowdsourced video is noninferior to a social marketing video in promoting condom use.

Methods: Men who have sex with men (≥16 years old, had condomless sex within 3 months) were recruited and randomly assigned to watch 1 of the 2 videos in 2015. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380681PMC
March 2019
2.842 Impact Factor

Get Yourself Tested (GYT) goes to High School: Adapted STD Prevention Campaign and Associated Student Use of Clinic STD Testing Services.

Sex Transm Dis 2019 Feb 6. Epub 2019 Feb 6.

ICF.

Background: In an attempt to increase high school students' STD testing ratesrates, the Centers for Disease Control and Prevention's Division of Adolescent and School Health partnered with ICF and Chicago Public Schools (CPS) to adapt and implement the "GYT: Get Yourself Tested" health marketing campaign for a high school.

Methods: Clinic record data and student retrospective self-report surveys (n=193) tested for differences between the GYT intervention school and a comparison school on a number of outcomes including HIV and STD testing.

Results: Clinic record data showed that testing increased significantly more for the intervention than the comparison school during the GYT implementation period (B = 2. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000983DOI Listing
February 2019

Concurrent and time-lagged effects of social disorganization on chlamydia rate trajectories among United States counties and the District of Columbia, 2010-2015.

Sex Transm Dis 2019 Jan 30. Epub 2019 Jan 30.

Department of Epidemiology, Robert Stempel College of Public Health and Social Work, Florida International University, Miami, FL.

Objective: To examine the longitudinal relationship between social disorganization (SD) and genital Chlamydia trachomatis infection.

Methods: US county-level data for 2010-2015 were used. Reliability and principal component analysis revealed two SD factors: socioeconomic deprivation and demographic instability. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000982DOI Listing
January 2019
2 Reads
2.842 Impact Factor

Genetic stability of the typing loci used in the multilocus sequence typing and enhanced CDC typing of syphilis treponemes.

Sex Transm Dis 2019 Jan 30. Epub 2019 Jan 30.

Department of Biology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.

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http://dx.doi.org/10.1097/OLQ.0000000000000981DOI Listing
January 2019
1 Read

HIV incidence among women at high risk of HIV infection attending a dedicated clinic in Kampala, Uganda: 2008-2017.

Sex Transm Dis 2019 Jan 19. Epub 2019 Jan 19.

MRC Tropical Epidemiology Group, London School of Hygiene and Tropical Medicine (LSHTM), UK.

Background: High attrition and irregular testing for HIV in cohort studies for high-risk populations can bias incidence estimates. We compare incidence trends for high-risk women attending a dedicated HIV prevention and treatment clinic, using common methods for assigning when seroconversion occurs and whether seroconversion occurs among those with attrition.

Methods: Between April 2008-May 2009 women were enrolled into cohort-1 and from January 2013 into cohort-2, then scheduled for follow-up once every three months. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000978DOI Listing
January 2019
4 Reads

Proportion of Incident HIV Cases among Men Who Have Sex with Men Attributable to Gonorrhea and Chlamydia: A Modeling Analysis.

Sex Transm Dis 2019 Jan 19. Epub 2019 Jan 19.

Department of Epidemiology, Emory University, Atlanta, Georgia.

Background: Sexually transmitted infections (STIs) are associated with an increased risk of HIV acquisition and transmission. We estimated the proportion of HIV incidence among men who have sex with men attributable to infection with the two most common bacterial STIs, Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT).

Methods: We used a stochastic, agent-based model of a sexual network of MSM with co-circulating HIV, NG, and CT infections. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000980DOI Listing
January 2019
1 Read
2.842 Impact Factor

Efficacy and safety of single dose oral delafloxacin compared with intramuscular ceftriaxone for uncomplicated gonorrhea treatment: an open-label, non-inferiority, Phase 3, multicenter, randomized study.

Sex Transm Dis 2019 Jan 19. Epub 2019 Jan 19.

Melinta Therapeutics, Lincolnshire.

Background: We evaluated single oral dose delafloxacin versus single intramuscular (IM) ceftriaxone in participants with uncomplicated urogenital gonorrhea (primary objective). Secondary objectives included the efficacy, safety, and tolerability of delafloxacin versus ceftriaxone for uncomplicated urogenital, rectal, and/or pharyngeal gonorrhea.

