12,160 results match your criteria Serratia

Characterization of a new L-carnosine synthase mined from deep-sea sediment metagenome.

Microb Cell Fact 2022 Jun 27;21(1):129. Epub 2022 Jun 27.

College of Life Science, Hebei Normal University, Shijiazhuang, 050024, China.

L-Carnosine is a natural biologically active dipeptide with critical physiological functions, such as antioxidant, antiglycation, and cytoplasmic buffering properties. Direct enzymatic synthesis is a promising way for L-carnosine production. In this study, a new aminopeptidase (gene_236976) with synthetic activity toward L-carnosine was identified by a metagenome mining approach from deep-sea sediment and functionally expressed in Escherichia coli. Read More

View Article and Full-Text PDF

In vitro activity of aztreonam/avibactam against isolates of Enterobacterales collected globally from ATLAS in 2019.

J Glob Antimicrob Resist 2022 Jun 25. Epub 2022 Jun 25.

Pfizer Inc, Kirkland, Canada.

Objectives: Infections caused by drug-resistant Enterobacterales including those producing metallo-β-lactamases (MBLs) are particularly challenging due to limited therapeutic options. The drug combination aztreonam/avibactam (ATM-AVI) is under clinical development for treating serious infections caused by these strains. This study assessed the in vitro activity of ATM-AVI against Enterobacterales isolates collected globally in the ATLAS surveillance programme in 2019. Read More

View Article and Full-Text PDF

Draft Genome Sequence of Serratia marcescens SSA1, Isolated from Dioxin-Polluted Soil.

Microbiol Resour Announc 2022 Jun 27:e0023622. Epub 2022 Jun 27.

Department of Microbiology, Faculty of Science, University of Lagos, Lagos, Nigeria.

Serratia marcescens SSA1 was isolated from a dump site with a history of incineration. Its DNA of 5.05 Mbp has a GC content of 59. Read More

View Article and Full-Text PDF

Antimicrobial susceptibility testing profiles of ESBL-producing isolated from hospital and community adult patients in Blantyre, Malawi.

IJID Reg 2021 Dec 6;1:47-52. Epub 2021 Sep 6.

Department of Pathology, College of Medicine, Kamuzu University of Health Sciences, Private Bag 360, Blantyre, Malawi.

Objective: There is a paucity of data on antimicrobial resistance (AMR) in Malawi. Here we present a study of AMR of extended-spectrum β-lactamases-producing (ESBL-E) isolated from hospital and community settings in Blantyre, Malawi.

Design And Methods: A cross-sectional study was conducted between March and November 2020, involving 403 adult participants aged ≥18 years. Read More

View Article and Full-Text PDF
December 2021

The Response of the Rodent Gut Microbiome to Broad-Spectrum Antibiotics Is Different in Males and Females.

Front Microbiol 2022 9;13:897283. Epub 2022 Jun 9.

Medically Associated Science and Technology (MAST) Program, Cedars-Sinai, Los Angeles, CA, United States.

Gut microbiome composition is different in males and females, but sex is rarely considered when prescribing antibiotics, and sex-based differences in gut microbiome recovery following antibiotic treatment are poorly understood. Here, we compared the effects of broad-spectrum antibiotics on both the stool and small bowel microbiomes in male and female rats. Adult male and female Sprague Dawley rats were exposed to a multi-drug antibiotic cocktail for 8 days, or remained unexposed as controls. Read More

View Article and Full-Text PDF

Analysis of Microbiological and Clinical Characteristics of Bacterial Infection in Patients with Pulmonary Infection.

Taimei Duan

Comput Intell Neurosci 2022 16;2022:5607358. Epub 2022 Jun 16.

The First People's Hospital of Chongqing Liangjiang New Area, Chongqing 401121, China.

Objective: Using data investigation, the microbiology of bacterial infection in patients with pulmonary infection was discussed, and its clinical characteristics were analyzed.

Methods: The clinical data of 160 patients with pulmonary infection in our hospital from March 2019 to March 2021 were collected and analyzed. Blood samples were collected and cultured, and the pathogens were identified. Read More

View Article and Full-Text PDF

Remedial Aspect of Zinc Oxide Nanoparticles Against and .

Front Pharmacol 2022 7;13:891304. Epub 2022 Jun 7.

Department of Biomedical Science, Universiti Tunku Abdul Rahman (UTAR), Kampar, Malaysia.

