850 results match your criteria Second-Degree Atrioventricular Block


Resolution of fetal second-degree atrioventricular block.

J Electrocardiol 2018 Nov - Dec;51(6):945-947. Epub 2018 Aug 17.

University of Massachusetts Medical School, Department of Pediatric Cardiology, 55 Lake Avenue North, Worcester, MA 01655, United States of America.

Fetal atrioventricular (AV) block is a rare and potentially devastating condition. Most commonly fetal AV block is mediated by maternal lupus antibodies which cause irreversible damage to the AV node. For many fetuses, the only potential intervention is premature delivery and highly invasive pacemaker implantation. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00220736183048
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http://dx.doi.org/10.1016/j.jelectrocard.2018.08.020DOI Listing
August 2018
5 Reads

Dysrhythmias in patients with a complete atrioventricular septal defect: From surgery to early adulthood.

Congenit Heart Dis 2018 Nov 28. Epub 2018 Nov 28.

Department of Cardiothoracic Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands.

Objective: Outcomes after surgical repair of complete atrioventricular septal defect (cAVSD) have improved. With advancing age, the risk of development of dysrhythmias may increase. The aims of this study were to (1) examine development of sinus node dysfunction (SND), atrial and ventricular tachyarrhythmias, and (2) study progression of atrioventricular conduction abnormalities in young adult patients with repaired cAVSD. Read More

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http://dx.doi.org/10.1111/chd.12724DOI Listing
November 2018
1 Read

A 48-Year-Old Athletic Man With Bradycardia During Sleep.

Chest 2018 Nov;154(5):e139-e142

Sleep Disorders Center, Neurologic Institute, Cleveland Clinic, Cleveland, OH.

Case Presentation: A 48-year-old athletic man with history of dyslipidemia and second-degree atrioventricular block (Mobitz type I 2:1 atrioventricular block) endorses sleep-related difficulties at his annual physical examination. Mobitz type I block was diagnosed 11 years earlier when the patient presented to his primary care physician with left-sided chest pain for 2 months. He was evaluated by cardiology, with a normal stress echocardiogram. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00123692183078
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http://dx.doi.org/10.1016/j.chest.2018.05.008DOI Listing
November 2018
5 Reads

Advanced Heart Block in Children with Lyme Disease.

Pediatr Cardiol 2018 Oct 31. Epub 2018 Oct 31.

Department of Pediatrics, Division of Pediatric Cardiology, Columbia University, College of Physicians and Surgeons, 3959 Broadway, 2-North, New York, NY, USA.

Background: The clinical course of children with advanced heart block secondary to Lyme disease has not been well characterized.

Objective: To review the presentation, management, and time to resolution of heart block due to Lyme disease in previously healthy children.

Methods: An IRB approved single-center retrospective study was conducted of all patients < 21 years old with confirmed Lyme disease and advanced second or third degree heart block between 2007 and 2017. Read More

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http://dx.doi.org/10.1007/s00246-018-2003-8DOI Listing
October 2018
3 Reads

Outcome of Cardiac Sarcoidosis Presenting With High-Grade Atrioventricular Block.

Circ Arrhythm Electrophysiol 2018 Aug;11(8):e006145

Heart and Lung Center (H.-K.N., J.L., K.E., R.K., P.S., M.K.).

Background: Symptomatic high-grade atrioventricular block (AVB) is the most common and often the only presenting manifestation (lone AVB) of cardiac sarcoidosis. Implantation of an intracardiac cardioverter defibrillator instead of a pacemaker is recommended, but the true risk of fatal arrhythmia, one incident to lone AVB in particular, remains poorly known.

Methods: We used Myocardial Inflammatory Diseases in Finland Study Group Registry to analyze the presentations, left ventricular (LV) function, pacemaker therapy, and ventricular arrhythmias in cardiac sarcoidosis. Read More

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https://www.ahajournals.org/doi/10.1161/CIRCEP.117.006145
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http://dx.doi.org/10.1161/CIRCEP.117.006145DOI Listing
August 2018
6 Reads

The Incremental Benefit of Color Tissue Doppler in Fetal Arrhythmia Assessment.

J Am Soc Echocardiogr 2019 Jan 16;32(1):145-156. Epub 2018 Oct 16.

