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    1 OF 65

    The efficacy of a pseudo-ceramide and eucalyptus extract containing lotion on dry scalp skin.
    Clin Cosmet Investig Dermatol 2018 6;11:141-148. Epub 2018 Apr 6.
    Department of Dermatology, Tokyo Women's Medical University, Tokyo, Japan.
    Objective: Dry and scaly conditions on the scalp are often observed in patients with atopic dermatitis, seborrheic dermatitis and/or pityriasis capitis. Those scalp lesions often exhibit low barrier function and reduced ceramide levels. Therefore, a clinical study was conducted to evaluate the efficacy of topical application of a pseudo-ceramide and eucalyptus extract-containing lotion on the scalps of patients with skin diseases. Read More

    Causes, pathophysiology, and treatment of pruritus in the mature patient.
    Clin Dermatol 2018 Mar - Apr;36(2):140-151. Epub 2017 Oct 17.
    Department of Dermatology & Miami Itch Center at the University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA. Electronic address:
    Chronic itch is a common and debilitating health condition in the elderly. There are several common causes of itch in the mature population, such as skin xerosis, immunosenescence, and neuropathic changes. In addition, skin diseases, such as seborrheic dermatitis and stasis dermatitis, systemic conditions (end-stage renal disease and diabetes), or psychogenic derailments, such as depression, anxiety, and dementia, can all serve as triggers of pruritus. Read More

    Malassezia species retrieved from skin with pityriasis versicolor, seborrheic dermatitis and skin free of lesions: a comparison of two sampling methods.
    Br J Dermatol 2018 Mar 5. Epub 2018 Mar 5.
    Division of Microbiology, Department of Pathology, Faculty of Medicine, University of Porto, Portugal.
    Malassezia are involved in the pathogenesis of different skin diseases including pityriasis versicolor (PV) and seborrheic dermatitis (SD), but these yeasts are also important inhabitants of the skin microbiome. Culture is not performed routinely, although it may be of value in doubtful cases to support the diagnosis; culture is crucial for identification tools such as matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). Culture is also critical to assess the number of organisms and viability and, eventually, to perform antifungal susceptibility tests. Read More

    Evaluating and Optimizing the Diagnosis of Erythematotelangiectatic Rosacea.
    Dermatol Clin 2018 Apr 21;36(2):127-134. Epub 2017 Dec 21.
    University of Florida College of Medicine, PO Box 100277, Gainesville, FL 32610-0277, USA.
    Erythematotelangiectatic rosacea is the most prevalent rosacea subtype. Multiple dermatologic conditions may mimic erythematotelangiectatic rosacea. The authors review a comprehensive approach to evaluating subjects with a suspected diagnosis of erythematotelangiectatic rosacea and discuss findings that may warrant further investigation. Read More

    Cutaneous fungal microbiome: yeasts in seborrheic dermatitis scalp in a randomized, comparative and therapeutic trial.
    Dermatoendocrinol 2017 23;9(1):e1361573. Epub 2017 Oct 23.
    Department of Dermatology, Federal University of Sao Paulo (UNIFESP), São Paulo, SP, Brazil.
    spp in skin microbiome scalp has been implicated in seborrheic dermatitis pathogenesis. Thus, treatment based in antifungal combined to topical keratolitic agents have been indicated as well as oral isotretinoin as it reduces the sebum production, glandular's size and possesses anti-inflammatory properties. This randomized, comparative and therapeutic trial aimed toper form the genotypic identification of species before and after low-dose oral isotretinoin or topical antifungal treatments for moderate to severe seborrhea and/or seborrheic dermatitis on scalp. Read More

    Seeking new acne treatment from natural products, devices and synthetic drug discovery.
    Dermatoendocrinol 2017 4;9(1):e1356520. Epub 2017 Oct 4.
    Department of Dermatology, Seoul National University College of Medicine, Seoul, South Korea.
    Despite lots of research on the pathogenesis of acne, the development of new therapeutic agents is still stagnant. Conventional agents which target multiple pathological processes have some serious side effects and this makes seeking new treatment options important for treating acne. As new therapeutic options, researchers are focusing on natural products, synthetic drugs and devices. Read More