Zinc oxide nanoparticles (ZnO NPs) have been widely used in biomedical applications due to their high biocompatibility and low toxicity to humans. The present work aimed to investigate the antibacterial effects of different concentrations of ZnO NPs on two opportunistic pathogens, and . The surface interaction between nanoparticles and bacterial cell wall, and the subsequent morphological alterations on the bacterial surface, were examined through Fourier transform infrared spectroscopy and scanning electron microscope. Read More

View Article and Full-Text PDF

Synthesis, Anticancer Potential and Comprehensive Toxicity Studies of Novel Brominated Derivatives of Bacterial Biopigment Prodigiosin from ATCC 27117.

Molecules 2022 Jun 9;27(12). Epub 2022 Jun 9.

Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, 11000 Belgrade, Serbia.

Prodigiosins (prodiginines) are a class of bacterial secondary metabolites with remarkable biological activities and color. In this study, optimized production, purification, and characterization of prodigiosin (PG) from easily accessible ATCC 27117 strain has been achieved to levels of 14 mg/L of culture within 24 h. Furthermore, environmentally friendly bromination of produced PG was used to afford both novel mono- and dibrominated derivatives of PG. Read More

View Article and Full-Text PDF

Role of Marine Bacterial Contaminants in Histamine Formation in Seafood Products: A Review.

Microorganisms 2022 Jun 11;10(6). Epub 2022 Jun 11.

Department of Plant Sciences, North Dakota State University, Fargo, ND 58102, USA.

Histamine is a toxic biogenic amine commonly found in seafood products or their derivatives. This metabolite is produced by histamine-producing bacteria (HPB) such as , , , , , , , , spp., , , , , , , , , , spp. Read More

View Article and Full-Text PDF

Assessing the Tsetse Fly Microbiome Composition and the Potential Association of Some Bacteria Taxa with Trypanosome Establishment.

Microorganisms 2022 May 31;10(6). Epub 2022 May 31.

Centre for Research in Infectious Diseases (CRID), Yaoundé P.O. Box 13591, Cameroon.

The tsetse flies, biological vectors of African trypanosomes, harbour a variety of bacteria involved in their vector competence that may help in developing novel vector control tools. This study provides an inventory of tsetse bacterial communities in Cameroon and explores their possible associations with trypanosome establishment in . High throughput sequencing of the V3-V4 hypervariable region of the bacterial 16S rRNA gene, with subsequent metagenomic, multivariate, and association analyses, were used to investigate the levels and patterns of microbial diversity in four tsetse species. Read More

View Article and Full-Text PDF

Bacterial Resistance to Antibiotics and Clonal Spread in COVID-19-Positive Patients on a Tertiary Hospital Intensive Care Unit, Czech Republic.

Antibiotics (Basel) 2022 Jun 8;11(6). Epub 2022 Jun 8.

Department of Microbiology, Faculty of Medicine and Dentistry, Palacky University Olomouc, Hnevotinska 3, 779 00 Olomouc, Czech Republic.

This observational retrospective study aimed to analyze whether/how the spectrum of bacterial pathogens and their resistance to antibiotics changed during the worst part of the COVID-19 pandemic (1 November 2020 to 30 April 2021) among intensive care patients in University Hospital Olomouc, Czech Republic, as compared with the pre-pandemic period (1 November 2018 to 30 April 2019). A total of 789 clinically important bacterial isolates from 189 patients were cultured during the pre-COVID-19 period. The most frequent etiologic agents causing nosocomial infections were strains of (17%), (11%), (10%), coagulase-negative staphylococci (9%), (8%), (6%), (5%), (5%) and (5%). Read More

View Article and Full-Text PDF

Effect of copper stress on Phaseolus coccineus in the presence of exogenous methyl jasmonate and/or Serratia plymuthica from the Spitsbergen soil.

J Hazard Mater 2022 08 26;436:129232. Epub 2022 May 26.

Department of Analytical Chemistry, Medical University of Lublin, Chodźki 4a, 20-093, Lublin, Poland. Electronic address:

Copper stress in the presence of exogenous methyl jasmonate and Serratia plymuthica in a complete trifactorial design with copper (0, 50 µM), methyl jasmonate (0, 1, 10 µM) and Serratia plymuthica (without and with inoculation) was studied on the physiological parameters of Phaseolus coccineus. Copper application reduced biomass and allantoin content, but increased chlorophyll and carotenoids contents as well as catalase and peroxidases activities. Jasmonate did not modify biomass and organic acids levels under copper treatment, but additional inoculation elevated biomass and content of tartrate, malate and succinate. Read More

View Article and Full-Text PDF

Prodigiosin: a promising biomolecule with many potential biomedical applications.

Bioengineered 2022 Jun;13(6):14227-14258

Laboratory of Urogenital Carcinogenesis and Immunotherapy, Biological Institute, Department of Structural and Functional Biology, University of Campinas, Campinas, Brazil.

