3,534 results match your criteria Seborrheic Dermatitis

Chronic itch in African Americans: an unmet need.

Arch Dermatol Res 2021 Jun 15. Epub 2021 Jun 15.

Dr. Phillip Frost Department of Dermatology and Miami Itch Center, University of Miami, Miami, FL, USA.

Chronic pruritus carries a significant burden of disease and is associated with a negative impact on quality of life. African Americans are disproportionately burdened by chronic pruritic disorders, including but not limited to atopic dermatitis, prurigo nodularis, inflammatory scalp dermatoses, pathologic scarring, and HIV-related dermatoses. Racial differences in skin structure and function may contribute to the pathogenesis of itch in African Americans. Read More

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Development and preliminary validation of the patient-reported Chronic Itch Burden Scale, assessing health-related quality of life in chronic pruritus.

Br J Dermatol 2021 Jun 15. Epub 2021 Jun 15.

Univ Brest, LIEN and University Hospital of Brest, Department of Dermatology, 2 avenue Foch, F-29200, Brest, France.

Background: Chronic pruritus (CP) significantly affects patients' health-related quality of life (HRQoL). Very few self-reported HRQoL questionnaires exploring CP were developed according to international guidelines thus limiting their use in pre-authorization trials.

Objectives: To develop a self-reported HRQoL questionnaire in patients with CP due to psoriasis, atopic dermatitis, seborrheic dermatitis of the scalp or idiopathic dermatitis; to explore its preliminary psychometric properties. Read More

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Cutaneous manifestations related to the COVID-19 pandemic: a review article.

Cutan Ocul Toxicol 2021 Jun;40(2):168-174

Dermatology Department of Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Background: Skin lesions are either caused by COVID-19 disease or they can be due to other driving forces related to the COVID-19 pandemic.

Aim: Considering the fact that the reported data in different articles for the type and prevalence of skin manifestations related to the COVID-19 pandemic are inconsistent, we have described the mechanism and type of skin lesions related to the COVID-19 pandemic.

Methods: In this review article, we have searched the Medline database (PubMed) for the combination of the following key terms "Dermatological Manifestation", "cutaneous Manifestation", "Skin Manifestation", "COVID-19", "SARS-CoV-2". Read More

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Data mining for detecting signals of adverse drug reaction of doxycycline using the Korea adverse event reporting system database.

J Dermatolog Treat 2021 Jun 16:1-6. Epub 2021 Jun 16.

Department of Dermatology, Soonchunhyang University Hospital, Seoul, Korea.

Background: Doxycycline is one of the most prescribed antibiotics by dermatologists. However, the concern regarding adverse events of doxycyline has been rising.

Objective: To detect the adverse events of doxycycline using the Korea Adverse Events Reporting System (KAERS) database from January 2014 to December 2018 through a data mining method. Read More

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Composition of cutaneous bacterial microbiome in seborrheic dermatitis patients: A cross-sectional study.

PLoS One 2021 24;16(5):e0251136. Epub 2021 May 24.

Department of Dermatology, Erasmus Medical Centre, Rotterdam, The Netherlands.

Background: Seborrheic dermatitis (SD) is a chronic inflammatory skin disease with a multifactorial aetiology. Malassezia yeasts have been associated with the disease but the role of bacterial composition in SD has not been thoroughly investigated.

Objectives: To profile the bacterial microbiome of SD patients and compare this with the microbiome of individuals with no inflammatory skin disease (controls). Read More

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A case of cutaneous epithelioid angiosarcoma with multiple metastases.

Int J Dermatol 2021 May 5. Epub 2021 May 5.

Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea.

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Application of Cellular Resolution Full-Field Optical Coherence Tomography in vivo for the Diagnosis of Skin Tumours and Inflammatory Skin Diseases: A Pilot Study.

Dermatology 2021 May 4:1-11. Epub 2021 May 4.

Department of Dermatology, MacKay Memorial Hospital, Taipei, Taiwan.

Background: Optical coherence tomography (OCT) has been shown to provide non-invasive diagnosis of common skin neoplasms, especially basal cell carcinoma. OCT produces a cross-sectional view of the tissue, similar to a traditionally sectioned histopathological view, but the resolution of conventional OCT is low and thus limits clinical application.

Objectives: This study aimed to investigate the application ability of a full-field (FF)OCT system which was newly developed to scan the skin at the cellular level. Read More

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A Deep Learning Based Framework for Diagnosing Multiple Skin Diseases in a Clinical Environment.

Front Med (Lausanne) 2021 16;8:626369. Epub 2021 Apr 16.