    New targets in the battle against dandruff.
    J Cosmet Sci 2017 Jan/Feb;68(1):107-113
    Lucas Meyer Cosmetics, IFF, Tour de la Cité, Québec, Canada (E.L.), Lucas Meyer Cosmetics, IFF, 31036 Toulouse Cedex 1 (E.L.), and Lucas Meyer Cosmetics, IFF, 91160 Champlan (M.B.), France.
    Dandruff is a scalp disorder characterized by flaking skin and itch of an excessive oily scalp skin. It affects 55% of the global youth and adult population. Seborrheic dermatitis is a similar scalp skin disorder with aggravated itchy rashes and flaking. Read More

    A 12-Month-Old Healthy Girl with a New Oral Ulcer and Chronic Diaper Rash.
    Dermatopathology (Basel) 2017 Jan-Dec;4(1-4):24-30. Epub 2017 Nov 16.
    Department of Dermatology, Brigham and Women's Hospital, Boston, MA, USA.
    A 12-month-old healthy girl presented with a chronic diaper rash. Physical examination demonstrated crusting of the scalp, erythematous papules with surrounding petechiae on the lower abdomen, and an intraoral palatal ulcer. Further imaging demonstrated bone involvement. Read More

    Treatment of flat and elevated pigmented disorders with a 755-nm alexandrite picosecond laser: clinical and histological evaluation.
    Lasers Med Sci 2018 Feb 9. Epub 2018 Feb 9.
    Dermatology Department, Laser Unit, Hospital Universitario Ramón y Cajal, Ctra Colmenar Viejo Km 9,100, 28034, Madrid, Spain.
    The novel picosecond lasers, initially developed for faster tattoo removal, have also shown great efficacy in endogenous pigmentary disorders. To describe the efficacy and safety profile of an alexandrite (755-nm) picosecond laser in a wide range of pigmented flat and elevated cutaneous lesions. A retrospective study was performed in which we collected all the clinical images of patients treated with the 755-nm alexandrite picosecond laser for 12 months (November 2016-November 2017). Read More

    Comparative safety and efficacy of topical mometasone furoate with other topical corticosteroids.
    Australas J Dermatol 2018 Feb 7. Epub 2018 Feb 7.
    Ego Pharmaceuticals, Braeside, Victoria, Australia.
    Derivatives of hydrocortisone, such as mometasone furoate, a (2') furoate-17 ester with chlorine substitutions at positions 9 and 21, have been designed to improve efficacy and reduce the incidence of adverse effects. An extensive literature search of MEDLINE, Embase and other databases was conducted to review the safety and efficacy of various formulations of topical mometasone furoate. Mometasone furoate exhibits high potency with greater anti-inflammatory activity and a longer duration of action than betamethasone. Read More

    Scalp Seborrheic Dermatitis and Dandruff Therapy Using a Herbal and Zinc Pyrithione-based Therapy of Shampoo and Scalp Lotion.
    J Clin Aesthet Dermatol 2018 Jan 1;11(1):26-31. Epub 2018 Jan 1.
    Dr. Barak-Shinar is Vice President of Clinical, Regulation and Quality Assurance at Kamedis Ltd. in Tel-Aviv, Israel.
    The aim of this study was to evaluate the safety and efficacy of an herbal and zinc pyrithione shampoo and a scalp lotion (Kamedis Derma-Scalp Dandruff Therapy, Kamedis Ltd., Tel Aviv, Israel) for the treatment of scalp seborrheic dermatitis and dandruff. This was an interventional, open-label, safety and efficacy study. Read More

    Pityriasis Rosea: Diagnosis and Treatment.
    Am Fam Physician 2018 Jan;97(1):38-44
    Emory University School of Medicine, Atlanta, GA, USA.
    Pityriasis rosea is a common self-limiting rash that usually starts with a herald patch on the trunk and progresses along the Langer lines to a generalized rash over the trunk and limbs. The diagnosis is based on clinical and physical examination findings. The herald patch is an erythematous lesion with an elevated border and depressed center. Read More

    Pachydermoperiostosis Masquerading as Acromegaly.
    J Endocr Soc 2017 Feb 16;1(2):109-112. Epub 2017 Jan 16.
    Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, OXE 7LE, United Kingdom.
    Context: Acromegaly usually is suspected on clinical grounds. Biochemical confirmation is required to optimize therapy, but there are other differential diagnoses.