Pigments are among the most fascinating molecules found in nature and used by human civilizations since the prehistoric ages. Although most of the bio-dyes reported in the literature were discovered around the eighties, the necessity to explore novel compounds for new biological applications has made them resurface as potential alternatives. Prodigiosin (PG) is an alkaloid red bio-dye produced by diverse microorganisms and composed of a linear tripyrrole chemical structure. Read More

View Article and Full-Text PDF

Distribution and Antimicrobial Resistance Profiles of Bacterial Aetiologies of Childhood Otitis Media in Accra, Ghana.

Microbiol Insights 2022 16;15:11786361221104446. Epub 2022 Jun 16.

Department of Medical Microbiology, University of Ghana Medical School, Accra, Ghana.

Background: Otitis media (OM), also known as middle ear infection, is a clinically significant childhood disease. In sub-Saharan Africa, there is a paucity of contemporary reports on it is bacterial aetiologies and antimicrobial resistance among them.

Aim: To investigate the OM bacterial aetiologies and their antimicrobial resistance patterns among children visiting the Ear, Nose, and Throat clinics of 3 healthcare facilities in Accra, Ghana - Princess Marie Louise Children's Hospital, 37 Military Hospital, and Mamprobi Hospital. Read More

View Article and Full-Text PDF

Bacterial diversity in Haemagogus leucocelaenus (Diptera: Culicidae) from Vale do Ribeira, São Paulo, Brazil.

BMC Microbiol 2022 Jun 22;22(1):161. Epub 2022 Jun 22.

Departamento de Epidemiologia, Faculdade de Saúde Pública, Universidade de São Paulo, Av. Dr. Arnaldo 715, São Paulo, SP, 01246-904, Brazil.

Introduction: Mosquitoes (Diptera: Culicidae) are vectors that transmit numerous pathogens to humans and other vertebrates. Haemagogus leucocelaenus is a mosquito associated with transmission of yellow fever virus. The insect gut harbors a variety of microorganisms that can live and multiply within it, thus contributing to digestion, nutrition, and development of its host. Read More

View Article and Full-Text PDF

Effect of volatile compounds produced by endophytic bacteria on virulence traits of grapevine crown gall pathogen, Agrobacterium tumefaciens.

Sci Rep 2022 Jun 22;12(1):10510. Epub 2022 Jun 22.

Department of Horticultural Science, Faculty of Agriculture, University of Kurdistan, Sanandaj, Iran.

The volatile organic compounds (VOCs) produced by endophytic bacteria have a significant role in the control of phytopathogens. In this research, the VOCs produced by endophytic bacteria including Serratia sp. Ba10, Pantoea sp. Read More

View Article and Full-Text PDF

Outbreak of IncX8 Plasmid-Mediated KPC-3-Producing Enterobacterales Infection, China.

Emerg Infect Dis 2022 07;28(7):1421-1430

Carbapenem-resistant Enterobacterales (CRE) infection is highly endemic in China; Klebsiella pneumoniae carbapenemase (KPC) 2-producing CRE is the most common, whereas KPC-3-producing CRE is rare. We report an outbreak of KPC-3-producing Enterobacterales infection in China. During August 2020-June 2021, 25 bla-positive Enterobacteriale isolates were detected from 24 patients in China. Read More

View Article and Full-Text PDF

In vitro susceptibilities of isolates of potentially naturally inducible chromosomal AmpC-producing metallo-β-lactamase-negative carbapenem-resistant Enterobacterales species to ceftazidime-avibactam: Data from the Antimicrobial Testing Leadership and Surveillance Programme, 2012-2019.

Int J Antimicrob Agents 2022 Jun 16:106617. Epub 2022 Jun 16.

Departments of Laboratory Medicine and Internal Medicine, China Medical University Hospital, School of Medicine, China Medical University, Taichung, Taiwan; School of Medicine, China Medical University, Taichung, Taiwan; Ph.D Program for Aging, School of Medicine, China Medical University, Taichung, Taiwan; Departments of Laboratory Medicine and Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address:

In total, 74,570 potentially naturally inducible chromosomal AmpC-producing (PNIC-AmpC) Enterobacterales isolates included in the Antimicrobial Testing Leadership and Surveillance Programme were obtained worldwide from 2012 to 2019 (22,503 from 2012 to 2014 and 52,067 from 2015 to 2019). One hundred seventeen and 711 isolates obtained in 2012-2014 and 2015-2019, respectively, were carbapenem-resistant Enterobacterales (PNIC-AmpC-CRE). The minimum inhibitory concentrations of ceftazidime-avibactam for these isolates against were determined using the broth microdilution method. Read More

View Article and Full-Text PDF

Interactions between intestinal morphology, digestion, inflammatory responses, and gut microbiota of juvenile channel catfish elicited by dietary enzymatic rice protein.

