2,468 results match your criteria Sebaceous Carcinoma

Eyelid sebaceous gland carcinoma, validation of AJCC 8th edition T staging- a retrospective study from North India.

Acta Ophthalmol 2022 Jun 24. Epub 2022 Jun 24.

Department of Molecular Medicine & Biotechnology, Sanjay Gandhi Post Graduate Institute of Medical Science (SGPGIMS), Lucknow, Uttar Pradesh, India.

Purpose: This study compares the 8th edition staging of AJCC for prognosis of eyelid Sebaceous Gland Carcinoma (SGC) patients with respect to the 7th edition.

Methods: A retrospective study was undertaken over a period of 100 months. Ninety-nine histopathologically proven cases of eyelid SGC available for follow-up were recruited. Read More

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Malignant lesions of the caruncle.

Eye (Lond) 2022 Jun 21. Epub 2022 Jun 21.

The Sussex Eye Hospital, Brighton and Sussex University Hospitals NHS Trust, Brighton, UK.

Caruncle malignancy is rare, but signs of disease can be easily missed by both patients and clinicians. There is significant potential for significant morbidity and even mortality from delayed diagnosis and treatment. Clinical features of primary malignant cancer include rapid growth, pigment deposition, ulcerated surface and bleeding. Read More

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Sebaceous carcinoma of the lip: a case report and review of the literature.

J Med Case Rep 2022 Jun 18;16(1):241. Epub 2022 Jun 18.

Department of Clinical and Experimental Medicine, University of Foggia, Via Carelli 28, 71100, Foggia, Italy.

Background: Sebaceous carcinoma is a very rare, aggressive, malignant tumor arising in the adnexal epithelium of the sebaceous gland. Sebaceous carcinoma in the oral cavity is extremely rare, with only 14 cases reported in literature. We reported the fourth case of sebaceous carcinoma involving the lip CASE PRESENTATION: A 71-year-old Caucasian male smoker presented an ulcerated lesion in the lateral region of the lower lip. Read More

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Sebaceous carcinoma of trunk with bilateral axillary lymph node metastasis: a rare presentation of malignant adnexal tumor in young adult.

J Surg Case Rep 2022 Jun 14;2022(6):rjac280. Epub 2022 Jun 14.

Department of Pathology, B.P. Koirala Institute of Health Sciences, Dharan, Nepal.

Malignant adnexal tumors of skin are rare. Sebaceous carcinoma-a rare and aggressive cutaneous tumor-is frequently located in the periorbital region. Malignant adnexal tumors of sebaceous carcinoma type on trunk with axillary lymph node and distant metastasis in young adult is rare. Read More

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Sebaceous Adenocarcinoma in Parotid Gland of a 65-Year-Old.

S D Med 2022 Apr;75(4):158-160

University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.

Sebaceous adenocarcinoma of the parotid gland is a rare, malignant epithelial neoplasm with focal areas of sebaceous differentiation. A literature search revealed only 34 cases as of December 2020. Our case brings this total to 35. Read More

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Epidemiological characteristics of malignant eyelid tumors at a referral hospital in Japan.

Jpn J Ophthalmol 2022 Jul 7;66(4):343-349. Epub 2022 Jun 7.

Department of Ophthalmology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.

Purpose: To clarify the incidence and demographic characteristics of malignant eyelid tumors diagnosed in a single institute in Japan.

Study Design: Retrospective, observational case series METHODS: Patients with malignant eyelid tumors diagnosed histopathologically at Tokyo Medical University Hospital between 1995 and 2019 were reviewed retrospectively. The incidence and demographic profile of malignant eyelid tumors were analyzed. Read More

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Primary or metastatic lung cancer? Sebaceous carcinoma of the thigh: A case report.

World J Clin Cases 2022 May;10(14):4586-4593

Department of Respiratory and Critical Care Medicine, The Affiliated Hospital of Chengdu University School of Clinical Medicine, Chengdu University, Chengdu 610081, Sichuan Province, China.

Background: Sebaceous carcinoma (SC), a malignancy primarily characterized by aggressive growth, affects cutaneous tissues of the periocular region. Extraocular SC is extremely rare, especially in the extremities, as evidenced by only a handful of reported cases.

Case Summary: A 65-year-old man presented with a rapidly enlarging swelling on the left inner thigh, which was initially misdiagnosed as a subcutaneous abscess. Read More

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Clinical and histopathological profile of primary caruncular lesions.