Fetal and Neonatal Cardiology Program, Department of Pediatrics, Division of Cardiology, Women's & Children's Health Research Institute, University of Alberta, Stollery Children's Hospital, Edmonton, Alberta, Canada. Electronic address:

Background: Accurate fetal arrhythmia (FA) diagnosis is key for effective management. Currently, FA assessment relies on standard echocardiography-based techniques (M mode and spectral Doppler), which require adequate fetal position and cursor alignment to define temporal relationships of mechanical events. Few data exist on the application of color Doppler tissue imaging (c-DTI) in FA assessment. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08947317183044
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http://dx.doi.org/10.1016/j.echo.2018.08.009DOI Listing
January 2019
9 Reads

Home Monitoring for Fetal Heart Rhythm During Anti-Ro Pregnancies.

J Am Coll Cardiol 2018 Oct;72(16):1940-1951

Division of Cardiology, Department of Pediatrics, Hospital for Sick Children, Toronto, Canada.

Background: Fetal atrioventricular block (AVB) occurs in 2% to 4% of anti-Ro antibody-positive pregnancies and can develop in <24 h. Only rarely has standard fetal heart rate surveillance detected AVB in time for effective treatment.

Objectives: Outcome of anti-Ro pregnancies was surveilled with twice-daily home fetal heart rate and rhythm monitoring (FHRM) and surveillance echocardiography. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07351097183694
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http://dx.doi.org/10.1016/j.jacc.2018.07.076DOI Listing
October 2018
18 Reads

Coma, Seizures, Atrioventricular Block, and Hypoglycemia in an ADB-FUBINACA Body-Packer.

J Emerg Med 2018 Dec 5;55(6):788-791. Epub 2018 Oct 5.

Department of Emergency Medicine, University of Rochester Medical Center, Rochester, New York; Upstate Poison Center, Syracuse, New York.

Background: Synthetic cannabinoid intoxication has become difficult to diagnose and manage in the United States, in part due to varying clinical effects within this heterogeneous group of compounds.

Case Report: A 38-year-old man was admitted with altered mental status and bradycardia. He demonstrated progressive encephalopathy, seizure activity, second-degree atrioventricular block type I, respiratory failure, hypotension, hypothermia, and hypoglycemia. Read More

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http://dx.doi.org/10.1016/j.jemermed.2018.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289710PMC
December 2018
9 Reads

A Rare Case of Second Degree Mobitz Type II AV Block Associated with Cocaine Use.

Am J Med Case Rep 2018 21;6(7):146-148. Epub 2018 Aug 21.

Department of Internal Medicine, State University of New York Downstate Medical Center, Brooklyn, New York, U.S.A- 11203.

Cocaine is a commonly abused illicit drug in the United States. The complex effects of cocaine on the conduction system of the human heart has not been completely understood. Cocaine acts as a sympathomimetic by inhibition of reuptake of neuronal catecholamines, leading mostly to tachyarrhythmias on presentation. Read More

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http://pubs.sciepub.com/ajmcr/6/7/7/index.html
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http://dx.doi.org/10.12691/ajmcr-6-7-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173318PMC
August 2018
2 Reads

Characterization of Australian Labradoodle dystrophinopathy.

Neuromuscul Disord 2018 Nov 29;28(11):927-937. Epub 2018 Aug 29.

Department of Pathobiology, Auburn University College of Veterinary Medicine, Auburn, AL 36849, USA; Scott-Ritchey Research Center, Auburn University College of Veterinary Medicine, Auburn, AL 36849, USA.

In humans, dystrophin mutations cause the X-linked recessive disorder known as Duchenne muscular dystrophy (DMD). These mutations result in skeletal and cardiac muscle damage with mortality increasingly associated with cardiomyopathy. We have identified a novel dystrophin mutation in exon 21 in a line of Australian Labradoodles; affected dogs develop progressive clinical signs including poor weight gain and weight loss, gait abnormalities, exercise intolerance, skeletal muscle atrophy, macroglossa, ptyalism, dysphagia, kyphosis, and a plantigrade stance. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09608966183012
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http://dx.doi.org/10.1016/j.nmd.2018.08.008DOI Listing
November 2018
3 Reads

Dynamic Electrocardiography is Useful in the Diagnosis of Persistent Atrial Fibrillation Accompanied with Second-Degree Atrioventricular Block.

Acta Cardiol Sin 2018 Sep;34(5):409-416

Department of Cardiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China.

Background: Periodic electrocardiography (ECG) at every clinical visit is generally performed for heart rhythm surveillance, and 24-h Holter ECG is usually used as the gold standard. We aimed to investigate the electrocardiographic features of persistent atrial fibrillation (AF) accompanied with second-degree atrioventricular block (AVB).