Fish Shellfish Immunol 2022 Jun 15;127:155-165. Epub 2022 Jun 15.

Hunan Engineering Technology Research Center of Featured Aquatic Resources Utilization, Hunan Agricultural University, Changsha, Hunan, 410128, China; College of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan, 410128, China. Electronic address:

The reduction of fishmeal in aquafeeds has been the concern of researchers. Replacing fishmeal with plant proteins affects intestinal function and inflammation, but the interaction between the intestinal responses and gut microbiota remains unclear. In this study, juvenile channel catfish (Ictalurus punctatus) was fed with four diets in which enzymatic rice protein (RP) replaced fishmeal at levels of 0 (FM), 2. Read More

View Article and Full-Text PDF

Insecticidal Serralysin of Is Detoxified in M3 Midgut Region of .

Front Microbiol 2022 31;13:913113. Epub 2022 May 31.

Metabolomics Research Center for Functional Materials, Kyungsung University, Busan, South Korea.

insect indiscriminately acquires not only the symbiotic bacterium , but also entomopathogens that are abundant in the soil feeding. However, it is unclear how the host insect survives oral infections of entomopathogens. A previous study suggested that serralysin, a potent virulence factor produced by , suppresses cellular immunity by degrading adhesion molecules, thereby contributing to bacterial pathogenesis. Read More

View Article and Full-Text PDF

Characteristics of Isolated from Intestinal Microbiota Children of 0-5 Years Old in the Commune of Abomey-Calavi.

J Pathog 2022 6;2022:6253894. Epub 2022 Jun 6.

Laboratory of Biology and Molecular Typing in Microbiology, Department of Biochemistry and Cellular Biology, Faculty of Sciences and Techniques, University of Abomey-Calavi, 05 BP 1604 Cotonou, Godomey, Benin.

is a commensal bacterium and one of the first bacteria to colonize the digestive tract of newborns after birth. It is characterized by great versatility and metabolic flexibility that allows its survival in different niches. The present study aims at analyzing the diversity of strains isolated from the intestinal microbiota of children aged from 0 to 5 years in the commune of Abomey-Calavi in Benin. Read More

View Article and Full-Text PDF

Dysbiosis and Restoration Dynamics of the Gut Microbiome Following Therapeutic Exposure to Florfenicol in Snubnose Pompano () to Aid in Sustainable Aquaculture Production Strategies.

Front Microbiol 2022 30;13:881275. Epub 2022 May 30.

Marine Biotechnology Division, Indian Council of Agricultural Research (ICAR)-Central Marine Fisheries Research Institute, Kochi, India.

Information on unintended effects of therapeutic exposure of antibiotics on the fish gut microbiome is a vital prerequisite for ensuring fish and environmental health during sustainable aquaculture production strategies. The present study forms the first report on the impact of florfenicol (FFC), a recommended antibiotic for aquaculture, on the gut microbiome of snubnose pompano (), a high-value marine aquaculture candidate. Both culture-dependent and independent techniques were applied to identify the possible dysbiosis and restoration dynamics, pointing out the probable risks to the host and environment health. Read More

View Article and Full-Text PDF

Cd exposure-triggered susceptibility to Bacillus thuringiensis in Lymantria dispar involves in gut microbiota dysbiosis and hemolymph metabolic disorder.

Ecotoxicol Environ Saf 2022 Jun 11;241:113763. Epub 2022 Jun 11.

School of Forestry, Northeast Forestry University, Harbin 150040, PR China; Key Laboratory of Sustainable Forest Ecosystem Management-Ministry of Education, Northeast Forestry University, Harbin 150040, PR China. Electronic address:

The immunotoxicity induced by heavy metals on herbivorous insects reflect the alterations of the susceptibility to entomopathogenic agents in herbivorous insects exposed to heavy metal. In the present study, the susceptibility of gypsy moth larvae to Bacillus thuringiensis under Cd treatment at low and high dosages was investigated, and the gut microbiome-hemolymph metabolome responses that affected larval disease susceptibility caused by Cd exposure were examined. Our results showed that mortality of gypsy moth larvae caused by B. Read More

View Article and Full-Text PDF

Chronic Granulomatous Disease: an Updated Experience, with Emphasis on Newly Recognized Features.

J Clin Immunol 2022 Jun 13. Epub 2022 Jun 13.

