3,672 results match your criteria Seborrheic Dermatitis


Frontal Fibrosing Alopecia - a review and a practical guide for clinicians.

Ann Agric Environ Med 2022 Jun 31;29(2):169-184. Epub 2021 Aug 31.

Cutaneous Histopathology and Immunopathology Section, Department of Dermatology, Poznan University of Medical Sciences, Poznan, Poland.

Despite a significant increase in reported cases of frontal fibrosing alopecia (FFA) in literature, discussion about the possible role of environmental factors, instruction for diagnosis and guideline for treatment, are limited. The review aims to provide a detailed synthesis of this condition that could be used by clinicians in their practise. Whether single-centre or multi-centre, studies of more than 60 cases less than 5 years old were mainly taken into consideration. Read More

View Article and Full-Text PDF

[Occupational Dermatoses in Healthcare Workers during the COVID-19 Pandemic: A Narrative Review].

Acta Med Port 2022 Jun 29. Epub 2022 Jun 29.

Gabinete de Medicina do Trabalho. Instituto Português de Oncologia do Porto. Porto. Portugal.

Introduction: On the 11th March 2020, the World Health Organization declared the novel coronavirus outbreak as a pandemic. Preventive measures such as the appropriate use of personal protective equipment and proper hand hygiene are essential in decreasing transmissibility. Healthcare workers have been required to wear personal protective equipment and to wash their hands even more frequently. Read More

View Article and Full-Text PDF

Lichen Planopilaris Arising between Two Linear Surgical Scars.

Int J Trichology 2022 May-Jun;14(3):112-114. Epub 2022 May 24.

Department of Dermatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Lichen planopilaris (LPP) is a type of lymphocytic cicatricial alopecia, which can occur at unusual sites. It can be difficult to diagnose at an early stage and may be misdiagnosed as seborrheic dermatitis or psoriasis in early stages before alopecia occurs. We report a rare case in which alopecia occurred between two long surgical scars on the scalp several years after surgery. Read More

View Article and Full-Text PDF

Malassezia virulence factors and their role in dermatological disorders.

Acta Dermatovenerol Alp Pannonica Adriat 2022 Jun;31(2):65-70

Department of Biochemistry, Faculty of Medicine and Health Sciences, Christian University of Krida Wacana (UKRIDA), Jakarta, Indonesia.

Malassezia is a commensal fungus that constitutes normal skin microbiota. However, in certain conditions and individuals, it may transform into a pathogenic yeast with multiple associated dermatological disorders and various clinical manifestations. This phenomenon is influenced by a unique host-agent interaction that triggers the production of several virulence factors, such as indoles, reactive oxygen species, azelaic acid, hyphae formation, and biofilm formation. Read More

View Article and Full-Text PDF

Influence of Oil Polarity and Cosurfactants on the Foamability of Mono- and Diacylphosphatidylcholine Stabilized Emulsions.

Pharmaceutics 2022 Jun 7;14(6). Epub 2022 Jun 7.

Department of Pharmaceutical Technology, Eberhard Karls University, Auf der Morgenstelle 8, 72076 Tuebingen, Germany.

Foam formulations are safe and effective therapy options for the treatment of chronic skin conditions that require the application of a topical formulation to delicate skin areas, such as scalp psoriasis or seborrheic dermatitis. This study focused on the development of foamable emulsions based on aqueous phospholipid blends. The effects of cosurfactants (nonionic Lauryglucoside (LG); zwitterionic Lauramidopropyl betaine (LAPB)), as well as of oil phases of different polarities, namely paraffin oil (PO), medium-chain triglycerides (MCT) and castor oil (CO), were investigated. Read More

View Article and Full-Text PDF

Overview of use, efficacy, and safety of dupilumab in complex patients: a retrospective, case-series study from a large, urban academic center.

Arch Dermatol Res 2022 Jun 18. Epub 2022 Jun 18.

Department of Dermatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02215, USA.

Dupilumab has emerged as an effective treatment option for those suffering from moderate-to-severe atopic dermatitis (AD). Since its approval in 2017 by the United States Food and Drug Administration, dupilumab demonstrated efficacy in a wide range of "off-label" dermatologic conditions. With its increasing use, dermatologists must navigate prescribing dupilumab in complex patient populations. Read More

View Article and Full-Text PDF

Identification of Malassezia species isolated from some Malassezia associated skin diseases.

J Mycol Med 2022 Jun 7;32(4):101301. Epub 2022 Jun 7.

Microbiology Department, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.

