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    3191 results match your criteria Seborrheic Dermatitis

    1 OF 64

    Skin diseases of the vulva: eczematous diseases and contact urticaria.
    J Obstet Gynaecol 2017 Aug 7:1-6. Epub 2017 Aug 7.
    a Department of Dermatology , Bispebjerg Hospital , Copenhagen , Denmark.
    Skin diseases in the vulvar area include a variety of disorders many of which have a chronic course with significant morbidity. It is important to be aware of the symptoms, signs and diagnostic tools in order to optimise treatment. Herein, the most common eczematous diseases of the vulvar area, i. Read More

    Human Permanent Ectoparasites; Recent Advances on Biology and Clinical Significance of Demodex Mites: Narrative Review Article.
    Iran J Parasitol 2017 Jan-Mar;12(1):12-21
    Dept. of Medical Biology, Faculty of Medical Sciences, University of Warmia and Mazury, Olsztyn, Poland.
    Background: Demodex is a genus of mites living predominantly in mammalian pilosebaceous units. They are commonly detected in the skin of face, with increasing numbers in inflammatory lesions. Causation between Demodex mites and inflammatory diseases, such as rosacea, blepharitis, perioral and seborrhoeic dermatitis or chalazion, is controversially discussed. Read More

    [Diseases affecting the scalp].
    Cas Lek Cesk 2017 ;156(3):137-140
    The skin of the scalp differs from the skin on the other areas of the body because of a higher density of hair follicles and higher sebum production. These, together with the presence of hair, provide a suitable environment for superficial infections, infestations and inflammatory diseases. The good condition of the scalp has a significant impact on the patient's mental well-being and social interaction. Read More

    History of Seborrheic Dermatitis: Conceptual and Clinico-Pathologic Evolution.
    Skinmed 2017 1;15(3):187-194. Epub 2017 Jun 1.
    Sector of Dermatology and Post-Graduation Course in Dermatology, School of Medicine and University Hospital, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil;
    Seborrheic dermatitis is an inflammatory and chronic disease with a high incidence and prevalence (1% to 3% in the general population, 3% to 5% in young adults, and 40% to 80% in HIV-positive individuals). Although the condition was first described in 1887, its clinical aspects and clinical forms have still not been well individualized, nor has its etiopathogenesis been fully elucidated. The disease, despite having clinical features similar to dermatitis, does not have the same histopathologic features or the same progressive clinical behavior. Read More

    Delayed Treatment Response in a Neonate with Multisystem Langerhans Cell Histiocytosis Case report and review of literature.
    Sultan Qaboos Univ Med J 2017 May 20;17(2):e225-e228. Epub 2017 Jun 20.
    Department of Pediatrics, Chacha Nehru Bal Chikitsalya, New Delhi, India.
    Langerhans cell histiocytosis (LCH) is a rare proliferative disorder of the Langerhans cells, which are part of the mononuclear phagocytic system. The disorder varies in terms of the extent of the disease, its natural course and patient outcomes. While skin rashes are a common presentation of neonatal LCH, other systems or organs may also be involved. Read More

    New perspectives on dandruff and seborrheic dermatitis: lessons we learned from bacterial and fungal skin microbiota.
    Eur J Dermatol 2017 Jun;27(S1):4-7
    Centro de Ciências Naturais e Humanas (CCNH), Universidade Federal do ABC (UFABC) Avenida dos Estados, 5001 - Bangú, Santo André - SP, 09210-580, Brazil.
    The human body is inhabited by complex microbial communities, which positively impact different aspects of our health, and might also be related to the development of diseases. Progress in technologies, particularly sequencing methods and bioinformatics tools, has been crucial for the advances in this field. Microbial communities from skin can modulate immune response and protect the host against pathogens, and there are also data supporting their association with several skin conditions; including dandruff and seborrheic dermatitis. Read More

