10,661 results match your criteria Serratia


First reported nosocomial outbreak of harboring and in a neonatal intensive care unit in Cairo, Egypt.

Infect Drug Resist 2018 8;11:2211-2217. Epub 2018 Nov 8.

Department of Microbiology, Faculty of Dentistry and Oral Medicine, Future University, Cairo, Egypt.

Introduction: is a significant hospital-acquired pathogen, and many outbreaks of infection have been reported in neonates. We report a sudden breakout of harboring the and metallo-β-lactamase (MBL) genes that occurred from March to August 2015 in the neonatal intensive care unit of Cairo University Hospital, Cairo, Egypt.

Methods: During the study period, 40 nonduplicate clinical isolates of were collected from blood culture samples. Read More

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November 2018

Triatomines: Trypanosomatids, Bacteria, and Viruses Potential Vectors?

Front Cell Infect Microbiol 2018 16;8:405. Epub 2018 Nov 16.

Laboratório de Interação Patógeno-Hospedeiro, Instituto de Ciências Biológicas, Departamento de Biologia Celular, Universidade de Brasília, Brasília, Brazil.

Triatominae bugs are the vectors of Chagas disease, a major concern to public health especially in Latin America, where vector-borne Chagas disease has undergone resurgence due mainly to diminished triatomine control in many endemic municipalities. Although the majority of Triatominae species occurs in the Americas, species belonging to the genus occur in India, and species belonging to the complex have been also identified in Africa, the Middle East, South-East Asia, and in the Western Pacific. Not all of Triatominae species have been found to be infected with , but the possibility of establishing vector transmission to areas where Chagas disease was previously non-endemic has increased with global population mobility. Read More

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November 2018
1 Read

[Obstructive tracheobronchitis due to Aspergillus fumigatus in an immunocompetent patient].

Rev Iberoam Micol 2018 Nov 29. Epub 2018 Nov 29.

Servicio de Microbiología, Hospital Universitario Puerta del Mar, Cádiz, España; Instituto de Investigación Biomédica de Cádiz (INiBICA), Cádiz, España.

Background: Aspergillus tracheobronchitis (ATB) is an uncommon type of invasive pulmonary aspergillosis in which fungal involvement is limited to the tracheobronchial tree. While the more severe forms, such as pseudomembranous and ulcerative ATB, occur almost exclusively in immunocompromised patients, the milder obstructive form may occur in patients without immune deficiency.

Case Report: The case of a 32 year-old man with no previous history of illness, who was evaluated for recurrent right lower lobe pneumonia, is presented. Read More

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November 2018

An Outbreak of in a Moroccan Neonatal Intensive Care Unit.

Adv Med 2018 1;2018:4867134. Epub 2018 Nov 1.

Neonatal Intensive Care Unit, Mother-Child Center, Mohammed VI University Medical Hospital of Marrakesh, Morocco.

() is an microorganism that is widespread in the environment, which may be the source of nosocomial infections, rare in the newborn but severe, and often in the form of outbreaks. The aim of our study is to report our experience, during an outbreak of , to show the severity of this germ, with review of the literature. Our study was retrospective, including 8 newborns with nosocomial infection, collected in the neonatal intensive care unit of Mohammed VI University Medical Hospital, during the epidemic period, over a period of 2 months (July and August 2016). Read More

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November 2018
1 Read

Kinetic insights into the role of the reductant in HO-driven degradation of chitin by a bacterial lytic polysaccharide monooxygenase.

J Biol Chem 2018 Dec 4. Epub 2018 Dec 4.

University of Tartu, Estonia.

Lytic polysaccharide monooxygenases (LPMOs) are mono-copper enzymes that catalyze oxidative cleavage of glycosidic bonds in polysaccharides in the presence of an external electron donor (reductant). In the classical O-driven monooxygenase reaction, the reductant is needed in stoichiometric amounts. In a recently discovered, more efficient HO-driven reaction, the reductant would be needed only for the initial reduction (priming) of the LPMO to its catalytically active Cu(I) form. Read More

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December 2018

An auxin controls bacterial antibiotics production.

Nucleic Acids Res 2018 Nov;46(21):11229-11238

Department of Environmental Protection, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas, 18008 Granada, Spain.

The majority of clinically used antibiotics originate from bacteria. As the need for new antibiotics grows, large-scale genome sequencing and mining approaches are being used to identify novel antibiotics. However, this task is hampered by the fact that many antibiotic biosynthetic clusters are not expressed under laboratory conditions. Read More

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November 2018

Capture, Concentration and Detection of Salmonella in Foods Using Magnetic Ionic Liquids and Recombinase Polymerase Amplification.