Background: The genus Malassezia represents the dominant eukaryotic component of the skin microbial flora. There are complex interactions between this commensal and the skin, leading to various Malassezia-caused or Malassezia exacerbated skin conditions.

Objectives: To identify Malassezia species in lesions of patients with pityriasis versicolor (PV), atopic dermatitis (AD), and seborrheic dermatitis (SD), as well as corresponding sites in healthy subjects according to the culture methods used for Malassezia species isolation. Read More

View Article and Full-Text PDF

Perialar intertrigo in children and adolescents: A multicenter prospective study of 41 cases.

Pediatr Dermatol 2022 Jun 14. Epub 2022 Jun 14.

Department of Dermatology-Venereology, Hôpital Archet 2, CHU de Nice, Nice, France.

Background/objectives: We observed isolated cases of perialar intertrigo in children and teenagers that did not appear to correspond to any known clinical entity. The objective of this study was to describe the clinical features of this dermatosis and the clinical characteristics of the patients.

Methods: We conducted a prospective, multicenter cohort study in France from August 2017 to November 2019. Read More

View Article and Full-Text PDF

Genome of Malassezia arunalokei and Its Distribution on Facial Skin.

Microbiol Spectr 2022 Jun 1;10(3):e0050622. Epub 2022 Jun 1.

Department of Systems Biotechnology, Chung-Ang Universitygrid.254224.7, Anseong, South Korea.

is a fungal genus found on the skin of humans and warm-blooded animals, with 18 species reported to date. In this study, we sequenced and annotated the genome of Malassezia arunalokei, which is the most recently identified species, and compared it with Malassezia restricta, the predominant isolate from human skin. Additionally, we reanalyzed previously reported mycobiome data sets with a species-level resolution to investigate distribution within the mycobiota of human facial skin. Read More

View Article and Full-Text PDF

Association Between Hair Diseases and COVID-19 Pandemic-Related Stress: A Cross-Sectional Study Analysis.

Front Med (Lausanne) 2022 12;9:876561. Epub 2022 May 12.

Public Health Foundation, Dhaka, Bangladesh.

Introduction: Psychological stress from the ongoing coronavirus disease 2019 (COVID-19) pandemic can potentially aggravate the course of several stress-sensitive skin and hair diseases. This study aimed to determine the potential association of COVID-19 stress with hair diseases, such as telogen effluvium (TE), alopecia areata (AA), and seborrheic dermatitis (SD), among medical students in Bangladesh.

Methods: This online-based cross-sectional study was conducted among 404 medical students of Bangladesh using a self-administered questionnaire, including sociodemographic information, status of hair diseases (i. Read More

View Article and Full-Text PDF

Novel detection method involving non-invasive sebum collection and next-generation sequencing.

Postepy Dermatol Alergol 2022 Apr 16;39(2):321-326. Epub 2021 Jul 16.

Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland.

Introduction: mites are common human ectoparasites found across a broad geographical range. They reside in pilosebaceous units of the skin and feed on sebum, epithelial and glandular cells. is the more common mite, inhabiting the upper end of the pilosebaceous unit while resides deeper in the skin and meibomian glands. Read More

View Article and Full-Text PDF

Skin microbiome signatures associated with psoriasis and seborrheic dermatitis.

Exp Dermatol 2022 May 31. Epub 2022 May 31.

Department of Dermatology, Peking University First Hospital, Beijing, China.

View Article and Full-Text PDF

Multi-Modal Imaging to Assess the Follicular Delivery of Zinc Pyrithione.

Pharmaceutics 2022 May 17;14(5). Epub 2022 May 17.

Therapeutics Research Centre, UniSA-Clinical and Health Sciences, University of South Australia, Adelaide, SA 5000, USA.

Zinc pyrithione (ZnPT) is a widely used antifungal, usually applied as a microparticle suspension to facilitate delivery into the hair follicles, where it then dissociates into a soluble monomeric form that is bioactive against yeast and other microorganisms. In this study, we use multiphoton microscopy (MPM) and fluorescence lifetime imaging microscopy (FLIM) to characterise ZnPT formulations and map the delivery of particles into follicles within human skin. To simulate real-world conditions, it was applied using a massage or no-massage technique, while simultaneously assessing the dissolution using Zinpyr-1, a zinc labile fluorescent probe. Read More

View Article and Full-Text PDF

Investigation of the relationship between seborrheic dermatitis and metabolic syndrome parameters.

J Cosmet Dermatol 2022 May 27. Epub 2022 May 27.

