29,298 results match your criteria Sentinel Lymph Node Biopsy in Patients With Melanoma
Sentinel Event Alert 2018 Dec(60):1-8
Clinics (Sao Paulo) 2018 Dec 10;73(suppl 1):e550s. Epub 2018 Dec 10.
Cirurgia de Cabeca e Pescoco, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, SP, BR.
Indian J Surg Oncol 2018 Dec 26;9(4):505-510. Epub 2018 Jul 26.
2Department of Radiodiagnosis, Cancer Institute (WIA), Chennai, India.
Clinical assessment of the axilla, especially in early-stage breast cancer, can have a high degree of inaccuracy with over-staging curtailing the use of sentinel node biopsy. Imaging of axilla, using ultrasound ± guided fine needle aspiration cytology (FNAC) can help in better staging. In this study, we aim to compare physical examination and ultrasound of axilla and FNAC and assess their accuracy in preoperative staging of axilla. Read More
Arch Environ Contam Toxicol 2018 Dec 7. Epub 2018 Dec 7.
St. Lawrence River Institute of Environmental Sciences, 2 St. Lawrence Drive, Cornwall, ON, K6H 4Z1, Canada.
Legacy mercury (Hg) sediment deposits are a long-term issue within the St. Lawrence River (Cornwall) area of concern with three depositional areas along the Cornwall, ON waterfront containing sediments that exceed the Ontario Sediment Quality Guidelines for Hg. Assessing the bioavailability of these Hg-contaminated sediments plays a crucial role in evaluating the effectiveness of the Cornwall Sediment Strategy based on a natural recovery approach. Read More
J Neurol Surg Rep 2018 Oct 7;79(4):e93-e97. Epub 2018 Dec 7.
Department of Neurosurgery, Kantonsspital Aarau (KSA), Aarau, Switzerland.
Microsurgical clip ligation is considered a definitive treatment for intracranial aneurysms (IAs), resulting in low rates of local recurrence that range from 0.2 to 0.5% and a latency period that averages about a decade. Read More
Rep Pract Oncol Radiother 2018 Nov-Dec;23(6):503-509. Epub 2018 Jun 12.
Department of Radiation Oncology & Nuclear Medicine, N.N. Petrov Institute Oncology, Leningradskaya 68, 197758 St Petersburg, Russia.
Purpose: To evaluate patterns of lymph flow from primary lesions in patients with cervical cancer and to determine how useful for radiotherapy planning this information can be.
Materials And Methods: SPECT-CT visualization of sentinel (SLN) lymph nodes (LNs) was performed in 36 primary patients with IB-IIB cervical cancer. The acquisition started 120-240 min after 4 peritumoral injections of 99mTc-radiocolloids (150-300 MBq in 0. Read More
Rep Pract Oncol Radiother 2018 Nov-Dec;23(6):495-502. Epub 2018 May 9.
Gynecological Oncology Unit, Barcelona Clinic Hospital, 170 Villaroel St, Barcelona 08036, Spain.
Cervical cancer is the fourth most common cancer in women, and seventh overall. This disease represents a medical, economic and social burden. In early FIGO stage patients (IA, IB1 and IIA1), nodal involvement is the most important prognostic factor. Read More
Gac Med Mex 2018 ;154(6):712-715
Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Oncología, Ciudad de México, México.
Most patients with cutaneous melanoma present with clinical stage 1 at diagnosis, i.e., with no evidence of lymph node or systemic metastases. Read More
Curr Sports Med Rep 2018 Dec;17(12):419-424
Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN.
Youth athletics can provide numerous benefits to children. Until recently, athletics have been relatively free from scrutiny over the ways they put participants at risk. While it was often disregarded in early childhood research, athletics emerged as an avenue of child abuse in the 1980s. Read More
J Proteomics 2018 Dec 6. Epub 2018 Dec 6.
Laboratoire Innovations technologiques pour la Détection et le Diagnostic (Li2D), Service de Pharmacologie et Immunoanalyse (SPI), CEA, INRA, F-30207 Bagnols-sur-Cèze, France. Electronic address:
Anthropogenic pollutants are found worldwide. Their fate and effects on human and ecosystem health must be appropriately monitored. Today, ecotoxicology is focused on the development of new methods to assess the impact of pollutant toxicity on living organisms and ecosystems. Read More
Chemosphere 2018 Dec 1;219:15-27. Epub 2018 Dec 1.