Department of Dermatology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Numerous studies have attempted to apply artificial intelligence (AI) in the dermatological field, mainly on the classification and segmentation of various dermatoses. However, researches under real clinical settings are scarce. This study was aimed to construct a novel framework based on deep learning trained by a dataset that represented the real clinical environment in a tertiary class hospital in China, for better adaptation of the AI application in clinical practice among Asian patients. Read More

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Treatment of cradle cap in infants with a new cosmetic non-steroidal gel cream: Clinical, laboratory, and instrumental evaluation.

J Cosmet Dermatol 2021 Apr;20 Suppl 1:14-17

Dermatology Clinic, University of Catania, Catania, Italy.

Background: Cradle cap is a benign and self-limiting variant of seborrheic dermatitis (SD) that can be distressing for parents.

Aims: To assess by clinical/laboratory/instrumental evaluation the efficacy/tolerability of a gel cream containing piroctone olamine (antifungal), biosaccharide gum-2 (antifungal), stearyl glycyrrhetinate (anti-inflammatory), and zinc l-pyrrolidone carboxylate (zinc-PCA) (antiseborrheic) in the treatment of mild/ moderate cradle cap.

Methods: In this prospective, open-label trial, 10 infants, with mild/moderate cradle cap enrolled at the Dermatology University Clinic of Catania (Italy) used the tested gel cream twice daily for 30 days. Read More

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Dermatoses in the Elderly: Clinico-Demographic Profile of Patients Attending a Tertiary Care Centre.

Indian J Dermatol 2021 Jan-Feb;66(1):74-80

Department of Dermatology, All India Institute of Medical Sciences, Patna, Bihar, India.

Background: Elderly population is vulnerable to develop a multitude of dermatological diseases, owing to comorbidities and polypharmacies.

Objective: To know the prevalence of dermatological conditions in elderly patients attending outpatient department, determine the pattern and relative frequency of skin diseases, and find the relation with associated comorbidities.

Materials And Methods: We performed a cross-sectional study on 250 patients, aged ≥60 years. Read More

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Role of Adenosine Deaminase in Patients with Erythematotelangiectatic Rosacea and Positivity.

Iran J Parasitol 2020 Oct-Dec;15(4):596-601

Department of Medical Microbiology, Faculty of Medicine, Giresun University, Giresun, Turkey.

Background: Adenosine deaminase (ADA) is an aminohydrolase involved in the catabolism of purine nucleotides and irreversibly deaminizes adenosine and deoxyadenosine to inosine and deoxyinosine. ADA enzyme deficiency results in the loss of functional properties of B and T lymphocytes. species have been reported to be transmitted between humans through close contact and to play a role in the pathogenesis of rosacea, acne vulgaris, perioral dermatitis, seborrhoeic dermatitis, micropapillary-pruritic dermatitis and blepharitis. Read More

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Altered serum elements, antioxidants, MDA, and immunoglobulins are associated with an increased risk of seborrheic dermatitis.

Heliyon 2021 Mar 28;7(3):e06621. Epub 2021 Mar 28.

Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka, 1000, Bangladesh.

Background: The exact mechanism for the pathophysiology of seborrheic dermatitis (SD) remains unknown. According to past knowledge, neuropsychiatric disorders, weak immune responses, fungal infections, antioxidants deficiencies, and inadequate nutrition might involve in SD. Here we evaluated serum trace elements, micronutrients, antioxidants, malondialdehyde (MDA), and immunoglobulins in SD patients. Read More

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Cannabis sativa and Skin Health: Dissecting the Role of Phytocannabinoids.

Planta Med 2021 Apr 13. Epub 2021 Apr 13.

Department of Pharmacological and Biomolecular Sciences (DiSFeB), Università degli Studi di Milano, Milan, Italy.

The use of is currently recognized to ease certain types of chronic pain, reduce chemotherapy-induced nausea, and improve anxiety. Nevertheless, few studies highlighted the therapeutic potential of extracts and related phytocannabinoids for a variety of widespread skin disorders including acne, atopic dermatitis, psoriasis, pruritus, and pain. This review summarized the current evidence on the effects of phytocannabinoids at the cutaneous level through the collection of and clinical studies published on PubMed, Scopus, Embase, and Web of Science until October 2020. Read More

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Identification of species using direct PCR- sequencing on clinical samples from patients with pityriasis versicolor and seborrheic dermatitis.

Curr Med Mycol 2020 Sep;6(3):21-26

Department of Medical Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Background And Purpose: yeasts are lipophilic normal flora of the skin in humans and other warm-blooded vertebrates. This genus includes 18 species and is responsible for dermatological disorders, such as pityriasis versicolor, atopic dermatitis, seborrheic dermatitis, folliculitis, and dandruff. The aim of the present study was to identify the etiologic agents of infections among the patients referring to the Referral Dermatology Clinic of Al-Zahra Hospital, Isfahan, Iran, during 2018-2019. Read More

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September 2020

Understanding Dermatologic Concerns Among Persons Experiencing Homelessness: A Scoping Review and Discussion for Improved Delivery of Care.