    Case Description: We describe a 24-year-old Uzbek man who presented with many clinical symptoms and signs of apparent acromegaly. Read More

    Dermatologic manifestations among human immunodeficiency virus patients in Morocco and association with immune status.
    Int J Dermatol 2018 Feb 15;57(2):156-161. Epub 2017 Dec 15.
    Dermatology Department, Military Hospital Instruction Mohammed V, University Mohammed V, Rabat, Morocco.
    Objective: The objective was to determine if the type and number of skin diseases can be clinical indicators of underlying immune status in HIV1 disease by estimating and correlating with the CD4 count and CDC stage.

    Materials And Methods: This was a retrospective cross-sectional descriptive study. All consecutive patients infected with HIV1 followed at the Dermatology Department of Rabat Military Hospital between January 2008 and January 2017 were studied for dermatological manifestations, CD4 count and CDC clinical stage. Read More

    The Role of Moisturizers in Addressing Various Kinds of Dermatitis: A Review.
    Clin Med Res 2017 Dec 11;15(3-4):75-87. Epub 2017 Dec 11.
    Politeknik Kesehatan Jakarta, Indonesia.
    Moisturizer is a major component of basic daily skin care, particularly in presence of epidermal barrier alteration and reduced epidermal water content. It is an important part of a dermatologist's strategy to maintain skin health as well as treating various dermatoses which co-exist with skin dryness and are linked to impaired skin barrier function, such as in atopic disorders as well as other types of dermatitis. Mastering the knowledge regarding mechanism of action, application, dosage, adverse effects as well as specific clinical usage of moisturizers is a must for a dermatologist in order to support their use, particularly for evidence-based, therapeutic purposes. Read More

    Host Responses to spp. in the Mammalian Skin.
    Front Immunol 2017 22;8:1614. Epub 2017 Nov 22.
    Section of Immunology, Vetsuisse Faculty, University of Zürich, Zürich, Switzerland.
    The skin of mammalian organisms is home for a myriad of microbes. Many of these commensals are thought to have beneficial effects on the host by critically contributing to immune homeostasis. Consequently, dysbiosis can have detrimental effects for the host that may manifest with inflammatory diseases at the barrier tissue. Read More

    The genetic basis of seborrhoeic dermatitis: a review.
    J Eur Acad Dermatol Venereol 2018 Apr 15;32(4):529-536. Epub 2017 Dec 15.
    Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
    Seborrhoeic Dermatitis (SD) is a common inflammatory skin disease that presents as itchy, flaking skin in the seborrhoeic areas. Various environmental and intrinsic factors have been identified as predisposing factors for SD, but its aetiology remains poorly understood. Although it was recognized that genetic factors play a role in SD aetiology, there have not been studies that systematically review the literature specifically for causal mutations or protein deficiencies in SD. Read More

    Dasatinib-induced Seborrheic Dermatitis-like Eruption.
    J Clin Aesthet Dermatol 2017 Jul 1;10(7):23-27. Epub 2017 Jul 1.
    Dr. Riahi is with DermSurgery Associates, Houston, Texas.
    Dasatinib is an oral tyrosine kinase inhibitor approved for imatinib-resistant chronic myelogenous leukemia. It has been investigated in treating other neoplasms, including non-small-cell lung cancer and a subset of melanomas. Seborrheic dermatitis is characterized by erythematous patches or plaques with scaling typically affecting the external ear, glabella, hair-bearing areas of the face, nasolabial fold, and scalp. Read More