Methods: In this open-label, multicenter study, 460 participants at 25 study centers were randomized (2:1) to receive a single 900mg oral dose of delafloxacin or 250mg IM ceftriaxone. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000971DOI Listing
January 2019
1 Read

Decision Readiness to Disclose HIV-Positive Status to Family Members.

Sex Transm Dis 2019 Jan 19. Epub 2019 Jan 19.

University of South Florida, College of Behavioral and Community Sciences, Department of Mental Health Law and Policy, Tampa, FL.

Background: People living with HIV (PLWH) are faced with the often difficult decision of whether, when, and how to disclose their seropositive status. This study draws on the transtheoretical model of change to examine men and women's decision readiness to disclose their HIV-positive status to family members and to assess predictors (decisional balance and decision self-efficacy) of their decision readiness.

Methods: Cross-sectional data were collected from 346 PLWH - 191 males and 155 females. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000966DOI Listing
January 2019

Extragenital Gonorrhea and Chlamydia Among Men and Women According to Type of Sexual Exposure.

Sex Transm Dis 2019 Jan 19. Epub 2019 Jan 19.

Department of Biomedical & Health Informatics, University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA.

Background: Current guidelines recommend screening for extragenital gonorrhea (GC) and chlamydia (CT) only among men having sex with men (MSM). Extragenital GC and CT is associated with treatment failure and disease transmission. The prevalence of exragenital GC/CT infections in women and in men having sex with women (MSW) are less well studied. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000967DOI Listing
January 2019
3 Reads

Monitoring HIV pre-exposure prophylaxis use among men who have sex with men in Washington State: findings from an internet-based survey.

Sex Transm Dis 2019 Jan 19. Epub 2019 Jan 19.

Departments of Epidemiology.

Background: Many state and local health departments now promote and support the use of HIV pre-exposure prophylaxis (PrEP), yet monitoring use of the intervention at the population level remains challenging.

Methods: We report the results of an online survey designed to measure PrEP use among men who have sex with men (MSM) in Washington State. Data on the proportion of men with indications for PrEP based on state guidelines and levels of awareness, interest, and use of PrEP are presented for 1,080 cisgender male respondents who completed the survey between January 1 and February 28, 2017. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000965DOI Listing
January 2019

Prevalence, Macrolide Resistance, and Fluoroquinolone Resistance in Mycoplasma genitalium in Men Who Have Sex With Men Attending an Sexually Transmitted Disease Clinic in Dublin, Ireland in 2017-2018.

Sex Transm Dis 2019 Apr;46(4):e35-e37

Department of Virology, St James's Hospital, Dublin, Ireland.

This is the first prevalence study of Mycoplasma genitalium and antimicrobial resistance study in Ireland. In urine samples from men who have sex with men (n = 400) attending a sexually transmitted disease clinic in Dublin, the prevalence of M. genitalium was 3% (12 of 400 specimens; 95% confidence interval, 1. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000940DOI Listing
April 2019
1 Read

Resistance Profile of Neisseria gonorrhoeae in KwaZulu-Natal, South Africa Questioning the Effect of the Currently Advocated Dual Therapy.

Sex Transm Dis 2019 Apr;46(4):266-270

Background: We report on the antimicrobial resistance profile of Neisseria gonorrhoeae isolates and the distribution of tetM genes in isolates with high-level tetracycline resistance in KwaZulu-Natal, South Africa.

Methods: Male and female patients presenting with urethral and/or vaginal discharge were recruited into the study. Urethral and cervical secretions were cultured on New York City agar. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000961DOI Listing
April 2019
1 Read
2.842 Impact Factor

Is It Time to Stop Using Single Dose Oral Metronidazole for the Treatment of Trichomoniasis in Women?

Sex Transm Dis 2018 Dec 5. Epub 2018 Dec 5.

Tulane University School of Public Health and Tropical Medicine - Department of Epidemiology.

The 2015 Centers for Disease Control STD Treatment Guidelines currently recommend a single 2-gram dose of oral metronidazole (MTZ) as the preferred regimen for treatment of trichomoniasis in HIV-negative women. Mounting recent evidence has shown that the 7-day oral MTZ dosing regimen is more efficacious than the single 2-gram dose. This commentary reviews the implications associated with these new data and discusses issues surrounding it that should be considered moving forward. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000959DOI Listing
December 2018

Evaluation of an Adapted Project Connect Community-based Intervention Among Professionals Serving Young Minority Men.

Sex Transm Dis 2019 Mar;46(3):165-171

Pediatrics and.