Methods: From October 2012 to November 2015, 204 patients with an RR interval > 2. Read More

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http://dx.doi.org/10.6515/ACS.201809_34(5).20180326EDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160510PMC
September 2018
2 Reads
0.840 Impact Factor

Frequency and Significance of High-Degree Atrioventricular Block and Sinoatrial Node Dysfunction in Patients With Non-ST-Elevation Myocardial Infarction.

Am J Cardiol 2018 Nov 21;122(10):1598-1603. Epub 2018 Aug 21.

Division of Cardiovascular Medicine, Gill Heart Institute, University of Kentucky, Lexington, KY and VA Medical Center, Lexington, Kentucky.

Characteristics of conduction disorders after ST-elevation myocardial infarction (STEMI) have been well described. In contrast, limited data are available on the incidence, treatment trends, and prognostic impact of conduction disorders after non-ST-elevation myocardial infarction (NSTEMI). Using the National Inpatient Sample database, we compared the characteristics and outcomes of conduction disorders in patients with a primary diagnosis of STEMI versus NSTEMI between 2010 and 2014. Read More

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http://dx.doi.org/10.1016/j.amjcard.2018.08.001DOI Listing
November 2018
2 Reads

A new and simple technique for vagal ganglia ablation in a patient with functional atrioventricular block: Electroanatomical approach.

Turk Kardiyol Dern Ars 2018 09;46(6):494-500

Department of Cardiology, University of Health Sciences, Kocaeli Derince Training and Research Hospital, Kocaeli, Turkey.

Increased parasympathetic tone may cause symptomatic functional atrioventricular block (AVB) and necessitate pacemaker implantation. In these patients, where there is no structural damage to the conduction system, removal of the vagal activity using radiofrequency ablation seems to be a theoretically rational approach. Several methods have been used to determine suitable areas for vagal ganglia ablation. Read More

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http://dx.doi.org/10.5543/tkda.2017.15163DOI Listing
September 2018
1 Read

Association between decreasing estimated glomerular filtration rate and risk of cardiac conduction defects in patients with type 2 diabetes.

Diabetes Metab 2018 12 5;44(6):473-481. Epub 2018 Sep 5.

Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Piazzale Stefani, 1, 37126 Verona, Italy. Electronic address:

Aim: We aimed to assess the association between decreasing estimated glomerular filtration rate (eGFR) or abnormal albuminuria and the risk of certain cardiac conduction defects in patients with type 2 diabetes mellitus (T2DM).

Methods: We examined a hospital-based sample of 923 patients with T2DM discharged from our Division of Endocrinology over the years 2007-2014. Standard electrocardiograms (ECGs) were performed in all patients. Read More

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http://dx.doi.org/10.1016/j.diabet.2018.08.007DOI Listing
December 2018
2 Reads

Short-Duration AL-335, Odalasvir, With or Without Simeprevir, in Patients With HCV GT1 or 3 Infection Without Cirrhosis.

Hepatology 2018 Dec 19;68(6):2145-2157. Epub 2018 Nov 19.

Alios BioPharma Inc. part of the Janssen Pharmaceutical Companies, South San Francisco, California.

This open-label, phase IIa study assessed the safety, pharmacokinetics, and efficacy of direct-acting antiviral agent (DAA) regimens in patients with chronic hepatitis C virus (HCV) infection. Multiple 6-12-week oral regimens of 400-800 mg once daily (QD) AL-335 + 50 mg QD/every other day odalasvir ± 75-150 mg QD simeprevir were evaluated in treatment-naïve, HCV genotype (GT)1/3-infected patients without cirrhosis. Safety/pharmacokinetic parameters, HCV-RNA, and sequencing data were assessed. Read More

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http://dx.doi.org/10.1002/hep.30126DOI Listing
December 2018
3 Reads

Type I Second Degree Atrioventricular Block in a Woman With Remote Repair of a Ventricular Septal Defect.

Am J Cardiol 2018 Sep 23;122(6):1111-1112. Epub 2018 Jun 23.

Section of Cardiology, Department of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana. Electronic address:

In a 45-year-old woman with syncope, an electrocardiogram revealed intermittent asymptomatic type I second degree atrioventricular block, right bundle branch block and left anterior fascicular block. An echocardiogram documented concentric left ventricular hypertrophy and right ventricular dilatation and hypokinesia. Because the patient did not have second degree atrioventricular block at the time of an electrophysiological study, the atrioventricular node, the left posterior fascicle, and the His bundle all remain potential sites for the type I second degree atrioventricular block on her initial electrocardiogram. Read More

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http://dx.doi.org/10.1016/j.amjcard.2018.05.041DOI Listing
September 2018
2 Reads
3.280 Impact Factor

Efficacy and safety of ozanimod in multiple sclerosis: Dose-blinded extension of a randomized phase II study.

