3,459 results match your criteria Seizure - European Journal of Epilepsy[Journal]


Factors associated with seizure-related motor vehicle accidents among patients with epilepsy in West China.

Seizure 2019 Jan 30;66:42-46. Epub 2019 Jan 30.

Department of Neurology, West China Hospital, Sichuan University, No. 37 Guoxue Road, Chengdu, Sichuan, 610041, People's Republic of China. Electronic address:

Purpose: This study was conducted to investigate the relevant demographics and clinical factors contributing to seizure-related motor vehicle accidents in west China.

Methods: All driving patients who visited our epilepsy clinic in the West China Hospital, between October 2012 and October 2016, were invited to participate. Data on social demographics, clinical features, and motor vehicle accidents were collected during structured interviews. Read More

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http://dx.doi.org/10.1016/j.seizure.2019.01.028DOI Listing
January 2019

Ictal biting injuries in the epilepsy monitoring unit, a cohort study of incidence and semiological significance.

Seizure 2019 Feb 14;66:39-41. Epub 2019 Feb 14.

Epilepsy Center, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44106, United States of America.

Purpose: Oral biting injuries are widely recognized complications of seizures. Value in differentiating epileptic vs paroxysmal non-epileptic seizures is well demonstrated, but frequency and semiological value are poorly described. We aimed to evaluate frequency in an epilepsy monitoring unit setting as well as semiological value. Read More

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http://dx.doi.org/10.1016/j.seizure.2019.02.005DOI Listing
February 2019

CADASIL presenting with focal and generalised epilepsy due to a novel NOTCH3 mutation.

Seizure 2019 Jan 30;66:36-38. Epub 2019 Jan 30.

Department of Neurology, Auckland City Hospital, Private Bag 92024, Auckland 1142, New Zealand.

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http://dx.doi.org/10.1016/j.seizure.2019.01.026DOI Listing
January 2019

Cerebrovascular disease burden in late-onset non-lesional focal epilepsy.

Seizure 2019 Feb 8;66:31-35. Epub 2019 Feb 8.

Epilepsy Unit, Neurology Department, Vall d'Hebron University Hospital, Autonomous University of Barcelona, Barcelona, Spain. Electronic address:

Purpose: Late-onset non-lesional focal epilepsy, defined as new-onset seizures in patients older than 60 years, is diagnosed increasingly more often in relation to aging of the population. It has been attributed mainly to occult cerebral small vessel disease (SVD), although high levels of evidence to support this notion are lacking. This study aimed to evaluate the burden of leukoaraiosis, a marker of cerebral SVD, and hippocampal atrophy in patients with late-onset epilepsy (LOE). Read More

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http://dx.doi.org/10.1016/j.seizure.2019.02.004DOI Listing
February 2019

Gene mutational analysis in a cohort of Chinese children with unexplained epilepsy: Identification of a new KCND3 phenotype and novel genes causing Dravet syndrome.

Seizure 2019 Jan 28;66:26-30. Epub 2019 Jan 28.

Department of Pediatrics, Peking University First Hospital, Beijing 100034, China. Electronic address:

Purpose: This study aimed to investigate the genetic etiology of epilepsy in a cohort of Chinese children.

Methods: Targeted next-generation sequencing (NGS) was performed for 120 patients with unexplained epilepsy, including 71 patients with early-onset epileptic encephalopathies, and 16 patients with Dravet syndrome (including three patients with a Dravet-like phenotype) but without SCN1A pathogenic variants.

Results: Pathogenic variants of 14 genes were discovered in 22 patients (18%). Read More

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http://dx.doi.org/10.1016/j.seizure.2019.01.025DOI Listing
January 2019

Natural history of patients with psychogenic nonepileptic seizures.

Seizure 2019 Feb 11;66:22-25. Epub 2019 Feb 11.

Neuroscience Research Center, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:

Purpose: The purpose of this study was to investigate the long-term outcome of patients with psychogenic nonepileptic seizures (PNES), who never visited a psychologist and never received a proper therapy for their condition (due to lack of resources). We also aimed to investigate factors potentially associated with the outcome in these patients.

Methods: We studied all patients with PNES, who were admitted to the epilepsy monitoring unit at the Shiraz Comprehensive Epilepsy Center, from 2008 until 2013. Read More

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http://dx.doi.org/10.1016/j.seizure.2019.02.006DOI Listing
February 2019

Risk factors for seizures after cranioplasty.

Seizure 2018 Dec 19;66:15-21. Epub 2018 Dec 19.