    Narrow-band UV-B phototherapy: an effective and reliable treatment alternative for extensive and recurrent pityriasis versicolor.
    J Dermatolog Treat 2017 Nov 9. Epub 2017 Nov 9.
    a Dermatology Department , Istanbul Medipol University Medical Faculty , Istanbul , Turkey.
    Purpose: In the previous studies, positive effect of sunlight on seborrheic dermatitis may well be explained by the direct influence of UV-light on the yeasts. Narrow-band ultraviolet-B phototherapy appears to be a very effective and safe treatment option for patients with severe seborrheic dermatitis. We aimed to investigate the efficacy of narrow-band ultraviolet-B phototherapy as an alternative treatment for pityriasis versicolor. Read More

    Mucocutaneous manifestations in human immunodeficiency virus (HIV)-infected patients in Nouakchott, Mauritania.
    Int J Dermatol 2017 Dec 27;56(12):1421-1424. Epub 2017 Sep 27.
    Research Unit of Emerging Infectious and Tropical Diseases (URMITE), Institut de Recherche pour le Développement 198, Institut Hospitalo-Universitaire - Méditerranée Infection, Aix-Marseille University, Marseille, France.
    Background: Mucocutaneous manifestations are one of the first clinical signs in patients infected with human immunodeficiency virus (HIV). To the best of our knowledge, there has been no previous study describing dermatologic manifestations in Mauritanians infected with HIV. The aim of the present study was to determine the profiles of mucocutaneous manifestations in relation to CD T cell count in HIV-positive Mauritanian patients. Read More

    In vitro activity of kombucha tea ethyl acetate fraction against species isolated from seborrhoeic dermatitis.
    Curr Med Mycol 2016 Dec;2(4):30-36
    Department of Pathobiology, Food Microbiology Division, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
    Background And Purpose: Seborrheic dermatitis is a chronic and recurrent superficial dermatitis in which species play an important role. There are different species, which have been recently reported to be resistant to common antifungals. Natural sources can be useful alternatives to reduce the emergence of this resistance. Read More

    Lipid Metabolic Versatility in spp. Yeasts Studied through Metabolic Modeling.
    Front Microbiol 2017 14;8:1772. Epub 2017 Sep 14.
    Department of Biological Sciences, Universidad de los AndesBogotá, Colombia.
    species are lipophilic and lipid-dependent yeasts belonging to the human and animal microbiota. Typically, they are isolated from regions rich in sebaceous glands. They have been associated with dermatological diseases such as seborrheic dermatitis, pityriasis versicolor, atopic dermatitis, and folliculitis. Read More

    The State of Ethnic Dermatology in Canada.
    J Cutan Med Surg 2017 Sep/Oct;21(5):464-466
    2 Division of Dermatology, Department of Medicine, University of Toronto, Toronto, ON, Canada.
    Approximately 30% of Canadians will be members of a visible minority by 2031. When dermatology became an independent medical discipline in the late 18th and early 19th centuries, most residents of Canada and the United States were of Northern European descent. Morphology and descriptions of dermatoses are based on patients with light skin. Read More

    Metabolic syndrome may be an important comorbidity in patients with seborrheic dermatitis.
    Arch Med Sci Atheroscler Dis 2016 30;1(1):e158-e161. Epub 2016 Dec 30.
    Department of Dermatology, School of Medicine of Cumhuriyet University, Sivas, Turkey.
    Introduction: Seborrheic dermatitis is a chronic inflammatory skin disease. One of the components of metabolic syndrome is inflammation, and many inflammatory cytokines play a critical role in the disease. The aim of this study is to investigate metabolic syndrome and to evaluate the relationship between the parameters of the disease and disease severity in patients with seborrheic dermatitis. Read More

    Hair and scalp disorders in adult and pediatric patients with skin of color.
    Cutis 2017 Jul;100(1):31-35
    Callender Dermatology and Cosmetic Center, Glenn Dale, Maryland, USA.
    As increasing numbers of patients of African descent seek treatment for hair and scalp-related diseases, it is imperative that all dermatologists be adequately trained to address the concerns of this patient population. We present must-know information to effectively approach the concerns of patients with seborrheic dermatitis, acquired trichorrhexis nodosa, acne keloidalis nuchae, pseudofolliculitis barbae, alopecia, and common pediatric hair and scalp disorders. Read More

