1,771 results match your criteria Sebaceous Gland Carcinoma


Sebaceous carcinoma of the lip: a case report and review of the literature.

J Med Case Rep 2022 Jun 18;16(1):241. Epub 2022 Jun 18.

Department of Clinical and Experimental Medicine, University of Foggia, Via Carelli 28, 71100, Foggia, Italy.

Background: Sebaceous carcinoma is a very rare, aggressive, malignant tumor arising in the adnexal epithelium of the sebaceous gland. Sebaceous carcinoma in the oral cavity is extremely rare, with only 14 cases reported in literature. We reported the fourth case of sebaceous carcinoma involving the lip CASE PRESENTATION: A 71-year-old Caucasian male smoker presented an ulcerated lesion in the lateral region of the lower lip. Read More

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Sebaceous Adenocarcinoma in Parotid Gland of a 65-Year-Old.

S D Med 2022 Apr;75(4):158-160

University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.

Sebaceous adenocarcinoma of the parotid gland is a rare, malignant epithelial neoplasm with focal areas of sebaceous differentiation. A literature search revealed only 34 cases as of December 2020. Our case brings this total to 35. Read More

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Epidemiological characteristics of malignant eyelid tumors at a referral hospital in Japan.

Jpn J Ophthalmol 2022 Jul 7;66(4):343-349. Epub 2022 Jun 7.

Department of Ophthalmology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.

Purpose: To clarify the incidence and demographic characteristics of malignant eyelid tumors diagnosed in a single institute in Japan.

Study Design: Retrospective, observational case series METHODS: Patients with malignant eyelid tumors diagnosed histopathologically at Tokyo Medical University Hospital between 1995 and 2019 were reviewed retrospectively. The incidence and demographic profile of malignant eyelid tumors were analyzed. Read More

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Clinical and histopathological profile of primary caruncular lesions.

Indian J Ophthalmol 2022 Jun;70(6):1975-1981

Department of Ocular Pathology, Larson and Tourbo, Vision Research Foundation, Chennai, Tamil Nadu, India.

Purpose: To provide a retrospective analysis of lesions of the caruncle which have been very rarely reported in the literature.

Methods: A retrospective review of all the caruncular lesions between January 2000 and January 2020 was done at a single tertiary eye care hospital. The lesions were classified as benign and malignant lesions. Read More

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Unique orbital biphenotypic tumour with neuroendocrine and sebaceous carcinoma features.

Orbit 2022 May 29:1-4. Epub 2022 May 29.

Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, USA.

A 60-year-old female presented with a large, left upper eyelid mass that had rapidly expanded in the 3 months prior to presentation. She had a presumed chalazion excised from the same area 1.5 years ago, but no pathology was investigated. Read More

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Non-sebaceous lymphadenoma-like mucoepidermoid carcinoma: A case report.

Pathol Int 2022 May 21. Epub 2022 May 21.

Center of Oral Clinical Examination, Hiroshima University Hospital, Hiroshima, Japan.

Non-sebaceous lymphadenoma is a rare benign salivary gland tumor comprised of non-sebaceous epithelial cells and lymphoid tissue. Although its clinicopathological features have been described, its histogenesis and genetic background have not yet been elucidated. MAML2 rearrangement and the resultant CRTC1/3-MAML2 fusion gene are well-known specific genetic changes in mucoepidermoid carcinoma. Read More

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Metastases to the Parotid Gland: Study from a Tertiary Care Centre.

Head Neck Pathol 2022 May 16. Epub 2022 May 16.

Department of Radiation Oncology, BRA Institute Rotary Cancer Hospital and National Cancer Institute, All India Institute of Medical Sciences, New Delhi, 110029, India.

Background: Metastases account for 6-25% of parotid tumors, often presenting dilemmas in their diagnosis.

Methods: Parotid metastases diagnosed on histology/cytology were retrieved. MUC2, MUC5AC, androgen receptor immunohistochemistry was performed in select cases. Read More

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Incidence and trends of cutaneous adnexal tumors in the United States in 2000-2018: A population-based study.

J Am Acad Dermatol 2022 May 4. Epub 2022 May 4.

Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia; Winship Cancer Institute of Emory University School of Medicine, Atlanta, Georgia; Atlanta VA Health Care System, Decatur, Georgia. Electronic address:

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Sebaceous breast carcinoma.

Autops Case Rep 2022 14;12:e2021365. Epub 2022 Apr 14.