    High Staphylococcus epidermidis Colonization and Impaired Permeability Barrier in Facial Seborrheic Dermatitis.
    Chin Med J (Engl) 2017 Jul;130(14):1662-1669
    Department of Dermatology, The First Hospital of China Medical University, Shenyang, Liaoning 110001, China.
    Background: Seborrheic dermatitis (SD) is a common inflammatory skin condition. The etiology is unclear, although overgrowth of Malassezia on the skin has been suggested to cause SD. This study investigated whether colonization with Staphylococcus plays a role in facial SD, which was not well addressed previously. Read More

    Common Allergens Identified Based on Patch Test Results in Patients with Suspected Contact Dermatitis of the Scalp.
    Skin Appendage Disord 2017 Mar 17;3(1):7-14. Epub 2016 Dec 17.
    Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA.
    Background: Contact dermatitis of the scalp is common and might be caused by many chemicals including metals, ingredients of shampoos and conditioners, dyes, or other hair treatments. Eliciting a careful history and patch tests are necessary to identify the responsible allergen and prevent relapses.

    Objectives: To identify allergens that may cause contact dermatitis of the scalp by reviewing patch test results. Read More

    Preliminary study of histamine H4 receptor expressed on human CD4(+) T cells and its immunomodulatory potency in the IL-17 pathway of psoriasis.
    J Dermatol Sci 2017 May 29. Epub 2017 May 29.
    Department of Dermatology, Konkuk University School of Medicine, Seoul, Republic of Korea; Research Institute of Medical Science, Konkuk University, Seoul, Republic of Korea. Electronic address:
    Background: Previous studies have shown the expression of histamine H4 receptor (H4R) on CD4(+) T cells, especially human CD4(+) Th2-polarized T cells.

    Objective: This study aimed to investigate the role of H4R on these effector T cells in psoriasis.

    Methods: We enrolled three patients each with active psoriasis, inactive psoriasis, scalp seborrheic dermatitis, and three normal controls, and compared the basal expression of H4R mRNA in their peripheral blood CD4(+) T cells. Read More

    Comparison of different regimens of pimecrolimus 1% cream in the treatment of facial seborrheic dermatitis.
    J Cosmet Dermatol 2017 Jun 7. Epub 2017 Jun 7.
    Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.
    Background: Pimecrolimus 1% cream has already been proved to be an effective and safe alternative to treat seborrheic dermatitis. However, the treatment periods were inconstant in previous studies.

    Objective: To evaluate the comparative efficacy of pimecrolimus 1% cream with different regimens for the treatment of facial seborrheic dermatitis. Read More

    Potential of IL-1, IL-18 and Inflammasome Inhibition for the Treatment of Inflammatory Skin Diseases.
    Front Pharmacol 2017 22;8:278. Epub 2017 May 22.
    Department of Dermatology, University Hospital ZurichZurich, Switzerland.
    In 2002, intracellular protein complexes known as the inflammasomes were discovered and were shown to have a crucial role in the sensing of intracellular pathogen- and danger-associated molecular patterns (PAMPs and DAMPs). Activation of the inflammasomes results in the processing and subsequent secretion of the pro-inflammatory cytokines IL-1β and IL-18. Several autoinflammatory disorders such as cryopyrin-associated periodic syndromes and Familial Mediterranean Fever have been associated with mutations of genes encoding inflammasome components. Read More

    Use of Topical Corticosteroids in Dermatology: An Evidence-based Approach.
    Indian J Dermatol 2017 May-Jun;62(3):237-250
    Department of Dermatology, KPC Medical College and Hospital, Kolkata, West Bengal, India.
    Topical corticosteroids (TCs) are the pillars of dermatotherapeutics. These drugs are the "magic molecules," provided they are used judiciously and appropriately, following a rational prescription. On exhaustive literature search in multiple databases, we found a significant evidence favoring the use of TCs in atopic eczema, localized vitiligo, psoriasis, chronic hand eczema, and localized bullous pemphigoid. Read More