    Hidradenitis Suppurativa and Concomitant Down Syndrome: Literature Review of Other Associated Mucocutaneous Manifestations in Adults.
    Skinmed 2017 1;15(4):253-258. Epub 2017 Aug 1.
    DermatoVenereology (Skin/VD) Centre, Sehgal Nursing Home, Panchwati, Delhi, India.
    This contribution describes hidradenitis suppurativa (HS) occurring in Down disease that presented with morphology conforming to an overlap of stages 1 and 2 of the Hurley staging system, namely the formation of solitary or multiple isolated abscesses without scarring or sinus tracts, recurrent abscesses, and single or multiple widely separated lesions with sinus tract formation, occupying apocrine sweat gland-bearing areas: the inner thighs, groin, and buttocks. The lesions were bilateral and symmetrical, of rare occurrence. In addition, the clinical and pathognomonic features of several other concomitant diseases are defined and reviewed; these include elastosis perforans serpiginosa, fissured tongue/macroglossia, syringomas, palmoplantar keratodermas, cheilitis, xerosis, atopic dermatitis, seborrheic dermatitis, vitiligo, cutis marmorata, and alopecia areata. Read More

    Prevalence and determinants of seborrhoeic dermatitis in a middle-aged and elderly population: the Rotterdam Study.
    Br J Dermatol 2018 Jan 8;178(1):148-153. Epub 2017 Dec 8.
    Department of Dermatology, Erasmus Medical Center, Rotterdam, the Netherlands.
    Background: Seborrhoeic dermatitis is a chronic relapsing inflammatory skin disease with unclear pathophysiological mechanisms.

    Objectives: To establish which lifestyle and physiological determinants are associated with seborrhoeic dermatitis.

    Methods: Seborrhoeic dermatitis was diagnosed by a trained physician during a full-body skin examination within the Rotterdam Study, a prospective population-based cohort study in middle-aged and elderly people. Read More

    Skin diseases of the vulva: eczematous diseases and contact urticaria.
    J Obstet Gynaecol 2018 Apr 7;38(3):295-300. Epub 2017 Aug 7.
    a Department of Dermatology , Bispebjerg Hospital , Copenhagen , Denmark.
    Skin diseases in the vulvar area include a variety of disorders many of which have a chronic course with significant morbidity. It is important to be aware of the symptoms, signs and diagnostic tools in order to optimise treatment. Herein, the most common eczematous diseases of the vulvar area, i. Read More

    Human Permanent Ectoparasites; Recent Advances on Biology and Clinical Significance of Mites: Narrative Review Article.
    Iran J Parasitol 2017 Jan-Mar;12(1):12-21
    Dept. of Medical Biology, Faculty of Medical Sciences, University of Warmia and Mazury, Olsztyn, Poland.
    Background: is a genus of mites living predominantly in mammalian pilosebaceous units. They are commonly detected in the skin of face, with increasing numbers in inflammatory lesions. Causation between mites and inflammatory diseases, such as rosacea, blepharitis, perioral and seborrhoeic dermatitis or chalazion, is controversially discussed. Read More

    [Diseases affecting the scalp].
    Cas Lek Cesk 2017 ;156(3):137-140
    The skin of the scalp differs from the skin on the other areas of the body because of a higher density of hair follicles and higher sebum production. These, together with the presence of hair, provide a suitable environment for superficial infections, infestations and inflammatory diseases. The good condition of the scalp has a significant impact on the patient's mental well-being and social interaction. Read More