Universidade Federal do Maranhão (UFMA), Hospital Universitário, São Luís, MA, Brasil.

Breast sebaceous carcinoma is one of the rarest breast neoplasms, with less than 30 cases reported worldwide. Due to the rarity, the new WHO classification of breast tumors grouped these tumors among the ductal carcinoma. A detailed description of these cases is relevant due to the insufficient knowledge about the prognosis of this neoplasm. Read More

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Epithelial-myoepithelial carcinoma ex pleomorphic adenoma of the parotid gland with unique histologic differentiation: A rare case report.

J Oral Maxillofac Pathol 2022 Feb 28;26(Suppl 1):S34-S39. Epub 2022 Feb 28.

Oral Medicine and Radiology, Dental College, Regional Institute of Medical Sciences, Imphal, Manipur, India.

Epithelial myoepithelial carcinoma (EMC) is an uncommon low-to-intermediate grade salivary gland malignancy that accounts for 1% of all tumors arising in salivary glands. About 80% of these tumors affect the parotid gland. These lesions either arise or from existing pleomorphic adenoma (PA). Read More

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February 2022

A Case of Apocrine Carcinoma Arising in a Sebaceous Naevus: Detection of HRAS G13R Mutation.

Acta Derm Venereol 2022 04 13;102:adv00697. Epub 2022 Apr 13.

Department of Dermatology, Shinshu University School of Medicine. 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan.

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Rare Cutaneous Malignancies in Skin of Color.

Dermatol Surg 2022 Jun 6;48(6):606-612. Epub 2022 Apr 6.

Department of Dermatology, University of Nebraska Medical Center, Omaha, Nebraska.

Background: There is a scarcity of information regarding the clinical characteristics of rare cutaneous malignancies in skin of color that has yet to be comprehensively explored.

Objective: To review and compile the racial differences in epidemiology, clinical presentation, histology, treatments, and outcomes of 3 rare skin cancers: dermatofibrosarcoma protuberans (DFSP), Merkel cell carcinoma (MCC), and sebaceous carcinoma (SC).

Methods: Several searches with keywords denoting specific skin cancer type and race were conducted on PubMed to complete this narrative review. Read More

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Sebaceous gland carcinoma: analysis based on the 8 edition of American Joint Cancer Committee classification.

Eye (Lond) 2022 Mar 26. Epub 2022 Mar 26.

Operation Eyesight Universal Institute for Eye Cancer, L V Prasad Eye Institute, Hyderabad, India.

Purpose: To assess the prognostic value of T category of the 8 edition of American Joint Committee on Cancer (AJCC) classification in periocular sebaceous gland carcinoma (SGC).

Methods: Retrospective interventional case series of 119 cases.

Results: Based on the T category of 8th edition of AJCC classification, 119 periocular SGCs were classified into T1 (n = 33, 28%), T2 (n = 37, 31%) T3 (n = 17, 14%) and T4 (n = 32, 27%). Read More

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Giant sebaceous nevus occupying half of the head associated with sebaceous carcinoma, apocrine adenocarcinoma, and basal cell carcinoma: A case report.

JPRAS Open 2022 Jun 10;32:88-92. Epub 2022 Mar 10.

Department of Plastic and Reconstructive Surgery, Kansai Medical University, Osaka, Japan.

We herein report a 57-year-old man afflicted with multiple malignant tumors arising from a giant sebaceous nevus on his left parieto-temporal scalp and neck. The upper eyelid was resected in all layers, and the auricle was resected as well, leaving part of the external auricular cartilage; the parotid gland area was also resected over the parotid fascia. The lost part of the left eyebrow was reconstructed using an anterior forehead skin flap, and the residual defect was covered with skin graft and expanded scalp flap. Read More

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Impaired Wnt/beta-catenin and protein patched homolog 1 signaling in extraocular sebaceous carcinoma: A clinical and histopathological study.

J Dermatol 2022 Jun 22;49(6):600-606. Epub 2022 Mar 22.

Department of Dermatology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

Sebaceous carcinoma (SC) is a rare malignant neoplasm with sebaceous differentiation. SC is classified into eyelid and extraocular SC clinically. Most studies have focused on the eyelid SC in terms of pathogenesis, treatment, and prognosis. Read More

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Sebaceous Carcinoma of the Vulva: An Unexpected Diagnosis and Literature Review.

Acta Med Port 2022 Jan 3;35(1):63-67. Epub 2022 Jan 3.