Departments of Neurology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan. Electronic address:

Purpose: Cranioplasty can improve a patient's psychosocial and cognitive functions after decompressive craniectomy, however seizures are a common complication after cranioplasty. The risk factors for early and late seizures after cranioplasty are unclear. This study is to evaluate the risk factors for early and late seizure after cranioplasty. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10591311183055
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http://dx.doi.org/10.1016/j.seizure.2018.12.016DOI Listing
December 2018
1 Read

A novel truncating mutation of dock7 gene with an early-onset non-encephalopathic epilepsy.

Seizure 2019 Jan 16;66:12-14. Epub 2019 Jan 16.

Marmara University, Medical Faculty, Department of Neuroradiology, Pendik, Istanbul, Turkey.

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http://dx.doi.org/10.1016/j.seizure.2019.01.010DOI Listing
January 2019

Epileptic seizure detection using cross-bispectrum of electroencephalogram signal.

Seizure 2019 Feb 4;66:4-11. Epub 2019 Feb 4.

Hakim Sabzevari University, Sabzevar 397, Iran. Electronic address:

Purpose: The automatic detection of epileptic seizures in EEG data from extended recordings can make an important contribution to the diagnosis of epilepsy as it can efficiently reduce the workload of medical staff.

Methods: This paper describes how features based on cross-bispectrum can help with the detection of epileptic seizure activity in EEG data. Features were extracted from multi-channel intracranial EEG (iEEG) data from the Freiburg iEEG recordings of 21 patients with focal epilepsy. Read More

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http://dx.doi.org/10.1016/j.seizure.2019.02.001DOI Listing
February 2019

Retinoencephalopathy with occipital lobe epilepsy in an OPA-1 mutation carrier.

Seizure 2019 Jan 30;66:1-3. Epub 2019 Jan 30.

Department of Epileptology, University of Bonn Hospital, Bonn, Germany; Institute of Experimental Epileptology and Cognition Research, University Bonn, Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.seizure.2019.01.029DOI Listing
January 2019
2.059 Impact Factor

Switching from traditional sodium channel blockers to lacosamide in patients with epilepsy.

Seizure 2019 Feb 30;65:172-175. Epub 2019 Jan 30.

Department of Neurology, Inha University Hospital, Incheon, South Korea. Electronic address:

Purpose: Lacosamide (LCM) is a recently developed sodium channel blocker (SCB), which acts mainly on the slow activation state in sodium channels. Although LCM shares a range of dose-dependent adverse effects with traditional SCBs, it has several advantages in that it does not induce hepatic drug metabolizing enzymes and has less risk of drug interactions and idiosyncratic adverse effects.

Methods: We retrospectively analyzed the efficacy and tolerability of switching from traditional SCBs to LCM. Read More

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http://dx.doi.org/10.1016/j.seizure.2019.01.027DOI Listing
February 2019
2.059 Impact Factor

Seizure outcome and epilepsy patterns in patients with cerebral palsy.

Seizure 2019 Feb 4;65:166-171. Epub 2019 Jan 4.

Neurology Unit, Paediatrics Department, Mansoura University Children Hospital, Mansoura, Egypt.

Purpose: The aim of the present study was to investigate epilepsy patterns and outcomes in patients with cerebral palsy (CP) and identify the variables that determine remission.

Methods: This was a retrospective cohort study. We followed 107 CP patients aged 1-16 years with newly diagnosed epilepsy. Read More

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http://dx.doi.org/10.1016/j.seizure.2019.01.003DOI Listing
February 2019
2 Reads

Seizures in Children with HIV infection in South Africa: A retrospective case control study.

Seizure 2019 Feb 28;65:159-165. Epub 2019 Jan 28.

University of Cape Town Neuroscience Institute, Faculty of Health Sciences, Anzio Road, Observatory, Cape Town 7295 South Africa; Division of Developmental Paediatrics, Department of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, University of Cape Town, Klipfontein Road, Rondebosch, Cape Town, 7700 South Africa. Electronic address:

Purpose: Data relating to the role that Human immunodeficiency virus (HIV) contributes towards seizures in HIV-infected children is limited. The management of seizures in this group is complex due to potential interactions between antiseizure medication and antiretroviral therapies. This study explores the seizure semiology and course of a population of affected children based on questions raised from a previous epidemiological study. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10591311183041
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http://dx.doi.org/10.1016/j.seizure.2019.01.023DOI Listing
February 2019
4 Reads

Diagnostic usefulness of arterial spin labeling in MR negative children with new onset seizures.

Seizure 2019 Feb 27;65:151-158. Epub 2019 Jan 27.