    Special Considerations for Therapy of Pediatric Atopic Dermatitis.
    Dermatol Clin 2017 Jul 4;35(3):351-363. Epub 2017 May 4.
    Department of Pediatric Dermatology, National Institute of Pediatrics, Insurgentes Sur 3700-C, Insurgentes Cuicuilco, México City 04530, México.
    Atopic dermatitis is the leading cause of pediatric dermatology visits in developed nations. Recurrent, itchy rashes in typical locations and a family/personal history of atopy helps to identify children with disease. Most cases (85%) are diagnosed by age 5 years. Read More

    In Vitro Anti-Malassezia Activity of Castanea crenata Shell and Oil-Soluble Glycyrrhiza Extracts.
    Ann Dermatol 2017 Jun 11;29(3):321-326. Epub 2017 May 11.
    Department of Dermatology, Konkuk University School of Medicine, Seoul, Korea.
    Background: A new shampoo with anti-Malassezia properties obtained from various plants is required to provide seborrheic dermatitis patients with a wider range of treatment options.

    Objective: The aim of this study was to obtain in vitro susceptibility profiles of Malassezia restricta and M. globosa, the most important pathogenic organisms in the development of seborrheic dermatitis, to the plant extracts used in commercial anti-dandruff shampoos. Read More

    Hydrocortisone 1% cream and sertaconazole 2% cream to treat facial seborrheic dermatitis: A double-blind, randomized clinical trial.
    Int J Womens Dermatol 2017 Jun 23;3(2):107-110. Epub 2016 Dec 23.
    Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.
    Background: Seborrheic dermatitis (SD) is a chronic dermatitis with periods of remission and relapse that requires long-term treatment.

    Objective: We compared the efficacy and safety of treatment with sertaconazole with standard corticosteroid medications in adults with facial SD.

    Methods: In this double-blind, randomized controlled trial, 60 patients with a diagnosis of SD were enrolled. Read More

    Erythromelalgia involving the face.
    Dermatol Online J 2017 Apr 15;23(4). Epub 2017 Apr 15.
    Baylor College of Medicine, Houston, Texas.
    Erythromelalgia is a rare disorder characterized by burning pain, erythema, and increased temperature typically involving the distal extremities. Although it can progress to involve the face, erythromelalgia presenting only on the face is particularly rare. This disorder is often misdiagnosed when it presents on the extremities and is even more likely to be misdiagnosed when presenting only on the face, delaying appropriate treatment and causing considerable frustration for the patient. Read More

    Severe pellagra masked by concurrent plaque psoriasis: a case report of a hidden diagnosis.
    Dermatol Online J 2017 May 15;23(5). Epub 2017 May 15.
    Department of Dermatology, School of Medicine, University of California, Davis, Sacramento, California.
    Despite characteristic features, psoriasis can mimic other dermatologic conditions, such as seborrheic dermatitis, lichen simplex chronicus, and certain nutritional deficiencies such as pellagra. We present a patient with a longstanding history of severe plaque psoriasis who presented with disfiguring scaly plaques involving greater than 80% body surface area. The patient's disease was minimally responsive to multiple therapies. Read More

    Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    J Cosmet Dermatol 2017 May 14. Epub 2017 May 14.
    The Procter & Gamble Company, Cincinnati, OH, USA.
    Objectives: To determine whether the oxidative stress transmitted to newly grown hair from an unhealthy scalp has physical consequences to the cuticular condition and function.

    Methods: A uniquely designed 24-week clinical study included 8 weeks of pretreatment with a cosmetic shampoo and 16 weeks of treatment with either a potentiated zinc pyrithione (ZPT) antidandruff shampoo or a placebo cosmetic shampoo. This clinical design allowed the growth and acquisition of hair samples under conditions of varying but known scalp health as a result of treating a dandruff/seborrheic dermatitis (D/SD) population. Read More