    History of Seborrheic Dermatitis: Conceptual and Clinico-Pathologic Evolution.
    Skinmed 2017 1;15(3):187-194. Epub 2017 Jun 1.
    Sector of Dermatology and Post-Graduation Course in Dermatology, School of Medicine and University Hospital, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil;
    Seborrheic dermatitis is an inflammatory and chronic disease with a high incidence and prevalence (1% to 3% in the general population, 3% to 5% in young adults, and 40% to 80% in HIV-positive individuals). Although the condition was first described in 1887, its clinical aspects and clinical forms have still not been well individualized, nor has its etiopathogenesis been fully elucidated. The disease, despite having clinical features similar to dermatitis, does not have the same histopathologic features or the same progressive clinical behavior. Read More

    Delayed Treatment Response in a Neonate with Multisystem Langerhans Cell Histiocytosis Case report and review of literature.
    Sultan Qaboos Univ Med J 2017 May 20;17(2):e225-e228. Epub 2017 Jun 20.
    Department of Pediatrics, Chacha Nehru Bal Chikitsalya, New Delhi, India.
    Langerhans cell histiocytosis (LCH) is a rare proliferative disorder of the Langerhans cells, which are part of the mononuclear phagocytic system. The disorder varies in terms of the extent of the disease, its natural course and patient outcomes. While skin rashes are a common presentation of neonatal LCH, other systems or organs may also be involved. Read More

    New perspectives on dandruff and seborrheic dermatitis: lessons we learned from bacterial and fungal skin microbiota.
    Eur J Dermatol 2017 Jun;27(S1):4-7
    Centro de Ciências Naturais e Humanas (CCNH), Universidade Federal do ABC (UFABC) Avenida dos Estados, 5001 - Bangú, Santo André - SP, 09210-580, Brazil.
    The human body is inhabited by complex microbial communities, which positively impact different aspects of our health, and might also be related to the development of diseases. Progress in technologies, particularly sequencing methods and bioinformatics tools, has been crucial for the advances in this field. Microbial communities from skin can modulate immune response and protect the host against pathogens, and there are also data supporting their association with several skin conditions; including dandruff and seborrheic dermatitis. Read More

    High Colonization and Impaired Permeability Barrier in Facial Seborrheic Dermatitis.
    Chin Med J (Engl) 2017 Jul;130(14):1662-1669
    Department of Dermatology, The First Hospital of China Medical University, Shenyang, Liaoning 110001, China.
    Background: Seborrheic dermatitis (SD) is a common inflammatory skin condition. The etiology is unclear, although overgrowth of Malassezia on the skin has been suggested to cause SD. This study investigated whether colonization with Staphylococcus plays a role in facial SD, which was not well addressed previously. Read More

    Consecutive occurrence of isotopic and isomorphic response in a patient: Patchy granuloma annulare arising in the site of herpes zoster scar and seborrhoeic dermatitis.
    Australas J Dermatol 2017 Aug 3;58(3):e155-e156. Epub 2017 Jul 3.
    Cutaneous Leishmaniasis Research Center, Department of Dermatology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

    Common Allergens Identified Based on Patch Test Results in Patients with Suspected Contact Dermatitis of the Scalp.
    Skin Appendage Disord 2017 Mar 17;3(1):7-14. Epub 2016 Dec 17.
    Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA.
    Background: Contact dermatitis of the scalp is common and might be caused by many chemicals including metals, ingredients of shampoos and conditioners, dyes, or other hair treatments. Eliciting a careful history and patch tests are necessary to identify the responsible allergen and prevent relapses.

    Objectives: To identify allergens that may cause contact dermatitis of the scalp by reviewing patch test results. Read More

    Preliminary study of histamine H receptor expressed on human CD4 T cells and its immunomodulatory potency in the IL-17 pathway of psoriasis.
    J Dermatol Sci 2017 Oct 29;88(1):29-35. Epub 2017 May 29.
    Department of Dermatology, Konkuk University School of Medicine, Seoul, Republic of Korea; Research Institute of Medical Science, Konkuk University, Seoul, Republic of Korea. Electronic address:
    Background: Previous studies have shown the expression of histamine H receptor (H4R) on CD4 T cells, especially human CD4 T2-polarized T cells.

    Objective: This study aimed to investigate the role of H4R on these effector T cells in psoriasis.