Department of Pediatric, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea. Electronic address:

Purpose: Arterial spine labeling (ASL) magnetic resonance imaging (MRI) is the non-invasive measurement of cerebral blood flow that can localize the seizure focus in patients with epilepsy. The aim of this study was to identify its utility for localizing the seizure focus in children with no structural lesion on MRI.

Methods: Forty-three consecutive children who underwent electroencephalography (EEG) and structural MRI, along with ASL for evaluation of newly developed seizures, were included. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10591311183070
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http://dx.doi.org/10.1016/j.seizure.2019.01.024DOI Listing
February 2019
3 Reads

Surgical techniques: Stereoelectroencephalography-guided radiofrequency-thermocoagulation (SEEG-guided RF-TC).

Seizure 2019 Jan 25. Epub 2019 Jan 25.

Department of Neurosurgery, Neurology & Neurosurgery Hospital Pierre Wertheimer, Hospices Civils de Lyon, France; University of Lyon, Faculty of medicine Claude Bernard, Lyon, France; NEUROPAIN team, Lyon Neuroscience Research Center, INSERM U1028, CNRS, 5292, Lyon, France.

Stereoelectroencephalography-guided radiofrequency-thermocoagulation (SEEG-guided RF-TC) consists of coupling SEEG investigation with RF-TC stereotactic lesioning directly through the recording electrodes. In this systematic review the surgical technique, indications, and outcomes are described. Maximum accuracy is reached when a frame-based procedure with a robotic assistance and a per-operative vascular X-ray imaging are performed. Read More

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http://dx.doi.org/10.1016/j.seizure.2019.01.021DOI Listing
January 2019

Sudden cardiac death in a patient with LGI1 antibody-associated encephalitis.

Seizure 2019 Feb 25;65:148-150. Epub 2019 Jan 25.

IRCCS Istituto delle Scienze Neurologiche di Bologna, Italy; Department of Experimental Diagnostic and Specialty Medicine (DIMES), University of Bologna, Italy.

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http://dx.doi.org/10.1016/j.seizure.2019.01.013DOI Listing
February 2019
1 Read

Dramatic presentations in psychogenic nonepileptic seizures.

Seizure 2019 Feb 24;65:144-147. Epub 2019 Jan 24.

Neuroscience Research Center, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:

Purpose: The aim of this study was to investigate the frequency of dramatic presentations of psychogenic nonepileptic seizures (PNES) (i.e., urine incontinence and ictal injury) and to characterize the patients' historical risk factors that may be associated with such dramatic manifestations. Read More

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http://dx.doi.org/10.1016/j.seizure.2019.01.019DOI Listing
February 2019

Refractory status epilepticus in adults admitted to ITU in Glasgow 1995-2013 a longitudinal audit highlighting the need for action for provoked and unprovoked status epilepticus.

Seizure 2019 Feb 14;65:138-143. Epub 2019 Jan 14.

Department of Neurology, Institute of Neurosciences, Queen Elizabeth University Hospital, Glasgow, G51 4TF, United Kingdom; School of Medicine, Wolfson Medical School Building, University of Glasgow, Glasgow, G12 8QQ, United Kingdom. Electronic address:

Purpose: Our primary objective was to determine incidence of status epilepticus in adults admitted to 5 ITU settings in Glasgow over 18 years. We wanted to investigate if there are any change in causes and outcomes of SE over last decade. We also compared outcomes of De Novo statuts Epilpeticus (DNSE) and Stauts Epilepticus in patients with previous Epilepsy (SEPE). Read More

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http://dx.doi.org/10.1016/j.seizure.2019.01.011DOI Listing
February 2019

Chewing induced reflex seizures ("eating epilepsy") and eye closure sensitivity as a common feature in pediatric patients with SYNGAP1 mutations: Review of literature and report of 8 cases.

Seizure 2019 Feb 22;65:131-137. Epub 2018 Dec 22.

Paracelsus Medical University, Strubergasse 21, 5020 Salzburg, Austria; Hospital for Neuropediatrics and Neurological Rehabilitation, Epilepsy Center for Children and Adolescents, Krankenhausstr. 20, 83569 Vogtareuth, Germany.

Purpose: Heterozygous SYNGAP1 gene mutations have been associated with several forms of idiopathic generalized epilepsy, autism spectrum disorders and delay of psychomotor development. We report eight patients with a SYNGAP1 mutation and chewing/eating induced reflex seizures as new phenotype and compare them to other patients with eating epilepsy and genetic mutations.

Methods: Presentation of clinical and anamnestic features and retrospective analysis of Video-EEG data of a 4 year old index patient with SYNGAP1 mutation and chewing /eating induced seizures. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10591311183046
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http://dx.doi.org/10.1016/j.seizure.2018.12.020DOI Listing
February 2019
3 Reads

"Breath holding spells" in a child with SCN8A-related epilepsy: Expanding the clinical spectrum.