Anal Chem 2018 Nov 30. Epub 2018 Nov 30.

We have previously investigated the extraction and concentration of bacteria from model systems using magnetic ionic liquid (MIL) solvents, while retaining their viability. Here, we combine MIL-based sample preparation with isothermal amplification and detection of Salmonella-specific DNA using Recombinase Polymerase Amplification (RPA). After initial developmental work with Serratia marcescens in water, Salmonella Typhimurium ATCC 14028 was inoculated in water, 2% milk, almond milk or liquid egg samples and extracted using one of two MILs, including: trihexyl(tetradecyl)phosphonium cobalt(II) hexafluoroacetylacetonate ([P][Co(hfacac)]) and trihexyl(tetradecyl)phosphonium nickel(II) hexafluoroacetylacetonate ([P][Ni(hfacac)]). Read More

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November 2018
4 Reads

Bacterial and Parasitic Assessment from Fingernails in Debre Markos, Northwest Ethiopia.

Can J Infect Dis Med Microbiol 2018 18;2018:6532014. Epub 2018 Oct 18.

Department of Medical Laboratory Science, College of Medical and Health Sciences, Debre Markos University, Debre Markos, Ethiopia.

Background: Food handlers with untrimmed finger nails could contribute or serve as a vehicle for the transmission of food poisoning pathogens.

Objectives: This study was conducted to determine the prevalence of bacteria and intestinal parasites among food handlers and antibiotic susceptibility profile of the isolated bacteria in Debre Markos University, Ethiopia.

Materials And Methods: This laboratory-based cross-sectional study involved 220 food handlers working in food service establishments in Debre Markos University between 1st January 2015 to 31th June 2016. Read More

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October 2018
4 Reads

Biochemical identification techniques and antibiotic susceptibility profile of lipolytic ambiental bacteria from effluents.

Braz J Biol 2018 Nov 23. Epub 2018 Nov 23.

Laboratório de Micologia e Bioprospecção, Departamento de Microbiologia e Parasitologia, Instituto de Biologia, Universidade Federal de Pelotas - UFPel, Av. Eliseu Maciel, IB Prédio 18, Sala 03, CEP 96160-000, Capão do Leão, RS, Brasil.

Different methodologies have been developed throughout the years to identify environmental microorganisms to improve bioremediation techniques, determine susceptibility profiles of bacteria in contaminated environments, and reduce the impact of microorganisms in ecosystems. Two methods of bacterial biochemical identification are compared and the susceptibility profile of bacteria, isolated from residential and industrial wastewater, is determined. Twenty-four bacteria were retrieved from the bacteria bank of the Environmental Microbiology Laboratory at the Institute of Biology (IB) of the Universidade Federal de Pelotas, Pelotas, Brazil. Read More

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November 2018

Characterization of Gene Families Encoding Beta-Lactamases of Gram-Negative Rods Isolated from Ready-to-Eat Vegetables in Mexico City.

High Throughput 2018 Nov 23;7(4). Epub 2018 Nov 23.

Laboratorio de Medicina Genómica, Hospital Regional "Primero de Octubre", ISSSTE, Av. Instituto Politécnico Nacional 1669, Lindavista, Gustavo A. Madero, Ciudad de Mexico 07300, Mexico.

Beta-lactam resistant bacteria, which are commonly resident in tertiary hospitals, have emerged as a worldwide health problem because of ready-to-eat vegetable intake. We aimed to characterize the genes that provide resistance to beta-lactam antibiotics in Enterobacteriaceae, isolated from five commercial salad brands for human consumption in Mexico City. In total, twenty-five samples were collected, grown in blood agar plates, and the bacteria were biochemistry identified and antimicrobial susceptibility testing was done. Read More

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November 2018

Molecular cloning and characterization of a methyl parathion hydrolase from an organophosphorus-degrading bacterium, Serratia marcescens MEW06.

FEMS Microbiol Lett 2018 Dec;365(24)

State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-resources, School of Life Sciences, Hubei University, Wuhan, 430062, PR China.

An organophosphorus-degrading bacterium MEW06, which exhibited excellent biodegradation capabilities towards 50 mg/L of methyl parathion (MP), paraoxon and dimethoate, was isolated from Sand Lake (Wuhan, China) and identified as Serratia marcescens subsp. marcescens based on physiological-biochemical characteristics and a 16S rDNA sequence-based phylogenetic tree. MEW06 genome contains a 31. Read More

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December 2018

Effect of gastric fluid aspiration on the lung microbiota of laboratory rats.