Department of Pharmacology, Federal University of Paraná, P.O. Box 19031, 81530-980, Curitiba, Paraná, Brazil. Electronic address:
This study combined data of the concentrations of metals, polycyclic aromatic hydrocarbons (PAHs) and pharmaceuticals and personal hygiene products (PPCPs) in the sediments and the biological responses of the Atherinella brasiliensis fish in two different sites and climate seasons in the Estuarine-Lagoon Complex of Iguape-Cananéia, Southeast Brazil. The presence of metals, PAHs, and PPCPs were observed in the sediments demonstrating the contamination throughout the system with contributions of sewage and residues disposal, oil and combustion of biomass and fossil fuels. Higher contaminations were identified in the point of greater human presence (C - Cananéia City), especially during the cold-dry season. Read More
J Plast Reconstr Aesthet Surg 2018 Nov 29. Epub 2018 Nov 29.
Department of Plastic, Reconstructive and Aesthetic Surgery, University Hospital "Dubrava", Av. G. Šuška 6, Zagreb, Croatia. Electronic address:
J Infect 2018 Dec 5. Epub 2018 Dec 5.
National Centre for Immunisation Research and Surveillance of Vaccine Preventable Diseases (NCIRS), Children's Hospital at Westmead, Sydney, Australia; Discipline of Child and Adolescent Health, University of Sydney, Sydney, Australia; Children's Hospital at Westmead, Sydney, Australia.
Objectives: To examine the impact of Australia's single dose infant varicella vaccination program, we assessed single dose varicella vaccine effectiveness (VE) in preventing hospitalised disease using two methods.
Methods: Clinically confirmed varicella cases from the Paediatric Active Enhanced Disease Surveillance (PAEDS) sentinel network were age-matched to 20 controls obtained from the Australian Immunisation Register. Conditional logistic regression models were used to estimate VE and compared with estimates obtained using our second approach. Read More
Clin Radiol 2018 Dec 6. Epub 2018 Dec 6.
breast unit, University of Dundee, Mailbox 4, Level 6, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK.
Aims: To assess the feasibility and acceptability of large-gauge percutaneous removal of the axillary sentinel lymph node (SLN) using dual gamma probe and ultrasound guidance.
Materials And Methods: Technetium nanocolloid was administered the day before surgery. On the day of surgery, potential SLNs were identified with gamma probe and ultrasound scanning. Read More
Eur J Surg Oncol 2018 Dec 1. Epub 2018 Dec 1.
Veneto Institute of Oncology IOV-IRCCS, Department of Surgery, Oncology and Gastroenterology (DISCOG), University of Padova, Via Gattamelata, 64, 35128, Padova, Italy.
Background: The indication to sentinel node biopsy (SNB) for thin melanomas (Breslow <1 mm) is still subject to controversies. The aim of this paper is to review all SNB performed for thin melanoma and to analyze factors related to lymphatic metastasis. Moreover, the diagnostic performance of the 5th, 6th, 7th and 8th AJCC classifications for cutaneous melanoma were investigated. Read More
J Plast Reconstr Aesthet Surg 2018 Nov 23. Epub 2018 Nov 23.
Department of Plastic and Reconstructive Surgery, Royal Preston Hospital, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK. Electronic address:
Scand J Urol 2018 Dec 11:1-8. Epub 2018 Dec 11.
a Department of Urology, The Netherlands Cancer Institute , Amsterdam , The Netherlands.
Objective: To investigate the rate of occult SN metastases, oncological outcome, and association of recurrence with the pattern of lymphatic tumour drainage in RCC.
Materials And Methods: A pooled RCC sub-group analysis was conducted of secondary endpoints from a published feasibility and a phase II prospective single-arm SN study to investigate oncological outcome. Patients with cT1-3 (<10 cm) cN0M0 RCC of any sub-type were enrolled. Read More
Am J Obstet Gynecol 2018 Dec 3. Epub 2018 Dec 3.
Northwestern University, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Chicago, IL, USA; Robert H Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL; Center for Healthcare Studies, Institute for Public Health in Medicine, Chicago, IL.
Background: In patients with endometrial cancer sentinel lymphadenectomy is used to accurately prognosticate extent of disease and has been proposed as a method to decrease the incidence of medical and surgical complications associated with more extensive lymphadenectomy. It is unknown if patients who undergo traditional lymphadenectomy experience major postoperative complications at the same rates as those who undergo sentinel lymphadenectomy or those who do not undergo lymphadenectomy.