Background: To address sexual and reproductive health (SRH) needs of young minority urban males, we developed and evaluated Project Connect Baltimore (Connect), which was adapted from a program with demonstrated effectiveness among young females. The objectives were to determine (1) the feasibility of Connect as adapted for young minority men, (2) whether the program increased SRH knowledge and resource sharing of youth-serving professionals (YSPs) working with young men, and (3) whether the program improved awareness and use of resources for young minority men in Baltimore City, an urban environment with high rates of sexually transmitted diseases.

Methods: Connect developed a clinic referral guide for male youth-friendly resources for SRH. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000977DOI Listing
March 2019
5 Reads

Incidence and Characteristics of Neonatal Herpes: Comparison of Two Population-Based Data Sources, New York City, 2006-2015.

Sex Transm Dis 2019 Feb;46(2):125-131

Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, U.S. Centers for Disease Control and Prevention, Atlanta, GA.

Background: Neonatal herpes (nHSV) is a potentially fatal disease caused by herpes simplex virus (HSV) infection during the neonatal period. Neonatal herpes simplex virus infections are not nationally notifiable, and varying incidence rates have been reported. Beginning in 2006, New York City (NYC) required reporting of nHSV infections and conducted case investigations. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000923DOI Listing
February 2019
1 Read

Clinical Features and Therapeutic Response in Women Meeting Criteria for Presumptive Treatment for Pelvic Inflammatory Disease Associated With Mycoplasma genitalium.

Sex Transm Dis 2019 Feb;46(2):73-79

Centre for Epidemiology and Biostatistics, Melbourne School of Population & Global Health, University of Melbourne, Parkville, Victoria, 3010, Australia.

Background: There are limited published data describing clinical features and therapeutic response in women meeting the criteria for presumptive treatment of pelvic inflammatory disease associated with Mycoplasma genitalium (MG-PID). The MG-PID has been reported to respond poorly to standard PID treatment regimens and while moxifloxacin is recommended in several treatment guidelines, published data to support its use are scant.

Methods: We conducted a retrospective study of women at Melbourne Sexual Health Centre between 2006 and 2017, who met the Centers for Disease Control and Prevention criteria for presumptive treatment of PID, and had MG detected as the sole pathogen. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000924DOI Listing
February 2019
11 Reads

Associations Between Cannabis Use, Sexual Behavior, and Sexually Transmitted Infections/Human Immunodeficiency Virus in a Cohort of Young Men Who Have Sex With Men.

Sex Transm Dis 2019 Feb;46(2):105-111

From the Department of Epidemiology, Fielding School of Public Health.

Background: Among men who have sex with men (MSM) the relationship between sexually transmitted infections (STIs) and cannabis use is not well established. We assessed cannabis use, sexual behavior, and STIs including human immunodeficiency virus (HIV) in a diverse cohort of young MSM.

Methods: In Los Angeles, the mSTUDY cohort conducted visits every 6 months with 512 MSM between 2014 and 2017 collecting demographics, sexual behaviors, and reports of frequency of substance use. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342487PMC
February 2019
2 Reads

Delay in Seeking Healthcare Services Following Onset of Urethritis Symptoms in Men.

Sex Transm Dis 2019 Jan 10. Epub 2019 Jan 10.

Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL.

Background: Symptom awareness, behavioral factors, and other barriers associated with timely STI healthcare provision in men is not well-studied.

Methods: Men attending an STI clinic answered a questionnaire regarding their symptoms, sexual behavior, and socio-demographic and behavioral characteristics. Characteristics of symptomatic men were compared between those who did and did not delay seeking healthcare services. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000976DOI Listing
January 2019
6 Reads

Hormonal contraceptives and the acquisition of sexually transmitted infections: an updated systematic review.

Sex Transm Dis 2019 Jan 8. Epub 2019 Jan 8.

City University of New York, Graduate School of Public Health & Health Policy, New York, USA.

Background: Evidence suggests that some forms of hormonal contraception (HC) increase women's risk of non-HIV sexually transmitted infections (STIs), yet evidence has not been reviewed since 2008. We conducted an updated systematic review to incorporate studies published between January 2009 and June 2017 to examine the relationship between HCs and incident and/or recurrent STIs.