Exp Lung Res 2018 Nov 22:1-10. Epub 2018 Nov 22.

a Department of Surgery , Duke University Medical Center , Durham , North Carolina , USA.

Aim Of The Study: The pulmonary microbiota is important for both normal homeostasis and the progression of disease, and may be affected by aspiration of gastric fluid. The aim of this study was to investigate changes in the lung microbiota induced by aspiration of gastric fluid in a laboratory rat model.

Material And Methods: Using the intratracheal application method, male rats received aspiration with 0. Read More

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November 2018
3 Reads

Low Temperature Synthesis of Superparamagnetic Iron Oxide (FeO) Nanoparticles and Their ROS Mediated Inhibition of Biofilm Formed by Food-Associated Bacteria.

Front Microbiol 2018 5;9:2567. Epub 2018 Nov 5.

Department of Agricultural Microbiology, Aligarh Muslim University, Aligarh, India.

In the present study, a facile environmentally friendly approach was described to prepare monodisperse iron oxide (FeO) nanoparticles (IONPs) by low temperature solution route. The synthesized nanoparticles were characterized using x-ray diffraction spectroscopy (XRD), Raman spectroscopy, field emission scanning electron microscopy (FESEM) measurements, Fourier-Transform Infrared Spectroscopy (FTIR), and Thermogravimetric analysis (TGA) analyses. XRD patterns revealed high crystalline quality of the nanoparticles. Read More

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November 2018
4 Reads

Delivery of a Genetically Marked Serratia AS1 to Medically Important Arthropods for Use in RNAi and Paratransgenic Control Strategies.

Microb Ecol 2018 Nov 20. Epub 2018 Nov 20.

Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, P.O.Box: 14155-6446, Tehran, Iran.

Understanding how arthropod vectors acquire their bacteria is essential for implementation of paratransgenic and RNAi strategies using genetically modified bacteria to control vector-borne diseases. In this study, a genetically marked Serratia AS1 strain expressing the mCherry fluorescent protein (mCherry-Serratia) was used to test various acquisition routes in six arthropod vectors including Anopheles stephensi, Culex pipiens, Cx. quinquefaciatus, Cx. Read More

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November 2018
6 Reads

[Chronic granulomatous disease: multiple infections as clinical presentation. Pediatric case report].

Arch Argent Pediatr 2018 Dec;116(6):e744-e748

Servicio de Infectología, Hospital de Niños Sor María Ludovica.

Chronic granulomatous disease is an uncommon primary immunodeficiency due to a defect of the killing activity of phagocytes, caused by mutations in any of the genes encoding subunits of the superoxide-generating phagocyte NADPH oxidase system. The incidence is 1 in 250 000 live births. It can occur from infancy to adulthood, usually in children under 2 years. Read More

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December 2018
1 Read

Biosurfactants produced by Serratia species: Classification, biosynthesis, production and application.

Appl Microbiol Biotechnol 2018 Nov 19. Epub 2018 Nov 19.

Department of Microbiology, Faculty of Science, Stellenbosch University, Private Bag X1, Stellenbosch, 7602, South Africa.

Biosurfactants are surface-active molecules that are synthesised non-ribosomally by a wide range of microorganisms including bacteria, yeast and filamentous fungi. The bacterial genus Serratia is gaining international interest, as biosurfactants produced by this genus have emerged as a promising source of antimicrobial, antifouling and antitumour compounds that possess emulsification and surface activity. Various species of Serratia have been identified as biosurfactant producers, including Serratia marcescens, Serratia rubidaea and Serratia surfactantfaciens. Read More

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November 2018
11 Reads

Isolation and characterization of endophytes from nodules of Mimosa pudica with biotechnological potential.

Microbiol Res 2019 Jan 6;218:76-86. Epub 2018 Oct 6.

Centro de Investigación en Biotecnología, Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos, Mexico. Electronic address:

Legumes establish symbiotic relationships with different microorganisms, which could function as plant growth promotion microorganisms (PGPM). The finding of new PGPM strains is important to increase plant production avoiding or diminishing the use of industrial fertilizers. Thus, in this work we evaluated the plant growth promotion traits of ten strains isolated from Mimosa pudica root nodules. Read More

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January 2019
5 Reads

Screening of bacterial isolates related to olive orchard pests in Tunisia using 16S ribosomal RNA and evaluation of their biotechnological potential.

J Appl Microbiol 2018 Nov 19. Epub 2018 Nov 19.

Institute for Microbiology and Biochemistry, Geisenheim University, Germany.

Aim: This study investigated the bacterial diversity of dead insects collected from olive tree orchards widely cultivated in Tunisia. We aimed to explore metabolic diversity, screen enzymatic activities for biotechnological applications and carry out preliminary bioassays for bio-insecticide development.