Objective: To compare the incidence of major postoperative complications among endometrial cancer patients undergoing total laparoscopic hysterectomy with traditional lymphadenectomy versus sentinel or no lymphadenectomy. Read More
Breast Cancer 2018 Dec 5. Epub 2018 Dec 5.
Department of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Hospital, Kagoshima, Japan.
Apocrine papillary lesion (APL) is difficult to diagnose as benign or malignant. We experienced an APL remaining in the body for 22 years. We present a case of a 71-year-old woman who had undergone excisional biopsy 22 years previously at the first hospital that she visited. Read More
Aust N Z J Psychiatry 2018 Dec 5:4867418815977. Epub 2018 Dec 5.
1 School of Medicine and Public Health, Faculty of Health and Medicine, University of Newcastle, Callaghan, NSW, Australia.
Background:: The Australian Institute of Health and Welfare has reported an increased rate of hospital-treated intentional self-harm in young females (2000-2012) in Australia. These reported increases arise from institutional data that are acknowledged to underestimate the true rate, although the degree of underestimation is not known.
Objective:: To consider whether the reported increase in young females' hospital-treated intentional self-harm is real or artefactual and specify the degree of institutional underestimation. Read More
Bioconjug Chem 2018 Dec 3. Epub 2018 Dec 3.
For SLN lymph node biopsy (SLNB), the SLN mapping has become a standard of care procedure that can accurately locate the micrometastases disseminated from primary tumor sites to the regional lymph nodes. The broad array of SLN mapping has prompted the development of a wide range of SLN tracers, rationally designed for noninvasive, and high-resolution imaging of SLNs. At present, conventional SLN imaging probes (blue dyes, radiocolloids and few other small-molecular dyes) although serves the clinical needs, these are often associated with major issues such as insufficient accumulation in SLN, short retention time, staining of the surgical field and other adverse side effects. Read More
J Surg Oncol 2018 Dec 3. Epub 2018 Dec 3.
Second Department of General Surgery, Baoding No. 1 Central Hospital, Baoding, Hebei, China.
J Surg Oncol 2018 Dec 3. Epub 2018 Dec 3.
Department of Gynaecology and Obstetrics, University Hospital Pilsen, Charles University, Prague, Czech Republic.
Background And Objectives: Utilisation of the one-step nucleic acid amplification (OSNA) molecular biology method for the detection of the metastatic involvement of sentinel lymph nodes (SLNs) in endometrial cancer (EC) patients. A comparison with histopathological ultrastaging and a description of the clinical consequences.
Methods: Surgically treated EC patients underwent detection of SLNs. Read More
J Surg Oncol 2018 Dec 3. Epub 2018 Dec 3.
Department of Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.
Background: Sentinel lymph node biopsy (SLNB) is not routinely recommended for thin melanoma. However, it is considered when high-risk features, clinicopathological, or sociodemographic, are present. It was our objective to evaluate the impact of travel distance on decision-making for SLNB in thin melanoma. Read More
J Travel Med 2018 Dec 3. Epub 2018 Dec 3.
Tropical Disease Unit, Toronto General Hospital, Canada.
Nucl Med Commun 2018 Nov 29. Epub 2018 Nov 29.
Department of Medico-biological Science, North-West State Medical University named after I.I. Mechnikov, Saint Petersburg, Russia.
Aim: The aim of the present study was to determine the accuracy of single-photon emission computed tomography-computed tomography (SPECT-CT) with technetium-99m-sestamibi (Tc-MIBI) for detecting multiple (>2 nodes) axillary lymph node involvement in patients with breast cancer (BC).
Patients And Methods: A total of 184 women with BC were examined. Clinically, axillary lymph nodes were classified as N0 in all cases. Read More
Lancet Oncol 2018 Dec;19(12):e720-e725
Department of Dermatology and Comprehensive Cancer Centre, University Hospital Essen, Essen, Germany.