Serviço de Ginecologia. Instituto Português de Oncologia de Coimbra. Coimbra. Portugal.

Sebaceous carcinoma of the vulva is a rare malignancy of the sebaceous glands, with potentially aggressive behaviour, that is usually found in the peri-ocular area. Nonetheless, there are sebaceous glands in the vulva and this diagnosis is especially rare, with only ten cases described in the literature. We report a case of 78-year-old female patient who presented with vulvar pruritus, previously treated with topical steroid and antifungal treatments, without improvement. Read More

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January 2022

Clinicopathological Analysis and Surgical Outcome of Eyelid Malignancies: A Study of 332 Cases.

J Skin Cancer 2022 18;2022:4075668. Epub 2022 Feb 18.

Department of Pathology, Northern International Medical College, Dhaka, Bangladesh.

Background: Eyelid tumours are common in our ophthalmic practice. Malignancy cases account only for one-fourth of all eyelid tumours. The most aggressive eyelid malignancy is sebaceous gland carcinoma, but its occurrences are rare in western countries. Read More

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February 2022

Title: Clinico-pathological and survival profiles of orbito-ocular tumors in Enugu Nigeria. Is there an emerging trend?

Rare Tumors 2022 23;14:20363613221079763. Epub 2022 Feb 23.

Neurosurgery Unit, Department of Surgery, University of Nigeria Teaching Hospital Ituku/Ozalla Enugu, Enugu, Nigeria.

Background: Orbito-ocular tumors are rare, but they cause significant morbidity and mortality. There are reported variations in their pattern of presentation and frequency of occurrence.

Objective: To evaluate the occurrence, clinico-pathologic spectrum, and patterns of orbito-ocular neoplasms as well as the treatment and outcome profiles. Read More

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February 2022

TROP2 Expression in Sebaceous and Sweat Gland Carcinoma.

J Clin Med 2022 Jan 25;11(3). Epub 2022 Jan 25.

Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.

Sebaceous carcinoma and sweat gland carcinoma (malignant tumors with apocrine and eccrine differentiation) are rare malignant skin adnexal tumors that differentiate toward sebaceous gland and eccrine and apocrine glands, respectively. Owing to the rarity of these carcinomas, standard treatments for advanced disease have not been established. Because the prognosis of patients with systemic metastasis is poor, a new treatment for these diseases is eagerly desired. Read More

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January 2022

Impact of expert pathology review in skin adnexal carcinoma diagnosis: Analysis of 2573 patients from the French CARADERM network.

Eur J Cancer 2022 03 30;163:211-221. Epub 2022 Jan 30.

Dermatology and Dermatopathology, University Hospital and Faculty of Medicine, University of Strasbourg, France.

Purpose: To prospectively assess the impact of expert pathological review of skin adnexal carcinoma diagnosis in France.

Methods: From 2014 to 2019, 2573 samples from patients with newly diagnosed or suspected skin adnexal carcinomas were reviewed prospectively by expert pathologists through the national CARADERM (CAncers RAres DERMatologiques) network. Changes in diagnosis between referral and expert review were analysed regarding their potential impact on patient care or prognosis. Read More

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The effect of direct cell injury inflicted by cryotherapy on eyelid sebaceous gland carcinoma cells: An ex-vivo experimental study.

Indian J Ophthalmol 2022 Feb;70(2):630-633

Larson and Turbo Department of Ocular Pathology, Vision Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India.

Purpose: To evaluate the effect of direct cell injury of cryotherapy on eyelid sebaceous gland carcinoma cells by an ex vivo cryotherapy experiment.

Methods: It was a prospective interventional case series. Six patients with biopsy-proven nodular sebaceous gland carcinoma were included. Read More

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February 2022

Extraocular sebaceous carcinoma: tumor presentation of rapid evolution.

An Bras Dermatol 2022 Mar-Apr;97(2):268-271. Epub 2022 Jan 15.

Faculdade de Medicina, Universidade Estadual Paulista, Botucatu, SP, Brazil. Electronic address:

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Clinical time course of the neglected giant sebaceous gland carcinoma.

Rom J Ophthalmol 2021 Jul-Sep;65(3):290-292

Department of Ophthalmology, Sakarya University Education and Research Hospital, Sakarya, Turkey.