Methods And Results: A total of 50 bacteria strains were randomly isolated from 4 different biotopes situated in Sfax (Tunisia). Read More

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November 2018
2 Reads

Pseudohemoptysis in an elderly due to pneumonitis.

Med J Armed Forces India 2018 Oct 5;74(4):383-385. Epub 2017 Oct 5.

Consultant and Head, Department of Pathology, Command Hospital (Southern Command), Pune 411040, India.

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October 2018
1 Read

The effects of bacterial endotoxin (LPS) on cardiac function in a medicinal blow fly (Phaenicia sericata) and a fruit fly (Drosophila melanogaster).

Comp Biochem Physiol C Toxicol Pharmacol 2018 Nov 15;217:15-24. Epub 2018 Nov 15.

Department of Biology, Center for Muscle Biology, University of Kentucky, Lexington, KY 40506-0225, USA. Electronic address:

The bacterial endotoxins, lipopolysaccharides (LPS), are known to have direct effects on mammalian heart cells; thus, LPS is likely to have some effects in other cardiac models. Drosophila melanogaster was used since it serves as a model for cardiac physiology. Larvae of blow flies (Phaenicia sericata) commonly used as therapy for debriding dead tissue, are exposed to high levels of bacterial endotoxins, but their mechanisms of LPS resistance are not entirely understood. Read More

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November 2018
3 Reads

Interspecific formation of the antimicrobial volatile schleiferon.

Sci Rep 2018 Nov 15;8(1):16852. Epub 2018 Nov 15.

Institute of Biological Science, University of Rostock, Albert-Einstein-Straße 3, 18059, Rostock, Germany.

Microorganisms release a plethora of volatile secondary metabolites. Up to now, it has been widely accepted that these volatile organic compounds are produced and emitted as a final product by a single organism e.g. Read More

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November 2018

Production, purification and biochemical characterization of a thermoactive, alkaline lipase from a newly isolated Serratia sp. W3 Tunisian strain.

Int J Biol Macromol 2018 Nov 12;123:792-800. Epub 2018 Nov 12.

Laboratory of Biochemistry and Enzymatic Engineering of Lipases, National School of Engineers of Sfax, University of Sfax, PB 1173, Km 4 Road Soukra, Sfax, Tunisia.

A newly isolated Serratia sp. W3 strain was shown to secrete a non-induced lipase in the culture medium. Lipolytic activity was optimized using the response surface methodology (RSM) and the extracellular lipase from Serratia sp. Read More

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November 2018
4 Reads
2.860 Impact Factor

A global priority list of the TOp TEn resistant Microorganisms (TOTEM) study at intensive care: a prioritization exercise based on multi-criteria decision analysis.

Eur J Clin Microbiol Infect Dis 2018 Nov 13. Epub 2018 Nov 13.

Department of emergency medicine, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.

The World Health Organization (WHO) proposed a global priority pathogen list (PPL) of multidrug-resistant (MDR) bacteria. Our current objective was to provide global expert ranking of the most serious MDR bacteria present at intensive care units (ICU) that have become a threat in clinical practice. A proposal addressing a PPL for ICU, arising from the WHO Global PPL, was developed. Read More

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November 2018
6 Reads

Limited added value of fungal ITS amplicon sequencing in the study of bovine abortion.

Heliyon 2018 Nov 5;4(11):e00915. Epub 2018 Nov 5.

Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Laenggassstrasse 122, CH-3012 Bern, Switzerland.

Bovine mycotic abortion is sporadic and caused by different ubiquitous and opportunistic fungi. Recently, a broad spectrum of bacterial opportunists involved in bovine abortion was revealed by 16S rRNA gene amplicon sequencing. We hypothesized that fungal organisms potentially involved in bovine abortion also might remain undetected by conventional culture. Read More

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November 2018
4 Reads

Molecular and Microbiological Insights on the Enrichment Procedures for the Isolation of Petroleum Degrading Bacteria and Fungi.

Front Microbiol 2018 30;9:2543. Epub 2018 Oct 30.

Department for Sustainable Food Processes, Università Cattolica del Sacro Cuore, Piacenza, Italy.

Autochthonous bioaugmentation, by exploiting the indigenous microorganisms of the contaminated environment to be treated, can represent a successful bioremediation strategy. In this perspective, we have assessed by molecular methods the evolution of bacterial and fungal communities during the selective enrichment on different pollutants of a soil strongly polluted by mixtures of aliphatic and polycyclic hydrocarbons. Three consecutive enrichments were carried out on soil samples from different soil depths (0-1, 1-2, 2-3 m), and analyzed at each step by means of high-throughput sequencing of bacterial and fungal amplicons biomarkers. Read More

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October 2018
6 Reads

Upregulation of Helicoverpa armigera core RNAi genes by bacterial infections and its effect on the insect-bacteria interaction.