It is important to differentiate between two concepts of adjuvant therapy in melanoma-what we have come to call late adjuvant and early adjuvant therapy. Early adjuvant therapy is defined as a medical intervention that is done after resection of a primary melanoma to eradicate possible undetectable minimal residual disease, whereas late adjuvant therapy is done when an overt metastatic disease (nodal or visceral) has been completely resected, to control disease better than if the same treatment were given at a later time, in the presence of multiple metastases. Early adjuvant therapy is thus a preventive treatment strategy, whereas late adjuvant therapy aims at anticipating treatment of metastatic disease. Read More
J Dtsch Dermatol Ges 2018 Dec 3. Epub 2018 Dec 3.
Centre for Dermato-oncology, University Department of Dermatology, Eberhard Karls University, Tübingen, Germany.
For decades, melanoma surgery has been guided by the Halstedian concept of stepwise metastasis, first into the lymph nodes and subsequently to distant sites. Early complete lymph node dissection (CLND) was therefore recommended in order to improve survival. Four large prospective randomized trials failed to show any survival benefit of CLND in comparison to observation alone. Read More
Ann Surg Oncol 2018 Nov 30. Epub 2018 Nov 30.
Breast Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Background/objective: Recent prospective trials support the use of sentinel lymph node biopsy (SLNB) in breast cancer patients after neoadjuvant chemotherapy (NAC) with a lower false-negative rate if three or more sentinel lymph nodes (SLNs) are identified. In this study, we investigated whether the pre-NAC axillary lymph node status influences the number of SLNs identified.
Methods: Stage I-III breast cancer patients who received NAC and underwent SLNB from May 2014 to April 2016 were identified from an institutional prospective database. Read More
J Nucl Med 2018 Nov 30. Epub 2018 Nov 30.
Leiden University Medical Center, Netherlands.
For radical resection of squamous cell carcinoma of the oral cavity, a tumor free margin of at least 5 mm is required. Unfortunately, establishing in-depth margins is a surgical conundrum. Knowing the hybrid sentinel node (SN) tracer indocyanine green (ICG)-Tc-nanocolloid generates temporary tattoo-like markings at the site of administration, we studied the ability of applying this tracer for tumor-margin demarcation combined with SN biopsy. Read More
Mar Pollut Bull 2018 Dec 11;137:96-103. Epub 2018 Oct 11.
Institute for Marine and Antarctic Studies, University of Tasmania, 20 Castray Esplanade, Battery Point, Tasmania 7004, Australia; Bird Group, Department of Life Sciences, The Natural History Museum, Akeman Street, Tring, Hertfordshire HP23 6AP, United Kingdom.
Marine debris is pervasive worldwide, and affects biota negatively. We compared the characteristics of debris incorporated within brown booby (Sula leucogaster) nests throughout their pantropical distribution by assessing the type, colour and mass of debris items within nests and in beach transects at 18 sites, to determine if nests are indicators of the amount of debris in local marine environments. Debris was present in 14. Read More
Mar Pollut Bull 2018 Dec 15;137:688-694. Epub 2018 Nov 15.
OLMAN-RL, Faculté Pluridisciplinaire de Nador (FPN), Université Mohammed 1er, B.P: 300, Selouane, 62700, Nador, Morocco. Electronic address:
Heavy metal concentrations of Cd, Cr, Cu, Fe, Ni, Zn, Co, and Pb were investigated in soft tissues of Mytilus galloprovincialis coming from an aquaculture farm in Cala Iris sea of AlHoceima. Mytilus galloprovincialis were collected monthly during the period January to December 2016. The seasonal variations were affected significantly the concentrations of metals (Cd, Fe and Cr) in M. Read More
Top Companion Anim Med 2018 Dec 20;33(4):136-140. Epub 2018 Aug 20.
Department of Veterinary Clinical Sciences, Ohio State University College of Veterinary Medicine, Columbus, OH, USA. Electronic address:
Degenerative joint disease of the stifle is a common canine osseous pathology. Early degenerative changes may show mild mineral proliferation of periarticular margins with soft tissue, resulting in joint distension. If the joint is chronically unstable, osseous changes become more complex. Read More
J Surg Res 2019 Jan 23;233:149-153. Epub 2018 Aug 23.
Department of Surgery, Sidney Kimmel Medical College, Thomas Jefferson University, Surgery, Philadelphia, Pennsylvania. Electronic address:
Background: Sentinel lymph node biopsy (SLNB) is an important adjunct in the staging of patients with melanoma. Preoperative lymphoscintigraphy with radiolabeled isotopes is essential to localize sentinel nodes for removal. Our study compared the effectiveness of Lymphoseek to standard sulfur colloids in patients with melanoma undergoing SLNB. Read More
J Plast Reconstr Aesthet Surg 2018 Nov 23. Epub 2018 Nov 23.