Mult Scler 2018 Jul 25:1352458518789884. Epub 2018 Jul 25.

Neurologic Clinic and Polyclinic, University Hospital of Basel and University of Basel, Basel, Switzerland.

Background: Ozanimod, an oral immunomodulator, selectively targets sphingosine 1-phosphate receptors 1 and 5.

Objective: Evaluate efficacy, safety, and tolerability of ozanimod in relapsing multiple sclerosis.

Methods: In the RADIANCE Part A phase II study (NCT01628393), participants with relapsing multiple sclerosis were randomized (1:1:1) to once-daily ozanimod hydrochloride (0. Read More

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http://dx.doi.org/10.1177/1352458518789884DOI Listing
July 2018
29 Reads

Lyme Carditis: A Case Report and Review of Management.

Hosp Pharm 2018 Jul 2;53(4):263-265. Epub 2018 Jan 2.

University of Pittsburgh Medical Center Mercy, PA, USA.

A case report of a patient who presented with an acute onset, fluctuating atrioventricular (AV) block and was diagnosed with Lyme carditis is presented. A 55-year-old man with progressively worsening generalized malaise, flu-like symptoms, dyspnea on exertion, and near syncope was admitted with bradycardia (heart rate was between 20 and 30 beats per minute upon admission). He endorsed having several tick bites after which he developed erythema migrans on his arm and abdomen. Read More

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http://dx.doi.org/10.1177/0018578717749927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050884PMC
July 2018
1 Read

A Case of Atrioventricular Block Potentially Associated with Right Coronary Artery Lesion and Ticagrelor Therapy Mediated by the Increasing Adenosine Plasma Concentration.

Case Rep Vasc Med 2018 19;2018:9385017. Epub 2018 Apr 19.

Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.

Purpose: To report a case of atrioventricular block (AVB) which might be associated with the right coronary artery lesion and the novel oral antithrombotic drug ticagrelor mediated by the increasing adenosine plasma concentration (APC).

Case Report: A 65-year-old man was given loading dose of ticagrelor (180 mg) before coronary angiography with total thrombotic occlusion of right coronary artery and one stent was implanted. On second day after successful percutaneous coronary intervention, ECG monitoring showed second-degree (Mobitz type I) AVB with prolonged PR interval (299 ms). Read More

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http://dx.doi.org/10.1155/2018/9385017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933017PMC
April 2018
1 Read

Safety, tolerability, pharmacokinetics, and pharmacodynamics of GLPG1690, a novel autotaxin inhibitor, to treat idiopathic pulmonary fibrosis (FLORA): a phase 2a randomised placebo-controlled trial.

Lancet Respir Med 2018 Aug 20;6(8):627-635. Epub 2018 May 20.

Unit for Interstitial Lung Diseases, Department of Pulmonary Medicine, University Hospitals Leuven, Leuven, Belgium.

Background: Idiopathic pulmonary fibrosis (IPF) causes irreversible loss of lung function. People with IPF have increased concentrations of autotaxin in lung tissue and lysophosphatidic acid (LPA) in bronchoalveolar lavage fluid and exhaled condensate. GLPG1690 (Galapagos, Mechelen, Belgium) is a novel, potent, selective autotaxin inhibitor with good oral exposure. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22132600183018
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http://dx.doi.org/10.1016/S2213-2600(18)30181-4DOI Listing
August 2018
26 Reads

Acute Pediatric Colchicine Toxicity is Associated with Marked Bradydysrhythmias.

J Emerg Med 2018 09 29;55(3):e65-e69. Epub 2018 May 29.

Division of Cardiology, Department of Pediatrics, Rush University Medical College, Chicago, Illinois.

Background: Colchicine ingestion is rare but highly lethal. Patients usually die of multiorgan failure and cardiogenic shock. Colchicine is not only associated with depressed myocardial function but also with fatal heart rhythm disturbances, such as complete heart block, ventricular tachycardia, and asystole. Read More

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http://dx.doi.org/10.1016/j.jemermed.2018.03.004DOI Listing
September 2018
2 Reads

Clinical and electrocardiographic presentations of transient trifascicular block in three cats.

J Vet Cardiol 2018 Jun 20;20(3):204-212. Epub 2018 Mar 20.