Seizure 2019 Feb 23;65:129-130. Epub 2019 Jan 23.

Epilepsy Program, Division of Neurology, The Hospital for Sick Children, M5G 1X8 Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.seizure.2019.01.020DOI Listing
February 2019
4 Reads

Sleep disturbances in patients with psychogenic non-epileptic seizures: Is it all subjective? A prospective pilot study of sleep-wake patterns.

Seizure 2019 Feb 17;65:124-128. Epub 2019 Jan 17.

Brigham and Women's Hospital, Department of Neurology, Harvard Medical School, Boston, MA, USA. Electronic address:

Purpose: Patients with psychogenic non-epileptic seizures (PNES) frequently complain of poor sleep, yet there are few and inconsistent data supporting objective sleep disturbances in this population. In this prospective observational study, we aimed to compare objective and subjective sleep-wake patterns in patients with PNES with those with epilepsy.

Methods: Subjects were recruited through the Brigham and Women's Epilepsy Monitoring Unit (EMU) over a 6-month period, and were diagnosed as having PNES or epilepsy by experts using video-electroencephalography (v-EEG). Read More

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http://dx.doi.org/10.1016/j.seizure.2019.01.016DOI Listing
February 2019
2 Reads

Different types of suppression-burst patterns in patients with epilepsy of infancy with migrating focal seizures (EIMFS).

Seizure 2019 Feb 18;65:118-123. Epub 2019 Jan 18.

National Epilepsy Center, NHO Shizuoka Institute of Epilepsy and Neurological Disorders, 886 Urushiyama, Aoi-ku, Shizuoka-shi, Shizuoka, 420-8688, Japan.

Purpose: In rare cases, patients with epilepsy of infancy withmigrating focal seizures (EIMFS) exhibit suppression-burst (SB) patterns on electroencephalography (EEG), similar to the findings observed in patients with Ohtahara syndrome and early myoclonic encephalopathy. In this report, we discuss six cases of EIMFS in which patients exhibited two types of SB patterns.

Methods: We evaluated six patients with EIMFS who had been admitted to the NHO Shizuoka Institute of Epilepsy and Neurological Disorders between 2011 and 2018. Read More

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http://dx.doi.org/10.1016/j.seizure.2019.01.009DOI Listing
February 2019
1 Read

Comparing the efficacy of sodium valproate and levetiracetam following initial lorazepam in elderly patients with generalized convulsive status epilepticus (GCSE): A prospective randomized controlled pilot study.

Seizure 2019 Feb 15;65:111-117. Epub 2019 Jan 15.

Department of Neurology, National Institute of Mental Health and NeuroSciences (NIMHANS), Bangalore, India. Electronic address:

Purpose: This randomized control study was conducted to compare the efficacy of sodium valproate (SVP) and levetiracetam (LEV) following initial intravenous lorazepam in elderly patients (age: >60years) with generalized convulsive status epilepticus (GCSE) and to identify predictors of poor seizure control.

Methods: A total of 118 patients (mean age: 67.5 ± 7. Read More

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http://dx.doi.org/10.1016/j.seizure.2019.01.015DOI Listing
February 2019
1 Read

Refractory status epilepticus during pregnancy resolved by cesarian section.

Seizure 2019 Feb 14;65:109-110. Epub 2019 Jan 14.

Marmara University School of Medicine, Department of Neurology, Istanbul, Turkey. Electronic address:

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http://dx.doi.org/10.1016/j.seizure.2019.01.012DOI Listing
February 2019
4 Reads

Progressive myoclonus epilepsy caused by a gain-of-function KCNA2 mutation.

Seizure 2019 Feb 8;65:106-108. Epub 2019 Jan 8.

Neurophysiopathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy; Department of Neurology, San Gerardo Hospital, School of Medicine and Surgery, Milan Center for Neuroscience (NeuroMi), University of Milano-Bicocca, Monza, Italy.

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http://dx.doi.org/10.1016/j.seizure.2019.01.005DOI Listing
February 2019
8 Reads

Patient management conference: Correlating pre-surgical data.

Seizure 2019 Jan 15. Epub 2019 Jan 15.