    Treatment of Seborrheic Dermatitis Using a Novel Herbal-based Cream.
    J Clin Aesthet Dermatol 2017 Apr;10(4):17-23
    George Washington University School of Medicine, Washington, D.C.
    Objective: Seborrheic dermatitis is a common relapsing inflammatory skin condition occurring in approximately 3 to 5 percent of the general population. Current available therapies control, but do not cure seborrhea. The study's objective was to determine the safety and efficacy of a barrier-based, nonsteroidal cream incorporating herbal extracts as a treatment for facial seborrheic dermatitis. Read More

    [Cutaneous myiasis due to Cochliomyia hominivorax associated with seborrheic dermatitis].
    Rev Med Chil 2017 Feb;145(2):250-254
    Laboratorio de Parasitología Básico-Clínico, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
    Myiasis is an infestation of tissues and organs of humans and animals by Diptera larvae (flies, horseflies, mosquitoes). They are located at different body sites, and classified clinically as cutaneous, visceral and cavitary. We report a 26-year-old woman with a history of seborrheic dermatitis and recent trip to Brazil. Read More

    Advances in pharmacotherapeutic management of common skin diseases in neonates and infants.
    Expert Opin Pharmacother 2017 May 21;18(7):717-725. Epub 2017 Apr 21.
    a Dermatology, Department of Experimental, Diagnostic and Specialty Medicine , Sant'Orsola-Malpighi Hospital, University of Bologna , Bologna , Italy.
    Introduction: neonatal and infantile skin diseases are frequently encountered in the clinical practice and represent worldwide a socioeconomic issue. They encompass a wide range of acquired or congenital conditions, including infections, vascular lesions and inflammatory diseases and can present with different degrees of severity, leading in some cases to dramatic complications. Areas covered: In this paper we report the most recent evidences on the management of some common skin diseases in neonates and infants. Read More

    Differential Diagnosis of Diaper Dermatitis.
    Clin Pediatr (Phila) 2017 May;56(5_suppl):16S-22S
    1 Johns Hopkins Children's Center, Baltimore, MD, USA.
    Mild diaper dermatitis often occurs in children before toilet training is complete, particularly from 9 to 12 months of age, and the most common presentation is an irritant contact dermatitis. Diaper dermatitis may account for up to 25% of dermatology visits to health care providers during the first year of life. Fortunately, since the introduction of hypoallergenic, superabsorbent modern disposable diapers, the incidence and severity of irritant and allergic contact dermatitis has decreased dramatically. Read More

    Association of Dermatoses with Duration and Quantum of Alcohol Intake: A Comparative Cross-sectional Study.
    Indian J Dermatol 2017 Mar-Apr;62(2):184-190
    Department of Dermatology, Dr. D.Y. Patil Medical College and Hospital, Pune, Maharashtra, India.
    Background: Chronic alcohol intake impacts skin directly, through organ dysfunction or by modifying preexisting dermatoses. However, dermatoses afflicting chronic alcoholics figure in a few studies only.

    Aim: This study aims to correlate the spectrum of dermatoses in chronic alcoholics with the quantum/duration of alcohol intake and raised liver transaminases. Read More

    Targeting Malassezia species for novel synthetic and natural antidandruff agents.
    Curr Med Chem 2017 Apr 4. Epub 2017 Apr 4.
    Neurofarba Dept., Section of Pharmaceutical and Nutriceutical Sciences, Università degli Studi di Firenze, Via U. Schiff 6, 50019 Sesto Fiorentino (Florence). Italy.
    Malassezia spp. are lipophilic yeasts not only present in the normal skin microflora, but also responsible of skin-related diseases (pityriasis versicolor, seborrheic/atopic dermatitis and dandruff) as well as systemic fungal infections in humans and animals. Their treatment and eradication are mainly based on old azole drugs, which are characterized by poor compliance, unpredictable clinical efficacy, emerging resistance and several side effects. Read More

    Knowledge and Behavior Regarding Cosmetics in Koreans Visiting Dermatology Clinics.
    Ann Dermatol 2017 Apr 24;29(2):180-186. Epub 2017 Mar 24.
    Arumdaun Nara Clinic, Seoul, Korea.
    Background: Cosmetics can affect the skin condition profoundly, and yet no survey has been performed in Koreans visiting dermatology clinics.