Cornell University College of Veterinary Medicine, 930 Campus Road, 14853, Ithaca, NY, USA. Electronic address:

This report describes transient trifascicular block in three cats presented with lethargy and inappetence, and elevated cardiac troponin I concentrations. The electrocardiogram (ECG) of cat 1 showed a sinus rhythm with pronounced first-degree atrioventricular (AV) block, right bundle branch block, and left anterior fascicular block. The ECG of cat 2 showed truncular left bundle branch block alternating with left anterior fascicular block coupled with prolonged PR intervals, second-degree heart block, and paroxysmal third-degree AV block. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17602734173020
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http://dx.doi.org/10.1016/j.jvc.2018.02.002DOI Listing
June 2018
6 Reads

Beer, hyponatraemia and cardiac conduction defects.

BMJ Case Rep 2018 Mar 14;2018. Epub 2018 Mar 14.

Department of Medicine, Mater Dei Hospital, Msida, Malta.

The authors report a case of a 68-year-old man who was diagnosed with an irreversible second-degree atrioventricular (AV) Mobitz II 2:1 block temporally associated with profound hyponatraemia. The cause of the hyponatraemia was beer potomania. The co-occurrence of reversible first, second and third-degree heart blocks and hyponatraemia has been described in a few published case reports. Read More

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http://dx.doi.org/10.1136/bcr-2018-224260DOI Listing
March 2018
4 Reads

Incidence of arrhythmias and impact of permanent pacemaker implantation in hospitalizations with transcatheter aortic valve replacement.

Clin Cardiol 2018 May 10;41(5):640-645. Epub 2018 May 10.

Department of Cardiology, North Shore University Hospital, Northwell Health, Manhasset, New York.

Background: This study sought to analyze in-hospital outcomes associated with preexisting and newly implanted permanent pacemaker (PPM) in patients who underwent transcatheter aortic valve replacement (TAVR). PPM implantation following the development of conduction abnormalities is a common adverse event following TAVR. Furthermore, PPM implantation rates are higher in TAVR hospitalizations compared with the surgical alternative, thus we have analyzed the predictors of pacing post-TAVR. Read More

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http://dx.doi.org/10.1002/clc.22943DOI Listing
May 2018
3 Reads

Maternal steroid therapy for fetuses with second-degree immune-mediated congenital atrioventricular block: a systematic review and meta-analysis.

Acta Obstet Gynecol Scand 2018 Jul 18;97(7):787-794. Epub 2018 Apr 18.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA, USA.

Introduction: The aim of this study was to explore the effect of maternal fluorinated steroid therapy on fetuses affected by second-degree immune-mediated congenital atrioventricular block.

Material And Methods: Studies reporting the outcome of fetuses with second-degree immune-mediated congenital atrioventricular block diagnosed on prenatal ultrasound and treated with fluorinated steroids compared with those not treated were included. The primary outcome was the overall progression of congenital atrioventricular block to either continuous or intermittent third-degree congenital atrioventricular block at birth. Read More

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http://dx.doi.org/10.1111/aogs.13338DOI Listing
July 2018
16 Reads
1.990 Impact Factor

Type I Wenckebach second-degree AV block: A matter of definition.

Authors:
S Serge Barold

Clin Cardiol 2018 03 20;41(3):282-284. Epub 2018 Feb 20.

Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York.

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http://dx.doi.org/10.1002/clc.22874DOI Listing
March 2018
1 Read

General anesthesia in a patient with asymptomatic second-degree two-to-one atrioventricular block.

JA Clin Rep 2017 10;3(1):27. Epub 2017 May 10.

Department of Anesthesiology and Intensive Care Medicine, Kochi Medical School, Kohasu, Oko-cho, Nankoku, Kochi 783-8505 Japan.

Background: The major perioperative concern in patients with second-degree atrioventricular (AV) block is the progression to complete AV block. Therefore, the prophylactic implantation of a temporary pacemaker prior to surgery is recommended, especially in symptomatic patients. However, as no quantitative preoperative risk assessment from progression to complete AV block is available, there is currently no established indication for preoperative prophylactic pacemaker implantation. Read More

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http://dx.doi.org/10.1186/s40981-017-0099-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804611PMC
May 2017
3 Reads

Hisian extrasystole mimicking second degree atrioventricular block. a case report.