Department of Dermatology, Ankara City Hospital, Ankara, Turkey.

Background: Seborrheic dermatitis (SD) is a common, chronic inflammatory disease with relapses and remissions.

Objectives: So we planned to investigate the relationship between SD and metabolic syndrome (Mets).

Methods: 54 patients over 18 years of age without known diabetes mellitus, hypertension, coronary artery disease who were clinically diagnosed with SD in our clinic and 47 healthy controls were included in the study. Read More

View Article and Full-Text PDF

Topical ruxolitinib in the treatment of refractory facial seborrheic dermatitis.

JAAD Case Rep 2022 Jun 23;24:59-60. Epub 2022 Apr 23.

Department of Dermatology, University of Rochester Medical Center, Rochester, New York.

View Article and Full-Text PDF

Extensive eczema herpeticum in a previously well child.

Int J Emerg Med 2022 May 21;15(1):21. Epub 2022 May 21.

Department of Pediatrics, Salmaniya Medical Complex, Manama, Bahrain.

Background: Eczema herpeticum, also known as Kaposi varicelliform eruption, is a potentially life-threatening disseminated cutaneous viral infection. In the majority of cases, this condition develops as a complication in patients with atopic dermatitis. However, it may arise in a wide spectrum of pre-existing skin conditions, including psoriasis, seborrheic dermatitis, contact dermatitis, cutaneous T cell lymphoma, pemphigus vulgaris, and others. Read More

View Article and Full-Text PDF

Tanshinone Capsules Combined With Prednisone for Facial Seborrheic Dermatitis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.

Front Med (Lausanne) 2022 29;9:816419. Epub 2022 Apr 29.

College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing, China.

Background: Facial seborrheic dermatitis (FSD), also called facial seborrheic eczema, is a common disease affecting both male and female patients worldwide. Tanshinone is the main bioactive component extracted from the Traditional Chinese Medicine , which is widely used in treating skin inflammatory diseases. It is necessary to evaluate the clinical evidence for tanshinone capsule treatment of FSD. Read More

View Article and Full-Text PDF

Prevalence and Pattern of Paediatric dermatoses among children in Aminu Kano teaching Hospital Kano, Nigeria.

Authors:
Aishatu Yahya

Acta Biomed 2022 05 11;93(2):e2022037. Epub 2022 May 11.

a:1:{s:5:"en_US";s:34:"Yusuf Maitama Sule University Kano";}.

Introduction: Skin disorders are common among children, most especially the infections and infestations as the immunity is not fully developed during childhood. Skin disorders are among common causes of morbidity in developing countries of Sub-Saharan Africa.Skin disorders are major cause of concern among children. Read More

View Article and Full-Text PDF

Is the Frequency of Seborrheic Dermatitis Related to Climate Parameters?

Sisli Etfal Hastan Tip Bul 2022 28;56(1):91-95. Epub 2022 Mar 28.

Department of Dermatology, Haseki Training and Research Hospital, Istanbul, Turkey.

Objectives: The aim of this study was to determine the frequency of seborrheic dermatitis (SD) by months and seasons in Istanbul, Turkey, and to examine the relationships between SD frequency and meteorological data, such as average temperature (°C), average humidity (%), average sunshine duration, and solar radiation per months.

Methods: The study was conducted at Dermatology Department of Haseki Training and Research Hospital. The data of all adult patients who applied to the dermatology outpatient clinic between June 2018 and May 2020 were obtained. Read More

View Article and Full-Text PDF

Mean platelet volume may not be a marker of inflammation in patients with seborrheic dermatitis.

J Cosmet Dermatol 2022 May 5. Epub 2022 May 5.

University of Health Sciences, Ankara Ataturk Sanatoryum Training and Research Hospital, Department of Internal Medicine, Ankara, Turkey.

View Article and Full-Text PDF

The change in the frequency and severity of facial dermatoses and complaints in healthcare workers during the COVID-19.

J Cosmet Dermatol 2022 May 4. Epub 2022 May 4.

Department of Dermatology, Education and Research Hospital, Sakarya University, Sakarya, Turkey.

Background: The coronavirus disease 2019 (COVID-19) pandemic has led to a dramatic increase in the use of personal protective equipment (PPE). However, the increased use of PPEs may lead to facial skin complaints.

Aims: This survey study aims to evaluate the effect of the COVID-19 pandemic on facial dermatoses and complaints. Read More

View Article and Full-Text PDF

Effectiveness of FastFung agar in the isolation of Malassezia furfur from skin samples.