    Objective: To assess knowledge and consumer behavior regarding cosmetics in Koreans visiting dermatology clinics.

    Methods: A questionnaire consisting of 43 questions concerning demographics and use/knowledge/selection/purchase of cosmetics was given to patients and accompanying persons who visited dermatologic clinics in university and private clinic settings. Read More

    [How I explore… scalp and hairin erythemato-squamous disorders].
    Rev Med Liege 2016 Oct;71(10):460-462
    Service de Dermatopathologie, CHU de Liège, Belgique.
    In their early stages, some dermatoses of the scalp such as psoriasis seborrheic dermatitis, tinea capitis and discoid lupus erythematosus are often hardly noticeable to others. However, the eruptions are occasionally severe and extensive. Reaching an adequate diagnosis is of utmost impor¬tance for an adequate healthcare. Read More

    Real-Time PCR Identification of Six Malassezia Species.
    Curr Microbiol 2017 Jun 22;74(6):671-677. Epub 2017 Mar 22.
    Fungal and Parasitic Molecular Biology Laboratory, Faculty of Medicine, University of Sfax, Rue Magida Boulila, Sfax, 3029, Tunisia.
    Lipophilic yeast Malassezia species is widely found on the skin surface of humans and other animals. This fungus can cause pityriasis versicolor, Malassezia folliculitis, and seborrheic dermatitis. Still now, there is a problem with species identification of Malassezia with conventional methods. Read More

    Skin disorders in Parkinson's disease: potential biomarkers and risk factors.
    Clin Cosmet Investig Dermatol 2017 9;10:87-92. Epub 2017 Mar 9.
    Department of Dermatology and Allergy, Herlev and Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.
    Parkinson's disease (PD) is one of the most common neurodegenerative disorders, characterized by a symptom triad comprising resting tremor, rigidity, and akinesia. In addition, non-motor symptoms of PD are well recognized and often precede the overt motor manifestations. Cutaneous manifestations as markers of PD have long been discussed, and cumulative evidence shows an increased prevalence of certain dermatological disorders in PD. Read More

    Global Skin Disease Morbidity and Mortality: An Update From the Global Burden of Disease Study 2013.
    JAMA Dermatol 2017 May;153(5):406-412
    Institute for Health Metrics and Evaluation, University of Washington, Seattle.
    Importance: Disability secondary to skin conditions is substantial worldwide. The Global Burden of Disease Study 2013 includes estimates of global morbidity and mortality due to skin diseases.

    Objective: To measure the burden of skin diseases worldwide. Read More

    Common spongiotic dermatoses.
    Semin Diagn Pathol 2017 May 10;34(3):226-236. Epub 2017 Feb 10.
    Department of Radiation Oncology, The Ohio State University, Columbus, OH, USA.
    This review article focuses on the spongiotic tissue reaction pattern and some of the common entities that practicing pathologists can frequently encounter in their practice. The spongiotic tissue reaction pattern is the single most common one encountered in the routine analysis of inflammatory dermatoses, and the most non-specific one as well. Spongiotic dermatoses include a very large list of disorders which are best grouped under neutrophilic, eosinophilic, miliarial, follicular and pityriasiform forms of spogiosis. Read More

    Common Skin Conditions in Children: Neonatal Skin Lesions.
    FP Essent 2017 Feb;453:11-17
    University of North Carolina Chapel Hill School of Medicine Dermatology Residency Program, 410 Market St. Suite 400 CB#7715, Chapel Hill, NC 27516.
    Skin findings during the initial month of life are ubiquitous. One study estimated that more than 95% of newborns have cutaneous findings, which often are distressing to parents but frequently are benign and self-limited. Among them are milia, cutis marmorata, congenital dermal melanocytosis, and the benign neonatal pustular eruptions (eg, benign cephalic pustulosis, erythema toxicum neonatorum, transient neonatal pustular melanosis). Read More