Tunis Med 2017 Feb;95(2):145-148

Hisian extrasystoles originate from the His bundle. They are rare and usually misdiagnosed. In fact, they manifest on the EKG, with a p' wave located before, in or after the QRS complex. Read More

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February 2017
4 Reads

Implantable loop recorders in patients with unexplained syncope:Clinical predictors of pacemaker implantation.

Cardiol J 2018 Feb 5. Epub 2018 Feb 5.

Department of Cardiology, Charité - Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany, Germany.

Background: Implantable loop recorders (ILR) are a valuable tool for the investigation of unexplained syncopal episodes. The aim of this retrospective single center study was to identify predictive factors for pacemaker implantation in patients with unexplained syncope who underwent ILR insertion.

Methods: 106 patients were retrospectively analyzed (mean age 59. Read More

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http://dx.doi.org/10.5603/CJ.a2018.0008DOI Listing
February 2018
3 Reads

The analysis of the parameters of 24-hr ECG Holter monitoring in patients with blood neoplasms undergoing high-dose chemotherapy and stem cell transplantation.

Ann Noninvasive Electrocardiol 2018 Jul 24;23(4):e12534. Epub 2018 Jan 24.

Department of Internal Medicine, Occupational Diseases and Hypertension, Wroclaw Medical University, Wroclaw, Poland.

Background: Hematopoietic stem cell transplantation (HSCT) is a widely used procedure in the treatment of malignant diseases, including blood neoplasms and has increased survival in hematological diseases. The aim of the study was to analyze parameters of 24-hr ECG monitoring in patients with selected blood neoplasms in whom the procedure of hematopoietic stem cell transplantation was performed.

Methods: The study group consisted of 64 adults diagnosed with hematologic cancer qualified for HSCT with the previous high dose chemotherapy (HDC). Read More

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http://doi.wiley.com/10.1111/anec.12534
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http://dx.doi.org/10.1111/anec.12534DOI Listing
July 2018
9 Reads

Lyme carditis: Early occurrence and prolonged recovery.

J Electrocardiol 2018 May - Jun;51(3):516-518. Epub 2017 Dec 14.

Department of Medicine, Division of Cardiology, Suny Upstate University Hospital, Syracuse, NY, USA.

Lyme carditis is an uncommon manifestation of early disseminated Lyme disease. This case illustrates a 66-year-old male with complaints of fatigue, myalgias, and fever after a tick bite 3days earlier. A large erythema migrans was found on the chest wall. Read More

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http://dx.doi.org/10.1016/j.jelectrocard.2017.12.035DOI Listing
December 2017
8 Reads

Prenatal sonographic monitoring of progressive cardiac damages caused by anti-Ro antibodies: A case report.

J Clin Ultrasound 2018 Jun 12;46(5):347-350. Epub 2017 Oct 12.

Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Thailand.

Maternal autoantibodies to Ro/SSA are often linked to congenital heart block and rarely associated with structural defects. We describe the case of a fetus with anti-Ro-mediated second-degree block at 19 weeks, which progressed to a complete block, fibroelastosis, atrioventricular valve insufficiency, and semilunar valve stenosis/insufficiency at 20, 22, 24, and 26 weeks, respectively, although the fetus received transplacental anti-arrhythmic drugs. The 2150-g fetus was vaginally delivered at 35 weeks. Read More

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http://dx.doi.org/10.1002/jcu.22541DOI Listing
June 2018
20 Reads

A second-degree atrioventricular block with double escape rhythm secondary to paroxysmal vagal hypertonia.

J Cardiovasc Med (Hagerstown) 2017 10;18(10):822-823

aU.O.C. Medicina Vascolare bDipartimento Biomedico di Medicina Interna e Specialistica, U.O.C. Medicina Interna e Cardioangiologia. , Università degli Studi di Palermo, Palermo, Italy.

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http://dx.doi.org/10.2459/JCM.0b013e3283641e37DOI Listing
October 2017
17 Reads

Catheter ablation as a treatment of atrioventricular block.

Heart Rhythm 2018 01 18;15(1):90-96. Epub 2017 Aug 18.

Section of Cardiac Electrophysiology and Pacing, Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio. Electronic address:

Background: Symptomatic second-degree atrioventricular (AV) block is typically treated by implantation of a pacemaker. An otherwise healthy AV conduction system can nevertheless develop AV block due to interference from junctional extrasystoles. When present with a high burden, these can produce debilitating symptoms from AV block despite an underlying normal AV node and His-Purkinje system properties. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15475271173099
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http://dx.doi.org/10.1016/j.hrthm.2017.08.015DOI Listing
January 2018
7 Reads

The use of non-invasive fetal electrocardiography in diagnosing second-degree fetal atrioventricular block.

