Evaluation and comparison of staining patterns of factor XIIIa (AC-1A1), adipophilin and GATA3 in sebaceous neoplasia.
- Brian J Tjarks,
- Brandy R Pownell,
- Claire Evans,
- Paul A Thompson,
- Amy M Kerkvliet,
- Michael R D Koch,
- Ali D Jassim
J Cutan Pathol 2017 Sep 5. Epub 2017 Sep 5.
Department of Pathology, University of South Dakota, Sanford School of Medicine, Sioux Falls, South Dakota.
Background: Reliable nuclear immunohistochemical stains for sebaceous neoplasms have not been readily available. Positive nuclear staining has been reported by GATA3 and factor XIIIa (AC-1A1). We sought to determine the diagnostic utility of these nuclear stains by comparing their staining pattern to adipophilin, a consistently positive cytoplasmic stain. Read More