    Estrogenic activity of zinc pyrithione: An in vivo and in vitro study.
    Environ Health Toxicol 2017 Feb 9. Epub 2017 Feb 9.
    Department of Bio Health Science, Changwon National University , Changwon-si, Gyeongnam , Korea.
    Objectives: Zinc pyrithione is commonly used to prevent dandruff and seborrheic dermatitis. Many consumers are exposed daily to high doses of zinc pyrithione, causing serious concerns about its toxicity. The reproductive and developmental toxicities were previously reported in pregnant rats. Read More

    Distribution of Malassezia Species in Patients with Different Dermatological Disorders and Healthy Individuals.
    Acta Dermatovenerol Croat 2016 Dec;24(4):274-281
    Professor Asja Prohić, MD, PhD, Department of Dermatovenerology, University Clinical Center of Sarajevo, Bolnicka 25, 71000 Sarajevo, Bosnia and Herzegovina;
    There are differences with respect to the commonly isolated Malassezia species, not only between healthy individuals and the patients with various skin diseases, but also between different countries. We investigated the species composition of Malassezia microflora on the skin of patients with Malassezia-associated diseases and of healthy subjects (HS). Two hundred and fifty skin scrapings from patients with pityriasis versicolor (PV), seborrheic dermatitis (SD), atopic dermatitis (AD), psoriasis (PS), and healthy subjects (HS), fifty each, were inoculated into Sabouraud dextrose agar and into modified Dixon agar and identified using conventional culture-based methods. Read More

    A novel cosmetic antifungal/anti-inflammatory topical gel for the treatment of mild to moderate seborrheic dermatitis of the face: a open-label trial utilizing clinical evaluation and erythemadirected digital photography.
    G Ital Dermatol Venereol 2017 Jan 24. Epub 2017 Jan 24.
    Dermatology Clinic, University of Catania, Catania, Italy -
    Bakground: Topical cosmetic agents may play a role in the management of facial seborrheic dermatitis by reducing inflammation and scale production. Advanced digital photography, equipped with technology able to provide a detailed evaluation of red skin components corresponding to vascular flare (erythema-directed digital photography), is a useful tool for evaluation of erythema in patients affected by inflammatory dermatoses. The aim of this study was to assess the efficacy and safety of a new cosmetic topical gel containing ciclopiroxolamine, lactoferrin, glycero-phosphoinositol (GPI) and Aloe vera, for the treatment of facial seborrheic dermatitis by clinical and advanced digital photography evaluation. Read More

    The mPEG-PCL Copolymer for Selective Fermentation of Staphylococcus lugdunensis Against Candida parapsilosis in the Human Microbiome.
    J Microb Biochem Technol 2016 Aug 19;8(4):259-265. Epub 2016 Jun 19.
    Department of Dermatology, University of California, San Diego, CA, USA; Moores Cancer Center; University of California, San Diego, CA, USA.
    Many human skin diseases, such as seborrheic dermatitis, potentially occur due to the over-growth of fungi. It remains a challenge to develop fungicides with a lower risk of generating resistant fungi and non-specifically killing commensal microbes. Our probiotic approaches using a selective fermentation initiator of skin commensal bacteria, fermentation metabolites or their derivatives provide novel therapeutics to rein in the over-growth of fungi. Read More

    Collapse of human scalp microbiome network in dandruff and seborrhoeic dermatitis.
    Exp Dermatol 2017 Jan 17. Epub 2017 Jan 17.
    Skin Research Institute, Amorepacific Corporation R&D Center, Yongin, Korea.
    We investigate the relationship between scalp microbiota and dandruff/seborrhoeic dermatitis (D/SD), an unpleasant scalp disorder common in human populations. Bacterial and fungal community analyses on scalp of 102 Korean were performed by next-generation sequencing. Overall scalp microbiome composition significantly differed between normal and disease groups, and especially co-occurrence network of dominant members was breakdown in disease groups. Read More

    Prevalence of hormonal and endocrine dysfunction in patients with lichen planopilaris (LPP): A retrospective data analysis of 168 patients.
    J Am Acad Dermatol 2017 Feb;76(2):314-320
    Department of Dermatology, Cleveland Clinic Foundation, Cleveland, Ohio. Electronic address:
    Background: Studies on the pathophysiology and comorbidities associated with lichen planopilaris (LPP) and frontal fibrosing alopecia (FFA) are limited.