Matern Health Neonatol Perinatol 2017 3;3:14. Epub 2017 Aug 3.

Institute of Biomedical Engineering, University of Oxford, Oxford, UK.

Background: Complete atrioventricular block in fetuses is known to be mostly associated with autoimmune disease and can be irreversible if no steroids treatment is provided. Conventional methods used in clinical practice for diagnosing fetal arrhythmia are limited since they do not reflect the primary electrophysiological conduction processes that take place in the myocardium. The non-invasive fetal electrocardiogram has the potential to better support fetal arrhythmias diagnosis through the continuous analysis of the beat to beat variation of the fetal heart rate and morphological analysis of the PQRST complex. Read More

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http://dx.doi.org/10.1186/s40748-017-0053-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541729PMC
August 2017
28 Reads

Conduction disturbance after isolated surgical aortic valve replacement in degenerative aortic stenosis.

J Thorac Cardiovasc Surg 2017 Nov 15;154(5):1556-1565.e1. Epub 2017 Jun 15.

Department of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Objective: Conduction disturbances are common in patients with aortic stenosis. We investigated the incidence, reversibility, and prognosis of conduction disorders requiring permanent pacemaker implantation in patients with degenerative aortic stenosis after isolated aortic valve replacement.

Methods: This was a retrospective study conducted at a tertiary care center. Read More

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http://dx.doi.org/10.1016/j.jtcvs.2017.05.101DOI Listing
November 2017
22 Reads

[Sudden cardiac death due to sarcoidosis. Case report].

Orv Hetil 2017 Jul;158(27):1067-1070

Patológiai Osztály, Bács-Kiskun Megyei Kórház Kecskemét, Nyíri út 38., 6000.

Sarcoidosis is a systemic granulomatous disease of unknown aetiology, which is characterized by bilateral hilar lymphadenopathy and pulmonary disease. Clinically detected cardiac involvement occurs in 5% of sarcoid patients, although cardiac manifestations are discovered in 25% of the cases at autopsy. Sarcoid heart disease frequently causes atrioventricular block. Read More

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http://dx.doi.org/10.1556/650.2017.30724DOI Listing
July 2017
26 Reads

Successful prenatal management of ventricular tachycardia and second-degree atrioventricular block in fetal long QT syndrome.

HeartRhythm Case Rep 2017 Jan 21;3(1):53-57. Epub 2016 Sep 21.

Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center, Osaka, Japan.

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http://dx.doi.org/10.1016/j.hrcr.2016.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420015PMC
January 2017
16 Reads

Diagnostic value of prehospital ECG in acute stroke patients.

Neurology 2017 May 21;88(20):1894-1898. Epub 2017 Apr 21.

From the Departments of Neurology (T.B., B.K., M. Kopp, N.K., S.H., S.S., M. Köhrmann) and Cardiology (M.A.), Universitätsklinikum Erlangen; and Department of Neurology (M. Köhrmann), Universitätsklinikum Essen, Germany.

Objective: To investigate the diagnostic yield of prehospital ECG monitoring provided by emergency medical services in the case of suspected stroke.

Methods: Consecutive patients with acute stroke admitted to our tertiary stroke center via emergency medical services and with available prehospital ECG were prospectively included during a 12-month study period. We assessed prehospital ECG recordings and compared the results to regular 12-lead ECG on admission and after continuous ECG monitoring at the stroke unit. Read More

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http://dx.doi.org/10.1212/WNL.0000000000003940DOI Listing
May 2017
7 Reads

Ivabradine vs metoprolol in patients with acute inferior wall myocardial infarction-"Expanding arena for ivabradine".

Cardiovasc Ther 2017 Aug;35(4)

Escorts Heart Hospital, New Delhi, India.

Background: Atrioventricular (AV) blocks are of concern with the use of beta blockers in inferior wall myocardial infarction (MI). Ivabradine lowers heart rate with a lesser risk of AV blocks.

Objectives: To compare ivabradine with metoprolol in acute inferior wall MI in terms of feasibility, tolerability, and efficacy. Read More

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http://dx.doi.org/10.1111/1755-5922.12266DOI Listing
August 2017
12 Reads

Heart rate variability parameters in horses distinguish atrial fibrillation from sinus rhythm before and after successful electrical cardioversion.

Equine Vet J 2017 Nov 24;49(6):723-728. Epub 2017 Apr 24.

Department of Large Animal Internal Medicine, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.