J Cutan Med Surg 2021 Apr 4:12034754211004558. Epub 2021 Apr 4.

Department of Dermatology, Cumming School of Medicine, Calgary, AB, Canada.

There is a paucity of information surrounding dermatologic care for persons experiencing homelessness (PEH). This scoping review aims to map existing literature and provide a summary of the most common cutaneous manifestations among PEH, risk factors for dermatologic disease, describe any reported interventions, as well as identify research gaps for future studies. Search strategies developed for MEDLINE and hand searching yielded 486 articles. Read More

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Sensitive Scalp: A Possible Association With the Use of Hair Conditioners.

Front Med (Lausanne) 2020 15;7:596544. Epub 2021 Mar 15.

University of Brest, LIEN, Brest, France.

A sensitive scalp is defined by the occurrence of unpleasant sensations (tingling, burning, pain, pruritus) triggered by stimuli that should not cause such sensations. Environmental factors, particularly cosmetics, can be triggering factors. The aims of this study were to assess hair cosmetic product consumption in subjects with sensitive scalp and to perform a clinical evaluation of sensitive scalp. Read More

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Childhood-onset keratosis lichenoides chronica: A case report.

Clin Case Rep 2021 Mar 18;9(3):1462-1465. Epub 2021 Jan 18.

Skin Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.

Keratosis lichenoides chronica (KLC) is a rare dermatosis which represents different clinical characteristics between adult- and pediatric-onset cases. We described a childhood case of KLC with features typical for adult-onset disease. Acitretin led to partial improvement of her skin, but not mucosal, lesions. Read More

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A Novel Convolutional Neural Network for the Diagnosis and Classification of Rosacea: Usability Study.

JMIR Med Inform 2021 Mar 15;9(3):e23415. Epub 2021 Mar 15.

Department of Dermatology, Xiangya Hospital of Central South University, Changsha, China.

Background: Rosacea is a chronic inflammatory disease with variable clinical presentations, including transient flushing, fixed erythema, papules, pustules, and phymatous changes on the central face. Owing to the diversity in the clinical manifestations of rosacea, the lack of objective biochemical examinations, and nonspecificity in histopathological findings, accurate identification of rosacea is a big challenge. Artificial intelligence has emerged as a potential tool in the identification and evaluation of some skin diseases such as melanoma, basal cell carcinoma, and psoriasis. Read More

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Serum Levels of 25-Hydroxyvitamin D in Patients with Seborrheic Dermatitis: A Case-Control Study.

Dermatol Res Pract 2021 20;2021:6623271. Epub 2021 Feb 20.

Department of Dermatology, Ramsar Campus, Mazandaran University of Medical Sciences, Sari, Iran.

Several autoimmune papulosquamous skin conditions such as psoriasis, systemic lupus erythematous, and lichen planus have been associated with vitamin D deficiency or correlated with serum vitamin D level. This study was aimed at comparing the 25-hydroxyvitamin D (25(OH)D) status in patients with facial or scalp seborrheic dermatitis with healthy subjects. This case-control study included 289 patients (118 with psoriasis and 171 sex- and age-matched control subjects) from the outpatient clinic of two hospital dermatology departments in the west of Mazandaran province, Iran. Read More

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February 2021

Primary health care and family physicians provide frontline care to the dermatology patients during the era of COVID-19: Recommendations and future directions.

Badr Al-Khateeb

J Family Med Prim Care 2020 Dec 31;9(12):5862-5866. Epub 2020 Dec 31.

Chairman of Saudi Association of Public Health, Family Medicine, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences (KSAU-HS), Riyadh, Saudi Arabia.

COVID-19 has affected those disciplines where close contact is required and where there is no need for urgent care such as the field of dermatology. Due to the contagious nature of the virus, front line health care workers such as family health care physicians and primary health care doctors are using personal protective measures (PPE), which might result in skin disorders. In addition, social distancing has also resulted in the compromise of teaching and learning mainly bedside teaching in the dermatology wards. Read More

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December 2020

Isolation of different fungi from the skin of patients with seborrheic dermatitis.

Curr Med Mycol 2020 Jun;6(2):49-51

Department of Medical Laboratory Sciences, School of Paramedicine, Alborz University of Medical Sciences, Karaj, Iran.

Background And Purpose: Seborrheic dermatitis (SD) is characterized by erythematous inflammatory patches that mostly appear in the sebaceous gland-rich skin areas. In addition to the key role of species in SD, its contribution to other fungal microbiota has been recently addressed in the literature. Regarding this, the present study was conducted to identify and determine the fungal species associated with the incidence of SD. Read More

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Stem and progenitor cells in sebaceous gland development, homeostasis and pathologies.

Exp Dermatol 2021 Apr 10;30(4):588-597. Epub 2021 Mar 10.