In this report, we discussed the progression from the initial presentation until surgical intervention, clinical course, and devastating outcome of a neglected giant sebaceous gland carcinoma of the eyelid in a poorly compliant elderly patient. A 79-year-old woman was referred for treatment of a giant ulcero-nodular lesion in the right upper eyelid. Nine months before, an orange lesion arising from the tarsal conjunctiva in the upper eyelid was observed in her examination undergone in the healthcare center where she initially presented, and the cornea appeared transparent. Read More

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January 2022

Sebaceous Lymphadenoma of Parotid: Case Report of a Rare Entity.

Indian J Surg Oncol 2021 Dec 13;12(Suppl 2):351-354. Epub 2021 Jun 13.

Ruby Hall Clinic, 40, Sassoon Road, Pune, 411001 India.

Sebaceous differentiation can be normally seen in salivary glands. An entity first described by Hamperi. Sebaceous components are present in several salivary gland tumors like Warthin's tumor and mucoepidermoid tumor. Read More

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December 2021

Eyelid Tumours in Northern Malaysia: A Five-Year Review.

Cureus 2022 Jan 4;14(1):e20922. Epub 2022 Jan 4.

Ophthalmology, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, MYS.

Background The majority of eyelid tumours are benign in nature and constitute 82%-98% of all eyelid tumours. This study aimed to explore the prevalence and frequency of histopathological diagnoses of eyelid tumours encountered in Hospital Sultanah Bahiyah (HSB), Malaysia, from 2016 to 2020. Method This study is a case series of 136 patients with eyelid tumours who underwent eyelid biopsy. Read More

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January 2022

Outcome after treatment for sebaceous carcinoma: A multicenter study.

J Surg Oncol 2022 Mar 6;125(4):730-735. Epub 2022 Jan 6.

Department of Surgical Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.

Background: Sebaceous carcinoma (SC) is a rare malignant tumour whereby, comprehensive long-term data are scarce. This study aimed to assess the outcome of patients treated with resection for SC.

Methods: Patients treated at four tertiary centres were included. Read More

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The spectrum and clinicopathological correlation of eyelid lesions: Twenty years' experience at a tertiary eye care center in South India.

Indian J Ophthalmol 2022 Jan;70(1):43-50

Orbit, Oculoplasty, Reconstructive and Aesthetic Services, Sankara Nethralaya, Medical Research Foundation, Chennai, Tamil Nadu, India.

Purpose: : To study the epidemiological pattern and diagnostic accuracy of histopathologically proven eyelid lesions over a period of two decades.

Methods: : A retrospective study of all histopathologically proven eyelid lesions from April 1996 to March 2016 was conducted. The lesions were broadly categorized as benign or malignant. Read More

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January 2022

Ocular and periocular tumors in 855 Asian Indian geriatric patients.

Oman J Ophthalmol 2021 Sep-Dec;14(3):153-156. Epub 2021 Oct 20.

Department of Eyesmart EMR and AEye (AVD), LV Prasad Eye Institute, Hyderabad, Telangana, India.

Objective: The objective of this study was to describe the eye tumors in Asian Indian geriatric population (age >60 years) presenting to a multitier ophthalmology hospital network in India.

Methods: This was a retrospective study of 855 Asian Indian geriatric patients.

Results: During the 3-year study period, 855 geriatric patients were diagnosed with eye tumors. Read More

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October 2021

The prevalence of various eyelid skin lesions in a single-centre observation study.

Postepy Dermatol Alergol 2021 Oct 8;38(5):804-807. Epub 2020 Jun 8.

Ocular Oncology Service, Department of Ophthalmology, Poznan University of Medical Sciences, Poznan, Poland.

Introduction: The role of the eyelids is to protect and moisturise the eye. Despite its small relative surface area, 5-10% of skin cancers originate in the eyelids.

Aim: To assess the prevalence of different types of skin lesions in the area of eyelids based on retrospective histopathology data from a tertiary centre. Read More

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October 2021

Expression and Significance of AQP3 in Cutaneous Lesions.

Anal Cell Pathol (Amst) 2021 26;2021:7866471. Epub 2021 Oct 26.

Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Pathology, Peking University Cancer Hospital & Institute, Beijing, China.

Aquaporin 3 (AQP3) is the membrane channel of water and involved in fluid homeostasis. The aim of this study was to reveal the expression and significance of AQP3 in cutaneous lesions. We analyzed AQP3 mRNA levels using RT-PCR in 311 cutaneous lesions and confirmed AQP3 expression in these lesions by immunohistochemistry. Read More

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