Background: Atrial fibrillation (AF) is the most common pathological arrhythmia in horses. After successful treatment, recurrence is common. Heart rate monitors are easily applicable in horses and some devices offer basic heart rate variability (HRV) calculations. Read More

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http://dx.doi.org/10.1111/evj.12684DOI Listing
November 2017
14 Reads

Incidence, Predictors, and Outcomes of High-Grade Atrioventricular Block in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention (from the HORIZONS-AMI Trial).

Am J Cardiol 2017 05 16;119(9):1295-1301. Epub 2017 Feb 16.

Cardiovascular Research Foundation, Clinical Trials Center, New York, New York; Department of Cardiology, NewYork-Presbyterian Hospital, Columbia University Medical Center, New York, New York.

High-grade atrioventricular block (HAVB) is historically considered a marker of worse outcomes in patients with ST-segment elevation myocardial infarction (STEMI). However, the predictors and prognostic impact of HAVB in the primary percutaneous coronary intervention (PCI) era remain poorly understood. We sought to describe the characteristics and predictors of HAVB in patients undergoing primary PCI in STEMI and to assess the prognostic significance of HAVB in the contemporary reperfusion era. Read More

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http://dx.doi.org/10.1016/j.amjcard.2017.01.019DOI Listing
May 2017
27 Reads

Obstetric and perinatal outcome in anti-Ro/SSA-positive pregnant women: a prospective cohort study.

Immunol Res 2017 04;65(2):487-494

Obstetric and Gynecology Department, High Risk Pregnancy Unit, Autoimmune diseases and pregnancy clinic, University Hospital La Paz, Paseo de la Castella 261, 28046, Madrid, Spain.

Anti-Ro/SS-A is one specific type of antinuclear antibodies. They are in the majority of cases associated with primary Sjögren syndrome (SS) but also in Systemic Lupus Erythematosus (SLE), rheumatoid arthritis (RA), and in healthy people. During pregnancy, they are mainly associated to congenital heart block (CHB) and neonatal lupus (NL). Read More

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http://dx.doi.org/10.1007/s12026-016-8888-5DOI Listing
April 2017
47 Reads

Electrocardiographic assessments and cardiac events after fingolimod first dose - a comprehensive monitoring study.

BMC Neurol 2017 Jan 18;17(1):11. Epub 2017 Jan 18.

Charité Universitaetsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, Berlin, 13353, Germany.

Background: First dose observation for cardiac effects is required for fingolimod, but recommendations on the extent vary. This study aims to assess cardiac safety of fingolimod first dose. Individual bradyarrhythmic episodes were evaluated to assess the relevance of continuous electrocardiogram (ECG) monitoring. Read More

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http://dx.doi.org/10.1186/s12883-016-0789-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241949PMC
January 2017
40 Reads

Permanent pacemaker implantation in octogenarians with unexplained syncope and positive electrophysiologic testing.

Heart Rhythm 2017 05 12;14(5):694-699. Epub 2017 Jan 12.

2nd Department of Cardiology, National and Kapodistrean University of Athens Medical School, Attikon University Hospital, Athens, Greece.

Background: Syncope is a common problem in the elderly, and a permanent pacemaker is a therapeutic option when a bradycardic etiology is revealed. However, the benefit of pacing when no association of symptoms to bradycardia has been shown is not clear, especially in the elderly.

Objective: The aim of this study was to evaluate the effect of pacing on syncope-free mortality in patients aged 80 years or older with unexplained syncope and "positive" invasive electrophysiologic testing (EPT). Read More

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http://dx.doi.org/10.1016/j.hrthm.2017.01.012DOI Listing
May 2017
9 Reads

Effects of reduced food intake for 4 weeks on physiological parameters in toxicity studies in dogs.

J Toxicol Sci 2017 ;42(1):31-42

Drug Safety, Drug Safety and Pharmacokinetics Laboratories, Taisho Pharmaceutical Co., Ltd.

This study sought to clarify the effects of reduced feeding on physiological parameters in dogs to enable appropriate evaluations of the safety and toxicity of test compounds. We measured alkaline phosphatase isozymes and the circulating blood volume, as well as clinical signs, body weight, hematology, blood chemistry, electrocardiography, organ weight, and histopathology, in male beagle dogs fed a diet consisting of 300 g/day or 150 g/day for 4 weeks. There were no abnormal clinical signs in any of the dogs. Read More

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http://dx.doi.org/10.2131/jts.42.31DOI Listing
May 2017
7 Reads