Insect Mol Biol 2018 Nov 13. Epub 2018 Nov 13.

Department of Entomology, Faculty of Agriculture Tarbiat Modares University, Tehran, Iran.

RNA interference (RNAi) is an extremely conserved defense mechanism. The antiviral role of the RNAi pathway in insects is well documented; however, the relevance of this pathway in other aspects of insect immunity is largely unknown. In this study, we questioned whether RNAi has any function during insect-bacteria interactions. Read More

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November 2018

Quorum quelling efficacy of marine cyclic dipeptide -cyclo(L-leucyl-L-prolyl) against the uropathogen Serratia marcescens.

Food Chem Toxicol 2018 Nov 9;123:326-336. Epub 2018 Nov 9.

Department of Biotechnology, Alagappa University, Science Campus, Karaikudi, 630003, Tamil Nadu, India.

In the current study, the anti-quorum sensing (QS) efficacy of cyclic dipeptide -cyclo(L-leucyl-L-prolyl) (CLP) of marine origin was explored against Serratia marcescens. Minimal -inhibitory (MIC) and -bactericidal concentrations (MBC) of CLP against both reference as well as a clinical isolate of S. marcescens was identified to be 200 and 400 µg/mL, respectively. Read More

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November 2018
2 Reads

Bacteriostatic and Bactericidal Activity of Deer Musk on Multidrug Resistance Bacteria.

Pak J Biol Sci 2018 Jan;21(7):331-339

Background And Objective: Infecting agents (e.g., bacteria, fungi, virus and parasite) have comprised high levels of multidrug resistance (MDR) with increased morbidity and mortality; so the main aim of this study was to investigate and demonstrate the antimicrobial activity of deer musk on multidrug-resistance bacteria and to proof that musk had a bacteriostatic and bactericidal effects against MDR bacteria. Read More

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January 2018
2 Reads

Influence of Feeding Type and Infection on the Gut Microbiota of Workers.

mSystems 2018 Nov-Dec;3(6). Epub 2018 Nov 6.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

The gut microbiota plays an essential role in the health of bees. To elucidate the effect of feed and Nosema ceranae infection on the gut microbiota of honey bee (Apis cerana), we used 16S rRNA sequencing to survey the gut microbiota of honey bee workers fed with sugar water or beebread and inoculated with or without N. ceranae. Read More

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November 2018
6 Reads

Seed Extract of and Its Constituent Bakuchiol Impairs AHL-Based Quorum Sensing and Biofilm Formation in Food- and Human-Related Pathogens.

Front Cell Infect Microbiol 2018 25;8:351. Epub 2018 Oct 25.

Department of Chemistry, Rhodes University, Grahamstown, South Africa.

The emergence of multi-drug resistance in pathogenic bacteria in clinical settings as well as food-borne infections has become a serious health concern. The problem of drug resistance necessitates the need for alternative novel therapeutic strategies to combat this menace. One such approach is targeting the quorum-sensing (QS) controlled virulence and biofilm formation. Read More

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October 2018
6 Reads
2.620 Impact Factor

High rate of colistin and fosfomycin resistance among carbapenemase-producing Enterobacteriaceae in Turkey.

Acta Microbiol Immunol Hung 2018 Nov 7:1-10. Epub 2018 Nov 7.

3 Department of Clinical Microbiology, Ankara Training and Research Hospital , Ankara, Turkey.

When the problem with carbapenem-resistant Enterobacteriaceae (CRE) increases, the older antimicrobial agents such as colistin and fosfomycin are used for the treatment of these infections. In this study, the broth microdilution method for colistin and the agar dilution method for fosfomycin were used for a total of 147 multidrug-resistant (MDR) or extensively drug-resistant (XDR) strains of CRE. The study included Klebsiella pneumoniae (91. Read More

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November 2018
6 Reads

Construction and co-cultivation of two mutant strains harboring key precursor genes to produce prodigiosin.

J Biosci Bioeng 2018 Dec 29;126(6):783-789. Epub 2018 Jun 29.