    Objective: The purpose of this study was to determine the prevalence of androgen excess in the postmenopausal LPP population, in relation to demographics and comorbidities.

    Methods: A retrospective data analysis of 413 patients with LPP, FFA, and LPP/FFA seen in the Department of Dermatology at the Cleveland Clinic Foundation in Ohio between 2005 and 2015 was conducted. Read More

    Cutaneous features of myotonic dystrophy types 1 and 2: Implication of premature aging and vitamin D homeostasis.
    Neuromuscul Disord 2017 Feb 16;27(2):163-169. Epub 2016 Nov 16.
    Department of Systems Medicine, Division of Neurology, University of Rome Tor Vergata, Viale Oxford 81, 00133 Rome, Italy; Department of Experimental Medicine and Surgery, Division of Clinical Biochemistry, University of Rome Tor Vergata, Viale Oxford 81, 00133 Rome, Italy. Electronic address:
    Skin changes have been described in myotonic dystrophy type 1 (DM1). However, whether and in which way skin is a target of specific disease alterations in DM1 and DM2 has not been yet clarified. This study aims to explore cutaneous features of DM1 and DM2 patients. Read More

    Diversity in Dermatology Clinical Trials: A Systematic Review.
    JAMA Dermatol 2017 Jan 4. Epub 2017 Jan 4.
    Department of Dermatology, Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts.
    Importance: Though there have been significant shifts in US demographic data over the past 50 years, research cohorts lack full racial and ethnic representation. There is little data available regarding the diversity of dermatology research cohorts with respect to sex, race, and ethnicity.

    Objective: To characterize and assess the representation of racial and ethnic minorities and women in randomized controlled trials across a range of dermatologic conditions. Read More

    Nekam's disease.
    Indian Dermatol Online J 2016 Nov-Dec;7(6):520-522
    Department of DVL, Katuri Medical College, Guntur, Andhra Pradesh, India.
    Keratosis lichenoides chronica also known as Nekam's disease is a rare mucocutaneous disorder, characterized clinically by asymptomatic violaceous keratotic papules arranged in linear, reticular, or plaque form usually on the trunk and extremities and histologically by interface dermatitis. The disease is considered rare with only 128 cases being reported in the literature till date and very few from India. We report a case of a 40-year-old man who presented with constellation of features of lichen planus, seborrheic dermatitis, and apthous ulcers, which upon workup was found to be Nekam's disease. Read More

    Recent Advances in Pharmacotherapeutic Paradigm of Mild to Recalcitrant Atopic Dermatitis.
    Crit Rev Ther Drug Carrier Syst 2016 ;33(3):213-263
    Department of Pharmacology, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz 50300, Kuala Lumpur, Malaysia.
    Atopic dermatitis (AD) is a common, chronic skin inflammatory disorder characterized by perivascular infiltration of immunoglobulin E (IgE), T lymphocytes, and mast cells. The key factors responsible for the pathophysiology of this disease are immunological disorders and defects in epidermal barrier properties. Pruritus, intense itching, psychological stress, deprived physical and mental performance, and sleep disturbance are the hallmark features of this dermatological disorder. Read More

    Efficacy and Safety of Cream Containing Climbazole/Piroctone Olamine for Facial Seborrheic Dermatitis: A Single-Center, Open-Label Split-Face Clinical Study.
    Ann Dermatol 2016 Dec 23;28(6):733-739. Epub 2016 Nov 23.
    Department of Dermatology, Konkuk University School of Medicine, Seoul, Korea.; Research Institute of Medical Science, Konkuk University, Seoul, Korea.
    Background: Seborrheic dermatitis (SD) is a multifactorial disease; Malassezia species play an important role in its pathogenesis.