Mycoses 2022 Jul 25;65(7):704-708. Epub 2022 May 25.

Department of Medical Microbiology, Medical Faculty, Cukurova University, Adana, Turkey.

Background: Lipophilic basidiomycetous yeasts of the Malassezia genus can cause various skin diseases, such as seborrheic dermatitis, pityriasis versicolor, folliculitis and atopic dermatitis, and even life-threatening fungemia in newborns and immunocompromised individuals. Routine mycological media used in clinical practice do not contain sufficient lipid ingredients required for the growth of Malassezia species. A recently developed medium, FastFung agar, is promising for culturing fastidious fungal species. Read More

View Article and Full-Text PDF

Global Burden, Incidence and Disability-Adjusted Life-Years for Dermatitis: A Systematic Analysis Combined With Socioeconomic Development Status, 1990-2019.

Front Cell Infect Microbiol 2022 12;12:861053. Epub 2022 Apr 12.

Department of Burns and Plastic and Wound Repair Surgery, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.

Background: Dermatitis is an important global health problem that not only affects social interaction and physical and mental health but also causes economic burden. Health problems or distress caused by dermatitis may be easily overlooked, and relevant epidemiological data are limited. Therefore, a better understanding of the burden of dermatitis is necessary for developing global intervention strategies. Read More

View Article and Full-Text PDF

L. Leaf Extracts and Their Metabolites Inhibit the Aryl Hydrocarbon Receptor (AhR) Activation In Vitro and in Human Keratinocytes: Potential Impact on Inflammatory Skin Diseases and Skin Cancer.

Molecules 2022 Apr 13;27(8). Epub 2022 Apr 13.

Laboratory of Pharmacognosy and Chemistry of Natural Products, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece.

Aryl hydrocarbon receptor (AhR) activation by environmental agents and microbial metabolites is potentially implicated in a series of skin diseases. Hence, it would be very important to identify natural compounds that could inhibit the AhR activation by ligands of microbial origin as 6-formylindolo[3,2-b]carbazole (FICZ), indirubin (IND) and pityriazepin (PZ) or the prototype ligand 2,3,7,8-tetrachlorodibenzo--dioxin (TCDD). Five different dry L. Read More

View Article and Full-Text PDF

Immune regulation in polycystic ovary syndrome.

Clin Chim Acta 2022 Jun 18;531:265-272. Epub 2022 Apr 18.

Department of Central Laboratory, Beijing Obstetrics and Gynecology Hospital, Capital Medical University. Beijing Maternal and Child Health Care Hospital. Beijing 100026, China. Electronic address:

A polycystic ovarian syndrome (PCOS) is the most common endocrine disorder affecting females. Furthermore, it is a heterogeneous disease with a variety of etiologies and outcomes. Patients frequently complain about infertility, irregular menstruation, acne, seborrheic dermatitis, hirsutism, and obesity. Read More

View Article and Full-Text PDF

Investigation of the relationship between inflammatory blood parameters and seborrheic dermatitis.

J Cosmet Dermatol 2022 Apr 11. Epub 2022 Apr 11.

Dermatology Department, Medicine Faculty, Sivas Cumhuriyet University, Sivas, Turkey.

Objective: Seborrheic dermatitis (SD) is a chronic inflammatory disease. The etiology of the disease is still unknown. The systemic immune-inflammation index (SII), red cell distribution width (RDW), mean platelet volume (MPV), C-reactive protein (CRP), monocyte to HDL cholesterol ratio (MHR), platelet to lymphocyte ratio (PLR), and neutrophil to lymphocyte ratio (NLR) have all been reported as inflammatory markers in recent studies. Read More

View Article and Full-Text PDF

Seborrheic Dermatitis in Older Adults: Pathogenesis and Treatment Options.

Drugs Aging 2022 05 8;39(5):315-321. Epub 2022 Apr 8.

Department of Dermatology, University of Alabama at Birmingham, 1720 University Blvd, Suite 500, Birmingham, AL, 35294, USA.

Seborrheic dermatitis is a common and chronic skin disease, which is particularly prevalent in older adults. While a specific cause of seborrheic dermatitis remains largely unelucidated, the currently understood pathogenesis of seborrheic dermatitis revolves around the presence of Malassezia yeast colonies and an inflammatory response in the affected individual. Keratinocyte proliferation resulting from inflammasome response in the host skin leads to the clinically relevant symptoms of seborrheic dermatitis. Read More

View Article and Full-Text PDF