Cleveland Clinic Epilepsy Center, 9500 Euclid Avenue, Cleveland, OH 44195, United States. Electronic address:

The epilepsy surgery patient management conference is a fundamental part of the presurgical evaluation. This article reviews the literature and describes a single center's approach. Case examples highlight how patient management conferences may influence clinical care. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10591311183067
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http://dx.doi.org/10.1016/j.seizure.2019.01.006DOI Listing
January 2019
5 Reads

Managing epilepsy in austerity - Evaluating the utility and value of the epilepsy specialist nurse in an open access model of service delivery. Aneurin Bevan Epilepsy Specialist Team (A.B.E.S.T.).

Seizure 2019 Feb 11;65:98-100. Epub 2019 Jan 11.

Aneurin Bevan University Health Board, United Kingdom.

Purpose: Healthcare organisations in the UK primarily measure clinical activity from data collected on numbers of attendances at outpatient clinics, inpatient admissions and procedures performed etc. Telephone contacts with patients are not typically measured as clinical activity. This service evaluation examines the utility and value of the Epilepsy Specialist Nurse (ESN) within an innovative 'Open Access Model', giving a breakdown of clinical workload and outcomes. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10591311183081
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http://dx.doi.org/10.1016/j.seizure.2019.01.007DOI Listing
February 2019
5 Reads

Factors associated with the duration of the postictal state after a generalized convulsion.

Seizure 2019 Feb 2;65:101-105. Epub 2019 Jan 2.

Department of Neurology, Kobe City Medical Center General Hospital, 650-0047, 2-1-1 Minatojima-Minamimachi, Chuou-ku, Kobe, Hyogo, Japan.

Purpose: Few studies have assessed the duration of the postictal state after a generalized convulsion (GC) in adults. This study aimed to investigate the postictal duration after a GC and the factors associated with it.

Methods: Patients aged ≥16 years who presented to the emergency department of a community general hospital with an unprovoked GC from January 2015 through December 2016 were evaluated retrospectively. Read More

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http://dx.doi.org/10.1016/j.seizure.2019.01.001DOI Listing
February 2019
2 Reads

Reduced cerebrospinal fluid levels of interleukin-10 in children with febrile seizures.

Seizure 2019 Feb 14;65:94-97. Epub 2019 Jan 14.

Pediatric Emergency Unit, Department of Pediatrics, Okmeydani Training and Research Hospital, Istanbul, Turkey.

Purpose: The exact etiology of febrile seizures (FS) is still unclear. However, it is thought that cytokine network activation may have a causative role. Therefore, this study aimed to evaluate the levels of interleukin-12 (IL-12) as a proinflammatory cytokine, interleukin-10 (IL-10) as an anti-inflammatory cytokine, and interferon-β (IFN-β), a marker of toll-like receptor-3 activation as a host response to viruses. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10591311183061
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http://dx.doi.org/10.1016/j.seizure.2019.01.008DOI Listing
February 2019
6 Reads

Effects of antiepileptic drugs on dynamic thiol/disulphide homeostasis in children with idiopathic epilepsy.

Seizure 2019 Feb 26;65:89-93. Epub 2018 Dec 26.

Gazi University, Faculty of Medicine, Department of Pediatric Neurology, Turkey.

Purpose: Anti-epileptic drugs have been widely used in children with epilepsy. Although several studies have investigated the role of oxidative stress and the effects of antiepileptic drugs on several oxidative markers in epilepsy, adequate information is not available on this issue. This study aimed to investigate the changes in thiol disulphide homeostasis in children with epilepsy under two commonly prescribed AED monotherapies, carbamazepine and valproic acid. Read More

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http://dx.doi.org/10.1016/j.seizure.2018.12.019DOI Listing
February 2019
1 Read

Association between epilepsy and risk of sexual dysfunction: A meta-analysis.

Seizure 2019 Feb 10;65:80-88. Epub 2019 Jan 10.

Department of Urology & Andrology, Minimally Invasive Surgery Center, Guangdong Provincial Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510230, China. Electronic address:

Purpose: Sexual functioning is an important factor influencing quality of life. Mounting evidence suggests that both male and female patients with epilepsy (PWE) have an increased risk of developing sexual dysfunction (SD). The aim of this meta-analysis was to quantify the association between epilepsy and the risk of SD. Read More

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http://dx.doi.org/10.1016/j.seizure.2019.01.004DOI Listing
February 2019
1 Read

Caregiver impact and health service use in high and low severity Dravet syndrome: A multinational cohort study.

Seizure 2019 Feb 19;65:72-79. Epub 2018 Dec 19.

Wickenstones, Oxfordshire, United Kingdom. Electronic address:

Purpose: To estimate costs associated with the current management of Dravet syndrome (DS), explore psychosocial aspects of the disease in caregivers and siblings, and identify patient characteristics associated with higher costs in a large, predominantly European survey cohort of patients and their caregivers conducted in 2016.