Methods: We searched PubMed and EMBASE to identify prospective studies comparing risk of Chlamydia trachomatis, Neisseria gonorrhoeae, human papillomavirus (HPV), herpes simplex virus type 2 (HSV-2), Treponema pallidum, or Trichomonas vaginalis, between women using HC vs. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000975DOI Listing
January 2019
1 Read

Performance of the Syphilis Health Check in Clinic and Laboratory-Based Settings.

Sex Transm Dis 2019 Apr;46(4):250-253

Association of Public Health Laboratories, Silver Spring, MD.

Background: In this study, we evaluate the performance of the Syphilis Health Check (SHC) in clinical and laboratory settings using fingerstick whole blood and serum.

Methods: Fingerstick whole blood and serum specimens from adult patients (n = 562) without prior syphilis history presenting at 2 county health department STD clinics in North Carolina were tested. Fingerstick specimens were tested with the SHC in clinic, and serum specimens were tested at the North Carolina State Laboratory of Public Health with: (1) qualitative rapid plasma reagin, (2) treponemal EIA, and (3) SHC. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000974DOI Listing

High Global Burden and Costs of Bacterial Vaginosis: A Systematic Review and Meta-Analysis.

Sex Transm Dis 2019 Jan 7. Epub 2019 Jan 7.

Department of Epidemiology, University of Washington, Seattle, WA.

Background: Bacterial vaginosis (BV) is the most common vaginal infection among women of reproductive age and is associated with important adverse health outcomes. Estimates of the burden of BV and associated costs are needed to inform research priorities.

Methods: We conducted a systematic review and meta-analysis of global BV prevalence among reproductive-aged women in the general population. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000972DOI Listing
January 2019
3 Reads

Improving Tracking of Post-Discharge Results of Sexually Transmitted Infection Screening Tests in Hospitalized Adolescents and Young Adults: a Quality Improvement Initiative.

Sex Transm Dis 2019 Jan 7. Epub 2019 Jan 7.

Division of Pediatric Hospitalist Medicine, Department of Pediatrics, Children's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, New York.

Hospitalizations offer chlamydia and gonorrhea screening opportunities for youth who may not seek preventive care. Tracking of screening test results still pending after hospital discharge is an important component of clinical care. This process can be improved by protocol use and enhanced by effective, automated electronic health record tools. Read More

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http://Insights.ovid.com/crossref?an=00007435-900000000-9813
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http://dx.doi.org/10.1097/OLQ.0000000000000973DOI Listing
January 2019
9 Reads

Recent Developments in Biomedical Issues in Sexually Transmitted Infections: Implications for Behavioral Parameters of Interest.

Sex Transm Dis 2018 Dec 28. Epub 2018 Dec 28.

Division of Infectious Diseases, University of Alabama at Birmingham School of Medicine, Birmingham, AL.

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http://dx.doi.org/10.1097/OLQ.0000000000000969DOI Listing
December 2018

ACCURACY OF mRNA HPV TESTS FOR DIAGNOSTIC TRIAGE OF MINOR CYTOLOGICAL CERVICAL LESIONS: A SYSTEMATIC REVIEW AND META-ANALYSIS.

Sex Transm Dis 2018 Dec 28. Epub 2018 Dec 28.

Translational Biomedicine Laboratory, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, SC, Brazil.

Objectives: The main objective of this systematic review and meta-analysis is to specify the accuracy of mRNA HPV tests among women with previous minor cervical lesion cytology to detect high-grade squamous intra-epithelial lesions (CIN2+ and CIN3+), comparing to a histopathological reference standard. The secondary objective is to compare mRNA HPV tests accuracies and the DNA hrHPV test among these women.

Methods: Eligible studies were identified by searching the electronic databases with medical subject headings (MeSH). Read More

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http://Insights.ovid.com/crossref?an=00007435-900000000-9813
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http://dx.doi.org/10.1097/OLQ.0000000000000970DOI Listing
December 2018
5 Reads

Optimal timing for Trichomonas vaginalis test of cure using nucleic acid amplification testing.

Sex Transm Dis 2018 Dec 28. Epub 2018 Dec 28.

Tulane School of Public Health and Tropical Medicine, Department of Epidemiology, New Orleans, United States.

Background: The optimal timing for nucleic acid amplification testing (NAAT) post-treatment for Trichomonas vaginalis has not been fully established. Testing too soon post-treatment may detect remnant nucleic acid that is not from viable organisms, falsely misclassifying person as infected. The purpose of this study was to examine how long T. Read More

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http://Insights.ovid.com/crossref?an=00007435-900000000-9813
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http://dx.doi.org/10.1097/OLQ.0000000000000968DOI Listing
December 2018
1 Read

Low Chlamydia and Gonorrhea Testing Rates Among Men Who Have Sex With Men in Guangdong and Shandong Provinces, China.