    Objective: We aimed to determine whether a cream containing climbazole/piroctone olamine (C/P cream), antifungal agents with expected efficacy against Malassezia species, could improve SD symptoms.

    Methods: We instructed 24 patients with mild-to-moderate SD to apply the C/P cream and emollient cream on the right and left sides of the face, respectively, every morning and evening for 4 weeks. Read More

    Study of infections among human immunodeficiency virus/acquired immunodeficiency syndrome patients in Shadan Hospital, Telangana, India.
    Indian J Sex Transm Dis 2016 Jul-Dec;37(2):147-150
    Department of Dermatology and STD, Shadan Institute of Medical Sciences, Teaching Hospital and Research Centre (A Post Graduate Institute), Hyderabad, Telangana, India.
    Background: Human immunodeficiency virus (HIV) pandemicity is a major concern today as it causes greater loss of productivity than any other disease. HIV infection leads to profound immune deficiency and patients become highly susceptible to opportunistic infections (OIs). HIV epidemic in India is heterogeneous in nature, both in terms of routes of transmission as well as geographical spread. Read More

    Whole genome sequencing analysis of the cutaneous pathogenic yeast Malassezia restricta and identification of the major lipase expressed on the scalp of patients with dandruff.
    Mycoses 2017 Mar 24;60(3):188-197. Epub 2016 Nov 24.
    Department of Systems Biotechnology, Chung-Ang University, Anseong, Korea.
    Malassezia species are opportunistic pathogenic fungi that are frequently associated with seborrhoeic dermatitis, including dandruff. Most Malassezia species are lipid dependent, a property that is compensated by breaking down host sebum into fatty acids by lipases. In this study, we aimed to sequence and analyse the whole genome of Malassezia restricta KCTC 27527, a clinical isolate from a Korean patient with severe dandruff, to search for lipase orthologues and identify the lipase that is the most frequently expressed on the scalp of patients with dandruff. Read More

    Non-dermatophyte Dermatoses Mimicking Dermatophytoses in Animals.
    Mycopathologia 2017 Feb 16;182(1-2):113-126. Epub 2016 Nov 16.
    UP Interactions Cellules Environnement, VetAgro Sup, Univ Lyon, 69280, Marcy l'Etoile, France.
    Dermatophytoses in animals are fungal diseases of the skin caused by dermatophyte fungi of the genus Microsporum or Trichophyton. Because the infection is generally follicular, the most common clinical sign is one or many circular areas of alopecia with variable erythema, scaling and crusting, and the primary differential diagnoses are follicular infections, such as bacterial folliculitis and demodicosis. Although dermatophyte folliculitis or ringworm is the most commonly observed lesion of dermatophytoses in animals, other presentations may be observed according to the host species and the dermatophyte involved: dermatophyte folliculitis or ringworm, scaling and crusting in dermatophytosis due to Microsporum persicolor, nodule in case of kerion or mycetoma, matted hairs, seborrheic dermatosis or miliary dermatitis in cats, generalized exfoliative dermatoses in dogs, cats and horses, superficial non-follicular pustules, papules and macules in the Devon Rex cat, pruritic dermatophytoses in dogs, cats and horses, and onychomycosis in dogs, cats and horses. Read More

    Pityriasis amiantacea: a study of seven cases.
    An Bras Dermatol 2016 Sep-Oct;91(5):694-696
    Universidade Federal do Rio de Janeiro (UFRJ) - Rio de Janeiro (RJ), Brazil.
    Pityriasis amiantacea was first described in 1832. The disease may be secondary to any skin condition that primarily affects the scalp, including seborrheic dermatitis. Its pathogenesis remains uncertain. Read More

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