Methods: Health and social care resource use, productivity and quality of life (QoL) data were summarised. Costs for European five (EU5) countries (France, Germany, Italy, Spain and UK) were calculated and patients with high and low current seizure burden compared. Read More

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http://dx.doi.org/10.1016/j.seizure.2018.12.018DOI Listing
February 2019
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Aberrant epileptic seizure identification: A computer vision perspective.

Seizure 2019 Feb 20;65:65-71. Epub 2018 Dec 20.

Department of Mater Advanced Epilepsy Unit, Mater Centre for Neurosciences, Brisbane, Australia.

Purpose: The recent explosion of artificial intelligence techniques in video analytics has highlighted the clinical relevance in capturing and quantifying semiology during epileptic seizures; however, we lack an automated anomaly identification system for aberrant behaviors. In this paper, we describe a novel system that is trained with known clinical manifestations from patients with mesial temporal and extra-temporal lobe epilepsy and presents aberrant semiology to physicians.

Methods: We propose a simple end-to-end-architecture based on convolutional and recurrent neural networks to extract spatiotemporal representations and to create motion capture libraries from 119 seizures of 28 patients. Read More

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http://dx.doi.org/10.1016/j.seizure.2018.12.017DOI Listing
February 2019
2 Reads

Early infantile SCN1A epileptic encephalopathy: Expanding the genotype-phenotype correlations.

Seizure 2019 Feb 2;65:62-64. Epub 2019 Jan 2.

Department of Pediatrics, Child Neurology Unit, AUSL-IRCCS di Reggio Emilia, Reggio Emilia, Italy; Pediatric Neurophysiology Laboratory, AUSL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.

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http://dx.doi.org/10.1016/j.seizure.2019.01.002DOI Listing
February 2019
1 Read

Factors predicting uncontrolled seizures in epilepsy with auditory features.

Seizure 2019 Feb 29;65:55-61. Epub 2018 Dec 29.

Department of Neurology, West China Hospital, Sichuan University, Chengdu, China. Electronic address:

Purpose: To analyse the factors predicting uncontrolled seizures in epilepsy with auditory features (EAF).

Methods: We analysed individual data from EAF patients who were previously reported. Two authors independently reviewed the titles and abstracts identified and extracted data from each eligible study using a standardized form. Read More

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http://dx.doi.org/10.1016/j.seizure.2018.12.023DOI Listing
February 2019
2 Reads

Tonic-clonic seizure detection using accelerometry-based wearable sensors: A prospective, video-EEG controlled study.

Seizure 2019 Feb 27;65:48-54. Epub 2018 Dec 27.

Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Neurology, Sahlgrenska University Hospital, Gothenburg, Sweden. Electronic address:

Purpose: The aim of this prospective, video-electroencephalography (video-EEG) controlled study was to evaluate the performance of an accelerometry-based wearable system to detect tonic-clonic seizures (TCSs) and to investigate the accuracy of different seizure detection algorithms using separate training and test data sets.

Methods: Seventy-five epilepsy surgery candidates undergoing video-EEG monitoring were included. The patients wore one three-axis accelerometer on each wrist during video-EEG. Read More

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http://dx.doi.org/10.1016/j.seizure.2018.12.024DOI Listing
February 2019
2 Reads

Oral health and dental status in people with epilepsy in rural China.

Seizure 2019 Feb 28;65:42-47. Epub 2018 Dec 28.

NIHR University College London Hospitals Biomedical Research Centre, UCL Queen Square Institute of Neurology, Queen Square, London, WC1N 3BG, United Kingdom; Chalfont Centre for Epilepsy, Chalfont St Peter, SL9 0RJ, United Kingdom; Stichting Epilepsie Instellingen Nederland (SEIN), Achterweg 5, Heemstede, 2103 SW, the Netherlands.

Purpose: We evaluated the oral health and dental status of people with epilepsy, and their relationship to seizure frequency, in a community cohort in rural China.

Methods: A cross-sectional study of people with epilepsy was carried out in areas in Henan, Shanxi and Ningxia provinces of China. All participants underwent a specially designed "Oral health and Dental status Questionnaire". Read More

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http://dx.doi.org/10.1016/j.seizure.2018.12.022DOI Listing
February 2019
7 Reads
2.059 Impact Factor

Perisylvian epileptic network revisited.

Seizure 2019 Feb 21;65:31-41. Epub 2018 Dec 21.

National Institute of Clinical Neuroscience, Budapest, Hungary.

