Am J Surg Pathol 2021 Feb 24. Epub 2021 Feb 24.
*CARADERM, French Network of Rare Cutaneous Cancer †Department of Pathology, Timone University Hospital ‡Aix Marseille University, INSERM, MMG, Marseille §Department of Pathology, Trousseau University Hospital, Tours ∥Department of Pathology, Cochin Hospital, AP-HP Paris University Center ¶University of Paris #Molecular Oncology Unit ∥∥Department of Pathology, Hospital Saint-Louis, AP-HP **INSERM, U976 HIPI, Paris ††Department of Dermatology, Lyon-Sud Hospital ‡‡Department of Biopathology, Léon Bérard Centre, Cypath, Lyon §§Department of Pathology, Bordeaux University Hospitals, Pessac ¶¶Department of Pathology, University Hospital of Poitiers ##LITEC EA 4331, B36, Poitiers, France.
YAP1-NUTM1 fusion transcripts have been recently reported in poroma and porocarcinoma. NUTM1 translocation can be screened by nuclear protein in testis (NUT) immunohistochemistry in various malignancies, but its diagnostic performance has not been thoroughly validated on a large cohort of cutaneous epithelial neoplasms. We have evaluated NUT immunohistochemical expression in a large cohort encompassing 835 cases of various cutaneous epidermal or adnexal epithelial neoplasms. Read More