Int J Mol Sci 2017 Oct 20;18(10). Epub 2017 Oct 20.
Department of Medical Science, University of Turin, 10126 Turin, Italy.
Platelets have received increasing attention for their role in the pathophysiology of infectious disease, inflammation, and immunity. In sepsis, a low platelet count is a well-known biomarker for disease severity and more recently authors have focused their attention on the active role of platelets in the pathogenesis of multi-organ failure. Septic shock is characterised by a dysregulated inflammatory response, which can impair the microcirculation and lead to organ injury. Read More