Division of Infectious Diseases, Ann & Robert H Lurie Children's Hospital of Chicago, 225 E Chicago Ave., Box 20, Chicago, IL, 60611, USA.

Purpose: Chronic granulomatous disease (CGD) is an uncommon, inborn error of immunity. We updated our large, single-center US experience with CGD and describe some newly recognized features.

Methods: We retrospectively reviewed 26 patients seen from November 2013 to December 2019. Read More

View Article and Full-Text PDF

Role of Essential Oil in Agricultural Products Safety: Antioxidant and Antimicrobial Applications.

Plants (Basel) 2022 Jun 3;11(11). Epub 2022 Jun 3.

Institute of Horticulture, Faculty of Horticulture and Landscape Engineering, Slovak University of Agriculture, Tr. A. Hlinku 2, 94976 Nitra, Slovakia.

The essential oil from (LCEO) has good antioxidant, antimicrobial, anti-insect properties, which gives it the potential for use as a natural additive to food resources and food products in order to prevent spoilage and extend shelf life. In this study the biological activity related to food preservation was observed. The main volatile organic compounds were geranial (39. Read More

View Article and Full-Text PDF

Heat Stress Affects Jejunal Immunity of Yellow-Feathered Broilers and Is Potentially Mediated by the Microbiome.

Front Physiol 2022 23;13:913696. Epub 2022 May 23.

Department of Human Nutrition, Food and Animal Sciences, College of Tropical Agriculture and Human Resources, University of Hawaii at Manoa, Honolulu, HI, United States.

In the perspective of the global climate change leading to increasing temperature, heat stress (HS) has become a severe issue in broiler production, including the indigenous yellow-feathered broilers. The present study aimed to investigate the effects of HS on jejunal immune response, microbiota structure and their correlation in yellow-feathered broilers. A total of forty female broilers (56-days-old) were randomly and equally divided into normal treatment group (NT group, 21. Read More

View Article and Full-Text PDF

Invasion History of the Pinewood Nematode Influences the Abundance of sp. in Pupal Chambers and Tracheae of Insect-Vector .

Front Plant Sci 2022 20;13:856841. Epub 2022 May 20.

State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.

Pine wilt disease (PWD) has caused extensive mortality in pine forests worldwide. This disease is a result of a multi-species interaction among an invasive pinewood nematode (PWN) , its vector sp. beetle, and the host pine tree ( sp. Read More

View Article and Full-Text PDF

Long-term monitoring of antibody titers against microorganisms in human intravenous immunoglobulin lots derived from healthy donors in Japan manufactured during 1998-2018.

Transfusion 2022 Jun 4. Epub 2022 Jun 4.

Biomet K.K, Tokyo, Japan.

Background: Studies evaluating long-term trends of intravenous immunoglobulin (IVIG) titers against microorganisms such as bacteria and fungi have not been conducted. We herein evaluated long-term trends of titers of IVIG lots manufactured from 1998 to 2018, derived from donors in Japan, against microorganisms affecting patients with primary or secondary immunodeficiency diseases.

Study Design And Methods: Titers against four strains of Pseudomonas aeruginosa, three strains of Staphylococcus aureus, four strains of Haemophilus influenzae, two strains of Klebsiella pneumoniae, one strain of Streptococcus pneumoniae, Enterococcus faecium, Bordetella pertussis, Serratia marcescens, and Candida albicans, were tested immediately after lot release in a commercial clinical testing facility in 1998. Read More

View Article and Full-Text PDF

Recent emergence of.

Eur J Dermatol 2022 Jan;32(1):94-98

Background Skin is one of the organs associated with Serratia marcescens infection. The associated morbidity can be significant, however, information is lacking. Objectives To identify characteristics of cases with cutaneous infection of Serratia marcescens. Read More

View Article and Full-Text PDF
January 2022

Isolation of bacterial strains from compost teas and screening of their PGPR properties on potato plants.

Environ Sci Pollut Res Int 2022 Jun 2. Epub 2022 Jun 2.

Laboratory of Plant Improvement and Agro-Resources Valorization, National School of Engineers of Sfax, road of Soukra Km 4, B.P 1173, 3038, Sfax, Tunisia.

The beneficial effect of compost and compost tea on plant growth and protection is mainly associated with the microbial diversity and the presence of bacteria with plant growth-promoting effect. PGPR are considered as eco-friendly bio-fertilizers that may reduce the use of chemical pesticides and fertilizers. Three composts (AT, A10, and A30) were previously prepared from industrial wastes (olive mill wastewater, olive pomace, coffee ground, and phosphogypsum). Read More

View Article and Full-Text PDF