Blenheim Head and Neck Unit, Churchill Hospital, Old Road, Headington, Oxford OX3 7LE, United Kingdom.
Epidemiol Infect 2018 Dec 3:1-7. Epub 2018 Dec 3.
Section of Epidemiology, Department of Public Health,University of Copenhagen,Copenhagen,Denmark.
It has been reported that foetal death follows a seasonal pattern. Influenza virus infection has been postulated as one possible contributor to this seasonal variation. This ecological study explored the temporal association between the influenza activity and the frequency of foetal death. Read More
Rheumatology (Oxford) 2018 Dec 4. Epub 2018 Dec 4.
Department of Clinical Immunology and Rheumatology, Amsterdam Rheumatology and Immunology Center.
Objectives: Synovial mast cells contain IL-17A, a key driver of tissue inflammation in SpA. A recent in vitro study showed that tissue-derived mast cells can capture and release exogenous IL-17A. The present study aimed to investigate if this mechanism could contribute to tissue inflammation in SpA. Read More
J Insect Sci 2018 Nov 1;18(6). Epub 2018 Nov 1.
Departamento de Botánica y Zoología, CUCBA, Universidad de Guadalajara, Las Agujas, Zapopan, Jalisco, México.
Little is known about Dalbulus maidis (DeLong) egg parasitoids within maize fields, in the edge zones that surround these fields, and the parasitism on D. maidis eggs oviposited on different maize varieties. The objectives of the present study were first to understand which egg parasitoid species attack D. Read More
Plast Reconstr Surg 2018 Nov 27. Epub 2018 Nov 27.
From the Department of Diagnostic and Clinical Medicine and of Public Health, Institute of Pathology, University Hospital of Modena, Modena (MO), Italy.
Plast Reconstr Surg 2018 Nov 27. Epub 2018 Nov 27.
Division of Plastic and Reconstructive Surgery, Dalhousie University, Halifax, Nova Scotia, Canada Division of Plastic and Reconstructive Surgery, McMaster University, Hamilton, Ontario, Canada.
Epidemiol Infect 2018 Dec 5:1-9. Epub 2018 Dec 5.
International Livestock Research Institute,Nairobi,Kenya.
We implemented a cross-sectional study in Tana River County, Kenya, a Rift Valley fever (RVF)-endemic area, to quantify the strength of association between RVF virus (RVFv) seroprevalences in livestock and humans, and their respective intra-cluster correlation coefficients (ICCs). The study involved 1932 livestock from 152 households and 552 humans from 170 households. Serum samples were collected and screened for anti-RVFv immunoglobulin G (IgG) antibodies using inhibition IgG enzyme-linked immunosorbent assay (ELISA). Read More
Environ Sci Pollut Res Int 2018 Dec 4. Epub 2018 Dec 4.
Istituto Zooprofilattico Sperimentale del Mezzogiorno (IZSM), Portici, 80055, Naples, Italy.
The aim of the present study was to assess the concentrations of lead (Pb) and cadmium (Cd) in the liver and kidney from stray dogs (Canis lupus familiaris) and cats (Felis catus) found dead between 2014 and 2017 in the city of Naples and its surrounding areas. These organs from 290 dogs and 88 cats were collected after ordinary necropsy of stray animals. Heavy metal concentrations were determined by using atomic absorption spectrophotometry (AAS). Read More
J Thyroid Res 2018 1;2018:1718284. Epub 2018 Nov 1.
Thyroid Clinic, General Surgery Service, Hospital General de México, Mexico City, Mexico.
Background: Optimal neck lymphadenectomy in patients with papillary thyroid cancer (PTC) and microscopic lymph node metastasis needs to be defined in order to aid surgeons in their decision about the best way to proceed in these cases.
Methods: Patients who underwent total thyroidectomy and lymphadenectomy at levels IIa to VI were divided into two groups: Group 1 (G1) with macroscopic metastasis detected before surgery and Group 2 (G2) with microscopic metastasis detected in sentinel node during surgery. Odds ratio (OR) was computed for age, sex, tumor size, multicentricity, capsular invasion, vascular/lymphatic permeation, and nodes with metastasis. Read More
Trials 2018 Dec 4;19(1):667. Epub 2018 Dec 4.