Indian J Ophthalmol 2022 Jun;70(6):1975-1981

Department of Ocular Pathology, Larson and Tourbo, Vision Research Foundation, Chennai, Tamil Nadu, India.

Purpose: To provide a retrospective analysis of lesions of the caruncle which have been very rarely reported in the literature.

Methods: A retrospective review of all the caruncular lesions between January 2000 and January 2020 was done at a single tertiary eye care hospital. The lesions were classified as benign and malignant lesions. Read More

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PRAME immunostain expression in sebaceous lesions, cutaneous carcinomas and adnexal structures.

Pathology 2022 May 26. Epub 2022 May 26.

Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong.

The use of immunostain for PRAME antigen is well established for cutaneous melanolocytic lesions. However, its staining in other cutaneous structures and lesions is under reported. This study assessed PRAME staining in a large cohort of normal skin tissue, sebaceous lesions, and cutaneous carcinomas to better delineate patterns of PRAME immunoreactivity. Read More

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Expression profile of CD10, BCL-2, p63, and EMA in the normal skin and basal cell carcinomas: an immunohistochemical reappraisal.

Actas Dermosifiliogr 2022 May 27. Epub 2022 May 27.

Department of Pathology, Assiut University, Assiut, Egypt.

Background: Basal cell carcinoma (BCC) is common cutaneous malignancy.

Aims: To examine the expression patterns of CD10, p63, BCL-2, and epithelial membrane antigen (EMA) proteins in BCC.

Materials And Methods: We used immunohistochemistry to evaluate the expression pattern of these proteins in 45 BCC specimens and their adjacent normal skin. Read More

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Unique orbital biphenotypic tumour with neuroendocrine and sebaceous carcinoma features.

Orbit 2022 May 29:1-4. Epub 2022 May 29.

Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, USA.

A 60-year-old female presented with a large, left upper eyelid mass that had rapidly expanded in the 3 months prior to presentation. She had a presumed chalazion excised from the same area 1.5 years ago, but no pathology was investigated. Read More

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Sebaceous adenoma occurring within an intracranial dermoid cyst.

Neuropathology 2022 May 25. Epub 2022 May 25.

Department of Neurosurgery, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.

Among intracranial cystic lesions, dermoid cysts and epidermoid cysts are relatively common benign tumors. In a small number of these tumors, it is known that squamous cell carcinomas arise in the lining epithelium of the cysts. Among tumors derived from the appendage, only one case of hidradenoma within a dermoid cyst and no cases of sebaceous tumor have been reported previously. Read More

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Merkel cell carcinoma of the eyelid and periocular region: A review.

Noreen M Walsh

Saudi J Ophthalmol 2021 Jul-Sep;35(3):186-192. Epub 2022 Apr 18.

Department of Pathology, Queen Elizabeth II Health Sciences Center, Nova Scotia Health Authority (Central Zone), Halifax, Canada.

Merkel cell carcinoma (MCC) is a rare primary cutaneous neuroendocrine carcinoma with a high mortality rate. It typically affects elderly Caucasians, with a slight predilection for males. It is associated with chronic sun exposure and/or immunosuppression. Read More

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Non-sebaceous lymphadenoma-like mucoepidermoid carcinoma: A case report.

Pathol Int 2022 May 21. Epub 2022 May 21.

Center of Oral Clinical Examination, Hiroshima University Hospital, Hiroshima, Japan.

Non-sebaceous lymphadenoma is a rare benign salivary gland tumor comprised of non-sebaceous epithelial cells and lymphoid tissue. Although its clinicopathological features have been described, its histogenesis and genetic background have not yet been elucidated. MAML2 rearrangement and the resultant CRTC1/3-MAML2 fusion gene are well-known specific genetic changes in mucoepidermoid carcinoma. Read More

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Metastases to the Parotid Gland: Study from a Tertiary Care Centre.

Head Neck Pathol 2022 May 16. Epub 2022 May 16.

Department of Radiation Oncology, BRA Institute Rotary Cancer Hospital and National Cancer Institute, All India Institute of Medical Sciences, New Delhi, 110029, India.

Background: Metastases account for 6-25% of parotid tumors, often presenting dilemmas in their diagnosis.

Methods: Parotid metastases diagnosed on histology/cytology were retrieved. MUC2, MUC5AC, androgen receptor immunohistochemistry was performed in select cases. Read More

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Invasive Lobular Carcinoma Arising in Ectopic Breast Tissue: A Case Report.