We overview here the new data about the epileptic spectrum disorders within the frame of perisylvian epileptic network since our first trial to synthetize knowledge about this system epilepsy (Halász et al., 2005). We found evidences for a continual features relating together syndromes constituting this spectrum disorder in several fields: in sharing genetic origin, in common perisylvian human communication circuitry, in NREM sleep related potentiation of interictal epileptiform discharges of the centro-temporal spike phenomenon and in the discharge related cognitive impairment, reflecting functional deficits in human communication abilities. Read More

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http://dx.doi.org/10.1016/j.seizure.2018.12.003DOI Listing
February 2019
4 Reads

Association between HLA-A*3201 allele and oxcarbazepine-induced cutaneous adverse reactions in Eastern Han Chinese population.

Seizure 2019 Feb 18;65:25-30. Epub 2018 Dec 18.

Department of Neurology & Institute of Neurology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:

Purpose: To determine genetic associations between oxcarbazepine (OXC)-induced cutaneous adverse drug reactions (cADRs) and human leukocyte antigen (HLA) variants in the Eastern Han Chinese population.

Methods: A total of 120 patients were enrolled in this study, including 30 subjects with OXC-induced cADRs (case group) and 90 OXC-tolerant patients (control group). High-resolution HLA genotyping was conducted for HLA-A, HLA-B, HLA-C, and HLA-DRB1, and allele frequencies were compared. Read More

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http://dx.doi.org/10.1016/j.seizure.2018.12.011DOI Listing
February 2019
1 Read

EEG findings in NMDA encephalitis - A systematic review.

Seizure 2019 Feb 19;65:20-24. Epub 2018 Dec 19.

University of Queensland, Brisbane, Australia; Neurology Department, Princess Alexandra Hospital, Brisbane, Australia.

Purpose: The clinical utility of EEG in cases of NMDA encephalitis is broad with many findings indicating not just epileptiform activity but also encephalopathy and potentially providing insights into pathophysiologic mechanisms of disease. We aimed to determine the frequency of different abnormalities described on EEG and their association with outcome in patients affected by NMDARE through a systematic review of all cases published.

Method: A systematic literature review of PubMed and Embase of all published cases of anti-NMDA receptor encephalitis with EEG results, was performed from inception to January 2018. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10591311183065
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http://dx.doi.org/10.1016/j.seizure.2018.12.015DOI Listing
February 2019
6 Reads

Attitudes towards epilepsy in the UK population: Results from a 2018 national survey.

Seizure 2019 Feb 18;65:12-19. Epub 2018 Dec 18.

Centre for Health Economics and Medicines Evaluation (CHEME), Ardudwy, Bangor University, Normal Site, Gwynedd, Bangor, LL57 2PZ, United Kingdom.

Purpose: To measure stigma resulting from negative attitudes toward epilepsy in the United Kingdom (UK) population.

Methods: An online survey of a stratified quota sample of UK adults in July 2018. The primary outcome measure was the 46-item Attitudes and Beliefs about Living with Epilepsy (ABLE) scale, scored on a five-point Likert scale. Read More

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http://dx.doi.org/10.1016/j.seizure.2018.12.012DOI Listing
February 2019
1 Read

Recurrent seizure-triggered Takotsubo: A suggestive differential diagnosis.

Seizure 2019 Feb 19;65:177. Epub 2018 Dec 19.

Department of Cardiology, Azienda Ospedaliera Brotzu, Cagliari, Italy.

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http://dx.doi.org/10.1016/j.seizure.2018.12.014DOI Listing
February 2019
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Febrile seizures: Are they truly benign? Longitudinal analysis of risk factors and future risk of afebrile epileptic seizure based on the national sample cohort in South Korea, 2002-2013.

Seizure 2019 Jan 11;64:77-83. Epub 2018 Dec 11.

Department of Emergency Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.

Purpose: We performed a large, population-based study to analyze the risk factors of the febrile seizures and the subsequent afebrile epileptic seizures.

Methods: Relevant data from children born between 2002-2007 were retrieved from the Korean National Health Insurance Service-National Sample Cohort 2002-2013. Children who did not survive the first five years were excluded from the analysis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10591311183044
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http://dx.doi.org/10.1016/j.seizure.2018.12.004DOI Listing
January 2019
9 Reads

Antiepileptic drugs and foetal malformation: analysis of 20 years of data in a pregnancy register.

Seizure 2019 Feb 19;65:6-11. Epub 2018 Dec 19.

Royal Brisbane and Women's Hospital and School of Medicine and Biomedical Science, University of Queensland, Brisbane, Queensland, 4027 Australia.

Purpose: This paper reports additional data supplementing earlier publications based on Australian Pregnancy Register (APR) data.