    Methods: We enrolled three patients each with active psoriasis, inactive psoriasis, scalp seborrheic dermatitis, and three normal controls, and compared the basal expression of H4R mRNA in their peripheral blood CD4 T cells. Read More

    Comparison of different regimens of pimecrolimus 1% cream in the treatment of facial seborrheic dermatitis.
    J Cosmet Dermatol 2018 Feb 7;17(1):90-94. Epub 2017 Jun 7.
    Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.
    Background: Pimecrolimus 1% cream has already been proved to be an effective and safe alternative to treat seborrheic dermatitis. However, the treatment periods were inconstant in previous studies.

    Objective: To evaluate the comparative efficacy of pimecrolimus 1% cream with different regimens for the treatment of facial seborrheic dermatitis. Read More

    Potential of IL-1, IL-18 and Inflammasome Inhibition for the Treatment of Inflammatory Skin Diseases.
    Front Pharmacol 2017 22;8:278. Epub 2017 May 22.
    Department of Dermatology, University Hospital ZurichZurich, Switzerland.
    In 2002, intracellular protein complexes known as the inflammasomes were discovered and were shown to have a crucial role in the sensing of intracellular pathogen- and danger-associated molecular patterns (PAMPs and DAMPs). Activation of the inflammasomes results in the processing and subsequent secretion of the pro-inflammatory cytokines IL-1β and IL-18. Several autoinflammatory disorders such as cryopyrin-associated periodic syndromes and Familial Mediterranean Fever have been associated with mutations of genes encoding inflammasome components. Read More

    Use of Topical Corticosteroids in Dermatology: An Evidence-based Approach.
    Indian J Dermatol 2017 May-Jun;62(3):237-250
    Department of Dermatology, KPC Medical College and Hospital, Kolkata, West Bengal, India.
    Topical corticosteroids (TCs) are the pillars of dermatotherapeutics. These drugs are the "magic molecules," provided they are used judiciously and appropriately, following a rational prescription. On exhaustive literature search in multiple databases, we found a significant evidence favoring the use of TCs in atopic eczema, localized vitiligo, psoriasis, chronic hand eczema, and localized bullous pemphigoid. Read More

    Special Considerations for Therapy of Pediatric Atopic Dermatitis.
    Dermatol Clin 2017 Jul 4;35(3):351-363. Epub 2017 May 4.
    Department of Pediatric Dermatology, National Institute of Pediatrics, Insurgentes Sur 3700-C, Insurgentes Cuicuilco, México City 04530, México.
    Atopic dermatitis is the leading cause of pediatric dermatology visits in developed nations. Recurrent, itchy rashes in typical locations and a family/personal history of atopy helps to identify children with disease. Most cases (85%) are diagnosed by age 5 years. Read More

    [Psoriasis capitis and seborrhoic eczema of scalp diseases].
    Hautarzt 2017 Jun;68(6):457-465
    Hautklinik, Universitätsklinikum Erlangen, Ulmenweg 18, 91054, Erlangen, Deutschland.
    The scalp may be affected by various diseases with equally varying manifestations. Erythema and scaling is often accompanied by agonizing itch. Scalp psoriasis and seborrheic eczema represent the most frequent diseases, which can be differentiated into classical cases; however, overlap and similarities are seen. Read More

    Anti- Activity of Shell and Oil-Soluble Extracts.
    Ann Dermatol 2017 Jun 11;29(3):321-326. Epub 2017 May 11.
    Department of Dermatology, Konkuk University School of Medicine, Seoul, Korea.
    Background: A new shampoo with anti- properties obtained from various plants is required to provide seborrheic dermatitis patients with a wider range of treatment options.

    Objective: The aim of this study was to obtain susceptibility profiles of and , the most important pathogenic organisms in the development of seborrheic dermatitis, to the plant extracts used in commercial anti-dandruff shampoos.

    Methods: Minimal inhibitory concentrations (MICs) were determined for eight candidate plant extracts and two plant-derived natural products diluted with Leeming and Notman medium to final concentrations of 0. Read More

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