Graduate School of Biotechnology and Bioengineering, Yuan Ze University, No. 135, Yuan-Tung Road, Chung-Li Dist., Taoyuan City 32003, Taiwan, ROC. Electronic address:

The biosynthesis of prodigiosin (PG) from Serratia marcescens involves the coupling of a bipyrrole, 4-methoxy-2,2'-bipyrrole-5-carboxaldehyde (MBC), with a monopyrrole, 2-methyl-3-n-amyl-pyrrole (MAP), and formation of a linear tripyrrole (PG). We constructed mutant strains in which either the MBC biosynthesis by S. marcescens BMJ816 or the MAP biosynthesis by S. Read More

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December 2018

Biological Potential and Mechanism of Prodigiosin from Subsp. in Human Choriocarcinoma and Prostate Cancer Cell Lines.

Int J Mol Sci 2018 Nov 4;19(11). Epub 2018 Nov 4.

Engineering Research Center of Agricultural Microbiology Technology, Ministry of Education, Heilongjiang University, Harbin 150080, China.

Tripyrrole molecules have received renewed attention due to reports of numerous biological activities, including antifungal, antibacterial, antiprotozoal, antimalarial, immunosuppressive, and anticancer activities. In a screen of bacterial strains with known toxicities to termites, a red pigment-producing strain, HDZK-BYSB107, was isolated from , which grows in Oregon, USA. Strain HDZK-BYSB107 was identified as subsp. Read More

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November 2018
4 Reads
2.860 Impact Factor

Structural characterization and biological evaluation of Staphylosan (dimannooleate), a new glycolipid surfactant produced by a marine Staphylococcus saprophyticus SBPS-15.

Enzyme Microb Technol 2019 Jan 21;120:1-7. Epub 2018 Sep 21.

Faculty of Marine Sciences, Annamalai University, Porto Novo, Tamil Nadu 608502, India.

Marine microbes have gained significant attention as potential biofactories for broad spectrum bioactive compounds. In the recent years, bioactive biosurfactants have warranted renewed interest from both environmental and clinical sectors as anti-biofilm agents due to their excellent properties of dispersing microbial biofilms. The present study explores a new glycolipid biosurfactant produced by a marine Staphylococcus saprophyticus exhibiting interesting biological activities. Read More

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January 2019
4 Reads

Molecular dynamics simulation analysis of conessine against multi drug resistant Serratia marcescens.

Infect Genet Evol 2018 Nov 2;67:101-111. Epub 2018 Nov 2.

Department of Biological Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, Allahabad 211007, U.P., India. Electronic address:

Ornithine decarboxylase (ODC) is an immediate precursor of polyamine biosynthesis in Serratia marcescens and a potential target for inhibition of its growth. We predicted the 3D structural conformation of ODC enzyme and validated it using MDS in our previous study. In this current study, the potential inhibitors of ODC were obtained by virtual screening of potential inhibitors from ZINC database and studied in depth for their different binding pose. Read More

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November 2018
5 Reads

Serratia marcescens outbreak in a neonatology unit of a Spanish tertiary hospital: Risk factors and control measures.

Am J Infect Control 2018 Nov 1. Epub 2018 Nov 1.

Department of Preventive Medicine, La Paz University Hospital, Madrid, Spain.

Background: We describe the investigation undertaken and the measures adopted to control a Serratia marcescens outbreak in the neonatology unit of La Paz University Hospital in Madrid, Spain.

Methods: Weekly rectal and pharyngeal screenings for S marcescens were performed in the neonates starting after detection of the outbreak. Environmental samples and samples from health care workers (HCWs) were obtained for microbiological analysis. Read More

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November 2018
3 Reads

N-substituted piperazinyl sarafloxacin derivatives: synthesis and in vitro antibacterial evaluation.

Daru 2018 Dec 3;26(2):199-207. Epub 2018 Nov 3.

Drug Design and Development Research Center, The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran, Iran.

Background: Fluoroquinolones (FQs) are compounds of major interest with broad antimicrobial activities against community and hospital-acquired infections such as respiratory tract infections (nosocomial pneumonia, chronic bronchitis and tuberculosis), skin and soft tissue infections, bone and joint infections, intra-abdominal infections and sexually transmitted diseases. This broad range of activities along with favorable pharmacokinetic and low toxicity introduced this class of compounds as important antimicrobial chemotherapy agents. The rapid increase in prevalence of FQs resistant microbes in environment motivated medicinal chemists to discover new quinolone-based compounds with potent activities against Gram-positive bacteria. Read More

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December 2018
4 Reads

Effect of Serratia AS1 (Enterobacteriaceae: Enterobacteriales) on the Fitness of Culex pipiens (Diptera: Culicidae) for Paratransgenic and RNAi Approaches.

J Med Entomol 2018 Nov 2. Epub 2018 Nov 2.

Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

The mosquito Culex pipiens is the primary vector of Rift Valley fever, West Nile, encephalitis, and Zika viruses, and periodic lymphatic filariasis. Developing insecticide resistance in mosquitoes demands the development of new approaches to fight these diseases. Paratransgenesis and RNAi approaches by using engineered bacteria have been shown to reduce mosquito vector competence. Read More

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November 2018
3 Reads

Bacterial biophotons as non-local information carriers: Species-specific spectral characteristics of a stress response.

Microbiologyopen 2018 Oct 31:e761. Epub 2018 Oct 31.

Behavioural Neuroscience Program, Laurentian University, Sudbury, Ontario, Canada.

Studies by Alexander Gurwitsch in the 1920' s with onion root cells revealed the phenomenon of mitogenetic radiation. Subsequent works by Popp, Van Wijk, Quickenden, Tillbury, and Trushin have demonstrated a link between Gurwitsch's mitogenetic radiation and the biophoton, emissions of light correlated with biological processes. The present study seeks to expand upon these and other works to explore whether biophoton emissions of bacterial cultures is used as an information carrier of environmental stress. Read More

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October 2018
4 Reads

Stable Isotope Labeling of Prodiginines and Serratamolides Produced by Serratia marcescens Directly on Agar and Simultaneous Visualization by Matrix-Assisted Laser Desorption/Ionization Imaging High-Resolution Mass Spectrometry.

Anal Chem 2018 Nov 5;90(22):13167-13172. Epub 2018 Nov 5.

Institute of Environmental Research (INFU), Department of Chemistry and Chemical Biology, Chair of Environmental Chemistry and Analytical Chemistry , TU Dortmund , Otto-Hahn-Straße 6 , 44221 Dortmund , Germany.

Matrix-assisted laser desorption/ionization imaging high-resolution mass spectrometry (MALDI-imaging-HRMS) is an important technique for visualizing the spatial distribution of compounds directly on the surface of organisms such as microorganisms, insects, plants, animals, and human tissues. However, MALDI-imaging-HRMS and the stable isotope labeling approach have never been combined for the detection and simultaneous visualization of labeled and unlabeled compounds, their analogues and derivatives, as well as their precursors. Herein, we present a methodology that labels microbial secondary metabolites directly on agar with stable isotopes and allows concurrent spatial distribution analyses by MALDI-imaging-HRMS. Read More

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November 2018
1 Read

Fosfomycin in severe infections due to genetically distinct pan-drug-resistant Gram-negative microorganisms: synergy with meropenem.

J Antimicrob Chemother 2018 Oct 29. Epub 2018 Oct 29.

Department of Infection Control of Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.

Background: In vitro and clinical studies using parenteral fosfomycin have suggested the possibility of using this drug against infections caused by MDR microorganisms. The aim of this study was to describe a case series of patients treated with fosfomycin who had severe infections caused by pan-drug-resistant Gram-negative bacteria.

Methods: We describe a prospective series of cases of hospitalized patients with infections caused by Gram-negative bacteria resistant to β-lactams and colistin, treated with 16 g of fosfomycin daily for 10-14 days. Read More

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October 2018
2 Reads

The infection of Harmonia axyridis by a parasitic nematode is mediated by entomopathogenic bacteria and triggers sex-specific host immune responses.

Sci Rep 2018 Oct 29;8(1):15938. Epub 2018 Oct 29.

Fraunhofer Institute for Molecular Biology and Applied Ecology, Winchester Strasse 2, D-35394, Giessen, Germany.

The harlequin ladybird Harmonia axyridis is native to Asia but has been introduced into many countries as a biological control agent. It is now considered an invasive pest, threatening the biodiversity of native ladybirds globally, in part because of its superior immune system. H. Read More

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October 2018
6 Reads

First Pediatric Case of Infective Endocarditis Caused by Serratia Liquefaciens.

Int Heart J 2018 Nov 25;59(6):1485-1487. Epub 2018 Oct 25.

Department of Pediatrics and Pediatric Cardiology, Saitama Medical Center, Saitama Medical University.

Infective endocarditis (IE) caused by Serratia liquefaciens has been reported in only 2 adults. We experienced the first pediatric (neonatal) case of IE caused by S. liquefaciens, with mitral valve vegetation 4 days after a palliative heart surgery. Read More

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November 2018
7 Reads
1.130 Impact Factor

Purification and characterization of the thermostable protease produced by Serratia grimesii isolated from channel catfish.

J Sci Food Agric 2018 Oct 25. Epub 2018 Oct 25.

Department of Human Ecology, Food Science and Biotechnology Program, Food Microbiology Laboratory, College of Agricultural and Related Sciences, Delaware State University, Dover, DE, 19901, USA.