Method: Over 20 years, the APR has collected Information on pregnancies in Australian women with epilepsy (WWE), untreated WWE and those taking AEDs for other indications. Contact is by telephone, at set intervals. Read More

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http://dx.doi.org/10.1016/j.seizure.2018.12.006DOI Listing
February 2019
2 Reads

Laser interstitial thermotherapy (LiTT) in pediatric epilepsy surgery.

Seizure 2018 Dec 18. Epub 2018 Dec 18.

Department of Epileptology, University of Bonn Medical Center, Sigmund-Freud-Strasse 25, 53127 Bonn, Germany.

Laser interstitial thermotherapy (LiTT) is a novel stereotactic approach to the surgical treatment of severe drug-resistant focal epilepsies. This review extends our recent general review on this topic (Hoppe et al. Laser interstitial thermotherapy [LiTT] in epilepsy surgery. Read More

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http://dx.doi.org/10.1016/j.seizure.2018.12.010DOI Listing
December 2018
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Value of combined video EEG and polysomnography in clinical management of children with epilepsy and daytime or nocturnal spells.

Seizure 2019 Feb 17;65:1-5. Epub 2018 Dec 17.

Dental School, Virginia Commonwealth University, United States.

Purpose: Sleep disorders are common in epilepsy. Additionally, events of staring, jerking, or nocturnal behaviors are common presentations in neurology or sleep practice. Moreover, sleepiness and nocturnal awakenings are common symptoms in children with epilepsy and differentiation form ongoing seizures and sleep disorders is needed. Read More

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http://dx.doi.org/10.1016/j.seizure.2018.12.009DOI Listing
February 2019
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Recurrent seizure-triggered Takotsubo associated with hypokalemia and hypomagnesemia.

Authors:
Josef Finsterer

Seizure 2019 Feb 4;65:176. Epub 2018 Dec 4.

Krankenanstalt Rudolfstiftung, Messerli Institute, Vterinary University of Vienna, Postfach 20, 1180, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.seizure.2018.12.001DOI Listing
February 2019
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Education in patients with psychogenic nonepileptic seizures.

Seizure 2019 Jan 14;64:74-76. Epub 2018 Dec 14.

Neuroscience Research Center, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:

Purpose: The aim of this study was to investigate any possible association between education and psychogenic nonepileptic seizures (PNES) and any potential effects education might have on clinical characteristics of patients with PNES.

Methods: In this retrospective study, all patients with PNES, who were studied at Shiraz Comprehensive Epilepsy Center at Shiraz University of Medical Sciences, from 2008 until 2018, were recruited. We categorized the patients as 1. Read More

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http://dx.doi.org/10.1016/j.seizure.2018.12.008DOI Listing
January 2019
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Sudden unexpected death in epilepsy: The neuro-cardio-respiratory connection.

Seizure 2019 Jan 13;64:65-73. Epub 2018 Dec 13.

Athens University School of Medicine, Athens, Greece. Electronic address:

Sudden unexpected death in epilepsy (SUDEP) is the major cause of epilepsy-related premature mortality which targets preferentially younger people. Its etiology remains unknown. Several risk factors have been identified with generalized tonic-clonic seizures as the most important one; seizure control remains the most effective measure of prevention. Read More

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http://dx.doi.org/10.1016/j.seizure.2018.12.007DOI Listing
January 2019
2 Reads

Seizures as a clinical manifestation in somatic autoimmune disorders.

Seizure 2019 Jan 5;64:59-64. Epub 2018 Dec 5.

Stichting Epilepsie Instellingen Nederland (SEIN), Achterweg 5, Heemstede, 2103SW, Netherlands; NIHR University College London Hospitals Biomedical Research Centre, UCL Queen Square Institute of Neurology, London, WC1N 3BG, United Kingdom; Chalfont Centre for Epilepsy, Chalfont St Peter, Bucks, SL9 0RJ, United Kingdom.

The risk of epileptic seizures seems increased in several systemic autoimmune disorders including systemic lupus erythematosus, type 1 diabetes mellitus, myasthenia gravis, celiac disease, rheumatoid arthritis, Hashimoto's encephalopathy, psoriasis, multiple sclerosis, neuromyelitis optica, and bullous pemphigoid. Immune dysfunction may be partly responsible for this association. Elevated levels of pro-inflammatory cytokines, autoantibodies seen in these autoimmune disorders and antibodies against neuronal antigens may contribute to the etiopathogenesis of seizures and epilepsy associated to immune conditions. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10591311183058
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http://dx.doi.org/10.1016/j.seizure.2018.11.012DOI Listing
January 2019
17 Reads
2.059 Impact Factor