Cureus 2022 Apr 12;14(4):e24055. Epub 2022 Apr 12.

Pathology, Centro Hospitalar de Entre Douro e Vouga, Santa Maria da Feira, PRT.

Incomplete regression of the embryonic mammary line occurs in 0.3-6% of the population. Ectopic breast tissue is mostly asymptomatic and can undergo malignant transformation. Read More

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Rare malignant adnexal tumour of the skin involving distal phalanx of right thumb with co-existing primary lung cancer in a 72-year-old patient: A case report.

Int J Surg Case Rep 2022 Jun 10;95:107174. Epub 2022 May 10.

Department of General Surgery, Mata Chanan Devi Hospital, New Delhi, India.

Introduction And Importance: Malignant adnexal tumours of the skin are a group of rare malignancies. These tumours can further differentiate into eccrine, apocrine, sebaceous, sweat duct, or ceruminous glands within the skin or follicular cells. Sebaceous carcinoma, a malignant adnexal tumour of the skin, is a rare and malignant tumour of the sebaceous glands. Read More

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miR-196b-5p and miR-107 Expression Differentiates Ocular Sebaceous Carcinoma from Squamous Cell Carcinoma of the Conjunctiva.

Int J Mol Sci 2022 Apr 28;23(9). Epub 2022 Apr 28.

Rotterdam Eye Hospital, Schiedamse Vest 180, 3011 BH Rotterdam, The Netherlands.

An Ocular Sebaceous Carcinoma (OSC) is a rare malignant tumor for which initial clinical and pathological diagnosis is often incorrect. OSCs can mimic Squamous Cell Carcinomas of the Conjunctiva (SCCC). The aim of this study was to find microRNA biomarkers to distinguish OSCs and SCCCs from normal tissue and from each other. Read More

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Dermoscopy of cutaneous adnexal tumours: a systematic review of the literature.

J Eur Acad Dermatol Venereol 2022 May 10. Epub 2022 May 10.

Centro Oncologico ad Alta Tecnologia Diagnostica, Azienda Unità Sanitaria Locale - IRCCS di Reggio Emilia, Reggio Emilia, Italy.

Cutaneous adnexal tumours (ATs) encompass a variegated group of hamartomas and benign or malignant tumours, originating from the hair follicle, sebaceous, eccrine or apocrine glands that may simulate other cutaneous neoplasms. This study aims to provide a comprehensive overview of the spectrum of clinical and dermoscopic features of ATs, to better define these lesions and assist in the differential diagnosis. We performed a two-step systematic search of the literature in PubMed, Embase and Cochrane Library databases from inception until 4 September 2020. Read More

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Incidence and trends of cutaneous adnexal tumors in the United States in 2000-2018: A population-based study.

J Am Acad Dermatol 2022 May 4. Epub 2022 May 4.

Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia; Winship Cancer Institute of Emory University School of Medicine, Atlanta, Georgia; Atlanta VA Health Care System, Decatur, Georgia. Electronic address:

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Sebaceous breast carcinoma.

Autops Case Rep 2022 14;12:e2021365. Epub 2022 Apr 14.

Universidade Federal do Maranhão (UFMA), Hospital Universitário, São Luís, MA, Brasil.

Breast sebaceous carcinoma is one of the rarest breast neoplasms, with less than 30 cases reported worldwide. Due to the rarity, the new WHO classification of breast tumors grouped these tumors among the ductal carcinoma. A detailed description of these cases is relevant due to the insufficient knowledge about the prognosis of this neoplasm. Read More

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Epithelial-myoepithelial carcinoma ex pleomorphic adenoma of the parotid gland with unique histologic differentiation: A rare case report.

J Oral Maxillofac Pathol 2022 Feb 28;26(Suppl 1):S34-S39. Epub 2022 Feb 28.

Oral Medicine and Radiology, Dental College, Regional Institute of Medical Sciences, Imphal, Manipur, India.

Epithelial myoepithelial carcinoma (EMC) is an uncommon low-to-intermediate grade salivary gland malignancy that accounts for 1% of all tumors arising in salivary glands. About 80% of these tumors affect the parotid gland. These lesions either arise or from existing pleomorphic adenoma (PA). Read More

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February 2022

Left Buttock Sebaceus Carcinoma: A Case Report and Review of the Literature.

Curr Health Sci J 2021 Oct-Dec;47(4):595-601. Epub 2021 Dec 31.