Breast Center, University Hospital Basel, Spitalstrasse 21, 4031, Basel, Switzerland.
Background: Complete lymph node removal through conventional axillary dissection (ALND) has been standard treatment for breast cancer patients for almost a century. In the 1990s, however, and in parallel with the advent of the sentinel lymph node (SLN) procedure, ALND came under increasing scrutiny due to its association with significant patient morbidity. Several studies have since provided evidence to suggest omission of ALND, often in favor of axillary radiation, in selected clinically node-negative, SLN-positive patients, thus supporting the current trend in clinical practice. Read More
Vector Borne Zoonotic Dis 2018 Dec 4. Epub 2018 Dec 4.
1 Laboratório de Entomologia, Fundação Oswaldo Cruz - Fiocruz Rondônia, Porto Velho, Rondônia, Brazil .
This study examined sand fly diversity and the natural infection of sand flies by Leishmania in three localities in Rondônia State: Santo Antônio and São Vicente farm, which are anthropized environments, and the Jamari FLONA, which has not been anthropized. Sand flies were collected in canopies and at ground level using CDC light traps and BG-Sentinel CO traps. Female sand flies were grouped into pools that were subjected to DNA extraction and the samples were subjected to PCR to detect and identify Leishmania. Read More
J Biophotonics 2018 Dec 3:e201800357. Epub 2018 Dec 3.
School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore.
Photoacoustic imaging is a non-invasive imaging technique having the advantages of high optical contrast and good acoustic resolution at improved imaging depths. Light transport in biological tissues is mainly characterized by strong optical scattering and absorption. Photoacoustic microscopy is capable of achieving high resolution images at greater depth compared to conventional optical microscopy methods. Read More
Breast J 2018 Dec 3. Epub 2018 Dec 3.
Department of Surgery, Emory University, Atlanta, Georgia.
Introduction: Breast conserving surgery (BCS) has a postoperative morbidity up to 30%. We report the feasibility of a single-incision approach for tumor excision and axillary sentinel node biopsy (SNB) sampling intended to minimize patient morbidity and complications.
Materials And Methods: A tertiary surgical oncology single surgeon database was retrospectively reviewed for all patients undergoing BCS and SNB between January 2013 and December 2015. Read More
EJNMMI Res 2018 Dec 3;8(1):105. Epub 2018 Dec 3.
Department of Urology, The Netherlands Cancer Institute, Postbus 90203, 1006 BE, Amsterdam, The Netherlands.
Background: Sentinel lymph node biopsy (SLNB) after intratumoral injection of Tc labeled nanocolloid and imaging with scintigraphy and SPECT/CT in renal tumors is feasible. However, sentinel lymph node (SN) non-detection rate with scintigraphy and SPECT/CT is high. The aim of the study was to determine factors affecting non-visualization (NV) of SN imaging in renal tumors. Read More
BMC Infect Dis 2018 Dec 3;18(1):609. Epub 2018 Dec 3.
WHO Collaborating Centre for Gonorrhea and other STIs, Örebro University, Örebro, Sweden.
Background: The European Gonococcal Antimicrobial Surveillance Programme (Euro-GASP) performs annual sentinel surveillance of Neisseria gonorrhoeae susceptibility to therapeutically relevant antimicrobials across the European Union/European Economic Area (EU/EEA). We present the Euro-GASP results from 2016 (25 countries), linked to patient epidemiological data, and compared with data from previous years.
Methods: Agar dilution and minimum inhibitory concentration (MIC) gradient strip methodologies were used to determine the antimicrobial susceptibility (using EUCAST breakpoints) of 2660 N. Read More
PLoS Negl Trop Dis 2018 Nov 30;12(11):e0006924. Epub 2018 Nov 30.
Malaria Pathogenesis Unit, Eijkman Institute for Molecular Biology, Jakarta, Indonesia.
The discovery of the life-threatening zoonotic infection Plasmodium knowlesi has added to the challenges of prompt and accurate malaria diagnosis and surveillance. In this study from Aceh Province, Indonesia, a malaria elimination setting where P. knowlesi endemicity was not previously known, we report the laboratory investigation and difficulties encountered when using molecular detection methods for quality assurance of microscopically identified clinical cases. Read More