Sex Transm Dis 2019 Apr;46(4):260-265

Department of Social and Behavior Health Sciences, Rutgers School of Public Health, Piscataway, NJ.

Background: Although periodic chlamydia and gonorrhea testing is recommended for men who have sex with men (MSM), little is known about testing rates in China. This study examines chlamydia and gonorrhea testing rates and testing correlates among Chinese MSM.

Methods: An online survey of MSM was conducted in August 2017. Read More

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http://Insights.ovid.com/crossref?an=00007435-900000000-9813
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http://dx.doi.org/10.1097/OLQ.0000000000000963DOI Listing
April 2019
2 Reads
2.842 Impact Factor

From Safety Net Providers to Centers of Excellence The Future of Publicly-Funded STI Clinics in the U.S.

Sex Transm Dis 2018 Dec 7. Epub 2018 Dec 7.

Rietmeijer Consulting, LLC, 533 Marion Street, Denver, Colorado 80218. Email:

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http://dx.doi.org/10.1097/OLQ.0000000000000962DOI Listing
December 2018

HIV DIAGNOSIS FOLLOWING A SYPHILIS, GONORRHEA, OR REPEAT DIAGNOSIS AMONG MALES INCLUDING NON-MSM: WHAT IS THE INCIDENCE?

Sex Transm Dis 2018 Dec 13. Epub 2018 Dec 13.

Center for Child and Community Health Research (CCHR), Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD, USA.

Background: The release of the first drug for HIV pre-exposure prophylaxis (PrEP) in 2012 marked the beginning of a new era of HIV prevention. Although PrEP is highly efficacious, identifying and ultimately increasing uptake among the highest risk male subgroups remains a challenge.

Methods: Public health surveillance data from 2009-2016 was used to evaluate the risk of an HIV diagnosis following a syphilis (i. Read More

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http://Insights.ovid.com/crossref?an=00007435-900000000-9814
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http://dx.doi.org/10.1097/OLQ.0000000000000964DOI Listing
December 2018
21 Reads

External Reviewers.

Authors:

Sex Transm Dis 2019 Jan;46(1)

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http://dx.doi.org/10.1097/OLQ.0000000000000950DOI Listing
January 2019

Incidence, Clearance and Persistence of Anal HPV in Men who Have Sex with Men Living with HIV: Implications for HPV Vaccination.

Sex Transm Dis 2018 Nov 30. Epub 2018 Nov 30.

Central Clinical School, Monash University, Victoria 3800, Australia.

Background: Men who have sex with men (MSM) living with HIV have a high risk of anal cancer. We estimate the likely benefit of HPV vaccination amongst participants of the Anal Cancer Examination (ACE) study.

Methods: Anal swabs were collected for the detection and genotyping of anal HPV DNA by Linear Array (Roche Diagnostics) in this two-year multicentre prospective cohort. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000958DOI Listing
November 2018
2 Reads
2.842 Impact Factor

Treponema pallidum subsp. pallidum DNA and RNA in semen of a syphilis patient without genital or anal lesions. Possible implications for disease transmissibility.

Sex Transm Dis 2018 Dec 3. Epub 2018 Dec 3.

Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle (WA) USA.

Treponema pallidum subsp. pallidum DNA and RNA were detected in a semen specimen of a syphilis patient with no genital or anal sores and no clinically evident orchitis. No nucleic acids were found in a urine sample of the same patient collected immediately before the semen sample. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000956DOI Listing
December 2018
1 Read

Integrating HIV testing into syphilis partner services in Mississippi to improve HIV case finding.

Sex Transm Dis 2018 Dec 3. Epub 2018 Dec 3.

Department of Epidemiology, University of Washington, Seattle, WA, USA.

Background: Mississippi (MS) has the 10th highest rate of new HIV infections in the United States. The Mississippi State Department of Health (MSDH) integrated partner HIV testing into syphilis partner services (PS) in 2014, but the effectiveness of this as an HIV case-finding strategy has not been evaluated.

Methods: We identified all early syphilis (primary, secondary, and early latent) case records reported from 7/1/2014-12/31/2016, excluding case records for people concurrently newly diagnosed with HIV. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000951DOI Listing
December 2018
11 Reads