Department of Plastic and Reconstructive Surgery, University of Medicine and Pharmacy of Craiova, Romania.

Sebaceous carcinoma is a rare, aggressive, malignant tumour, characterized by a tendency for local recurrence and distant metastases. This case report presents a rare form of sebaceous carcinoma in an 86 years-old female. Clinical examination revealed a 12cm nodular tumour, yellow-brown in colour, located on the left buttock of the patient. Read More

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December 2021

A Case of Apocrine Carcinoma Arising in a Sebaceous Naevus: Detection of HRAS G13R Mutation.

Acta Derm Venereol 2022 04 13;102:adv00697. Epub 2022 Apr 13.

Department of Dermatology, Shinshu University School of Medicine. 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan.

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Rare Cutaneous Malignancies in Skin of Color.

Dermatol Surg 2022 Jun 6;48(6):606-612. Epub 2022 Apr 6.

Department of Dermatology, University of Nebraska Medical Center, Omaha, Nebraska.

Background: There is a scarcity of information regarding the clinical characteristics of rare cutaneous malignancies in skin of color that has yet to be comprehensively explored.

Objective: To review and compile the racial differences in epidemiology, clinical presentation, histology, treatments, and outcomes of 3 rare skin cancers: dermatofibrosarcoma protuberans (DFSP), Merkel cell carcinoma (MCC), and sebaceous carcinoma (SC).

Methods: Several searches with keywords denoting specific skin cancer type and race were conducted on PubMed to complete this narrative review. Read More

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Clinicopathological Features of 19 Eyelid Pilomatrixomas.

Ocul Oncol Pathol 2022 Feb 25;8(1):30-34. Epub 2021 Oct 25.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Introduction: Pilomatrixoma is a relatively rare, benign tumor arising from the hair root matrix. It is found frequently on the head and neck, with most involving the eyebrow in the periocular region. In contrast, eyelid pilomatrixoma is less common, and often clinically misdiagnosed. Read More

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February 2022

Sebaceous cell carcinoma presenting as ocular Marjolin ulcer following immunosuppression for a chemical burn.

Can J Ophthalmol 2022 Mar 26. Epub 2022 Mar 26.

University of New South Wales, Sydney, Australia; Prince of Wales Hospital, Sydney, Australia.

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Sebaceous Carcinoma Masquerading As Orbital Cellulitis.

Cureus 2022 Feb 16;14(2):e22288. Epub 2022 Feb 16.

Oculoplastics, Texas Eye Plastics, Dallas, USA.

Sebaceous cell carcinoma is an uncommonly encountered cutaneous malignancy. Often considered a great masquerader, sebaceous cell carcinoma arises from meibomian glands and can have a poor prognosis if not diagnosed early. In this case report, we present a patient with sebaceous cell carcinoma who presented to our emergency department with a clinical presentation that was concerning for orbital cellulitis. Read More

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February 2022

Sebaceous gland carcinoma: analysis based on the 8 edition of American Joint Cancer Committee classification.

Eye (Lond) 2022 Mar 26. Epub 2022 Mar 26.

Operation Eyesight Universal Institute for Eye Cancer, L V Prasad Eye Institute, Hyderabad, India.

Purpose: To assess the prognostic value of T category of the 8 edition of American Joint Committee on Cancer (AJCC) classification in periocular sebaceous gland carcinoma (SGC).

Methods: Retrospective interventional case series of 119 cases.

Results: Based on the T category of 8th edition of AJCC classification, 119 periocular SGCs were classified into T1 (n = 33, 28%), T2 (n = 37, 31%) T3 (n = 17, 14%) and T4 (n = 32, 27%). Read More

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Giant sebaceous nevus occupying half of the head associated with sebaceous carcinoma, apocrine adenocarcinoma, and basal cell carcinoma: A case report.

JPRAS Open 2022 Jun 10;32:88-92. Epub 2022 Mar 10.

Department of Plastic and Reconstructive Surgery, Kansai Medical University, Osaka, Japan.

We herein report a 57-year-old man afflicted with multiple malignant tumors arising from a giant sebaceous nevus on his left parieto-temporal scalp and neck. The upper eyelid was resected in all layers, and the auricle was resected as well, leaving part of the external auricular cartilage; the parotid gland area was also resected over the parotid fascia. The lost part of the left eyebrow was reconstructed using an anterior forehead skin flap, and the residual defect was covered with skin graft and expanded scalp flap. Read More

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