Background: Microbial spoilage of fishery products account for significant financial losses yearly on a global-scale. Psychrotrophic spoilage bacteria often secrete extracellular enzymes to break-down surrounding fish tissue, rendering the product unsuitable for human consumption. For better understanding of bacterial spoilage due to enzymatic digestions of fish products, proteases in S. Read More

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October 2018
5 Reads
1.710 Impact Factor

Characterization of a Salmonella Enteritidis bacteriophage showing broad lytic activity against Gram-negative enteric bacteria.

J Microbiol 2018 Dec 25;56(12):917-925. Epub 2018 Oct 25.

Department of Microbiology, School of Medicine, Kyungpook National University, Daegu, 41944, Republic of Korea.

In this study, we sought to isolate Salmonella Enteritidis-specific lytic bacteriophages (phages), and we found a lytic phage that could lyse not only S. Enteritidis but also other Gramnegative foodborne pathogens. This lytic phage, SS3e, could lyse almost all tested Salmonella enterica serovars as well as other enteric pathogenic bacteria including Escherichia coli, Shigella sonnei, Enterobacter cloacae, and Serratia marcescens. Read More

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December 2018
3 Reads
1.439 Impact Factor

Effect of inactivation of luxS gene on the properties of Serratia proteamaculans 94 strain.

Folia Microbiol (Praha) 2018 Oct 25. Epub 2018 Oct 25.

Institute of Molecular Genetics, Russian Academy of Sciences, Kurchatov sq. 2, Moscow, Russia, 123182.

The luxS gene is responsible for the synthesis of AI-2 (autoinducer-2), a signaling molecule that participates in quorum sensing regulation in a large number of bacteria. In this work, we investigated which phenotypes are regulated by luxS gene in Serratia proteamaculans 94, psychrotrophic strain isolated from spoiled refrigerated meat. AI-2 was identified in S. Read More

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October 2018
4 Reads

Comparative in vitro effectiveness of a novel contact lens multipurpose solution on Acanthamoeba castellanii.

J Ophthalmic Inflamm Infect 2018 Oct 24;8(1):19. Epub 2018 Oct 24.

Department of Microbiology and Immunology, Tulane School of Medicine, New Orleans, LA, 70102, USA.

Background: A multipurpose contact lens cleaning solution (MPS) containing novel active ingredients under development was compared to two commercially available MPS solutions for effectiveness against Acanthamoeba isolates.

Methods: The Acanthamoeba isolate A. castellanii was propagated for trophozoite or cyst-containing cultures for the purpose of assessment of effectiveness of each MPS. Read More

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October 2018
1 Read

Host blood-meal source has a strong impact on gut microbiota of Aedes aegypti.

FEMS Microbiol Ecol 2019 Jan;95(1)

Illinois Natural History Survey, University of Illinois at Urbana-Champaign, 1816 S. Oak St., Champaign, IL 61820, USA.

Gut microbial communities of mosquitoes can influence vector susceptibility to pathogens, yet the factors that govern their composition remain poorly understood. We investigated the impact of host blood-meal source on gut microbiota of Aedes aegypti L. Adult mosquitoes were fed on human, rabbit or chicken blood and their gut microbiota compared to those of sugar-fed and newly emerged adults. Read More

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January 2019
4 Reads

Metabolic fingerprints of Serratia liquefaciens under simulated Martian conditions using Biolog GN2 microarrays.

Sci Rep 2018 Oct 24;8(1):15721. Epub 2018 Oct 24.

University of Florida, 505 Odyssey Way, Space Life Sciences Lab, Exploration Park, Merritt Island, FL, 32953, USA.

Microorganisms growing at atmospheric pressures of 0.7 kPa may have a significant impact on the search for life on Mars. Data on their nutrient requirements in a simulated Martian environment are required to ascertain both the potential risk of forward contamination and the potential of past or present habitability of Mars. Read More

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October 2018

KM4 Improves Salt Stress Tolerance in Maize by Regulating Redox Potential, Ion Homeostasis, Leaf Gas Exchange and Stress-Related Gene Expression.

Int J Mol Sci 2018 Oct 24;19(11). Epub 2018 Oct 24.

UMR CNRS 8256 (B2A), IBPS, Université Paris VI, 75005 Paris, France.

High salinity mitigates crop productivity and quality. Plant growth-promoting soil rhizobacteria (PGPR) improve plant growth and abiotic stress tolerance via mediating various physiological and molecular mechanisms. This study investigated the effects of the PGPR strain KM4 on the growth and physiological and molecular responsiveness of maize ( L. Read More

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October 2018
3 Reads
2.860 Impact Factor