Center for Molecular Medicine Cologne, CMMC Research Institute, University of Cologne, Cologne, Germany.

Sebaceous glands (SGs), typically associated with hair follicles, are critical for the homeostasis and function of mammalian skin. The main physiological function of SGs is the production and holocrine secretion of sebum to lubricate and protect the skin. Defective SGs have been linked to a variety of skin disorders, including acne, seborrheic dermatitis and formation of sebaceous tumors. Read More

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Cutaneous Commensal, Pathogen, or Protector?

Front Cell Infect Microbiol 2020 26;10:614446. Epub 2021 Jan 26.

Skin Research Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.

The skin microbial community is a multifunctional ecosystem aiding prevention of infections from transient pathogens, maintenance of host immune homeostasis, and skin health. A better understanding of the complex milieu of microbe-microbe and host-microbe interactions will be required to define the ecosystem's optimal function and enable rational design of microbiome targeted interventions. , a fungal genus currently comprising 18 species and numerous functionally distinct strains, are lipid-dependent basidiomycetous yeasts and integral components of the skin microbiome. Read More

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An updated review of the sebaceous gland and its role in health and diseases Part 2: Pathophysiological clinical disorders of sebaceous glands.

Dermatol Ther 2021 03 19;34(2):e14862. Epub 2021 Feb 19.

Veterans Affairs Hospital and SUNY Downstate Dermatology Service, Brooklyn, New York, USA.

Sebaceous glands are sebum-secreting components of pilosebaceous units. In the second of this two-part series, we review the pathologies in which sebaceous glands are primarily and secondarily implicated. They are primarily involved in steatocystoma simplex and multiplex, sebaceous gland hyperplasia, sebaceoma, sebaceous adenoma, sebaceous carcinoma, nevus sebaceus, and folliculosebaceous cystic hamartoma. Read More

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Host Responses in an Human Skin Model Challenged With .

Front Cell Infect Microbiol 2020 21;10:561382. Epub 2021 Jan 21.

School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.

species are a major part of the normal mycobiota and colonize mainly sebum-rich skin regions of the body. This group of fungi cause a variety of infections such as pityriasis versicolor, folliculitis, and fungaemia. In particular, and its allergens have been associated with non-infective inflammatory diseases such as seborrheic dermatitis and atopic eczema. Read More

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Phenols from L. and L. and their activity against carbonic anhydrase.

Nat Prod Res 2021 Feb 3:1-7. Epub 2021 Feb 3.

Laboratory of Pharmacognosy, School of Pharmacy, Aristotle University of Thessaloniki, Thessaloniki, Greece.

spp. are lipophilic fungi that are part of the normal flora of the human skin and are the etiological agents of dandruff and seborrheic dermatitis. β-Carbonic Anhydrases (CAs; EC 4. Read More

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February 2021

Antagonistic Activity of Antimicrobial Metabolites Produced from Seaweed-Associated Bacillus amyloliquefaciens MTCC 10456 Against Malassezia spp.

Probiotics Antimicrob Proteins 2021 Feb 1. Epub 2021 Feb 1.

Praj-Matrix - R&D Centre (Division of Praj Industries Limited) 402/403/1098, Urawade, Pirangut, Mulshi, Pune, 412115, Maharashtra, India.

Members of the genus Malassezia are known to be opportunistic pathogens responsible for causing skin disorders such as seborrheic dermatitis or dandruff, pityriasis versicolor, folliculitis, atopic dermatitis, and psoriasis. Due to the side effects caused by prolonged use of current topical antifungal agents, development of an alternative treatment is necessary. Fermentative production of antimicrobial metabolites from Bacillus amyloliquefaciens MTCC 10456 was carried out, and their antagonistic activity against Malassezia furfur and Malassezia globosa was evaluated. Read More

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February 2021

Dermatological Manifestations in Inflammatory Bowel Diseases.

J Clin Med 2021 Jan 19;10(2). Epub 2021 Jan 19.

Gastroenterology Unit, Department of Biomedical and Clinical Sciences, "L.Sacco" Hospital, 20157 Milano, Italy.

Inflammatory bowel diseases (IBDs) may be associated with extra-intestinal manifestations. Among these, mucocutaneous manifestations are relatively frequent, often difficult to diagnose and treat, and may complicate the course of the underlying disease. In the present review, a summary of the most relevant literature on the dermatologic manifestations occurring in patients with inflammatory bowel diseases has been reviewed. Read More

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January 2021

A simple technique to distinguish fibrosing alopecia in a pattern distribution from androgenetic alopecia and concomitant seborrheic dermatitis.

Bevin Bhoyrul

J Am Acad Dermatol 2021 Jan 10. Epub 2021 Jan 10.

Sinclair Dermatology, East Melbourne, Victoria, Australia. Electronic address:

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January 2021